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OP172776.1__WAX12153.1__CS266P2_00025__00025

Bact-Vir

OP172776.1__WAX12153.1__CS266P2_00025__00025

Identity

Accession:
OP172776 ↗
Kingdom:
phage

Quality

85.5 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 57-118
PDB
Domain cluster: representative
CATH (78)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.97 92.0 7.33e-01 100.0% 56.4%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.94 90.0 7.64e-01 100.0% 67.4%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.92 84.0 5.47e-01 100.0% 25.8%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.91 79.0 6.84e-01 95.2% 63.7%
2lm9A00 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.90 83.0 7.08e-01 100.0% 64.6%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.90 82.0 7.71e-01 100.0% 83.6%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.90 84.0 6.83e-01 100.0% 57.9%
1cxzB00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.90 84.0 7.40e-01 100.0% 72.1%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.89 82.0 7.61e-01 100.0% 81.8%
3behB01 1.20.120.540 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels 0.89 68.0 5.38e-01 83.9% 42.7%
1vp7A00 1.10.287.1040 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Exonuclease VII, small subunit 0.88 64.0 6.19e-01 75.8% 69.1%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.88 70.0 6.61e-01 88.7% 71.6%
1x4tA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.88 71.0 7.37e-01 87.1% 93.1%
2gscC00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.87 70.0 5.65e-01 93.5% 48.2%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.86 60.0 5.53e-01 72.6% 61.0%
3cazB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.86 78.0 5.26e-01 98.4% 49.0%
1gaxA05 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.86 77.0 7.31e-01 98.4% 87.7%
3uumA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.86 77.0 6.13e-01 100.0% 52.5%
7ymiZ01 1.10.287.740 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre 0.85 62.0 6.36e-01 75.8% 100.0%
5ffdA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.85 72.0 5.50e-01 95.2% 41.6%
5z7qA00 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.85 77.0 5.47e-01 100.0% 39.8%
4nb5B02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.85 71.0 7.03e-01 90.3% 89.1%
2rkhA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.85 76.0 7.07e-01 98.4% 78.9%
2itbB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.84 71.0 4.89e-01 91.9% 28.8%
4mtxD00 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.84 77.0 6.60e-01 100.0% 65.3%
6yz2A01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.84 78.0 6.08e-01 98.4% 50.8%
3d36B02 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.84 69.0 6.98e-01 93.5% 90.2%
7zxkC01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.84 64.0 4.78e-01 82.3% 100.0%
1urfA00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.84 75.0 6.84e-01 98.4% 81.5%
1cunA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.84 73.0 6.16e-01 100.0% 58.8%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.81 63.0 4.46e-01 88.7% 28.5%
2c5iT00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.81 67.0 5.85e-01 91.9% 67.0%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.80 71.0 6.53e-01 100.0% 77.8%
3pe0A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.80 70.0 5.94e-01 100.0% 59.4%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.79 71.0 6.02e-01 100.0% 62.7%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.79 69.0 5.83e-01 100.0% 57.9%
3txsC01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.79 69.0 6.51e-01 100.0% 86.7%
1vctA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.78 65.0 5.43e-01 100.0% 53.2%
2kwhA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 61.0 6.35e-01 91.9% 92.9%
4l8jA04 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.78 64.0 6.57e-01 96.8% 94.9%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.78 68.0 5.61e-01 98.4% 58.2%
3nyjA00 1.20.120.770 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Amyloid precursor protein, E2 domain 0.77 67.0 4.85e-01 100.0% 35.4%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.77 59.0 5.37e-01 87.1% 61.2%
3l9fA02 6.10.140.1570 Special › Helix non-globular › Helix Hairpins › 0.77 64.0 5.96e-01 100.0% 72.8%
4e6nA02 6.10.140.1010 Special › Helix non-globular › Helix Hairpins › 0.77 65.0 6.45e-01 100.0% 89.4%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.77 68.0 6.06e-01 100.0% 83.0%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.76 69.0 5.55e-01 100.0% 82.9%
2rp4A00 6.10.280.60 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain 0.76 56.0 5.42e-01 88.7% 69.0%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.76 66.0 6.27e-01 100.0% 86.7%
