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NendoU
Euk-VirRousettus_bat_coronavirus_HKU9
NendoU__YP_009924396__Rousettus_bat_coronavirus_HKU9__694006
Identity
- Accession:
- YP_009924396 ↗
- Protein ID:
- NendoU
- Kingdom:
- euk
Quality
95.2
mean pLDDT
Taxonomy
Orthornavirae›
Pisuviricota›
Pisoniviricetes›
Nidovirales›
Coronaviridae›
Betacoronavirus›
Rousettus_bat_coronavirus_HKU9
TaxID: 694006
Cluster
View cluster (23 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 2-60
Domain cluster:
rep: putative_coronavirus_nsp12__NP_839968__Porcine_epidemic_diarrhea_virus__28295__D1-51
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF19219.6 best | CoV_NSP15_N | 109.2 | 1.20e-31 | 100.0% | 96.7% |
D2
high
residues 69-180
Domain cluster:
rep: NSP15__YP_001941188__Turkey_coronavirus__11152__D65-176
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF19216.6 best | CoV_NSP15_M | 141.4 | 2.20e-41 | 98.2% | 93.2% |
D3
medium
residues 186-285
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF19215.6 best | CoV_NSP15_C | 115.1 | 4.10e-33 | 100.0% | 66.2% |
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2hw6A01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.64 | 29.0 | 3.13e-01 | 77.0% | 46.6% |
| 3f7wA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.62 | 30.0 | 3.17e-01 | 95.0% | 49.5% |
| 4r80A00 | 3.10.450.630 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.57 | 32.0 | 3.53e-01 | 98.0% | 69.7% |
| 5kvsA02 | 3.30.360.10 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 | 0.54 | 39.0 | 3.31e-01 | 75.0% | 50.0% |
| 5ighA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.53 | 28.0 | 2.94e-01 | 95.0% | 53.4% |
| 5evhA00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.52 | 42.0 | 3.97e-01 | 99.0% | 72.7% |
| 2bzgA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.51 | 45.0 | 3.50e-01 | 100.0% | 47.6% |
| 1nycA00 | 2.40.310.10 | Mainly Beta › Beta Barrel › Staphostatins › beta-Barrel protease inhibitors | 0.50 | 31.0 | 3.02e-01 | 96.0% | 54.1% |
| 2zw5A02 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.50 | 37.0 | 3.58e-01 | 80.0% | 82.4% |
ECOD (17)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2755815 | 372.2.1.2 ↗ | a+b complex topology › RNase A-like › EndoU-like › EndoU-like › CoV_NSP15_C | 0.97 | 94.0 | 7.75e-01 | 100.0% | 64.6% |
| 2623965 | 372.2.1.0 ↗ | a+b complex topology › RNase A-like › EndoU-like › EndoU-like | 0.96 | 93.0 | 7.71e-01 | 100.0% | 64.6% |
| 3513367 | 372.2.1.1 ↗ | a+b complex topology › RNase A-like › EndoU-like › EndoU-like › XendoU | 0.79 | 73.0 | 5.18e-01 | 100.0% | 72.6% |
| 3510572 | 372.2.1.1 ↗ | a+b complex topology › RNase A-like › EndoU-like › EndoU-like › XendoU | 0.79 | 73.0 | 5.25e-01 | 100.0% | 74.7% |
| 3505573 | 372.2.1.1 ↗ | a+b complex topology › RNase A-like › EndoU-like › EndoU-like › XendoU | 0.79 | 73.0 | 5.26e-01 | 100.0% | 74.0% |
| 3512494 | 372.2.1.1 ↗ | a+b complex topology › RNase A-like › EndoU-like › EndoU-like › XendoU | 0.79 | 72.0 | 5.25e-01 | 100.0% | 74.3% |
| 3922387 | 260.1.1.1 ↗ | a+b duplicates or obligate multimers › beta-hairpin-alpha-hairpin repeat › beta-hairpin-alpha-hairpin repeat › beta-hairpin-alpha-hairpin repeat › Plectin | 0.60 | 42.0 | 2.69e-01 | 73.0% | 28.7% |
| 3742121 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.59 | 25.0 | 3.70e-01 | 93.0% | 95.0% |
