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OP172638.1__WAX05400.1__AD70P2_00012__00012

Bact-Vir

OP172638.1__WAX05400.1__AD70P2_00012__00012

Identity

Accession:
OP172638 ↗
Kingdom:
phage

Quality

92.6 mean pLDDT

Taxonomy

Heunggongvirae› Uroviricota› Caudoviricetes› Guelinviridae› Amedibacillus_phage_AD70P2

TaxID: 2968530

Cluster

View cluster (11 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 45-218
PDB
Domain cluster: representative
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2py5A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.78 75.0 7.39e-01 100.0% 94.6%
7jw2A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.70 64.0 6.01e-01 100.0% 80.0%
3eeqB03 3.30.420.180 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › CobE/GbiG C-terminal domain 0.65 32.0 3.96e-01 100.0% 73.8%
4e1pA00 3.30.60.230 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › Lsr2, dimerisation domain 0.61 17.0 3.01e-01 83.9% 72.7%
7t2sA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.60 54.0 5.43e-01 100.0% 94.3%
2x49A04 3.40.50.12790 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › FHIPEP family, domain 4 0.56 31.0 3.87e-01 100.0% 90.9%
3u3gA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.51 38.0 4.16e-01 86.2% 96.4%
2gtaA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.50 22.0 2.81e-01 72.4% 67.0%
ECOD (22)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3666591 2484.1.1.36 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_2 0.84 80.0 6.95e-01 100.0% 82.0%
4428763 2484.1.1.36 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_2 0.82 78.0 6.88e-01 100.0% 89.6%
4629102 2484.1.1.36 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_2 0.82 78.0 5.56e-01 100.0% 47.8%
4463772 2484.1.1.36 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_2 0.81 78.0 6.60e-01 100.0% 86.0%
3316523 2484.1.1.36 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_2 0.81 78.0 6.77e-01 100.0% 80.0%
4261005 2484.1.1.36 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_2 0.80 77.0 6.51e-01 100.0% 81.9%
3506686 2484.1.1.36 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_2 0.80 77.0 7.02e-01 100.0% 85.0%
4486407 2484.1.1.36 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_2 0.80 77.0 7.38e-01 100.0% 91.3%
4243735 2484.1.1.36 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_2 0.79 76.0 6.79e-01 100.0% 92.2%
4147965 2484.1.1.36 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_2 0.79 76.0 6.56e-01 100.0% 81.6%
11150 2484.1.1.36 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_2 0.78 75.0 7.40e-01 100.0% 95.1%
5081301 2484.1.1.13 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.78 74.0 5.50e-01 100.0% 44.1%
4179220 2484.1.1.144 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DEDD_Tnp_IS110 0.74 48.0 5.61e-01 100.0% 90.4%
3604297 2484.1.1.68 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 0.70 64.0 6.47e-01 100.0% 95.4%
5066483 2484.1.1.68 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 0.70 63.0 6.37e-01 100.0% 96.5%
3598787 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.69 62.0 5.33e-01 100.0% 62.9%
3922908 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.68 64.0 5.72e-01 100.0% 74.3%
3937354 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.68 61.0 5.54e-01 100.0% 72.2%
3798192 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.68 61.0 5.48e-01 100.0% 71.7%
3440342 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.67 41.0 4.96e-01 80.5% 92.2%
3463966 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.65 62.0 5.52e-01 100.0% 81.3%
5077329 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.53 38.0 4.24e-01 96.0% 94.8%
D2 high residues 304-404
PDB
Domain cluster: representative
CATH (19)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2py5A03 3.30.1770.10 Alpha Beta › 2-Layer Sandwich › TPR 1 domain of DNA polymerase › TPR 1 domain of DNA polymerase 0.84 69.0 7.23e-01 100.0% 94.5%
