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ON970615.1__UVK63420.1__SEA_BAUDELAIRE_35__00035

Bact-Vir

ON970615.1__UVK63420.1__SEA_BAUDELAIRE_35__00035

Identity

Accession:
ON970615 ↗
Kingdom:
phage

Quality

87.3 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-72
PDB
Domain cluster: representative
CATH (66)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1xg2B00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.93 68.0 5.17e-01 83.3% 36.4%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.90 60.0 5.95e-01 76.4% 66.2%
1qv9A02 6.10.140.120 Special › Helix non-globular › Helix Hairpins › 0.90 64.0 5.54e-01 79.2% 51.5%
3qo8A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.89 74.0 6.39e-01 87.5% 67.9%
3tklB01 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.89 62.0 6.72e-01 79.2% 83.9%
4ceiA03 6.10.250.2380 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.88 66.0 5.57e-01 77.8% 96.4%
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.88 78.0 5.40e-01 94.4% 32.4%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.88 68.0 6.24e-01 90.3% 64.1%
1skvA00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.87 63.0 6.63e-01 80.6% 84.4%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.87 73.0 6.24e-01 94.4% 59.8%
4nb5B02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.86 61.0 6.46e-01 77.8% 82.8%
2pmsC00 6.10.140.920 Special › Helix non-globular › Helix Hairpins › 0.86 72.0 6.17e-01 93.1% 58.7%
1rq0A01 6.10.140.160 Special › Helix non-globular › Helix Hairpins › 0.86 70.0 6.66e-01 87.5% 74.7%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.86 75.0 4.80e-01 94.4% 22.3%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.85 69.0 5.00e-01 88.9% 33.3%
4hkaA01 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.85 67.0 4.34e-01 83.3% 21.4%
3d36B02 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.85 58.0 6.32e-01 80.6% 83.6%
3kavA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.85 59.0 5.19e-01 79.2% 51.0%
3hr0B01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.84 69.0 6.74e-01 88.9% 81.0%
3kr9A02 1.10.287.1890 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.84 54.0 5.80e-01 70.8% 77.0%
1yg2A02 6.10.140.190 Special › Helix non-globular › Helix Hairpins › 0.84 67.0 6.16e-01 84.7% 70.0%
4aifA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.82 54.0 4.23e-01 75.0% 34.0%
1t7sA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.81 69.0 5.62e-01 91.7% 57.4%
1gaxA05 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.80 64.0 6.38e-01 95.8% 83.6%
2gl2B00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.80 69.0 5.96e-01 94.4% 89.0%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.79 68.0 4.53e-01 93.1% 26.0%
1wpaA01 6.10.140.340 Special › Helix non-globular › Helix Hairpins › 0.79 62.0 5.53e-01 83.3% 87.9%
2ficB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.78 67.0 4.77e-01 93.1% 34.3%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.78 69.0 5.33e-01 98.6% 77.0%
5b1oA00 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.78 63.0 6.62e-01 91.7% 96.9%
3pt1A02 1.20.930.60 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › 0.78 55.0 4.66e-01 75.0% 76.7%
3nbxX03 1.20.58.1510 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 54.0 4.81e-01 90.3% 52.5%
1cunA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 61.0 5.43e-01 97.2% 61.8%
2l1lB00 1.20.1440.250 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.76 49.0 4.00e-01 72.2% 37.0%
1wp7A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.76 55.0 5.78e-01 77.8% 89.1%
3layF00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.75 55.0 5.37e-01 77.8% 70.5%
1u5pA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 59.0 5.25e-01 97.2% 58.3%
2mtqA00 1.20.58.130 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 49.0 4.96e-01 70.8% 67.1%
4e6nA02 6.10.140.1010 Special › Helix non-globular › Helix Hairpins › 0.75 58.0 6.10e-01 83.3% 95.5%
3uumA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 62.0 5.19e-01 97.2% 54.1%
1m62A00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.74 50.0 4.76e-01 70.8% 63.2%
1urfA00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.74 58.0 5.63e-01 84.7% 76.5%
3cazB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.74 62.0 4.41e-01 93.1% 42.9%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.73 51.0 4.30e-01 76.4% 44.1%
1rx0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.73 63.0 4.86e-01 94.4% 61.9%
5iduC03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.72 62.0 4.77e-01 94.4% 59.7%
3pe0A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 60.0 5.19e-01 88.9% 62.3%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.72 50.0 4.78e-01 75.0% 62.4%
4lunU00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.71 64.0 4.17e-01 100.0% 43.4%
3gnlB02 1.10.287.1890 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.71 49.0 5.03e-01 79.2% 76.5%
2jaeA03 1.20.1440.240 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.70 48.0 4.29e-01 70.8% 57.4%
2cazD00 6.10.140.820 Special › Helix non-globular › Helix Hairpins › 0.70 48.0 5.16e-01 72.2% 88.3%
2yf4F00 1.10.3420.10 Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain 0.70 54.0 4.33e-01 83.3% 42.0%
6lumD01 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.69 52.0 4.30e-01 81.9% 45.6%
2np9A01 1.20.58.1300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 46.0 3.78e-01 76.4% 37.3%
6xxvC00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.68 57.0 4.96e-01 95.8% 59.5%
4l8iB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.68 59.0 5.06e-01 98.6% 60.7%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 51.0 4.04e-01 81.9% 72.1%
3axjB01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.68 56.0 4.40e-01 93.1% 45.2%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.68 59.0 5.12e-01 95.8% 63.3%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 53.0 4.57e-01 88.9% 53.3%
6vudA01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.66 58.0 5.05e-01 95.8% 63.3%
7zxkC01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.62 46.0 3.59e-01 79.2% 65.3%
4wqoD00 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.59 50.0 3.98e-01 93.1% 87.9%
2yqyA00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.58 41.0 3.44e-01 75.0% 89.7%
