NS5-like_protein

Euk-Vir

Wuhan_aphid_virus_2

NS5-like_protein__YP_009179378__Wuhan_aphid_virus_2__1746068

Identity

75.1 mean pLDDT

Orthornavirae› Kitrinoviricota› Flasuviricetes› Amarillovirales› Flaviviridae› Wuhan_aphid_virus_2

TaxID: 1746068

View cluster (51 members)

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high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 84-277

PDB

Domain cluster: rep: RNA-dependent_RNA_polymerase_NS5__YP_009259288__Mercadeo_virus__1708574__D63-201

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01728.26 best	FtsJ	43.2	5.90e-11	90.2%	97.2%

D2 medium residues 27-83

PDB

D3 medium residues 310-349_368-394_426-498

PDB

Domain cluster: rep: NS5-like_protein__YP_009179403__Wuhan_flea_virus__1746071__D315-356_368-395_444-456_471-503_597-617

D4 medium residues 395-425_499-662

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00972.26 best	Flavi_NS5	32.6	4.90e-08	85.6%	34.4%

CATH (2)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3sqnA02	1.10.1790.40	Mainly Alpha › Orthogonal Bundle › PTS-regulatory domain, PRD ›	0.60	26.0	3.26e-01	89.2%	62.7%
4qjvB00	3.30.1360.10	Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit	0.53	26.0	3.55e-01	74.9%	93.6%

ECOD (6)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1173784	304.48.1.8 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1	0.80	77.0	6.04e-01	100.0%	73.4%
3789227	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.68	63.0	5.38e-01	100.0%	88.1%
4070164	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.64	51.0	4.16e-01	83.1%	67.2%
4016275	109.4.1.2191 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HAT, TPR_14, TPR_19, HAT_Syf1_CNRKL1_C, HAT_Syf1_CNRKL1_N, HAT_PRP39_N, HAT_PRP39_C	0.54	24.0	1.63e-01	71.3%	11.1%
4948264	878.1.1.1 ↗	a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194	0.53	21.0	3.32e-01	88.7%	91.3%
3238364	109.4.1.32 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MIF4G	0.52	28.0	2.33e-01	74.4%	28.0%

D5 medium residues 794-851_867-907

PDB