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OP172779.1__WAX12392.1__DO134P1_00054__00053
Bact-VirOP172779.1__WAX12392.1__DO134P1_00054__00053
Identity
- Accession:
- OP172779 ↗
- Kingdom:
- phage
Quality
73.0
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 3-145_236-304
Domain cluster:
representative
CATH (50)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3s84A02 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.80 | 56.0 | 6.41e-01 | 81.1% | 94.3% |
| 1m6nA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.70 | 39.0 | 4.76e-01 | 77.4% | 83.7% |
| 3ljbA00 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.69 | 61.0 | 6.10e-01 | 93.4% | 91.8% |
| 4mk6A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.68 | 39.0 | 4.13e-01 | 83.0% | 61.7% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.68 | 39.0 | 4.82e-01 | 94.3% | 89.5% |
| 4f4cA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.67 | 62.0 | 4.23e-01 | 99.1% | 93.0% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.65 | 37.0 | 4.77e-01 | 80.2% | 99.1% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.63 | 35.0 | 4.63e-01 | 81.6% | 100.0% |
| 8etcb01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.63 | 41.0 | 4.87e-01 | 92.9% | 95.2% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.62 | 37.0 | 4.56e-01 | 95.8% | 94.6% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.61 | 37.0 | 4.58e-01 | 98.6% | 99.2% |
| 1avoB00 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.61 | 37.0 | 4.42e-01 | 83.5% | 89.3% |
| 3ripA02 | 1.20.120.1900 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Gamma-tubulin complex, C-terminal domain | 0.60 | 42.0 | 3.80e-01 | 89.6% | 52.3% |
| 3m9vA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.60 | 33.0 | 3.72e-01 | 70.8% | 68.2% |
| 3pltA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.60 | 49.0 | 4.89e-01 | 84.0% | 99.1% |
| 2e87A01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.60 | 42.0 | 4.74e-01 | 79.2% | 93.1% |
| 2efkA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.59 | 47.0 | 4.42e-01 | 83.0% | 88.9% |
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.59 | 47.0 | 4.36e-01 | 83.0% | 81.2% |
| 4o6mA02 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.59 | 37.0 | 3.86e-01 | 83.5% | 67.2% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.59 | 34.0 | 4.37e-01 | 80.7% | 99.2% |
| 2wb7A03 | 1.20.120.870 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain | 0.59 | 36.0 | 4.32e-01 | 93.4% | 92.6% |
| 3qweA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.58 | 48.0 | 4.47e-01 | 84.9% | 88.1% |
| 8a1gC01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.58 | 45.0 | 4.88e-01 | 83.0% | 95.0% |
| 7aalA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.58 | 46.0 | 4.26e-01 | 82.5% | 87.2% |
| 5tgzA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.58 | 39.0 | 3.49e-01 | 90.6% | 48.3% |
| 1x04A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.58 | 46.0 | 4.73e-01 | 82.5% | 90.0% |
| 2ficB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.57 | 45.0 | 4.65e-01 | 81.6% | 92.0% |
| 3rh3A01 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.57 | 35.0 | 4.24e-01 | 80.2% | 94.0% |
| 1wp1B01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.57 | 42.0 | 3.49e-01 | 74.1% | 85.0% |
| 4wpcA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.57 | 45.0 | 4.11e-01 | 83.0% | 79.2% |
| 3cazB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.57 | 45.0 | 4.56e-01 | 83.0% | 91.4% |
| 2d1lA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.56 | 46.0 | 4.40e-01 | 86.3% | 83.1% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.56 | 34.0 | 3.92e-01 | 93.9% | 81.7% |
| 3g9gA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.55 | 43.0 | 4.13e-01 | 82.5% | 80.8% |
| 5z7qA00 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.55 | 36.0 | 3.95e-01 | 99.5% | 80.1% |