3craA02 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.56 43.0 3.50e-01 80.6% 76.6%
ECOD (73)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3471712 604.8.1.0 alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo 0.92 70.0 5.67e-01 79.2% 60.0%
3482892 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.92 70.0 4.43e-01 84.7% 18.7%
3248119 109.4.1.1207 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_TmcB 0.90 77.0 6.19e-01 88.9% 51.2%
3711643 3939.1.1.0 alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain 0.90 80.0 5.24e-01 94.4% 60.4%
4649114 3559.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Med22 0.90 66.0 5.79e-01 76.4% 55.0%
3491738 632.8.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 0.89 72.0 6.35e-01 88.9% 61.6%
3485540 603.1.1.1 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin 0.89 71.0 5.14e-01 93.1% 34.3%
3600361 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.88 70.0 6.28e-01 83.3% 66.3%
3944731 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.88 77.0 5.78e-01 94.4% 46.1%
3959288 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.88 78.0 7.74e-01 97.2% 89.3%
5018716 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.88 67.0 6.86e-01 79.2% 81.4%
4315478 150.8.1.5 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE › EspA_EspE 0.88 75.0 5.30e-01 94.4% 34.6%
3284507 150.8.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE 0.88 79.0 5.67e-01 100.0% 37.3%
5075952 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.87 65.0 5.23e-01 83.3% 43.8%
3942662 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.85 72.0 6.43e-01 95.8% 67.4%
3235820 604.26.1.0 alpha bundles › Spectrin repeat-like › Bag6-BAG › Bag6-BAG 0.85 72.0 5.26e-01 94.4% 36.7%
3387205 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.84 63.0 5.84e-01 79.2% 77.8%
5067572 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.84 63.0 5.43e-01 88.9% 53.3%
3737161 3559.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Med22 0.84 69.0 5.95e-01 88.9% 58.2%
4336172 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.84 70.0 4.39e-01 93.1% 19.4%
3730423 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.84 73.0 4.63e-01 93.1% 21.3%
3493417 4163.1.1.1 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 0.84 70.0 5.27e-01 88.9% 40.6%
3953795 150.8.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE 0.83 77.0 5.69e-01 100.0% 42.4%
3506760 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.83 69.0 5.56e-01 88.9% 50.8%
3413774 632.15.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) 0.83 68.0 5.71e-01 93.1% 54.8%
3962942 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.82 76.0 5.88e-01 100.0% 48.0%
3386594 3291.1.1.197 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › MCPsignal 0.82 75.0 6.58e-01 100.0% 81.9%
3962324 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.82 75.0 5.22e-01 100.0% 34.5%
3795757 603.1.1.97 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE 0.82 73.0 4.82e-01 95.8% 45.7%
3262164 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.82 69.0 4.62e-01 97.2% 25.4%
3740232 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.82 59.0 4.71e-01 76.4% 43.6%
3563618 73.1.1.0 beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain 0.81 67.0 5.76e-01 90.3% 58.2%
3779360 192.5.1.0 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat 0.81 61.0 4.67e-01 84.7% 36.3%
3195418 192.8.1.376 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › RRP36 0.81 74.0 6.68e-01 100.0% 80.0%
3242447 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.80 67.0 5.87e-01 97.2% 61.9%
3615471 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.80 66.0 5.65e-01 93.1% 58.2%
3990182 3922.1.1.226 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Fy-3 0.79 68.0 5.71e-01 93.1% 57.4%
3894879 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.78 58.0 5.05e-01 79.2% 53.3%
3778716 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.78 62.0 5.51e-01 97.2% 60.0%
4042824 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.78 62.0 5.97e-01 97.2% 76.2%
3912386 150.3.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Hormone_1 0.77 56.0 3.98e-01 76.4% 26.8%
3773859 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.77 61.0 5.43e-01 97.2% 60.0%
3955729 150.8.1.7 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE › PF29644 0.77 70.0 5.28e-01 100.0% 43.6%
4096596 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.76 64.0 3.82e-01 88.9% 14.1%
5043437 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.76 61.0 5.35e-01 86.1% 59.0%
3224632 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.76 61.0 5.38e-01 97.2% 60.0%
3489764 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.76 62.0 5.47e-01 97.2% 61.0%
5036846 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.76 57.0 4.51e-01 83.3% 40.0%
4408647 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.75 61.0 5.36e-01 87.5% 60.0%
3789322 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.75 62.0 4.16e-01 93.1% 23.9%
1144608 310.2.1.1 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF 0.74 64.0 5.39e-01 97.2% 58.8%
3545240 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.74 60.0 5.24e-01 95.8% 58.3%
3628421 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.74 58.0 4.72e-01 88.9% 45.0%
3895658 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.73 61.0 5.32e-01 97.2% 60.0%
3249236 4207.1.2.93 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region › RNA12 0.73 67.0 4.67e-01 100.0% 55.5%
3474685 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.73 59.0 5.07e-01 97.2% 55.7%
3404881 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.72 54.0 4.31e-01 79.2% 90.0%
3876659 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.72 57.0 3.95e-01 97.2% 25.3%
3860575 150.3.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Hormone_1 0.71 58.0 4.19e-01 90.3% 90.6%
3212004 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.71 55.0 4.18e-01 83.3% 35.3%
3400732 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.71 57.0 4.89e-01 97.2% 54.2%
3396370 192.15.1.2 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Mod_r 0.70 53.0 4.08e-01 80.6% 36.9%
