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ON453900.1WAK79507.1X__00083

Bact-Vir

ON453900.1__WAK79507.1__X__00083

Identity

Accession:: ON453900 ↗
Kingdom:: phage

Quality

47.4 mean pLDDT

Taxonomy

Clostridium_phage_Maintenon

TaxID: 2951972

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1290-1360

PDB

Domain cluster: representative

CATH (31)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3d36B02	1.10.287.130	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain	0.82	37.0	4.02e-01	95.8%	52.5%
1c17M00	1.20.120.220	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ATP synthase, F0 complex, subunit A	0.76	55.0	4.32e-01	77.5%	38.0%
2p5tA00	1.10.8.130	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 ›	0.75	67.0	6.14e-01	100.0%	96.7%
4i0xG00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.73	52.0	5.38e-01	80.3%	77.9%
2oexA01	1.20.120.560	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain	0.72	64.0	5.10e-01	100.0%	89.5%
2db7A01	6.10.250.980	Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces ›	0.69	49.0	5.36e-01	77.5%	100.0%
3favD00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.69	51.0	5.01e-01	80.3%	74.4%
3djbA01	1.10.472.50	Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › HD-domain/PDEase-like	0.68	50.0	4.61e-01	80.3%	63.5%
3pe0A02	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.68	64.0	5.47e-01	100.0%	97.2%
1skvA00	1.10.287.660	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.66	45.0	4.69e-01	71.8%	78.1%
2vixA03	1.20.1280.240	Mainly Alpha › Up-down Bundle › Monooxygenase ›	0.65	51.0	4.38e-01	84.5%	91.2%
6p73A02	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.65	57.0	4.55e-01	98.6%	66.4%
3icxA01	1.10.287.660	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.65	50.0	4.95e-01	81.7%	77.3%
1ydxA02	1.10.287.1120	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein	0.64	50.0	4.57e-01	81.7%	67.8%
3hr0B01	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.64	50.0	4.80e-01	81.7%	73.4%
1f45B00	1.20.1250.10	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; ›	0.64	48.0	3.90e-01	80.3%	58.6%
1gaxA05	1.10.287.380	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain	0.62	46.0	4.58e-01	77.5%	76.7%
4e6nA02	6.10.140.1010	Special › Helix non-globular › Helix Hairpins ›	0.62	45.0	4.68e-01	81.7%	83.3%
3safA02	1.10.150.80	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › HRDC domain	0.62	47.0	4.24e-01	83.1%	65.0%
3cymA03	1.10.150.80	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › HRDC domain	0.61	47.0	4.41e-01	83.1%	78.4%
2a3qA00	1.10.287.1080	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like	0.61	42.0	3.64e-01	71.8%	46.0%
1rp3A01	1.10.1740.10	Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif	0.61	52.0	4.97e-01	97.2%	95.3%
1s35A02	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.60	46.0	3.96e-01	81.7%	54.5%
1cnt200	1.20.1250.10	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; ›	0.60	53.0	4.25e-01	94.4%	73.1%
1xfiA02	1.20.1700.10	Mainly Alpha › Up-down Bundle › AF1104-like › AF1104-like	0.60	50.0	4.71e-01	94.4%	97.8%
2zxqA06	1.20.1270.70	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle	0.58	44.0	4.59e-01	84.5%	98.5%
2lw1A00	1.10.287.380	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain	0.57	41.0	3.86e-01	74.6%	65.9%
4ceiA03	6.10.250.2380	Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces ›	0.57	50.0	4.32e-01	100.0%	69.6%
1ybzA00	1.20.59.10	Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase	0.55	52.0	5.12e-01	100.0%	100.0%
2g47A04	3.30.830.10	Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like	0.53	41.0	2.92e-01	87.3%	72.9%
1xo0A01	1.10.150.130	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain	0.52	40.0	3.43e-01	81.7%	77.5%

ECOD (30)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3272278	3722.1.1.0 ↗	alpha bundles › Protein regulator of cytokinesis 1 (PRC1) rod domain › Protein regulator of cytokinesis 1 (PRC1) rod domain › Protein regulator of cytokinesis 1 (PRC1) rod domain	0.78	71.0	4.67e-01	100.0%	27.5%
3953372	150.5.1.1 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100	0.76	58.0	5.14e-01	80.3%	58.2%
5059279	632.11.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like	0.75	67.0	6.43e-01	97.2%	93.8%
4059363	142.3.1.1 ↗	alpha complex topology › Sigma2 domain-like › Mitochondrial morphogenesis protein Sld7 C-terminal domain › Mitochondrial morphogenesis protein Sld7 C-terminal domain › Sld7_C	0.75	66.0	6.12e-01	98.6%	96.7%
4956012	632.11.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like	0.74	69.0	5.96e-01	100.0%	84.8%
3383371	3722.1.1.1 ↗	alpha bundles › Protein regulator of cytokinesis 1 (PRC1) rod domain › Protein regulator of cytokinesis 1 (PRC1) rod domain › Protein regulator of cytokinesis 1 (PRC1) rod domain › MAP65_ASE1	0.74	67.0	4.27e-01	100.0%	25.6%
3962961	150.5.1.53 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PPE	0.73	52.0	5.00e-01	74.6%	71.2%
3308724	3721.1.1.2 ↗	alpha bundles › Protein regulator of cytokinesis 1 (PRC1) dimerization domain › Protein regulator of cytokinesis 1 (PRC1) dimerization domain › Protein regulator of cytokinesis 1 (PRC1) dimerization domain › MAP65_ASE1	0.73	65.0	6.00e-01	100.0%	83.3%
3989535	632.6.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit	0.73	64.0	5.85e-01	100.0%	95.8%
5060802	632.11.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like	0.72	65.0	6.13e-01	100.0%	88.2%
3598426	3615.1.1.0 ↗	alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain	0.71	63.0	5.33e-01	100.0%	68.9%
3287601	150.5.1.1 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100	0.71	51.0	4.65e-01	76.1%	64.9%
5012657	632.11.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like	0.69	59.0	5.45e-01	98.6%	86.3%
4964238	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.68	50.0	5.00e-01	81.7%	76.0%
3413774	632.15.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN)	0.67	55.0	4.67e-01	88.7%	61.7%
3736652	192.29.1.102 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Fung_rhodopsin	0.67	48.0	4.60e-01	78.9%	66.3%
3892225	6157.1.1.1 ↗	alpha bundles › GKAP homology domain 1 › GKAP homology domain 1 › GKAP homology domain 1 › GKAP	0.66	59.0	5.03e-01	100.0%	93.9%
3925160	9.26.1.0 ↗	beta barrels › Lipocalins/Streptavidin	0.64	49.0	3.58e-01	81.7%	31.6%
3591437	601.29.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › TM1646-like › TM1646-like	0.64	47.0	4.20e-01	77.5%	59.0%
5052428	605.6.1.0 ↗	alpha duplicates or obligate multimers › ROP-like › HP1531-like › HP1531-like	0.64	46.0	4.43e-01	77.5%	76.2%
1874545	139.4.1.0 ↗	few secondary structure elements › Multiheme cytochromes › Outer membrane cytochrome MtrF › Outer membrane cytochrome MtrF	0.64	56.0	3.24e-01	98.6%	13.8%
4304389	5086.1.1.119 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › RRG1_C	0.63	55.0	3.84e-01	95.8%	31.4%
3932694	604.5.1.0 ↗	alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895)	0.61	44.0	4.00e-01	78.9%	57.0%
4010395	622.4.1.26 ↗	alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › HisKA	0.59	47.0	4.77e-01	84.5%	88.6%
3583440	604.1.1.1 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin	0.59	52.0	4.42e-01	100.0%	86.7%
3280119	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.59	50.0	3.83e-01	98.6%	95.6%
3982421	605.1.1.1 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA	0.59	46.0	4.60e-01	84.5%	82.7%
5014266	632.11.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like	0.58	46.0	4.58e-01	88.7%	85.3%
2067201	5086.1.1.84 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND	0.57	43.0	4.21e-01	81.7%	75.3%
4944926	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.53	46.0	3.35e-01	98.6%	68.3%

