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OM868076.1__UPT53056.1__X__00022
Bact-VirOM868076.1__UPT53056.1__X__00022
Identity
- Accession:
- OM868076 ↗
- Kingdom:
- phage
Quality
68.5
mean pLDDT
Taxonomy
TaxID: 2928847
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 370-504
Domain cluster:
representative
CATH (80)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2b5uA02 | 1.10.287.620 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins | 0.89 | 66.0 | 6.18e-01 | 76.3% | 81.4% |
| 5j1gA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.89 | 71.0 | 5.76e-01 | 100.0% | 48.7% |
| 3uumA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.88 | 67.0 | 7.04e-01 | 100.0% | 86.9% |
| 3qo8A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.87 | 52.0 | 5.86e-01 | 71.9% | 76.4% |
| 3u0cA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.85 | 63.0 | 6.03e-01 | 75.6% | 70.2% |
| 3g67A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.85 | 63.0 | 5.26e-01 | 75.6% | 89.7% |
| 6h2dS01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.85 | 76.0 | 6.32e-01 | 94.8% | 74.9% |
| 2ch7A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.85 | 62.0 | 4.64e-01 | 75.6% | 39.8% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.84 | 62.0 | 5.03e-01 | 75.6% | 44.3% |
| 1u5pA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.84 | 62.0 | 6.88e-01 | 100.0% | 94.4% |
| 3lssA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.84 | 48.0 | 5.27e-01 | 74.8% | 68.8% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.84 | 60.0 | 6.73e-01 | 100.0% | 93.5% |
| 1s35A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.83 | 63.0 | 6.88e-01 | 100.0% | 95.5% |
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.83 | 59.0 | 6.78e-01 | 100.0% | 100.0% |
| 6grjB01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.82 | 74.0 | 5.55e-01 | 96.3% | 75.6% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.82 | 59.0 | 6.33e-01 | 100.0% | 85.5% |
| 4mt4A00 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.82 | 64.0 | 4.24e-01 | 80.7% | 87.5% |
| 4k1pE00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.81 | 75.0 | 5.55e-01 | 100.0% | 73.2% |
| 2nrjA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.80 | 74.0 | 5.51e-01 | 100.0% | 64.8% |
| 5nl6B01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.80 | 63.0 | 6.67e-01 | 100.0% | 91.7% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.80 | 61.0 | 5.40e-01 | 98.5% | 56.2% |
| 3ofnY00 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.80 | 56.0 | 6.04e-01 | 78.5% | 83.5% |
| 3ck6C02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.79 | 59.0 | 6.30e-01 | 100.0% | 88.2% |
| 3eabE00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.79 | 50.0 | 6.07e-01 | 97.0% | 100.0% |
| 7p3rA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.79 | 73.0 | 5.41e-01 | 100.0% | 80.3% |
| 1wcrA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.78 | 55.0 | 6.23e-01 | 99.3% | 94.2% |
| 1x04A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.78 | 57.0 | 4.94e-01 | 74.8% | 53.5% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.78 | 51.0 | 5.03e-01 | 100.0% | 62.2% |
| 3rkgA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.78 | 68.0 | 6.29e-01 | 100.0% | 75.0% |
| 1wp1B01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.78 | 58.0 | 4.11e-01 | 76.3% | 40.2% |
| 3vkgA12 | 1.10.287.2610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.78 | 57.0 | 4.81e-01 | 75.6% | 73.0% |
| 1wdzA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.78 | 57.0 | 4.73e-01 | 76.3% | 45.0% |
| 4e40A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.77 | 57.0 | 4.59e-01 | 75.6% | 41.6% |
| 3syvA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.77 | 54.0 | 4.37e-01 | 71.1% | 42.0% |
| 3l39A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.77 | 57.0 | 4.99e-01 | 99.3% | 52.0% |
| 6w08A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.77 | 72.0 | 5.22e-01 | 100.0% | 71.1% |
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.77 | 57.0 | 6.40e-01 | 99.3% | 100.0% |
| 1qu7A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.77 | 56.0 | 4.65e-01 | 74.8% | 72.7% |
| 2efkA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.77 | 55.0 | 4.36e-01 | 74.1% | 38.2% |
| 1yc9A01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.75 | 56.0 | 4.15e-01 | 77.0% | 41.0% |
| 1wleA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.75 | 51.0 | 5.56e-01 | 71.9% | 82.5% |
| 2gl2B00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.74 | 54.0 | 6.01e-01 | 75.6% | 98.2% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.74 | 51.0 | 5.37e-01 | 100.0% | 78.3% |
| 3cazB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.74 | 51.0 | 4.42e-01 | 71.9% | 45.7% |
| 2q12A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.74 | 56.0 | 4.60e-01 | 79.3% | 47.9% |
| 3qweA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.74 | 56.0 | 4.47e-01 | 79.3% | 78.1% |
| 3ok8A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.73 | 53.0 | 4.54e-01 | 75.6% | 47.5% |
| 1a7mA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.73 | 41.0 | 3.66e-01 | 85.9% | 40.6% |
| 7aalA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.73 | 55.0 | 4.38e-01 | 79.3% | 42.1% |
| 5azpB01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.73 | 57.0 | 4.12e-01 | 83.0% | 68.0% |
| 2ficB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.72 | 52.0 | 4.51e-01 | 74.8% | 49.3% |
| 4hz4A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.72 | 47.0 | 5.10e-01 | 97.0% | 78.6% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 65.0 | 6.02e-01 | 100.0% | 76.9% |
| 1h7cA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 52.0 | 5.92e-01 | 88.9% | 100.0% |
| 1qoyA00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.71 | 65.0 | 4.97e-01 | 100.0% | 63.0% |
| 4f4cA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.70 | 60.0 | 3.80e-01 | 93.3% | 85.4% |
| 1u7lA02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.69 | 49.0 | 4.43e-01 | 78.5% | 54.1% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.69 | 39.0 | 4.41e-01 | 96.3% | 72.5% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.69 | 47.0 | 4.74e-01 | 97.8% | 68.6% |
| 6iknD01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.69 | 51.0 | 4.01e-01 | 76.3% | 42.7% |
| 3rx6A00 | 1.20.58.1090 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phage polarity suppression protein monomer | 0.68 | 60.0 | 5.30e-01 | 93.3% | 87.2% |
| 4dciA00 | 6.10.140.1110 | Special › Helix non-globular › Helix Hairpins › | 0.68 | 46.0 | 4.46e-01 | 81.5% | 62.6% |
| 1qdbA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.68 | 43.0 | 4.25e-01 | 76.3% | 59.4% |
| 4q4hB01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.67 | 57.0 | 4.21e-01 | 89.6% | 39.2% |
| 4p79A00 | 1.20.140.150 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.67 | 53.0 | 4.84e-01 | 100.0% | 63.0% |
| 2fupA00 | 1.20.58.300 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like | 0.65 | 52.0 | 5.33e-01 | 100.0% | 89.0% |
| 4lunU00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.65 | 55.0 | 4.16e-01 | 90.4% | 56.3% |
| 4qgpB00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.64 | 36.0 | 4.01e-01 | 85.9% | 69.2% |
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.64 | 49.0 | 5.30e-01 | 100.0% | 99.1% |