3573876 109.4.1.228 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo84_C 0.70 63.0 4.21e-01 95.8% 39.6%
3330287 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.70 57.0 4.68e-01 90.3% 51.1%
4000037 192.15.1.0 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.70 48.0 5.11e-01 72.2% 86.7%
2625677 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.68 57.0 4.96e-01 95.8% 59.5%
3742303 310.2.1.1 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF 0.68 62.0 4.47e-01 98.6% 57.7%
4596972 150.3.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine 0.68 59.0 4.27e-01 94.4% 93.8%
3903553 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.68 59.0 5.12e-01 100.0% 65.2%
3619654 192.15.1.2 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Mod_r 0.66 53.0 4.11e-01 93.1% 40.6%
4453591 3602.1.1.4 alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › RRP36 0.63 57.0 4.55e-01 97.2% 61.5%
3749996 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.62 49.0 4.17e-01 95.8% 51.2%
3398025 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.61 47.0 4.30e-01 97.2% 62.0%
D2 medium residues 73-169
PDB
Domain cluster: representative
CATH (69)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4lwsB00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.83 64.0 6.69e-01 96.9% 88.6%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.81 70.0 6.93e-01 100.0% 87.3%
2c5iT00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.80 53.0 5.40e-01 100.0% 69.1%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.80 61.0 6.70e-01 90.7% 100.0%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 58.0 5.26e-01 95.9% 59.4%
2wyhB04 1.20.1270.50 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain 0.77 53.0 5.30e-01 99.0% 68.3%
1zkeA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 60.0 6.48e-01 96.9% 97.5%
1fs0G02 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.76 66.0 6.95e-01 91.8% 100.0%
1b48A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.75 46.0 4.41e-01 95.9% 54.1%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.75 59.0 6.28e-01 100.0% 98.8%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.75 54.0 5.21e-01 87.6% 67.3%
4dylA02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.75 64.0 6.50e-01 97.9% 94.7%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.74 67.0 5.58e-01 100.0% 59.0%
1lvfB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 53.0 5.24e-01 83.5% 70.2%
3u0cA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.74 68.0 5.80e-01 100.0% 67.5%
6p73A02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.72 53.0 4.67e-01 86.6% 52.4%
3qweA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.72 65.0 4.67e-01 100.0% 36.2%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.71 48.0 4.94e-01 78.4% 72.5%
4g1tA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.71 32.0 2.97e-01 100.0% 32.5%
6q45G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.71 65.0 5.63e-01 100.0% 69.2%
3aeiA00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.71 60.0 6.11e-01 90.7% 100.0%
3thxB04 1.10.1420.10 Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › 0.70 62.0 5.65e-01 96.9% 85.2%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.70 45.0 4.66e-01 80.4% 68.8%
3uumA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 60.0 5.54e-01 95.9% 73.8%
4jioA02 1.20.140.50 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › alix/aip1 like domains 0.70 64.0 5.56e-01 100.0% 69.2%
4nqiD00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.69 64.0 4.77e-01 100.0% 68.1%
3ck6C02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.69 53.0 4.92e-01 99.0% 65.5%
1e1dA02 1.20.1270.20 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.69 42.0 4.49e-01 97.9% 70.2%
2ozbB01 1.10.287.4070 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.69 59.0 5.38e-01 94.8% 100.0%
2g38B00 1.20.1260.20 Mainly Alpha › Up-down Bundle › Ferritin › PPE superfamily 0.69 61.0 4.98e-01 100.0% 53.8%
1x04A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.69 60.0 4.76e-01 100.0% 47.0%
5y06A01 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.69 63.0 4.71e-01 100.0% 66.8%
2nnwA02 1.10.287.4070 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.68 62.0 5.67e-01 100.0% 99.2%
6iknD01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.68 63.0 4.49e-01 100.0% 68.5%
3ggyA00 1.20.1260.60 Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 0.68 53.0 4.29e-01 92.8% 43.5%
4mndA02 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.68 41.0 3.24e-01 92.8% 29.8%
1ewqA04 1.10.1420.10 Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › 0.68 61.0 5.45e-01 100.0% 91.9%
5yk4A04 1.10.1420.10 Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › 0.67 59.0 5.34e-01 100.0% 92.6%
4lwsA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.66 59.0 5.88e-01 95.9% 95.0%
2dnxA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 52.0 4.73e-01 97.9% 63.1%
1fxkB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.66 59.0 5.74e-01 100.0% 91.7%
2vs0A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.66 49.0 5.23e-01 100.0% 95.1%
1bdp002 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.65 57.0 5.52e-01 95.9% 95.4%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.65 58.0 4.73e-01 100.0% 52.5%
3v5uA01 6.10.280.80 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region 0.65 47.0 5.19e-01 90.7% 98.7%
4wjg400 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.65 59.0 4.29e-01 100.0% 39.1%
3vbbE01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.65 57.0 5.32e-01 95.9% 82.4%
2rd0B00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.65 59.0 5.19e-01 100.0% 81.3%
6zhiB02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.65 39.0 4.16e-01 89.7% 68.7%
3spcA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 58.0 5.33e-01 100.0% 86.6%
6l3tA01 1.20.1440.80 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Gap junction channel protein cysteine-rich domain 0.64 57.0 4.53e-01 99.0% 92.5%
8b70A01 1.20.1740.10 Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I 0.64 54.0 3.54e-01 92.8% 81.1%
1f1mA00 1.20.120.240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 0.64 56.0 4.73e-01 96.9% 100.0%
3ofnY00 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.64 56.0 5.37e-01 99.0% 89.6%
