←Back to structures

OP297545.1__UXE04750.1__SEA_SHAMBRE1_13__00013

Bact-Vir

OP297545.1__UXE04750.1__SEA_SHAMBRE1_13__00013

Identity

Accession:
OP297545 ↗
Kingdom:
phage

Quality

73.5 mean pLDDT

Taxonomy

Heunggongvirae› Uroviricota› Caudoviricetes› Bismarckvirus› Arthrobacter_phage_Shambre1

TaxID: 2927284

Cluster

View cluster (11 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 3-44
PDB
Domain cluster: rep: OQ633420.1__WEV90024.1__X__00027__D5-46
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3anwB00 1.20.58.2050 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.98 82.0 5.24e-01 100.0% 22.8%
3anwA02 3.40.5.50 Alpha Beta › 3-Layer(aba) Sandwich › Ribosomal Protein L9; domain 1 › 0.87 79.0 7.01e-01 100.0% 82.8%
5of3A00 3.90.920.10 Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › DNA primase, PRIM domain 0.87 79.0 4.58e-01 100.0% 14.1%
2e9xB01 3.40.5.50 Alpha Beta › 3-Layer(aba) Sandwich › Ribosomal Protein L9; domain 1 › 0.82 74.0 6.29e-01 100.0% 71.2%
2e9xD02 3.40.5.60 Alpha Beta › 3-Layer(aba) Sandwich › Ribosomal Protein L9; domain 1 › 0.79 67.0 6.08e-01 100.0% 88.3%
2hjqA01 3.40.5.20 Alpha Beta › 3-Layer(aba) Sandwich › Ribosomal Protein L9; domain 1 › YqbF domain 0.77 64.0 6.31e-01 100.0% 93.5%
4fsdA02 3.40.5.100 Alpha Beta › 3-Layer(aba) Sandwich › Ribosomal Protein L9; domain 1 › 0.75 62.0 5.09e-01 100.0% 59.3%
4wpzA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.69 54.0 3.10e-01 85.7% 16.3%
3pvlA05 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.68 57.0 4.79e-01 97.6% 77.6%
3g1jA00 2.30.30.350 Mainly Beta › Roll › SH3 type barrels. › mobile metagenome of vibrio cholerae. Integron cassette protein vch_cass4. 0.66 55.0 4.44e-01 100.0% 82.2%
1i07A00 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.65 47.0 4.23e-01 78.6% 57.6%
4ofqA02 2.60.40.740 Mainly Beta › Sandwich › Immunoglobulin-like › 0.61 50.0 3.46e-01 95.2% 38.1%
8jx6A02 2.30.30.780 Mainly Beta › Roll › SH3 type barrels. › 0.61 49.0 3.78e-01 92.9% 100.0%
2woyA02 2.60.40.740 Mainly Beta › Sandwich › Immunoglobulin-like › 0.61 49.0 3.43e-01 95.2% 37.3%
3nlcA01 3.30.70.2700 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 46.0 3.97e-01 92.9% 98.7%
1l5aA01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.58 47.0 3.20e-01 100.0% 85.3%
4e8uA00 3.30.70.2890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › XS domain 0.56 42.0 2.97e-01 92.9% 75.3%
4ktbA00 3.90.79.10 Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase 0.56 40.0 2.81e-01 78.6% 85.6%
1y7xA01 2.30.30.550 Mainly Beta › Roll › SH3 type barrels. › Major Vault Protein repeat 0.56 45.0 4.40e-01 100.0% 85.1%
2f2hA03 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.55 43.0 4.19e-01 92.9% 83.3%
1ul7A00 3.30.310.80 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Kinase associated domain 1, KA1 0.54 40.0 3.29e-01 92.9% 89.2%
2oycA02 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.54 40.0 2.94e-01 81.0% 79.5%
3gfoA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 42.0 2.72e-01 97.6% 64.5%
2h9fA02 3.10.310.10 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 0.53 39.0 2.65e-01 85.7% 48.1%
1l6rA01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.53 42.0 2.93e-01 92.9% 86.6%
2mlbA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.52 37.0 3.18e-01 78.6% 63.3%
7tg5A01 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.52 40.0 3.25e-01 100.0% 43.9%
1rvkA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.51 35.0 2.67e-01 73.8% 37.9%
7dd0C01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 39.0 2.55e-01 90.5% 26.2%
5m1pB00 3.30.420.240 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.50 37.0 2.54e-01 83.3% 41.3%
ECOD (81)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
144028 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.98 82.0 8.06e-01 100.0% 84.1%
4982789 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.95 89.0 7.49e-01 100.0% 70.8%
4991614 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.92 85.0 7.64e-01 100.0% 78.2%
3716713 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.92 84.0 7.88e-01 100.0% 94.0%
5028408 4076.3.1.5 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain › Gins51_C 0.91 82.0 7.72e-01 97.6% 94.0%
4358525 4076.4.1.0 ↗ a+b two layers › L9 N-domain-like › primase chain A, C-terminal domain › primase chain A, C-terminal domain 0.91 84.0 7.87e-01 100.0% 90.0%
4981952 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.91 84.0 7.85e-01 100.0% 90.0%