D2 medium residues 351-486

PDB

Domain cluster: rep: HQ332138.1__AGN33733.1__PANG_00012__00012__D45-207

CATH (19)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2o7gA00	1.10.1740.10	Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif	0.67	36.0	4.33e-01	82.4%	79.5%
1u84A00	1.10.340.20	Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Apc36109-like domain	0.62	30.0	3.87e-01	77.9%	77.8%
1f81A00	1.20.1020.10	Mainly Alpha › Up-down Bundle › CREB-binding Protein; Chain A › TAZ domain	0.60	22.0	2.80e-01	75.0%	52.9%
3n3dB00	1.10.600.10	Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase	0.58	52.0	4.00e-01	100.0%	96.5%
5b00A00	1.10.600.10	Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase	0.57	49.0	4.02e-01	96.3%	93.9%
3ed5A02	1.10.150.240	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2	0.56	30.0	3.61e-01	76.5%	81.0%
2zy9A03	1.10.357.20	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › SLC41 divalent cation transporters, integral membrane domain	0.55	41.0	3.83e-01	77.9%	92.0%
4okmD00	1.10.600.10	Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase	0.55	48.0	3.69e-01	94.9%	89.3%
1n1bB02	1.10.600.10	Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase	0.54	45.0	3.52e-01	91.9%	92.0%
5k7fA02	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.54	31.0	3.14e-01	82.4%	55.8%
7uzqK01	1.10.3430.10	Mainly Alpha › Orthogonal Bundle › Ammonium transporter fold › Ammonium transporter AmtB like domains	0.53	45.0	3.32e-01	90.4%	92.8%
8h6qD01	1.10.600.10	Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase	0.53	46.0	3.59e-01	95.6%	92.5%
5zzjA02	1.10.600.10	Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase	0.53	45.0	3.47e-01	91.9%	90.1%
3ccgA00	1.10.3210.10	Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432	0.52	38.0	3.47e-01	76.5%	95.8%
3h4cA02	1.10.472.110	Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 ›	0.52	38.0	4.21e-01	89.7%	96.4%
4fm3A00	1.20.1270.390	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 ›	0.52	29.0	3.44e-01	79.4%	78.9%
1grlB01	1.10.560.10	Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain	0.51	40.0	3.37e-01	83.1%	93.0%
1u61A00	1.10.1520.10	Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain	0.51	36.0	3.69e-01	72.1%	92.1%
4uiqB00	1.10.490.10	Mainly Alpha › Orthogonal Bundle › Globin-like › Globins	0.50	38.0	3.71e-01	80.1%	96.1%

ECOD (7)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3610989	2498.5.1.0 ↗	mixed a+b and a/b › Zincin-like › GroEL-intermediate domain like › GroEL-intermediate domain like	0.61	36.0	3.90e-01	91.9%	70.0%
4983401	3352.1.1.0 ↗	alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain	0.59	52.0	3.86e-01	97.1%	78.9%
3668440	141.1.1.0 ↗	alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases	0.54	46.0	3.67e-01	93.4%	88.9%
3460196	5106.1.1.0 ↗	extended segments › PetG subunit of the cytochrome b6f complex › PetG subunit of the cytochrome b6f complex › PetG subunit of the cytochrome b6f complex	0.53	39.0	3.67e-01	95.6%	61.2%
3626908	5067.1.1.29 ↗	alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › NPC1_MLD	0.52	42.0	2.71e-01	87.5%	18.5%
3936743	5067.1.1.0 ↗	alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain	0.51	42.0	3.53e-01	88.2%	54.0%
3732736	5067.1.1.0 ↗	alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain	0.50	41.0	3.43e-01	88.2%	56.7%

