←Back to structures
ON456348.1__UTN93013.1__SEA_MARKY_10__00010
Bact-VirON456348.1__UTN93013.1__SEA_MARKY_10__00010
Identity
- Accession:
- ON456348 ↗
- Kingdom:
- phage
Quality
67.1
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 487-570
Domain cluster:
representative
CATH (65)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2qqyA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.90 | 74.0 | 6.09e-01 | 85.7% | 97.8% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.89 | 73.0 | 5.87e-01 | 85.7% | 96.0% |
| 3r84A00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.89 | 64.0 | 6.59e-01 | 75.0% | 90.1% |
| 1jgcA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.88 | 80.0 | 6.31e-01 | 96.4% | 90.6% |
| 2chpA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.88 | 72.0 | 5.82e-01 | 85.7% | 97.3% |
| 3hiuD00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.87 | 82.0 | 6.56e-01 | 100.0% | 98.7% |
| 3r2kA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.87 | 79.0 | 6.30e-01 | 96.4% | 94.2% |
| 2fcwA00 | 1.20.81.10 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain | 0.87 | 63.0 | 5.78e-01 | 75.0% | 59.4% |
| 1zs3A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.87 | 72.0 | 5.54e-01 | 86.9% | 87.1% |
| 1a36A04 | 1.10.132.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.87 | 60.0 | 4.60e-01 | 71.4% | 38.3% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.87 | 58.0 | 5.39e-01 | 76.2% | 57.0% |
| 1wvtA00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.87 | 74.0 | 6.00e-01 | 90.5% | 93.9% |
| 3lssA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.87 | 62.0 | 5.54e-01 | 75.0% | 55.4% |
| 1nfvA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.86 | 78.0 | 6.04e-01 | 96.4% | 86.4% |
| 3iq1B00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.86 | 70.0 | 5.56e-01 | 85.7% | 91.2% |
| 3t9jA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.86 | 69.0 | 5.65e-01 | 84.5% | 100.0% |
| 2v6yA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.86 | 69.0 | 7.31e-01 | 84.5% | 100.0% |
| 4b6xA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.86 | 61.0 | 6.69e-01 | 73.8% | 89.9% |
| 2gs4A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.86 | 78.0 | 6.16e-01 | 96.4% | 98.1% |
| 5fzsA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.86 | 57.0 | 5.24e-01 | 86.9% | 54.2% |
| 4abmD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.85 | 59.0 | 6.16e-01 | 73.8% | 77.9% |
| 3e6sA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.85 | 79.0 | 6.26e-01 | 100.0% | 94.3% |
| 2efkA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.84 | 61.0 | 4.16e-01 | 75.0% | 24.8% |
| 4yvoA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.84 | 59.0 | 5.16e-01 | 77.4% | 51.3% |
| 3unoE00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.83 | 74.0 | 5.83e-01 | 96.4% | 87.4% |
| 2c2uA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.83 | 73.0 | 5.62e-01 | 94.0% | 84.3% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.83 | 59.0 | 5.36e-01 | 72.6% | 68.2% |
| 3ro3A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.83 | 59.0 | 4.69e-01 | 78.6% | 39.0% |
| 4cmyA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.83 | 76.0 | 6.04e-01 | 100.0% | 91.4% |
| 1s3qG00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.83 | 74.0 | 5.90e-01 | 97.6% | 89.6% |
| 1lb3A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.83 | 74.0 | 5.80e-01 | 96.4% | 89.8% |
| 3hr0B01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.83 | 59.0 | 6.07e-01 | 73.8% | 83.5% |
| 1tjoB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.82 | 77.0 | 5.90e-01 | 100.0% | 88.0% |
| 4cybD00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.82 | 74.0 | 5.75e-01 | 96.4% | 89.5% |
| 2vxxA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.82 | 77.0 | 5.93e-01 | 100.0% | 88.4% |
| 2fjcB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.82 | 70.0 | 5.59e-01 | 90.5% | 93.6% |
| 1wleA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.82 | 59.0 | 5.25e-01 | 75.0% | 60.5% |
| 8fbnB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.81 | 74.0 | 5.38e-01 | 100.0% | 38.3% |
| 3kwoA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.81 | 68.0 | 5.53e-01 | 89.3% | 98.0% |
| 7e9uA01 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.81 | 67.0 | 4.16e-01 | 89.3% | 37.2% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.80 | 60.0 | 5.34e-01 | 78.6% | 63.8% |
| 1a7eA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.78 | 60.0 | 5.34e-01 | 81.0% | 61.9% |
| 2jbwA01 | 1.20.1440.110 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase | 0.78 | 60.0 | 5.57e-01 | 81.0% | 69.9% |
| 2katA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.78 | 58.0 | 5.21e-01 | 82.1% | 57.4% |
| 1wfdA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.78 | 67.0 | 6.53e-01 | 94.0% | 90.3% |
| 6d5xA00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.78 | 67.0 | 5.39e-01 | 91.7% | 96.7% |
| 1sr2A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.77 | 55.0 | 4.89e-01 | 76.2% | 53.4% |
| 1elrA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.77 | 54.0 | 4.65e-01 | 78.6% | 47.7% |
| 4xpwA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.76 | 60.0 | 5.16e-01 | 84.5% | 64.9% |
| 2crbA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.76 | 70.0 | 6.65e-01 | 100.0% | 91.8% |
| 1quuA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 68.0 | 5.93e-01 | 100.0% | 90.5% |
| 7powA01 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.75 | 61.0 | 4.65e-01 | 89.3% | 64.1% |
| 3qo8A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.75 | 53.0 | 4.89e-01 | 73.8% | 59.4% |
| 1bgfA00 | 1.10.532.10 | Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain | 0.74 | 52.0 | 4.54e-01 | 72.6% | 54.0% |
| 2ondA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.74 | 62.0 | 4.16e-01 | 90.5% | 34.7% |
| 1fpoC02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.73 | 56.0 | 5.49e-01 | 81.0% | 89.0% |
| 3qc1A01 | 1.25.40.540 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TAP42-like family | 0.73 | 55.0 | 4.56e-01 | 81.0% | 57.0% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.73 | 57.0 | 4.79e-01 | 89.3% | 51.9% |
| 2a9uA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.70 | 61.0 | 5.43e-01 | 100.0% | 74.6% |