4rr5A02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.67 42.0 5.08e-01 90.1% 100.0%
3bv8A00 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.65 43.0 4.65e-01 97.0% 80.0%
4pxdA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 42.0 4.01e-01 72.3% 100.0%
5huoE01 3.90.1170.20 Alpha Beta › Alpha-Beta Complex › Aldehyde Oxidoreductase; domain 3 › Quinolinate phosphoribosyl transferase, N-terminal domain 0.56 42.0 3.82e-01 79.2% 82.7%
1o4uA01 3.90.1170.20 Alpha Beta › Alpha-Beta Complex › Aldehyde Oxidoreductase; domain 3 › Quinolinate phosphoribosyl transferase, N-terminal domain 0.55 40.0 3.83e-01 76.2% 83.1%
1f2nC00 2.60.120.20 Mainly Beta › Sandwich › Jelly Rolls › 0.54 46.0 3.68e-01 96.0% 84.4%
2jbmD01 3.90.1170.20 Alpha Beta › Alpha-Beta Complex › Aldehyde Oxidoreductase; domain 3 › Quinolinate phosphoribosyl transferase, N-terminal domain 0.54 39.0 3.52e-01 75.2% 78.4%
4ushA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 42.0 4.17e-01 83.2% 88.3%
2q1mA00 2.60.120.40 Mainly Beta › Sandwich › Jelly Rolls › 0.53 43.0 4.20e-01 90.1% 97.4%
1ng0C00 2.60.120.20 Mainly Beta › Sandwich › Jelly Rolls › 0.53 45.0 3.57e-01 96.0% 84.9%
1cwpA00 2.60.120.220 Mainly Beta › Sandwich › Jelly Rolls › Satellite virus coat domain 0.52 44.0 3.91e-01 94.1% 89.3%
2dt4A00 3.30.1330.80 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › Hypothetical protein, similar to alpha- acetolactate decarboxylase; domain 2 0.52 46.0 4.15e-01 100.0% 84.6%
1tyjA00 2.60.40.680 Mainly Beta › Sandwich › Immunoglobulin-like › 0.52 42.0 3.62e-01 89.1% 88.2%
6h8oA00 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.52 34.0 3.58e-01 86.1% 72.6%
3ce8A00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 40.0 4.23e-01 88.1% 92.1%
2b59A00 2.60.40.680 Mainly Beta › Sandwich › Immunoglobulin-like › 0.51 42.0 3.58e-01 89.1% 88.0%
2pn5A10 2.60.40.690 Mainly Beta › Sandwich › Immunoglobulin-like › Alpha-macroglobulin, receptor-binding domain 0.51 39.0 3.48e-01 82.2% 79.5%
1apsA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.50 41.0 4.18e-01 91.1% 88.8%
ECOD (27)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
86600 4968.1.1.1 ↗ a+b complex topology › insertion domain in bacteriophage phi29 DNA polymerase › insertion domain in bacteriophage phi29 DNA polymerase › insertion domain in bacteriophage phi29 DNA polymerase › DNA_pol_B_2 0.84 69.0 7.31e-01 100.0% 95.6%
3506687 304.48.1.17 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B_2 0.76 71.0 4.54e-01 100.0% 27.2%
3718568 304.102.1.0 ↗ a+b two layers › Alpha-beta plaits › Pseudouridine synthase › Pseudouridine synthase 0.60 51.0 4.01e-01 93.1% 70.9%
3235415 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.59 45.0 4.70e-01 80.2% 100.0%
3988637 304.7.1.2 ↗ a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors › Inhibitor_I9 0.58 39.0 4.52e-01 94.1% 97.1%
5038508 304.8.1.4 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C 0.58 46.0 4.96e-01 84.2% 100.0%
3282319 304.7.1.0 ↗ a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors 0.58 46.0 4.15e-01 86.1% 94.4%
3679719 304.147.1.0 ↗ a+b two layers › Alpha-beta plaits › Tetrahydrodipicolinate acetyltransferase N-terminal domain › Tetrahydrodipicolinate acetyltransferase N-terminal domain 0.57 39.0 4.45e-01 89.1% 100.0%
3454149 4111.1.1.2 ↗ a+b two layers › AF0104/ALDC/Ptd012-like › AF0104/ALDC/Ptd012-like › AF0104/ALDC/Ptd012-like › PCC 0.57 50.0 4.52e-01 96.0% 90.4%
3648276 4111.1.1.2 ↗ a+b two layers › AF0104/ALDC/Ptd012-like › AF0104/ALDC/Ptd012-like › AF0104/ALDC/Ptd012-like › PCC 0.56 49.0 4.59e-01 96.0% 88.8%
3595076 304.102.1.0 ↗ a+b two layers › Alpha-beta plaits › Pseudouridine synthase › Pseudouridine synthase 0.55 46.0 3.42e-01 92.1% 74.4%
3590219 304.5.1.7 ↗ a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF2179 0.55 42.0 4.40e-01 96.0% 88.9%