2lw1A00 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.76 66.0 6.01e-01 98.4% 76.5%
4h63K00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.76 66.0 5.69e-01 98.4% 62.2%
3qweA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.76 65.0 4.29e-01 100.0% 23.5%
8b9zK01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.76 58.0 5.07e-01 85.5% 56.0%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.76 64.0 4.29e-01 100.0% 24.0%
1st6A03 1.20.120.810 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle 0.75 65.0 4.41e-01 98.4% 27.5%
3pe0A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 64.0 5.42e-01 98.4% 71.7%
1vf7A03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.73 59.0 6.00e-01 95.2% 93.3%
2ficB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.73 64.0 4.51e-01 100.0% 33.3%
3uarA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.73 59.0 4.99e-01 90.3% 57.9%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.73 61.0 5.89e-01 98.4% 84.5%
2hh7A00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.72 58.0 5.21e-01 87.1% 63.5%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.72 56.0 5.11e-01 87.1% 65.9%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.72 62.0 4.50e-01 100.0% 36.1%
2qvaA01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.70 56.0 4.44e-01 100.0% 42.6%
2pvqA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.70 59.0 4.99e-01 96.8% 57.5%
1zbtA01 6.10.140.1950 Special › Helix non-globular › Helix Hairpins › 0.69 56.0 5.17e-01 95.2% 69.9%
3wctD00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.68 46.0 3.47e-01 71.0% 32.0%
4gzrC00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.68 59.0 6.03e-01 100.0% 98.4%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.67 54.0 4.84e-01 91.9% 64.5%
4wqoD00 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.67 57.0 4.34e-01 91.9% 86.5%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.67 57.0 5.39e-01 100.0% 78.2%
2db7A01 6.10.250.980 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.67 52.0 5.48e-01 98.4% 100.0%
4okvE00 6.10.140.1890 Special › Helix non-globular › Helix Hairpins › 0.66 55.0 5.48e-01 98.4% 89.2%
6xxvC00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.66 59.0 4.84e-01 100.0% 56.8%
2cazD00 6.10.140.820 Special › Helix non-globular › Helix Hairpins › 0.64 51.0 5.18e-01 91.9% 95.0%
2yevA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 50.0 4.77e-01 96.8% 74.3%
2qfcA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.63 53.0 3.41e-01 90.3% 33.5%
3lwjA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.59 52.0 3.67e-01 98.4% 46.1%
ECOD (75)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3269429 603.2.1.2 ↗ alpha bundles › STAT-like › STAT › STAT › Dict-STAT-coil 0.98 94.0 7.33e-01 100.0% 53.9%
3473142 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.95 90.0 6.63e-01 100.0% 44.3%
3382780 2006.1.1.8 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › 5_nucleotid 0.95 90.0 5.38e-01 100.0% 17.7%
3215465 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.94 88.0 6.72e-01 100.0% 47.7%
139445 622.4.1.1 ↗ alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › Blo-t-5 0.94 90.0 7.37e-01 100.0% 61.4%
3619575 192.5.1.1 ↗ alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 0.94 88.0 7.93e-01 100.0% 77.5%
None — 0.93 84.0 5.02e-01 100.0% 16.6%
5057547 5054.1.1.0 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.93 76.0 6.28e-01 85.5% 53.0%
3962991 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.93 87.0 5.89e-01 100.0% 31.8%
4946455 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.93 87.0 7.86e-01 100.0% 83.7%
5030987 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.92 86.0 7.81e-01 100.0% 77.5%
4259224 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.92 85.0 6.18e-01 100.0% 40.0%
4311810 605.1.1.1 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.92 85.0 7.94e-01 100.0% 82.7%
3971224 223.1.1.0 ↗ a+b three layers › Profilin-like › sensor domains › sensor domains 0.92 86.0 5.63e-01 100.0% 28.0%
5047356 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.91 82.0 8.06e-01 96.8% 92.3%
4990488 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.90 80.0 6.64e-01 100.0% 58.0%
3294437 5086.1.1.110 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HisKA 0.90 83.0 7.57e-01 100.0% 78.8%
3243299 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.90 74.0 7.07e-01 88.7% 77.1%
4994917 3834.1.1.25 ↗ alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain › DUF7121 0.90 83.0 5.36e-01 100.0% 25.3%
3604531 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.89 82.0 6.39e-01 100.0% 49.6%