D3 medium residues 983-1102

PDB

Domain cluster: representative

CATH (65)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4dciA00	6.10.140.1110	Special › Helix non-globular › Helix Hairpins ›	0.76	51.0	4.74e-01	97.5%	55.8%
3s84A02	1.20.120.20	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein	0.75	59.0	5.29e-01	95.8%	61.8%
4akvA02	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.72	52.0	4.39e-01	99.2%	46.3%
4wpeA00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.71	55.0	4.13e-01	100.0%	34.9%
7dluA01	1.10.287.1260	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.71	42.0	4.43e-01	100.0%	65.7%
1htmD00	3.90.20.10	Alpha Beta › Alpha-Beta Complex › Hemagglutinin Ectodomain; Chain B ›	0.70	53.0	5.26e-01	90.8%	76.4%
1t72A01	1.20.58.220	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2	0.70	44.0	4.50e-01	90.0%	64.1%
4lwsA00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.70	46.0	5.06e-01	93.3%	81.0%
1sziA02	1.20.120.340	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS	0.69	58.0	5.53e-01	90.0%	99.3%
2ot4A03	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.68	42.0	4.48e-01	86.7%	69.2%
3tbiB02	6.10.140.1670	Special › Helix non-globular › Helix Hairpins ›	0.68	53.0	5.77e-01	95.8%	96.0%
2rdcA00	1.10.287.800	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242	0.68	42.0	4.11e-01	90.0%	56.4%
4egwA02	1.20.58.340	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region	0.67	44.0	4.42e-01	87.5%	65.5%
1uruA01	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.66	53.0	4.35e-01	100.0%	47.8%
1l8dA00	1.10.287.510	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.66	50.0	5.35e-01	98.3%	92.2%
7utzR02	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.66	45.0	3.42e-01	90.8%	30.4%
3qa8A04	1.20.1270.250	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 ›	0.66	49.0	3.97e-01	99.2%	40.3%
3fd0A01	3.90.1150.60	Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Methioning gamme-lyase, C-terminal domain	0.66	43.0	3.63e-01	85.0%	40.9%
3nb0B03	6.10.260.10	Special › Helix non-globular › F1FO ATP Synthase ›	0.66	41.0	4.90e-01	88.3%	90.5%
1fxkB00	1.10.287.370	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.66	52.0	5.46e-01	93.3%	91.7%
3favD00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.66	42.0	5.02e-01	86.7%	100.0%
4k0dA00	1.20.120.1730	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.65	53.0	5.04e-01	87.5%	96.5%
1wcrA00	1.20.58.80	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit	0.65	40.0	4.30e-01	90.0%	70.9%
1ydxA02	1.10.287.1120	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein	0.65	46.0	5.14e-01	95.0%	96.7%
2rd0B00	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.65	49.0	4.66e-01	100.0%	67.6%
2oduA02	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.65	41.0	4.34e-01	84.2%	71.4%
3pwxA01	1.20.1330.10	Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain	0.65	56.0	4.91e-01	96.7%	92.9%
3i2wA01	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.65	51.0	3.95e-01	100.0%	38.8%
1e2aA00	1.20.58.80	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit	0.64	38.0	4.09e-01	80.0%	67.6%
2yevA03	1.20.120.80	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle	0.64	42.0	3.65e-01	86.7%	43.5%
4h63H01	1.20.58.1710	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.64	38.0	4.76e-01	80.0%	98.6%
4dylA02	1.10.287.160	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat	0.63	47.0	5.17e-01	98.3%	97.9%
4nqiD00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.63	53.0	4.21e-01	100.0%	46.1%
4ke2A00	6.10.140.1860	Special › Helix non-globular › Helix Hairpins ›	0.63	58.0	4.87e-01	100.0%	60.7%
1m5iA00	1.10.287.450	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.62	48.0	5.13e-01	92.5%	92.4%
3aeiA00	1.10.287.370	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.61	44.0	4.88e-01	91.7%	95.7%
2ch7A00	1.10.287.950	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein	0.61	56.0	4.12e-01	100.0%	86.4%
2zdiB00	1.10.287.370	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.61	47.0	4.98e-01	97.5%	93.4%
1hciA01	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.61	43.0	4.28e-01	90.8%	69.0%
1qu7A00	1.10.287.950	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein	0.60	56.0	4.48e-01	100.0%	52.9%
4mh6A00	1.10.287.1700	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.60	56.0	5.06e-01	100.0%	86.2%
4fzsA00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.60	51.0	4.17e-01	94.2%	51.7%
8a1gC01	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.60	54.0	4.74e-01	100.0%	67.4%
4cgkA01	6.10.250.3150	Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces ›	0.59	53.0	4.39e-01	98.3%	72.4%
4ijjB00	1.20.120.910	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain	0.59	44.0	4.29e-01	94.2%	71.5%
7yu4A01	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.59	46.0	3.65e-01	84.2%	81.3%
8i3jA01	1.20.920.20	Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A ›	0.59	51.0	4.02e-01	95.8%	68.1%
1fxkC00	1.10.287.370	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.59	52.0	5.09e-01	98.3%	91.0%
3aonA00	1.10.287.3240	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.58	46.0	4.00e-01	85.0%	91.5%
1wdzA00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.58	53.0	4.25e-01	100.0%	51.9%
3vkgA12	1.10.287.2610	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.58	53.0	4.33e-01	100.0%	75.8%
3errA01	1.20.920.60	Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A ›	0.56	49.0	4.15e-01	98.3%	79.3%
2xubA05	6.10.140.1450	Special › Helix non-globular › Helix Hairpins ›	0.55	42.0	4.68e-01	86.7%	100.0%
6vq6H01	1.10.287.3240	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.55	50.0	4.18e-01	100.0%	81.4%
2b5uA02	1.10.287.620	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins	0.55	49.0	4.51e-01	100.0%	75.8%
1fioA00	1.20.58.70	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.54	49.0	4.18e-01	98.3%	98.9%
3pltA00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.54	49.0	4.02e-01	100.0%	58.4%
1qgiA01	3.30.386.10	Alpha Beta › 2-Layer Sandwich › Chitosanase; Chain A, domain 2 › Chitosanase, subunit A, domain 2	0.53	36.0	3.46e-01	70.0%	91.2%
6q45G01	1.10.287.80	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain	0.53	46.0	4.35e-01	99.2%	78.8%
1g8xA06	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.53	48.0	3.51e-01	100.0%	46.7%
2yqyA00	1.20.120.450	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain	0.52	42.0	4.19e-01	85.0%	81.7%
2nnwA02	1.10.287.4070	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.52	42.0	4.14e-01	86.7%	100.0%
4hz4A02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.51	35.0	3.68e-01	70.8%	91.1%
3spcA02	1.10.287.70	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.51	43.0	4.28e-01	90.0%	87.4%
2etdA00	1.20.1440.20	Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain	0.51	43.0	4.09e-01	91.7%	90.1%