4dxwA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 57.0 5.46e-01 99.0% 90.2%
1dn1B00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 57.0 4.31e-01 97.9% 56.8%
1f6fA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.62 48.0 3.88e-01 81.4% 60.7%
1wleA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.62 54.0 5.13e-01 95.9% 85.1%
2qe7G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.62 53.0 5.35e-01 99.0% 94.8%
1l8dA00 1.10.287.510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.61 54.0 5.36e-01 100.0% 97.1%
2fji101 1.10.357.50 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.61 50.0 3.84e-01 86.6% 81.3%
1wpaA01 6.10.140.340 Special › Helix non-globular › Helix Hairpins › 0.60 53.0 5.30e-01 97.9% 94.9%
4xvxA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.60 49.0 4.27e-01 88.7% 93.2%
3anwA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 49.0 4.66e-01 88.7% 77.9%
3hm6X01 1.10.506.10 Mainly Alpha › Orthogonal Bundle › GTPase Activation - p120GAP; domain 1 › GTPase Activation - p120gap; domain 1 0.58 48.0 3.23e-01 90.7% 49.4%
6whpA01 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.58 50.0 3.68e-01 97.9% 68.6%
1dxrL02 1.20.85.10 Mainly Alpha › Up-down Bundle › Photosynthetic Reaction Center, subunit M; domain 1 › Photosystem II protein D1-like 0.57 48.0 4.62e-01 100.0% 81.5%
7fh5A01 2.60.120.330 Mainly Beta › Sandwich › Jelly Rolls › B-lactam Antibiotic, Isopenicillin N Synthase; Chain 0.56 50.0 3.66e-01 97.9% 46.2%
1ux5A03 1.20.58.2220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Formin, FH2 domain 0.56 48.0 3.70e-01 99.0% 61.1%
ECOD (64)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3955729 150.8.1.7 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE › PF29644 0.86 79.0 6.46e-01 97.9% 57.0%
3954913 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.84 76.0 7.18e-01 100.0% 82.6%
5020161 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.78 72.0 5.99e-01 100.0% 100.0%
4956930 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.78 73.0 5.31e-01 100.0% 41.7%
4623929 304.58.1.0 a+b two layers › Alpha-beta plaits › FepE-like › FepE-like 0.77 70.0 5.09e-01 100.0% 39.2%
4203130 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.76 69.0 6.45e-01 100.0% 80.9%
3586442 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.76 55.0 5.33e-01 86.6% 67.3%
4349607 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.75 60.0 5.81e-01 95.9% 75.5%
4957738 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.75 69.0 5.76e-01 99.0% 73.1%
4025029 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.75 68.0 6.06e-01 96.9% 88.5%
3797517 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.74 69.0 4.81e-01 100.0% 45.0%
3485296 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.73 66.0 6.42e-01 95.9% 96.2%
3415933 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.73 68.0 5.80e-01 100.0% 74.7%
3713589 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.73 65.0 6.00e-01 100.0% 76.7%
4954786 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.73 57.0 6.09e-01 100.0% 95.3%
3277724 150.5.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.73 66.0 6.75e-01 100.0% 100.0%
3202986 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.73 67.0 6.13e-01 100.0% 85.6%
4055098 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.72 67.0 6.13e-01 100.0% 89.6%
4984546 3447.1.1.4 alpha bundles › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) › PEMT 0.72 51.0 4.37e-01 72.2% 89.7%
3704047 5.1.4.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.72 63.0 3.93e-01 93.8% 20.2%
3499836 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.71 61.0 5.21e-01 100.0% 58.1%
3638435 1073.1.1.14 alpha arrays › Mitochondrial calcium uniporter (MCU) › Mitochondrial calcium uniporter (MCU) › Mitochondrial calcium uniporter (MCU) › LMBR1 0.71 63.0 5.98e-01 95.9% 90.4%
3278767 2004.1.1.567 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23 0.71 65.0 3.87e-01 100.0% 23.7%
3595979 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.71 59.0 6.04e-01 97.9% 90.5%
3712081 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.71 62.0 6.00e-01 95.9% 91.8%
3635376 3755.3.1.298 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › ING 0.70 65.0 5.75e-01 100.0% 74.8%
4672193 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.70 61.0 5.53e-01 95.9% 70.0%
4988993 5086.1.1.231 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Rad50_zn_hook 0.70 64.0 5.50e-01 100.0% 78.0%
3616265 3922.1.1.279 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › PF30391 0.70 60.0 5.59e-01 93.8% 75.0%
3406351 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.70 64.0 6.15e-01 100.0% 98.2%
3717340 605.1.1.155 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Gpi1 0.70 60.0 4.71e-01 93.8% 56.5%
3445440 3755.4.1.17 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Rx_N 0.70 61.0 5.22e-01 97.9% 60.7%
3517171 604.8.1.3 alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo › Gpi1 0.69 61.0 4.75e-01 96.9% 55.2%
4995244 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.69 61.0 5.91e-01 96.9% 97.3%
5054860 3755.3.1.305 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Rad50_zn_hook 0.69 63.0 5.08e-01 100.0% 57.3%
3988581 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.69 60.0 6.28e-01 95.9% 100.0%
4950238 192.5.1.39 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › DUF4405 0.69 51.0 5.37e-01 91.8% 87.1%
4931058 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.69 63.0 5.16e-01 100.0% 94.7%
4978597 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.68 57.0 4.54e-01 100.0% 46.5%
3764851 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.68 55.0 5.75e-01 94.8% 94.4%
3544014 633.23.1.40 alpha bundles › Bromodomain-like › Claudin › Claudin › TM225 0.68 56.0 4.66e-01 89.7% 99.4%
3961947 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.68 61.0 5.24e-01 100.0% 70.3%
4015122 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.68 62.0 5.60e-01 100.0% 76.9%
3347723 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.67 52.0 4.65e-01 81.4% 94.1%
5028061 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.67 57.0 5.87e-01 91.8% 100.0%
3758701 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.67 60.0 6.12e-01 97.9% 100.0%
