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URC17097.1
Arc-VirON548427__URC17097.1__X__00022
Identity
- Accession:
- ON548427 ↗
- Protein ID:
- URC17097.1 ↗
- Kingdom:
- archaea
Quality
70.3
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 3-110
Domain cluster:
representative
CATH (81)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2crbA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.74 | 50.0 | 5.31e-01 | 79.6% | 77.3% |
| 3u8vA00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.74 | 54.0 | 6.10e-01 | 93.5% | 100.0% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.73 | 56.0 | 5.82e-01 | 100.0% | 88.0% |
| 5wp3B00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.73 | 57.0 | 5.89e-01 | 83.3% | 97.1% |
| 3rkvA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.71 | 45.0 | 4.02e-01 | 71.3% | 46.3% |
| 5ziyA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.71 | 64.0 | 5.27e-01 | 100.0% | 73.2% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.70 | 64.0 | 6.35e-01 | 100.0% | 93.8% |
| 1tqgA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.70 | 60.0 | 6.13e-01 | 100.0% | 96.2% |
| 6t0bc02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.69 | 62.0 | 5.16e-01 | 100.0% | 67.0% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.69 | 51.0 | 5.06e-01 | 78.7% | 77.6% |
| 2jbwA01 | 1.20.1440.110 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase | 0.69 | 44.0 | 4.55e-01 | 75.0% | 68.0% |
| 7e5aB02 | 1.20.1000.10 | Mainly Alpha › Up-down Bundle › Signaling Protein - Interferon-induced Guanylate-binding Protein 1; Chain A, domain 1 › Guanylate-binding protein, C-terminal domain | 0.68 | 50.0 | 4.38e-01 | 85.2% | 50.6% |
| 6adqG01 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.68 | 62.0 | 5.25e-01 | 100.0% | 72.5% |
| 1i5nB00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.68 | 60.0 | 5.69e-01 | 100.0% | 82.3% |
| 2yevA03 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.68 | 61.0 | 5.12e-01 | 100.0% | 70.1% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.68 | 43.0 | 5.04e-01 | 72.2% | 93.2% |
| 3kyiA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.67 | 59.0 | 5.59e-01 | 100.0% | 80.5% |
| 1wcrA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.67 | 51.0 | 5.19e-01 | 79.6% | 96.1% |
| 2p61A00 | 1.20.120.490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain | 0.67 | 56.0 | 5.54e-01 | 97.2% | 86.8% |
| 2yksA02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.67 | 60.0 | 5.85e-01 | 100.0% | 96.6% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.66 | 49.0 | 4.75e-01 | 77.8% | 73.0% |
| 2ib0A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.66 | 50.0 | 4.63e-01 | 78.7% | 95.6% |
| 4dwlA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.66 | 49.0 | 4.98e-01 | 78.7% | 85.2% |
| 3iqcA00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.66 | 58.0 | 5.63e-01 | 100.0% | 88.2% |
| 2xq9A02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.66 | 60.0 | 5.80e-01 | 100.0% | 91.7% |
| 1h6gA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.66 | 58.0 | 5.62e-01 | 100.0% | 97.6% |
| 2v6yA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.66 | 43.0 | 4.98e-01 | 75.9% | 96.0% |
| 2jx0A00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.65 | 59.0 | 5.53e-01 | 100.0% | 88.5% |
| 1x8zB00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.65 | 48.0 | 4.39e-01 | 77.8% | 66.0% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.65 | 49.0 | 4.84e-01 | 80.6% | 86.3% |
| 3f4mA00 | 1.20.1440.160 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like | 0.64 | 56.0 | 5.00e-01 | 97.2% | 68.8% |
| 3wscA00 | 1.20.1420.20 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › M75 peptidase, HXXE motif | 0.64 | 58.0 | 4.42e-01 | 100.0% | 46.2% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.64 | 57.0 | 5.20e-01 | 100.0% | 77.6% |
| 3edvB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 48.0 | 4.51e-01 | 80.6% | 75.0% |