ECOD (75)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3729252	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.77	55.0	5.67e-01	100.0%	76.5%
3662019	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.73	48.0	4.46e-01	89.2%	54.5%
4025636	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.73	57.0	5.17e-01	100.0%	62.0%
3712573	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.72	59.0	5.53e-01	98.3%	72.1%
3739779	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.72	56.0	4.75e-01	100.0%	51.9%
3168735	4177.1.1.9 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Snx8_BAR_dom	0.70	55.0	4.18e-01	100.0%	37.0%
3731644	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.70	52.0	4.59e-01	100.0%	54.7%
3699465	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.69	54.0	5.05e-01	100.0%	66.0%
3494796	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.69	55.0	4.17e-01	100.0%	37.0%
3772767	5086.1.1.87 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING	0.69	50.0	4.94e-01	98.3%	71.2%
None	—		0.69	42.0	3.55e-01	92.5%	36.5%
3553813	3291.1.1.82 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › ING	0.69	49.0	4.91e-01	98.3%	71.2%
3225405	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.68	51.0	4.85e-01	100.0%	66.4%
3557114	604.1.1.66 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_1st_PEPL	0.68	44.0	4.60e-01	86.7%	70.9%
3995294	1065.1.1.0 ↗	alpha bundles › SPX domain › SPX domain › SPX domain	0.67	48.0	4.73e-01	90.0%	69.6%
3786359	3291.1.1.0 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related	0.67	49.0	5.31e-01	98.3%	92.0%
3830963	603.1.1.100 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017	0.67	44.0	4.45e-01	98.3%	66.7%
3812652	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.66	55.0	4.62e-01	100.0%	53.8%
3969049	601.4.1.3 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › 4HB_MCP_1	0.66	59.0	5.32e-01	98.3%	96.4%
3949246	601.4.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains	0.66	57.0	5.11e-01	94.2%	98.2%
3673003	3922.1.1.254 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › NET2A_C	0.66	48.0	4.79e-01	93.3%	72.8%
4142346	5086.1.1.87 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING	0.66	49.0	5.09e-01	98.3%	84.5%
3795092	622.4.1.0 ↗	alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related	0.65	45.0	4.32e-01	93.3%	62.2%
5047149	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.65	47.0	4.15e-01	95.0%	51.8%
4018889	2004.1.1.481 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_29	0.64	47.0	3.14e-01	95.8%	20.4%
3465146	2004.1.1.250 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd	0.63	50.0	3.24e-01	84.2%	66.5%
5015079	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.63	43.0	2.90e-01	70.0%	34.7%
3973695	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.62	53.0	4.50e-01	100.0%	57.4%
3526138	5054.1.1.2 ↗	alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans	0.62	51.0	3.85e-01	90.0%	94.8%
3515340	601.3.1.16 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Cornichon	0.62	49.0	4.60e-01	84.2%	96.6%
5027935	603.1.1.0 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins	0.61	42.0	3.96e-01	93.3%	57.2%
3680007	3755.3.1.549 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PF28649	0.61	56.0	5.49e-01	100.0%	93.1%
5060002	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.60	56.0	4.87e-01	99.2%	88.0%
4057653	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.60	56.0	4.22e-01	100.0%	52.0%
4010416	1.1.7.0 ↗	beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C	0.60	53.0	5.32e-01	98.3%	92.8%
3594185	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.60	48.0	4.04e-01	98.3%	50.7%
3920552	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.59	48.0	4.01e-01	99.2%	49.5%
3961938	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.59	54.0	4.57e-01	100.0%	61.0%
3899656	3758.1.1.0 ↗	alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins	0.59	51.0	3.79e-01	95.0%	37.1%
3385968	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.59	45.0	3.85e-01	98.3%	49.0%
4974110	3755.4.1.91 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › DUF7121	0.59	51.0	4.13e-01	98.3%	49.6%
3973283	325.1.7.27 ↗	a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › HH_AprE	0.58	53.0	4.47e-01	100.0%	60.5%
3715936	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.58	53.0	4.68e-01	100.0%	77.7%
3168493	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.58	51.0	4.57e-01	100.0%	69.1%
4523639	5086.1.1.92 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE	0.58	53.0	4.52e-01	100.0%	62.6%
3740490	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.58	52.0	4.22e-01	99.2%	82.2%
3414469	109.4.1.1360 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CBF, NOC3p	0.58	43.0	2.71e-01	77.5%	34.6%
3627942	3755.4.1.1 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PI3K_P85_iSH2	0.58	53.0	4.63e-01	99.2%	73.7%
3336964	3291.1.1.0 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related	0.57	45.0	3.56e-01	95.8%	39.6%
3235839	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.57	52.0	4.61e-01	100.0%	78.9%
3632884	5050.1.1.9 ↗	alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1	0.57	44.0	3.72e-01	81.7%	62.9%
3707204	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.57	53.0	3.91e-01	99.2%	49.5%
4969435	633.5.1.1 ↗	alpha bundles › Bromodomain-like › LemA-like › LemA-like › LemA	0.57	51.0	4.57e-01	99.2%	86.5%
3954485	3755.1.1.0 ↗	alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related	0.56	48.0	4.30e-01	93.3%	92.4%
3273862	192.2.1.0 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin	0.56	40.0	4.38e-01	85.8%	92.6%
3605145	603.1.1.97 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE	0.56	52.0	4.04e-01	100.0%	82.8%
3306934	632.1.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain	0.56	37.0	3.88e-01	86.7%	74.5%
3309050	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.56	45.0	3.97e-01	85.0%	63.5%
3934585	3755.3.1.465 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A	0.55	48.0	4.47e-01	93.3%	90.7%
3716333	603.1.1.1 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin	0.55	51.0	4.15e-01	100.0%	97.2%
3944338	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.55	49.0	4.94e-01	98.3%	97.5%
3586290	601.44.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in anaphase-promoting complex subunit 4 › Helical bundle domain in anaphase-promoting complex subunit 4 › ANAPC4	0.55	48.0	3.93e-01	96.7%	53.8%
4629345	3755.2.1.0 ↗	alpha bundles › YscO-like › Flagellar FliJ protein › Flagellar FliJ protein	0.54	48.0	4.30e-01	100.0%	90.9%
4535441	192.2.1.0 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin	0.54	48.0	4.21e-01	99.2%	86.7%
4480624	601.50.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Flagellar cap protein FliD helical bundle domain › Flagellar cap protein FliD helical bundle domain	0.54	42.0	4.04e-01	83.3%	97.9%
3175351	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.54	49.0	4.53e-01	100.0%	81.3%
4453346	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.53	46.0	3.47e-01	93.3%	93.4%
3538350	3755.1.1.0 ↗	alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related	0.53	47.0	4.60e-01	99.2%	98.5%
4937016	3939.1.1.0 ↗	alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain	0.53	45.0	4.03e-01	91.7%	97.6%
4950969	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.52	47.0	3.17e-01	100.0%	84.9%
3289134	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.52	46.0	4.05e-01	100.0%	85.4%
5042372	5054.1.1.8 ↗	alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2	0.52	41.0	4.42e-01	89.2%	97.1%
4949100	3926.1.1.1 ↗	alpha bundles › V-type proton ATPase subunit D › V-type proton ATPase subunit D › V-type proton ATPase subunit D › ATP-synt_D	0.51	46.0	4.18e-01	100.0%	82.3%
3852419	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.51	45.0	3.81e-01	99.2%	58.0%
3685980	5059.1.1.0 ↗	alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter	0.51	34.0	2.85e-01	85.0%	42.6%

