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ON854455.1__UUG68605.1__YPHTV1_00043__00043
Bact-VirON854455.1__UUG68605.1__YPHTV1_00043__00043
Identity
- Accession:
- ON854455 ↗
- Kingdom:
- phage
Quality
88.8
mean pLDDT
Cluster
View cluster (13 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-64
Domain cluster:
representative
CATH (78)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1vf7A03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.86 | 72.0 | 7.42e-01 | 92.2% | 95.0% |
| 3rh3A01 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.86 | 66.0 | 5.06e-01 | 92.2% | 39.1% |
| 1x04A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.85 | 72.0 | 4.90e-01 | 93.8% | 29.0% |
| 3uo2B02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.83 | 63.0 | 5.72e-01 | 92.2% | 61.9% |
| 3nkzA00 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.82 | 63.0 | 5.41e-01 | 93.8% | 53.6% |
| 3sjqC00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.81 | 69.0 | 6.35e-01 | 93.8% | 72.5% |
| 1sg2A00 | 3.30.910.20 | Alpha Beta › 2-Layer Sandwich › Protein Binding, DinI Protein; Chain A › Skp domain | 0.81 | 62.0 | 4.69e-01 | 93.8% | 36.9% |
| 1fxkB00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.80 | 68.0 | 5.64e-01 | 92.2% | 63.3% |
| 2ke4A00 | 6.10.140.470 | Special › Helix non-globular › Helix Hairpins › | 0.80 | 68.0 | 5.86e-01 | 92.2% | 67.3% |
| 1z0jB00 | 4.10.860.20 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain | 0.80 | 57.0 | 6.23e-01 | 87.5% | 94.1% |
| 4e4eA01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.80 | 69.0 | 6.67e-01 | 93.8% | 85.9% |
| 1ni3A03 | 1.10.150.300 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Obg-related GTPase Ych/YyaF, coiled-coil domain | 0.79 | 63.0 | 5.52e-01 | 84.4% | 64.8% |
| 1ku9A02 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.79 | 69.0 | 6.95e-01 | 93.8% | 98.4% |
| 2jexA01 | 1.10.287.30 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 | 0.79 | 67.0 | 5.74e-01 | 92.2% | 60.4% |
| 2ic6A00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.78 | 68.0 | 6.54e-01 | 93.8% | 87.3% |
| 1nt2B02 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.77 | 65.0 | 6.43e-01 | 92.2% | 97.0% |
| 2rkhA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.77 | 63.0 | 5.95e-01 | 89.1% | 80.3% |
| 4l0rB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 65.0 | 6.24e-01 | 93.8% | 90.4% |
| 3txsC01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.76 | 64.0 | 6.05e-01 | 92.2% | 78.7% |
| 4kzsA02 | 6.10.140.1870 | Special › Helix non-globular › Helix Hairpins › | 0.76 | 64.0 | 6.25e-01 | 93.8% | 84.3% |
| 5y06A01 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.76 | 64.0 | 4.34e-01 | 93.8% | 45.4% |
| 3nrxA00 | 1.20.58.1520 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 67.0 | 5.37e-01 | 100.0% | 68.3% |
| 1fs0G02 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.74 | 63.0 | 5.66e-01 | 93.8% | 73.0% |
| 6r1nA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.74 | 62.0 | 5.29e-01 | 92.2% | 60.2% |
| 4dylA02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.74 | 62.0 | 5.40e-01 | 93.8% | 61.7% |
| 2yv9B02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.74 | 65.0 | 5.00e-01 | 95.3% | 84.3% |
| 4ijjB00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.74 | 63.0 | 4.95e-01 | 93.8% | 47.7% |
| 2p4vA01 | 1.10.287.180 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain | 0.73 | 59.0 | 5.58e-01 | 89.1% | 89.5% |
| 2dw4A03 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.72 | 61.0 | 5.21e-01 | 92.2% | 83.2% |
| 3d85C00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.72 | 61.0 | 4.75e-01 | 92.2% | 96.2% |
| 2e9xA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 61.0 | 4.85e-01 | 93.8% | 68.0% |
| 2bdeA03 | 1.20.58.1160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 60.0 | 5.70e-01 | 93.8% | 79.2% |
| 3l1nA01 | 6.10.140.790 | Special › Helix non-globular › Helix Hairpins › | 0.71 | 53.0 | 5.77e-01 | 84.4% | 100.0% |
| 3okqA00 | 1.20.58.1540 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain | 0.71 | 59.0 | 4.77e-01 | 93.8% | 66.4% |
| 3r84B00 | 6.10.280.160 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 | 0.71 | 60.0 | 5.60e-01 | 93.8% | 82.5% |
| 4i0xG00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.70 | 59.0 | 5.77e-01 | 92.2% | 98.5% |
| 4o8sA02 | 1.20.58.1790 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › JHP933, helical tail domain | 0.69 | 56.0 | 4.71e-01 | 87.5% | 57.9% |
| 7xk2R01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.69 | 55.0 | 3.71e-01 | 92.2% | 21.9% |
| 3t9jA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.69 | 59.0 | 4.56e-01 | 96.9% | 46.5% |
| 3b2eF00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.68 | 54.0 | 5.50e-01 | 92.2% | 91.9% |
| 1pd3A00 | 1.10.287.230 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.68 | 51.0 | 5.41e-01 | 92.2% | 96.3% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.68 | 58.0 | 5.26e-01 | 100.0% | 79.1% |
| 1b3qA01 | 1.10.287.560 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain | 0.68 | 55.0 | 5.58e-01 | 90.6% | 93.5% |
| 4egwA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.68 | 55.0 | 4.59e-01 | 93.8% | 50.4% |
| 5nl6B01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 57.0 | 4.70e-01 | 96.9% | 71.1% |
| 1l8dA00 | 1.10.287.510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.67 | 54.0 | 4.75e-01 | 93.8% | 71.8% |