3658946 304.7.1.2 ↗ a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors › Inhibitor_I9 0.55 42.0 4.52e-01 92.1% 95.3%
5051003 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.53 46.0 4.48e-01 94.1% 100.0%
5015637 304.5.1.0 ↗ a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like 0.53 38.0 4.23e-01 91.1% 96.2%
3494380 269.1.1.3 ↗ a+b complex topology › Fibrinogen C-terminal domain-like › Fibrinogen C-terminal domain-like › Fibrinogen C-terminal domain-like › COLFI 0.53 45.0 3.61e-01 95.0% 94.6%
3386278 11.1.5.66 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › DUF5416 0.52 41.0 3.93e-01 84.2% 91.5%
5043890 304.4.1.1 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.52 38.0 4.11e-01 90.1% 90.6%
5079777 304.4.1.1 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.52 37.0 4.11e-01 95.0% 95.0%
154632 321.1.1.1 ↗ a+b two layers › Glutamine synthetase-like › Glutamine synthetase/guanido kinase › Glutamine synthetase/guanido kinase › Gln-synt_C 0.51 39.0 2.78e-01 80.2% 74.8%
4963243 304.3.1.0 ↗ a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.51 33.0 3.79e-01 70.3% 92.9%
5009749 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.51 37.0 3.96e-01 93.1% 86.7%
5054197 304.16.1.1 ↗ a+b two layers › Alpha-beta plaits › eEF-1beta-like › eEF-1beta-like › EF1_GNE 0.51 38.0 4.18e-01 89.1% 100.0%
5045160 304.4.1.1 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.51 36.0 3.98e-01 92.1% 94.9%
3500612 2004.1.1.250 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd 0.51 42.0 2.93e-01 90.1% 53.6%
4942895 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.50 37.0 4.17e-01 90.1% 98.8%
3741350 11.2.1.41 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2_TCB1 0.50 40.0 3.72e-01 89.1% 94.8%
D3 medium residues 231-279_472-521_541-561
PDB
Domain cluster: representative
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2py5A02 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.60 54.0 4.67e-01 96.7% 72.1%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3820510 149.1.1.1 ↗ alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 0.52 43.0 2.90e-01 89.2% 80.0%
D4 medium residues 280-303_522-540_562-622
PDB
Domain cluster: representative
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2py5A02 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.89 69.0 5.61e-01 80.8% 72.6%
2gv9B04 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.81 64.0 5.05e-01 82.7% 98.0%
1q8iA04 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.79 63.0 4.90e-01 83.7% 71.3%
1s5jA03 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.78 63.0 5.34e-01 83.7% 96.2%
4fxdA05 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.70 54.0 5.14e-01 79.8% 91.5%
2do3A01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.61 27.0 3.62e-01 76.9% 80.4%
4m4zA01 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.60 26.0 3.69e-01 73.1% 89.4%
6bhdA03 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.57 26.0 3.28e-01 80.8% 69.8%
1lckA01 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.56 28.0 3.58e-01 76.0% 84.7%
3i35A00 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.56 28.0 3.63e-01 76.0% 87.7%
5i2cB01 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.50 43.0 3.91e-01 97.1% 93.2%
2evrA01 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.50 28.0 3.26e-01 79.8% 77.0%
ECOD (16)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4942685 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.84 65.0 4.05e-01 79.8% 43.9%
5017083 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.84 64.0 4.55e-01 78.8% 83.0%
3784383 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.82 63.0 4.19e-01 79.8% 68.6%
3480546 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.80 64.0 4.60e-01 82.7% 95.1%
4956224 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.80 64.0 4.73e-01 82.7% 88.5%
3466667 2484.1.1.161 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.80 67.0 3.96e-01 87.5% 33.4%