D4 medium residues 1103-1206

PDB

Domain cluster: representative

CATH (52)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1k04A02	1.20.120.330	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2	0.93	63.0	6.37e-01	76.9%	69.2%
3a8pA02	6.10.140.680	Special › Helix non-globular › Helix Hairpins ›	0.93	62.0	6.04e-01	71.2%	62.3%
4l0rB00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.91	60.0	7.12e-01	70.2%	95.9%
2gd5A00	6.10.140.1230	Special › Helix non-globular › Helix Hairpins ›	0.90	73.0	6.46e-01	84.6%	93.7%
4ijjB00	1.20.120.910	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain	0.89	58.0	5.32e-01	73.1%	53.1%
1fioA00	1.20.58.70	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.89	60.0	4.78e-01	73.1%	37.9%
4mh6A00	1.10.287.1700	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.88	83.0	7.01e-01	99.0%	84.3%
3na7A00	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.87	75.0	5.60e-01	96.2%	40.1%
2ch7A00	1.10.287.950	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein	0.87	78.0	5.36e-01	94.2%	32.0%
2ke4A00	6.10.140.470	Special › Helix non-globular › Helix Hairpins ›	0.87	65.0	6.75e-01	82.7%	82.7%
7p3rA01	1.20.1170.10	Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; ›	0.86	74.0	5.03e-01	95.2%	28.9%
4b6xA00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.86	55.0	6.70e-01	70.2%	98.6%
4wpeA00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.85	80.0	5.72e-01	100.0%	44.0%
1qu7A00	1.10.287.950	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein	0.85	76.0	5.76e-01	96.2%	43.6%
3qweA00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.85	79.0	5.75e-01	100.0%	42.3%
7sgrA02	1.20.1560.10	Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain	0.85	69.0	4.78e-01	87.5%	28.7%
1s3qG00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.84	58.0	4.88e-01	71.2%	71.8%
1ydxA02	1.10.287.1120	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein	0.83	59.0	6.39e-01	79.8%	84.4%
3g67A00	1.10.287.950	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein	0.83	75.0	5.77e-01	95.2%	46.5%
3k29A00	1.10.287.1700	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.83	76.0	6.47e-01	98.1%	81.4%
6bl6B01	1.20.1560.10	Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain	0.83	68.0	4.67e-01	87.5%	28.2%
1ciiA01	1.20.250.10	Mainly Alpha › Up-down Bundle › Colicin Ia; domain 1 › Colicin Ia, domain 1	0.83	77.0	5.22e-01	100.0%	55.2%
2rd0B00	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.82	69.0	6.20e-01	98.1%	66.2%
1cunA01	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.82	53.0	5.38e-01	73.1%	66.7%
1x04A00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.82	76.0	6.00e-01	100.0%	53.5%
7aalA01	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.81	73.0	5.33e-01	99.0%	38.3%
3vkgA12	1.10.287.2610	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.80	74.0	5.72e-01	100.0%	47.9%
6grjB01	1.20.1170.10	Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; ›	0.80	75.0	5.20e-01	100.0%	34.0%
3tulB00	1.20.120.330	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2	0.80	59.0	5.41e-01	87.5%	60.2%
4lwsA00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.80	67.0	6.85e-01	89.4%	94.0%
6q45G01	1.10.287.80	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain	0.79	71.0	6.22e-01	95.2%	84.2%
1a36A04	1.10.132.10	Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 ›	0.79	54.0	4.50e-01	71.2%	41.7%
5y06A01	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.78	65.0	5.01e-01	100.0%	41.0%
6xj1A01	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.78	68.0	5.09e-01	100.0%	40.0%
4q4hB01	1.20.1560.10	Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain	0.77	69.0	4.75e-01	96.2%	92.2%
2rdcA00	1.10.287.800	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242	0.77	53.0	4.90e-01	71.2%	56.4%
1s35A02	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.77	50.0	4.94e-01	73.1%	62.7%
3r84B00	6.10.280.160	Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22	0.76	56.0	6.31e-01	77.9%	98.8%
4nqiD00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.76	65.0	4.93e-01	91.3%	46.1%
1fewA00	1.20.58.70	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.76	59.0	4.96e-01	83.7%	49.7%
1h7cA00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.76	55.0	5.52e-01	76.0%	75.7%
6tqfA01	1.20.1560.10	Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain	0.75	65.0	4.39e-01	100.0%	25.3%
3fb2A01	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.75	49.0	4.93e-01	74.0%	65.7%
3nymA00	6.10.290.10	Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.74	55.0	5.18e-01	76.9%	79.8%
4aflA00	6.10.140.1740	Special › Helix non-globular › Helix Hairpins ›	0.74	56.0	5.69e-01	79.8%	80.4%
1wa8A00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.74	50.0	5.15e-01	70.2%	72.7%
3pltA00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.74	65.0	5.09e-01	100.0%	46.7%
3i2wA01	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.73	64.0	4.73e-01	95.2%	38.8%
2v0oB00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.72	64.0	4.74e-01	100.0%	37.6%
2e9xA01	1.20.58.1030	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.72	52.0	4.88e-01	76.0%	60.9%
4v1gA00	1.20.20.10	Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C	0.69	48.0	5.21e-01	71.2%	91.8%
3agtA00	1.20.120.50	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like	0.62	43.0	3.96e-01	71.2%	89.5%