| 3ihuA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.64 | 51.0 | 4.76e-01 | 99.1% | 67.6% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.64 | 48.0 | 4.94e-01 | 79.6% | 97.1% |
| 1ug7A00 | 1.20.120.360 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Axin interactor, dorsalization-associated protein, N-terminal domain | 0.63 | 57.0 | 5.40e-01 | 100.0% | 85.2% |
| 2b1eA04 | 1.20.1280.170 | Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 | 0.63 | 47.0 | 4.48e-01 | 78.7% | 70.1% |
| 1vi0A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.63 | 48.0 | 4.33e-01 | 79.6% | 60.7% |
| 1m2vB01 | 1.20.120.730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Sec23/Sec24 helical domain | 0.63 | 54.0 | 4.71e-01 | 95.4% | 81.1% |
| 1orjD00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.63 | 56.0 | 5.34e-01 | 100.0% | 90.4% |
| 2fbnA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.63 | 42.0 | 3.73e-01 | 77.8% | 47.7% |
| 2cdqA02 | 1.20.120.1320 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartokinase, catalytic domain | 0.63 | 48.0 | 5.07e-01 | 90.7% | 92.8% |
| 1eq1A00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.62 | 55.0 | 4.85e-01 | 100.0% | 67.5% |
| 3e0sA00 | 1.40.20.10 | Mainly Alpha › Alpha solenoid › CHAD domain › CHAD domain | 0.62 | 56.0 | 4.10e-01 | 100.0% | 48.0% |
| 1e2aA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.62 | 47.0 | 4.83e-01 | 79.6% | 95.1% |
| 1q0gA00 | 1.20.120.400 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase | 0.62 | 53.0 | 5.21e-01 | 94.4% | 89.7% |
| 1wfdA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.62 | 39.0 | 4.17e-01 | 72.2% | 73.1% |
| 2rfqC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.62 | 45.0 | 3.85e-01 | 75.9% | 77.1% |
| 4ecgA00 | 1.20.1420.20 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › M75 peptidase, HXXE motif | 0.61 | 55.0 | 3.81e-01 | 100.0% | 41.0% |
| 3dzaA01 | 1.20.120.1940 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YfdX protein domain | 0.61 | 52.0 | 5.11e-01 | 92.6% | 87.2% |
| 6nmnA02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.61 | 54.0 | 5.17e-01 | 100.0% | 88.3% |
| 2w31A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.61 | 45.0 | 4.05e-01 | 78.7% | 85.5% |
| 3c18A02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.60 | 54.0 | 5.32e-01 | 100.0% | 91.5% |
| 4k5yA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 51.0 | 3.99e-01 | 96.3% | 87.5% |
| 2jqqA00 | 1.20.58.1240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 44.0 | 3.97e-01 | 78.7% | 55.8% |
| 3v5uA02 | 1.20.1420.30 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › NCX, central ion-binding region | 0.59 | 52.0 | 4.22e-01 | 100.0% | 49.8% |
| 4agsB04 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.59 | 46.0 | 4.30e-01 | 83.3% | 95.5% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.59 | 44.0 | 4.65e-01 | 79.6% | 98.9% |
| 4nqfA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.58 | 52.0 | 4.73e-01 | 100.0% | 91.0% |
| 4g10A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.58 | 45.0 | 4.26e-01 | 85.2% | 92.6% |
| 3frrA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.58 | 48.0 | 3.99e-01 | 88.9% | 82.8% |
| 2a9uA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.58 | 39.0 | 3.79e-01 | 74.1% | 59.5% |
| 2hsbA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.58 | 51.0 | 4.84e-01 | 97.2% | 95.2% |
| 3i2fA02 | 1.10.3020.10 | Mainly Alpha › Orthogonal Bundle › alpha-amino acid ester hydrolase ( Helical cap domain) › alpha-amino acid ester hydrolase ( Helical cap domain) | 0.58 | 36.0 | 3.85e-01 | 77.8% | 70.5% |
| 2rd3D00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.57 | 50.0 | 4.03e-01 | 97.2% | 80.3% |
| 3efoB01 | 1.20.120.730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Sec23/Sec24 helical domain | 0.57 | 49.0 | 4.41e-01 | 95.4% | 72.8% |
| 4q5nA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.57 | 42.0 | 4.18e-01 | 77.8% | 76.8% |
| 3ggyA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.57 | 47.0 | 3.96e-01 | 90.7% | 85.5% |