| 1yg2A02 | 6.10.140.190 | Special › Helix non-globular › Helix Hairpins › | 0.70 | 49.0 | 4.86e-01 | 75.0% | 68.9% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.69 | 54.0 | 5.16e-01 | 86.9% | 96.1% |
| 2ra1A03 | 1.20.58.770 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 48.0 | 5.26e-01 | 77.4% | 100.0% |
| 2l3lA01 | 1.20.58.1250 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain | 0.67 | 55.0 | 5.11e-01 | 90.5% | 77.4% |
| 3l1nA02 | 1.20.1280.140 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.61 | 45.0 | 4.48e-01 | 77.4% | 93.1% |
| 2hjmA01 | 1.20.120.460 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › protein pf1176 like | 0.61 | 47.0 | 4.69e-01 | 86.9% | 81.4% |
ECOD (66)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5071867 | 150.1.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Ferritin | 0.93 | 78.0 | 6.26e-01 | 88.1% | 91.9% |
| 3385614 | 7516.1.1.2 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 | 0.93 | 66.0 | 4.38e-01 | 73.8% | 21.4% |
| 3405706 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.92 | 76.0 | 6.40e-01 | 86.9% | 62.3% |
| 5031890 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.91 | 66.0 | 4.56e-01 | 75.0% | 25.7% |
| 5078340 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.91 | 72.0 | 7.03e-01 | 82.1% | 84.4% |
| 5045256 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.91 | 71.0 | 6.83e-01 | 82.1% | 91.6% |
| 5062478 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.91 | 74.0 | 7.23e-01 | 85.7% | 87.8% |
| 3410814 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.90 | 75.0 | 6.41e-01 | 86.9% | 64.8% |
| 4928205 | 150.1.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Ferritin | 0.90 | 76.0 | 5.94e-01 | 88.1% | 93.1% |
| 4940427 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.90 | 69.0 | 7.28e-01 | 79.8% | 97.3% |
| 4965788 | 150.1.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Ferritin | 0.90 | 70.0 | 5.75e-01 | 81.0% | 100.0% |
| 3497434 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.90 | 84.0 | 6.44e-01 | 100.0% | 54.9% |
| 3413600 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.90 | 76.0 | 6.43e-01 | 89.3% | 63.8% |
| 5002688 | 109.4.1.186 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ANAPC3 | 0.90 | 72.0 | 5.03e-01 | 84.5% | 32.5% |
| 4966860 | 150.1.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Ferritin | 0.89 | 69.0 | 5.81e-01 | 81.0% | 100.0% |
| 3257419 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.89 | 75.0 | 6.59e-01 | 92.9% | 63.3% |
| 3491432 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.88 | 82.0 | 6.42e-01 | 100.0% | 59.4% |
| 5022166 | 109.4.1.922 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_9 | 0.87 | 72.0 | 4.86e-01 | 86.9% | 30.5% |
| 3214864 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.87 | 76.0 | 6.13e-01 | 92.9% | 61.3% |
| 55698 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.86 | 77.0 | 6.03e-01 | 96.4% | 86.4% |
| 3239865 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.86 | 68.0 | 5.73e-01 | 83.3% | 68.9% |
| 3943946 | 150.1.1.7 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › DUF892 | 0.86 | 80.0 | 6.27e-01 | 100.0% | 95.8% |
| 4386662 | 3291.1.1.158 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Seryl_tRNA_N | 0.86 | 63.0 | 5.61e-01 | 76.2% | 55.7% |
| 3480252 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.86 | 66.0 | 6.98e-01 | 81.0% | 100.0% |
| 3709989 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.86 | 70.0 | 4.88e-01 | 86.9% | 29.2% |
| 3399734 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.85 | 76.0 | 6.30e-01 | 95.2% | 65.0% |
| 3477262 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.85 | 78.0 | 6.05e-01 | 100.0% | 83.4% |
| 3473214 | 150.1.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Ferritin | 0.85 | 76.0 | 5.83e-01 | 96.4% | 84.4% |
| 3737747 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.85 | 62.0 | 4.12e-01 | 77.4% | 21.4% |
| 3458391 | 109.4.1.235 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SRP68 | 0.85 | 78.0 | 5.31e-01 | 100.0% | 32.9% |
| 3287390 | 150.1.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Ferritin | 0.84 | 76.0 | 5.78e-01 | 96.4% | 80.6% |
| 3592972 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.84 | 73.0 | 5.42e-01 | 91.7% | 81.5% |
| 3786016 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.84 | 61.0 | 3.96e-01 | 76.2% | 18.8% |
| 1948686 | 150.1.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Ferritin | 0.83 | 78.0 | 5.87e-01 | 100.0% | 84.9% |
| 4007316 | 3291.1.1.4 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30 | 0.83 | 76.0 | 6.06e-01 | 97.6% | 100.0% |
| 4809272 | 3291.1.1.4 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30 | 0.83 | 60.0 | 5.23e-01 | 75.0% | 75.2% |
| 4099036 | 109.4.1.8 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1,TPR_12 | 0.82 | 60.0 | 4.64e-01 | 76.2% | 37.6% |
| 4881792 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.82 | 69.0 | 5.69e-01 | 90.5% | 57.2% |
| 3456188 | 109.7.1.10 ↗ | alpha superhelices › Repetitive alpha hairpins › Cytochrome c oxidase subunit E › Cytochrome c oxidase subunit E › WAV3_C | 0.82 | 67.0 | 7.02e-01 | 90.5% | 96.0% |
| 4947815 | 6155.1.1.0 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter | 0.82 | 58.0 | 5.48e-01 | 73.8% | 94.0% |
| 4024450 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.81 | 74.0 | 5.72e-01 | 100.0% | 52.8% |
| 4996707 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.81 | 66.0 | 6.78e-01 | 86.9% | 100.0% |
| 3968183 | 3758.2.1.1 ↗ | alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB | 0.81 | 75.0 | 5.95e-01 | 100.0% | 91.8% |
| 4274219 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.81 | 59.0 | 5.16e-01 | 78.6% | 53.3% |
| 3682397 | 604.12.1.65 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT_ATG1 | 0.80 | 66.0 | 6.26e-01 | 89.3% | 83.7% |
| 4881794 | 109.3.1.211 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › ANAPC5 | 0.80 | 59.0 | 4.87e-01 | 78.6% | 44.6% |
| 3736709 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.79 | 71.0 | 5.20e-01 | 100.0% | 59.1% |
| 3939940 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.78 | 70.0 | 5.92e-01 | 100.0% | 65.7% |
| 3414501 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.78 | 68.0 | 5.61e-01 | 95.2% | 63.4% |
| 3390738 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.78 | 61.0 | 4.26e-01 | 83.3% | 88.6% |