| 5072132 | 331.10.2.0 ↗ | a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase | 0.57 | 30.0 | 3.28e-01 | 99.0% | 61.3% |
| 3801966 | 252.1.1.2 ↗ | a+b two layers › DNA-binding domain › Methyl-CpG-binding domain, MBD › Methyl-CpG-binding domain, MBD › DUF7028 | 0.56 | 36.0 | 4.00e-01 | 93.0% | 85.3% |
| 3907024 | 260.1.1.1 ↗ | a+b duplicates or obligate multimers › beta-hairpin-alpha-hairpin repeat › beta-hairpin-alpha-hairpin repeat › beta-hairpin-alpha-hairpin repeat › Plectin | 0.55 | 39.0 | 2.82e-01 | 74.0% | 53.4% |
| 3280401 | 243.3.1.3 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › PepSY | 0.55 | 30.0 | 3.50e-01 | 98.0% | 78.5% |
| 5053933 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.54 | 28.0 | 3.38e-01 | 96.0% | 75.4% |
| 3716952 | 2007.2.3.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II | 0.53 | 41.0 | 2.86e-01 | 88.0% | 72.8% |
| 3321720 | 320.1.1.1 ↗ | a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H | 0.53 | 37.0 | 3.60e-01 | 72.0% | 77.3% |
| 3247128 | 2484.1.1.190 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › FBA_2 | 0.51 | 36.0 | 2.77e-01 | 75.0% | 37.6% |
| 4873705 | 71.1.1.2 ↗ | beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › LolA | 0.50 | 43.0 | 3.97e-01 | 95.0% | 92.3% |
D4
medium
residues 286-337
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF19215.6 best | CoV_NSP15_C | 64.3 | 1.80e-17 | 96.2% | 32.5% |
CATH (44)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1tm0A01 | 3.10.310.10 | Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 | 0.75 | 62.0 | 4.38e-01 | 94.2% | 76.8% |
| 6j7cA01 | 3.10.310.10 | Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 | 0.71 | 58.0 | 4.13e-01 | 94.2% | 74.7% |
| 3dlaB01 | 3.60.110.10 | Alpha Beta › 4-Layer Sandwich › Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase › Carbon-nitrogen hydrolase | 0.70 | 49.0 | 3.00e-01 | 75.0% | 15.5% |
| 1qy9A02 | 3.10.310.10 | Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 | 0.69 | 57.0 | 4.12e-01 | 96.2% | 76.1% |
| 2pbfA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.68 | 51.0 | 3.35e-01 | 80.8% | 20.2% |
| 1k8kA04 | 3.90.640.10 | Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 | 0.67 | 50.0 | 4.26e-01 | 84.6% | 70.7% |
| 2jheA02 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.66 | 56.0 | 4.52e-01 | 100.0% | 67.6% |
| 3ilvA01 | 3.60.110.10 | Alpha Beta › 4-Layer Sandwich › Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase › Carbon-nitrogen hydrolase | 0.66 | 49.0 | 3.14e-01 | 80.8% | 26.1% |
| 1tkjA00 | 3.40.630.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases | 0.66 | 53.0 | 3.46e-01 | 96.2% | 45.1% |
| 1zhhB01 | 3.30.450.220 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › LuxQ periplasmic domain, N-terminal subdomain | 0.65 | 53.0 | 3.93e-01 | 100.0% | 39.5% |
| 4dm5A00 | 3.30.1450.10 | Alpha Beta › 2-Layer Sandwich › Beta-lactamase Inhibitory Protein; Chain:B, domain 1 › | 0.65 | 54.0 | 4.68e-01 | 98.1% | 83.9% |
| 5jozB02 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.63 | 47.0 | 3.17e-01 | 80.8% | 39.2% |
| 3k8uA01 | 3.90.70.10 | Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases | 0.63 | 45.0 | 3.39e-01 | 76.9% | 34.4% |
| 1s4uX00 | 2.130.10.10 | Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase | 0.63 | 47.0 | 2.87e-01 | 82.7% | 17.1% |
