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OK041467.1__UDY80239.1__PAE2_14__00014
Bact-VirOK041467.1__UDY80239.1__PAE2_14__00014
Identity
- Accession:
- OK041467 ↗
- Kingdom:
- phage
Quality
71.2
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 39-95
D2
medium
residues 101-176
Domain cluster:
representative
CATH (45)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1quuA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.83 | 44.0 | 3.69e-01 | 100.0% | 31.7% |
| 2qffA00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.81 | 47.0 | 4.77e-01 | 100.0% | 59.5% |
| 3a98A02 | 1.20.1270.350 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain | 0.80 | 47.0 | 4.47e-01 | 100.0% | 51.7% |
| 3h0dB02 | 1.10.1200.150 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Transcriptional repressor of class III stress genes, C-terminal domain | 0.77 | 63.0 | 6.24e-01 | 90.8% | 93.8% |
| 1wgwA00 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.74 | 65.0 | 5.98e-01 | 98.7% | 84.8% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.71 | 64.0 | 5.62e-01 | 100.0% | 89.4% |
| 1ki1B01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.71 | 53.0 | 3.87e-01 | 78.9% | 58.3% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.71 | 63.0 | 5.26e-01 | 100.0% | 70.2% |
| 2ebzA02 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.67 | 57.0 | 5.65e-01 | 93.4% | 92.6% |
| 1vhnA02 | 1.10.1200.80 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Putative flavin oxidoreducatase; domain 2 | 0.67 | 52.0 | 5.38e-01 | 93.4% | 91.5% |
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.65 | 51.0 | 4.50e-01 | 84.2% | 97.3% |
| 2y44A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.65 | 45.0 | 3.44e-01 | 73.7% | 90.8% |
| 6z01B01 | 1.10.10.41 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Yeast DNA topoisomerase - domain 1 | 0.65 | 45.0 | 4.51e-01 | 96.1% | 71.8% |
| 2odmA00 | 1.10.287.750 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like | 0.64 | 48.0 | 4.78e-01 | 80.3% | 98.7% |
| 4xvxA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.64 | 43.0 | 3.51e-01 | 71.1% | 54.4% |
| 2n7zA00 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.64 | 48.0 | 4.32e-01 | 85.5% | 57.5% |
| 3c7jA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.63 | 53.0 | 4.34e-01 | 94.7% | 90.4% |
| 1xwmA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.63 | 45.0 | 3.21e-01 | 100.0% | 26.9% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.62 | 47.0 | 4.25e-01 | 82.9% | 98.2% |
| 1irxA05 | 1.10.10.350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.62 | 52.0 | 4.93e-01 | 96.1% | 87.1% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.62 | 48.0 | 4.16e-01 | 84.2% | 96.6% |
| 8a0rA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.61 | 48.0 | 4.10e-01 | 86.8% | 94.6% |
| 4rm7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.61 | 44.0 | 3.61e-01 | 76.3% | 60.4% |
| 2dbdA00 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.61 | 46.0 | 4.07e-01 | 81.6% | 57.0% |
| 3frrA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.61 | 44.0 | 3.33e-01 | 77.6% | 37.1% |
| 1ldjA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.60 | 47.0 | 4.11e-01 | 84.2% | 95.7% |
| 5gj7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.60 | 43.0 | 3.42e-01 | 75.0% | 58.9% |
| 2oocB00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.60 | 52.0 | 4.74e-01 | 100.0% | 74.3% |
| 4flbA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.60 | 41.0 | 3.45e-01 | 71.1% | 72.5% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.59 | 45.0 | 4.11e-01 | 82.9% | 89.6% |
| 7powA01 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.58 | 49.0 | 3.64e-01 | 94.7% | 67.7% |
| 2wy4A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.57 | 44.0 | 3.65e-01 | 84.2% | 87.8% |