| 3rrkA02 | 1.20.1460.20 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › | 0.63 | 44.0 | 4.18e-01 | 77.8% | 61.3% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.63 | 52.0 | 5.27e-01 | 100.0% | 91.7% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.63 | 50.0 | 5.34e-01 | 100.0% | 99.1% |
| 1fntc01 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.62 | 51.0 | 4.54e-01 | 100.0% | 61.7% |
| 2v0xA01 | 1.10.287.3160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.62 | 54.0 | 5.07e-01 | 97.0% | 76.2% |
| 4kvmA02 | 1.25.40.1010 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.60 | 50.0 | 4.31e-01 | 90.4% | 71.3% |
| 2p61A00 | 1.20.120.490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain | 0.59 | 43.0 | 4.71e-01 | 100.0% | 89.5% |
| 4i17A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.55 | 46.0 | 3.88e-01 | 96.3% | 53.6% |
| 6xxvC00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.55 | 42.0 | 4.63e-01 | 99.3% | 99.1% |
| 3jrtA00 | 1.20.120.1060 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.51 | 45.0 | 4.22e-01 | 100.0% | 77.1% |
| 4bemJ00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.50 | 40.0 | 3.59e-01 | 97.8% | 61.9% |
ECOD (93)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4516566 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.89 | 66.0 | 5.76e-01 | 75.6% | 58.9% |
| 4013484 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.87 | 76.0 | 6.51e-01 | 100.0% | 60.5% |
| 4645599 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.87 | 64.0 | 4.57e-01 | 75.6% | 31.5% |
| 3598167 | 3755.1.1.0 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related | 0.86 | 61.0 | 5.86e-01 | 71.9% | 66.0% |
| 3694833 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.86 | 63.0 | 6.47e-01 | 75.6% | 83.8% |
| 3964486 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.86 | 63.0 | 5.88e-01 | 74.8% | 70.6% |
| 4219808 | 192.1.1.0 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain | 0.86 | 63.0 | 4.50e-01 | 75.6% | 31.0% |
| 1877523 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.85 | 68.0 | 7.44e-01 | 97.8% | 100.0% |
| 3730423 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.85 | 62.0 | 4.52e-01 | 74.1% | 77.5% |
| 4955963 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.85 | 63.0 | 5.38e-01 | 75.6% | 83.0% |
| 3944731 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.85 | 60.0 | 5.53e-01 | 71.9% | 59.4% |
| 5032512 | 5086.1.1.234 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › CdvA | 0.84 | 74.0 | 7.43e-01 | 91.9% | 100.0% |
| 3852268 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.84 | 61.0 | 5.68e-01 | 74.8% | 64.4% |
| 5007124 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.84 | 61.0 | 4.67e-01 | 75.6% | 37.9% |
| 1759951 | 5086.1.1.88 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_CyaD | 0.83 | 59.0 | 5.17e-01 | 74.8% | 51.0% |
| 5060432 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.83 | 61.0 | 6.21e-01 | 74.8% | 77.7% |
| 4549103 | 3755.4.1.54 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PF30340 | 0.83 | 61.0 | 4.29e-01 | 75.6% | 68.7% |
| 5045101 | 4121.1.1.19 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › PF27230 | 0.83 | 74.0 | 5.38e-01 | 100.0% | 37.1% |
| 3190705 | 2004.1.1.433 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23 | 0.83 | 64.0 | 4.02e-01 | 79.3% | 51.4% |
| 3486831 | 220.1.1.22 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › FERM_C | 0.83 | 60.0 | 4.79e-01 | 74.1% | 42.4% |
| 3834430 | 3755.3.1.285 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › NET2A | 0.82 | 61.0 | 5.27e-01 | 76.3% | 52.0% |
| 3838987 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.82 | 59.0 | 5.12e-01 | 74.1% | 50.5% |
| 3718629 | 3755.2.1.0 ↗ | alpha bundles › YscO-like › Flagellar FliJ protein › Flagellar FliJ protein | 0.82 | 60.0 | 4.72e-01 | 74.8% | 39.6% |
| 3958574 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.82 | 64.0 | 5.97e-01 | 83.0% | 66.7% |
| 3615269 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.82 | 77.0 | 6.51e-01 | 100.0% | 79.5% |
| 3235363 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.82 | 61.0 | 5.05e-01 | 76.3% | 46.8% |
| 3604134 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.82 | 76.0 | 6.93e-01 | 100.0% | 81.7% |
| 3631949 | 309.1.2.5 ↗ | a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › ThrRS/AlaRS editing domain › Seryl_tRNA_N | 0.82 | 59.0 | 6.18e-01 | 74.8% | 83.2% |
| 4428524 | 2004.1.1.567 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23 | 0.81 | 60.0 | 3.63e-01 | 75.6% | 63.3% |
| 3711643 | 3939.1.1.0 ↗ | alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain | 0.81 | 59.0 | 4.64e-01 | 74.8% | 38.9% |
| 3961148 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.81 | 59.0 | 6.26e-01 | 74.8% | 85.0% |
| 3879381 | 603.2.1.1 ↗ | alpha bundles › STAT-like › STAT › STAT › STAT_alpha | 0.81 | 70.0 | 6.71e-01 | 100.0% | 80.6% |
| 3548233 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.81 | 67.0 | 6.25e-01 | 100.0% | 71.5% |
| 3952630 | 3755.1.1.0 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related | 0.80 | 59.0 | 5.87e-01 | 75.6% | 83.6% |
| 3061928 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.80 | 73.0 | 6.48e-01 | 100.0% | 69.8% |
| 3169381 | 874.1.1.0 ↗ | a+b duplicates or obligate multimers › Smc hinge domain › Smc hinge domain › Smc hinge domain | 0.80 | 58.0 | 5.02e-01 | 74.8% | 86.8% |
| 3622654 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.80 | 75.0 | 6.47e-01 | 100.0% | 72.0% |
| 4012748 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.80 | 72.0 | 5.38e-01 | 100.0% | 41.3% |
| 3341646 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.80 | 58.0 | 4.45e-01 | 74.8% | 92.4% |
| 3970271 | 3755.1.1.8 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › FliJ | 0.80 | 57.0 | 5.90e-01 | 74.8% | 78.4% |
| 4392204 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.80 | 58.0 | 4.89e-01 | 75.6% | 62.7% |
| 3911275 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.80 | 59.0 | 4.08e-01 | 76.3% | 33.4% |
| 5030936 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.79 | 58.0 | 5.05e-01 | 75.6% | 51.8% |
| 3793454 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.79 | 74.0 | 6.74e-01 | 100.0% | 78.3% |
| 3702176 | 603.1.1.100 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 | 0.79 | 66.0 | 6.58e-01 | 100.0% | 85.7% |
| 4569106 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.79 | 58.0 | 3.89e-01 | 75.6% | 61.7% |
| 3214390 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.79 | 56.0 | 5.59e-01 | 96.3% | 70.7% |
| 3621307 | 601.54.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › low CO2-inducible protein LCI1 › low CO2-inducible protein LCI1 | 0.79 | 71.0 | 6.63e-01 | 96.3% | 81.2% |
| 4320014 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.78 | 52.0 | 4.05e-01 | 71.9% | 33.3% |
| 3718312 | 604.1.1.118 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › GOSR1_N | 0.78 | 67.0 | 6.59e-01 | 100.0% | 84.8% |
| 5070736 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.78 | 56.0 | 4.83e-01 | 73.3% | 77.5% |
| 3719591 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.78 | 72.0 | 6.14e-01 | 100.0% | 77.2% |
| 3232199 | 4177.1.1.10 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH | 0.78 | 56.0 | 4.41e-01 | 74.1% | 39.3% |
| 3929613 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.78 | 55.0 | 4.13e-01 | 71.9% | 34.8% |
| 5007101 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.78 | 57.0 | 4.11e-01 | 75.6% | 28.6% |