| 1r0dA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.54 | 43.0 | 4.48e-01 | 81.6% | 97.4% |
| 4doyA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.54 | 32.0 | 3.49e-01 | 72.2% | 66.1% |
| 4e40A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.54 | 42.0 | 4.03e-01 | 80.7% | 84.9% |
| 6h2dS01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.54 | 39.0 | 3.84e-01 | 72.2% | 92.8% |
| 1wdzA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 43.0 | 4.25e-01 | 86.8% | 89.2% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 46.0 | 4.19e-01 | 92.5% | 81.8% |
| 1r9dA01 | 3.20.70.20 | Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › | 0.52 | 42.0 | 2.87e-01 | 84.4% | 78.4% |
| 4k7rA01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.51 | 40.0 | 3.39e-01 | 79.7% | 75.8% |
| 1tf5A04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.51 | 36.0 | 3.85e-01 | 70.3% | 100.0% |
| 6iknD01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.51 | 43.0 | 3.96e-01 | 86.8% | 84.3% |
| 4k1pE00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.51 | 40.0 | 3.44e-01 | 79.7% | 93.2% |
| 7zdtD01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.51 | 47.0 | 4.06e-01 | 100.0% | 63.8% |
| 4mt4A00 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.51 | 40.0 | 3.09e-01 | 82.1% | 88.3% |
| 3i9yA00 | 1.20.58.920 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 46.0 | 4.55e-01 | 98.1% | 99.6% |
| 3vkgA02 | 1.20.140.100 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain | 0.51 | 30.0 | 3.54e-01 | 92.0% | 83.0% |
ECOD (52)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3389635 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.74 | 67.0 | 5.57e-01 | 95.3% | 78.5% |
| 3176206 | 3615.1.1.0 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain | 0.74 | 45.0 | 4.04e-01 | 96.2% | 44.1% |
| 4135589 | 601.19.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Apolipoprotein | 0.74 | 64.0 | 5.51e-01 | 91.0% | 68.8% |
| 5071465 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.73 | 67.0 | 4.92e-01 | 96.7% | 69.3% |
| 3270023 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.69 | 62.0 | 5.86e-01 | 94.8% | 90.4% |
| 3971610 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.69 | 54.0 | 5.40e-01 | 81.1% | 85.9% |
| 4976751 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.69 | 60.0 | 4.87e-01 | 94.3% | 51.5% |
| 4667858 | 6108.1.1.1 ↗ | alpha bundles › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins › Dynamin_M,GED | 0.68 | 60.0 | 5.19e-01 | 92.9% | 70.6% |
| 3464251 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.67 | 52.0 | 5.03e-01 | 84.0% | 70.8% |
| None | — | 0.67 | 58.0 | 4.13e-01 | 91.5% | 34.2% | |
| 3880922 | 6108.1.1.1 ↗ | alpha bundles › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins › Dynamin_M,GED | 0.67 | 58.0 | 5.11e-01 | 91.0% | 78.3% |
| 3414399 | 5086.1.1.106 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › DUF725 | 0.66 | 46.0 | 5.10e-01 | 70.8% | 95.3% |
| 5072700 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.65 | 52.0 | 4.82e-01 | 82.5% | 78.9% |
| 4246487 | 5045.1.1.1 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A | 0.64 | 48.0 | 4.74e-01 | 97.2% | 72.2% |
| 3958387 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.63 | 39.0 | 4.26e-01 | 93.9% | 74.1% |
| 3709410 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.63 | 51.0 | 4.94e-01 | 83.0% | 79.6% |
| 3402327 | 3755.3.1.324 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF725 | 0.61 | 44.0 | 4.90e-01 | 94.3% | 91.2% |
| 3595254 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.61 | 49.0 | 5.01e-01 | 82.5% | 91.2% |
| 3805780 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.60 | 48.0 | 4.69e-01 | 81.6% | 83.0% |
| 3557360 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.59 | 43.0 | 3.92e-01 | 73.6% | 87.5% |