| 2odvA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 37.0 | 3.29e-01 | 100.0% | 44.6% |
| 1bf5A01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.56 | 42.0 | 3.34e-01 | 82.9% | 78.6% |
| 3dkxA02 | 1.10.10.1480 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Plasmid replication protein | 0.56 | 39.0 | 4.14e-01 | 75.0% | 95.6% |
| 3amiA02 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.55 | 41.0 | 3.17e-01 | 82.9% | 81.9% |
| 1f2eA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.55 | 39.0 | 3.60e-01 | 76.3% | 74.5% |
| 2zt5A02 | 3.30.40.230 | Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › | 0.54 | 37.0 | 3.64e-01 | 73.7% | 72.6% |
| 3lssA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.54 | 47.0 | 4.10e-01 | 100.0% | 64.3% |
| 5kf6A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.52 | 44.0 | 3.14e-01 | 96.1% | 70.2% |
| 4irlB02 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.52 | 39.0 | 3.73e-01 | 85.5% | 68.8% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.51 | 44.0 | 4.24e-01 | 100.0% | 83.5% |
| 1uzcA00 | 1.10.10.440 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain | 0.50 | 35.0 | 3.67e-01 | 92.1% | 82.6% |
| 2ieqA00 | 1.20.5.300 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.50 | 45.0 | 4.28e-01 | 100.0% | 84.1% |
| 2pusA04 | 6.10.140.300 | Special › Helix non-globular › Helix Hairpins › | 0.50 | 41.0 | 3.65e-01 | 89.5% | 79.6% |
ECOD (34)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4455505 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.87 | 47.0 | 4.03e-01 | 100.0% | 35.7% |
| 3473545 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.83 | 44.0 | 3.47e-01 | 100.0% | 27.0% |
| 5060063 | 4133.1.1.0 ↗ | alpha arrays › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like | 0.70 | 49.0 | 5.11e-01 | 97.4% | 80.0% |
| 4992790 | 601.2.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes | 0.69 | 58.0 | 5.43e-01 | 94.7% | 91.6% |
| 3595289 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.68 | 59.0 | 5.53e-01 | 97.4% | 96.8% |
| 3306390 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.66 | 50.0 | 4.52e-01 | 81.6% | 81.0% |
| 4401282 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.66 | 51.0 | 4.36e-01 | 100.0% | 53.9% |
| 4107263 | 106.1.1.0 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like | 0.64 | 50.0 | 4.02e-01 | 84.2% | 80.0% |
| 3917447 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.63 | 48.0 | 3.90e-01 | 80.3% | 60.7% |
| 4013992 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.63 | 56.0 | 4.42e-01 | 100.0% | 86.3% |
| 3297600 | 621.1.1.7 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › EMC6 | 0.63 | 52.0 | 4.74e-01 | 90.8% | 85.0% |
| 3610581 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.63 | 54.0 | 4.57e-01 | 100.0% | 83.7% |
| 4939717 | 3758.2.1.1 ↗ | alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB | 0.63 | 48.0 | 3.60e-01 | 82.9% | 78.2% |
| 4986013 | 4994.1.1.0 ↗ | alpha duplicates or obligate multimers › EF2458-like › EF2458-like › EF2458-like | 0.62 | 48.0 | 4.64e-01 | 84.2% | 98.8% |
| 4592297 | 4040.1.1.3 ↗ | alpha bundles › Fic-like › Fic-like › Fic-like › AvrB_AvrC | 0.61 | 54.0 | 4.05e-01 | 100.0% | 67.4% |
| 3700264 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.61 | 52.0 | 4.48e-01 | 100.0% | 83.8% |
| 3997940 | 4133.1.1.1 ↗ | alpha arrays › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › ENT | 0.61 | 51.0 | 4.74e-01 | 92.1% | 88.4% |
| 3716233 | 601.18.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 | 0.60 | 51.0 | 4.32e-01 | 100.0% | 83.7% |
| 1206502 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.59 | 45.0 | 4.11e-01 | 82.9% | 89.6% |