| 3hi2B00 | 3.30.2310.40 | Alpha Beta › 2-Layer Sandwich › YaeB-like fold › | 0.63 | 52.0 | 4.36e-01 | 98.1% | 68.0% |
| 2retA00 | 3.30.1300.30 | Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › GSPII I/J protein-like | 0.62 | 52.0 | 4.60e-01 | 100.0% | 71.4% |
| 3wirA03 | 2.60.420.10 | Mainly Beta › Sandwich › Maltose phosphorylase, domain 3 › Maltose phosphorylase, domain 3 | 0.62 | 44.0 | 4.13e-01 | 96.2% | 59.4% |
| 3zsjA00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.62 | 42.0 | 3.17e-01 | 71.2% | 30.4% |
| 3holA03 | 2.40.128.240 | Mainly Beta › Beta Barrel › Lipocalin › | 0.61 | 51.0 | 4.39e-01 | 100.0% | 84.3% |
| 1ckmA01 | 3.30.470.30 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme | 0.60 | 50.0 | 3.70e-01 | 100.0% | 51.6% |
| 1bf5A04 | 3.30.505.10 | Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain | 0.59 | 44.0 | 3.65e-01 | 88.5% | 45.1% |
| 2oq1A03 | 3.30.505.10 | Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain | 0.59 | 42.0 | 3.57e-01 | 80.8% | 47.0% |
| 3dmgA02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.58 | 38.0 | 2.71e-01 | 71.2% | 30.9% |
| 4omfA00 | 1.10.645.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome-c3 Hydrogenase; chain B › Cytochrome-c3 Hydrogenase, chain B | 0.57 | 45.0 | 2.84e-01 | 100.0% | 75.8% |
| 3ms6A00 | 3.30.450.30 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic | 0.56 | 45.0 | 3.97e-01 | 100.0% | 78.9% |
| 1cc1L00 | 1.10.645.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome-c3 Hydrogenase; chain B › Cytochrome-c3 Hydrogenase, chain B | 0.56 | 48.0 | 2.82e-01 | 98.1% | 83.2% |
| 1e3dB00 | 1.10.645.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome-c3 Hydrogenase; chain B › Cytochrome-c3 Hydrogenase, chain B | 0.56 | 47.0 | 2.75e-01 | 98.1% | 83.2% |
| 1ggpA01 | 3.40.420.10 | Alpha Beta › 3-Layer(aba) Sandwich › Ricin (A subunit); domain 1 › Ricin (A subunit), domain 1 | 0.56 | 41.0 | 3.08e-01 | 82.7% | 41.6% |
| 4yg6B00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.55 | 45.0 | 3.28e-01 | 96.2% | 31.9% |
| 6l4lA02 | 3.10.310.10 | Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 | 0.55 | 43.0 | 3.42e-01 | 98.1% | 62.5% |
| 5wceA02 | 3.10.150.10 | Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 | 0.54 | 43.0 | 3.47e-01 | 100.0% | 79.8% |
| 2gu3A02 | 3.10.450.40 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.54 | 41.0 | 3.94e-01 | 86.5% | 84.1% |
| 2y1sA00 | 2.30.60.10 | Mainly Beta › Roll › HIV-inactivating Protein, Cyanovirin-n › Cyanovirin-N | 0.54 | 39.0 | 3.07e-01 | 76.9% | 97.2% |
| 1ksiA01 | 3.10.450.40 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.54 | 44.0 | 3.64e-01 | 92.3% | 70.8% |
| 4fh3A02 | 3.30.460.10 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 | 0.53 | 40.0 | 3.17e-01 | 86.5% | 89.6% |
| 3eayA02 | 3.30.310.130 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Ubiquitin-related | 0.53 | 40.0 | 3.17e-01 | 88.5% | 57.7% |
| 3w5mA06 | 2.60.420.10 | Mainly Beta › Sandwich › Maltose phosphorylase, domain 3 › Maltose phosphorylase, domain 3 | 0.53 | 40.0 | 3.37e-01 | 86.5% | 84.0% |
| 3oggA02 | 2.80.10.50 | Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) › | 0.52 | 35.0 | 2.55e-01 | 73.1% | 65.9% |
| 5b55A01 | 3.40.50.1100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.52 | 39.0 | 2.79e-01 | 88.5% | 50.5% |
