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UVF62251.1
Arc-VirON649698__UVF62251.1__X__00047
Identity
- Accession:
- ON649698 ↗
- Protein ID:
- UVF62251.1 ↗
- Kingdom:
- archaea
Quality
65.7
mean pLDDT
Taxonomy
Heunggongvirae›
Uroviricota›
Caudoviricetes›
Juravirales›
Yanlukaviridae›
Sweetvirus›
Nitrososphaeria_virus_YSH_1032793
TaxID: 3071320
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 7-62
Domain cluster:
representative
CATH (42)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.89 | 83.0 | 6.34e-01 | 100.0% | 55.2% |
| 2gsvA00 | 6.10.140.40 | Special › Helix non-globular › Helix Hairpins › | 0.85 | 66.0 | 6.18e-01 | 82.1% | 68.7% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.79 | 58.0 | 5.09e-01 | 96.4% | 52.9% |
| 4nv0A02 | 1.10.150.340 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Pyrimidine 5'-nucleotidase (UMPH-1), N-terminal domain | 0.78 | 62.0 | 5.49e-01 | 96.4% | 59.8% |
| 3n5lA03 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.78 | 67.0 | 6.68e-01 | 98.2% | 93.0% |
| 4fppB01 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.78 | 68.0 | 6.34e-01 | 100.0% | 90.1% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.75 | 66.0 | 5.94e-01 | 100.0% | 76.9% |
| 1yq1A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.75 | 66.0 | 5.25e-01 | 98.2% | 51.8% |
| 1z0jB00 | 4.10.860.20 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain | 0.75 | 61.0 | 6.35e-01 | 100.0% | 100.0% |
| 4ijjB00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.73 | 63.0 | 4.88e-01 | 100.0% | 67.7% |
| 5dn6J00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.73 | 62.0 | 5.75e-01 | 100.0% | 83.8% |
| 3d36B02 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.73 | 60.0 | 5.86e-01 | 91.1% | 91.8% |
| 4nb5B02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.72 | 63.0 | 6.04e-01 | 100.0% | 100.0% |
| 2kw6A00 | 6.10.140.1300 | Special › Helix non-globular › Helix Hairpins › | 0.72 | 59.0 | 5.68e-01 | 92.9% | 78.5% |
| 2gtsA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.71 | 63.0 | 5.69e-01 | 100.0% | 72.7% |
| 2e5yA02 | 1.20.5.440 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › ATP synthase delta/epsilon subunit, C-terminal domain | 0.70 | 49.0 | 5.36e-01 | 73.2% | 100.0% |
| 3mq1A01 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 59.0 | 5.12e-01 | 100.0% | 60.9% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.69 | 58.0 | 3.90e-01 | 100.0% | 24.1% |
| 1b48A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.69 | 58.0 | 4.82e-01 | 100.0% | 51.4% |
| 3qc1A01 | 1.25.40.540 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TAP42-like family | 0.69 | 54.0 | 4.04e-01 | 89.3% | 32.5% |
| 6vq6G02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.69 | 59.0 | 4.18e-01 | 100.0% | 88.0% |
| 3i2fA02 | 1.10.3020.10 | Mainly Alpha › Orthogonal Bundle › alpha-amino acid ester hydrolase ( Helical cap domain) › alpha-amino acid ester hydrolase ( Helical cap domain) | 0.68 | 53.0 | 4.49e-01 | 87.5% | 50.5% |
| 2cazC00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.68 | 57.0 | 5.53e-01 | 94.6% | 87.5% |
| 1fs0G02 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.67 | 58.0 | 5.04e-01 | 100.0% | 77.5% |
| 1v9dB00 | 1.20.58.2220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Formin, FH2 domain | 0.67 | 59.0 | 3.70e-01 | 100.0% | 61.7% |
| 2f2gA00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.67 | 56.0 | 3.86e-01 | 100.0% | 27.4% |
| 1vx7301 | 1.10.287.310 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.67 | 58.0 | 5.33e-01 | 100.0% | 78.4% |
| 7nc3F01 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.66 | 56.0 | 4.55e-01 | 100.0% | 49.1% |
| 1m62A00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.66 | 53.0 | 4.71e-01 | 98.2% | 60.9% |
| 1gaxA05 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.65 | 53.0 | 4.90e-01 | 91.1% | 72.6% |
| 1hqoA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.65 | 54.0 | 4.28e-01 | 100.0% | 44.3% |
