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NS3a_protein
Euk-VirWad_Medani_virus
NS3a_protein__YP_009158893__Wad_Medani_virus__40067
Identity
- Accession:
- YP_009158893 ↗
- Protein ID:
- NS3a_protein
- Kingdom:
- euk
Quality
70.4
mean pLDDT
Taxonomy
Orthornavirae›
Duplornaviricota›
Resentoviricetes›
Reovirales›
Sedoreoviridae›
Orbivirus›
Wad_Medani_virus
TaxID: 40067
Cluster
View cluster (14 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 79-177
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01616.23 best | Orbi_NS3 | 66.4 | 3.40e-18 | 100.0% | 59.0% |
CATH (85)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4iloA00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.96 | 74.0 | 5.37e-01 | 100.0% | 33.5% |
| 2ic6A00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.91 | 56.0 | 6.56e-01 | 100.0% | 85.9% |
| 2bdeA03 | 1.20.58.1160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.91 | 54.0 | 6.17e-01 | 100.0% | 77.9% |
| 6h9xA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.90 | 58.0 | 5.74e-01 | 100.0% | 63.7% |
| 2q0oC00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.89 | 58.0 | 6.26e-01 | 96.0% | 76.7% |
| 1qsdA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.88 | 68.0 | 6.79e-01 | 96.0% | 78.4% |
| 1wleA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.88 | 72.0 | 6.81e-01 | 99.0% | 73.7% |
| 3m7gA02 | 1.10.8.1010 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.88 | 56.0 | 5.73e-01 | 85.9% | 67.4% |
| 3tulB00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.87 | 71.0 | 6.32e-01 | 100.0% | 63.2% |
| 2v6yA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.87 | 46.0 | 5.26e-01 | 73.7% | 69.3% |
| 2rd0B00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.86 | 83.0 | 7.21e-01 | 100.0% | 74.1% |
| 3u0cA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.86 | 78.0 | 6.60e-01 | 100.0% | 62.3% |
| 6r1nA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.85 | 67.0 | 6.66e-01 | 88.9% | 78.6% |
| 1ku9A02 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.85 | 50.0 | 6.22e-01 | 96.0% | 92.2% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.85 | 81.0 | 6.35e-01 | 100.0% | 56.4% |
| 2rpaA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.85 | 47.0 | 5.27e-01 | 76.8% | 70.1% |
| 1hs7A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.85 | 50.0 | 5.11e-01 | 96.0% | 60.8% |
| 1l8dA00 | 1.10.287.510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.85 | 77.0 | 7.59e-01 | 99.0% | 91.3% |
| 3lssA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.85 | 69.0 | 6.58e-01 | 88.9% | 75.0% |
| 1nt2B02 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.84 | 56.0 | 6.79e-01 | 70.7% | 100.0% |
| 1y1uA01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.84 | 79.0 | 6.14e-01 | 100.0% | 51.8% |
| 3r6nA02 | 1.20.58.1060 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.84 | 66.0 | 5.59e-01 | 100.0% | 52.9% |
| 1fxkB00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.84 | 80.0 | 7.73e-01 | 100.0% | 90.8% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.83 | 68.0 | 6.68e-01 | 90.9% | 80.4% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.83 | 56.0 | 5.44e-01 | 92.9% | 64.2% |
| 2zdiC00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.83 | 77.0 | 6.62e-01 | 100.0% | 85.1% |
| 6gy8A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.83 | 77.0 | 5.20e-01 | 100.0% | 45.2% |
| 2ke4A00 | 6.10.140.470 | Special › Helix non-globular › Helix Hairpins › | 0.83 | 71.0 | 7.20e-01 | 97.0% | 91.8% |
| 3hr0B01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.82 | 63.0 | 7.03e-01 | 80.8% | 100.0% |
| 6q45G01 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.82 | 77.0 | 6.67e-01 | 100.0% | 92.5% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.82 | 58.0 | 5.67e-01 | 86.9% | 67.3% |
