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NS

Euk-Vir

Seal_parvovirus

NS__YP_010086570__Seal_parvovirus__1427158

Identity

Accession:
YP_010086570 ↗
Protein ID:
NS
Kingdom:
euk

Quality

60.1 mean pLDDT

Taxonomy

Shotokuvirae› Cossaviricota› Quintoviricetes› Piccovirales› Parvoviridae› Erythroparvovirus› Seal_parvovirus

TaxID: 1427158

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 12-44_56-201
PDB
D2 medium residues 224-274
PDB
Domain cluster: representative
CATH (26)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1u0jA01 1.10.10.950 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.77 67.0 6.54e-01 98.0% 90.9%
3a06B03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.72 45.0 3.70e-01 78.4% 36.4%
4edgA03 1.20.50.20 Mainly Alpha › Up-down Bundle › Pheromone ER-1 › DnaG, RNA polymerase domain, helical bundle 0.68 44.0 4.18e-01 78.4% 55.0%
2gxaE01 1.10.10.510 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Zinc finger, large T-antigen D1 domain 0.68 59.0 5.27e-01 100.0% 78.1%
4hehA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.67 57.0 4.93e-01 98.0% 72.3%
1svmA01 1.10.10.510 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Zinc finger, large T-antigen D1 domain 0.61 51.0 4.39e-01 100.0% 87.8%
1g5bB00 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.61 50.0 3.41e-01 100.0% 29.0%
7xcnM01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.60 48.0 4.31e-01 94.1% 75.6%
2gtvX00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.60 49.0 4.06e-01 100.0% 65.4%
2iw3A02 1.20.1390.20 Mainly Alpha › Up-down Bundle › PWI domain › 0.59 48.0 4.19e-01 100.0% 81.1%
1x4oA00 1.10.10.790 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Surp module 0.57 46.0 4.15e-01 98.0% 70.5%
7lwzB01 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.57 40.0 2.78e-01 78.4% 20.7%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 48.0 3.58e-01 94.1% 58.6%
2vl7A02 1.10.275.30 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › 0.57 43.0 3.36e-01 88.2% 38.2%
2dt7B01 1.10.10.790 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Surp module 0.57 48.0 4.65e-01 100.0% 86.4%
2yi9A05 1.20.1270.270 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › VP1, C-terminal extension domain 0.57 39.0 3.42e-01 76.5% 48.1%
1hs7A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 48.0 3.96e-01 100.0% 76.3%
1qdmA03 1.10.225.10 Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like 0.56 46.0 4.16e-01 100.0% 64.9%
2r7rA08 1.20.120.1400 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.55 45.0 3.96e-01 98.0% 83.7%
6fucA02 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.55 43.0 3.10e-01 96.1% 80.4%
3ddhA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.55 46.0 3.96e-01 94.1% 92.6%
2wgmA01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.55 40.0 3.50e-01 82.4% 50.0%
3fxdB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 42.0 4.07e-01 86.3% 94.8%
2mtqA00 1.20.58.130 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 46.0 4.11e-01 100.0% 80.8%
1wp7A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.52 41.0 3.86e-01 88.2% 84.4%
1vjtA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 43.0 3.40e-01 100.0% 72.4%
ECOD (20)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4880005 10.2.1.16 ↗ beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Parvo_NS1 0.82 72.0 5.07e-01 100.0% 33.5%
4955688 2.21.1.5 ↗ beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) › PF27234 0.67 58.0 4.10e-01 100.0% 33.3%
4993593 198.1.1.27 ↗ alpha arrays › Saposin-like › Saposin-like › Saposin-like › PF27234 0.66 56.0 4.90e-01 100.0% 66.3%
5003639 2.21.1.0 ↗ beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) 0.65 56.0 4.03e-01 100.0% 34.8%
5002559 2.21.1.0 ↗ beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) 0.65 56.0 3.97e-01 100.0% 33.3%
4933155 198.1.1.27 ↗ alpha arrays › Saposin-like › Saposin-like › Saposin-like › PF27234 0.63 55.0 4.68e-01 100.0% 63.5%
5009771 2.21.1.5 ↗ beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) › PF27234 0.63 54.0 3.82e-01 100.0% 32.4%
5080157 7000.1.1.0 ↗ alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS 0.63 53.0 4.87e-01 100.0% 81.4%
3814136 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.62 55.0 5.41e-01 100.0% 92.7%
4934319 101.1.2.947 ↗ alpha arrays › HTH › HTH › winged helix domain › PF27234 0.61 47.0 4.45e-01 88.2% 76.2%
5040698 7000.1.1.0 ↗ alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS 0.60 50.0 4.87e-01 100.0% 88.3%
4974313 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.60 48.0 4.70e-01 90.2% 81.8%
3701737 103.1.1.0 ↗ alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.59 40.0 3.58e-01 70.6% 57.1%
4933787 2.21.1.0 ↗ beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) 0.58 50.0 3.51e-01 100.0% 38.2%
3199378 6088.1.1.1 ↗ alpha arrays › Helical bundle domain in elongation factor 3A › Helical bundle domain in elongation factor 3A › Helical bundle domain in elongation factor 3A › 4HB 0.58 47.0 4.04e-01 98.0% 83.3%
4887646 4030.1.1.2 ↗ alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › F-actin_cap_A 0.57 44.0 4.34e-01 100.0% 80.4%
5005176 604.15.1.0 ↗ alpha bundles › Spectrin repeat-like › Efb C-domain-like › Efb C-domain-like 0.57 44.0 4.12e-01 88.2% 76.9%
3224502 101.1.1.75 ↗ alpha arrays › HTH › HTH › Three-helical HTH › HTH_48 0.56 44.0 4.36e-01 100.0% 85.5%
4968998 7000.1.1.0 ↗ alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS 0.54 45.0 4.38e-01 100.0% 88.3%
4994857 101.1.2.932 ↗ alpha arrays › HTH › HTH › winged helix domain › wHTH-PRTase_assc 0.53 44.0 4.11e-01 100.0% 98.6%
D3 medium residues 332-469
PDB
Domain cluster: rep: MN062720.1__QDP45567.1__SEA_FUZZBUSTER_83__00083__D568-722_747-764
Pfam (3)
AccessionNameScoreE-valueQ covHMM cov
PF01057.24 best Parvo_NS1 211.1 2.20e-62 100.0% 50.5%
PF00519.24 PPV_E1_C 34.4 1.90e-08 96.4% 36.3%
PF19263.6 DUF5906 27.8 4.80e-06 77.5% 91.1%