| 3897356 | 603.1.1.17 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE | 0.78 | 69.0 | 5.93e-01 | 100.0% | 61.4% |
| 3263540 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.78 | 57.0 | 3.89e-01 | 75.6% | 64.7% |
| 3519973 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.78 | 56.0 | 4.49e-01 | 73.3% | 40.8% |
| 5064397 | 5086.1.1.231 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Rad50_zn_hook | 0.77 | 56.0 | 4.91e-01 | 74.8% | 96.4% |
| 2324029 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.77 | 50.0 | 5.26e-01 | 100.0% | 72.1% |
| 4014427 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.77 | 56.0 | 4.24e-01 | 74.8% | 35.7% |
| 3752375 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.77 | 71.0 | 6.22e-01 | 100.0% | 89.2% |
| 3213527 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.77 | 56.0 | 4.29e-01 | 74.8% | 36.1% |
| 3213281 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.76 | 53.0 | 4.17e-01 | 71.1% | 35.9% |
| 3688677 | 4121.1.1.7 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › PF26616 | 0.76 | 64.0 | 4.56e-01 | 100.0% | 31.4% |
| 3488631 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.76 | 55.0 | 4.31e-01 | 74.8% | 36.7% |
| 4018370 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.76 | 62.0 | 6.32e-01 | 95.6% | 89.2% |
| 4024356 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.76 | 70.0 | 6.61e-01 | 100.0% | 89.4% |
| 3701078 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.76 | 54.0 | 5.42e-01 | 100.0% | 72.6% |
| 3722750 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.76 | 70.0 | 5.22e-01 | 100.0% | 44.7% |
| 3576467 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.76 | 56.0 | 4.22e-01 | 76.3% | 35.7% |
| 3908810 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.75 | 56.0 | 4.25e-01 | 76.3% | 37.6% |
| 3768341 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.75 | 70.0 | 5.99e-01 | 98.5% | 77.6% |
| 3907844 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.75 | 69.0 | 6.13e-01 | 100.0% | 91.1% |
| 4344623 | 3758.2.1.1 ↗ | alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB | 0.75 | 68.0 | 5.86e-01 | 100.0% | 86.7% |
| 4029995 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.74 | 62.0 | 5.61e-01 | 100.0% | 66.1% |
| 3368299 | 4121.1.1.2 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › MRS2-like | 0.74 | 70.0 | 5.38e-01 | 100.0% | 69.6% |
| 3532355 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.74 | 54.0 | 4.07e-01 | 74.8% | 34.1% |
| 3551506 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.74 | 52.0 | 3.94e-01 | 71.1% | 34.3% |
| 3993135 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.74 | 68.0 | 5.97e-01 | 100.0% | 81.5% |
| 1291200 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.74 | 51.0 | 3.95e-01 | 71.1% | 35.9% |
| 3692987 | 3755.3.1.481 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PF30554 | 0.74 | 53.0 | 4.69e-01 | 74.1% | 94.2% |
| 4345467 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.73 | 56.0 | 3.77e-01 | 79.3% | 43.5% |
| 3242255 | 174.1.1.13 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF2700 | 0.72 | 53.0 | 5.08e-01 | 100.0% | 65.8% |
| 3477880 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.71 | 50.0 | 3.88e-01 | 71.9% | 36.9% |
| 4596031 | 109.4.1.3089 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MSP1_C | 0.71 | 65.0 | 4.85e-01 | 100.0% | 62.1% |
| 3398015 | 603.1.1.104 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › 7tm_7 | 0.70 | 64.0 | 4.65e-01 | 100.0% | 41.6% |
| 4941676 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.70 | 49.0 | 4.52e-01 | 75.6% | 56.0% |
| 3410076 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.69 | 51.0 | 3.97e-01 | 76.3% | 39.3% |
| 4026286 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.66 | 59.0 | 5.97e-01 | 99.3% | 98.5% |
| 3715005 | 604.8.1.0 ↗ | alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo | 0.65 | 59.0 | 5.59e-01 | 100.0% | 99.4% |
| 3490690 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.64 | 47.0 | 4.93e-01 | 99.3% | 83.2% |
| 3947112 | 192.8.1.394 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › MscS_porin | 0.59 | 52.0 | 4.51e-01 | 98.5% | 72.1% |
D2
medium
residues 16-67
D3
medium
residues 68-155
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF20155.5 best | TMP_3 | 54.2 | 2.30e-14 | 95.5% | 43.2% |
CATH (26)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1nvmA02 | 1.10.8.60 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.74 | 51.0 | 5.87e-01 | 87.5% | 98.4% |
| 1b25A02 | 1.10.569.10 | Mainly Alpha › Orthogonal Bundle › Aldehyde Ferredoxin Oxidoreductase Protein, subunit A; domain 2 › Aldehyde Ferredoxin Oxidoreductase Protein, subunit A, domain 2 | 0.66 | 55.0 | 4.46e-01 | 94.3% | 53.4% |
| 4jzaA03 | 1.20.120.1720 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.64 | 48.0 | 4.03e-01 | 80.7% | 90.2% |
| 5b2nA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.63 | 44.0 | 3.15e-01 | 72.7% | 35.0% |
| 4bemJ00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.62 | 51.0 | 4.06e-01 | 90.9% | 67.4% |
| 8h72B01 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.60 | 48.0 | 3.39e-01 | 89.8% | 80.7% |
| 6fhoA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.60 | 48.0 | 3.76e-01 | 89.8% | 83.7% |
| 3uorB02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.60 | 45.0 | 3.42e-01 | 79.5% | 73.8% |
| 2uxwA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.59 | 44.0 | 3.85e-01 | 78.4% | 83.8% |
| 1j8yF01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.58 | 40.0 | 4.08e-01 | 71.6% | 76.7% |
| 3lcnB00 | 1.10.340.40 | Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Nuclear abundant poly(A) RNA-bind protein 2, N-terminal domain | 0.58 | 41.0 | 4.01e-01 | 73.9% | 97.9% |
| 3c4aA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.57 | 45.0 | 3.50e-01 | 89.8% | 68.1% |
| 3fy6A01 | 3.30.2210.10 | Alpha Beta › 2-Layer Sandwich › Integron cassette protein fold › Integron cassette protein superfamily | 0.57 | 40.0 | 3.79e-01 | 73.9% | 78.5% |
| 1eu8A02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.55 | 42.0 | 3.23e-01 | 83.0% | 75.6% |
| 4ryaA02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.55 | 42.0 | 3.27e-01 | 83.0% | 74.9% |
| 2a0uB01 | 1.20.120.420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 | 0.55 | 39.0 | 3.23e-01 | 73.9% | 41.2% |
| 2uuiA00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.55 | 46.0 | 3.98e-01 | 100.0% | 85.8% |
| 1i6zA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.55 | 40.0 | 3.43e-01 | 76.1% | 80.7% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.54 | 39.0 | 3.78e-01 | 76.1% | 98.0% |
| 3d1uA03 | 1.20.1270.240 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.54 | 43.0 | 4.13e-01 | 87.5% | 82.2% |
| 1ydxA02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.54 | 30.0 | 3.00e-01 | 88.6% | 52.2% |
| 3zsuA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.53 | 36.0 | 3.31e-01 | 70.5% | 63.6% |
| 2yfaB01 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.51 | 36.0 | 3.31e-01 | 72.7% | 75.6% |
| 3vz3A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.51 | 42.0 | 2.98e-01 | 89.8% | 35.4% |
| 1zylA03 | 1.20.1270.170 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.50 | 40.0 | 3.88e-01 | 89.8% | 94.2% |
| 3rh9A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.50 | 40.0 | 2.85e-01 | 88.6% | 31.8% |