| 4n21E00 | 1.10.287.210 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.67 | 56.0 | 4.58e-01 | 93.8% | 51.2% |
| 2etnB01 | 1.10.287.180 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain | 0.67 | 55.0 | 5.24e-01 | 93.8% | 81.6% |
| 1j30A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.67 | 56.0 | 4.48e-01 | 100.0% | 90.1% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.67 | 56.0 | 4.82e-01 | 96.9% | 75.5% |
| 3kdqA00 | 6.10.320.10 | Special › Helix non-globular › Ferritin › | 0.66 | 54.0 | 4.20e-01 | 93.8% | 41.4% |
| 1s35A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 58.0 | 5.02e-01 | 100.0% | 87.1% |
| 1m5iA00 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.66 | 56.0 | 4.75e-01 | 93.8% | 66.7% |
| 4h63H01 | 1.20.58.1710 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 55.0 | 5.37e-01 | 95.3% | 100.0% |
| 3cqcA00 | 1.20.190.50 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › | 0.65 | 58.0 | 3.88e-01 | 100.0% | 28.7% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.65 | 52.0 | 4.95e-01 | 90.6% | 97.4% |
| 1fpoC02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.64 | 52.0 | 4.76e-01 | 93.8% | 69.2% |
| 1ydxA02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.64 | 53.0 | 4.82e-01 | 93.8% | 68.9% |
| 1qlbA03 | 1.20.58.100 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain | 0.63 | 50.0 | 4.21e-01 | 92.2% | 49.2% |
| 1wdhA02 | 1.10.720.60 | Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › | 0.63 | 42.0 | 3.62e-01 | 90.6% | 42.2% |
| 3h6pC00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.63 | 46.0 | 4.80e-01 | 82.8% | 92.9% |
| 1zoyA03 | 1.20.58.100 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain | 0.63 | 50.0 | 4.17e-01 | 90.6% | 49.6% |
| 2y1vA04 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.62 | 52.0 | 3.81e-01 | 96.9% | 49.2% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.62 | 50.0 | 4.71e-01 | 92.2% | 75.6% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.62 | 51.0 | 4.43e-01 | 93.8% | 62.7% |
| 1uurA01 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.62 | 53.0 | 4.55e-01 | 100.0% | 81.8% |
| 3lphC00 | 6.10.140.630 | Special › Helix non-globular › Helix Hairpins › | 0.61 | 48.0 | 5.02e-01 | 95.3% | 96.6% |
| 4dciA00 | 6.10.140.1110 | Special › Helix non-globular › Helix Hairpins › | 0.60 | 49.0 | 3.76e-01 | 89.1% | 39.5% |
| 4gzrC00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.60 | 49.0 | 5.07e-01 | 89.1% | 95.1% |
| 2fzlA02 | 6.10.140.1180 | Special › Helix non-globular › Helix Hairpins › | 0.59 | 50.0 | 5.10e-01 | 92.2% | 95.2% |
| 2kg7B00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.59 | 47.0 | 4.23e-01 | 92.2% | 61.9% |
| 3etvA02 | 1.20.58.2230 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Retrograde transport protein Dsl1, N-terminal domain | 0.59 | 48.0 | 3.39e-01 | 96.9% | 51.1% |
| 1zeeA01 | 1.20.58.600 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 50.0 | 4.19e-01 | 100.0% | 62.7% |
| 2x2vA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.57 | 48.0 | 4.71e-01 | 92.2% | 92.6% |
| 2i7uA00 | 6.10.250.1010 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.55 | 41.0 | 4.23e-01 | 87.5% | 87.1% |
| 4aybA07 | 1.10.132.30 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain | 0.55 | 49.0 | 3.98e-01 | 100.0% | 80.8% |
| 2oauA01 | 1.10.287.1260 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.54 | 49.0 | 4.17e-01 | 100.0% | 70.6% |
| 4kf9A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.53 | 43.0 | 3.45e-01 | 96.9% | 42.5% |
ECOD (51)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4602052 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.87 | 67.0 | 5.34e-01 | 92.2% | 43.3% |
| 3915380 | 192.5.1.25 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › PTHB1_hp | 0.82 | 71.0 | 6.25e-01 | 92.2% | 88.9% |
| 3614763 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.82 | 71.0 | 5.67e-01 | 93.8% | 80.8% |
| 3626769 | 192.5.1.14 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA | 0.81 | 65.0 | 5.77e-01 | 93.8% | 61.1% |
| 3999274 | 5086.1.1.102 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PTHB1_hp | 0.80 | 64.0 | 5.35e-01 | 93.8% | 52.4% |
| 3180581 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.79 | 68.0 | 6.12e-01 | 92.2% | 69.4% |
| 3507551 | 192.5.1.0 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat | 0.79 | 69.0 | 5.95e-01 | 93.8% | 72.6% |
| 4128407 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.79 | 67.0 | 5.54e-01 | 92.2% | 72.7% |
| 5066959 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.79 | 68.0 | 4.63e-01 | 93.8% | 45.1% |
| 3968763 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.79 | 60.0 | 5.58e-01 | 92.2% | 65.0% |
| 3602143 | 3755.3.1.305 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Rad50_zn_hook | 0.79 | 67.0 | 4.44e-01 | 92.2% | 95.8% |
| 3925617 | 192.5.1.14 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA | 0.77 | 61.0 | 5.56e-01 | 93.8% | 64.7% |
| 3519972 | 192.5.1.14 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA | 0.77 | 66.0 | 5.86e-01 | 93.8% | 76.7% |
| 3696658 | 3559.1.1.1 ↗ | a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Med22 | 0.76 | 65.0 | 5.07e-01 | 92.2% | 56.2% |
| 3734442 | 192.8.1.35 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › DUF6594 | 0.76 | 65.0 | 5.09e-01 | 93.8% | 47.7% |
| 3715876 | 2004.1.1.481 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_29 | 0.76 | 66.0 | 3.98e-01 | 95.3% | 25.7% |