4978275 4076.3.1.5 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain › Gins51_C 0.91 85.0 7.60e-01 100.0% 87.3%
4927873 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.90 83.0 7.26e-01 100.0% 75.0%
5042275 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.90 82.0 7.42e-01 100.0% 87.3%
5044096 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.90 80.0 7.54e-01 97.6% 92.0%
5055750 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.90 82.0 7.69e-01 100.0% 94.0%
4935547 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.90 82.0 7.74e-01 100.0% 94.0%
4956746 4076.3.1.5 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain › Gins51_C 0.90 81.0 7.60e-01 97.6% 94.0%
4973337 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.89 82.0 7.43e-01 100.0% 85.5%
5066664 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.89 78.0 7.65e-01 97.6% 97.8%
4932084 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.89 82.0 7.67e-01 100.0% 94.0%
4939413 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.89 81.0 7.58e-01 100.0% 100.0%
5035786 4076.3.1.5 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain › Gins51_C 0.89 80.0 7.57e-01 100.0% 96.0%
4946969 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.89 80.0 7.47e-01 97.6% 94.0%
4956454 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.89 80.0 7.26e-01 100.0% 78.2%
4081421 4076.4.1.0 ↗ a+b two layers › L9 N-domain-like › primase chain A, C-terminal domain › primase chain A, C-terminal domain 0.88 80.0 7.53e-01 100.0% 94.0%
3601134 4076.1.1.0 ↗ a+b two layers › L9 N-domain-like › L9 N-domain-like › L9 N-domain-like 0.88 77.0 6.37e-01 100.0% 57.1%
4956745 4076.4.1.0 ↗ a+b two layers › L9 N-domain-like › primase chain A, C-terminal domain › primase chain A, C-terminal domain 0.88 79.0 7.44e-01 100.0% 94.0%
4025911 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.88 79.0 6.97e-01 100.0% 83.3%
5010674 4076.3.1.11 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain › PF25865 0.88 76.0 6.94e-01 100.0% 74.5%
4641420 4076.4.1.1 ↗ a+b two layers › L9 N-domain-like › primase chain A, C-terminal domain › primase chain A, C-terminal domain › PriS_C 0.88 80.0 6.08e-01 100.0% 50.0%
5069341 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.88 78.0 7.38e-01 100.0% 94.0%
1346119 4076.4.1.1 ↗ a+b two layers › L9 N-domain-like › primase chain A, C-terminal domain › primase chain A, C-terminal domain › PriS_C 0.87 79.0 7.37e-01 100.0% 88.2%
4944185 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.87 79.0 6.77e-01 100.0% 70.8%
5036241 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.87 80.0 6.79e-01 100.0% 72.3%
4269273 4076.4.1.1 ↗ a+b two layers › L9 N-domain-like › primase chain A, C-terminal domain › primase chain A, C-terminal domain › PriS_C 0.87 76.0 7.49e-01 97.6% 100.0%
3296816 4076.3.1.6 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain › GINS_N 0.86 79.0 6.90e-01 100.0% 78.3%
4025149 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.86 74.0 6.68e-01 100.0% 91.7%
3818732 4076.3.1.9 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain › PSF1_C 0.86 76.0 6.94e-01 100.0% 85.5%
5011186 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.86 76.0 6.75e-01 100.0% 76.7%
4230268 4076.4.1.0 ↗ a+b two layers › L9 N-domain-like › primase chain A, C-terminal domain › primase chain A, C-terminal domain 0.86 75.0 7.39e-01 97.6% 100.0%
4932061 4076.4.1.0 ↗ a+b two layers › L9 N-domain-like › primase chain A, C-terminal domain › primase chain A, C-terminal domain 0.84 76.0 7.44e-01 100.0% 100.0%
4967982 4076.4.1.0 ↗ a+b two layers › L9 N-domain-like › primase chain A, C-terminal domain › primase chain A, C-terminal domain 0.84 71.0 7.03e-01 95.2% 97.7%
5063665 4076.4.1.0 ↗ a+b two layers › L9 N-domain-like › primase chain A, C-terminal domain › primase chain A, C-terminal domain 0.84 76.0 7.41e-01 100.0% 97.8%
5035097 4076.4.1.0 ↗ a+b two layers › L9 N-domain-like › primase chain A, C-terminal domain › primase chain A, C-terminal domain 0.82 72.0 7.08e-01 100.0% 97.8%
3929869 4076.3.1.8 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain › PSF2_N 0.82 73.0 6.67e-01 100.0% 85.5%
4031645 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.82 71.0 6.72e-01 100.0% 96.0%
4169249 4076.4.1.0 ↗ a+b two layers › L9 N-domain-like › primase chain A, C-terminal domain › primase chain A, C-terminal domain 0.82 72.0 6.94e-01 100.0% 93.8%
5036149 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.81 72.0 7.07e-01 100.0% 100.0%