ECOD (90)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3738041	192.5.1.1 ↗	alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1	0.94	63.0	7.00e-01	72.1%	83.5%
3273862	192.2.1.0 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin	0.93	67.0	7.04e-01	76.9%	81.1%
3559003	192.2.1.1 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2	0.92	72.0	7.39e-01	85.6%	84.0%
5031890	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.90	81.0	5.94e-01	94.2%	40.0%
3425296	3291.1.1.0 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related	0.90	62.0	5.55e-01	70.2%	54.1%
3611804	5086.1.1.102 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PTHB1_hp	0.89	70.0	6.44e-01	82.7%	65.4%
3719459	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.89	85.0	6.76e-01	100.0%	60.0%
4386662	3291.1.1.158 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Seryl_tRNA_N	0.88	63.0	6.07e-01	76.0%	66.1%
4406698	192.2.1.0 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin	0.88	65.0	6.82e-01	79.8%	83.2%
3477269	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.88	83.0	7.10e-01	99.0%	69.0%
3627942	3755.4.1.1 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PI3K_P85_iSH2	0.88	79.0	6.46e-01	99.0%	56.0%
4514051	192.7.1.2 ↗	alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N	0.88	62.0	6.03e-01	76.0%	66.1%
4988623	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.88	78.0	5.63e-01	99.0%	37.0%
4007316	3291.1.1.4 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30	0.87	79.0	6.79e-01	99.0%	65.2%
3269590	3291.1.1.0 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related	0.87	68.0	6.51e-01	80.8%	73.9%
3346133	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.87	75.0	5.70e-01	99.0%	43.7%
4939828	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.86	77.0	5.22e-01	100.0%	29.3%
1171038	3755.3.1.148 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › CT398_CC	0.86	75.0	5.98e-01	96.2%	49.7%
3732919	3755.3.1.46 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › She9_MDM33	0.86	77.0	6.14e-01	95.2%	51.6%
4974450	3291.1.1.4 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30	0.86	77.0	6.34e-01	98.1%	56.6%
3536875	4177.1.1.1 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH	0.85	77.0	5.51e-01	99.0%	35.4%
3615982	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.85	77.0	5.18e-01	95.2%	30.3%
3929349	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.85	68.0	5.33e-01	86.5%	42.4%
3908626	3755.3.1.483 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PF30493	0.85	79.0	5.81e-01	100.0%	55.7%
3712648	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.85	79.0	6.30e-01	99.0%	58.9%
4031283	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.85	79.0	6.90e-01	100.0%	77.3%
4944766	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.85	77.0	5.99e-01	98.1%	48.8%
4024002	3291.1.1.1 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7	0.84	73.0	5.98e-01	91.3%	53.7%
4002750	5086.1.1.118 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › BBS2_hp	0.84	67.0	6.12e-01	83.7%	66.2%
4985494	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.84	77.0	4.85e-01	98.1%	21.3%
3709193	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.84	77.0	5.48e-01	100.0%	36.4%
3412574	3291.1.1.82 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › ING	0.84	71.0	6.50e-01	90.4%	70.8%
3489648	3291.1.1.1 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7	0.84	75.0	6.61e-01	94.2%	68.3%
3187178	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.84	73.0	5.77e-01	92.3%	48.7%
3170139	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.84	62.0	5.29e-01	77.9%	51.0%
4973840	4323.1.1.0 ↗	alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C	0.84	60.0	5.23e-01	73.1%	53.1%
4963794	3755.4.1.90 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PspA_IM30	0.84	77.0	6.54e-01	99.0%	63.7%
5054861	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.83	77.0	4.85e-01	98.1%	23.2%
3695585	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.83	77.0	6.08e-01	100.0%	62.9%
3895215	4177.1.1.5 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5	0.83	77.0	5.93e-01	99.0%	49.3%
3877882	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.83	76.0	5.62e-01	99.0%	41.2%
None	—		0.83	66.0	6.06e-01	83.7%	66.2%
4956941	3291.1.1.4 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30	0.83	75.0	6.06e-01	98.1%	53.2%
5018814	3755.3.1.633 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PspA_IM30	0.82	75.0	6.00e-01	99.0%	52.3%
3696922	3291.1.1.1 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7	0.82	72.0	6.29e-01	94.2%	64.7%
4520774	3291.1.1.4 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30	0.82	77.0	5.96e-01	100.0%	69.0%
4950969	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.82	72.0	4.60e-01	94.2%	27.7%
None	—		0.82	73.0	5.31e-01	100.0%	36.5%
3599997	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.82	76.0	4.37e-01	99.0%	76.4%
3781506	3291.1.1.0 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related	0.82	75.0	6.49e-01	100.0%	66.5%
4226755	2004.1.1.782 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23, AAA_29, SbcC_Walker_B	0.82	72.0	4.59e-01	95.2%	21.1%
3595707	5086.1.1.118 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › BBS2_hp	0.82	65.0	6.03e-01	86.5%	66.9%
4001188	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.81	77.0	4.89e-01	100.0%	30.8%
4015178	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.81	75.0	6.45e-01	99.0%	67.1%
4072295	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.81	75.0	4.94e-01	100.0%	26.3%
3585148	4177.1.1.5 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5	0.81	74.0	5.68e-01	99.0%	46.6%
3560590	3755.3.1.142 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › FAM186A-B_C	0.81	68.0	5.93e-01	90.4%	62.0%
3315414	3291.1.1.0 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related	0.80	73.0	6.01e-01	100.0%	57.2%
3825161	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.80	73.0	5.36e-01	99.0%	40.4%
3960197	3291.1.1.4 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30	0.80	72.0	5.62e-01	100.0%	47.4%
3894262	4177.1.1.1 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH	0.79	73.0	5.14e-01	100.0%	40.7%
5047072	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.79	70.0	6.00e-01	94.2%	69.4%
3239667	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.79	71.0	4.26e-01	100.0%	14.5%
3246381	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.79	68.0	6.15e-01	97.1%	69.3%
3630220	3755.3.1.103 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Golgin_A5	0.79	68.0	5.41e-01	91.3%	99.5%
3788782	2004.1.1.199 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23,SbcC_Walker_B	0.79	71.0	4.42e-01	96.2%	50.7%
5036205	2004.1.1.348 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SbcC_Walker_B	0.78	72.0	4.22e-01	99.0%	46.9%
4117257	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.78	71.0	5.02e-01	99.0%	85.7%
4809272	3291.1.1.4 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30	0.78	66.0	6.30e-01	91.3%	81.0%
3574255	5086.1.1.87 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING	0.78	66.0	6.05e-01	91.3%	70.4%
4515899	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.78	59.0	4.93e-01	78.8%	65.9%
3239971	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.78	66.0	5.07e-01	92.3%	59.1%
3928718	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.77	70.0	6.36e-01	100.0%	75.0%
4345017	2004.1.1.433 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23	0.77	68.0	4.15e-01	96.2%	21.0%
3318681	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.77	70.0	5.01e-01	98.1%	42.5%
4086322	5086.1.1.205 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PF30209	0.77	69.0	5.85e-01	97.1%	86.1%
3837815	2004.1.1.433 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23	0.76	64.0	3.86e-01	90.4%	14.4%
3937673	4177.1.1.1 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH	0.76	69.0	4.75e-01	98.1%	37.6%
3831567	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.76	68.0	5.79e-01	100.0%	81.8%
4862474	3291.1.1.4 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30	0.76	63.0	5.73e-01	94.2%	66.9%
4414254	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.76	64.0	4.62e-01	91.3%	33.9%
3920715	2004.1.1.674 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_21, AAA_23, SbcC_Walker_B	0.75	69.0	4.36e-01	100.0%	39.8%
3292425	3291.1.1.4 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30	0.75	67.0	5.34e-01	100.0%	49.8%
3607135	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.74	66.0	6.07e-01	98.1%	74.8%
4018104	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.73	63.0	4.53e-01	98.1%	33.2%
3599499	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.73	64.0	5.71e-01	100.0%	68.0%
3692994	2004.1.1.73 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1	0.70	60.0	4.25e-01	91.3%	32.5%
3628737	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.70	64.0	4.86e-01	100.0%	43.8%
3268736	2004.1.1.433 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23	0.68	60.0	3.89e-01	100.0%	20.4%
3746558	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.64	52.0	4.10e-01	86.5%	59.0%