3887481 192.13.1.0 alpha bundles › Long alpha-hairpin › ISY1 N-terminal domain-like › ISY1 N-terminal domain-like 0.66 50.0 4.91e-01 96.9% 73.3%
60305 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.66 59.0 5.79e-01 100.0% 94.3%
3828336 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.65 59.0 5.59e-01 100.0% 87.7%
5035493 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.65 59.0 5.75e-01 100.0% 95.2%
3623411 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.65 58.0 5.88e-01 100.0% 100.0%
4271212 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.65 58.0 5.41e-01 100.0% 81.3%
3274487 605.1.1.155 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Gpi1 0.64 57.0 4.68e-01 97.9% 62.3%
5071781 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.64 58.0 4.75e-01 100.0% 94.9%
3504822 6170.1.1.0 alpha bundles › Kv7 proximal C-terminal Domain › Kv7 proximal C-terminal Domain › Kv7 proximal C-terminal Domain 0.64 50.0 5.52e-01 83.5% 100.0%
3499150 3954.1.1.1 alpha arrays › Phosphodiesterase 4 upstream conserved regions (UCR) › Phosphodiesterase 4 upstream conserved regions (UCR) › Phosphodiesterase 4 upstream conserved regions (UCR) › PDE4_UCR 0.64 50.0 4.59e-01 83.5% 67.2%
3715029 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.63 55.0 3.76e-01 94.8% 27.9%
3646869 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.63 51.0 3.49e-01 87.6% 64.4%
4451459 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.62 54.0 4.97e-01 95.9% 75.2%
3428908 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 53.0 3.20e-01 100.0% 15.0%
3202208 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.59 46.0 4.01e-01 90.7% 54.0%
4021717 604.6.1.15 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › Helo_like_N 0.59 52.0 4.50e-01 99.0% 64.5%
4985682 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.57 43.0 3.78e-01 77.3% 60.0%
4593130 601.7.1.40 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › Cas13a_C 0.54 47.0 3.27e-01 97.9% 31.5%
D3 medium residues 170-313
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF23275.2 best TPR_23 97.7 1.30e-27 77.1% 43.6%
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3k3oA02 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 34.0 4.11e-01 70.1% 96.4%
4xaxB02 1.20.58.1290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain 0.56 34.0 3.98e-01 86.8% 87.9%
7ldgA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.54 46.0 4.05e-01 94.4% 68.2%
4mmhA01 1.50.10.100 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase 0.53 47.0 3.56e-01 99.3% 52.2%
2b6cA01 1.20.1660.10 Mainly Alpha › Up-down Bundle › ARM repeat fold › Hypothetical protein (EF3068) 0.53 32.0 3.46e-01 89.6% 71.6%
6d5xA00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.52 40.0 4.00e-01 80.6% 76.2%
4qhpA05 1.25.50.10 Mainly Alpha › Alpha Horseshoe › Zincin-like fold › Peptidase M1, alanyl aminopeptidase, C-terminal domain 0.52 47.0 3.65e-01 100.0% 65.1%
4iluA02 1.20.58.1290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain 0.52 34.0 3.78e-01 86.8% 85.6%
7ep1B01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.52 44.0 3.75e-01 93.8% 61.2%
3rc3A05 1.20.58.1080 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 37.0 4.08e-01 75.7% 94.7%
3anwB00 1.20.58.2050 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.50 38.0 3.72e-01 80.6% 84.6%
4me9B00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.50 39.0 3.59e-01 81.9% 100.0%
ECOD (11)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3280675 109.4.1.2062 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_23 0.82 77.0 5.14e-01 99.3% 31.7%
3724862 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.62 35.0 3.42e-01 89.6% 49.0%
3915138 109.4.1.901 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_GCN1 0.61 42.0 2.80e-01 91.0% 16.9%
None 0.59 45.0 3.91e-01 90.3% 52.3%
3467405 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 42.0 4.33e-01 88.9% 83.6%
3191797 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 46.0 4.25e-01 93.1% 86.3%
3917586 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 42.0 4.28e-01 97.9% 87.9%
3676569 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 44.0 4.49e-01 95.1% 100.0%
3937272 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 39.0 4.11e-01 94.4% 89.2%
3853257 3736.1.1.1 alpha superhelices › NLRC4 helical domain HD2 › NLRC4 helical domain HD2 › NLRC4 helical domain HD2 › NLRC4_HD2 0.51 39.0 4.19e-01 91.7% 95.8%
3471868 6171.1.1.1 alpha bundles › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases › JHD 0.51 38.0 4.16e-01 80.6% 99.1%
D4 medium residues 314-393
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF23275.2 best TPR_23 49.2 9.00e-13 100.0% 31.6%
CATH (34)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1wrdA00 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 60.0 5.70e-01 100.0% 85.7%
4rngC00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.66 56.0 5.60e-01 100.0% 92.8%
1n4kA02 1.25.10.30 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › IP3 receptor type 1 binding core, RIH domain 0.66 59.0 4.81e-01 100.0% 56.8%
4c91A03 1.20.58.2150 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 56.0 4.41e-01 100.0% 56.4%
1y1uA01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.64 54.0 4.17e-01 96.2% 79.5%
4j05A00 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.64 49.0 3.07e-01 83.7% 15.4%
3purA03 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 54.0 4.92e-01 100.0% 79.1%
5nl6A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 54.0 4.95e-01 100.0% 86.1%
1eguA02 1.50.10.100 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase 0.61 52.0 3.47e-01 100.0% 21.8%
2i0mA02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.60 51.0 4.80e-01 97.5% 84.2%
3k3oA02 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 53.0 5.22e-01 100.0% 92.9%
3r2qA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 51.0 4.68e-01 100.0% 77.9%
2d9dA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.60 48.0 4.71e-01 100.0% 82.0%
3vkgB03 1.20.58.1120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dynein motor heavy chain, linker domain, subdomain 4 0.60 52.0 4.25e-01 100.0% 55.1%
6lkzC01 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.59 43.0 2.81e-01 77.5% 92.6%