| 1l1dA00 | 2.170.150.20 | Mainly Beta › Beta Complex › Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A › Peptide methionine sulfoxide reductase. | 0.51 | 41.0 | 3.06e-01 | 92.3% | 61.1% |
| 2qmiA02 | 2.40.128.210 | Mainly Beta › Beta Barrel › Lipocalin › Pab87 octamerisation domain | 0.51 | 40.0 | 3.37e-01 | 90.4% | 65.0% |
| 3loyA01 | 3.10.450.40 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.51 | 44.0 | 3.60e-01 | 100.0% | 70.3% |
| 3cm1A00 | 2.30.31.20 | Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Sporulation-specific cell division protein SsgB | 0.50 | 43.0 | 3.24e-01 | 100.0% | 69.1% |
| 2qm4A01 | 2.170.210.10 | Mainly Beta › Beta Complex › Dna Repair Protein Xrcc4; Chain: A, domain 1 › DNA double-strand break repair and VJ recombination XRCC4, N-terminal | 0.50 | 40.0 | 3.07e-01 | 96.2% | 76.2% |
ECOD (60)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2755815 | 372.2.1.2 ↗ | a+b complex topology › RNase A-like › EndoU-like › EndoU-like › CoV_NSP15_C | 0.97 | 93.0 | 6.26e-01 | 100.0% | 32.9% |
| 4078456 | 286.1.1.4 ↗ | a+b complex topology › Diaminopimelate epimerase-like › Diaminopimelate epimerase-like › Diaminopimelate epimerase-like › Pro_racemase | 0.77 | 65.0 | 4.67e-01 | 94.2% | 88.3% |
| 1115581 | 286.1.1.4 ↗ | a+b complex topology › Diaminopimelate epimerase-like › Diaminopimelate epimerase-like › Diaminopimelate epimerase-like › Pro_racemase | 0.74 | 61.0 | 4.39e-01 | 94.2% | 82.5% |
| 4137619 | 286.1.1.2 ↗ | a+b complex topology › Diaminopimelate epimerase-like › Diaminopimelate epimerase-like › Diaminopimelate epimerase-like › PhzC-PhzF | 0.73 | 60.0 | 4.53e-01 | 94.2% | 82.3% |
| 4044114 | 286.1.1.4 ↗ | a+b complex topology › Diaminopimelate epimerase-like › Diaminopimelate epimerase-like › Diaminopimelate epimerase-like › Pro_racemase | 0.73 | 60.0 | 4.26e-01 | 94.2% | 77.6% |
| 4935787 | 246.1.1.1 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › Carbon-nitrogen hydrolase › Carbon-nitrogen hydrolase › CN_hydrolase | 0.72 | 53.0 | 3.42e-01 | 80.8% | 20.0% |
| 4956278 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.71 | 55.0 | 5.60e-01 | 100.0% | 88.0% |
| 5041204 | 246.1.1.1 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › Carbon-nitrogen hydrolase › Carbon-nitrogen hydrolase › CN_hydrolase | 0.71 | 50.0 | 3.21e-01 | 75.0% | 20.0% |
| 4931451 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.70 | 59.0 | 4.76e-01 | 100.0% | 60.0% |
| 4980716 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.70 | 59.0 | 4.89e-01 | 100.0% | 69.0% |
| 4567826 | 246.1.1.1 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › Carbon-nitrogen hydrolase › Carbon-nitrogen hydrolase › CN_hydrolase | 0.68 | 51.0 | 3.27e-01 | 82.7% | 20.8% |
| 3970005 | 246.1.1.0 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › Carbon-nitrogen hydrolase › Carbon-nitrogen hydrolase | 0.68 | 51.0 | 3.24e-01 | 82.7% | 20.4% |
| 3213896 | 246.1.1.1 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › Carbon-nitrogen hydrolase › Carbon-nitrogen hydrolase › CN_hydrolase | 0.68 | 47.0 | 2.90e-01 | 75.0% | 15.5% |
| 3508353 | 2484.1.1.1 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 | 0.68 | 53.0 | 3.42e-01 | 88.5% | 62.0% |
| 4988948 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.67 | 55.0 | 4.42e-01 | 100.0% | 52.5% |
| 5025094 | 10.1.1.0 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases | 0.67 | 50.0 | 3.88e-01 | 80.8% | 40.9% |