ECOD (22)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3963765 | 159.1.2.5 ↗ | alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related › TMP_3 | 0.92 | 82.0 | 6.16e-01 | 93.2% | 43.2% |
| 1719256 | 159.1.2.0 ↗ | alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related | 0.76 | 66.0 | 5.04e-01 | 94.3% | 50.5% |
| 4498700 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.67 | 49.0 | 4.70e-01 | 76.1% | 74.0% |
| 5012845 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.64 | 53.0 | 4.38e-01 | 88.6% | 83.1% |
| 3229734 | 5001.1.1.69 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srd | 0.61 | 43.0 | 2.93e-01 | 73.9% | 39.1% |
| 3933378 | 5001.1.1.60 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srx | 0.56 | 40.0 | 2.96e-01 | 75.0% | 48.0% |
| 4182480 | 2004.1.1.71 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › IPPT | 0.56 | 39.0 | 2.93e-01 | 73.9% | 98.3% |
| 3220230 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.56 | 49.0 | 3.35e-01 | 100.0% | 44.6% |
| 3391293 | 101.1.10.13 ↗ | alpha arrays › HTH › HTH › Cyclin-like › DUF3452 | 0.56 | 48.0 | 4.35e-01 | 96.6% | 98.3% |
| 4151484 | 5045.1.1.1 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A | 0.56 | 44.0 | 3.41e-01 | 86.4% | 83.0% |
| 3282612 | 5060.2.1.0 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain | 0.55 | 38.0 | 3.35e-01 | 71.6% | 64.6% |
| 4971986 | 3651.1.1.1 ↗ | alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › IF-2B | 0.54 | 37.0 | 3.53e-01 | 71.6% | 60.0% |
| 4454337 | 5068.1.1.1 ↗ | alpha bundles › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › Cytochrom_B_C | 0.54 | 42.0 | 3.61e-01 | 84.1% | 84.8% |
| 4951505 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.54 | 38.0 | 3.40e-01 | 73.9% | 70.4% |
| 2507447 | 611.4.1.2 ↗ | alpha bundles › N-cbl like › PG0775 C-terminal domain-like › PG0775 C-terminal domain-like › Acyl-CoA_dh_C | 0.53 | 42.0 | 3.83e-01 | 86.4% | 87.0% |
| 4979116 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.53 | 40.0 | 3.72e-01 | 81.8% | 93.9% |
| 3937860 | 633.6.1.6 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACAD9-ACADV_C | 0.52 | 43.0 | 3.55e-01 | 92.0% | 85.9% |
| 3970500 | 633.5.1.1 ↗ | alpha bundles › Bromodomain-like › LemA-like › LemA-like › LemA | 0.52 | 37.0 | 3.08e-01 | 75.0% | 56.2% |
| 3987419 | 140.1.1.7 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_2 | 0.51 | 41.0 | 3.80e-01 | 87.5% | 67.8% |
| 3744275 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.51 | 33.0 | 3.37e-01 | 88.6% | 68.2% |
| 3226437 | 633.6.1.6 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACAD9-ACADV_C | 0.50 | 38.0 | 3.18e-01 | 86.4% | 81.1% |
| 3959831 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.50 | 39.0 | 3.30e-01 | 84.1% | 64.0% |
D4
medium
residues 537-625
Domain cluster:
representative
CATH (74)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4he8D00 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.87 | 68.0 | 5.49e-01 | 95.5% | 45.6% |
| 8e9gK01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.87 | 73.0 | 7.29e-01 | 95.5% | 86.8% |
| 7zm7601 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.86 | 68.0 | 5.36e-01 | 95.5% | 43.7% |
| 7eu3E01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.86 | 75.0 | 7.66e-01 | 100.0% | 95.4% |
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.86 | 59.0 | 6.46e-01 | 70.8% | 89.2% |
| 6humG01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.85 | 69.0 | 5.59e-01 | 100.0% | 48.1% |
| 3rkoG00 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.84 | 73.0 | 7.00e-01 | 100.0% | 82.0% |
| 8e9gJ01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.84 | 66.0 | 5.31e-01 | 97.8% | 44.3% |
| 3rkoF01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.84 | 66.0 | 5.33e-01 | 96.6% | 46.3% |
| 4adzA00 | 1.20.58.1000 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer | 0.81 | 62.0 | 6.26e-01 | 80.9% | 100.0% |
| 4wpcA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.79 | 55.0 | 3.76e-01 | 70.8% | 49.5% |
| 6lumD01 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.78 | 66.0 | 5.79e-01 | 88.8% | 82.4% |
| 3a98A02 | 1.20.1270.350 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain | 0.78 | 51.0 | 5.16e-01 | 85.4% | 67.8% |
| 3m7gA02 | 1.10.8.1010 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.78 | 55.0 | 5.40e-01 | 74.2% | 68.4% |
| 3a8pA02 | 6.10.140.680 | Special › Helix non-globular › Helix Hairpins › | 0.77 | 61.0 | 5.52e-01 | 82.0% | 92.1% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.76 | 53.0 | 5.64e-01 | 71.9% | 83.3% |
| 7d3uC01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.76 | 65.0 | 6.12e-01 | 93.3% | 86.0% |
| 2xokP00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.76 | 52.0 | 5.61e-01 | 70.8% | 89.2% |
| 1zoyD00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.75 | 64.0 | 6.14e-01 | 92.1% | 80.4% |
| 2v5cA03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.75 | 64.0 | 5.55e-01 | 91.0% | 64.6% |
| 6xpdA01 | 1.20.1510.10 | Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain | 0.74 | 66.0 | 5.07e-01 | 100.0% | 43.6% |
| 1tqgA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.74 | 59.0 | 5.59e-01 | 94.4% | 71.4% |
| 2wdqD00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.74 | 64.0 | 6.10e-01 | 95.5% | 100.0% |
| 1e7pC00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.72 | 64.0 | 4.61e-01 | 98.9% | 83.1% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.72 | 64.0 | 5.61e-01 | 100.0% | 73.1% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.71 | 62.0 | 5.49e-01 | 96.6% | 70.8% |
| 1m6nA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.71 | 49.0 | 4.25e-01 | 70.8% | 48.9% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.71 | 51.0 | 4.71e-01 | 74.2% | 78.2% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.71 | 60.0 | 5.30e-01 | 94.4% | 64.7% |
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.70 | 51.0 | 3.61e-01 | 77.5% | 42.8% |
| 4bemJ00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.69 | 48.0 | 3.82e-01 | 71.9% | 35.9% |
| 1fs0G02 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.69 | 48.0 | 4.82e-01 | 71.9% | 83.1% |
| 2fji101 | 1.10.357.50 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.68 | 52.0 | 3.94e-01 | 80.9% | 70.8% |
| 1nlxA00 | 1.20.120.320 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Group V grass pollen allergen | 0.68 | 50.0 | 4.78e-01 | 89.9% | 66.3% |
| 4xpwA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.68 | 58.0 | 5.14e-01 | 94.4% | 67.2% |
| 1m56C02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.68 | 62.0 | 4.73e-01 | 98.9% | 53.6% |
| 8fbnB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.68 | 57.0 | 4.19e-01 | 89.9% | 43.7% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.68 | 60.0 | 5.54e-01 | 98.9% | 76.1% |
| 8a1gC01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.67 | 60.0 | 4.68e-01 | 95.5% | 86.7% |
| 7w9wA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.67 | 60.0 | 4.29e-01 | 100.0% | 40.5% |
| 1lm3B00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.66 | 55.0 | 5.25e-01 | 92.1% | 79.2% |
| 2l1lB00 | 1.20.1440.250 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.66 | 50.0 | 4.42e-01 | 93.3% | 55.9% |
| 6kobA01 | 1.20.210.10 | Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain | 0.66 | 56.0 | 3.40e-01 | 94.4% | 71.0% |
| 1wkbA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.65 | 44.0 | 4.05e-01 | 83.1% | 52.1% |