| 3787792 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.58 | 43.0 | 4.06e-01 | 100.0% | 65.6% |
| 3932694 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.58 | 43.0 | 4.00e-01 | 80.3% | 95.0% |
| 4011300 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.58 | 44.0 | 4.26e-01 | 85.5% | 98.9% |
| 4011385 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 45.0 | 3.60e-01 | 88.2% | 71.9% |
| 4988301 | 3877.1.1.0 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC | 0.56 | 49.0 | 3.91e-01 | 96.1% | 92.7% |
| 5032064 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.56 | 44.0 | 4.37e-01 | 84.2% | 100.0% |
| 3475323 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.55 | 40.0 | 3.40e-01 | 78.9% | 69.6% |
| 3243709 | 603.1.1.97 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE | 0.55 | 49.0 | 3.50e-01 | 100.0% | 75.6% |
| 3661171 | 109.4.1.1254 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, E_motif | 0.53 | 46.0 | 2.77e-01 | 97.4% | 14.4% |
| 3606774 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.53 | 43.0 | 3.28e-01 | 100.0% | 39.4% |
| 3307768 | 174.1.1.2 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Jagunal | 0.53 | 50.0 | 3.72e-01 | 100.0% | 91.8% |
| 3968183 | 3758.2.1.1 ↗ | alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB | 0.53 | 41.0 | 3.29e-01 | 85.5% | 81.0% |
| 3262862 | 109.4.1.517 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Med24_N | 0.52 | 40.0 | 3.26e-01 | 84.2% | 43.4% |
| 5028733 | 3721.1.1.1 ↗ | alpha bundles › Protein regulator of cytokinesis 1 (PRC1) dimerization domain › Protein regulator of cytokinesis 1 (PRC1) dimerization domain › Protein regulator of cytokinesis 1 (PRC1) dimerization domain › VIT1 | 0.50 | 39.0 | 3.92e-01 | 97.4% | 85.3% |
| 4490114 | 5076.2.1.7 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › UPF0259 | 0.50 | 42.0 | 3.09e-01 | 98.7% | 45.4% |
D3
medium
residues 225-252
Domain cluster:
representative
CATH (38)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3purA02 | 2.60.120.650 | Mainly Beta › Sandwich › Jelly Rolls › Cupin | 0.84 | 66.0 | 3.75e-01 | 96.4% | 9.0% |
| 3kk4A01 | 1.10.3990.20 | Mainly Alpha › Orthogonal Bundle › Ribbon-helix-helix fold › protein bp1543 | 0.77 | 60.0 | 4.21e-01 | 100.0% | 27.5% |
| 3puaA01 | 2.60.120.650 | Mainly Beta › Sandwich › Jelly Rolls › Cupin | 0.77 | 59.0 | 3.41e-01 | 92.9% | 9.1% |
| 5axmB00 | 3.30.70.3000 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) | 0.76 | 54.0 | 3.16e-01 | 85.7% | 9.2% |
| 1aalB00 | 4.10.410.10 | Few Secondary Structures › Irregular › Factor Xa Inhibitor › Pancreatic trypsin inhibitor Kunitz domain | 0.71 | 56.0 | 4.51e-01 | 96.4% | 45.6% |
| 3i3lA02 | 3.30.390.160 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › | 0.69 | 56.0 | 3.69e-01 | 100.0% | 57.6% |
| 1pvgA01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.69 | 52.0 | 3.09e-01 | 89.3% | 74.2% |
| 2do3A01 | 2.30.30.30 | Mainly Beta › Roll › SH3 type barrels. › | 0.69 | 48.0 | 4.23e-01 | 82.1% | 45.1% |
| 1oi2A02 | 3.30.1180.20 | Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › Dihydroxyacetone kinase; domain 2 | 0.68 | 50.0 | 3.14e-01 | 85.7% | 13.6% |
| 5yvxA00 | 3.30.40.100 | Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › | 0.66 | 45.0 | 3.89e-01 | 82.1% | 38.3% |
| 3weeB03 | 3.90.640.10 | Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 | 0.66 | 53.0 | 3.70e-01 | 100.0% | 38.3% |
| 3venA02 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.65 | 47.0 | 2.83e-01 | 89.3% | 10.5% |
| 2iz4A02 | 2.20.25.590 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › | 0.64 | 45.0 | 4.24e-01 | 82.1% | 52.4% |
| 4bs9A04 | 3.30.40.250 | Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › | 0.63 | 51.0 | 3.67e-01 | 82.1% | 25.6% |
| 7uqyB01 | 3.90.550.10 | Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A | 0.63 | 44.0 | 2.68e-01 | 75.0% | 9.8% |