| 2fb5A01 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.81 | 57.0 | 6.67e-01 | 78.8% | 100.0% |
| 1rfyB00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.81 | 57.0 | 6.03e-01 | 89.9% | 80.7% |
| 3aonA00 | 1.10.287.3240 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.81 | 75.0 | 5.96e-01 | 100.0% | 97.9% |
| 3vkgA12 | 1.10.287.2610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.81 | 74.0 | 5.61e-01 | 100.0% | 45.1% |
| 1fs0G02 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.81 | 61.0 | 6.41e-01 | 100.0% | 86.5% |
| 4lwsA00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.80 | 74.0 | 7.37e-01 | 97.0% | 98.0% |
| 4hkrA00 | 1.20.140.140 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Calcium release-activated calcium channel protein Orai | 0.80 | 55.0 | 4.58e-01 | 76.8% | 42.4% |
| 2qe7G01 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.80 | 68.0 | 6.95e-01 | 99.0% | 92.8% |
| 4jioA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.80 | 73.0 | 6.01e-01 | 94.9% | 62.7% |
| 3qo8A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.80 | 59.0 | 5.82e-01 | 92.9% | 72.6% |
| 3ajwA00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.80 | 74.0 | 6.57e-01 | 99.0% | 91.0% |
| 3k29A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.80 | 75.0 | 6.22e-01 | 100.0% | 85.7% |
| 1m5iA00 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.79 | 67.0 | 6.53e-01 | 87.9% | 100.0% |
| 4cgkA01 | 6.10.250.3150 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.79 | 74.0 | 5.61e-01 | 100.0% | 46.7% |
| 1wa8A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.79 | 59.0 | 5.98e-01 | 91.9% | 78.8% |
| 1i6zA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.79 | 60.0 | 5.32e-01 | 86.9% | 57.8% |
| 4mh6A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.78 | 72.0 | 6.08e-01 | 100.0% | 61.6% |
| 2gtsA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.78 | 58.0 | 6.50e-01 | 86.9% | 100.0% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.78 | 62.0 | 6.22e-01 | 100.0% | 82.4% |
| 3r84A00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.78 | 59.0 | 6.42e-01 | 97.0% | 97.5% |
| 1hciA03 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.78 | 59.0 | 5.51e-01 | 97.0% | 65.8% |
| 2odvA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.78 | 56.0 | 5.37e-01 | 92.9% | 66.1% |
| 7sgrA02 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.77 | 68.0 | 4.71e-01 | 97.0% | 30.3% |
| 1owaA02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.77 | 54.0 | 5.36e-01 | 81.8% | 68.9% |
| 2gd5A00 | 6.10.140.1230 | Special › Helix non-globular › Helix Hairpins › | 0.77 | 71.0 | 6.19e-01 | 99.0% | 99.3% |
| 3nrxA00 | 1.20.58.1520 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 55.0 | 5.11e-01 | 83.8% | 61.0% |
| 6xj1A01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.75 | 69.0 | 5.10e-01 | 100.0% | 43.3% |
| 2fcwA00 | 1.20.81.10 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain | 0.75 | 61.0 | 6.02e-01 | 89.9% | 81.1% |
| 3layF00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.75 | 47.0 | 5.23e-01 | 100.0% | 80.8% |
| 1a36A04 | 1.10.132.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.75 | 51.0 | 4.19e-01 | 100.0% | 39.4% |
| 4dylA02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.75 | 65.0 | 6.72e-01 | 96.0% | 97.9% |
| 6v9zA02 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.75 | 66.0 | 4.54e-01 | 96.0% | 94.5% |
| 2ieqA00 | 1.20.5.300 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.74 | 61.0 | 6.42e-01 | 93.9% | 98.9% |