| 3608116 | 5086.1.1.177 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › KIF9 | 0.75 | 66.0 | 4.92e-01 | 93.8% | 42.8% |
| 3875083 | 3291.1.1.218 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › KELK | 0.75 | 64.0 | 3.89e-01 | 93.8% | 19.7% |
| 3711734 | 3755.3.1.297 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF9 | 0.75 | 65.0 | 4.72e-01 | 93.8% | 37.6% |
| 3264174 | 622.4.1.58 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › PF26756 | 0.75 | 63.0 | 5.83e-01 | 92.2% | 73.8% |
| 4312324 | 605.1.1.306 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › PF30649 | 0.75 | 64.0 | 6.06e-01 | 93.8% | 88.0% |
| 3772767 | 5086.1.1.87 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING | 0.75 | 64.0 | 5.08e-01 | 93.8% | 55.2% |
| 3642682 | 603.1.1.5 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N | 0.74 | 68.0 | 5.51e-01 | 100.0% | 86.1% |
| 3553813 | 3291.1.1.82 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › ING | 0.74 | 63.0 | 5.03e-01 | 93.8% | 55.2% |
| 3861615 | 150.1.1.190 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › SAP130_C | 0.74 | 62.0 | 5.32e-01 | 92.2% | 59.0% |
| 4572974 | 3922.1.1.79 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › SAP130_C | 0.73 | 62.0 | 5.05e-01 | 92.2% | 51.3% |
| 3673003 | 3922.1.1.254 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › NET2A_C | 0.73 | 60.0 | 4.80e-01 | 90.6% | 74.4% |
| 4798159 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.73 | 62.0 | 5.87e-01 | 93.8% | 78.9% |
| 3004240 | 4207.1.1.1 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) › Med21 | 0.72 | 60.0 | 4.87e-01 | 92.2% | 48.4% |
| 3201136 | 207.1.1.0 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats | 0.72 | 61.0 | 3.88e-01 | 93.8% | 19.7% |
| 3984060 | 1075.4.1.7 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › SbmA_BacA | 0.72 | 61.0 | 3.70e-01 | 93.8% | 15.3% |
| 3937844 | 4207.1.1.1 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) › Med21 | 0.71 | 60.0 | 4.78e-01 | 92.2% | 52.8% |
| 3242228 | 192.5.1.0 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat | 0.70 | 58.0 | 4.72e-01 | 93.8% | 49.2% |
| 3630205 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.69 | 56.0 | 4.56e-01 | 89.1% | 48.3% |
| 3413723 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.69 | 61.0 | 5.15e-01 | 96.9% | 74.3% |
| 3553833 | 5086.1.1.102 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PTHB1_hp | 0.69 | 62.0 | 4.35e-01 | 98.4% | 75.8% |
| 3703409 | 4163.1.1.1 ↗ | alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 | 0.68 | 56.0 | 4.04e-01 | 92.2% | 32.2% |
| 3541873 | 3755.3.1.297 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF9 | 0.68 | 56.0 | 4.39e-01 | 93.8% | 72.1% |
| 3825046 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.67 | 54.0 | 4.26e-01 | 92.2% | 40.7% |
| 3488979 | 192.5.1.0 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat | 0.67 | 54.0 | 4.44e-01 | 93.8% | 47.2% |
| 3940232 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.66 | 54.0 | 4.66e-01 | 92.2% | 57.1% |
| 3755586 | 3291.1.1.118 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › KIF9 | 0.66 | 54.0 | 4.28e-01 | 93.8% | 72.9% |
| 3191661 | 3352.1.1.19 ↗ | alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › Mannosyl_trans2 | 0.66 | 56.0 | 3.42e-01 | 96.9% | 31.1% |
| 3290402 | 3567.1.1.86 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › DUF485 | 0.64 | 50.0 | 4.63e-01 | 89.1% | 68.2% |
| 5023516 | 3922.1.1.269 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Rad50_zn_hook | 0.64 | 53.0 | 3.70e-01 | 96.9% | 75.7% |
| 3646439 | 192.8.1.263 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › DUF7615 | 0.64 | 51.0 | 4.72e-01 | 92.2% | 69.4% |
| 3274959 | 2004.1.1.250 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd | 0.62 | 50.0 | 2.98e-01 | 93.8% | 11.1% |
| 3789558 | 192.15.1.3 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Vps23_core | 0.62 | 50.0 | 3.78e-01 | 93.8% | 35.4% |
| 3629550 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.60 | 51.0 | 3.19e-01 | 100.0% | 67.6% |
| 138580 | 150.5.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 | 0.59 | 47.0 | 4.23e-01 | 92.2% | 61.9% |
| 3924616 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.59 | 48.0 | 3.36e-01 | 93.8% | 26.0% |
D2
medium
residues 65-125
Domain cluster:
representative
CATH (32)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1t7sA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.81 | 64.0 | 4.96e-01 | 85.2% | 44.2% |
| 4l0rB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.79 | 61.0 | 5.79e-01 | 83.6% | 79.5% |
| 4abxA02 | 6.10.140.1090 | Special › Helix non-globular › Helix Hairpins › | 0.77 | 62.0 | 5.47e-01 | 86.9% | 62.1% |
| 2rkhA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.76 | 57.0 | 5.32e-01 | 80.3% | 67.1% |
| 3txsC01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.76 | 61.0 | 5.68e-01 | 86.9% | 72.0% |
| 1x4tA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.76 | 57.0 | 5.81e-01 | 80.3% | 91.4% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.75 | 65.0 | 4.47e-01 | 100.0% | 33.2% |
| 6lumD01 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.75 | 58.0 | 4.54e-01 | 86.9% | 40.8% |
| 2xzmO02 | 1.10.287.10 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding | 0.74 | 57.0 | 5.42e-01 | 82.0% | 72.9% |
| 4fvmA06 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.74 | 47.0 | 5.22e-01 | 78.7% | 83.3% |