| 2ebnA00 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.61 | 46.0 | 2.68e-01 | 92.9% | 27.4% |
| 6eudA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.61 | 46.0 | 2.96e-01 | 96.4% | 32.4% |
| 1tocR02 | 4.10.410.10 | Few Secondary Structures › Irregular › Factor Xa Inhibitor › Pancreatic trypsin inhibitor Kunitz domain | 0.61 | 44.0 | 3.71e-01 | 85.7% | 41.4% |
| 3rhtA00 | 3.40.50.880 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain | 0.60 | 46.0 | 2.76e-01 | 100.0% | 41.3% |
| 1vw4H00 | 3.90.1180.10 | Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L13p; Chain: A; › Ribosomal protein L13 | 0.60 | 47.0 | 3.05e-01 | 100.0% | 19.6% |
| 6rwcA02 | 2.20.25.590 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › | 0.59 | 43.0 | 4.11e-01 | 71.4% | 51.3% |
| 2im9A02 | 2.30.260.10 | Mainly Beta › Roll › putative xylanase like fold › putative xylanase like domain | 0.58 | 40.0 | 2.78e-01 | 100.0% | 45.6% |
| 4bwxA03 | 1.10.287.3700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.57 | 41.0 | 3.20e-01 | 92.9% | 37.5% |
| 4ebrA00 | 3.30.1460.50 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.57 | 46.0 | 2.98e-01 | 100.0% | 41.4% |
| 1td6A02 | 3.30.1790.10 | Alpha Beta › 2-Layer Sandwich › hypothetical protein mp506/mpn330, domain 2 › hypothetical protein mp506/mpn330, domain 2 | 0.57 | 40.0 | 3.11e-01 | 100.0% | 30.4% |
| 3j7aV00 | 2.40.50.1000 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.57 | 39.0 | 2.63e-01 | 85.7% | 15.1% |
| 2ezvA02 | 2.40.50.610 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Type II restriction enzyme SfiI, DNA-recognition domain | 0.56 | 43.0 | 3.40e-01 | 92.9% | 77.1% |
| 2jx8A00 | 2.20.70.10 | Mainly Beta › Single Sheet › Ubiquitin Ligase Nedd4; Chain: W; › | 0.56 | 38.0 | 3.61e-01 | 85.7% | 51.1% |
| 7ejoB01 | 3.30.2260.10 | Alpha Beta › 2-Layer Sandwich › ERH-like fold › Enhancer of rudimentary | 0.55 | 42.0 | 3.30e-01 | 100.0% | 43.4% |
| 2r44A02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.55 | 41.0 | 2.64e-01 | 78.6% | 13.2% |
| 4obmA00 | 3.40.630.190 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › LCP protein | 0.55 | 40.0 | 2.40e-01 | 89.3% | 16.3% |
| 4l8nA03 | 3.30.160.670 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.54 | 40.0 | 2.57e-01 | 71.4% | 12.2% |
| 4c1sA00 | 1.50.10.20 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.54 | 37.0 | 2.16e-01 | 100.0% | 29.1% |
| 2y8yA02 | 3.30.70.1210 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Crispr-associated protein; domain 2 | 0.54 | 38.0 | 2.75e-01 | 92.9% | 80.9% |
| 4mb7A02 | 1.10.8.50 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.53 | 36.0 | 2.52e-01 | 100.0% | 17.0% |
| 2qrdE01 | 3.10.580.10 | Alpha Beta › Roll › CBS-domain › CBS-domain | 0.52 | 39.0 | 2.42e-01 | 71.4% | 73.9% |
| 2lxxA00 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.52 | 37.0 | 2.55e-01 | 100.0% | 53.9% |
| 2nmlA00 | 3.30.2260.10 | Alpha Beta › 2-Layer Sandwich › ERH-like fold › Enhancer of rudimentary | 0.52 | 38.0 | 2.89e-01 | 100.0% | 36.0% |
ECOD (56)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3707100 | 2004.1.1.364 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD+Helicase_C | 0.83 | 61.0 | 3.31e-01 | 85.7% | 4.4% |
| 3770311 | 109.4.1.154 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FA_FANCE | 0.82 | 65.0 | 3.62e-01 | 100.0% | 7.3% |
| 4987009 | 3837.1.1.1 ↗ | alpha bundles › Uncharacterized conserved protein Dip1984 › Uncharacterized conserved protein Dip1984 › Uncharacterized conserved protein Dip1984 › DUF6847 | 0.80 | 57.0 | 3.58e-01 | 100.0% | 14.7% |
| 3995122 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.79 | 56.0 | 3.25e-01 | 71.4% | 8.9% |