4959390 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.89 82.0 7.88e-01 100.0% 90.0%
3339561 605.1.1.1 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.89 82.0 6.90e-01 100.0% 63.0%
3968144 605.1.1.1 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.89 70.0 6.94e-01 83.9% 86.2%
3631949 309.1.2.5 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › ThrRS/AlaRS editing domain › Seryl_tRNA_N 0.88 82.0 6.34e-01 100.0% 49.6%
3972236 3755.3.1.42 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › CheZ 0.88 80.0 5.63e-01 100.0% 34.4%
4033238 101.1.2.804 ↗ alpha arrays › HTH › HTH › winged helix domain › PF27113 0.88 81.0 5.72e-01 100.0% 49.1%
4013672 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.88 80.0 6.72e-01 100.0% 63.0%
3969538 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.88 70.0 7.42e-01 90.3% 96.4%
3988454 605.1.1.1 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.87 74.0 7.10e-01 90.3% 80.0%
3251379 605.1.1.1 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.87 79.0 7.07e-01 100.0% 72.9%
4883924 605.1.1.1 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.87 79.0 7.23e-01 100.0% 78.8%
4210642 3755.1.1.12 ↗ alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › CheZ 0.86 77.0 6.02e-01 100.0% 47.7%
3931883 4006.1.1.1 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.86 78.0 6.35e-01 100.0% 57.3%
3968484 605.1.1.1 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.85 79.0 7.53e-01 100.0% 88.6%
3973000 223.1.1.0 ↗ a+b three layers › Profilin-like › sensor domains › sensor domains 0.85 77.0 5.38e-01 100.0% 33.2%
3725261 4177.1.1.1 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.85 76.0 4.83e-01 100.0% 25.8%
3257797 605.1.1.1 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.85 76.0 5.06e-01 100.0% 26.8%
3810882 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.84 73.0 4.68e-01 100.0% 21.5%
5070059 3834.1.1.25 ↗ alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain › DUF7121 0.84 76.0 4.94e-01 100.0% 79.2%
3973899 5086.1.1.92 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE 0.83 67.0 5.08e-01 100.0% 37.9%
2409294 601.52.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › Flagellar hook-associated protein 1 helical domain › Flagellar hook-associated protein 1 helical domain › Flagellin_N 0.83 76.0 5.80e-01 100.0% 53.3%
4232718 4006.1.1.1 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.83 74.0 6.24e-01 100.0% 61.0%
3660998 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.83 72.0 4.27e-01 96.8% 21.3%
3691039 605.1.1.1 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.83 75.0 6.86e-01 100.0% 77.5%
3957419 605.1.1.1 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.82 75.0 6.98e-01 100.0% 88.0%
3456370 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.82 74.0 5.44e-01 100.0% 65.2%
3231463 632.8.1.2 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › Alpha-2-MRAP_C 0.81 70.0 6.18e-01 100.0% 65.3%
3971539 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.81 73.0 6.87e-01 100.0% 84.0%
3435097 4177.1.1.11 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › DUF632 0.80 70.0 4.61e-01 100.0% 23.8%
3551506 4177.1.1.1 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.80 71.0 4.53e-01 100.0% 21.0%
1291200 4177.1.1.1 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.79 71.0 4.51e-01 100.0% 21.7%
3166260 1.1.7.123 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › PF25885 0.79 68.0 5.33e-01 100.0% 45.4%
3967813 5086.1.1.93 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_EMRA 0.79 69.0 5.35e-01 100.0% 45.4%
3947564 605.1.1.4 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 0.79 68.0 6.75e-01 96.8% 92.3%
3613914 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.79 68.0 6.50e-01 100.0% 90.7%
3545387 3602.1.1.0 ↗ alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain 0.79 67.0 5.64e-01 100.0% 55.5%
3987006 5086.1.1.93 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_EMRA 0.79 69.0 5.22e-01 100.0% 42.1%
5060491 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.79 67.0 5.39e-01 100.0% 49.2%
3473827 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.79 65.0 6.61e-01 91.9% 100.0%
4362754 5086.1.1.86 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YBHG 0.78 67.0 5.38e-01 98.4% 48.3%
3974625 5086.1.1.84 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.78 68.0 6.54e-01 100.0% 84.3%
3974231 5086.1.1.84 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.78 68.0 6.51e-01 100.0% 84.3%
4006721 325.1.7.50 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › PF25876 0.78 67.0 6.01e-01 100.0% 69.4%
3740490 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.78 66.0 4.54e-01 100.0% 27.4%