| 3275656 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.77 | 69.0 | 5.62e-01 | 97.6% | 62.0% |
| 3309583 | 604.12.1.65 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT_ATG1 | 0.77 | 58.0 | 5.92e-01 | 79.8% | 100.0% |
| 4947470 | 150.1.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Ferritin | 0.77 | 57.0 | 4.90e-01 | 79.8% | 96.3% |
| 5002499 | 3758.2.1.1 ↗ | alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB | 0.76 | 68.0 | 5.10e-01 | 98.8% | 91.2% |
| 5024278 | 3758.2.1.1 ↗ | alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB | 0.75 | 67.0 | 5.22e-01 | 98.8% | 96.7% |
| 3708191 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.74 | 61.0 | 6.36e-01 | 89.3% | 100.0% |
| 4027411 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.74 | 62.0 | 4.54e-01 | 89.3% | 44.2% |
| 4600200 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.74 | 54.0 | 4.89e-01 | 78.6% | 56.5% |
| 5047724 | 109.4.1.198 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12 | 0.74 | 66.0 | 4.14e-01 | 100.0% | 70.0% |
| 3580491 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.73 | 64.0 | 5.25e-01 | 100.0% | 58.7% |
| 3995816 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.72 | 53.0 | 5.38e-01 | 81.0% | 83.5% |
| 3266547 | 109.4.1.1307 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps52_CC, Vps52_C | 0.71 | 63.0 | 3.77e-01 | 97.6% | 24.5% |
| 5033233 | 3861.1.1.3 ↗ | alpha bundles › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › PF30661 | 0.71 | 63.0 | 4.43e-01 | 100.0% | 84.1% |
| 3608069 | 109.24.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical domain in dedicator of cytokinesis protein 9 › Helical domain in dedicator of cytokinesis protein 9 | 0.70 | 58.0 | 5.19e-01 | 91.7% | 79.7% |
| 3751245 | 633.23.1.8 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › DUF4534 | 0.69 | 61.0 | 5.05e-01 | 98.8% | 66.7% |
| 4370734 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.67 | 53.0 | 4.02e-01 | 86.9% | 42.4% |
D2
high
residues 589-685
Domain cluster:
representative
CATH (45)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3tulB00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.92 | 64.0 | 5.67e-01 | 76.3% | 52.6% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.90 | 66.0 | 5.56e-01 | 75.3% | 97.3% |
| 2ib0A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.89 | 67.0 | 5.89e-01 | 78.4% | 100.0% |
| 1wvtA00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.88 | 64.0 | 5.45e-01 | 75.3% | 92.6% |
| 2vxxA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.88 | 63.0 | 5.04e-01 | 73.2% | 83.7% |
| 1tjoB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.87 | 62.0 | 4.96e-01 | 73.2% | 82.3% |
| 5fzsA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.85 | 50.0 | 4.88e-01 | 75.3% | 54.2% |
| 4gyoA02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.85 | 53.0 | 3.93e-01 | 72.2% | 27.7% |
| 1lkoA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.84 | 59.0 | 5.04e-01 | 72.2% | 91.0% |
| 1nfvA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.83 | 61.0 | 4.96e-01 | 76.3% | 80.5% |
| 2katA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.82 | 51.0 | 4.84e-01 | 71.1% | 53.0% |
| 3fseB02 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.82 | 60.0 | 5.24e-01 | 76.3% | 97.2% |
| 4i1aA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.82 | 53.0 | 3.76e-01 | 70.1% | 23.4% |
| 6xssA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.82 | 46.0 | 5.41e-01 | 72.2% | 78.3% |
| 1lf6A02 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.82 | 57.0 | 3.66e-01 | 71.1% | 20.4% |
| 3w7tA03 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.81 | 58.0 | 3.66e-01 | 74.2% | 34.1% |
| 1ya0A01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.80 | 58.0 | 4.45e-01 | 80.4% | 35.4% |
| 7e9uA01 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.79 | 57.0 | 3.60e-01 | 74.2% | 32.7% |
| 4gywA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.79 | 44.0 | 4.33e-01 | 72.2% | 51.4% |
| 3lmfA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.79 | 58.0 | 5.55e-01 | 76.3% | 73.4% |
| 3zsuA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.78 | 60.0 | 5.59e-01 | 80.4% | 74.6% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.78 | 55.0 | 5.51e-01 | 80.4% | 71.0% |
| 1tqgA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.78 | 60.0 | 5.90e-01 | 81.4% | 76.2% |
| 2v6yA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.78 | 56.0 | 6.26e-01 | 75.3% | 98.7% |
| 3pwxA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.78 | 70.0 | 5.66e-01 | 100.0% | 62.5% |
| 6jpaE00 | 1.20.140.150 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.78 | 59.0 | 4.82e-01 | 79.4% | 64.5% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.77 | 68.0 | 6.34e-01 | 94.8% | 96.6% |
| 2i0mA02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.76 | 59.0 | 5.83e-01 | 80.4% | 93.1% |
| 2crbA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.76 | 53.0 | 5.39e-01 | 72.2% | 77.3% |
| 1vctA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.76 | 56.0 | 5.39e-01 | 77.3% | 88.1% |
| 3f4mA00 | 1.20.1440.160 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like | 0.74 | 55.0 | 4.65e-01 | 77.3% | 53.9% |
| 3kezA01 | 1.25.40.390 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.73 | 56.0 | 4.11e-01 | 79.4% | 38.3% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 50.0 | 4.82e-01 | 70.1% | 100.0% |
| 6adqG01 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.73 | 57.0 | 4.69e-01 | 84.5% | 61.2% |
| 2lqgA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.72 | 56.0 | 5.01e-01 | 83.5% | 74.6% |
| 1kz7A01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.72 | 51.0 | 4.05e-01 | 74.2% | 37.8% |
| 6w08A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.71 | 62.0 | 4.22e-01 | 95.9% | 75.7% |
| 2fupA00 | 1.20.58.300 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like | 0.71 | 52.0 | 4.69e-01 | 76.3% | 91.3% |
| 7powA01 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.70 | 49.0 | 3.84e-01 | 72.2% | 61.1% |
| 1orjD00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.69 | 53.0 | 4.86e-01 | 80.4% | 71.2% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 62.0 | 5.15e-01 | 100.0% | 88.4% |
| 2l3lA01 | 1.20.58.1250 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain | 0.67 | 57.0 | 5.61e-01 | 92.8% | 87.7% |
| 3ggyA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.65 | 54.0 | 4.41e-01 | 91.8% | 100.0% |