1cnt200 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.59 41.0 3.50e-01 71.2% 100.0%
2w02B01 1.10.150.640 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › AcsD, thumb domain, helical bundle 0.58 34.0 3.56e-01 98.8% 62.2%
3ebbA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.58 50.0 3.49e-01 96.2% 44.3%
1xfiA02 1.20.1700.10 Mainly Alpha › Up-down Bundle › AF1104-like › AF1104-like 0.58 39.0 3.78e-01 72.5% 62.2%
5xfaA04 1.20.1440.230 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain 0.57 44.0 4.35e-01 96.2% 78.8%
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.57 44.0 4.50e-01 98.8% 92.0%
1qlbA03 1.20.58.100 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain 0.57 48.0 4.34e-01 100.0% 66.1%
5b00A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.57 49.0 3.46e-01 97.5% 33.3%
3dkaB01 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.57 43.0 3.66e-01 82.5% 65.2%
2v6eA02 1.20.1440.270 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.56 39.0 3.41e-01 73.8% 76.7%
4fp4A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.54 47.0 3.25e-01 92.5% 39.5%
2z1qB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 44.0 3.72e-01 90.0% 55.1%
3h3mA00 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.54 46.0 4.48e-01 98.8% 87.6%
4xzjA01 3.90.176.10 Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 0.54 43.0 3.26e-01 90.0% 75.4%
1w0bA01 1.20.58.420 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP 0.53 46.0 4.46e-01 100.0% 88.0%
1tqgA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.53 44.0 4.11e-01 96.2% 81.9%
7drjB01 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.52 45.0 3.51e-01 100.0% 51.4%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.51 39.0 3.52e-01 86.3% 66.9%
2xbkA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.50 43.0 2.83e-01 100.0% 67.3%
ECOD (34)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3850425 109.4.1.1602 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › IBN_N, TPR_IMB1 0.71 64.0 3.76e-01 100.0% 14.3%
5032064 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.70 59.0 5.97e-01 100.0% 93.7%
3924442 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.70 62.0 5.62e-01 100.0% 76.4%
3528863 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.69 61.0 5.46e-01 100.0% 74.8%
3968965 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.69 58.0 5.63e-01 100.0% 82.2%
3783043 6155.1.1.2 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.68 60.0 5.80e-01 100.0% 93.3%
3947894 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.67 56.0 5.63e-01 100.0% 91.3%
5045530 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.67 58.0 5.62e-01 97.5% 91.1%
3580283 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.66 57.0 5.69e-01 100.0% 97.6%
4028151 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.65 57.0 5.40e-01 100.0% 85.3%
4554985 3322.1.1.0 alpha bundles › N-terminal domain in fatty acid synthase subunit beta › N-terminal domain in fatty acid synthase subunit beta › N-terminal domain in fatty acid synthase subunit beta 0.65 57.0 4.91e-01 100.0% 63.1%
3585209 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.65 56.0 4.82e-01 100.0% 65.9%
3949864 632.1.1.37 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › DUF6474 0.63 42.0 4.05e-01 80.0% 60.0%
3932693 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.63 56.0 5.49e-01 100.0% 96.5%
3769212 604.1.1.142 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_SYNE1_2 0.63 54.0 4.87e-01 100.0% 81.7%
4955276 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.62 43.0 3.76e-01 71.2% 49.2%
3948847 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.61 53.0 4.94e-01 98.8% 83.0%
4628458 604.1.1.226 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF26877 0.60 53.0 5.23e-01 100.0% 98.8%
148583 109.1.1.1 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C 0.60 51.0 4.59e-01 100.0% 73.3%
3510214 109.1.1.0 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C 0.60 51.0 3.92e-01 100.0% 43.0%
4170026 140.1.1.7 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_2 0.59 46.0 3.91e-01 98.8% 49.3%
3768254 604.3.1.1 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.59 51.0 4.91e-01 100.0% 87.4%
3658574 632.15.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) 0.58 42.0 3.97e-01 78.8% 70.0%
3936980 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.57 50.0 4.01e-01 100.0% 51.5%
3794016 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.56 40.0 2.95e-01 77.5% 55.7%
3246898 109.4.1.1216 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_KNTC1_1st 0.56 49.0 3.20e-01 100.0% 36.3%
3222373 605.4.1.18 alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › PF29357 0.55 40.0 3.93e-01 78.8% 71.8%
3408361 632.23.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Helical linker domain in nicking endonuclease N.BspD6I › Helical linker domain in nicking endonuclease N.BspD6I › DUF4485 0.54 43.0 4.23e-01 96.2% 78.8%
4983940 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.53 40.0 3.51e-01 83.7% 77.0%
3494175 524.1.1.1 alpha arrays › Ypt/Rab-GAP domain of gyp1p-like › Ypt/Rab-GAP domain of gyp1p › Ypt/Rab-GAP domain of gyp1p › RabGAP-TBC 0.52 42.0 3.11e-01 87.5% 45.0%
3691242 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.51 43.0 3.27e-01 96.2% 78.0%
4994150 632.18.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 0.51 42.0 4.01e-01 91.3% 76.8%
3009331 4044.1.1.1 alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Prismane 0.51 43.0 4.25e-01 100.0% 88.0%
3641448 4033.1.1.0 alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like 0.50 41.0 4.04e-01 96.2% 88.2%
D5 medium residues 394-543
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF23275.2 best TPR_23 32.4 1.20e-07 28.7% 17.9%
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1qlbA03 1.20.58.100 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain 0.62 35.0 3.88e-01 75.3% 68.6%
3cf6E03 1.20.870.10 Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 0.61 48.0 5.12e-01 99.3% 94.7%
3zheB02 1.20.190.60 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 0.59 46.0 4.38e-01 100.0% 69.1%
2e9xD01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 38.0 3.99e-01 78.7% 72.3%