3582653 304.48.1.17 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B_2 0.78 73.0 5.84e-01 100.0% 66.8%
4282509 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.77 65.0 3.93e-01 87.5% 30.4%
4629102 2484.1.1.36 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_2 0.77 72.0 4.57e-01 100.0% 28.5%
4243736 304.48.1.17 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B_2 0.77 72.0 6.07e-01 100.0% 75.2%
4674811 304.48.1.17 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B_2 0.76 71.0 4.89e-01 100.0% 77.1%
3680878 304.48.1.17 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B_2 0.75 70.0 4.86e-01 100.0% 79.1%
4365778 304.48.1.17 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B_2 0.75 70.0 5.03e-01 100.0% 76.1%
4264107 304.48.1.17 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B_2 0.75 69.0 4.87e-01 100.0% 73.7%
4321860 304.48.1.17 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B_2 0.73 68.0 5.48e-01 100.0% 68.9%
3481726 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.52 26.0 3.33e-01 73.1% 83.3%
D5 medium residues 405-457
PDB
Domain cluster: representative
CATH (29)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2vgxB00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.84 61.0 4.38e-01 77.4% 29.0%
3qf7A02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.81 65.0 6.20e-01 88.7% 95.2%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.80 62.0 5.67e-01 84.9% 85.9%
2gv9A05 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.78 64.0 6.19e-01 90.6% 96.6%
2jdiG01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.78 61.0 5.84e-01 84.9% 73.8%
3k6tB00 1.20.5.4010 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.75 54.0 5.61e-01 79.2% 91.8%
1xjaB00 2.60.120.280 Mainly Beta › Sandwich › Jelly Rolls › Regulatory protein AraC 0.75 58.0 4.20e-01 86.8% 29.9%
4h63K00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 59.0 4.84e-01 92.5% 66.3%
4jvyB00 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.69 51.0 3.53e-01 81.1% 23.7%
2yevA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.68 54.0 4.93e-01 90.6% 66.2%
2p6vA00 1.20.120.1110 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › TAFH/NHR1 domain 0.67 46.0 3.84e-01 86.8% 40.2%
4fvmA06 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.67 50.0 5.17e-01 84.9% 100.0%
3zdmB00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.67 49.0 5.02e-01 84.9% 86.0%
4fppB01 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.66 53.0 4.95e-01 94.3% 83.1%
1lrzA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 50.0 4.87e-01 88.7% 98.4%
3tklB01 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 50.0 4.82e-01 88.7% 82.3%
2xzmO02 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.64 50.0 4.67e-01 90.6% 71.4%
3sfvB02 6.10.140.2010 Special › Helix non-globular › Helix Hairpins › 0.63 50.0 3.50e-01 94.3% 70.5%
3lnnB03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.62 48.0 4.55e-01 88.7% 76.1%
2pvqA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.62 48.0 3.97e-01 90.6% 54.7%
2lhrA00 1.20.58.1270 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 42.0 3.82e-01 75.5% 53.8%
6xkyA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.59 47.0 3.31e-01 94.3% 82.4%
4i43B02 3.30.43.40 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 › Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain 0.58 46.0 3.68e-01 90.6% 42.1%
4asvA00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.57 42.0 3.80e-01 81.1% 55.7%
8igrI01 2.40.270.10 Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 0.56 45.0 3.25e-01 96.2% 80.1%
1tmxB00 2.60.130.10 Mainly Beta › Sandwich › Protocatechuate 3,4-Dioxygenase, subunit A › Aromatic compound dioxygenase 0.55 42.0 2.71e-01 84.9% 72.8%
1b04A03 1.10.287.610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.55 42.0 4.08e-01 88.7% 75.8%