| 2vtyA00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.59 | 44.0 | 3.86e-01 | 77.3% | 83.3% |
| 3l1nA02 | 1.20.1280.140 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.58 | 40.0 | 4.22e-01 | 72.2% | 97.7% |
ECOD (45)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3405706 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.90 | 70.0 | 6.24e-01 | 80.4% | 66.2% |
| 5062478 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.90 | 70.0 | 7.28e-01 | 80.4% | 94.4% |
| 3411310 | 633.23.1.4 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › Claudin_2 | 0.89 | 79.0 | 5.82e-01 | 93.8% | 54.7% |
| 5064482 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.88 | 66.0 | 5.43e-01 | 78.4% | 71.5% |
| 3385614 | 7516.1.1.2 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 | 0.88 | 60.0 | 4.12e-01 | 70.1% | 23.4% |
| 5045256 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.88 | 67.0 | 6.82e-01 | 79.4% | 97.9% |
| 3257419 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.87 | 60.0 | 5.54e-01 | 72.2% | 57.5% |
| 3936715 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.86 | 71.0 | 6.24e-01 | 86.6% | 70.3% |
| 3413600 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.86 | 67.0 | 5.97e-01 | 80.4% | 65.4% |
| 3408518 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.86 | 66.0 | 6.00e-01 | 80.4% | 66.4% |
| 5076762 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.85 | 60.0 | 5.34e-01 | 74.2% | 53.8% |
| 3399734 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.84 | 67.0 | 5.84e-01 | 83.5% | 67.1% |
| 3691273 | 109.3.1.242 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Fungal_trans_2 | 0.84 | 60.0 | 5.06e-01 | 76.3% | 46.5% |
| 5022166 | 109.4.1.922 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_9 | 0.84 | 59.0 | 4.10e-01 | 72.2% | 28.4% |
| 3491432 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.83 | 68.0 | 5.62e-01 | 86.6% | 60.6% |
| 3637210 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.83 | 58.0 | 3.94e-01 | 74.2% | 21.9% |
| 3843153 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.83 | 68.0 | 5.99e-01 | 86.6% | 70.4% |
| 3923558 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.82 | 62.0 | 4.92e-01 | 78.4% | 46.5% |
| 4955870 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.82 | 66.0 | 5.29e-01 | 84.5% | 62.2% |
| 4881794 | 109.3.1.211 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › ANAPC5 | 0.82 | 54.0 | 4.68e-01 | 70.1% | 44.6% |
| 3831265 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.81 | 58.0 | 5.90e-01 | 74.2% | 76.8% |
| 3603360 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.81 | 61.0 | 5.70e-01 | 78.4% | 88.7% |
| 3214864 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.81 | 65.0 | 5.61e-01 | 86.6% | 65.3% |
| 3498899 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.80 | 64.0 | 5.65e-01 | 83.5% | 64.4% |
| 3524525 | 633.23.1.4 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › Claudin_2 | 0.80 | 66.0 | 4.97e-01 | 87.6% | 55.5% |
| 3597864 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.79 | 60.0 | 5.47e-01 | 79.4% | 80.0% |
| 3847975 | 604.12.1.9 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › ATG1-like_MIT2 | 0.79 | 55.0 | 5.55e-01 | 71.1% | 76.8% |
| 4999686 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.79 | 54.0 | 6.02e-01 | 71.1% | 98.7% |
| 5048301 | 109.4.1.195 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_11 | 0.79 | 45.0 | 3.49e-01 | 71.1% | 27.8% |
| 165995 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.78 | 56.0 | 6.26e-01 | 75.3% | 98.7% |
| 5033233 | 3861.1.1.3 ↗ | alpha bundles › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › PF30661 | 0.78 | 59.0 | 4.20e-01 | 79.4% | 34.1% |
| 5044407 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.77 | 70.0 | 5.82e-01 | 96.9% | 71.2% |
| 3398428 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.77 | 60.0 | 5.18e-01 | 83.5% | 70.0% |
| 3245848 | 109.4.1.3118 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, TPR_8, TPR_16 | 0.76 | 57.0 | 3.37e-01 | 78.4% | 12.3% |
| 3608673 | 109.4.1.194 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_10 | 0.76 | 55.0 | 3.71e-01 | 75.3% | 45.8% |
| 4987735 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.76 | 55.0 | 5.22e-01 | 75.3% | 73.0% |
| 3837868 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.76 | 59.0 | 3.86e-01 | 82.5% | 38.0% |
| 3724953 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.76 | 59.0 | 5.06e-01 | 83.5% | 70.3% |
| 4370734 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.76 | 56.0 | 4.28e-01 | 76.3% | 42.4% |
| 1719259 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.76 | 56.0 | 4.34e-01 | 77.3% | 38.6% |
| 3964581 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.75 | 56.0 | 4.29e-01 | 77.3% | 43.3% |
| 3374962 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.71 | 57.0 | 5.35e-01 | 86.6% | 98.3% |
| 3578688 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.65 | 47.0 | 3.48e-01 | 76.3% | 29.2% |
| 3386740 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.61 | 51.0 | 3.88e-01 | 91.8% | 97.0% |
| 3486274 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 46.0 | 3.82e-01 | 95.9% | 91.4% |
D3
high
residues 707-779
Domain cluster:
representative
CATH (37)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3d7iB00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.80 | 56.0 | 5.03e-01 | 82.2% | 54.1% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.78 | 58.0 | 4.58e-01 | 78.1% | 66.4% |
| 1h6gA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.75 | 55.0 | 4.60e-01 | 76.7% | 70.6% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.72 | 57.0 | 4.87e-01 | 84.9% | 88.8% |
| 3fbzA01 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 62.0 | 5.59e-01 | 100.0% | 82.4% |
| 4hehA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.70 | 48.0 | 4.65e-01 | 75.3% | 63.9% |
| 1x3kA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.69 | 59.0 | 4.84e-01 | 100.0% | 65.3% |
| 6ll8A01 | 3.90.1640.10 | Alpha Beta › Alpha-Beta Complex › inorganic pyrophosphatase (n-terminal core) › inorganic pyrophosphatase (n-terminal core) | 0.69 | 60.0 | 4.55e-01 | 100.0% | 94.1% |
| 3rvyA01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.68 | 46.0 | 4.04e-01 | 71.2% | 80.7% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.67 | 48.0 | 4.13e-01 | 75.3% | 90.6% |