| 3735908 | 109.4.1.1588 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF27584, PF27595, PF30849 | 0.78 | 61.0 | 3.14e-01 | 89.3% | 13.8% |
| 4979113 | 620.1.1.6 ↗ | alpha bundles › YfiT-like putative metal-dependent hydrolases › YfiT-like putative metal-dependent hydrolases › YfiT-like putative metal-dependent hydrolases › DinB_2 | 0.74 | 57.0 | 3.66e-01 | 100.0% | 19.6% |
| 3208003 | 109.4.1.1685 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF27595, PF30849 | 0.73 | 54.0 | 2.91e-01 | 89.3% | 3.6% |
| 3217011 | 198.1.1.4 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › DUF3456 | 0.71 | 51.0 | 3.46e-01 | 85.7% | 19.2% |
| None | — | 0.71 | 52.0 | 2.90e-01 | 78.6% | 6.3% | |
| 3240202 | 384.1.1.0 ↗ | few secondary structure elements › BPTI-like › BPTI-like › BPTI-like | 0.70 | 54.0 | 3.71e-01 | 96.4% | 24.8% |
| 4030223 | 2004.1.1.418 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MCM, Mg_chelatase | 0.70 | 53.0 | 3.03e-01 | 85.7% | 11.9% |
| 3594046 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.69 | 53.0 | 3.07e-01 | 85.7% | 12.3% |
| 5065789 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.69 | 49.0 | 4.69e-01 | 92.9% | 60.0% |
| None | — | 0.69 | 53.0 | 3.01e-01 | 85.7% | 11.4% | |
| 3699463 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.67 | 48.0 | 2.87e-01 | 78.6% | 9.3% |
| 3718634 | 109.3.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 | 0.67 | 48.0 | 2.84e-01 | 82.1% | 14.3% |
| 4618205 | 604.1.1.150 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF28954 | 0.67 | 49.0 | 3.29e-01 | 75.0% | 17.5% |
| 3377628 | 2004.1.1.46 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MCM | 0.67 | 50.0 | 3.02e-01 | 85.7% | 16.8% |
| 1145958 | 2484.1.1.2 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin | 0.66 | 53.0 | 3.39e-01 | 100.0% | 25.0% |
| 3176989 | 601.19.1.40 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › PF28954 | 0.66 | 49.0 | 3.06e-01 | 75.0% | 13.1% |
| 3732352 | 601.39.1.4 ↗ | alpha bundles › Four-helical up-and-down bundle › Enhancer of filamentation 1 › Enhancer of filamentation 1 › DUF3433 | 0.66 | 49.0 | 3.03e-01 | 89.3% | 15.4% |
| 4943614 | 2004.1.1.155 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_3 | 0.65 | 49.0 | 2.93e-01 | 85.7% | 14.4% |
| 3934573 | 2485.1.1.3 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Glutaredoxin | 0.65 | 49.0 | 3.26e-01 | 89.3% | 28.8% |
| 3499106 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.65 | 49.0 | 2.79e-01 | 100.0% | 14.5% |
| 3472858 | 145.1.1.32 ↗ | alpha arrays › F-box domain › F-box domain › F-box domain › F-box_4 | 0.64 | 45.0 | 3.59e-01 | 85.7% | 30.1% |
| 3681670 | 2004.1.1.46 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MCM | 0.64 | 50.0 | 2.87e-01 | 85.7% | 9.5% |
| 3661784 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.63 | 52.0 | 2.97e-01 | 100.0% | 13.8% |
| 3811172 | 2004.1.1.418 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MCM, Mg_chelatase | 0.63 | 48.0 | 2.76e-01 | 85.7% | 11.0% |
| 3581438 | 4291.1.1.1 ↗ | beta barrels › Oxysterol-binding protein › Oxysterol-binding protein › Oxysterol-binding protein › Oxysterol_BP | 0.63 | 46.0 | 2.58e-01 | 71.4% | 5.5% |
| 3512515 | 247.1.1.45 ↗ | a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B, RMMBL, Lactamase_B_2 | 0.63 | 44.0 | 2.58e-01 | 85.7% | 11.7% |
| 3961108 | 2004.1.1.155 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_3 | 0.63 | 47.0 | 3.10e-01 | 85.7% | 23.8% |
| 3516174 | 5050.1.1.31 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › SLC52_ribofla_tr | 0.62 | 48.0 | 2.90e-01 | 85.7% | 9.8% |
| 3707395 | 2004.1.1.46 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MCM | 0.62 | 47.0 | 3.04e-01 | 85.7% | 22.9% |
| 3497680 | 5054.1.1.63 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans, YVC1_C | 0.62 | 49.0 | 2.82e-01 | 100.0% | 16.7% |