| 2b1eA02 | 1.20.1310.30 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › | 0.65 | 54.0 | 4.50e-01 | 89.9% | 76.2% |
| 2rd0B00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.65 | 45.0 | 3.87e-01 | 71.9% | 46.0% |
| 6gpxB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.64 | 57.0 | 4.08e-01 | 98.9% | 45.6% |
| 1dtoA01 | 1.10.287.30 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 | 0.64 | 58.0 | 5.52e-01 | 98.9% | 89.2% |
| 6xkyA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.64 | 56.0 | 4.29e-01 | 93.3% | 54.5% |
| 2genA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.64 | 45.0 | 3.54e-01 | 74.2% | 53.7% |
| 2etdA00 | 1.20.1440.20 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain | 0.63 | 53.0 | 4.56e-01 | 95.5% | 57.4% |
| 6srbA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.63 | 50.0 | 4.69e-01 | 84.3% | 83.5% |
| 6lumG01 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.63 | 53.0 | 4.92e-01 | 92.1% | 91.1% |
| 2gtsA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.63 | 45.0 | 4.75e-01 | 74.2% | 88.3% |
| 3ezuA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.63 | 57.0 | 4.35e-01 | 95.5% | 83.5% |
| 7wujE01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.62 | 53.0 | 3.85e-01 | 96.6% | 40.8% |
| 6nmnA02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.62 | 53.0 | 4.68e-01 | 94.4% | 71.1% |
| 5cy5B00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.61 | 52.0 | 4.45e-01 | 96.6% | 96.0% |
| 1orjD00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.61 | 50.0 | 4.47e-01 | 88.8% | 64.8% |
| 2o36A01 | 1.20.1050.40 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Endopeptidase. Chain P; domain 1 | 0.61 | 53.0 | 4.67e-01 | 94.4% | 89.8% |
| 1l8nA03 | 3.90.1330.10 | Alpha Beta › Alpha-Beta Complex › Alpha-d-glucuronidase, C-terminal Domain › Alpha-glucuronidase, C-terminal domain | 0.60 | 53.0 | 4.09e-01 | 100.0% | 85.4% |
| 2lqgA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.60 | 49.0 | 4.30e-01 | 92.1% | 69.6% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.59 | 50.0 | 4.19e-01 | 94.4% | 58.2% |
| 5kbwB00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.58 | 51.0 | 4.18e-01 | 100.0% | 77.2% |
| 3k66A01 | 1.20.120.770 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Amyloid precursor protein, E2 domain | 0.58 | 49.0 | 3.90e-01 | 100.0% | 80.4% |
| 2rbdA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.58 | 52.0 | 4.37e-01 | 100.0% | 94.7% |
| 2rkkA01 | 1.25.40.270 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 | 0.56 | 46.0 | 3.94e-01 | 100.0% | 53.2% |
| 2hz8A00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.56 | 46.0 | 4.36e-01 | 96.6% | 77.4% |
| 3t5vA00 | 1.25.40.990 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.56 | 49.0 | 3.36e-01 | 95.5% | 75.6% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 49.0 | 3.97e-01 | 100.0% | 76.9% |
| 3qc1A01 | 1.25.40.540 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TAP42-like family | 0.55 | 45.0 | 3.86e-01 | 92.1% | 55.6% |
| 4g12A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 46.0 | 3.93e-01 | 94.4% | 94.6% |
| 1hs7A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 47.0 | 4.64e-01 | 100.0% | 96.9% |
| 3vprA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 47.0 | 4.03e-01 | 100.0% | 98.6% |
ECOD (77)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5018859 | 3579.1.1.1 ↗ | extended segments › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › Oxidored_q3 | 0.87 | 71.0 | 5.65e-01 | 100.0% | 46.7% |
| 4379577 | 3843.1.1.1 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 | 0.86 | 77.0 | 7.12e-01 | 100.0% | 77.3% |
| 4049949 | 3843.1.1.6 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › MrpF_PhaF | 0.86 | 75.0 | 7.52e-01 | 100.0% | 92.2% |
| 4498502 | 3843.1.1.6 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › MrpF_PhaF | 0.86 | 75.0 | 7.33e-01 | 100.0% | 87.4% |
| 4683274 | 3843.1.1.6 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › MrpF_PhaF | 0.86 | 72.0 | 7.59e-01 | 97.8% | 100.0% |
| 5025118 | 3843.1.1.1 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 | 0.85 | 77.0 | 7.40e-01 | 98.9% | 86.0% |
| 4201688 | 3843.1.1.1 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 | 0.85 | 74.0 | 7.29e-01 | 100.0% | 87.4% |
| 3971927 | 3843.1.1.0 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K | 0.85 | 72.0 | 7.45e-01 | 95.5% | 95.2% |
| 4245573 | 3843.1.1.1 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 | 0.85 | 73.0 | 6.93e-01 | 100.0% | 78.8% |
| 4272210 | 3579.1.1.1 ↗ | extended segments › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › Oxidored_q3 | 0.85 | 68.0 | 5.25e-01 | 96.6% | 41.7% |
| 3958163 | 3843.1.1.0 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K | 0.84 | 72.0 | 6.94e-01 | 100.0% | 81.8% |
| 5001524 | 3843.1.1.1 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 | 0.84 | 76.0 | 7.42e-01 | 100.0% | 90.5% |
| 4449483 | 3843.1.1.1 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 | 0.84 | 74.0 | 6.97e-01 | 100.0% | 80.0% |
| 4490049 | 3843.1.1.6 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › MrpF_PhaF | 0.84 | 74.0 | 7.42e-01 | 100.0% | 93.3% |
| 2578415 | 3579.1.1.1 ↗ | extended segments › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › Oxidored_q3 | 0.84 | 68.0 | 5.43e-01 | 100.0% | 45.3% |
| 5047618 | 3843.1.1.1 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 | 0.84 | 73.0 | 6.92e-01 | 100.0% | 80.0% |
| 4499656 | 3843.1.1.4 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › PhaG_MnhG_YufB | 0.83 | 77.0 | 6.52e-01 | 100.0% | 65.0% |
| 5006027 | 3843.1.1.1 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 | 0.83 | 69.0 | 6.77e-01 | 96.6% | 83.2% |
| 4947364 | 3843.1.1.0 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K | 0.83 | 72.0 | 7.09e-01 | 96.6% | 87.4% |
| 4928814 | 3843.1.1.1 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 | 0.82 | 69.0 | 6.56e-01 | 100.0% | 76.9% |
| 5009337 | 3579.1.1.1 ↗ | extended segments › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › Oxidored_q3 | 0.82 | 68.0 | 5.54e-01 | 100.0% | 49.4% |
| 4040950 | 3843.1.1.4 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › PhaG_MnhG_YufB | 0.81 | 75.0 | 6.88e-01 | 100.0% | 79.6% |
| 4932209 | 3843.1.1.6 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › MrpF_PhaF | 0.81 | 68.0 | 7.12e-01 | 97.8% | 100.0% |
| 4964136 | 3843.1.1.6 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › MrpF_PhaF | 0.81 | 68.0 | 7.01e-01 | 98.9% | 95.3% |
| 5014425 | 3843.1.1.1 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 | 0.81 | 72.0 | 6.50e-01 | 96.6% | 84.9% |
| 4945431 | 3843.1.1.0 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K | 0.80 | 71.0 | 6.80e-01 | 100.0% | 85.0% |
| 4944098 | 3843.1.1.0 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K | 0.80 | 70.0 | 6.76e-01 | 100.0% | 85.0% |
| 4931253 | 3843.1.1.1 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 | 0.80 | 72.0 | 6.61e-01 | 98.9% | 87.8% |
| 5021415 | 3579.1.1.33 ↗ | extended segments › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › PsiE | 0.78 | 66.0 | 5.85e-01 | 92.1% | 68.8% |
| 3770066 | 3291.1.1.169 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › KIF21A_4th | 0.77 | 51.0 | 3.93e-01 | 71.9% | 31.3% |
| 3481099 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.77 | 56.0 | 3.94e-01 | 75.3% | 27.7% |
| 4941521 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.77 | 67.0 | 6.57e-01 | 93.3% | 93.7% |