| 4iluA02 | 1.20.58.1290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain | 0.67 | 55.0 | 4.76e-01 | 89.0% | 81.1% |
| 3lssA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.67 | 46.0 | 4.03e-01 | 71.2% | 90.2% |
| 7zmgL01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.67 | 48.0 | 4.71e-01 | 76.7% | 83.7% |
| 3if8B02 | 1.20.58.730 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 39.0 | 3.53e-01 | 91.8% | 44.0% |
| 1x46A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.65 | 56.0 | 4.54e-01 | 100.0% | 68.0% |
| 1zp2A01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.65 | 52.0 | 4.55e-01 | 100.0% | 57.4% |
| 6r1nA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.64 | 43.0 | 3.92e-01 | 71.2% | 94.2% |
| 2hjmA01 | 1.20.120.460 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › protein pf1176 like | 0.63 | 46.0 | 4.36e-01 | 76.7% | 74.4% |
| 3zdrA02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.63 | 49.0 | 3.54e-01 | 84.9% | 67.1% |
| 7wu8B01 | 1.20.1160.20 | Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › | 0.62 | 47.0 | 4.66e-01 | 82.2% | 75.9% |
| 3qo8A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.62 | 37.0 | 3.35e-01 | 74.0% | 40.6% |
| 2kw6A00 | 6.10.140.1300 | Special › Helix non-globular › Helix Hairpins › | 0.61 | 43.0 | 4.55e-01 | 76.7% | 83.1% |
| 3nbxX03 | 1.20.58.1510 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 44.0 | 4.04e-01 | 78.1% | 85.1% |
| 2gscC00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.60 | 49.0 | 4.34e-01 | 91.8% | 92.7% |
| 2aw6A02 | 1.25.40.400 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.60 | 48.0 | 3.50e-01 | 90.4% | 43.4% |
| 2gz6A00 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.60 | 53.0 | 3.33e-01 | 97.3% | 37.9% |
| 2lseA00 | 1.20.120.1360 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.59 | 52.0 | 4.64e-01 | 98.6% | 69.3% |
| 3gt5A00 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.57 | 51.0 | 3.20e-01 | 100.0% | 94.9% |
| 2w0gA00 | 1.20.58.610 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Cdc37, Hsp90 binding domain | 0.56 | 41.0 | 3.52e-01 | 84.9% | 45.7% |
| 1iurA01 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.56 | 39.0 | 4.15e-01 | 75.3% | 98.4% |
| 4v1sA00 | 1.50.10.20 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.56 | 48.0 | 3.10e-01 | 98.6% | 66.3% |
| 2elcA01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.55 | 38.0 | 3.91e-01 | 78.1% | 77.6% |
| 3d1bB00 | 1.20.920.40 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › | 0.55 | 49.0 | 4.33e-01 | 100.0% | 98.1% |
| 1m4rB00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.55 | 46.0 | 3.85e-01 | 100.0% | 66.0% |
| 1fntc01 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.54 | 40.0 | 3.00e-01 | 79.5% | 58.0% |
| 6tqpA01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.51 | 40.0 | 3.33e-01 | 90.4% | 47.1% |
| 5mmiJ02 | 1.10.10.250 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Ribosomal protein L11/L12, C-terminal domain | 0.51 | 35.0 | 3.58e-01 | 72.6% | 94.2% |
ECOD (35)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3581554 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.78 | 58.0 | 3.97e-01 | 76.7% | 77.8% |
| 5038395 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.77 | 57.0 | 4.40e-01 | 78.1% | 61.9% |
| 2878134 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.77 | 54.0 | 4.28e-01 | 72.6% | 60.0% |
| 3801633 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.76 | 54.0 | 4.16e-01 | 74.0% | 81.9% |
| 3686122 | 633.23.1.9 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › SUR7 | 0.76 | 56.0 | 3.88e-01 | 78.1% | 93.6% |
| 3973500 | 601.1.2.144 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › HBM | 0.72 | 59.0 | 5.04e-01 | 87.7% | 92.2% |
| 3878696 | 2004.1.1.149 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SecA_DEAD | 0.72 | 56.0 | 3.31e-01 | 100.0% | 10.4% |
| 4019922 | 611.4.1.0 ↗ | alpha bundles › N-cbl like › PG0775 C-terminal domain-like › PG0775 C-terminal domain-like | 0.72 | 50.0 | 3.71e-01 | 71.2% | 59.4% |
| 3993045 | 109.4.1.202 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_16 | 0.71 | 51.0 | 4.13e-01 | 75.3% | 72.6% |
| 4998334 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.70 | 55.0 | 5.19e-01 | 86.3% | 84.4% |
| 4937489 | 180.1.1.1 ↗ | alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › PAP2 | 0.70 | 61.0 | 4.92e-01 | 100.0% | 63.5% |
| 3184827 | 3691.1.1.1 ↗ | alpha arrays › Phosphomannose isomerase helical insertion domain › Phosphomannose isomerase helical insertion domain › Phosphomannose isomerase helical insertion domain › PMI_typeI_hel | 0.70 | 53.0 | 4.47e-01 | 80.8% | 96.7% |
| 3773184 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.70 | 51.0 | 4.04e-01 | 76.7% | 50.3% |
| 3384541 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.68 | 53.0 | 4.13e-01 | 83.6% | 64.5% |
| 1392345 | 4995.1.1.2 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › AppA_4HB | 0.68 | 51.0 | 4.67e-01 | 82.2% | 60.0% |
| 3788353 | 109.4.1.681 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans_2 | 0.68 | 59.0 | 3.65e-01 | 98.6% | 88.7% |
| 3163811 | 2004.1.1.430 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran, ABC_tran_Xtn | 0.66 | 58.0 | 3.48e-01 | 98.6% | 13.2% |
| 3944203 | 4275.1.1.7 ↗ | alpha arrays › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like › Phage_GPL | 0.66 | 47.0 | 3.98e-01 | 76.7% | 78.5% |
| 4951126 | 1.1.5.17 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › DUF447_N | 0.65 | 55.0 | 4.13e-01 | 94.5% | 95.6% |
| 3488467 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.64 | 54.0 | 4.81e-01 | 100.0% | 68.7% |
| 3257076 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.63 | 50.0 | 4.02e-01 | 86.3% | 46.2% |
| 5008560 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.63 | 45.0 | 4.01e-01 | 80.8% | 51.4% |
| 4529712 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.63 | 50.0 | 4.51e-01 | 86.3% | 80.0% |
| 5054469 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.63 | 46.0 | 4.12e-01 | 78.1% | 91.4% |
| 4994292 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.62 | 48.0 | 4.39e-01 | 80.8% | 79.8% |
| 3574560 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.60 | 51.0 | 4.76e-01 | 100.0% | 76.7% |
| 3694032 | 551.1.1.0 ↗ | alpha arrays › Hsp90 co-chaperone CDC37 middle domain › Hsp90 co-chaperone CDC37 middle domain › Hsp90 co-chaperone CDC37 middle domain | 0.60 | 45.0 | 3.93e-01 | 97.3% | 52.2% |