D5 medium residues 1207-1282

PDB

Domain cluster: representative

CATH (75)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4q20A01	1.10.287.130	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain	0.89	61.0	5.95e-01	80.3%	65.9%
4b6xA00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.82	60.0	6.30e-01	80.3%	84.1%
3fd9A03	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.82	63.0	6.41e-01	78.9%	86.3%
3b2eF00	1.10.287.660	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.82	60.0	6.54e-01	78.9%	93.5%
1grjA01	1.10.287.180	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain	0.82	60.0	6.11e-01	76.3%	81.1%
3r84B00	6.10.280.160	Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22	0.81	62.0	6.12e-01	80.3%	90.0%
1gqeA01	1.20.58.410	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor	0.81	59.0	5.08e-01	76.3%	81.4%
1m5iA00	1.10.287.450	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.80	61.0	5.37e-01	85.5%	57.1%
3sjqC00	1.10.287.70	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.80	59.0	5.86e-01	78.9%	73.8%
4ijjB00	1.20.120.910	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain	0.80	61.0	5.02e-01	80.3%	51.5%
3lssA01	1.10.287.40	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain	0.80	61.0	5.29e-01	80.3%	88.4%
3g67A00	1.10.287.950	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein	0.80	60.0	4.25e-01	78.9%	28.6%
2ch7A00	1.10.287.950	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein	0.79	60.0	3.90e-01	80.3%	20.4%
4k0dA00	1.20.120.1730	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.78	58.0	4.61e-01	77.6%	88.8%
3iq1B00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.78	64.0	5.01e-01	89.5%	81.1%
3pltA00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.77	58.0	4.11e-01	78.9%	40.7%
2lf0A01	4.10.860.10	Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain	0.77	56.0	6.20e-01	78.9%	96.7%
2b5uA02	1.10.287.620	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins	0.77	58.0	4.52e-01	80.3%	39.8%
1wleA01	1.10.287.40	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain	0.77	59.0	5.10e-01	80.3%	57.9%
1z0pA00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.76	60.0	6.14e-01	82.9%	98.6%
5jrcA00	1.20.58.2140	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.75	65.0	4.81e-01	100.0%	38.2%
4xvxA03	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.75	59.0	4.74e-01	84.2%	49.7%
2fcwA00	1.20.81.10	Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain	0.75	56.0	5.05e-01	80.3%	84.0%
5k3hB04	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.75	56.0	4.60e-01	80.3%	45.1%
3tulB00	1.20.120.330	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2	0.74	56.0	4.62e-01	80.3%	74.4%
1x04A00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.74	55.0	4.07e-01	80.3%	70.5%
1wcrA00	1.20.58.80	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit	0.74	66.0	5.94e-01	98.7%	80.6%
2fupA00	1.20.58.300	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like	0.73	68.0	5.64e-01	100.0%	78.7%
2odmA00	1.10.287.750	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like	0.73	60.0	5.95e-01	98.7%	86.1%
3r2kA00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.73	61.0	4.88e-01	93.4%	77.9%
4ioeA00	1.10.287.850	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain	0.73	55.0	5.28e-01	80.3%	70.1%
1lb3A00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.73	62.0	4.77e-01	98.7%	42.5%
3ay5A01	1.20.1420.10	Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain	0.72	64.0	5.33e-01	98.7%	75.9%
3r2qA02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.72	66.0	5.72e-01	100.0%	73.5%
1a36A04	1.10.132.10	Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 ›	0.72	54.0	4.13e-01	80.3%	40.6%
1s3qG00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.72	63.0	4.83e-01	98.7%	44.2%
4nswB01	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.72	54.0	3.72e-01	80.3%	60.5%
4agsB04	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.72	62.0	5.23e-01	100.0%	56.4%
5nx5B00	1.10.600.10	Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase	0.72	52.0	3.49e-01	80.3%	20.2%
2ic6A00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.71	51.0	5.28e-01	80.3%	81.7%
2i0mA01	1.20.58.220	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2	0.71	65.0	5.76e-01	100.0%	79.2%
1b5lA00	1.20.1250.10	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; ›	0.71	51.0	4.04e-01	75.0%	100.0%
4iu9B02	1.20.1250.20	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains	0.71	63.0	4.60e-01	97.4%	89.7%
3l8rA00	1.20.58.80	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit	0.71	64.0	5.82e-01	100.0%	83.3%
1wa8A00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.71	53.0	4.88e-01	80.3%	69.7%
2cmrA00	1.20.58.1860	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.71	60.0	4.43e-01	92.1%	46.9%
2clbA01	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.70	57.0	4.51e-01	89.5%	86.2%
1ku9A02	1.10.287.450	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.69	52.0	5.53e-01	80.3%	95.3%
1fewA00	1.20.58.70	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.69	61.0	4.71e-01	100.0%	67.6%
4i17A00	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.69	61.0	4.30e-01	100.0%	33.0%
3v5uA01	6.10.280.80	Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region	0.69	49.0	4.95e-01	75.0%	88.2%
1lvfB00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.69	61.0	5.50e-01	98.7%	89.4%
1otkA00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.68	61.0	4.28e-01	100.0%	96.7%
3nrxA00	1.20.58.1520	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.68	60.0	5.15e-01	98.7%	69.9%
3t5vA00	1.25.40.990	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat ›	0.68	58.0	3.87e-01	93.4%	83.6%
3rq9A00	1.10.287.2500	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.68	57.0	5.68e-01	93.4%	92.3%
4errB00	1.20.58.1190	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.67	50.0	4.88e-01	78.9%	84.3%
3hhcC00	1.20.1250.60	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interferon lambda	0.67	53.0	4.18e-01	96.1%	42.4%
4rm7A03	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.67	53.0	4.33e-01	85.5%	93.5%
1vcsA00	1.20.58.400	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins	0.67	57.0	5.20e-01	94.7%	76.5%
4oydB00	1.10.132.20	Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor	0.66	57.0	4.97e-01	96.1%	83.8%
1kfdA02	1.20.1060.10	Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4	0.66	46.0	4.80e-01	75.0%	80.3%
3favD00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.66	50.0	4.95e-01	80.3%	96.2%
4hz4A02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.65	56.0	5.01e-01	98.7%	73.2%
2b1eA04	1.20.1280.170	Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70	0.64	57.0	4.86e-01	100.0%	63.8%
1to9A00	1.20.910.10	Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like	0.64	55.0	3.97e-01	97.4%	34.2%
6zhiB02	1.20.1270.10	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 ›	0.63	44.0	4.35e-01	76.3%	67.5%
1tj7A01	1.10.275.10	Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain)	0.63	41.0	3.75e-01	72.4%	48.6%
5dkoA02	1.10.3900.10	Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like	0.63	56.0	4.26e-01	97.4%	94.0%
3h3mA00	1.20.58.380	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit.	0.62	53.0	5.03e-01	98.7%	79.8%
4cqiA00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.61	52.0	4.69e-01	97.4%	90.7%
2kg7B00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.61	45.0	4.18e-01	80.3%	67.0%
1gpjA03	1.10.1200.70	Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Glutamyl tRNA-reductase dimerization domain	0.60	45.0	4.40e-01	80.3%	72.9%
3oqlC00	1.20.910.10	Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like	0.56	47.0	3.34e-01	96.1%	35.1%
2oocB00	1.20.120.160	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain	0.52	44.0	4.05e-01	97.4%	78.1%