3behB01 1.20.120.540 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels 0.55 44.0 3.61e-01 100.0% 52.1%
1w36D03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 40.0 2.98e-01 90.6% 78.0%
ECOD (13)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4015147 2004.1.1.430 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran, ABC_tran_Xtn 0.76 60.0 3.38e-01 86.8% 7.8%
4646268 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.76 61.0 5.59e-01 88.7% 68.6%
3825716 375.1.1.26 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2 0.76 61.0 4.66e-01 88.7% 40.0%
3343376 616.1.1.0 ↗ alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain 0.75 52.0 5.52e-01 73.6% 100.0%
4888564 6067.1.1.1 ↗ alpha arrays › Dimerization domain of Sgt2 › Dimerization domain of Sgt2 › Dimerization domain of Sgt2 › SGTA_dimer 0.74 52.0 4.33e-01 83.0% 41.7%
3232471 3652.1.1.2 ↗ alpha duplicates or obligate multimers › Qua1 › Qua1 › Qua1 › STAR_dimer 0.70 54.0 5.21e-01 84.9% 80.0%
3917245 632.6.1.6 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit › Med15_M 0.70 54.0 4.92e-01 83.0% 61.4%
3551336 103.4.1.17 ↗ alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Med15_M 0.69 55.0 4.94e-01 88.7% 62.7%
4774645 4246.1.1.2 ↗ a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.68 56.0 3.98e-01 96.2% 53.8%
3843 604.14.1.1 ↗ alpha bundles › Spectrin repeat-like › PPK N-terminal domain-like › PPK N-terminal domain-like › PP_kinase_N 0.67 50.0 4.25e-01 84.9% 55.3%
4373408 3757.1.1.0 ↗ extended segments › AF1503 pre-HAMP domain › AF1503 pre-HAMP domain › AF1503 pre-HAMP domain 0.60 44.0 4.64e-01 88.7% 97.8%
3955184 3831.1.1.1 ↗ alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › LprI 0.60 46.0 4.09e-01 90.6% 56.5%
3483522 101.35.1.0 ↗ alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX 0.55 43.0 3.19e-01 88.7% 72.7%
D6 medium residues 623-681
PDB
Domain cluster: representative
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3gw6A03 3.30.2460.10 Alpha Beta › 2-Layer Sandwich › Endo-n-acetylneuraminidase fold › Endo-n-acetylneuraminidase domain 0.65 41.0 4.17e-01 100.0% 66.7%
4f0aB02 3.30.2460.20 Alpha Beta › 2-Layer Sandwich › Endo-n-acetylneuraminidase fold › Wnt (Wingless and Int-1), C-terminal domain 0.59 36.0 3.50e-01 89.8% 52.9%
8bddA02 2.70.98.70 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.55 38.0 2.42e-01 72.9% 72.8%
3pfeA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 37.0 3.00e-01 72.9% 76.2%
1dwnA00 3.30.380.10 Alpha Beta › 2-Layer Sandwich › MS2 Viral Coat Protein › MS2 Viral Coat Protein 0.54 30.0 2.37e-01 71.2% 23.6%
2iieA01 4.10.520.10 Few Secondary Structures › Irregular › HU Protein; Chain A › IHF-like DNA-binding proteins 0.54 35.0 2.97e-01 71.2% 36.1%
3lvtA03 2.60.40.2210 Mainly Beta › Sandwich › Immunoglobulin-like › 0.53 37.0 2.91e-01 74.6% 62.0%
ECOD (7)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3249604 2484.1.1.9 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve 0.59 42.0 2.95e-01 78.0% 90.9%
4260211 4967.1.1.6 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2 0.57 42.0 3.37e-01 100.0% 38.0%
6518 265.1.1.1 ↗ a+b two layers › RNA bacteriophage capsid protein › RNA bacteriophage capsid protein › RNA bacteriophage capsid protein › Levi_coat 0.55 31.0 2.40e-01 71.2% 22.5%
3471203 2011.1.1.8 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M28 0.54 41.0 2.62e-01 84.7% 40.6%
3646354 11.1.5.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f 0.54 37.0 3.08e-01 72.9% 60.0%
4681823 101.17.1.1 ↗ alpha arrays › HTH › IHF-like DNA-binding proteins › IHF-like DNA-binding proteins › Bac_DNA_binding 0.52 34.0 2.92e-01 71.2% 39.0%
4857726 704.1.1.0 ↗ beta complex topology › Coronavirus RNA-binding domain (N-terminal part of Pfam 00937) › Coronavirus RNA-binding domain (N-terminal part of Pfam 00937) › Coronavirus RNA-binding domain (N-terminal part of Pfam 00937) 0.51 35.0 2.78e-01 72.9% 50.0%