5mi7A03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.57 40.0 3.33e-01 82.7% 40.5%
1vdyA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.57 44.0 4.53e-01 99.3% 87.1%
4fx5A03 1.20.120.1690 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.56 30.0 3.54e-01 72.7% 76.0%
4k6jB00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.56 50.0 3.56e-01 100.0% 54.8%
2pywA02 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.55 44.0 3.58e-01 86.7% 99.3%
1q16C01 1.20.950.20 Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C 0.55 37.0 3.36e-01 77.3% 48.6%
3jysA01 1.25.40.390 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.54 43.0 3.82e-01 83.3% 97.3%
3ckcA01 1.25.40.390 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.54 41.0 3.69e-01 82.0% 95.9%
2nwbA02 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 44.0 3.79e-01 89.3% 87.3%
6a95A01 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.52 35.0 3.74e-01 76.0% 79.4%
2iiuA00 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.52 35.0 3.19e-01 71.3% 49.5%
3iv0A00 1.25.40.390 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.52 44.0 3.12e-01 92.0% 47.0%
2ijqA00 1.10.3450.10 Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › TTHA0068-like 0.50 34.0 3.53e-01 100.0% 71.7%
5tgzA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.50 37.0 3.02e-01 76.0% 46.9%
ECOD (23)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3809726 109.4.1.901 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_GCN1 0.64 44.0 3.87e-01 100.0% 45.7%
3577893 603.1.1.135 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › UNC80 0.62 48.0 4.96e-01 88.7% 87.1%
3593529 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 53.0 3.57e-01 98.7% 46.8%
3382904 109.4.1.309 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Med12 0.58 43.0 2.97e-01 100.0% 22.1%
3608382 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.57 45.0 4.17e-01 89.3% 64.6%
3741679 109.4.1.25 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DIL 0.57 51.0 3.73e-01 100.0% 81.4%
3734558 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 50.0 3.03e-01 100.0% 17.1%
3871144 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 44.0 3.91e-01 98.7% 56.3%
5081330 4163.1.1.0 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like 0.54 37.0 3.87e-01 76.7% 76.3%
3227671 5001.1.1.60 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srx 0.54 37.0 3.01e-01 70.0% 66.1%
3203407 192.15.1.0 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.54 37.0 3.44e-01 70.0% 95.8%
3797875 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.53 37.0 2.84e-01 70.7% 67.8%
None 0.53 37.0 2.89e-01 72.0% 69.0%
3923226 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.53 37.0 2.98e-01 72.0% 68.3%
3202126 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.53 37.0 3.29e-01 72.7% 77.8%
3729492 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.52 37.0 3.76e-01 73.3% 75.3%
3998820 5001.1.1.63 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srab 0.52 37.0 2.96e-01 73.3% 46.6%
3608148 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 46.0 3.78e-01 100.0% 60.0%
3723477 109.4.1.356 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.51 44.0 3.11e-01 100.0% 27.9%
3725358 109.4.1.930 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_ECM29_C 0.51 46.0 3.80e-01 100.0% 60.2%
3243109 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.51 35.0 2.80e-01 71.3% 60.3%
3628339 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.50 36.0 2.82e-01 72.0% 60.6%
3224479 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.50 36.0 2.81e-01 73.3% 47.9%
D6 medium residues 544-683_745-759
PDB
Domain cluster: representative
CATH (40)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2mabA00 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.72 44.0 5.21e-01 89.7% 86.2%
5dqqA01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.70 41.0 4.55e-01 91.6% 70.3%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.69 40.0 4.87e-01 85.2% 86.4%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.68 34.0 3.95e-01 85.8% 64.9%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.68 38.0 4.21e-01 87.7% 68.9%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.65 35.0 4.40e-01 84.5% 87.1%
4x28C03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.65 38.0 3.93e-01 88.4% 61.5%
2jifA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.64 37.0 3.80e-01 88.4% 57.1%
3d3mA00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.64 44.0 4.36e-01 83.2% 67.1%
3r2qA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.64 39.0 4.45e-01 91.0% 82.3%
6a3kA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.63 38.0 4.11e-01 89.0% 70.5%
3eabE00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.62 33.0 4.26e-01 83.9% 91.9%
2gsqA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 39.0 4.54e-01 82.6% 89.8%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.61 40.0 4.60e-01 83.9% 88.1%
1s05A00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.61 36.0 3.96e-01 85.8% 70.5%
4gltA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 37.0 4.26e-01 90.3% 82.5%
3jrtA00 1.20.120.1060 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.60 37.0 3.70e-01 91.0% 57.8%
5mdtA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.59 40.0 4.07e-01 86.5% 69.7%
4agsB04 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 37.0 4.00e-01 84.5% 75.9%
1w9rA00 1.20.58.440 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A 0.57 33.0 3.71e-01 92.9% 72.3%
4hyjA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.57 40.0 3.49e-01 70.3% 80.9%
3juiA00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.56 41.0 3.94e-01 83.2% 66.7%
6vqqA01 1.20.1080.10 Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. 0.56 50.0 4.22e-01 99.4% 97.4%
6g28A00 1.10.4080.10 Mainly Alpha › Orthogonal Bundle › ADP-ribosylglycohydrolase fold › ADP-ribosylation/Crystallin J1 0.55 50.0 3.84e-01 100.0% 71.6%
5ts9B00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.55 40.0 4.03e-01 76.1% 100.0%
2c0uA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 38.0 3.67e-01 87.7% 64.5%
1lvfB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 35.0 4.09e-01 88.4% 94.2%