ECOD (69)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3877882	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.87	66.0	4.43e-01	80.3%	24.5%
3608554	3291.1.1.1 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7	0.85	66.0	5.14e-01	80.3%	48.3%
5079565	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.85	65.0	4.82e-01	80.3%	88.0%
4051951	605.2.1.0 ↗	alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63	0.84	63.0	5.96e-01	78.9%	82.2%
5062668	3755.1.1.0 ↗	alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related	0.83	64.0	5.31e-01	80.3%	80.0%
3949413	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.83	60.0	4.93e-01	92.1%	43.0%
4177204	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.82	63.0	4.39e-01	80.3%	37.3%
3966368	603.5.1.0 ↗	alpha bundles › STAT-like › FlgN-like › FlgN-like	0.82	71.0	6.05e-01	92.1%	81.7%
3592972	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.82	63.0	4.52e-01	80.3%	37.4%
4022925	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.81	62.0	4.40e-01	80.3%	62.4%
3788489	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.81	62.0	4.36e-01	80.3%	71.0%
5024408	3755.3.1.637 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121	0.81	61.0	4.46e-01	80.3%	32.4%
3337008	192.2.1.60 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › KIF21A_4th	0.80	61.0	4.89e-01	80.3%	45.0%
3944950	605.1.1.0 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase	0.80	60.0	6.44e-01	78.9%	96.9%
4471073	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.80	61.0	3.82e-01	80.3%	17.0%
3316949	4006.1.1.0 ↗	alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain	0.79	60.0	4.90e-01	80.3%	70.4%
4652719	3291.1.1.0 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related	0.79	60.0	5.54e-01	80.3%	66.3%
3923558	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.78	60.0	4.41e-01	80.3%	90.8%
3330826	6155.1.1.1 ↗	alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv	0.78	67.0	6.27e-01	96.1%	77.8%
4457403	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.77	59.0	3.96e-01	96.1%	22.6%
4949374	616.1.1.0 ↗	alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain	0.77	60.0	6.45e-01	97.4%	96.9%
3196550	1075.4.1.2 ↗	alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane_2	0.77	70.0	4.29e-01	100.0%	73.2%
3931039	1075.4.1.2 ↗	alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane_2	0.77	69.0	4.39e-01	100.0%	84.1%
3606080	605.1.1.0 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase	0.76	66.0	5.86e-01	97.4%	75.5%
4467862	603.5.1.0 ↗	alpha bundles › STAT-like › FlgN-like › FlgN-like	0.75	70.0	5.55e-01	100.0%	74.5%
2600	101.1.2.14 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_5	0.75	54.0	4.29e-01	76.3%	43.0%
4569731	604.5.1.0 ↗	alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895)	0.75	63.0	4.58e-01	93.4%	94.3%
4976948	4323.1.1.0 ↗	alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C	0.74	59.0	4.81e-01	85.5%	89.3%
3598199	3755.1.1.0 ↗	alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related	0.74	55.0	4.13e-01	78.9%	37.8%
3970019	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.74	56.0	3.91e-01	80.3%	89.1%
4962406	5050.1.1.9 ↗	alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1	0.73	66.0	4.85e-01	100.0%	69.2%
3922047	5050.1.1.0 ↗	alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter	0.73	64.0	4.49e-01	98.7%	73.2%
3557371	3871.1.1.0 ↗	alpha duplicates or obligate multimers › PHIST › PHIST › PHIST	0.73	65.0	5.12e-01	94.7%	79.3%
3564230	4177.1.1.1 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH	0.73	54.0	3.65e-01	78.9%	23.2%
3941457	1203.1.2.3 ↗	alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › YiaAB	0.73	64.0	5.57e-01	100.0%	69.2%
3933812	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.72	54.0	3.92e-01	80.3%	33.0%
3565534	4177.1.1.2 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR	0.72	55.0	3.80e-01	80.3%	52.2%
3571298	5059.1.1.8 ↗	alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Mg_trans_NIPA	0.72	62.0	4.76e-01	96.1%	49.1%
3284609	603.1.1.0 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins	0.71	61.0	5.86e-01	92.1%	85.9%
4243427	3560.1.1.1 ↗	a+b complex topology › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 › Med8	0.71	63.0	4.84e-01	94.7%	53.8%
3180119	604.5.1.0 ↗	alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895)	0.71	63.0	6.07e-01	96.1%	96.5%
4675002	3755.1.1.0 ↗	alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related	0.71	60.0	4.92e-01	89.5%	90.8%
3259417	603.1.1.0 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins	0.71	65.0	4.72e-01	100.0%	43.0%
5028533	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.71	52.0	4.34e-01	77.6%	46.9%
3951152	150.5.1.11 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › T7SS_ESX_EspC	0.71	52.0	4.76e-01	77.6%	91.0%
2649515	5050.1.1.9 ↗	alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1	0.71	63.0	4.69e-01	100.0%	73.3%
3884665	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.70	63.0	5.14e-01	100.0%	56.4%
4952010	605.1.1.0 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase	0.70	50.0	5.09e-01	75.0%	100.0%
5059236	5059.1.1.0 ↗	alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter	0.70	60.0	5.67e-01	94.7%	80.0%
4469629	3883.1.1.1 ↗	alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf	0.70	62.0	4.79e-01	98.7%	44.8%
3593425	1075.4.1.0 ↗	alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold	0.70	62.0	4.03e-01	100.0%	41.4%
3726168	603.1.1.0 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins	0.70	62.0	5.38e-01	94.7%	70.9%
3589400	192.5.1.4 ↗	alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › DUF1140	0.70	62.0	5.58e-01	94.7%	91.0%
4057957	603.5.1.1 ↗	alpha bundles › STAT-like › FlgN-like › FlgN-like › FlgN	0.70	61.0	5.06e-01	100.0%	72.1%
5020411	601.4.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains	0.70	60.0	4.86e-01	97.4%	75.3%
3535346	2004.1.1.184 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11	0.69	52.0	3.20e-01	80.3%	14.8%
3629399	1075.4.1.2 ↗	alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane_2	0.69	62.0	3.94e-01	97.4%	77.4%
3711300	601.4.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains	0.68	58.0	4.69e-01	97.4%	68.4%
4565043	3718.1.1.0 ↗	alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT	0.68	61.0	5.80e-01	100.0%	91.1%
4015874	3291.1.1.0 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related	0.68	64.0	4.72e-01	100.0%	90.9%
3829773	3684.1.1.2 ↗	alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1	0.66	58.0	4.14e-01	97.4%	73.3%
2576339	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.66	49.0	4.31e-01	80.3%	52.1%
3615307	604.12.1.0 ↗	alpha bundles › Spectrin repeat-like › MIT domain › MIT domain	0.66	53.0	4.99e-01	100.0%	72.6%
3831792	601.1.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin	0.65	55.0	3.90e-01	97.4%	53.3%
3443676	192.29.1.0 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding)	0.65	51.0	4.69e-01	85.5%	69.0%
4580475	3684.1.1.28 ↗	alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PF26154	0.65	55.0	4.71e-01	96.1%	98.4%
3279105	1075.4.1.1 ↗	alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane	0.63	54.0	3.67e-01	100.0%	43.9%
4016436	3324.1.1.1 ↗	extended segments › Helical arch in Ski2-like helicases › Helical arch in Ski2-like helicases › Helical arch in Ski2-like helicases › MTR4_beta-barrel	0.63	54.0	4.76e-01	96.1%	64.5%
4957618	5060.1.1.1 ↗	alpha bundles › V-type ATP synthase subunit C › V-type ATP synthase subunit C › V-type ATP synthase subunit C › vATP-synt_AC39	0.62	50.0	4.47e-01	98.7%	60.5%