| 3pltA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.74 | 66.0 | 5.12e-01 | 99.0% | 45.3% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.74 | 68.0 | 5.07e-01 | 99.0% | 56.1% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 65.0 | 5.39e-01 | 97.0% | 56.6% |
| 4nqiD00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.72 | 65.0 | 4.93e-01 | 99.0% | 43.1% |
| 4mrsA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.71 | 65.0 | 4.41e-01 | 99.0% | 93.0% |
| 3zdqA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.71 | 62.0 | 4.26e-01 | 96.0% | 94.6% |
| 5y06A01 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.71 | 63.0 | 4.81e-01 | 100.0% | 42.8% |
| 2gl2B00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.71 | 60.0 | 5.85e-01 | 97.0% | 84.4% |
| 4ke2A00 | 6.10.140.1860 | Special › Helix non-globular › Helix Hairpins › | 0.70 | 58.0 | 4.57e-01 | 87.9% | 46.4% |
| 1zkeA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 51.0 | 5.71e-01 | 98.0% | 92.6% |
| 1tqgA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.70 | 50.0 | 4.91e-01 | 73.7% | 100.0% |
| 1jadA00 | 1.20.1230.10 | Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain | 0.66 | 56.0 | 4.20e-01 | 91.9% | 55.0% |
| 5dn6J00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.66 | 47.0 | 5.37e-01 | 75.8% | 100.0% |
| 3okqA00 | 1.20.58.1540 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain | 0.66 | 57.0 | 5.33e-01 | 98.0% | 80.0% |
| 8fbnB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.65 | 55.0 | 4.06e-01 | 100.0% | 39.2% |
| 1wpaA01 | 6.10.140.340 | Special › Helix non-globular › Helix Hairpins › | 0.64 | 57.0 | 5.79e-01 | 97.0% | 96.0% |
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.63 | 45.0 | 5.08e-01 | 75.8% | 100.0% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.63 | 55.0 | 4.96e-01 | 94.9% | 70.7% |
| 2wgmA01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.60 | 46.0 | 5.00e-01 | 80.8% | 97.6% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.58 | 46.0 | 4.68e-01 | 85.9% | 99.0% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.55 | 46.0 | 4.48e-01 | 96.0% | 82.6% |
ECOD (80)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3176480 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.97 | 75.0 | 7.90e-01 | 100.0% | 87.6% |
| 4977416 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.97 | 77.0 | 5.55e-01 | 100.0% | 33.9% |
| 3919840 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.92 | 73.0 | 5.39e-01 | 100.0% | 36.8% |
| 4401282 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.92 | 74.0 | 6.96e-01 | 97.0% | 71.3% |
| 3731644 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.91 | 75.0 | 6.06e-01 | 100.0% | 49.4% |
| 4031283 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.89 | 82.0 | 6.97e-01 | 100.0% | 64.0% |
| 4465072 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.89 | 73.0 | 6.87e-01 | 100.0% | 73.0% |
| 4992667 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.88 | 82.0 | 5.69e-01 | 100.0% | 34.5% |
| 4974450 | 3291.1.1.4 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30 | 0.88 | 82.0 | 6.55e-01 | 100.0% | 54.9% |
| 4055098 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.87 | 78.0 | 7.09e-01 | 100.0% | 73.6% |
| 3634628 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.87 | 80.0 | 5.08e-01 | 100.0% | 23.2% |
| 3611166 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.87 | 83.0 | 6.35e-01 | 100.0% | 74.0% |
| 3251869 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.87 | 83.0 | 6.19e-01 | 100.0% | 60.5% |
| 3512620 | 3755.4.1.1 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PI3K_P85_iSH2 | 0.86 | 82.0 | 6.81e-01 | 100.0% | 66.9% |
| 3240634 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.86 | 82.0 | 6.88e-01 | 100.0% | 68.4% |