| 4dloB02 | 1.25.40.610 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.74 | 51.0 | 4.11e-01 | 77.0% | 37.6% |
| 2f93B00 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.74 | 55.0 | 5.85e-01 | 82.0% | 100.0% |
| 1m5iA00 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.73 | 55.0 | 4.59e-01 | 80.3% | 48.6% |
| 4e6nA02 | 6.10.140.1010 | Special › Helix non-globular › Helix Hairpins › | 0.71 | 54.0 | 5.28e-01 | 82.0% | 77.3% |
| 2ip6A00 | 1.20.1440.140 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.70 | 46.0 | 4.10e-01 | 73.8% | 47.1% |
| 1ydxA02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.70 | 55.0 | 4.88e-01 | 86.9% | 63.3% |
| 3behB01 | 1.20.120.540 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels | 0.69 | 53.0 | 4.32e-01 | 85.2% | 43.6% |
| 2qtfA02 | 6.10.250.2860 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.69 | 47.0 | 5.07e-01 | 77.0% | 91.5% |
| 2mabA00 | 1.10.10.1350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain | 0.69 | 49.0 | 4.05e-01 | 78.7% | 42.2% |
| 2mtqA00 | 1.20.58.130 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 49.0 | 4.63e-01 | 77.0% | 65.8% |
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.68 | 53.0 | 4.97e-01 | 86.9% | 72.0% |
| 1tmxB00 | 2.60.130.10 | Mainly Beta › Sandwich › Protocatechuate 3,4-Dioxygenase, subunit A › Aromatic compound dioxygenase | 0.67 | 53.0 | 3.36e-01 | 100.0% | 18.1% |
| 2hepA00 | 1.10.287.540 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.66 | 44.0 | 4.94e-01 | 75.4% | 100.0% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.66 | 53.0 | 5.16e-01 | 88.5% | 86.6% |
| 4adnA01 | 1.20.1280.250 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.66 | 45.0 | 4.10e-01 | 72.1% | 52.9% |
| 3qf7A02 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.66 | 50.0 | 5.02e-01 | 90.2% | 82.5% |
| 3zgxA02 | 6.10.140.1720 | Special › Helix non-globular › Helix Hairpins › | 0.65 | 50.0 | 4.50e-01 | 86.9% | 59.3% |
| 4wr4A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.65 | 47.0 | 4.05e-01 | 80.3% | 46.7% |
| 1chuA03 | 1.20.58.100 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain | 0.64 | 50.0 | 4.57e-01 | 96.7% | 63.6% |
| 8igrI01 | 2.40.270.10 | Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 | 0.61 | 47.0 | 3.46e-01 | 90.2% | 29.5% |
| 3zq5A03 | 3.30.450.270 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PHY domain | 0.59 | 46.0 | 3.48e-01 | 86.9% | 85.6% |
| 2kjgA00 | 1.20.120.970 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.58 | 45.0 | 3.83e-01 | 83.6% | 75.8% |
ECOD (32)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3486248 | 6132.1.1.0 ↗ | alpha bundles › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain | 0.81 | 55.0 | 5.42e-01 | 77.0% | 66.2% |
| 5063166 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.81 | 63.0 | 5.22e-01 | 83.6% | 52.4% |
| 4129936 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.80 | 62.0 | 5.32e-01 | 83.6% | 56.8% |
| 5082509 | 101.1.2.31 ↗ | alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha | 0.79 | 56.0 | 4.36e-01 | 75.4% | 35.4% |
| 3170797 | 605.4.1.4 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › DUF202 | 0.79 | 72.0 | 5.65e-01 | 100.0% | 56.7% |
| 4323124 | 109.3.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 | 0.78 | 58.0 | 3.62e-01 | 80.3% | 16.1% |
| 3820045 | 603.1.1.118 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF7610 | 0.77 | 59.0 | 5.26e-01 | 82.0% | 58.8% |
| 3497645 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.77 | 60.0 | 5.48e-01 | 86.9% | 65.0% |
| 3491310 | 3826.1.1.67 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Med10 | 0.77 | 57.0 | 5.36e-01 | 80.3% | 72.0% |
| 3265419 | 1128.1.1.0 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein | 0.76 | 54.0 | 4.97e-01 | 90.2% | 57.5% |
| 3816625 | 605.3.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Nonstructural protein ns2, Nep, M1-binding domain › Nonstructural protein ns2, Nep, M1-binding domain | 0.76 | 55.0 | 5.16e-01 | 77.0% | 64.0% |
| 4665988 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.76 | 59.0 | 4.91e-01 | 83.6% | 52.4% |
| 3568826 | 5020.1.1.13 ↗ | extended segments › Subunit VIII of photosystem I reaction centre, PsaI › Subunit VIII of photosystem I reaction centre, PsaI › Subunit VIII of photosystem I reaction centre, PsaI › TMEM219 | 0.76 | 55.0 | 5.43e-01 | 77.0% | 87.7% |
| 3259629 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.76 | 61.0 | 5.20e-01 | 88.5% | 56.0% |
| 3801692 | 604.12.1.5 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › SUV3_C | 0.75 | 58.0 | 4.99e-01 | 83.6% | 61.1% |
| 3299130 | 6155.1.1.1 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv | 0.75 | 56.0 | 5.02e-01 | 80.3% | 57.6% |
| 3451778 | 376.1.1.8 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › U-box | 0.75 | 56.0 | 4.35e-01 | 86.9% | 36.3% |
| 3497466 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.75 | 56.0 | 4.92e-01 | 80.3% | 62.2% |
| 4666568 | 109.3.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 | 0.75 | 56.0 | 3.47e-01 | 82.0% | 14.3% |
| 3231463 | 632.8.1.2 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › Alpha-2-MRAP_C | 0.74 | 57.0 | 4.95e-01 | 83.6% | 54.7% |
| 3925075 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.74 | 52.0 | 5.02e-01 | 80.3% | 65.7% |
| 3595902 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.73 | 56.0 | 3.88e-01 | 83.6% | 25.5% |