| 3737723 | 4177.1.1.5 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 | 0.59 | 48.0 | 4.86e-01 | 84.0% | 98.6% |
| 3490130 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.59 | 48.0 | 4.34e-01 | 84.0% | 79.6% |
| 3789396 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.59 | 47.0 | 4.15e-01 | 83.0% | 76.8% |
| 4999412 | 1075.5.1.8 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 | 0.58 | 39.0 | 4.09e-01 | 95.3% | 73.7% |
| 4988202 | 1075.5.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt | 0.57 | 39.0 | 3.91e-01 | 97.6% | 66.5% |
| 3493924 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.57 | 46.0 | 4.22e-01 | 84.4% | 81.5% |
| 4952079 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.56 | 36.0 | 3.80e-01 | 99.1% | 68.7% |
| 4026262 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.56 | 49.0 | 3.43e-01 | 93.4% | 84.0% |
| 4945172 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.56 | 37.0 | 3.80e-01 | 97.2% | 67.5% |
| 4999397 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.55 | 38.0 | 3.90e-01 | 97.6% | 71.5% |
| 4952396 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.55 | 39.0 | 3.82e-01 | 97.2% | 65.2% |
| 3170506 | 4177.1.1.14 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_2 | 0.55 | 44.0 | 4.26e-01 | 83.0% | 80.4% |
| 5077995 | 1075.5.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt | 0.55 | 37.0 | 3.91e-01 | 97.2% | 74.9% |
| 3924049 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.55 | 33.0 | 3.57e-01 | 84.9% | 68.6% |
| 4537363 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.54 | 48.0 | 3.35e-01 | 93.4% | 77.0% |
| 3245037 | 3755.3.1.590 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PF29149 | 0.54 | 41.0 | 4.43e-01 | 81.6% | 91.7% |
| 3506288 | 4177.1.1.6 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3_WASP_bdg | 0.54 | 43.0 | 4.31e-01 | 83.0% | 88.3% |
| 4467971 | 1189.1.1.9 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › ATG17_like | 0.54 | 40.0 | 3.74e-01 | 76.9% | 82.6% |
| 4547067 | 601.19.1.32 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › PRM1 | 0.54 | 43.0 | 4.27e-01 | 84.9% | 93.3% |
| 3212246 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.53 | 38.0 | 4.15e-01 | 85.8% | 87.4% |
| 3637309 | 4323.1.1.0 ↗ | alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C | 0.53 | 38.0 | 4.06e-01 | 95.8% | 82.1% |
| 4875585 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.53 | 37.0 | 3.09e-01 | 70.8% | 69.6% |
| 4121246 | 4177.2.1.4 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain › ATG17_like | 0.53 | 40.0 | 3.62e-01 | 77.8% | 82.5% |
| 5026838 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.52 | 47.0 | 4.47e-01 | 98.1% | 95.5% |
| 3458456 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.52 | 45.0 | 4.38e-01 | 92.9% | 99.1% |
| 3265198 | 109.4.1.496 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec5 | 0.51 | 38.0 | 2.72e-01 | 94.3% | 26.8% |
| 4997036 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.51 | 36.0 | 3.83e-01 | 71.7% | 87.0% |
| 3254587 | 1174.1.1.7 ↗ | alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › Frag1 | 0.51 | 40.0 | 4.03e-01 | 96.7% | 79.5% |
| 4996693 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.51 | 47.0 | 4.66e-01 | 97.6% | 100.0% |
| 3988926 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.51 | 45.0 | 3.88e-01 | 100.0% | 62.2% |
| 3667580 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.51 | 43.0 | 4.01e-01 | 90.1% | 86.8% |
| 4665474 | 4177.2.1.4 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain › ATG17_like | 0.50 | 43.0 | 4.08e-01 | 92.5% | 96.9% |
D2
high
residues 166-230
Domain cluster:
representative
CATH (35)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4g6dB02 | 6.10.140.1800 | Special › Helix non-globular › Helix Hairpins › | 0.75 | 43.0 | 4.00e-01 | 72.3% | 45.7% |
| 4c3eM00 | 1.20.120.1350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain | 0.70 | 55.0 | 4.13e-01 | 84.6% | 54.2% |