| 4agsA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.56 | 45.0 | 4.20e-01 | 86.1% | 92.6% |
| 1n4kA02 | 1.25.10.30 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › IP3 receptor type 1 binding core, RIH domain | 0.56 | 43.0 | 3.86e-01 | 80.6% | 89.2% |
| 3r2qA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.56 | 39.0 | 3.93e-01 | 74.1% | 72.6% |
| 2o7tA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 41.0 | 3.47e-01 | 79.6% | 45.4% |
| 1wolA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.55 | 48.0 | 4.65e-01 | 99.1% | 98.4% |
| 3o7pA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.54 | 47.0 | 3.78e-01 | 97.2% | 94.5% |
| 3h3mA00 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.54 | 38.0 | 4.13e-01 | 78.7% | 91.0% |
| 1cnt200 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.53 | 47.0 | 4.44e-01 | 100.0% | 95.4% |
| 4w66B00 | 1.20.1050.130 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.52 | 41.0 | 3.34e-01 | 87.0% | 60.0% |
| 7f16R01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.52 | 46.0 | 3.46e-01 | 100.0% | 76.5% |
| 4i4cB00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.52 | 45.0 | 3.10e-01 | 97.2% | 84.9% |
| 7lb8B01 | 1.10.3470.10 | Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC | 0.51 | 44.0 | 3.25e-01 | 100.0% | 46.4% |
ECOD (91)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3802176 | 604.16.1.3 ↗ | alpha bundles › Spectrin repeat-like › Hypothetical membrane protein Ta0354, soluble domain › Hypothetical membrane protein Ta0354, soluble domain › Vwaint | 0.81 | 68.0 | 6.89e-01 | 97.2% | 90.5% |
| 3438249 | 601.18.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 | 0.81 | 64.0 | 6.70e-01 | 97.2% | 91.0% |
| 5060515 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.80 | 60.0 | 4.64e-01 | 77.8% | 73.8% |
| 4018342 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.76 | 66.0 | 6.60e-01 | 100.0% | 91.8% |
| 5063888 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.76 | 60.0 | 4.73e-01 | 84.3% | 77.5% |
| 5044488 | 7064.1.1.0 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 | 0.75 | 69.0 | 5.94e-01 | 100.0% | 67.9% |
| 5013911 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.75 | 59.0 | 4.61e-01 | 84.3% | 80.4% |
| 2642640 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.73 | 56.0 | 5.01e-01 | 80.6% | 59.7% |
| 2060764 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.72 | 55.0 | 5.18e-01 | 79.6% | 68.8% |
| 3652677 | 601.18.1.13 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Vwaint | 0.71 | 65.0 | 6.38e-01 | 99.1% | 92.2% |
| 3790404 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.71 | 47.0 | 3.84e-01 | 78.7% | 37.4% |
| 4974835 | 3281.1.1.0 ↗ | alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related | 0.70 | 64.0 | 3.97e-01 | 100.0% | 23.0% |
| 4500523 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.70 | 62.0 | 5.74e-01 | 100.0% | 76.4% |
| 3860480 | 109.4.1.1444 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_14, TPR_16 | 0.69 | 47.0 | 3.81e-01 | 77.8% | 37.0% |
| 3693766 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.69 | 59.0 | 5.83e-01 | 94.4% | 95.7% |
| 3407072 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.69 | 47.0 | 5.34e-01 | 78.7% | 96.2% |
| 4927882 | 601.18.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 | 0.68 | 58.0 | 5.76e-01 | 97.2% | 90.0% |
| 4031805 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.68 | 60.0 | 5.96e-01 | 96.3% | 100.0% |
| 4927880 | 601.16.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase | 0.67 | 58.0 | 5.76e-01 | 100.0% | 90.4% |
| 3390932 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.67 | 48.0 | 5.19e-01 | 80.6% | 90.0% |
| 4604117 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.67 | 58.0 | 5.84e-01 | 96.3% | 100.0% |
| 3255556 | 601.1.1.7 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B | 0.66 | 59.0 | 4.35e-01 | 100.0% | 57.2% |
| 3264408 | 3745.1.1.1 ↗ | alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Na_Ca_ex | 0.66 | 58.0 | 4.27e-01 | 100.0% | 60.0% |