5h5mA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.54 39.0 4.25e-01 73.5% 96.9%
6t0bc02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.54 39.0 3.61e-01 74.2% 66.0%
5mawD00 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.53 39.0 3.26e-01 74.2% 59.6%
2xl4A00 1.20.120.1420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › LntA helical domain 0.53 38.0 3.98e-01 74.8% 86.4%
2m6bA00 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.53 37.0 3.76e-01 71.0% 83.3%
2qtqB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 44.0 4.07e-01 90.3% 93.9%
3a0oA02 1.50.10.100 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase 0.52 37.0 2.87e-01 72.9% 82.5%
1q0gA00 1.20.120.400 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase 0.52 35.0 3.96e-01 80.6% 90.6%
2b1eA04 1.20.1280.170 Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 0.51 36.0 3.97e-01 81.3% 88.2%
1orjD00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.51 34.0 3.82e-01 74.8% 84.8%
1urvA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 37.0 3.74e-01 82.6% 74.7%
1t98A02 1.20.58.590 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain 0.51 43.0 4.30e-01 90.3% 95.7%
5fhiA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.50 38.0 4.00e-01 83.9% 87.1%
ECOD (29)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4878961 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.64 35.0 4.16e-01 87.7% 76.6%
3377749 3843.1.1.15 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › ETR1_N 0.64 34.0 4.21e-01 89.0% 80.0%
3389689 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.63 37.0 3.77e-01 85.8% 57.8%
3741398 632.1.1.8 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › SOG2 0.63 37.0 4.07e-01 87.7% 70.0%
3712596 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.62 53.0 4.83e-01 91.0% 77.0%
3667712 109.3.1.31 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › DUF4220 0.60 43.0 3.60e-01 72.3% 77.0%
3438595 109.3.1.31 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › DUF4220 0.60 42.0 3.64e-01 71.6% 72.3%
4192537 109.4.1.464 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exportin-T 0.59 45.0 3.99e-01 96.8% 54.2%
3245912 109.4.1.64 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › GET4 0.59 51.0 4.05e-01 91.6% 83.0%
5016489 604.39.1.9 alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › Vut_1 0.59 52.0 4.80e-01 96.8% 99.0%
3576126 109.1.1.0 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C 0.58 39.0 4.34e-01 91.6% 84.8%
3929825 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.58 34.0 3.77e-01 87.1% 72.5%
3510885 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.57 48.0 3.47e-01 92.3% 85.7%
3934945 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.56 37.0 3.65e-01 87.1% 61.2%
3498203 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 39.0 3.48e-01 85.2% 49.5%
3518308 109.4.1.1419 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF27567 0.55 45.0 3.46e-01 88.4% 39.2%
3974898 601.4.1.1 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TarH 0.53 38.0 3.71e-01 76.1% 65.1%
3966820 131.1.1.13 alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD_5 0.53 43.0 3.78e-01 87.7% 63.4%
3882493 633.23.1.34 alpha bundles › Bromodomain-like › Claudin › Claudin › CD20 0.52 36.0 3.61e-01 87.7% 68.4%
5035803 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.52 45.0 4.22e-01 93.5% 82.1%
3639718 109.4.1.862 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ZW10_C2 0.52 40.0 2.76e-01 86.5% 21.5%
4335537 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 41.0 3.50e-01 92.9% 52.9%
3276672 604.3.1.1 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.52 39.0 4.27e-01 91.6% 94.6%
3193381 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.51 45.0 3.80e-01 94.8% 70.2%
3735209 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.51 45.0 3.69e-01 94.8% 82.2%
3214393 633.21.1.29 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › PF29123 0.51 35.0 3.62e-01 85.8% 73.3%
3591734 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.50 44.0 3.37e-01 94.2% 49.1%
4587229 5000.4.1.0 alpha arrays › Toxins' membrane translocation domains › delta-Endotoxin (insectocide), N-terminal domain › delta-Endotoxin (insectocide), N-terminal domain 0.50 39.0 3.52e-01 94.8% 60.0%
3682709 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.50 41.0 3.46e-01 86.5% 61.2%
D7 medium residues 684-744
PDB
Domain cluster: representative
CATH (13)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3rmqA02 6.10.140.1650 Special › Helix non-globular › Helix Hairpins › 0.65 32.0 3.40e-01 90.2% 48.2%
2g8lB01 1.10.8.380 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 0.64 39.0 3.84e-01 100.0% 55.2%
2ffjA01 1.10.8.380 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 0.63 37.0 3.83e-01 100.0% 60.7%
2a6cA00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.60 51.0 4.82e-01 100.0% 86.8%
4irlB02 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.58 50.0 4.40e-01 100.0% 88.2%
2e2oA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.57 46.0 3.56e-01 100.0% 50.0%
2oifB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.56 44.0 3.38e-01 100.0% 35.8%
3cxbA03 1.10.1740.30 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Secreted effector protein SifA helical domain 0.55 35.0 3.25e-01 100.0% 48.1%
1yfmA01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.55 41.0 3.38e-01 85.2% 66.7%
4jbeB01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.52 43.0 2.92e-01 100.0% 46.7%
1c3cA01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.51 38.0 3.47e-01 85.2% 80.2%
3b40A02 1.10.287.650 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › L27 domain 0.51 43.0 4.44e-01 98.4% 98.3%
1dofA02 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.50 38.0 3.53e-01 85.2% 72.9%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3948653 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.74 34.0 3.43e-01 88.5% 43.3%
4999903 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.61 35.0 3.34e-01 90.2% 47.1%
1874545 139.4.1.0 few secondary structure elements › Multiheme cytochromes › Outer membrane cytochrome MtrF › Outer membrane cytochrome MtrF 0.61 47.0 2.74e-01 85.2% 11.7%
4016796 509.1.1.0 alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain 0.51 38.0 3.49e-01 88.5% 73.3%