| 3296047 | 6155.1.1.1 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv | 0.72 | 54.0 | 4.90e-01 | 82.0% | 58.8% |
| 3313934 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.72 | 55.0 | 4.79e-01 | 83.6% | 60.0% |
| 3954357 | 5076.2.1.13 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › DUF7847 | 0.72 | 59.0 | 3.84e-01 | 95.1% | 27.6% |
| 3574413 | 603.2.1.0 ↗ | alpha bundles › STAT-like › STAT › STAT | 0.71 | 50.0 | 4.40e-01 | 73.8% | 53.3% |
| 3884327 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.68 | 54.0 | 4.81e-01 | 88.5% | 67.8% |
| 5042382 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.68 | 58.0 | 5.17e-01 | 96.7% | 72.2% |
| 3189035 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.66 | 48.0 | 4.54e-01 | 80.3% | 82.7% |
| 4940435 | 2003.1.5.79 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23 | 0.63 | 57.0 | 3.65e-01 | 100.0% | 72.6% |
| 3654606 | 1128.1.1.1 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR | 0.60 | 41.0 | 3.95e-01 | 78.7% | 61.3% |
| 3625741 | 198.1.1.0 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like | 0.54 | 41.0 | 3.78e-01 | 100.0% | 61.1% |
D3
medium
residues 161-248
Domain cluster:
representative
CATH (63)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2ra1A01 | 1.20.58.790 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.77 | 54.0 | 5.25e-01 | 72.7% | 93.9% |
| 2fupA00 | 1.20.58.300 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like | 0.74 | 59.0 | 5.24e-01 | 86.4% | 99.2% |
| 2lsgA00 | 1.20.58.1280 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DNA repair protein Rev1, C-terminal domain | 0.72 | 62.0 | 6.06e-01 | 95.5% | 87.6% |
| 1fioA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 63.0 | 4.93e-01 | 98.9% | 98.9% |
| 3woyA00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.72 | 62.0 | 4.48e-01 | 95.5% | 34.1% |
| 1fpoC02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.71 | 51.0 | 5.05e-01 | 75.0% | 89.0% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 54.0 | 4.31e-01 | 81.8% | 72.8% |
| 1dceA01 | 1.25.40.120 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Protein prenylyltransferase | 0.70 | 58.0 | 3.95e-01 | 90.9% | 26.2% |
| 2d2sA01 | 1.20.58.1210 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain | 0.70 | 54.0 | 4.98e-01 | 84.1% | 77.6% |
| 3vwaA03 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.70 | 59.0 | 4.05e-01 | 98.9% | 27.2% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.70 | 50.0 | 4.76e-01 | 75.0% | 89.2% |
| 1dd5A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.69 | 48.0 | 4.49e-01 | 71.6% | 93.6% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.69 | 50.0 | 4.56e-01 | 76.1% | 81.2% |
| 2xl4A00 | 1.20.120.1420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › LntA helical domain | 0.68 | 53.0 | 4.40e-01 | 81.8% | 65.3% |
| 2ra1A03 | 1.20.58.770 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 47.0 | 5.24e-01 | 75.0% | 100.0% |
| 3nrxA00 | 1.20.58.1520 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 48.0 | 4.31e-01 | 73.9% | 73.2% |
| 2oduA02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 52.0 | 4.87e-01 | 80.7% | 85.7% |
| 2uubT00 | 1.20.58.110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 | 0.68 | 55.0 | 5.28e-01 | 87.5% | 81.8% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.67 | 47.0 | 4.42e-01 | 73.9% | 94.5% |
| 2d2sA02 | 1.20.58.1220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain | 0.66 | 60.0 | 5.72e-01 | 100.0% | 100.0% |
| 4jgwA01 | 1.20.870.10 | Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 | 0.66 | 53.0 | 4.45e-01 | 88.6% | 60.9% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.66 | 49.0 | 4.68e-01 | 79.5% | 89.6% |
| 3u3iA02 | 1.20.58.1110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 57.0 | 5.37e-01 | 96.6% | 89.8% |
| 3on4D00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.66 | 57.0 | 4.50e-01 | 96.6% | 61.6% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.66 | 48.0 | 4.96e-01 | 78.4% | 89.4% |
| 3edvB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 49.0 | 4.31e-01 | 81.8% | 75.0% |
| 5cwkA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.65 | 53.0 | 4.35e-01 | 94.3% | 47.6% |
| 7dswA01 | 1.20.1530.20 | Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › | 0.64 | 57.0 | 3.68e-01 | 100.0% | 39.0% |
| 1vctA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.63 | 51.0 | 4.72e-01 | 86.4% | 83.5% |
| 5bqnA02 | 1.20.1120.10 | Mainly Alpha › Up-down Bundle › "Clostridium botulinum neurotoxin B, ""coiled-coil"" domain" › "Clostridium botulinum neurotoxin b, ""coiled-coil"" domain" | 0.62 | 54.0 | 3.66e-01 | 100.0% | 88.9% |
| 2qvaA01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.62 | 53.0 | 4.73e-01 | 96.6% | 83.7% |
| 1e3pA02 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.62 | 43.0 | 4.44e-01 | 71.6% | 90.4% |
| 1txuA01 | 1.10.246.120 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.62 | 45.0 | 4.49e-01 | 79.5% | 84.0% |
| 8alzB08 | 1.10.3380.10 | Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain | 0.61 | 48.0 | 4.23e-01 | 84.1% | 96.2% |
| 2pfdA03 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.61 | 53.0 | 4.17e-01 | 100.0% | 84.2% |
| 2w3cA01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.61 | 51.0 | 3.70e-01 | 95.5% | 31.3% |
| 3pasA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 51.0 | 3.99e-01 | 92.0% | 54.7% |