| 4078639 | 3281.1.1.1 ↗ | alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related › Proton_antipo_M | 0.66 | 58.0 | 3.82e-01 | 98.1% | 25.7% |
| 3482166 | 5039.1.1.0 ↗ | alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like | 0.66 | 53.0 | 4.68e-01 | 87.0% | 72.3% |
| 5054956 | 7064.1.1.0 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 | 0.66 | 58.0 | 5.69e-01 | 100.0% | 90.8% |
| 4009351 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.66 | 59.0 | 4.91e-01 | 100.0% | 93.7% |
| 3621994 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.66 | 46.0 | 4.25e-01 | 79.6% | 57.0% |
| 3865367 | 196.1.1.0 ↗ | alpha bundles › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS | 0.65 | 52.0 | 4.03e-01 | 98.1% | 39.6% |
| 3236489 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.65 | 60.0 | 5.56e-01 | 100.0% | 80.7% |
| 4803706 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.65 | 48.0 | 4.21e-01 | 78.7% | 53.3% |
| 3371182 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.65 | 48.0 | 4.89e-01 | 77.8% | 81.0% |
| 3829016 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.65 | 48.0 | 4.63e-01 | 78.7% | 69.6% |
| 3282653 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.64 | 55.0 | 4.67e-01 | 98.1% | 89.5% |
| 3270441 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.63 | 42.0 | 4.79e-01 | 75.9% | 96.0% |
| 3703129 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.63 | 47.0 | 3.88e-01 | 78.7% | 84.0% |
| 3314927 | 7064.1.1.5 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › ALMT | 0.63 | 51.0 | 4.50e-01 | 100.0% | 58.2% |
| 3408380 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.63 | 47.0 | 4.86e-01 | 78.7% | 92.0% |
| 54592 | 601.13.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS | 0.63 | 56.0 | 5.37e-01 | 100.0% | 91.9% |
| 3945700 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.63 | 55.0 | 4.68e-01 | 99.1% | 95.7% |
| 3744 | 601.13.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS › FliS | 0.62 | 55.0 | 5.31e-01 | 100.0% | 89.7% |
| 3958019 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.62 | 54.0 | 4.38e-01 | 98.1% | 78.6% |
| 3740421 | 603.1.1.98 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE, Syntaxin_2 | 0.62 | 45.0 | 3.65e-01 | 74.1% | 74.1% |
| 5053013 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.62 | 54.0 | 4.65e-01 | 100.0% | 95.1% |
| 4955893 | 109.10.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin | 0.62 | 49.0 | 4.02e-01 | 85.2% | 55.6% |
| 3415309 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.62 | 54.0 | 4.67e-01 | 99.1% | 97.8% |
| 3925326 | 601.11.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0.62 | 55.0 | 4.80e-01 | 100.0% | 64.1% |
| 3590809 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.62 | 56.0 | 4.38e-01 | 100.0% | 67.4% |
| 3268622 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.61 | 44.0 | 4.53e-01 | 80.6% | 78.1% |
| 4014243 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.61 | 54.0 | 4.32e-01 | 100.0% | 82.2% |
| 4401245 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.61 | 55.0 | 4.44e-01 | 100.0% | 86.1% |
| 1839916 | 601.7.1.13 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › YgxA-like_sub_bind | 0.61 | 54.0 | 5.46e-01 | 100.0% | 97.2% |
| 5058288 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.61 | 53.0 | 4.60e-01 | 98.1% | 98.9% |
| 4991040 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.61 | 53.0 | 4.49e-01 | 99.1% | 92.1% |
| 5072449 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.61 | 42.0 | 4.60e-01 | 77.8% | 86.7% |
| 5009844 | 601.7.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › PaREP1 | 0.61 | 55.0 | 4.82e-01 | 100.0% | 89.4% |
| 5026259 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.61 | 54.0 | 4.43e-01 | 99.1% | 89.5% |
| 3471234 | 3832.1.1.1 ↗ | alpha bundles › Tumor necrosis factor alpha-induced protein 8-like protein 2 › Tumor necrosis factor alpha-induced protein 8-like protein 2 › Tumor necrosis factor alpha-induced protein 8-like protein 2 › DUF758 | 0.61 | 51.0 | 4.37e-01 | 95.4% | 93.5% |