4010479 325.1.7.48 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › PF25885 0.78 67.0 5.22e-01 100.0% 45.4%
4525341 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.78 67.0 6.46e-01 100.0% 84.3%
3631218 622.4.1.0 ↗ alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.77 67.0 5.84e-01 100.0% 64.2%
3713201 4323.1.1.1 ↗ alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.76 65.0 5.06e-01 100.0% 43.4%
3971349 5086.1.1.84 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.76 64.0 6.49e-01 96.8% 95.0%
3386973 5086.1.1.84 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.75 65.0 5.84e-01 100.0% 81.1%
3619662 192.12.1.3 ↗ alpha bundles › Long alpha-hairpin › Transcriptional repressor TraM › Transcriptional repressor TraM › DUF747 0.75 65.0 6.01e-01 100.0% 80.0%
4045132 192.8.1.0 ↗ alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.74 63.0 5.37e-01 100.0% 92.7%
3971758 5086.1.1.84 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.74 63.0 5.81e-01 100.0% 89.4%
3906467 1008.1.1.106 ↗ alpha bundles › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › CSN5_C 0.72 64.0 5.64e-01 100.0% 86.7%
3428852 3755.4.1.0 ↗ alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.71 60.0 4.83e-01 100.0% 49.6%
D2 medium residues 4-56
PDB
Domain cluster: representative
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2b9dA01 3.30.160.330 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.68 45.0 4.91e-01 71.7% 94.9%
7wq5A01 3.30.730.10 Alpha Beta › 2-Layer Sandwich › GCC-box Binding Domain › AP2/ERF domain 0.63 44.0 4.30e-01 73.6% 77.6%
4e1pA00 3.30.60.230 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › Lsr2, dimerisation domain 0.60 42.0 4.24e-01 84.9% 74.5%
2jvfA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.57 45.0 3.82e-01 90.6% 100.0%
5ja1B00 3.90.820.10 Alpha Beta › Alpha-Beta Complex › Rubredoxin-like › Structural Genomics, Unknown Function 30-nov-00 1gh9 Mol_id 0.56 44.0 4.22e-01 90.6% 87.9%
2qrdE01 3.10.580.10 Alpha Beta › Roll › CBS-domain › CBS-domain 0.56 41.0 2.96e-01 81.1% 81.7%
3hluA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 39.0 3.60e-01 75.5% 91.8%
7essA01 3.30.420.140 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain 0.56 43.0 3.38e-01 92.5% 94.7%
1wisA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 38.0 3.20e-01 75.5% 65.3%
1i5eA00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.55 39.0 2.68e-01 77.4% 83.7%
3cjeA00 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.54 37.0 2.82e-01 77.4% 70.7%
3fdfA02 6.10.140.550 Special › Helix non-globular › Helix Hairpins › 0.53 37.0 3.67e-01 73.6% 69.6%
1j4wA01 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.52 40.0 3.71e-01 88.7% 100.0%
6l3tA01 1.20.1440.80 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Gap junction channel protein cysteine-rich domain 0.52 36.0 2.56e-01 77.4% 23.6%
4divV01 2.40.30.200 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.51 38.0 2.98e-01 86.8% 92.0%
2hj1A00 3.10.20.280 Alpha Beta › Roll › Ubiquitin-like (UB roll) › RnfH-like 0.51 35.0 3.18e-01 75.5% 70.1%
4n01A01 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.50 35.0 2.85e-01 77.4% 100.0%
ECOD (13)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3369184 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.67 47.0 4.16e-01 75.5% 87.5%
3446681 252.2.1.0 ↗ a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.63 44.0 4.51e-01 75.5% 94.0%
3565043 327.11.2.1 ↗ a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 0.63 43.0 3.63e-01 73.6% 75.8%
3380188 252.2.1.1 ↗ a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 0.62 42.0 4.25e-01 71.7% 81.8%
3731895 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.60 42.0 3.95e-01 77.4% 60.9%
3370160 207.1.1.97 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_RPS2 0.58 39.0 2.60e-01 71.7% 15.5%
3601659 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.57 40.0 3.09e-01 79.2% 32.0%
5052024 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.56 38.0 3.41e-01 73.6% 95.3%
3267490 101.1.2.24 ↗ alpha arrays › HTH › HTH › winged helix domain › MAGE 0.53 39.0 2.60e-01 81.1% 63.0%
3170675 1013.1.1.0 ↗ beta duplicates or obligate multimers › WD repeat-containing protein 48 ancillary domain › WD repeat-containing protein 48 ancillary domain › WD repeat-containing protein 48 ancillary domain 0.53 41.0 2.95e-01 96.2% 83.0%
4344942 10.9.1.3 ↗ beta sandwiches › jelly-roll › C-terminal domain of mullusc hemocyanin › C-terminal domain of mullusc hemocyanin › Tyrosinase_C 0.52 41.0 3.12e-01 94.3% 74.0%
4032562 1.1.13.4 ↗ beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › Sipho_tail 0.51 35.0 2.76e-01 75.5% 97.7%
4297859 314.1.1.2 ↗ a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA-synt_2b 0.50 44.0 2.73e-01 100.0% 59.0%