| 3530124 | 386.1.1.0 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers | 0.59 | 42.0 | 4.10e-01 | 78.1% | 68.8% |
| 3321841 | 109.4.1.350 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ELYS | 0.56 | 48.0 | 3.17e-01 | 100.0% | 29.1% |
| 5012706 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.56 | 48.0 | 4.18e-01 | 98.6% | 76.5% |
| 3795940 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 45.0 | 2.90e-01 | 89.0% | 24.6% |
| 4934424 | 2004.1.1.76 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF87 | 0.55 | 46.0 | 3.05e-01 | 100.0% | 21.9% |
| 3202400 | 622.1.1.20 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › Het-C | 0.55 | 44.0 | 3.43e-01 | 91.8% | 58.9% |
| 3505626 | 186.2.1.1 ↗ | alpha arrays › lambda integrase-N-like › VEFS domain › VEFS domain › VEFS-Box | 0.54 | 41.0 | 3.84e-01 | 84.9% | 81.1% |
| 3271624 | 2004.1.1.184 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 | 0.52 | 43.0 | 2.75e-01 | 100.0% | 22.5% |
D4
high
residues 828-900
Domain cluster:
representative
CATH (23)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2ooeA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.79 | 58.0 | 4.19e-01 | 76.7% | 36.8% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.71 | 52.0 | 4.44e-01 | 76.7% | 93.2% |
| 4abnA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.71 | 50.0 | 3.37e-01 | 74.0% | 34.8% |
| 2bvlA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 50.0 | 4.75e-01 | 76.7% | 94.2% |
| 1m62A00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.69 | 50.0 | 4.72e-01 | 76.7% | 90.8% |
| 2guzB00 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.68 | 50.0 | 5.24e-01 | 76.7% | 100.0% |
| 6a6fA00 | 3.90.1010.10 | Alpha Beta › Alpha-Beta Complex › Sufe protein. Chain: A › | 0.68 | 50.0 | 4.12e-01 | 79.5% | 55.1% |
| 4dmvA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 48.0 | 4.63e-01 | 76.7% | 94.1% |
| 2dkwA00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.65 | 45.0 | 3.77e-01 | 72.6% | 62.6% |
| 5ffdA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.65 | 47.0 | 3.81e-01 | 76.7% | 63.5% |
| 3frqB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.62 | 55.0 | 4.14e-01 | 100.0% | 56.5% |
| 4epzA00 | 1.25.40.810 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › UpxZ | 0.62 | 47.0 | 3.68e-01 | 80.8% | 44.8% |
| 1b5lA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.60 | 50.0 | 4.04e-01 | 95.9% | 69.1% |
| 3c8zA02 | 1.20.120.640 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0.59 | 44.0 | 4.22e-01 | 78.1% | 73.5% |
| 1d1dA02 | 1.10.1200.30 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Retrovirus capsid C-terminal domain | 0.58 | 43.0 | 4.21e-01 | 80.8% | 91.3% |
| 5hdiA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.58 | 50.0 | 3.21e-01 | 100.0% | 70.8% |
| 2db0B00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.58 | 46.0 | 3.29e-01 | 90.4% | 40.8% |
| 1blwC00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.58 | 49.0 | 3.92e-01 | 93.2% | 70.2% |
| 2wzkA02 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.57 | 45.0 | 3.83e-01 | 87.7% | 87.4% |
| 3fbzA01 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 42.0 | 3.85e-01 | 82.2% | 61.8% |
| 1noyB02 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.56 | 42.0 | 2.95e-01 | 79.5% | 74.3% |
| 4v19W00 | 3.90.470.10 | Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › Ribosomal protein L22/L17 | 0.54 | 42.0 | 3.33e-01 | 87.7% | 82.5% |
| 2k9sA00 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.51 | 40.0 | 3.50e-01 | 83.6% | 72.9% |
ECOD (39)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3269637 | 603.1.1.105 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF31021 | 0.79 | 55.0 | 4.64e-01 | 71.2% | 79.1% |
| 3257141 | 141.1.1.2 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › SQS_PSY | 0.77 | 56.0 | 3.46e-01 | 76.7% | 23.2% |
| 3801203 | 109.4.1.2247 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2, TPR_6, TPR_8, TPR_19 | 0.76 | 54.0 | 3.07e-01 | 74.0% | 14.6% |
| 3224980 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.75 | 51.0 | 4.89e-01 | 71.2% | 96.5% |
| 3358888 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.74 | 53.0 | 4.60e-01 | 75.3% | 64.5% |
| 3576628 | 109.21.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nup96 | 0.74 | 58.0 | 3.42e-01 | 84.9% | 43.6% |
| 3386216 | 2008.1.1.101 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_4 | 0.73 | 52.0 | 3.63e-01 | 74.0% | 82.7% |
| 3435257 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.73 | 51.0 | 4.24e-01 | 72.6% | 51.2% |
| 4396768 | 206.1.1.66 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › CLU | 0.72 | 56.0 | 3.83e-01 | 83.6% | 83.2% |
| 4982833 | 2004.1.1.76 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF87 | 0.71 | 55.0 | 3.42e-01 | 80.8% | 18.6% |
| 3621553 | 109.4.1.362 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1,TPR_8 | 0.70 | 49.0 | 3.22e-01 | 72.6% | 18.7% |
| 4012164 | 1134.1.1.0 ↗ | alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain | 0.70 | 50.0 | 5.28e-01 | 75.3% | 92.3% |
| 3579322 | 109.4.1.210 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_19 | 0.70 | 50.0 | 3.21e-01 | 74.0% | 27.8% |
| 60095 | 109.6.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ras GEF › Ras GEF | 0.70 | 62.0 | 4.88e-01 | 100.0% | 54.1% |
| 3893140 | 109.6.1.4 ↗ | alpha superhelices › Repetitive alpha hairpins › Ras GEF › Ras GEF › RanGAP1_C | 0.70 | 61.0 | 4.82e-01 | 98.6% | 57.4% |
| 4003695 | 109.4.1.2564 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_8, TPR_10, TPR_19 | 0.70 | 49.0 | 2.86e-01 | 74.0% | 13.9% |
| 3577145 | 4030.1.1.0 ↗ | alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz | 0.70 | 49.0 | 5.44e-01 | 74.0% | 98.2% |
| 3742155 | 109.21.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nup96 | 0.68 | 53.0 | 3.12e-01 | 84.9% | 17.1% |
| 3413267 | 101.1.1.66 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_5 | 0.67 | 51.0 | 4.97e-01 | 80.8% | 85.0% |
| 3413946 | 101.1.1.66 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_5 | 0.67 | 50.0 | 5.17e-01 | 79.5% | 92.9% |
| 3938667 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.66 | 53.0 | 4.95e-01 | 86.3% | 91.1% |
| 4567912 | 109.4.1.109 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sel1 | 0.66 | 49.0 | 3.64e-01 | 80.8% | 31.4% |