4993371 4076.4.1.0 ↗ a+b two layers › L9 N-domain-like › primase chain A, C-terminal domain › primase chain A, C-terminal domain 0.80 71.0 6.70e-01 100.0% 90.0%
5001806 4076.4.1.0 ↗ a+b two layers › L9 N-domain-like › primase chain A, C-terminal domain › primase chain A, C-terminal domain 0.80 70.0 6.75e-01 100.0% 91.7%
4419456 4076.4.1.0 ↗ a+b two layers › L9 N-domain-like › primase chain A, C-terminal domain › primase chain A, C-terminal domain 0.80 73.0 6.88e-01 100.0% 89.8%
5025099 4076.4.1.0 ↗ a+b two layers › L9 N-domain-like › primase chain A, C-terminal domain › primase chain A, C-terminal domain 0.80 70.0 6.61e-01 97.6% 88.0%
4057802 4076.4.1.0 ↗ a+b two layers › L9 N-domain-like › primase chain A, C-terminal domain › primase chain A, C-terminal domain 0.80 72.0 7.07e-01 100.0% 97.8%
4536596 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.79 70.0 6.76e-01 100.0% 93.8%
4939553 4076.4.1.0 ↗ a+b two layers › L9 N-domain-like › primase chain A, C-terminal domain › primase chain A, C-terminal domain 0.79 71.0 6.73e-01 100.0% 88.0%
4934987 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.79 69.0 6.79e-01 97.6% 95.6%
4280403 4076.4.1.0 ↗ a+b two layers › L9 N-domain-like › primase chain A, C-terminal domain › primase chain A, C-terminal domain 0.78 67.0 6.56e-01 97.6% 97.8%
4625340 149.1.1.1 ↗ alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 0.77 55.0 3.18e-01 76.2% 20.8%
5009 4076.3.1.2 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain › YqbF 0.77 64.0 6.20e-01 100.0% 87.8%
4653617 149.1.1.1 ↗ alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 0.76 54.0 3.02e-01 76.2% 15.4%
4423898 149.1.1.1 ↗ alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 0.76 54.0 3.05e-01 76.2% 16.2%
3705484 3529.1.1.1 ↗ beta sandwiches › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain › Vault 0.75 61.0 5.67e-01 100.0% 72.7%
3714918 3529.1.1.1 ↗ beta sandwiches › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain › Vault 0.72 60.0 5.60e-01 100.0% 74.5%
3593797 3529.1.1.0 ↗ beta sandwiches › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain 0.72 60.0 5.59e-01 100.0% 74.5%
3714926 3529.1.1.1 ↗ beta sandwiches › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain › Vault 0.72 60.0 5.69e-01 100.0% 80.0%
4988095 4076.3.1.0 ↗ a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.72 60.0 5.76e-01 97.6% 94.0%
3259841 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.72 60.0 5.20e-01 100.0% 91.4%
3606398 3529.1.1.1 ↗ beta sandwiches › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain › Vault 0.71 59.0 5.46e-01 100.0% 72.7%
4016039 149.1.1.1 ↗ alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 0.71 51.0 2.93e-01 78.6% 19.1%
4413367 149.1.1.1 ↗ alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 0.70 54.0 3.02e-01 83.3% 16.8%
4230278 149.1.1.1 ↗ alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 0.70 51.0 2.94e-01 78.6% 23.7%
4048813 3529.1.1.1 ↗ beta sandwiches › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain › Vault 0.70 59.0 5.51e-01 100.0% 76.4%
4567778 149.1.1.1 ↗ alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 0.69 53.0 2.95e-01 83.3% 15.3%
3600188 3529.1.1.0 ↗ beta sandwiches › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain 0.69 57.0 5.26e-01 100.0% 72.7%
3484084 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.69 57.0 4.51e-01 100.0% 60.0%
3270868 3529.1.1.1 ↗ beta sandwiches › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain › Vault 0.68 56.0 5.30e-01 100.0% 76.4%
3652018 149.1.1.1 ↗ alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 0.68 52.0 2.93e-01 85.7% 13.7%
1144827 4.1.1.79 ↗ beta barrels › SH3 › SH3 › SH3 › DUF3601 0.66 55.0 4.46e-01 100.0% 83.1%
4270390 11.1.5.42 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › Antigen_C 0.62 50.0 3.40e-01 95.2% 34.7%
3907737 149.1.1.1 ↗ alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 0.61 46.0 2.79e-01 85.7% 22.4%
4947045 2004.1.1.5 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.56 42.0 2.62e-01 83.3% 43.3%
3957225 2004.1.1.5 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.53 38.0 2.86e-01 85.7% 57.1%
4464132 275.1.1.0 ↗ a+b two layers › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase 0.52 42.0 3.86e-01 100.0% 78.3%
1145963 4012.3.1.1 ↗ a+b two layers › SSHS domain › SSHS domain in CRISPR-associated endonuclease Cas9 › SSHS domain in CRISPR-associated endonuclease Cas9 › Cas9_PI 0.51 41.0 3.27e-01 100.0% 58.0%