| 3603155 | 3843.1.1.1 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 | 0.77 | 69.0 | 6.17e-01 | 100.0% | 83.2% |
| 3923570 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.77 | 65.0 | 4.28e-01 | 87.6% | 31.8% |
| 4550967 | 3843.1.1.29 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › DUF2105 | 0.76 | 62.0 | 6.22e-01 | 95.5% | 84.4% |
| 3253260 | 5069.1.3.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › CybS | 0.76 | 68.0 | 6.33e-01 | 97.8% | 85.3% |
| 3955107 | 106.1.1.11 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › RsbRD_N | 0.76 | 64.0 | 5.29e-01 | 91.0% | 84.5% |
| 4987192 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.75 | 64.0 | 5.66e-01 | 89.9% | 71.0% |
| 4954727 | 3843.1.1.1 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 | 0.75 | 63.0 | 6.09e-01 | 100.0% | 83.0% |
| 3837728 | 3843.1.1.0 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K | 0.74 | 66.0 | 5.63e-01 | 95.5% | 78.5% |
| 3913300 | 3755.3.1.303 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A_4th | 0.73 | 51.0 | 4.23e-01 | 71.9% | 42.7% |
| 4020563 | 601.16.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › GIT1_C | 0.72 | 67.0 | 5.83e-01 | 100.0% | 68.5% |
| 3242453 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.69 | 60.0 | 4.56e-01 | 96.6% | 42.8% |
| 4025636 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.69 | 48.0 | 3.98e-01 | 71.9% | 44.9% |
| 4952624 | 3843.1.1.29 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › DUF2105 | 0.69 | 58.0 | 5.96e-01 | 98.9% | 94.1% |
| 5080053 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.69 | 60.0 | 5.22e-01 | 95.5% | 65.9% |
| 5045256 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.69 | 59.0 | 5.74e-01 | 88.8% | 89.5% |
| 3472795 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.69 | 49.0 | 4.32e-01 | 74.2% | 51.5% |
| 4981575 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.69 | 59.0 | 5.21e-01 | 96.6% | 65.9% |
| 3512620 | 3755.4.1.1 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PI3K_P85_iSH2 | 0.69 | 48.0 | 3.91e-01 | 71.9% | 41.2% |
| 4941675 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.68 | 47.0 | 2.92e-01 | 70.8% | 15.1% |
| 4973614 | 5069.1.3.26 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DUF1622 | 0.68 | 59.0 | 5.56e-01 | 98.9% | 90.0% |
| 4998325 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.67 | 60.0 | 5.42e-01 | 98.9% | 80.0% |
| 4957771 | 5069.1.3.137 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DUF7521 | 0.67 | 59.0 | 5.88e-01 | 94.4% | 97.8% |
| 4999868 | 604.1.1.264 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Oxidored_q2 | 0.66 | 59.0 | 5.89e-01 | 100.0% | 97.8% |
| 4017049 | 109.62.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › AFF4 C-terminal homology domain › AFF4 C-terminal homology domain | 0.66 | 59.0 | 4.14e-01 | 98.9% | 33.3% |
| 3971935 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.66 | 57.0 | 5.29e-01 | 94.4% | 83.6% |
| 5032752 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.66 | 55.0 | 5.67e-01 | 94.4% | 100.0% |
| 3488158 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.65 | 50.0 | 4.43e-01 | 79.8% | 65.6% |
| 3589446 | 2004.1.1.301 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_27 | 0.65 | 48.0 | 3.03e-01 | 77.5% | 48.0% |
| 3669330 | 604.1.1.148 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › TBCC_N | 0.65 | 60.0 | 6.15e-01 | 97.8% | 100.0% |
| 4803706 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.65 | 56.0 | 4.45e-01 | 91.0% | 86.8% |
| 4609203 | 5069.1.3.10 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › ATP-synt_I | 0.65 | 54.0 | 5.06e-01 | 95.5% | 80.9% |
| 4982132 | 5069.1.3.135 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DUF5985 | 0.65 | 55.0 | 5.50e-01 | 98.9% | 91.5% |
| 3940752 | 5001.1.1.60 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srx | 0.65 | 55.0 | 3.87e-01 | 95.5% | 40.7% |
| 3939260 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.65 | 57.0 | 5.53e-01 | 96.6% | 93.0% |
| 4999123 | 604.12.1.135 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Oxidored_q2 | 0.62 | 56.0 | 5.32e-01 | 100.0% | 87.6% |
| 3507250 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.62 | 57.0 | 5.36e-01 | 98.9% | 91.4% |
| 2642640 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.62 | 56.0 | 4.60e-01 | 96.6% | 65.1% |
| 3706543 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 53.0 | 3.29e-01 | 100.0% | 21.1% |
| 3507828 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.59 | 48.0 | 3.31e-01 | 87.6% | 71.7% |
| 3368923 | 7064.1.1.1 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 | 0.59 | 53.0 | 4.27e-01 | 100.0% | 99.4% |
| 3562849 | 148.1.3.254 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › KIF21A_4th | 0.59 | 52.0 | 3.88e-01 | 98.9% | 73.5% |
| 4030348 | 2498.1.1.6 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 | 0.54 | 46.0 | 2.83e-01 | 97.8% | 13.9% |
| 3739906 | 109.4.1.1396 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › IBN_N, TPR_IPO5 | 0.53 | 46.0 | 2.83e-01 | 95.5% | 15.4% |
| 1144728 | 604.12.1.2 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 | 0.53 | 46.0 | 4.56e-01 | 98.9% | 92.6% |
| 3705018 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 46.0 | 3.31e-01 | 96.6% | 52.9% |
D5
medium
residues 626-734
Domain cluster:
representative
CATH (45)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5cy5B00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.82 | 45.0 | 3.96e-01 | 71.6% | 39.6% |
| 3rkoG00 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.80 | 59.0 | 6.21e-01 | 87.2% | 84.0% |
| 7eu3E01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.78 | 59.0 | 6.52e-01 | 87.2% | 98.9% |
| 8e9gK01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.78 | 56.0 | 6.07e-01 | 86.2% | 89.0% |
| 3a8pA02 | 6.10.140.680 | Special › Helix non-globular › Helix Hairpins › | 0.75 | 52.0 | 5.20e-01 | 71.6% | 90.4% |
| 2chnB03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.74 | 54.0 | 4.54e-01 | 78.9% | 46.1% |
| 2v0xA01 | 1.10.287.3160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.71 | 58.0 | 4.97e-01 | 86.2% | 83.3% |
| 1r0dA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.70 | 57.0 | 4.75e-01 | 89.0% | 49.7% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.69 | 55.0 | 5.20e-01 | 85.3% | 72.3% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.69 | 49.0 | 4.40e-01 | 78.0% | 53.0% |
| 1zoyD00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.69 | 53.0 | 5.48e-01 | 82.6% | 86.3% |
| 6lumD01 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.66 | 49.0 | 4.70e-01 | 78.0% | 84.8% |
| 6k6iA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.66 | 52.0 | 4.22e-01 | 90.8% | 43.4% |
| 3ajmB02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.64 | 50.0 | 4.70e-01 | 88.1% | 68.4% |
| 3ezuA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.64 | 44.0 | 3.72e-01 | 71.6% | 72.0% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.64 | 46.0 | 4.62e-01 | 82.6% | 72.6% |
| 1lm3B00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.63 | 46.0 | 4.72e-01 | 80.7% | 80.2% |
| 7zm7601 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.62 | 56.0 | 4.74e-01 | 94.5% | 100.0% |
| 2fji101 | 1.10.357.50 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.62 | 45.0 | 3.61e-01 | 74.3% | 67.9% |
| 2l7nA00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.62 | 51.0 | 4.48e-01 | 89.9% | 58.3% |