| 3838593 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.65 | 46.0 | 3.89e-01 | 75.3% | 80.0% |
| 3246380 | 4207.1.2.0 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region | 0.64 | 49.0 | 4.07e-01 | 82.2% | 58.5% |
| 3858558 | 4207.1.2.5 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region › TEX13 | 0.64 | 45.0 | 4.47e-01 | 75.3% | 72.0% |
| 5071262 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.64 | 46.0 | 2.92e-01 | 76.7% | 17.4% |
| 3741033 | 109.4.1.1393 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF26715 | 0.64 | 49.0 | 3.71e-01 | 84.9% | 71.9% |
| 3650518 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 52.0 | 3.58e-01 | 93.2% | 52.0% |
| 5061191 | 186.1.1.0 ↗ | alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N | 0.62 | 46.0 | 4.30e-01 | 82.2% | 70.5% |
| 5050809 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 52.0 | 3.35e-01 | 97.3% | 63.2% |
| 3968976 | 616.1.1.0 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain | 0.61 | 51.0 | 4.81e-01 | 100.0% | 90.5% |
| 3896763 | 101.1.1.66 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_5 | 0.61 | 46.0 | 4.41e-01 | 82.2% | 82.4% |
| 137614 | 206.1.3.3 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › PPDK_N | 0.60 | 53.0 | 3.35e-01 | 100.0% | 25.8% |
| 3598953 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.59 | 48.0 | 3.06e-01 | 91.8% | 26.3% |
| 4657257 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.58 | 47.0 | 2.54e-01 | 86.3% | 40.9% |
| 3631079 | 101.1.1.335 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › PF25871 | 0.58 | 43.0 | 3.98e-01 | 80.8% | 100.0% |
| 4997950 | 213.1.1.17 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › DUF1122 | 0.56 | 43.0 | 3.20e-01 | 86.3% | 48.8% |
| 4964803 | 2004.1.1.1220 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PF26510 | 0.51 | 43.0 | 3.04e-01 | 97.3% | 58.0% |
| 3291169 | 101.1.1.2 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HTH_AraC | 0.50 | 34.0 | 3.73e-01 | 71.2% | 100.0% |
D5
medium
residues 1-72
Domain cluster:
representative
CATH (13)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2ddmB00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.74 | 58.0 | 3.87e-01 | 83.3% | 92.3% |
| 2e6oA00 | 1.10.30.10 | Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain | 0.66 | 48.0 | 4.53e-01 | 76.4% | 69.0% |
| 3g2bA00 | 1.10.10.1150 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Coenzyme PQQ synthesis protein D (PqqD) | 0.65 | 41.0 | 3.80e-01 | 84.7% | 50.0% |
| 2abqA00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.64 | 49.0 | 3.23e-01 | 81.9% | 93.1% |
| 3ibyD02 | 1.10.287.1770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 50.0 | 4.77e-01 | 84.7% | 84.5% |
| 2nq2A00 | 1.10.3470.10 | Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC | 0.59 | 46.0 | 3.09e-01 | 87.5% | 71.4% |
| 4jkzA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.58 | 44.0 | 3.20e-01 | 79.2% | 50.8% |
| 3l6gA01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.56 | 47.0 | 3.76e-01 | 94.4% | 90.7% |
| 2kjgA00 | 1.20.120.970 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.55 | 43.0 | 3.90e-01 | 87.5% | 62.6% |
| 1qduB00 | 3.30.70.1470 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Caspase-like | 0.54 | 42.0 | 4.02e-01 | 87.5% | 79.5% |
| 2juaA00 | 1.20.1480.30 | Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › Designed four-helix bundle protein | 0.53 | 42.0 | 3.79e-01 | 88.9% | 91.2% |
| 3zevB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 42.0 | 2.91e-01 | 100.0% | 73.4% |
| 3kp1E02 | 1.10.8.1000 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ornithine 4,5 aminomutase S component, alpha subunit-like | 0.51 | 34.0 | 3.52e-01 | 80.6% | 74.3% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3384012 | 108.1.1.99 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_5, EF-hand_6, EF-hand_7 | 0.78 | 47.0 | 3.74e-01 | 88.9% | 33.3% |
| 3925672 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.65 | 44.0 | 4.31e-01 | 70.8% | 62.5% |
| 3333775 | 103.15.1.0 ↗ | alpha arrays › RuvA-C › Mitoribosomal protein mS23 › Mitoribosomal protein mS23 | 0.65 | 48.0 | 3.95e-01 | 77.8% | 55.2% |
| 3588797 | 4084.1.1.0 ↗ | alpha bundles › ChaB-like › ChaB-like › ChaB-like | 0.63 | 49.0 | 5.18e-01 | 83.3% | 95.4% |
| 4679946 | 3869.1.1.1 ↗ | alpha arrays › Mitochondrial 54S ribosomal protein L2 › Mitochondrial 54S ribosomal protein L2 › Mitochondrial 54S ribosomal protein L2 › Ribosomal_L27_C | 0.63 | 57.0 | 4.05e-01 | 100.0% | 36.4% |
| 4995050 | 5051.1.1.3 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › SSF | 0.61 | 55.0 | 3.33e-01 | 100.0% | 69.1% |
| 4162384 | 633.23.1.37 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › PF29133 | 0.59 | 51.0 | 3.63e-01 | 98.6% | 39.6% |
| 5076097 | 1076.1.1.0 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related | 0.59 | 52.0 | 4.00e-01 | 100.0% | 98.2% |
| 4065157 | 2005.1.1.25 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › HIGH_NTase1 | 0.56 | 45.0 | 2.80e-01 | 87.5% | 26.0% |
| 3604256 | 3558.1.1.0 ↗ | alpha arrays › HSDR subunit helical domain › HSDR subunit helical domain › HSDR subunit helical domain | 0.53 | 38.0 | 3.39e-01 | 80.6% | 64.3% |
D6
medium
residues 172-263
Domain cluster:
representative
ECOD (2)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5043887 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.86 | 68.0 | 6.13e-01 | 83.7% | 63.3% |
| 5071097 | 3834.1.1.25 ↗ | alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain › DUF7121 | 0.82 | 66.0 | 4.53e-01 | 88.0% | 27.4% |
D7
medium
residues 913-932_995-1112
Domain cluster:
rep: KR063281.1__AKJ72552.1__GMA2_14__00014__D100-243
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03496.21 best | ADPrib_exo_Tox | 34.8 | 1.50e-08 | 64.5% | 41.5% |
CATH (23)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4xsgB00 | 3.90.176.10 | Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 | 0.89 | 74.0 | 6.32e-01 | 86.2% | 100.0% |
| 4fk7A00 | 3.90.176.10 | Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 | 0.88 | 73.0 | 6.29e-01 | 86.2% | 100.0% |
| 1ojqA00 | 3.90.176.10 | Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 | 0.88 | 75.0 | 6.32e-01 | 88.4% | 100.0% |
| 1gzeA00 | 3.90.176.10 | Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 | 0.87 | 76.0 | 6.45e-01 | 89.9% | 99.0% |
| 1qs1A02 | 3.90.176.10 | Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 | 0.87 | 72.0 | 6.27e-01 | 86.2% | 100.0% |