| 3975942 | 601.4.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TorS_sensor_domain | 0.60 | 53.0 | 5.05e-01 | 100.0% | 83.1% |
| 3739736 | 5050.1.1.23 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › CLN3 | 0.60 | 46.0 | 3.96e-01 | 82.4% | 88.9% |
| 3500773 | 3832.1.1.1 ↗ | alpha bundles › Tumor necrosis factor alpha-induced protein 8-like protein 2 › Tumor necrosis factor alpha-induced protein 8-like protein 2 › Tumor necrosis factor alpha-induced protein 8-like protein 2 › DUF758 | 0.60 | 50.0 | 4.39e-01 | 95.4% | 58.3% |
| 3282854 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.60 | 52.0 | 4.29e-01 | 99.1% | 85.2% |
| 3872076 | 192.29.1.136 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Clusterin | 0.60 | 44.0 | 3.90e-01 | 76.9% | 71.6% |
| 3806852 | 109.62.1.3 ↗ | alpha superhelices › Repetitive alpha hairpins › AFF4 C-terminal homology domain › AFF4 C-terminal homology domain › THD_CWZF3-5-7 | 0.60 | 53.0 | 4.35e-01 | 100.0% | 79.8% |
| 3690080 | 603.5.1.0 ↗ | alpha bundles › STAT-like › FlgN-like › FlgN-like | 0.60 | 45.0 | 4.35e-01 | 79.6% | 79.8% |
| 3968384 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.60 | 52.0 | 4.29e-01 | 99.1% | 83.4% |
| 3291550 | 191.1.1.49 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_13_2 | 0.59 | 51.0 | 4.65e-01 | 94.4% | 76.6% |
| 3704190 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.59 | 52.0 | 4.16e-01 | 100.0% | 78.3% |
| 3899959 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.59 | 44.0 | 4.52e-01 | 79.6% | 97.1% |
| 4977941 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.59 | 52.0 | 4.30e-01 | 100.0% | 93.0% |
| 3540024 | 5001.1.1.3 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 | 0.58 | 52.0 | 3.89e-01 | 100.0% | 80.0% |
| 4222857 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.58 | 50.0 | 4.21e-01 | 98.1% | 87.0% |
| 4663299 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.58 | 52.0 | 4.15e-01 | 100.0% | 81.8% |
| 4937680 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.58 | 52.0 | 4.37e-01 | 100.0% | 91.9% |
| 5037363 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.58 | 50.0 | 4.30e-01 | 99.1% | 91.4% |
| 3505833 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.58 | 51.0 | 4.33e-01 | 100.0% | 93.5% |
| 5014403 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.58 | 51.0 | 4.31e-01 | 100.0% | 94.1% |
| 3872220 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.58 | 43.0 | 4.33e-01 | 80.6% | 92.7% |
| 3570756 | 3883.1.1.0 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain | 0.57 | 49.0 | 4.12e-01 | 100.0% | 53.0% |
| 4946275 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.57 | 43.0 | 3.30e-01 | 80.6% | 92.7% |
| 3759765 | 5050.1.1.11 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UNC-93 | 0.57 | 50.0 | 4.05e-01 | 100.0% | 78.2% |
| 4971727 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.57 | 49.0 | 4.14e-01 | 99.1% | 88.7% |
| 5063260 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.57 | 50.0 | 5.04e-01 | 99.1% | 99.1% |
| 3263375 | 109.4.1.210 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_19 | 0.56 | 44.0 | 3.73e-01 | 83.3% | 53.3% |
| 5067694 | 3883.1.1.1 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf | 0.56 | 49.0 | 3.98e-01 | 100.0% | 88.2% |
| 3181183 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.55 | 47.0 | 3.88e-01 | 99.1% | 84.1% |
| 5071763 | 601.7.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN | 0.55 | 50.0 | 4.45e-01 | 100.0% | 86.9% |
| 4958226 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.55 | 44.0 | 3.31e-01 | 89.8% | 80.0% |
| 3397682 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 47.0 | 3.81e-01 | 99.1% | 81.3% |
| 3279571 | 5065.1.1.2 ↗ | alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › FecCD | 0.53 | 47.0 | 3.35e-01 | 99.1% | 43.5% |
| 4034080 | 5065.1.1.2 ↗ | alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › FecCD | 0.53 | 47.0 | 3.34e-01 | 97.2% | 46.2% |