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NSP8

Euk-Vir

Duck_coronavirus

NSP8__YP_009825036__Duck_coronavirus__300188

Identity

Accession:
YP_009825036 ↗
Protein ID:
NSP8
Kingdom:
euk

Quality

79.4 mean pLDDT

Taxonomy

Orthornavirae› Pisuviricota› Pisoniviricetes› Nidovirales› Coronaviridae› Gammacoronavirus› Duck_coronavirus

TaxID: 300188

Cluster

View cluster (35 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 2-101
PDB
Domain cluster: rep: putative_coronavirus_nsp5__NP_839962__Porcine_epidemic_diarrhea_virus__28295__D10-97
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF08717.17 best CoV_NSP8 129.9 1.40e-37 100.0% 48.2%
D2 high residues 118-199
PDB
Domain cluster: rep: nsp8__YP_009555251__Human_coronavirus_OC43__31631__D117-187
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF08717.17 best CoV_NSP8 69.3 5.10e-19 100.0% 38.7%
CATH (26)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ahmH02 3.30.70.3540 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nsp8 replicase, head domain 0.76 71.0 6.75e-01 98.8% 94.6%
3ub0A02 3.30.70.3540 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nsp8 replicase, head domain 0.73 68.0 6.52e-01 98.8% 92.4%
1r5bA02 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.65 49.0 4.81e-01 97.6% 73.0%
4b43A03 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.63 46.0 4.10e-01 100.0% 54.8%
3jxoA00 3.30.70.1450 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Regulator of K+ conductance, C-terminal domain 0.62 46.0 4.66e-01 89.0% 77.4%
2dazA01 2.30.42.10 Mainly Beta › Roll › Pdz3 Domain › PDZ domain 0.62 50.0 4.49e-01 86.6% 76.8%
4g65A04 3.30.70.1450 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Regulator of K+ conductance, C-terminal domain 0.61 49.0 4.77e-01 100.0% 79.1%
2ausC02 3.30.2350.10 Alpha Beta › 2-Layer Sandwich › Pseudouridine synthase › Pseudouridine synthase 0.58 39.0 3.05e-01 93.9% 29.7%
4he6A00 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.58 44.0 4.34e-01 96.3% 74.2%
1zunB02 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.58 44.0 4.29e-01 97.6% 73.3%
4bi3A01 3.90.1720.80 Alpha Beta › Alpha-Beta Complex › endopeptidase fold (from Nostoc punctiforme) › 0.57 43.0 4.24e-01 86.6% 74.7%
2ijd101 2.40.10.120 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.55 44.0 3.36e-01 100.0% 38.3%
4e8dA03 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.55 49.0 4.13e-01 100.0% 71.7%
3ajdA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 46.0 3.64e-01 100.0% 88.1%
4uzgA01 2.60.40.740 Mainly Beta › Sandwich › Immunoglobulin-like › 0.55 46.0 3.85e-01 98.8% 75.6%
2nutB03 2.60.40.1670 Mainly Beta › Sandwich › Immunoglobulin-like › beta-sandwich domain of Sec23/24 0.54 47.0 4.08e-01 100.0% 71.4%
6ijfC01 3.90.1720.80 Alpha Beta › Alpha-Beta Complex › endopeptidase fold (from Nostoc punctiforme) › 0.54 40.0 3.91e-01 84.1% 71.0%
3jqwC00 2.60.120.380 Mainly Beta › Sandwich › Jelly Rolls › 0.53 46.0 4.15e-01 100.0% 89.3%
3afgA03 2.60.120.380 Mainly Beta › Sandwich › Jelly Rolls › 0.53 44.0 4.18e-01 97.6% 76.5%
2bvbA00 2.60.120.710 Mainly Beta › Sandwich › Jelly Rolls › Toxoplasma gondii micronemal protein 1 TgMIC1 0.52 44.0 3.78e-01 97.6% 86.1%
3thpA02 2.60.120.1520 Mainly Beta › Sandwich › Jelly Rolls › 0.52 43.0 3.53e-01 91.5% 64.5%
1ogpA02 2.60.40.650 Mainly Beta › Sandwich › Immunoglobulin-like › 0.52 43.0 3.79e-01 100.0% 60.6%
4w6yA00 2.60.120.1210 Mainly Beta › Sandwich › Jelly Rolls › 0.52 43.0 3.59e-01 92.7% 93.8%
1h7zA00 2.60.90.10 Mainly Beta › Sandwich › Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) › Adenovirus pIV-related, attachment domain 0.51 43.0 3.42e-01 100.0% 90.6%
1z9mA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.50 42.0 3.90e-01 93.9% 83.7%
1ykwA01 3.30.70.150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RuBisCO large subunit, N-terminal domain 0.50 39.0 3.36e-01 86.6% 52.7%
ECOD (54)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4881031 4315.1.1.1 ↗ beta barrels › Coronavirus NSP8-like › Coronavirus NSP8-like › Coronavirus NSP8-like › CoV_NSP8 0.91 81.0 5.92e-01 93.9% 39.5%
2605331 4315.1.1.1 ↗ beta barrels › Coronavirus NSP8-like › Coronavirus NSP8-like › Coronavirus NSP8-like › CoV_NSP8 0.81 67.0 5.73e-01 93.9% 57.1%
3031755 4315.1.1.1 ↗ beta barrels › Coronavirus NSP8-like › Coronavirus NSP8-like › Coronavirus NSP8-like › CoV_NSP8 0.81 67.0 5.93e-01 93.9% 63.2%
3108982 4315.1.1.1 ↗ beta barrels › Coronavirus NSP8-like › Coronavirus NSP8-like › Coronavirus NSP8-like › CoV_NSP8 0.81 67.0 5.03e-01 93.9% 39.1%
2818339 4315.1.1.1 ↗ beta barrels › Coronavirus NSP8-like › Coronavirus NSP8-like › Coronavirus NSP8-like › CoV_NSP8 0.81 68.0 6.84e-01 95.1% 90.1%
4876705 4315.1.1.1 ↗ beta barrels › Coronavirus NSP8-like › Coronavirus NSP8-like › Coronavirus NSP8-like › CoV_NSP8 0.81 67.0 5.90e-01 95.1% 62.4%
3589619 4261.1.1.1 ↗ a+b two layers › TrkA C-terminal domain-like › TrkA C-terminal domain-like › TrkA C-terminal domain-like › TrkA_C 0.64 44.0 4.49e-01 86.6% 72.5%
