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OP434518.1__UYE91787.1__X__00054
Bact-VirOP434518.1__UYE91787.1__X__00054
Identity
- Accession:
- OP434518 ↗
- Kingdom:
- phage
Quality
91.8
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 14-138_189-222
Domain cluster:
rep: OQ240258.1__WEU69645.1__X__00024__D7-211
CATH (44)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1jogA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.70 | 49.0 | 5.28e-01 | 70.4% | 100.0% |
| 2lw1A00 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.69 | 33.0 | 4.46e-01 | 82.4% | 85.9% |
| 3kyiA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.68 | 45.0 | 4.93e-01 | 83.6% | 82.8% |
| 3vkgA12 | 1.10.287.2610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.67 | 37.0 | 3.35e-01 | 90.6% | 40.0% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.66 | 33.0 | 4.37e-01 | 85.5% | 85.7% |
| 2pfmA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.65 | 61.0 | 5.11e-01 | 100.0% | 89.8% |
| 7aalA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.63 | 44.0 | 3.66e-01 | 71.1% | 90.2% |
| 3k29A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.63 | 35.0 | 3.50e-01 | 91.8% | 52.2% |
| 5y06A01 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.62 | 37.0 | 3.24e-01 | 89.9% | 40.2% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.62 | 34.0 | 4.15e-01 | 89.9% | 82.4% |
| 1br0A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 33.0 | 3.81e-01 | 88.1% | 68.3% |
| 1rj1A00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.62 | 37.0 | 3.85e-01 | 81.8% | 62.8% |
| 2l81A00 | 1.20.120.830 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain | 0.61 | 53.0 | 5.13e-01 | 92.5% | 100.0% |
| 2p7vA00 | 1.20.120.1370 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulator of RNA polymerase sigma(70) subunit, domain 4 | 0.60 | 53.0 | 5.46e-01 | 100.0% | 99.3% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.60 | 39.0 | 4.44e-01 | 87.4% | 85.2% |
| 5unhA02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 54.0 | 4.54e-01 | 99.4% | 94.5% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.60 | 47.0 | 5.08e-01 | 86.8% | 98.5% |
| 3fppA03 | 6.10.140.1990 | Special › Helix non-globular › Helix Hairpins › | 0.59 | 32.0 | 4.08e-01 | 91.8% | 92.0% |
| 7rkxR01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 53.0 | 4.47e-01 | 98.1% | 93.2% |
| 3vbbE01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.59 | 42.0 | 4.82e-01 | 92.5% | 97.5% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.59 | 41.0 | 4.70e-01 | 83.0% | 100.0% |
| 6yz2A01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.59 | 41.0 | 4.54e-01 | 77.4% | 93.3% |
| 1s7bA00 | 1.10.3730.20 | Mainly Alpha › Orthogonal Bundle › ProC C-terminal domain-like fold › | 0.58 | 33.0 | 3.97e-01 | 78.6% | 82.1% |
| 3ajmB02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.58 | 41.0 | 4.43e-01 | 84.9% | 86.5% |
| 3pwxA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.58 | 48.0 | 4.59e-01 | 90.6% | 76.6% |
| 4x28C03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.57 | 41.0 | 4.31e-01 | 78.6% | 81.8% |
| 3rzeA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.57 | 51.0 | 4.30e-01 | 98.1% | 93.3% |
| 3ay5A02 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.57 | 40.0 | 3.99e-01 | 71.7% | 92.7% |
| 7f16R01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.57 | 51.0 | 4.25e-01 | 98.1% | 87.4% |
| 3m0fB02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.57 | 39.0 | 4.46e-01 | 83.6% | 91.1% |
| 6xkyA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.57 | 47.0 | 4.44e-01 | 88.1% | 82.4% |
| 4p79A00 | 1.20.140.150 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.56 | 43.0 | 4.13e-01 | 79.2% | 86.7% |
| 1g4uS01 | 1.20.120.260 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Virulence factor YopE uncharacterised domain | 0.56 | 42.0 | 4.64e-01 | 83.0% | 100.0% |
| 4jioA02 | 1.20.140.50 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › alix/aip1 like domains | 0.55 | 43.0 | 4.53e-01 | 100.0% | 90.9% |