| 3eabE00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.60 | 45.0 | 4.62e-01 | 80.7% | 96.5% |
| 3l1nA02 | 1.20.1280.140 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.60 | 44.0 | 4.42e-01 | 78.4% | 96.6% |
| 1yuzB01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.59 | 45.0 | 3.92e-01 | 81.8% | 97.8% |
| 3zsuA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.59 | 48.0 | 4.37e-01 | 88.6% | 65.3% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.59 | 43.0 | 4.10e-01 | 79.5% | 93.6% |
| 3fbzA01 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 40.0 | 3.91e-01 | 71.6% | 61.8% |
| 2vxxA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.59 | 42.0 | 3.45e-01 | 76.1% | 83.1% |
| 1dgfA03 | 1.20.1370.60 | Mainly Alpha › Up-down Bundle › Hemocyanin, N-terminal domain › | 0.58 | 49.0 | 4.54e-01 | 94.3% | 77.2% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.58 | 41.0 | 3.61e-01 | 72.7% | 55.7% |
| 2yevA03 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.58 | 43.0 | 3.45e-01 | 79.5% | 66.3% |
| 1s3qG00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.58 | 43.0 | 3.59e-01 | 79.5% | 98.2% |
| 3u8vA00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.57 | 42.0 | 4.30e-01 | 81.8% | 81.9% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.57 | 43.0 | 3.70e-01 | 81.8% | 96.0% |
| 1tjoB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.57 | 43.0 | 3.50e-01 | 81.8% | 81.7% |
| 2clbA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.57 | 40.0 | 3.38e-01 | 75.0% | 91.8% |
| 1qdbA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.56 | 38.0 | 3.28e-01 | 70.5% | 79.7% |
| 1sqgA01 | 1.10.940.10 | Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like | 0.55 | 44.0 | 3.81e-01 | 88.6% | 91.5% |
| 2oezA02 | 1.10.3900.10 | Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like | 0.55 | 43.0 | 3.54e-01 | 85.2% | 88.3% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.54 | 45.0 | 4.06e-01 | 92.0% | 87.7% |
| 3gyuA00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.54 | 43.0 | 3.20e-01 | 88.6% | 59.5% |
| 3frrA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.53 | 46.0 | 3.71e-01 | 100.0% | 73.1% |
| 1w07A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.53 | 47.0 | 3.84e-01 | 98.9% | 83.3% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.52 | 47.0 | 4.11e-01 | 100.0% | 70.7% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.52 | 42.0 | 3.66e-01 | 88.6% | 63.5% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.51 | 37.0 | 3.79e-01 | 98.9% | 77.6% |
| 6gpxB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 46.0 | 3.29e-01 | 100.0% | 52.5% |
ECOD (57)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3650927 | 109.4.1.170 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CLASP_N | 0.75 | 63.0 | 4.95e-01 | 96.6% | 45.1% |
| 3290471 | 601.1.1.61 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF8320 | 0.75 | 67.0 | 5.59e-01 | 100.0% | 65.8% |
| 3938085 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.75 | 67.0 | 4.34e-01 | 100.0% | 24.9% |
| 3494504 | 109.4.1.1965 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF28295 | 0.74 | 66.0 | 4.44e-01 | 100.0% | 31.3% |
| 5017746 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.74 | 65.0 | 5.08e-01 | 100.0% | 48.2% |
| 3917600 | 604.1.1.6 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_4 | 0.73 | 52.0 | 4.68e-01 | 73.9% | 80.0% |
| 3881581 | 310.2.1.11 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › DUF4456 | 0.73 | 54.0 | 4.34e-01 | 77.3% | 81.8% |
| 2818706 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.73 | 66.0 | 4.84e-01 | 100.0% | 45.7% |
| 3392844 | 109.4.1.933 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_Trm732 | 0.72 | 60.0 | 3.81e-01 | 90.9% | 19.0% |
| 5018410 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.72 | 64.0 | 4.86e-01 | 100.0% | 43.3% |
| 3834182 | 109.4.1.330 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BIG2_C | 0.72 | 64.0 | 4.08e-01 | 100.0% | 20.7% |
| 4033890 | 604.39.1.15 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › DUF2232 | 0.72 | 64.0 | 5.30e-01 | 98.9% | 56.1% |
| 5020411 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.72 | 51.0 | 4.31e-01 | 75.0% | 57.3% |
| 3623280 | 603.1.1.110 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF26585 | 0.71 | 58.0 | 4.52e-01 | 89.8% | 89.2% |
| 4968762 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.71 | 53.0 | 4.80e-01 | 77.3% | 79.1% |
| 3931763 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.71 | 60.0 | 5.46e-01 | 93.2% | 70.4% |
| 4015994 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.71 | 60.0 | 3.52e-01 | 94.3% | 14.1% |
| 5075584 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.70 | 59.0 | 4.78e-01 | 94.3% | 48.0% |
| 4032823 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.70 | 50.0 | 5.29e-01 | 75.0% | 91.3% |
| 5005528 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.70 | 53.0 | 5.12e-01 | 80.7% | 91.0% |
| 3276672 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.67 | 55.0 | 4.90e-01 | 90.9% | 98.5% |
| 3786750 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.67 | 49.0 | 4.68e-01 | 77.3% | 84.6% |
| 3764056 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.67 | 57.0 | 4.46e-01 | 95.5% | 47.7% |
| 3738337 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.66 | 49.0 | 4.61e-01 | 77.3% | 82.9% |
| 3557114 | 604.1.1.66 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_1st_PEPL | 0.66 | 51.0 | 4.75e-01 | 81.8% | 89.1% |