| 3284346 | 2004.1.1.155 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_3 | 0.62 | 46.0 | 2.75e-01 | 85.7% | 14.2% |
| 3814245 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.61 | 42.0 | 4.25e-01 | 89.3% | 88.6% |
| 3972249 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.61 | 45.0 | 2.77e-01 | 85.7% | 16.3% |
| 3706365 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.61 | 47.0 | 4.13e-01 | 96.4% | 76.0% |
| 4003785 | 5.1.3.2 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Ldl_recept_b | 0.60 | 49.0 | 2.85e-01 | 100.0% | 8.5% |
| 3447963 | 375.3.1.0 ↗ | few secondary structure elements › Rubredoxin-like › CSL zinc finger › CSL zinc finger | 0.59 | 43.0 | 3.67e-01 | 100.0% | 43.1% |
| 3490954 | 2005.1.1.54 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Diphthami_syn_2, PF28410 | 0.59 | 41.0 | 2.46e-01 | 89.3% | 8.8% |
| 3498497 | 301.7.1.0 ↗ | a+b three layers › Bacillus chorismate mutase-like › YjgF-like › YjgF-like | 0.58 | 41.0 | 2.60e-01 | 89.3% | 11.6% |
| 3465518 | 304.9.1.1 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 | 0.58 | 43.0 | 2.81e-01 | 71.4% | 13.8% |
| 3487793 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.58 | 42.0 | 2.45e-01 | 85.7% | 36.8% |
| 3989905 | 327.11.1.3 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) › KH_5 | 0.58 | 43.0 | 3.24e-01 | 85.7% | 28.9% |
| 3915628 | 5.1.4.12 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Sema | 0.57 | 41.0 | 2.33e-01 | 92.9% | 8.6% |
| 3577414 | 2485.1.1.40 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › GST_N_3 | 0.55 | 39.0 | 2.62e-01 | 89.3% | 24.0% |
| 1614408 | 2004.1.1.155 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_3 | 0.55 | 41.0 | 2.51e-01 | 78.6% | 10.0% |
| 4276892 | 7567.1.1.1 ↗ | a/b three-layered sandwiches › LmbE-like › LmbE-like › LmbE-like › PIG-L | 0.54 | 46.0 | 2.67e-01 | 96.4% | 8.5% |
| 3649913 | 5050.1.1.58 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › NFD4_C | 0.54 | 39.0 | 2.56e-01 | 96.4% | 14.7% |
| 3593736 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.54 | 40.0 | 2.89e-01 | 78.6% | 20.0% |
| 3533069 | 375.6.1.2 ↗ | few secondary structure elements › Rubredoxin-like › FlhC-like › FlhC-like › PF31275 | 0.52 | 38.0 | 3.78e-01 | 78.6% | 76.7% |
| 3332050 | 7523.1.1.4 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › SBP_bac_3 | 0.52 | 40.0 | 2.58e-01 | 71.4% | 12.5% |
| 3705742 | 375.1.1.7 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIS_C | 0.51 | 35.0 | 3.22e-01 | 100.0% | 75.9% |
| 4608282 | 2484.1.1.70 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › FtsA | 0.51 | 38.0 | 2.20e-01 | 100.0% | 8.1% |
| 3522640 | 386.1.1.248 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-C2H2_ZNF592 | 0.51 | 34.0 | 3.45e-01 | 89.3% | 74.3% |
D4
medium
residues 331-398
Domain cluster:
representative
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1v66A00 | 1.10.720.30 | Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › SAP domain | 0.67 | 46.0 | 4.72e-01 | 97.1% | 73.8% |
| 1bh9B00 | 1.10.20.10 | Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A | 0.64 | 45.0 | 4.12e-01 | 73.5% | 87.6% |
| 3dewA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.59 | 50.0 | 4.00e-01 | 95.6% | 76.4% |
| 4rflA02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.58 | 49.0 | 3.53e-01 | 95.6% | 100.0% |
| 1cpcA00 | 1.10.490.20 | Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins | 0.54 | 44.0 | 3.37e-01 | 100.0% | 37.7% |
| 1cw1A00 | 3.40.718.10 | Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase | 0.53 | 43.0 | 2.68e-01 | 91.2% | 89.9% |
| 1pu6A01 | 1.10.1670.10 | Mainly Alpha › Orthogonal Bundle › Endonuclease Iii, domain 2 › Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) | 0.52 | 38.0 | 3.53e-01 | 95.6% | 59.6% |