| 3240647 | 3794.1.1.3 ↗ | a+b two layers › Methylcrotonyl-CoA carboxylase alpha-subunit BT domain-related › Methylcrotonyl-CoA carboxylase alpha-subunit BT domain-related › Barrel domain in methylcrotonyl-CoA carboxylase alpha-subunit › ACCA_BT | 0.66 | 55.0 | 4.24e-01 | 96.2% | 58.4% |
| 5017194 | 268.1.1.0 ↗ | a+b two layers › Sterol carrier protein-like › Sterol carrier protein, SCP-related › Sterol carrier protein, SCP-related | 0.66 | 55.0 | 4.43e-01 | 94.2% | 58.1% |
| 1260906 | 246.1.1.1 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › Carbon-nitrogen hydrolase › Carbon-nitrogen hydrolase › CN_hydrolase | 0.66 | 49.0 | 3.14e-01 | 80.8% | 26.2% |
| 5006332 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.66 | 55.0 | 4.83e-01 | 100.0% | 70.6% |
| 4945424 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.66 | 55.0 | 4.24e-01 | 100.0% | 43.8% |
| 4090669 | 60.1.2.1 ↗ | beta barrels › SPOC domain-like › SPOC domain-related › Ku70/80 subunit middle domain › Ku | 0.65 | 51.0 | 3.34e-01 | 88.5% | 65.7% |
| 3589620 | 4312.1.1.11 ↗ | a+b two layers › RelE-like › RelE-like › RelE-like › ParE-like_toxin | 0.65 | 53.0 | 4.62e-01 | 100.0% | 81.1% |
| 4459347 | 60.1.2.1 ↗ | beta barrels › SPOC domain-like › SPOC domain-related › Ku70/80 subunit middle domain › Ku | 0.65 | 52.0 | 3.39e-01 | 92.3% | 64.5% |
| 4184400 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.64 | 54.0 | 4.16e-01 | 100.0% | 45.4% |
| 3324772 | 243.5.1.1 ↗ | a+b two layers › Cystatin-like › Amine oxidase N-terminal region › Amine oxidase N-terminal region › Cu_amine_oxidN2 | 0.64 | 50.0 | 4.05e-01 | 84.6% | 75.8% |
| 4121524 | 304.125.1.1 ↗ | a+b two layers › Alpha-beta plaits › ferredoxin-like domain in Api92-like proteins › ferredoxin-like domain in Api92-like proteins › DUF1281_C | 0.64 | 47.0 | 3.58e-01 | 80.8% | 73.4% |
| 4459946 | 223.1.1.6 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains › dCache_1 | 0.64 | 53.0 | 3.49e-01 | 100.0% | 29.4% |
| 4606042 | 60.1.2.1 ↗ | beta barrels › SPOC domain-like › SPOC domain-related › Ku70/80 subunit middle domain › Ku | 0.64 | 49.0 | 3.22e-01 | 88.5% | 64.4% |
| 3510850 | 3459.1.1.0 ↗ | beta sandwiches › Fas apoptotic inhibitory molecule › Fas apoptotic inhibitory molecule › Fas apoptotic inhibitory molecule | 0.63 | 53.0 | 4.54e-01 | 100.0% | 81.1% |
| 4510810 | 60.1.2.1 ↗ | beta barrels › SPOC domain-like › SPOC domain-related › Ku70/80 subunit middle domain › Ku | 0.63 | 49.0 | 3.34e-01 | 92.3% | 72.0% |
| 3964389 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.63 | 51.0 | 4.38e-01 | 100.0% | 66.3% |
| 3615406 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.62 | 50.0 | 4.23e-01 | 100.0% | 78.0% |
| 3243571 | 286.1.1.2 ↗ | a+b complex topology › Diaminopimelate epimerase-like › Diaminopimelate epimerase-like › Diaminopimelate epimerase-like › PhzC-PhzF | 0.61 | 48.0 | 3.36e-01 | 90.4% | 30.5% |
| 3622643 | 4184.1.1.2 ↗ | beta barrels › MFPT repeat › MFPT repeat › MFPT repeat › MFP2b | 0.61 | 46.0 | 3.96e-01 | 82.7% | 58.8% |
| 3574976 | 4184.1.1.2 ↗ | beta barrels › MFPT repeat › MFPT repeat › MFPT repeat › MFP2b | 0.61 | 46.0 | 4.54e-01 | 82.7% | 89.1% |
| 3230771 | 4184.1.1.2 ↗ | beta barrels › MFPT repeat › MFPT repeat › MFPT repeat › MFP2b | 0.61 | 46.0 | 3.87e-01 | 82.7% | 55.6% |
| 3561689 | 223.1.1.71 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains › VGCC_alpha2 | 0.60 | 48.0 | 3.25e-01 | 100.0% | 29.2% |