| 3207855 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.86 | 82.0 | 6.95e-01 | 100.0% | 84.7% |
| 3704098 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.86 | 78.0 | 6.35e-01 | 100.0% | 55.9% |
| 3711734 | 3755.3.1.297 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF9 | 0.86 | 82.0 | 6.68e-01 | 100.0% | 62.4% |
| 3699472 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.85 | 81.0 | 4.97e-01 | 100.0% | 32.1% |
| 4085442 | 3291.1.1.189 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › CC_PcsB | 0.85 | 76.0 | 7.02e-01 | 92.9% | 88.3% |
| 4145667 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.85 | 81.0 | 6.27e-01 | 100.0% | 74.9% |
| 3554294 | 603.2.1.1 ↗ | alpha bundles › STAT-like › STAT › STAT › STAT_alpha | 0.85 | 80.0 | 6.20e-01 | 100.0% | 50.5% |
| 4998774 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.84 | 72.0 | 4.50e-01 | 100.0% | 18.8% |
| 3495507 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.84 | 81.0 | 6.58e-01 | 100.0% | 61.8% |
| 4324499 | 3755.1.1.3 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › SPAM | 0.84 | 80.0 | 6.89e-01 | 100.0% | 82.8% |
| 4008904 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.84 | 79.0 | 5.39e-01 | 100.0% | 36.2% |
| 4310983 | 2004.1.1.567 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23 | 0.84 | 80.0 | 4.77e-01 | 100.0% | 21.4% |
| 4944766 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.84 | 77.0 | 5.90e-01 | 100.0% | 46.8% |
| 4448955 | 2004.1.1.480 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_29 | 0.84 | 80.0 | 5.08e-01 | 100.0% | 27.2% |
| 4957994 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.84 | 80.0 | 5.36e-01 | 100.0% | 82.8% |
| 4969098 | 3926.1.1.0 ↗ | alpha bundles › V-type proton ATPase subunit D › V-type proton ATPase subunit D › V-type proton ATPase subunit D | 0.84 | 80.0 | 6.41e-01 | 100.0% | 62.3% |
| 3186867 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.84 | 72.0 | 5.90e-01 | 100.0% | 53.9% |
| 3608116 | 5086.1.1.177 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › KIF9 | 0.83 | 79.0 | 6.82e-01 | 100.0% | 71.0% |
| 4559671 | 2004.1.1.567 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23 | 0.83 | 78.0 | 4.52e-01 | 100.0% | 35.3% |
| 4943562 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.83 | 79.0 | 6.02e-01 | 100.0% | 65.4% |
| 3889547 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.83 | 78.0 | 6.14e-01 | 100.0% | 81.6% |
| 4940230 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.83 | 79.0 | 5.96e-01 | 100.0% | 87.6% |
| 4941675 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.83 | 79.0 | 4.85e-01 | 100.0% | 20.4% |
| 3699443 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.82 | 73.0 | 6.87e-01 | 92.9% | 79.1% |
| 3559082 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.82 | 78.0 | 6.23e-01 | 100.0% | 56.7% |
| 3908132 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.82 | 78.0 | 5.58e-01 | 100.0% | 88.2% |
| 3913300 | 3755.3.1.303 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A_4th | 0.82 | 76.0 | 6.46e-01 | 99.0% | 90.7% |
| 3697399 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.81 | 76.0 | 6.37e-01 | 100.0% | 68.8% |
| 4606154 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.81 | 68.0 | 5.61e-01 | 100.0% | 52.4% |
| 5066104 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.81 | 75.0 | 4.60e-01 | 99.0% | 20.0% |
| 3459621 | 3826.1.1.0 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) | 0.80 | 50.0 | 5.02e-01 | 100.0% | 62.0% |
| 5062668 | 3755.1.1.0 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related | 0.80 | 75.0 | 6.88e-01 | 100.0% | 84.8% |
| 3596574 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.80 | 74.0 | 6.16e-01 | 100.0% | 70.9% |
