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NSP15
Euk-VirTurkey_coronavirus
NSP15__YP_001941188__Turkey_coronavirus__11152
Identity
- Accession:
- YP_001941188 ↗
- Protein ID:
- NSP15
- Kingdom:
- euk
Quality
94.0
mean pLDDT
Taxonomy
Orthornavirae›
Pisuviricota›
Pisoniviricetes›
Nidovirales›
Coronaviridae›
Gammacoronavirus›
Turkey_coronavirus
TaxID: 11152
Cluster
View cluster (23 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 1-59
Domain cluster:
rep: putative_coronavirus_nsp12__NP_839968__Porcine_epidemic_diarrhea_virus__28295__D1-51
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF19219.6 best | CoV_NSP15_N | 84.2 | 7.80e-24 | 100.0% | 96.7% |
D2
high
residues 65-176
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF19216.6 best | CoV_NSP15_M | 109.6 | 1.60e-31 | 98.2% | 94.9% |
CATH (25)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2gtiA02 | 3.40.50.11580 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › nsp15 middle domain | 0.94 | 90.0 | 8.45e-01 | 100.0% | 89.3% |
| 2h85A02 | 3.40.50.11580 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › nsp15 middle domain | 0.93 | 89.0 | 8.50e-01 | 100.0% | 96.8% |
| 4rs4B02 | 3.40.50.11580 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › nsp15 middle domain | 0.89 | 85.0 | 8.12e-01 | 100.0% | 96.8% |
| 1o54A02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.65 | 58.0 | 4.85e-01 | 99.1% | 92.2% |
| 3e05B00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.63 | 57.0 | 4.77e-01 | 100.0% | 89.6% |
| 1qamA01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.63 | 55.0 | 4.99e-01 | 98.2% | 98.1% |
| 1xcjA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.62 | 55.0 | 4.38e-01 | 98.2% | 83.4% |
| 2i6gB00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.62 | 54.0 | 4.49e-01 | 96.4% | 91.0% |
| 1d2gA02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.62 | 54.0 | 4.60e-01 | 98.2% | 96.8% |
| 3bt7A01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.61 | 54.0 | 4.33e-01 | 99.1% | 79.0% |
| 3ajdA02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.60 | 53.0 | 4.45e-01 | 97.3% | 99.0% |
| 2i62A00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.59 | 52.0 | 4.03e-01 | 98.2% | 86.8% |
| 3ihtA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.59 | 52.0 | 4.64e-01 | 100.0% | 91.4% |
| 2aznA00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.56 | 49.0 | 4.01e-01 | 99.1% | 85.8% |
| 2hxvA02 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.56 | 50.0 | 4.17e-01 | 100.0% | 85.4% |
| 8db3B02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.55 | 46.0 | 3.84e-01 | 92.9% | 73.6% |
| 5znqA00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.55 | 45.0 | 3.87e-01 | 89.3% | 74.3% |
| 2w0mA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 48.0 | 3.91e-01 | 100.0% | 73.2% |
| 3ga2A00 | 3.30.2170.10 | Alpha Beta › 2-Layer Sandwich › archaeoglobus fulgidus dsm 4304 fold › archaeoglobus fulgidus dsm 4304 superfamily | 0.54 | 46.0 | 3.62e-01 | 93.8% | 69.5% |
| 2cvhA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.52 | 40.0 | 3.32e-01 | 83.9% | 86.9% |
| 4a8jF00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.52 | 46.0 | 3.55e-01 | 100.0% | 80.2% |
| 4wiaC00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.52 | 46.0 | 3.70e-01 | 100.0% | 74.8% |
| 2dr3A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.50 | 41.0 | 3.33e-01 | 91.1% | 61.6% |
| 3ptyA01 | 3.40.190.160 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › | 0.50 | 38.0 | 3.88e-01 | 98.2% | 85.8% |
| 4ydsA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.50 | 38.0 | 3.17e-01 | 83.9% | 96.5% |