| 6h7bA01 | 1.10.1900.10 | Mainly Alpha › Orthogonal Bundle › c-terminal domain of poly(a) binding protein › c-terminal domain of poly(a) binding protein | 0.69 | 59.0 | 5.75e-01 | 98.5% | 89.2% |
| 2qvwC06 | 1.10.1520.10 | Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain | 0.66 | 47.0 | 3.58e-01 | 75.4% | 55.6% |
| 1xl7A01 | 1.10.275.20 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Choline/Carnitine o-acyltransferase | 0.64 | 46.0 | 3.91e-01 | 75.4% | 82.5% |
| 1qr0A01 | 3.90.470.20 | Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › 4'-phosphopantetheinyl transferase domain | 0.63 | 50.0 | 4.09e-01 | 89.2% | 52.0% |
| 3uk6A02 | 1.10.8.60 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.62 | 48.0 | 4.49e-01 | 92.3% | 67.5% |
| 4cs9B02 | 1.20.120.1350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain | 0.62 | 49.0 | 4.20e-01 | 87.7% | 100.0% |
| 4cs9C00 | 1.20.120.1350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain | 0.62 | 53.0 | 3.99e-01 | 96.9% | 68.5% |
| 1bgfA00 | 1.10.532.10 | Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain | 0.61 | 46.0 | 3.73e-01 | 80.0% | 50.0% |
| 2c9oB03 | 1.10.8.60 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.60 | 46.0 | 4.29e-01 | 93.8% | 67.5% |
| 1or7B01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.59 | 51.0 | 4.59e-01 | 100.0% | 79.8% |
| 2o7gA00 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.59 | 50.0 | 4.51e-01 | 93.8% | 80.7% |
| 1ad6A00 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.59 | 46.0 | 3.48e-01 | 90.8% | 48.6% |
| 3kbbA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.59 | 40.0 | 3.93e-01 | 70.8% | 92.9% |
| 1u6mA00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.59 | 40.0 | 2.91e-01 | 70.8% | 88.9% |
| 5yh1A01 | 3.90.1640.30 | Alpha Beta › Alpha-Beta Complex › inorganic pyrophosphatase (n-terminal core) › | 0.58 | 51.0 | 3.36e-01 | 98.5% | 85.5% |
| 1y8aA02 | 1.10.3870.10 | Mainly Alpha › Orthogonal Bundle › AF1437-like domain fold › AF1437-like domain superfamily | 0.58 | 48.0 | 4.09e-01 | 96.9% | 86.2% |
| 5svlA01 | 1.10.287.940 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › atp-gated p2x4 ion channel | 0.57 | 40.0 | 3.95e-01 | 72.3% | 76.5% |
| 1h6gA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.57 | 41.0 | 3.46e-01 | 78.5% | 75.0% |
| 3deeA01 | 1.10.150.690 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DUF2063 | 0.57 | 41.0 | 3.84e-01 | 78.5% | 83.7% |
| 3r2cA00 | 1.10.940.10 | Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like | 0.57 | 41.0 | 3.21e-01 | 76.9% | 58.7% |
| 2e6oA00 | 1.10.30.10 | Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain | 0.57 | 39.0 | 3.58e-01 | 70.8% | 69.0% |
| 2q83A02 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.56 | 48.0 | 3.31e-01 | 96.9% | 76.4% |
| 4b8cJ01 | 3.80.10.10 | Alpha Beta › Alpha-Beta Horseshoe › Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) › Ribonuclease Inhibitor | 0.56 | 43.0 | 3.19e-01 | 89.2% | 95.5% |
| 2lwdA00 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.55 | 37.0 | 3.34e-01 | 75.4% | 46.9% |
| 2jaeA03 | 1.20.1440.240 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.55 | 37.0 | 3.16e-01 | 70.8% | 44.6% |
| 1ixkA01 | 3.30.70.1170 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Sun protein; domain 3 | 0.55 | 35.0 | 3.05e-01 | 83.1% | 39.0% |
| 2ozbE02 | 1.10.246.90 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Nop domain | 0.55 | 37.0 | 3.20e-01 | 86.2% | 43.0% |
| 4uyaA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.55 | 45.0 | 3.26e-01 | 93.8% | 75.6% |
| 1ailA00 | 1.10.287.10 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding | 0.55 | 38.0 | 3.73e-01 | 73.8% | 82.9% |
| 3i1aA03 | 1.20.58.840 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 46.0 | 3.79e-01 | 96.9% | 81.9% |