| 7ymiZ01 | 1.10.287.740 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre | 0.64 | 52.0 | 5.19e-01 | 96.4% | 91.4% |
| 4fzsA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.64 | 52.0 | 3.63e-01 | 96.4% | 27.3% |
| 1s5jA04 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.63 | 53.0 | 5.19e-01 | 98.2% | 86.9% |
| 1f45B00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.63 | 53.0 | 4.15e-01 | 100.0% | 67.7% |
| 4ivfA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.63 | 51.0 | 4.25e-01 | 100.0% | 50.0% |
| 6t4hA03 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.62 | 54.0 | 3.90e-01 | 100.0% | 33.1% |
| 3rklA00 | 6.10.140.1640 | Special › Helix non-globular › Helix Hairpins › | 0.62 | 53.0 | 4.77e-01 | 100.0% | 72.5% |
| 1x4tA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.61 | 50.0 | 4.98e-01 | 98.2% | 91.4% |
| 2b3tB01 | 6.10.140.1980 | Special › Helix non-globular › Helix Hairpins › | 0.59 | 45.0 | 4.37e-01 | 85.7% | 95.4% |
| 2lpeA01 | 6.10.140.1120 | Special › Helix non-globular › Helix Hairpins › | 0.58 | 49.0 | 4.48e-01 | 98.2% | 82.1% |
| 5b7cA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.57 | 46.0 | 3.88e-01 | 100.0% | 54.1% |
ECOD (50)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4354962 | 3390.1.1.0 ↗ | extended segments › Photosystem II reaction center protein T, PsbT › Photosystem II reaction center protein T, PsbT › Photosystem II reaction center protein T, PsbT | 0.92 | 76.0 | 8.04e-01 | 87.5% | 98.0% |
| 3389059 | 4082.1.1.1 ↗ | alpha duplicates or obligate multimers › Hairy Orange domain › Hairy Orange domain › Hairy Orange domain › Hairy_orange | 0.92 | 81.0 | 8.25e-01 | 96.4% | 96.4% |
| 3921951 | 632.8.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 | 0.92 | 72.0 | 6.09e-01 | 82.1% | 56.5% |
| 3938243 | 3065.1.1.1 ↗ | alpha bundles › Fatty acid- and retinoid-binding proteins › Fatty acid- and retinoid-binding proteins › Fatty acid- and retinoid-binding proteins › ANIS5_cation-bd | 0.91 | 84.0 | 5.34e-01 | 100.0% | 23.7% |
| 3214189 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.91 | 84.0 | 6.65e-01 | 100.0% | 54.3% |
| 3921001 | 109.4.1.1472 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Tho2, Thoc2, THOC2_N | 0.90 | 83.0 | 4.43e-01 | 100.0% | 5.8% |
| 4562953 | 2004.1.1.43 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SRP54 | 0.89 | 83.0 | 5.11e-01 | 100.0% | 28.4% |
| 4241570 | 192.15.1.91 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › COX4_pro | 0.89 | 82.0 | 7.04e-01 | 100.0% | 70.6% |
| 4034613 | 5058.1.1.4 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › COX4_pro | 0.89 | 82.0 | 6.88e-01 | 100.0% | 67.8% |
| 3748229 | 3826.1.1.0 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) | 0.89 | 82.0 | 6.31e-01 | 100.0% | 48.7% |
| 3986220 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.88 | 81.0 | 6.26e-01 | 100.0% | 50.4% |
| 4469698 | 3718.1.1.15 ↗ | alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT › COX4_pro | 0.88 | 81.0 | 6.79e-01 | 100.0% | 67.8% |
| 5074225 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.86 | 79.0 | 6.63e-01 | 100.0% | 64.4% |
| 3805159 | 4099.1.1.11 ↗ | a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › Med14 | 0.85 | 77.0 | 6.26e-01 | 100.0% | 60.0% |
| 3992791 | 3843.1.1.0 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K | 0.84 | 76.0 | 6.31e-01 | 100.0% | 61.1% |
| 3303117 | 605.4.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein | 0.84 | 76.0 | 6.56e-01 | 100.0% | 65.9% |
| 4660205 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.83 | 75.0 | 5.59e-01 | 100.0% | 43.7% |
| 3248423 | 109.42.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › E3 ubiquitin-protein ligase SHPRH first helical domain › E3 ubiquitin-protein ligase SHPRH first helical domain › SHPRH_helical-1st | 0.83 | 67.0 | 4.44e-01 | 96.4% | 23.9% |
| 3834200 | 616.1.1.0 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain | 0.82 | 68.0 | 6.30e-01 | 91.1% | 72.9% |
| 4235299 | 310.2.1.1 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF | 0.81 | 73.0 | 5.00e-01 | 100.0% | 33.2% |