| 1206502 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.66 | 49.0 | 4.68e-01 | 79.5% | 89.6% |
| 5062478 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.66 | 47.0 | 4.68e-01 | 73.9% | 87.8% |
| 3716935 | 2485.1.1.0 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like | 0.66 | 53.0 | 3.58e-01 | 90.9% | 23.8% |
| 3262020 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.66 | 58.0 | 4.44e-01 | 98.9% | 47.3% |
| 4319172 | 604.39.1.15 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › DUF2232 | 0.66 | 57.0 | 4.01e-01 | 98.9% | 29.3% |
| 3920960 | 604.8.1.2 ↗ | alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo › Mitofilin | 0.66 | 49.0 | 4.29e-01 | 78.4% | 80.0% |
| 3892492 | 604.1.1.66 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_1st_PEPL | 0.66 | 50.0 | 4.63e-01 | 80.7% | 89.1% |
| 3304563 | 150.1.1.164 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › MENTAL | 0.65 | 47.0 | 3.76e-01 | 75.0% | 63.5% |
| 5049145 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.65 | 47.0 | 4.55e-01 | 77.3% | 92.9% |
| 3968183 | 3758.2.1.1 ↗ | alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB | 0.64 | 49.0 | 4.06e-01 | 83.0% | 82.3% |
| 3591222 | 604.1.1.198 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › BAG | 0.63 | 45.0 | 4.41e-01 | 75.0% | 91.6% |
| 3242717 | 188.1.1.1 ↗ | alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep | 0.62 | 51.0 | 3.61e-01 | 88.6% | 86.7% |
| 3276285 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.62 | 47.0 | 4.22e-01 | 81.8% | 88.0% |
| 4133287 | 1197.1.1.1 ↗ | alpha bundles › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › G3P_acyltransf | 0.61 | 49.0 | 3.93e-01 | 90.9% | 61.7% |
| 1701000 | 4950.1.1.1 ↗ | alpha complex topology › Botulinum neurotoxin A heavy chain › Botulinum neurotoxin A heavy chain › Botulinum neurotoxin A heavy chain › Toxin_trans | 0.60 | 51.0 | 3.43e-01 | 100.0% | 95.2% |
| 3235514 | 601.33.1.10 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › DUF19 | 0.58 | 41.0 | 4.49e-01 | 87.5% | 92.9% |
| 4592728 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.58 | 43.0 | 4.31e-01 | 79.5% | 94.4% |
| 4024515 | 5059.1.1.0 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter | 0.58 | 51.0 | 4.28e-01 | 100.0% | 74.8% |
| 3707107 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.58 | 51.0 | 3.44e-01 | 96.6% | 36.6% |
| 3936271 | 188.1.1.1 ↗ | alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep | 0.58 | 46.0 | 3.23e-01 | 87.5% | 80.0% |
| 4483437 | 601.13.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS › FliS | 0.58 | 41.0 | 3.70e-01 | 76.1% | 66.9% |
| 3457190 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.58 | 43.0 | 3.70e-01 | 80.7% | 51.7% |
| 3309583 | 604.12.1.65 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT_ATG1 | 0.57 | 42.0 | 4.32e-01 | 78.4% | 98.8% |
| 3591275 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 47.0 | 3.94e-01 | 95.5% | 75.2% |
| 4401833 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.56 | 41.0 | 4.01e-01 | 79.5% | 84.0% |
| 4988269 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.55 | 42.0 | 4.11e-01 | 81.8% | 76.8% |
| 3699244 | 601.24.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) › FRB_dom | 0.55 | 40.0 | 4.14e-01 | 80.7% | 82.4% |
| 3923736 | 551.1.1.1 ↗ | alpha arrays › Hsp90 co-chaperone CDC37 middle domain › Hsp90 co-chaperone CDC37 middle domain › Hsp90 co-chaperone CDC37 middle domain › CDC37_M | 0.54 | 44.0 | 3.84e-01 | 97.7% | 57.1% |
| 4873190 | 3291.1.1.3 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Ist1 | 0.53 | 46.0 | 3.69e-01 | 98.9% | 73.4% |
| 4950911 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.53 | 43.0 | 3.64e-01 | 86.4% | 52.4% |
| 3236728 | 106.1.1.0 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like | 0.52 | 44.0 | 3.72e-01 | 100.0% | 67.3% |
| 3209285 | 109.4.1.791 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_17 | 0.52 | 40.0 | 3.92e-01 | 94.3% | 77.9% |
D4
medium
residues 328-419
Domain cluster:
representative
CATH (26)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2fcwA00 | 1.20.81.10 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain | 0.80 | 55.0 | 5.22e-01 | 91.3% | 61.3% |
| 4nswB01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.79 | 71.0 | 5.12e-01 | 100.0% | 78.5% |
| 2ch7A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.78 | 63.0 | 4.24e-01 | 84.8% | 44.3% |
| 3qa8A04 | 1.20.1270.250 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.78 | 71.0 | 5.21e-01 | 100.0% | 85.4% |
| 4e40A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.76 | 68.0 | 4.97e-01 | 100.0% | 89.8% |
| 3buxB01 | 1.20.930.20 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain | 0.75 | 56.0 | 4.98e-01 | 78.3% | 69.0% |
| 3g67A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.75 | 59.0 | 4.45e-01 | 83.7% | 37.1% |
| 3ug9A02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.74 | 59.0 | 4.41e-01 | 85.9% | 72.0% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.72 | 50.0 | 4.45e-01 | 79.3% | 50.4% |
| 4heoA00 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.71 | 41.0 | 5.02e-01 | 71.7% | 96.4% |
| 4hkrA00 | 1.20.140.140 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Calcium release-activated calcium channel protein Orai | 0.67 | 53.0 | 4.39e-01 | 85.9% | 57.6% |