| 5053147 | 2004.1.1.42 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE | 0.59 | 49.0 | 2.88e-01 | 98.1% | 34.7% |
| 4984579 | 2004.1.1.42 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE | 0.59 | 49.0 | 2.90e-01 | 98.1% | 36.6% |
| 4377336 | 2484.1.1.174 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › UvrC_RNaseH | 0.59 | 42.0 | 3.19e-01 | 78.8% | 31.9% |
| 4182548 | 244.4.1.0 ↗ | a+b two layers › FAD-linked reductases, C-terminal domain-like › Ni-Fe binding domain in nickel-iron hydrogenase large subunit › Ni-Fe binding domain in nickel-iron hydrogenase large subunit | 0.59 | 49.0 | 4.14e-01 | 100.0% | 96.8% |
| 4992459 | 4312.1.1.0 ↗ | a+b two layers › RelE-like › RelE-like › RelE-like | 0.58 | 48.0 | 4.49e-01 | 100.0% | 88.6% |
| 3964101 | 243.3.1.3 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › PepSY | 0.58 | 41.0 | 4.00e-01 | 76.9% | 86.7% |
| 2075292 | 3195.1.1.1 ↗ | extended segments › Mediator of RNA polymerase II transcription subunit 6 › Mediator of RNA polymerase II transcription subunit 6 › Mediator of RNA polymerase II transcription subunit 6 › Med6 | 0.58 | 40.0 | 3.02e-01 | 75.0% | 36.0% |
| 3764574 | 3338.2.1.1 ↗ | a+b two layers › Fragilysin-3 prodomain-like › Type II secretion chaperone CpaB › Type II secretion chaperone CpaB › Pep_M12B_propep | 0.56 | 43.0 | 3.26e-01 | 88.5% | 45.7% |
| 3334305 | 219.1.1.16 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 | 0.56 | 44.0 | 2.94e-01 | 94.2% | 28.6% |
| 3721100 | 4161.1.1.0 ↗ | beta complex topology › MOSC N-terminal domain-like › MOSC N-terminal domain-like › MOSC N-terminal domain-like | 0.55 | 47.0 | 2.94e-01 | 100.0% | 40.3% |
| 4069753 | 295.1.1.2 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › SsgA | 0.54 | 42.0 | 3.24e-01 | 90.4% | 48.1% |
| 5051418 | 295.1.1.0 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain | 0.52 | 40.0 | 3.09e-01 | 90.4% | 68.1% |
| 3886479 | 3338.2.1.1 ↗ | a+b two layers › Fragilysin-3 prodomain-like › Type II secretion chaperone CpaB › Type II secretion chaperone CpaB › Pep_M12B_propep | 0.52 | 41.0 | 3.22e-01 | 94.2% | 60.7% |
| 3496857 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.52 | 43.0 | 3.58e-01 | 100.0% | 82.9% |
| 5019887 | 243.3.1.3 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › PepSY | 0.52 | 40.0 | 3.74e-01 | 100.0% | 67.1% |
| 3573754 | 219.1.1.16 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 | 0.52 | 39.0 | 2.90e-01 | 90.4% | 36.4% |
| 4394739 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.52 | 39.0 | 3.70e-01 | 92.3% | 82.9% |
| 4243492 | 243.3.1.3 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › PepSY | 0.52 | 39.0 | 3.78e-01 | 84.6% | 91.7% |
| 3435691 | 211.1.1.0 ↗ | a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0.51 | 46.0 | 4.28e-01 | 100.0% | 93.8% |
| 4558617 | 12.6.1.3 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycoside hydrolase family 127 middle domain-related › Glycoside hydrolase family 127 middle domain-related › Bac_rhamnosid_C | 0.51 | 36.0 | 3.21e-01 | 78.8% | 48.8% |
| 185116 | 295.1.1.2 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › SsgA | 0.50 | 43.0 | 3.23e-01 | 100.0% | 68.6% |
| 3229102 | 207.1.1.81 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FTH | 0.50 | 40.0 | 2.72e-01 | 100.0% | 36.4% |