| 4026047 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.80 | 72.0 | 6.23e-01 | 100.0% | 65.9% |
| 4010684 | 3615.1.1.0 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain | 0.79 | 71.0 | 4.21e-01 | 100.0% | 15.4% |
| 3362460 | 304.60.1.6 ↗ | a+b two layers › Alpha-beta plaits › Ribosomal protein L10-like › Ribosomal protein L10-like › KIP1 | 0.78 | 70.0 | 6.34e-01 | 100.0% | 80.0% |
| 3725615 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.78 | 69.0 | 6.05e-01 | 96.4% | 67.5% |
| 3584915 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.78 | 60.0 | 5.18e-01 | 83.9% | 54.1% |
| 4003615 | 5054.1.1.59 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans, Ion_trans_2 | 0.78 | 68.0 | 4.51e-01 | 100.0% | 42.7% |
| 3223457 | 101.1.2.661 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_9, POLR3C_WHD | 0.78 | 68.0 | 4.32e-01 | 98.2% | 35.7% |
| 4009690 | 7523.1.1.25 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Phosphonate-bd | 0.78 | 67.0 | 4.56e-01 | 100.0% | 27.2% |
| 3399070 | 4082.1.1.1 ↗ | alpha duplicates or obligate multimers › Hairy Orange domain › Hairy Orange domain › Hairy Orange domain › Hairy_orange | 0.75 | 57.0 | 5.76e-01 | 83.9% | 87.3% |
| 3839497 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.75 | 65.0 | 5.64e-01 | 96.4% | 92.9% |
| 3165232 | 1078.1.1.0 ↗ | extended segments › Bd-type quinol oxidase transmembrane helix subunit › Bd-type quinol oxidase transmembrane helix subunit › Bd-type quinol oxidase transmembrane helix subunit | 0.75 | 56.0 | 6.14e-01 | 83.9% | 100.0% |
| 3404270 | 377.1.1.0 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like | 0.75 | 67.0 | 5.09e-01 | 100.0% | 98.5% |
| 4943086 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.75 | 61.0 | 5.70e-01 | 89.3% | 72.9% |
| 3283655 | 3812.1.1.0 ↗ | alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE | 0.74 | 60.0 | 6.23e-01 | 100.0% | 100.0% |
| 4968943 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.72 | 59.0 | 5.25e-01 | 94.6% | 68.2% |
| 3172784 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.72 | 62.0 | 5.15e-01 | 100.0% | 59.0% |
| 3716018 | 3877.1.1.1 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC › 60KD_IMP | 0.72 | 58.0 | 3.89e-01 | 91.1% | 22.2% |
| 5018387 | 604.18.1.0 ↗ | alpha bundles › Spectrin repeat-like › Triple-helical domain in regulatory ATPase variant A (RavA) › Triple-helical domain in regulatory ATPase variant A (RavA) | 0.72 | 62.0 | 5.11e-01 | 100.0% | 56.2% |
| 4001186 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.72 | 58.0 | 4.07e-01 | 100.0% | 27.4% |
| 4043979 | 3812.1.1.4 ↗ | alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE › GrpE | 0.71 | 59.0 | 5.84e-01 | 96.4% | 86.7% |
| 3417475 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.70 | 63.0 | 3.73e-01 | 100.0% | 14.2% |
| 4819006 | 2004.1.1.5 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran | 0.70 | 59.0 | 3.83e-01 | 100.0% | 20.9% |
| 3509923 | 6103.1.1.0 ↗ | alpha bundles › Death domain-associated protein 6 histone binding domain › Death domain-associated protein 6 histone binding domain › Death domain-associated protein 6 histone binding domain | 0.69 | 59.0 | 4.10e-01 | 98.2% | 28.6% |
| 3687766 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.69 | 60.0 | 4.02e-01 | 100.0% | 26.2% |
| 3482751 | 192.1.1.0 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain | 0.69 | 58.0 | 5.57e-01 | 96.4% | 87.7% |
| 3349325 | 5086.1.1.135 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › DUF7615 | 0.68 | 60.0 | 5.36e-01 | 100.0% | 80.0% |
| 4336724 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.67 | 58.0 | 4.66e-01 | 98.2% | 89.1% |
| 3323862 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.66 | 52.0 | 4.76e-01 | 100.0% | 63.7% |
| 4671 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.64 | 54.0 | 4.46e-01 | 98.2% | 90.0% |
| 3794577 | 3331.1.1.14 ↗ | a+b two layers › Uncharacterized protein yibL › Uncharacterized protein yibL › Uncharacterized protein yibL › CHDCT2 | 0.62 | 52.0 | 4.67e-01 | 100.0% | 67.1% |