5029965 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.64 46.0 4.59e-01 100.0% 72.9%
4944709 4261.1.1.0 ↗ a+b two layers › TrkA C-terminal domain-like › TrkA C-terminal domain-like › TrkA C-terminal domain-like 0.63 46.0 4.22e-01 89.0% 58.2%
4018119 219.1.1.0 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.62 55.0 3.56e-01 100.0% 47.1%
5022443 1.1.7.50 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › EF-G_D2 0.62 45.0 4.44e-01 96.3% 71.1%
3991400 7526.1.1.0 ↗ a/b three-layered sandwiches › Initiation factor IF2/eIF5b, domain 3 › Initiation factor IF2/eIF5b, domain 3 › Initiation factor IF2/eIF5b, domain 3 0.61 46.0 3.18e-01 100.0% 24.6%
4166205 1.1.7.50 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › EF-G_D2 0.61 45.0 4.05e-01 100.0% 57.3%
3275318 1.1.7.50 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › EF-G_D2 0.61 45.0 3.78e-01 100.0% 45.7%
4984273 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.60 45.0 4.50e-01 97.6% 76.5%
3629516 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.60 53.0 5.03e-01 98.8% 83.2%
5056886 219.1.1.51 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C39_2 0.60 47.0 3.55e-01 86.6% 54.6%
3962338 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.59 44.0 3.76e-01 100.0% 47.4%
3476360 1.1.7.50 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › EF-G_D2 0.58 44.0 4.04e-01 96.3% 60.9%
3684288 12.1.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.58 50.0 4.61e-01 100.0% 74.3%
3978784 1.1.7.36 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Peptidase_U32_C 0.57 41.0 3.78e-01 98.8% 57.4%
3600073 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.57 50.0 4.34e-01 97.6% 64.8%
3242646 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.57 47.0 4.88e-01 96.3% 98.7%
4960841 4081.1.1.0 ↗ beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related 0.56 51.0 3.94e-01 100.0% 46.7%
3992541 10.32.1.205 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › Ams1-like_1st 0.56 51.0 4.20e-01 100.0% 57.2%
4944856 12.1.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.56 51.0 4.46e-01 100.0% 91.7%
4214734 11.1.5.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f 0.56 47.0 4.19e-01 100.0% 78.3%
4282509 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.55 44.0 2.70e-01 90.2% 15.9%
3965265 110.2.1.0 ↗ alpha arrays › DEATH domain › Replication modulator SeqA-C › Replication modulator SeqA-C 0.55 38.0 3.84e-01 73.2% 98.8%
None — 0.55 49.0 3.67e-01 100.0% 76.6%
5046033 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.54 47.0 4.15e-01 100.0% 78.5%
3824997 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.54 46.0 2.80e-01 97.6% 20.0%
5048740 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.54 47.0 4.26e-01 100.0% 83.5%
4940606 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.53 46.0 4.08e-01 100.0% 75.8%
401494 10.32.1.19 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › PPC 0.53 46.0 4.15e-01 100.0% 89.3%
5048739 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.53 47.0 4.05e-01 100.0% 73.8%
5041352 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.53 46.0 4.05e-01 100.0% 90.4%
4977719 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.53 45.0 4.21e-01 96.3% 99.0%
4929726 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.53 46.0 4.25e-01 97.6% 76.2%
4382620 10.32.1.4 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › EMP24_GP25L 0.53 45.0 4.34e-01 96.3% 88.4%
3433491 10.32.1.4 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › EMP24_GP25L 0.52 44.0 4.08e-01 96.3% 80.0%
4217174 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.52 40.0 4.30e-01 86.6% 100.0%
5014927 10.1.2.183 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) › PPC 0.52 45.0 4.10e-01 97.6% 72.7%
4568752 10.32.1.19 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › PPC 0.52 45.0 4.10e-01 97.6% 72.7%
3609787 10.32.1.4 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › EMP24_GP25L 0.52 45.0 3.88e-01 100.0% 63.7%
5044062 12.1.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.52 46.0 4.39e-01 98.8% 91.6%
4943500 11.1.5.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f 0.52 43.0 4.35e-01 97.6% 92.9%
5068228 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.51 43.0 4.00e-01 97.6% 73.3%
3710159 10.32.1.4 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › EMP24_GP25L 0.51 44.0 4.04e-01 96.3% 80.0%
4103741 10.32.1.19 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › PPC 0.51 43.0 4.06e-01 97.6% 75.2%
3708922 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.51 43.0 3.79e-01 97.6% 71.5%
5048738 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.51 39.0 4.01e-01 86.6% 92.5%
5047474 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.50 42.0 4.10e-01 97.6% 86.3%
4968789 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.50 44.0 4.08e-01 100.0% 88.6%