| 2zxqA06 | 1.20.1270.70 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle | 0.67 | 45.0 | 5.09e-01 | 73.9% | 97.0% |
| 2q7rB00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.66 | 58.0 | 5.01e-01 | 97.8% | 61.2% |
| 4btfA01 | 1.20.930.20 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain | 0.66 | 47.0 | 4.57e-01 | 73.9% | 77.0% |
| 2wsiA00 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.65 | 46.0 | 3.23e-01 | 72.8% | 84.9% |
| 2p18A00 | 3.60.15.10 | Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like | 0.65 | 47.0 | 3.32e-01 | 76.1% | 88.0% |
| 2debB02 | 3.30.559.10 | Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain | 0.64 | 46.0 | 3.20e-01 | 75.0% | 35.3% |
| 3jsbA01 | 1.20.1440.300 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › RNA-directed RNA polymerase L, helical domain | 0.63 | 41.0 | 4.35e-01 | 81.5% | 75.3% |
| 2k0nA00 | 1.10.246.20 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Coactivator CBP, KIX domain | 0.62 | 44.0 | 4.53e-01 | 72.8% | 84.7% |
| 3pm0A00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.62 | 49.0 | 3.14e-01 | 85.9% | 42.7% |
| 3akaA00 | 1.10.238.10 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand | 0.62 | 45.0 | 3.75e-01 | 77.2% | 63.0% |
| 5xfaA04 | 1.20.1440.230 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain | 0.61 | 41.0 | 4.26e-01 | 71.7% | 74.1% |
| 1jqkA03 | 1.20.1270.30 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.60 | 43.0 | 3.45e-01 | 75.0% | 45.1% |
| 7s0rB01 | 1.20.81.20 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › | 0.58 | 41.0 | 4.46e-01 | 73.9% | 89.5% |
| 1qh5A00 | 3.60.15.10 | Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like | 0.58 | 42.0 | 3.08e-01 | 77.2% | 88.5% |
| 2q58B00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.54 | 42.0 | 2.90e-01 | 82.6% | 40.1% |
ECOD (28)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4297121 | 3755.3.1.46 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › She9_MDM33 | 0.85 | 70.0 | 5.08e-01 | 84.8% | 41.8% |
| 3810801 | 632.22.1.139 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › KIF21A_4th | 0.85 | 66.0 | 5.49e-01 | 81.5% | 68.7% |
| 3517647 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.80 | 59.0 | 5.97e-01 | 76.1% | 93.3% |
| 3471712 | 604.8.1.0 ↗ | alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo | 0.76 | 57.0 | 5.11e-01 | 78.3% | 57.6% |
| 4600200 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.75 | 56.0 | 5.20e-01 | 78.3% | 100.0% |
| 3941235 | 4992.1.1.0 ↗ | extended segments › RelB-like › RelB-like › RelB-like | 0.75 | 58.0 | 5.82e-01 | 83.7% | 82.1% |
| 3517579 | 6004.1.1.2 ↗ | extended segments › FATC domain › FATC domain › FATC domain › ETC_C1_NDUFA5 | 0.75 | 51.0 | 5.44e-01 | 70.7% | 95.0% |
| 4488596 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.74 | 57.0 | 5.26e-01 | 80.4% | 100.0% |
| 3350129 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.73 | 57.0 | 4.25e-01 | 81.5% | 77.1% |
| 3469354 | 6004.1.1.2 ↗ | extended segments › FATC domain › FATC domain › FATC domain › ETC_C1_NDUFA5 | 0.73 | 52.0 | 4.80e-01 | 73.9% | 68.7% |
| 4988178 | 633.29.1.0 ↗ | alpha bundles › Bromodomain-like › Putative uncharacterized protein PAV1-137 › Putative uncharacterized protein PAV1-137 | 0.72 | 52.0 | 5.19e-01 | 76.1% | 80.0% |
| 2755028 | 6004.1.1.2 ↗ | extended segments › FATC domain › FATC domain › FATC domain › ETC_C1_NDUFA5 | 0.72 | 51.0 | 4.73e-01 | 73.9% | 69.6% |
| 2983210 | 6004.1.1.2 ↗ | extended segments › FATC domain › FATC domain › FATC domain › ETC_C1_NDUFA5 | 0.71 | 50.0 | 4.61e-01 | 73.9% | 67.8% |
| 4823831 | 6004.1.1.2 ↗ | extended segments › FATC domain › FATC domain › FATC domain › ETC_C1_NDUFA5 | 0.69 | 49.0 | 4.69e-01 | 73.9% | 73.1% |
| 3257678 | 5000.4.1.0 ↗ | alpha arrays › Toxins' membrane translocation domains › delta-Endotoxin (insectocide), N-terminal domain › delta-Endotoxin (insectocide), N-terminal domain | 0.69 | 63.0 | 4.43e-01 | 98.9% | 35.3% |
| 4809777 | 6004.1.1.2 ↗ | extended segments › FATC domain › FATC domain › FATC domain › ETC_C1_NDUFA5 | 0.69 | 49.0 | 4.62e-01 | 73.9% | 68.8% |
| 4034211 | 632.19.1.3 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A › DUF1542 | 0.68 | 55.0 | 4.98e-01 | 88.0% | 73.6% |
| 4012137 | 611.7.1.0 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain | 0.68 | 52.0 | 4.62e-01 | 82.6% | 65.2% |
| 4854386 | 6004.1.1.2 ↗ | extended segments › FATC domain › FATC domain › FATC domain › ETC_C1_NDUFA5 | 0.68 | 52.0 | 5.08e-01 | 81.5% | 83.3% |
| 3459041 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.68 | 46.0 | 4.91e-01 | 70.7% | 91.3% |
| 4939616 | 633.12.1.0 ↗ | alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like | 0.67 | 50.0 | 5.20e-01 | 77.2% | 83.5% |
| 3618557 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.67 | 46.0 | 4.69e-01 | 70.7% | 87.8% |
| 3724953 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.67 | 51.0 | 4.36e-01 | 82.6% | 66.5% |
| 3726746 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.66 | 52.0 | 4.48e-01 | 85.9% | 71.7% |
| 4533356 | 1128.1.1.2 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR_2 | 0.65 | 47.0 | 4.96e-01 | 75.0% | 100.0% |
| 3969653 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.55 | 44.0 | 4.65e-01 | 87.0% | 97.5% |
| 3974456 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.54 | 37.0 | 4.06e-01 | 72.8% | 86.7% |
| 3951393 | 191.1.1.8 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_33 | 0.52 | 41.0 | 3.55e-01 | 83.7% | 87.9% |