| 4dmvA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 39.0 | 3.69e-01 | 83.8% | 67.1% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4994061 | 601.7.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like | 0.69 | 51.0 | 4.01e-01 | 79.4% | 78.3% |
| 3822008 | 5069.1.3.93 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › Prolamin_like | 0.69 | 51.0 | 4.70e-01 | 80.9% | 85.6% |
| 5029691 | 601.7.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like | 0.67 | 50.0 | 4.02e-01 | 80.9% | 83.0% |
| 4483871 | 601.7.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › GlnD_UR_UTase | 0.63 | 46.0 | 3.59e-01 | 77.9% | 52.7% |
| 3483114 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.62 | 55.0 | 5.12e-01 | 98.5% | 100.0% |
| 3491641 | 192.5.1.0 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat | 0.61 | 54.0 | 5.06e-01 | 100.0% | 100.0% |
| 3961339 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.60 | 53.0 | 4.24e-01 | 98.5% | 73.3% |
| 3586355 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.59 | 52.0 | 3.32e-01 | 98.5% | 70.4% |
| 4176201 | 621.1.1.3 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB | 0.59 | 50.0 | 4.46e-01 | 92.6% | 69.5% |
| 3990863 | 101.1.10.1 ↗ | alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N | 0.58 | 44.0 | 3.35e-01 | 82.4% | 62.9% |
| 3718013 | 621.1.1.7 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › EMC6 | 0.56 | 46.0 | 4.18e-01 | 94.1% | 65.3% |
| 5078378 | 601.7.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like | 0.55 | 47.0 | 3.69e-01 | 94.1% | 66.9% |
| 5001143 | 601.7.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like | 0.51 | 46.0 | 3.59e-01 | 100.0% | 57.9% |
D5
medium
residues 399-491
Domain cluster:
representative
CATH (29)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3if8B02 | 1.20.58.730 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.75 | 44.0 | 4.36e-01 | 90.3% | 55.0% |
| 1sqpF00 | 1.10.1090.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome Bc1 Complex; Chain F › Cytochrome b-c1 complex subunit 7 | 0.71 | 40.0 | 3.84e-01 | 84.9% | 48.6% |
| 4oo2A02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.66 | 50.0 | 3.81e-01 | 78.5% | 96.1% |
| 5zw7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.65 | 49.0 | 4.11e-01 | 78.5% | 95.4% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.60 | 44.0 | 4.04e-01 | 76.3% | 59.8% |
| 1u00A02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.59 | 44.0 | 4.39e-01 | 97.8% | 76.0% |
| 3ddhA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.57 | 37.0 | 3.91e-01 | 84.9% | 75.3% |
| 1dkxA02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.57 | 44.0 | 4.71e-01 | 98.9% | 95.0% |
| 1zylA03 | 1.20.1270.170 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.57 | 38.0 | 3.73e-01 | 87.1% | 62.1% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.55 | 33.0 | 3.30e-01 | 71.0% | 56.0% |
| 5jfqB00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.55 | 45.0 | 3.17e-01 | 96.8% | 27.1% |
| 3gi7A00 | 1.20.1270.180 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.55 | 50.0 | 4.89e-01 | 100.0% | 90.3% |
| 1nzeA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.54 | 41.0 | 3.89e-01 | 93.5% | 67.9% |
| 6o7uc01 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.54 | 48.0 | 3.79e-01 | 97.8% | 58.4% |
| 3rguB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.54 | 40.0 | 4.16e-01 | 89.2% | 82.8% |
| 2o7gA00 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.54 | 37.0 | 3.86e-01 | 92.5% | 76.1% |
| 1st6A04 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.54 | 44.0 | 4.14e-01 | 94.6% | 72.6% |
| 3eo8A00 | 3.40.109.10 | Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase | 0.54 | 46.0 | 3.59e-01 | 97.8% | 67.1% |