| 4he8D00 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.62 | 56.0 | 4.86e-01 | 97.2% | 100.0% |
| 8befJ01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.61 | 55.0 | 4.68e-01 | 95.4% | 100.0% |
| 2etdA00 | 1.20.1440.20 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain | 0.61 | 47.0 | 4.31e-01 | 89.0% | 62.4% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.61 | 46.0 | 4.50e-01 | 88.1% | 72.7% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.60 | 48.0 | 3.66e-01 | 88.1% | 80.7% |
| 5lnkJ01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.60 | 54.0 | 4.58e-01 | 95.4% | 100.0% |
| 6xxvC00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.60 | 43.0 | 4.34e-01 | 74.3% | 79.3% |
| 2vzbB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.60 | 51.0 | 4.40e-01 | 91.7% | 91.0% |
| 1dd5A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.60 | 47.0 | 4.78e-01 | 84.4% | 97.2% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.60 | 40.0 | 4.63e-01 | 82.6% | 100.0% |
| 6humG01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.59 | 53.0 | 4.67e-01 | 98.2% | 98.8% |
| 3rkoF01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.59 | 54.0 | 4.69e-01 | 98.2% | 100.0% |
| 4huqS00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.57 | 42.0 | 3.70e-01 | 80.7% | 51.2% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.56 | 45.0 | 4.81e-01 | 87.2% | 97.8% |
| 2yjkC00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.56 | 46.0 | 4.10e-01 | 89.9% | 89.8% |
| 2hkuB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 44.0 | 3.71e-01 | 87.2% | 74.6% |
| 4akgA02 | 1.20.140.100 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain | 0.54 | 47.0 | 4.12e-01 | 96.3% | 95.8% |
| 3rm5B02 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.53 | 41.0 | 3.35e-01 | 86.2% | 69.2% |
| 2b1eA02 | 1.20.1310.30 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › | 0.52 | 40.0 | 3.60e-01 | 81.7% | 61.6% |
| 4g12A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 40.0 | 3.64e-01 | 82.6% | 66.4% |
| 1f2eA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 35.0 | 3.64e-01 | 71.6% | 81.1% |
| 4wr4A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 36.0 | 3.66e-01 | 71.6% | 86.7% |
| 2iu5B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 38.0 | 3.29e-01 | 79.8% | 49.7% |
| 3dcfA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.50 | 43.0 | 3.99e-01 | 94.5% | 97.9% |
| 3himA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.50 | 41.0 | 3.47e-01 | 89.9% | 96.3% |
ECOD (57)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3963743 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.81 | 66.0 | 6.76e-01 | 86.2% | 96.2% |
| 5034580 | 3843.1.1.4 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › PhaG_MnhG_YufB | 0.80 | 62.0 | 6.51e-01 | 88.1% | 89.0% |
| 4379577 | 3843.1.1.1 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 | 0.80 | 61.0 | 6.09e-01 | 87.2% | 78.2% |
| 4964135 | 3843.1.1.4 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › PhaG_MnhG_YufB | 0.80 | 62.0 | 6.47e-01 | 88.1% | 89.0% |
| 5025118 | 3843.1.1.1 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 | 0.79 | 62.0 | 6.44e-01 | 88.1% | 89.0% |
| 5047618 | 3843.1.1.1 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 | 0.78 | 59.0 | 6.00e-01 | 87.2% | 81.9% |
| 4129121 | 3843.1.1.4 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › PhaG_MnhG_YufB | 0.77 | 59.0 | 6.16e-01 | 86.2% | 87.0% |
| 5001524 | 3843.1.1.1 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 | 0.77 | 60.0 | 6.35e-01 | 87.2% | 92.6% |
| 5013803 | 3843.1.1.4 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › PhaG_MnhG_YufB | 0.77 | 61.0 | 5.86e-01 | 87.2% | 73.6% |
| 4201688 | 3843.1.1.1 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 | 0.77 | 58.0 | 6.17e-01 | 87.2% | 90.5% |
| 3285485 | 191.1.1.64 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › DUF4254 | 0.75 | 50.0 | 4.37e-01 | 75.2% | 47.1% |
| 4944098 | 3843.1.1.0 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K | 0.75 | 56.0 | 5.84e-01 | 86.2% | 85.0% |
| 3290011 | 3843.1.1.4 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › PhaG_MnhG_YufB | 0.74 | 57.0 | 6.04e-01 | 86.2% | 92.6% |
| 4246492 | 3843.1.1.4 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › PhaG_MnhG_YufB | 0.74 | 57.0 | 6.09e-01 | 88.1% | 93.7% |
| 4031043 | 3939.1.1.0 ↗ | alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain | 0.72 | 58.0 | 5.68e-01 | 86.2% | 93.3% |
| 3653618 | 5069.1.3.69 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › ETR1_N | 0.72 | 52.0 | 5.59e-01 | 76.1% | 87.4% |
| 3225544 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.71 | 51.0 | 5.29e-01 | 73.4% | 85.0% |
| 4954727 | 3843.1.1.1 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 | 0.70 | 53.0 | 5.48e-01 | 87.2% | 86.0% |
| 3684830 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.70 | 48.0 | 5.04e-01 | 70.6% | 88.0% |
| 5037104 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.69 | 55.0 | 5.21e-01 | 82.6% | 76.8% |
| 5057848 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.69 | 57.0 | 5.76e-01 | 89.9% | 89.1% |
| 3572303 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.68 | 53.0 | 5.01e-01 | 86.2% | 69.2% |
| 3732719 | 601.1.1.25 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › GIT1_C | 0.68 | 56.0 | 5.22e-01 | 87.2% | 71.9% |
| 4129436 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.68 | 48.0 | 4.88e-01 | 71.6% | 90.5% |
| 3849157 | 192.29.1.11 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › FerA | 0.68 | 52.0 | 5.03e-01 | 81.7% | 76.0% |
| 3467780 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.68 | 51.0 | 4.62e-01 | 79.8% | 58.0% |
| 3482066 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.67 | 52.0 | 3.77e-01 | 80.7% | 69.8% |
| 3733697 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.67 | 55.0 | 3.63e-01 | 88.1% | 64.7% |
| 3932773 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.67 | 58.0 | 4.64e-01 | 92.7% | 62.9% |
| 3509997 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.67 | 49.0 | 4.00e-01 | 77.1% | 73.2% |
| 3922171 | 5057.1.1.1 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb | 0.66 | 48.0 | 4.25e-01 | 75.2% | 62.0% |
| 3946106 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.66 | 59.0 | 3.89e-01 | 97.2% | 40.7% |
| 4980095 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.66 | 49.0 | 5.05e-01 | 78.0% | 90.5% |
| 4682501 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.65 | 45.0 | 4.75e-01 | 70.6% | 92.0% |
| 3710148 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.65 | 51.0 | 4.05e-01 | 83.5% | 43.6% |
| 4525096 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.65 | 51.0 | 4.45e-01 | 83.5% | 88.5% |
| 4005538 | 5058.1.1.14 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MscS_TM | 0.65 | 59.0 | 4.25e-01 | 97.2% | 60.7% |
| 3579297 | 603.3.1.1 ↗ | alpha bundles › STAT-like › CAPPD, an extracellular domain of amyloid beta A4 protein › CAPPD, an extracellular domain of amyloid beta A4 protein › APP_E2 | 0.65 | 53.0 | 4.65e-01 | 89.0% | 63.6% |
| 3516673 | 601.33.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › PPP1R21_helical | 0.65 | 52.0 | 4.52e-01 | 86.2% | 67.9% |
| 5074225 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.64 | 50.0 | 5.38e-01 | 82.6% | 98.9% |
| 4025746 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.63 | 47.0 | 4.11e-01 | 78.9% | 71.8% |