ECOD (28)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4872108 | 2003.1.5.85 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases | 0.93 | 89.0 | 7.09e-01 | 100.0% | 61.0% |
| 1712060 | 2003.1.5.85 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases | 0.89 | 85.0 | 6.99e-01 | 100.0% | 63.6% |
| 3593753 | 2003.1.5.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases | 0.66 | 58.0 | 4.60e-01 | 98.2% | 79.6% |
| 5083140 | 2004.1.1.146 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase | 0.60 | 50.0 | 4.06e-01 | 92.9% | 79.6% |
| 4977959 | 2004.1.1.146 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase | 0.59 | 50.0 | 4.03e-01 | 93.8% | 74.8% |
| 5076625 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.57 | 46.0 | 3.59e-01 | 87.5% | 84.3% |
| 4978792 | 2004.1.1.146 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase | 0.57 | 45.0 | 3.65e-01 | 86.6% | 83.3% |
| 5063695 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.57 | 50.0 | 4.27e-01 | 99.1% | 84.2% |
| 4988628 | 328.5.1.6 ↗ | a+b two layers › IF3-like › SirA-like › SirA-like › DUF2249 | 0.57 | 33.0 | 4.22e-01 | 86.6% | 100.0% |
| 4989786 | 2004.1.1.146 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase | 0.57 | 48.0 | 4.02e-01 | 92.9% | 75.9% |
| 5062848 | 2004.1.1.146 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase | 0.57 | 48.0 | 3.87e-01 | 93.8% | 72.0% |
| 4996593 | 2004.1.1.146 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase | 0.57 | 47.0 | 3.77e-01 | 93.8% | 77.5% |
| 5078727 | 2004.1.1.146 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase | 0.56 | 50.0 | 4.00e-01 | 100.0% | 77.3% |
| 4993530 | 2004.1.1.146 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase | 0.56 | 44.0 | 3.56e-01 | 87.5% | 82.8% |
| 4209889 | 7501.1.1.0 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases | 0.55 | 48.0 | 4.45e-01 | 99.1% | 89.0% |
| 4186194 | 2004.1.1.146 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase | 0.55 | 46.0 | 3.70e-01 | 92.9% | 70.9% |
| 4938977 | 2004.1.1.146 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase | 0.55 | 43.0 | 3.50e-01 | 88.4% | 82.5% |
| 5055709 | 2004.1.1.146 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase | 0.54 | 48.0 | 3.88e-01 | 100.0% | 74.2% |
| 4934507 | 2004.1.1.146 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase | 0.54 | 42.0 | 3.37e-01 | 86.6% | 93.1% |
| 4563316 | 7501.1.1.1 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 | 0.53 | 46.0 | 4.11e-01 | 98.2% | 81.8% |
| 4295510 | 7501.1.1.1 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 | 0.53 | 46.0 | 4.15e-01 | 99.1% | 83.1% |
| 5020938 | 2004.1.1.146 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase | 0.53 | 42.0 | 3.35e-01 | 85.7% | 97.4% |
| 5031877 | 2004.1.1.146 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase | 0.52 | 45.0 | 3.69e-01 | 100.0% | 75.6% |
| 4976926 | 2004.1.1.146 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase | 0.51 | 40.0 | 3.26e-01 | 87.5% | 96.7% |
| 4998490 | 2004.1.1.146 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase | 0.51 | 40.0 | 3.21e-01 | 85.7% | 98.0% |
| 4933476 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.51 | 43.0 | 3.59e-01 | 93.8% | 68.5% |
| 4947956 | 2004.1.1.146 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase | 0.50 | 41.0 | 3.29e-01 | 91.1% | 63.3% |
| 5012558 | 2004.1.1.146 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase | 0.50 | 39.0 | 3.23e-01 | 85.7% | 97.8% |
D3
high
residues 197-334
Domain cluster:
rep: coronavirus_nsp12__NP_740632__Infectious_bronchitis_virus__11120__D198-335
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF19215.6 best | CoV_NSP15_C | 144.6 | 3.50e-42 | 100.0% | 87.7% |