| 4fe7A03 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.52 | 46.0 | 3.88e-01 | 98.5% | 99.1% |
| 4cxfA01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.51 | 41.0 | 3.83e-01 | 95.4% | 85.1% |
| 6fakA02 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.50 | 41.0 | 3.90e-01 | 95.4% | 86.4% |
ECOD (28)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3721449 | 7076.1.1.0 ↗ | 0.75 | 51.0 | 4.68e-01 | 70.8% | 98.8% | |
| 5041148 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.71 | 37.0 | 3.65e-01 | 87.7% | 45.7% |
| 4996722 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.70 | 42.0 | 3.64e-01 | 73.8% | 41.1% |
| 3661336 | 143.1.1.3 ↗ | alpha arrays › PABP domain-like › PABC(PABP) domain › PABC(PABP) domain › MLLE_2 | 0.70 | 60.0 | 5.65e-01 | 96.9% | 84.8% |
| 3456039 | 143.1.1.0 ↗ | alpha arrays › PABP domain-like › PABC(PABP) domain › PABC(PABP) domain | 0.69 | 58.0 | 5.89e-01 | 95.4% | 100.0% |
| 2644285 | 3980.1.1.1 ↗ | alpha arrays › Protein C' › Protein C' › Protein C' › Paramyxo_C | 0.68 | 46.0 | 3.84e-01 | 80.0% | 41.1% |
| 4608212 | 397.7.1.1 ↗ | few secondary structure elements › Toxic hairpin › Ribosome-inactivating protein luffin P1 › Ribosome-inactivating protein luffin P1 › Vicilin_N | 0.68 | 39.0 | 3.95e-01 | 70.8% | 58.5% |
| 3471666 | 190.1.1.1 ↗ | alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box | 0.66 | 46.0 | 4.36e-01 | 70.8% | 80.0% |
| 3517647 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.66 | 45.0 | 4.10e-01 | 72.3% | 88.9% |
| 3995898 | 301.8.1.1 ↗ | a+b three layers › Bacillus chorismate mutase-like › 4'-phosphopantetheinyl transferase › 4'-phosphopantetheinyl transferase › ACPS | 0.65 | 52.0 | 3.99e-01 | 89.2% | 68.8% |
| 5067264 | 101.1.2.21 ↗ | alpha arrays › HTH › HTH › winged helix domain › Fe_dep_repress | 0.65 | 48.0 | 4.02e-01 | 81.5% | 62.5% |
| 3676971 | 143.1.1.3 ↗ | alpha arrays › PABP domain-like › PABC(PABP) domain › PABC(PABP) domain › MLLE_2 | 0.64 | 54.0 | 5.44e-01 | 98.5% | 100.0% |
| 3231974 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.63 | 47.0 | 2.51e-01 | 80.0% | 3.7% |
| 3171901 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.62 | 49.0 | 4.31e-01 | 84.6% | 73.7% |
| 4527485 | 2484.1.1.48 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II | 0.62 | 49.0 | 3.72e-01 | 90.8% | 33.7% |
| 3971610 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.62 | 47.0 | 3.27e-01 | 83.1% | 75.5% |
| 3990640 | 148.1.3.19 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_3 | 0.62 | 49.0 | 4.67e-01 | 93.8% | 73.4% |
| 3592010 | 301.8.1.1 ↗ | a+b three layers › Bacillus chorismate mutase-like › 4'-phosphopantetheinyl transferase › 4'-phosphopantetheinyl transferase › ACPS | 0.61 | 46.0 | 3.68e-01 | 84.6% | 66.9% |
| 4434200 | 142.1.1.5 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › SRI | 0.61 | 52.0 | 4.45e-01 | 100.0% | 78.2% |
| 4995358 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.60 | 41.0 | 3.45e-01 | 72.3% | 43.8% |
| 4143289 | 101.1.3.0 ↗ | alpha arrays › HTH › HTH › tetra-helical, LuxR-like | 0.60 | 41.0 | 4.36e-01 | 73.8% | 83.6% |
| 4499256 | 101.8.1.2 ↗ | alpha arrays › HTH › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › Anticodon_2 | 0.59 | 45.0 | 3.23e-01 | 83.1% | 29.8% |
| 5048328 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.59 | 40.0 | 3.71e-01 | 70.8% | 80.0% |
| 4982047 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.57 | 44.0 | 4.32e-01 | 83.1% | 91.4% |
| 5053994 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.56 | 43.0 | 4.17e-01 | 84.6% | 93.3% |
| 5075512 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.54 | 41.0 | 3.02e-01 | 83.1% | 89.9% |
| 4092989 | 7061.1.1.0 ↗ | few secondary structure elements › VWF C8-3 module › VWF C8-3 module › VWF C8-3 module | 0.53 | 44.0 | 4.21e-01 | 92.3% | 80.0% |
| 3187132 | 386.1.1.10 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › MAT1 | 0.51 | 34.0 | 3.47e-01 | 72.3% | 98.5% |