| 4936976 | 633.10.1.2 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › Bbp7-like | 0.63 | 48.0 | 4.91e-01 | 82.6% | 82.9% |
| 3990526 | 4177.1.1.4 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › IMD | 0.62 | 50.0 | 3.95e-01 | 86.2% | 72.2% |
| 3962012 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.60 | 48.0 | 5.17e-01 | 87.2% | 98.9% |
| 4030302 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.60 | 48.0 | 4.48e-01 | 86.2% | 72.6% |
| 4613593 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.59 | 47.0 | 4.15e-01 | 88.1% | 57.5% |
| 3592993 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.59 | 48.0 | 4.53e-01 | 89.0% | 97.0% |
| 3939680 | 4177.1.1.3 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Arfaptin | 0.59 | 46.0 | 3.62e-01 | 84.4% | 80.0% |
| 3303315 | 603.1.1.3 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE | 0.58 | 49.0 | 4.47e-01 | 94.5% | 69.3% |
| 3237954 | 603.1.1.139 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE_C, PF27021 | 0.57 | 50.0 | 4.49e-01 | 97.2% | 91.6% |
| 3276921 | 603.1.1.3 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE | 0.56 | 50.0 | 4.54e-01 | 96.3% | 73.8% |
| 3610860 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.56 | 46.0 | 4.22e-01 | 87.2% | 67.9% |
| 3927597 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.55 | 45.0 | 4.43e-01 | 89.0% | 95.0% |
| 3212811 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.55 | 47.0 | 4.49e-01 | 93.6% | 85.4% |
| 3704699 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.55 | 44.0 | 4.64e-01 | 86.2% | 97.9% |
| 3497934 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.55 | 47.0 | 3.63e-01 | 94.5% | 72.8% |
| 3960407 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.54 | 40.0 | 3.73e-01 | 78.0% | 100.0% |
D6
medium
residues 735-785
Domain cluster:
representative
CATH (25)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3dd9D02 | 6.10.140.2060 | Special › Helix non-globular › Helix Hairpins › | 0.87 | 65.0 | 7.08e-01 | 84.3% | 100.0% |
| 4ex8A00 | 3.40.1790.10 | Alpha Beta › 3-Layer(aba) Sandwich › Indigoidine synthase fold › Indigoidine synthase domain | 0.81 | 62.0 | 3.80e-01 | 88.2% | 14.3% |
| 3vm9A02 | 6.10.140.2110 | Special › Helix non-globular › Helix Hairpins › | 0.73 | 62.0 | 6.09e-01 | 100.0% | 89.5% |
| 1j78A05 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.72 | 56.0 | 5.34e-01 | 86.3% | 73.3% |
| 1e94A00 | 3.60.20.10 | Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain | 0.71 | 55.0 | 3.85e-01 | 88.2% | 25.9% |
| 6mh4A03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.70 | 52.0 | 4.56e-01 | 96.1% | 53.2% |
| 3e3vA03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.69 | 50.0 | 4.94e-01 | 82.4% | 75.0% |
| 3uw3A02 | 3.30.360.10 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 | 0.68 | 57.0 | 3.74e-01 | 98.0% | 21.7% |
| 6humG01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.67 | 59.0 | 4.12e-01 | 100.0% | 31.9% |
| 1hlvA02 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.65 | 48.0 | 4.66e-01 | 96.1% | 71.7% |
| 1b3qA01 | 1.10.287.560 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain | 0.65 | 44.0 | 4.22e-01 | 76.5% | 59.7% |
| 3tixB03 | 3.40.50.11490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.65 | 50.0 | 3.57e-01 | 98.0% | 28.9% |
| 4e2aA00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.64 | 50.0 | 3.62e-01 | 100.0% | 27.6% |
| 1fioA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 53.0 | 3.68e-01 | 100.0% | 38.4% |
| 4ixjA01 | 3.30.1300.80 | Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › | 0.63 | 52.0 | 4.64e-01 | 96.1% | 63.6% |
| 2oq1A02 | 1.10.930.10 | Mainly Alpha › Orthogonal Bundle › Syk Kinase; Chain A, domain 2 › Syk Kinase; Chain A, domain 2 | 0.63 | 47.0 | 4.95e-01 | 94.1% | 93.3% |
| 3w42A00 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.63 | 45.0 | 3.12e-01 | 80.4% | 20.6% |
| 3k6hA01 | 3.40.109.10 | Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase | 0.62 | 54.0 | 3.77e-01 | 98.0% | 68.9% |
| 3d5lA03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.62 | 45.0 | 4.52e-01 | 82.4% | 80.8% |
| 5c9gA02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.61 | 45.0 | 4.38e-01 | 82.4% | 80.7% |
| 1zmbA02 | 6.10.170.10 | Special › Helix non-globular › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › | 0.60 | 40.0 | 4.51e-01 | 96.1% | 100.0% |
| 6ofuA00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.57 | 42.0 | 2.93e-01 | 98.0% | 90.7% |
| 3eo8A00 | 3.40.109.10 | Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase | 0.57 | 46.0 | 3.15e-01 | 100.0% | 65.3% |
| 4q5rA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.55 | 47.0 | 3.71e-01 | 100.0% | 45.5% |
| 3o2iA00 | 3.30.70.2710 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.55 | 39.0 | 3.34e-01 | 82.4% | 44.1% |
ECOD (21)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3408346 | 633.24.1.2 ↗ | alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain › DUF5601 | 0.85 | 74.0 | 6.48e-01 | 98.0% | 65.3% |
| 4319975 | 547.1.1.1 ↗ | alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer | 0.83 | 73.0 | 6.02e-01 | 100.0% | 55.6% |
| 3414564 | 2008.1.1.29 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Dna2 | 0.81 | 68.0 | 4.25e-01 | 96.1% | 17.5% |
| 3278450 | 547.1.1.1 ↗ | alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer | 0.78 | 67.0 | 5.80e-01 | 100.0% | 62.5% |
| 3588971 | 6026.1.1.0 ↗ | alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain | 0.77 | 68.0 | 5.97e-01 | 100.0% | 77.3% |
| 5024091 | 102.1.1.0 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like | 0.76 | 57.0 | 5.19e-01 | 84.3% | 60.0% |
| None | — | 0.75 | 66.0 | 4.15e-01 | 100.0% | 18.9% | |
| 4883357 | 171.1.1.4 ↗ | alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonucleas_3_3 | 0.74 | 62.0 | 5.03e-01 | 96.1% | 75.8% |
| 3823868 | 171.1.1.4 ↗ | alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonucleas_3_3 | 0.73 | 61.0 | 4.33e-01 | 96.1% | 46.9% |
| 3624309 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.73 | 62.0 | 4.66e-01 | 100.0% | 38.5% |
| 3637620 | 4336.2.1.0 ↗ | alpha duplicates or obligate multimers › YheA/YmcA-like › Protein SUS1 › Protein SUS1 | 0.73 | 62.0 | 5.14e-01 | 98.0% | 54.4% |
| 3441581 | 103.4.1.5 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › KIX_2 | 0.72 | 62.0 | 5.60e-01 | 100.0% | 71.4% |
| 4652188 | 171.1.1.1 ↗ | alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 | 0.70 | 57.0 | 4.21e-01 | 96.1% | 60.0% |
| 4304782 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.68 | 54.0 | 4.67e-01 | 100.0% | 55.3% |
| 4371007 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.68 | 58.0 | 4.96e-01 | 100.0% | 63.5% |
| 3244904 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.66 | 49.0 | 3.36e-01 | 86.3% | 20.5% |
| 1566530 | 198.1.1.2 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2,SapB_1 | 0.66 | 51.0 | 4.50e-01 | 90.2% | 55.6% |
| 3252439 | 198.1.1.10 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2, SapB_1, Saposin | 0.65 | 47.0 | 4.18e-01 | 84.3% | 51.2% |
| 4646540 | 223.2.1.18 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like › Longin_2 | 0.64 | 52.0 | 3.72e-01 | 100.0% | 29.4% |
| 3680918 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.63 | 53.0 | 5.00e-01 | 100.0% | 76.9% |
| 3830162 | 109.4.1.83 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Suf | 0.50 | 42.0 | 2.88e-01 | 96.1% | 50.5% |