| 3337008 | 192.2.1.60 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › KIF21A_4th | 0.79 | 74.0 | 6.53e-01 | 100.0% | 72.1% |
| 4015122 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.79 | 73.0 | 6.58e-01 | 98.0% | 91.5% |
| 5002671 | 3755.3.1.637 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 | 0.79 | 74.0 | 6.18e-01 | 100.0% | 75.6% |
| 3596488 | 3737.1.1.0 ↗ | alpha duplicates or obligate multimers › Major allergen Bla g 1 tandem repeats › Major allergen Bla g 1 tandem repeats › Major allergen Bla g 1 tandem repeats | 0.79 | 75.0 | 6.83e-01 | 100.0% | 80.0% |
| 3318812 | 192.8.1.248 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › KIF21A_4th | 0.78 | 73.0 | 6.27e-01 | 100.0% | 67.3% |
| 3942242 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.78 | 72.0 | 6.36e-01 | 100.0% | 70.7% |
| 3350514 | 3922.1.1.145 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › KIF21A_4th | 0.77 | 73.0 | 6.06e-01 | 100.0% | 63.1% |
| 3906810 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.77 | 71.0 | 6.30e-01 | 100.0% | 72.1% |
| 3831567 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.77 | 72.0 | 5.90e-01 | 100.0% | 90.0% |
| 3168460 | 2004.1.1.429 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15 | 0.77 | 72.0 | 4.18e-01 | 100.0% | 13.1% |
| 3793986 | 604.7.1.7 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › Mitofilin | 0.77 | 66.0 | 5.89e-01 | 100.0% | 67.4% |
| 4374392 | 2004.1.1.429 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15 | 0.77 | 72.0 | 4.64e-01 | 100.0% | 24.6% |
| 3574610 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.77 | 72.0 | 5.58e-01 | 100.0% | 50.0% |
| 3908626 | 3755.3.1.483 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PF30493 | 0.77 | 69.0 | 5.10e-01 | 100.0% | 40.8% |
| 4676629 | 3755.3.1.290 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PPI_helical | 0.76 | 71.0 | 5.28e-01 | 100.0% | 57.0% |
| 3659069 | 604.7.1.1 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA | 0.75 | 66.0 | 6.24e-01 | 97.0% | 80.0% |
| 4862474 | 3291.1.1.4 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30 | 0.75 | 68.0 | 6.03e-01 | 100.0% | 77.5% |
| 4022925 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.75 | 70.0 | 5.34e-01 | 100.0% | 47.1% |
| 3970019 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.75 | 68.0 | 5.14e-01 | 100.0% | 44.8% |
| 4996626 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.74 | 70.0 | 5.04e-01 | 100.0% | 38.8% |
| 3912535 | 603.2.1.1 ↗ | alpha bundles › STAT-like › STAT › STAT › STAT_alpha | 0.73 | 66.0 | 5.30e-01 | 100.0% | 52.8% |
| 3699457 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.73 | 66.0 | 6.21e-01 | 99.0% | 92.5% |
| 3239791 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.73 | 67.0 | 5.41e-01 | 99.0% | 56.7% |
| 3916825 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.73 | 66.0 | 5.73e-01 | 100.0% | 66.7% |
| 5040840 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.73 | 66.0 | 3.93e-01 | 100.0% | 14.2% |
| 4178099 | 632.22.1.176 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › PF27734 | 0.73 | 66.0 | 5.69e-01 | 100.0% | 65.8% |
| 4946656 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.71 | 60.0 | 5.62e-01 | 91.9% | 75.8% |
| 5057329 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.68 | 60.0 | 5.35e-01 | 100.0% | 67.6% |
| 3988263 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.68 | 61.0 | 5.06e-01 | 100.0% | 56.6% |
| 3784055 | 192.24.1.0 ↗ | alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain | 0.67 | 61.0 | 5.60e-01 | 100.0% | 88.5% |
| 4936792 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.66 | 58.0 | 4.83e-01 | 100.0% | 53.5% |
| 4392833 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.64 | 56.0 | 4.41e-01 | 99.0% | 61.9% |