| 2hroA02 | 1.10.274.10 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain | 0.53 | 47.0 | 4.21e-01 | 98.9% | 82.0% |
| 4i0xH00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.53 | 37.0 | 4.11e-01 | 73.1% | 97.4% |
| 5axmB00 | 3.30.70.3000 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) | 0.52 | 43.0 | 3.22e-01 | 90.3% | 43.9% |
| 3zciA00 | 1.20.58.1660 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 47.0 | 3.71e-01 | 100.0% | 77.5% |
| 1t98A02 | 1.20.58.590 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain | 0.52 | 46.0 | 3.84e-01 | 97.8% | 71.2% |
| 2bl2A00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.52 | 45.0 | 3.84e-01 | 98.9% | 78.8% |
| 2pkeA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.52 | 33.0 | 3.58e-01 | 87.1% | 78.2% |
| 1or7B01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.51 | 37.0 | 3.70e-01 | 90.3% | 75.5% |
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.50 | 45.0 | 4.33e-01 | 97.8% | 96.2% |
| 2etdA00 | 1.20.1440.20 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain | 0.50 | 42.0 | 3.69e-01 | 92.5% | 100.0% |
| 2pmsC00 | 6.10.140.920 | Special › Helix non-globular › Helix Hairpins › | 0.50 | 39.0 | 3.75e-01 | 82.8% | 89.9% |
ECOD (20)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4980095 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.62 | 43.0 | 4.13e-01 | 76.3% | 61.9% |
| 4965736 | 3843.1.1.33 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Vut_1 | 0.59 | 47.0 | 4.54e-01 | 87.1% | 80.0% |
| 4026470 | 3871.1.1.1 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN | 0.58 | 52.0 | 4.38e-01 | 97.8% | 66.7% |
| 4027257 | 3871.1.1.1 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN | 0.58 | 51.0 | 4.39e-01 | 97.8% | 72.4% |
| 3242888 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.57 | 51.0 | 4.52e-01 | 100.0% | 79.3% |
| 3956423 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.55 | 47.0 | 4.39e-01 | 92.5% | 100.0% |
| 3471232 | 7552.1.1.1 ↗ | a/b three-layered sandwiches › Amidase signature (AS) enzymes › Amidase signature (AS) enzymes › Amidase signature (AS) enzymes › Amidase | 0.55 | 46.0 | 2.90e-01 | 95.7% | 36.8% |
| 4974533 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.54 | 39.0 | 3.44e-01 | 76.3% | 60.7% |
| 4544758 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.54 | 45.0 | 4.26e-01 | 92.5% | 90.9% |
| 3912641 | 1203.1.2.1 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ASD2 | 0.53 | 45.0 | 3.42e-01 | 96.8% | 68.2% |
| 3499111 | 632.1.1.3 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Alpha-mann_mid | 0.53 | 43.0 | 3.78e-01 | 87.1% | 60.0% |
| 3586382 | 601.1.2.4 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_R4 | 0.52 | 40.0 | 4.00e-01 | 84.9% | 79.0% |
| 3514718 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.52 | 45.0 | 4.19e-01 | 96.8% | 89.6% |
| 3244597 | 5001.1.1.84 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srz | 0.51 | 46.0 | 3.21e-01 | 100.0% | 46.3% |
| 3628755 | 109.4.1.1493 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Zw10_middle, ZW10_C, ZW10_C2 | 0.51 | 46.0 | 2.69e-01 | 97.8% | 13.2% |
| 3272245 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.51 | 46.0 | 3.29e-01 | 98.9% | 39.3% |
| 3733397 | 109.42.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › E3 ubiquitin-protein ligase SHPRH first helical domain › E3 ubiquitin-protein ligase SHPRH first helical domain | 0.50 | 45.0 | 3.58e-01 | 98.9% | 53.7% |
| 3783600 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.50 | 38.0 | 3.55e-01 | 77.4% | 75.5% |
| 4814 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.50 | 36.0 | 3.45e-01 | 90.3% | 62.8% |
| 5069594 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.50 | 42.0 | 3.33e-01 | 96.8% | 42.5% |