| 1qs1A01 | 3.90.176.10 | Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 | 0.82 | 69.0 | 5.91e-01 | 87.0% | 100.0% |
| 4h03A02 | 3.90.176.10 | Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 | 0.80 | 71.0 | 6.10e-01 | 92.0% | 100.0% |
| 5wtzA01 | 3.90.176.10 | Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 | 0.80 | 68.0 | 5.74e-01 | 88.4% | 96.7% |
| 3u0jA00 | 3.90.176.10 | Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 | 0.79 | 61.0 | 5.01e-01 | 79.7% | 79.3% |
| 2j3vA02 | 3.90.176.10 | Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 | 0.78 | 71.0 | 6.03e-01 | 96.4% | 100.0% |
| 6k93A00 | 3.90.176.10 | Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 | 0.77 | 57.0 | 4.66e-01 | 79.7% | 43.9% |
| 2j3xA01 | 3.90.176.10 | Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 | 0.77 | 65.0 | 5.51e-01 | 89.1% | 98.2% |
| 2wn5A01 | 3.90.176.10 | Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 | 0.74 | 60.0 | 5.27e-01 | 84.8% | 99.0% |
| 1yqyA01 | 3.90.176.10 | Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 | 0.74 | 65.0 | 5.59e-01 | 92.0% | 100.0% |
| 4xzjA01 | 3.90.176.10 | Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 | 0.71 | 64.0 | 5.42e-01 | 94.2% | 95.7% |
| 1eu3A02 | 2.40.50.110 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.60 | 31.0 | 3.86e-01 | 86.2% | 82.5% |
| 2d3aA01 | 3.10.20.70 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Glutamine synthetase, N-terminal domain | 0.57 | 33.0 | 3.73e-01 | 92.8% | 75.2% |
| 1zpsA01 | 3.10.20.810 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphoribosyl-AMP cyclohydrolase | 0.52 | 28.0 | 3.33e-01 | 92.0% | 75.8% |
| 3q91B00 | 3.90.79.10 | Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase | 0.52 | 30.0 | 3.12e-01 | 91.3% | 59.5% |
| 4hpqB00 | 2.60.270.60 | Mainly Beta › Sandwich › Mutm (Fpg) Protein; Chain: A, domain 2 › Autophagy-related protein 31 | 0.52 | 29.0 | 3.14e-01 | 90.6% | 65.2% |
| 2k75A01 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.52 | 35.0 | 3.98e-01 | 73.2% | 93.2% |
| 7cayA01 | 2.30.130.40 | Mainly Beta › Roll › Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 › LON domain-like | 0.52 | 32.0 | 3.68e-01 | 84.8% | 85.0% |
| 7tuvA02 | 2.40.50.700 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.51 | 29.0 | 3.44e-01 | 88.4% | 83.9% |
ECOD (25)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7442 | 237.1.1.8 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox | 0.88 | 75.0 | 6.32e-01 | 88.4% | 100.0% |
| 7440 | 237.1.1.8 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox | 0.87 | 72.0 | 6.27e-01 | 86.2% | 100.0% |
| 157262 | 237.1.1.8 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox | 0.86 | 76.0 | 6.42e-01 | 90.6% | 99.0% |
| 4157545 | 237.1.1.8 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox | 0.82 | 61.0 | 5.88e-01 | 79.0% | 70.0% |
| 2034328 | 237.1.1.8 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox | 0.81 | 67.0 | 5.72e-01 | 86.2% | 96.7% |
| 4424922 | 237.1.1.34 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ART, ADPrib_exo_Tox | 0.80 | 61.0 | 5.08e-01 | 87.0% | 47.8% |
| 3280971 | 237.1.1.8 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox | 0.79 | 64.0 | 6.07e-01 | 84.1% | 98.7% |
| 3847347 | 237.1.1.2 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ART | 0.78 | 61.0 | 5.03e-01 | 87.0% | 48.3% |
| 308110 | 237.1.1.8 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox | 0.78 | 65.0 | 5.50e-01 | 87.0% | 98.1% |
| 2547952 | 237.1.1.34 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ART, ADPrib_exo_Tox | 0.77 | 57.0 | 4.66e-01 | 79.7% | 43.9% |
| 3714758 | 237.1.1.0 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation | 0.77 | 63.0 | 5.12e-01 | 86.2% | 58.4% |
| 3886084 | 237.1.1.2 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ART | 0.76 | 61.0 | 5.07e-01 | 86.2% | 51.1% |
| 3612144 | 237.1.1.0 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation | 0.76 | 62.0 | 4.50e-01 | 86.2% | 40.8% |
| 4947785 | 239.1.1.0 ↗ | beta barrels › Ribosomal protein L25-like › Ribosomal protein L25-like › Ribosomal protein L25-like | 0.75 | 32.0 | 4.51e-01 | 90.6% | 81.2% |
| 2410012 | 237.1.1.2 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ART | 0.75 | 59.0 | 5.30e-01 | 81.9% | 83.2% |
| 3534305 | 237.1.1.2 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ART | 0.74 | 54.0 | 4.53e-01 | 85.5% | 45.4% |
| 3561821 | 237.1.1.2 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ART | 0.74 | 62.0 | 5.02e-01 | 87.7% | 71.8% |
| 1687631 | 237.1.1.8 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox | 0.70 | 64.0 | 5.34e-01 | 96.4% | 95.5% |
| 4301058 | 237.1.1.39 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › DRAT | 0.62 | 48.0 | 4.01e-01 | 81.2% | 93.2% |
| 4245054 | 1.1.9.5 ↗ | beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg | 0.57 | 34.0 | 2.83e-01 | 83.3% | 33.8% |
| 4995609 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.54 | 39.0 | 3.89e-01 | 74.6% | 86.2% |
| 3506791 | 2.1.1.69 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › RMI2 | 0.54 | 38.0 | 3.80e-01 | 73.2% | 80.7% |
| 3426514 | 2.1.1.7 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › S1 | 0.53 | 38.0 | 4.32e-01 | 72.5% | 100.0% |
| 4481366 | 1.1.9.5 ↗ | beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg | 0.51 | 33.0 | 2.81e-01 | 84.1% | 39.1% |
| 3202747 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.50 | 31.0 | 3.62e-01 | 73.9% | 89.5% |
D8
medium
residues 933-994
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03496.21 best | ADPrib_exo_Tox | 24.0 | 3.10e-05 | 98.4% | 25.1% |
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1jlcB03 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.62 | 40.0 | 3.15e-01 | 80.6% | 30.8% |
| 3eabE00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.56 | 40.0 | 3.67e-01 | 100.0% | 55.8% |
| 1lujB01 | 1.10.10.490 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Beta-catenin-interacting ICAT | 0.54 | 36.0 | 3.82e-01 | 71.0% | 86.8% |
| 1lq7A00 | 1.20.1270.70 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle | 0.53 | 37.0 | 3.68e-01 | 98.4% | 68.7% |
| 7prrB01 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.53 | 37.0 | 2.82e-01 | 77.4% | 60.9% |
| 4a4kA01 | 1.20.1500.20 | Mainly Alpha › Up-down Bundle › YheA-like fold › | 0.50 | 41.0 | 3.51e-01 | 98.4% | 65.5% |