| 1qu7A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.55 | 35.0 | 3.12e-01 | 88.7% | 44.9% |
| 2e87A01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.54 | 45.0 | 4.57e-01 | 88.1% | 98.1% |
| 2lqgA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.54 | 39.0 | 4.19e-01 | 80.5% | 87.0% |
| 2hujA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.52 | 39.0 | 4.28e-01 | 77.4% | 100.0% |
| 2ip6A00 | 1.20.1440.140 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.51 | 28.0 | 3.57e-01 | 92.5% | 94.3% |
| 4id0A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 35.0 | 4.04e-01 | 84.3% | 98.2% |
| 3behB01 | 1.20.120.540 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels | 0.51 | 35.0 | 3.90e-01 | 76.1% | 93.2% |
| 7sk7A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 44.0 | 3.80e-01 | 95.6% | 96.0% |
| 2pvqA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.50 | 33.0 | 3.95e-01 | 81.8% | 100.0% |
| 4od4A02 | 1.20.120.1780 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase | 0.50 | 36.0 | 4.02e-01 | 86.8% | 99.2% |
ECOD (52)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4977102 | 603.2.1.0 ↗ | alpha bundles › STAT-like › STAT › STAT | 0.73 | 34.0 | 3.88e-01 | 83.6% | 57.6% |
| 3893367 | 604.1.1.92 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › SR_desmoplakin_3 | 0.71 | 35.0 | 3.50e-01 | 89.3% | 44.8% |
| 3485540 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.68 | 36.0 | 3.54e-01 | 88.7% | 46.9% |
| 3200936 | 5001.1.1.85 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin | 0.68 | 63.0 | 5.47e-01 | 100.0% | 93.8% |
| 3498458 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.68 | 37.0 | 3.72e-01 | 89.9% | 51.5% |
| 3569017 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.68 | 32.0 | 3.27e-01 | 88.7% | 44.4% |
| 3632571 | 5001.1.1.85 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin | 0.66 | 61.0 | 5.08e-01 | 100.0% | 94.4% |
| 4962299 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.66 | 35.0 | 3.58e-01 | 85.5% | 51.6% |
| 3598054 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.65 | 35.0 | 3.68e-01 | 88.1% | 55.9% |
| 3312979 | 602.1.1.3 ↗ | alpha arrays › L-aspartase middle domain-like › L-aspartase middle domain-like › L-aspartase middle domain-like › Lyase_aromatic | 0.65 | 60.0 | 4.89e-01 | 100.0% | 80.3% |
| 3496310 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.65 | 34.0 | 3.97e-01 | 81.8% | 69.2% |
| 3687766 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.64 | 37.0 | 3.29e-01 | 91.2% | 40.0% |
| 3205388 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.63 | 35.0 | 3.08e-01 | 88.7% | 35.7% |
| 4165476 | 2004.1.1.799 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_27, AAA_29 | 0.63 | 36.0 | 2.57e-01 | 88.1% | 18.9% |
| 3429223 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.63 | 38.0 | 3.98e-01 | 82.4% | 64.0% |
| 1877523 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.63 | 35.0 | 4.16e-01 | 81.8% | 78.6% |
| 3215426 | 192.29.1.172 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF29678 | 0.62 | 49.0 | 5.33e-01 | 81.1% | 99.2% |
| 3655677 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.62 | 33.0 | 3.15e-01 | 88.7% | 41.6% |
| 2168148 | 601.7.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like | 0.62 | 50.0 | 5.40e-01 | 85.5% | 100.0% |
| 3172715 | 5001.1.1.39 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › RTA1 | 0.62 | 51.0 | 4.45e-01 | 88.7% | 95.5% |
| 3554055 | 3567.1.1.12 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › CD47 | 0.62 | 53.0 | 5.26e-01 | 98.1% | 88.2% |
| 3586523 | 604.12.1.45 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › PPP1R21_helical | 0.61 | 45.0 | 4.41e-01 | 78.6% | 70.3% |
| 3912710 | 5001.1.1.8 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HlyIII | 0.60 | 55.0 | 4.62e-01 | 99.4% | 77.8% |
| 2492086 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.60 | 48.0 | 5.02e-01 | 84.9% | 100.0% |
| 3547040 | 376.1.3.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger | 0.60 | 36.0 | 3.56e-01 | 88.7% | 55.3% |
| 3790952 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.59 | 48.0 | 5.06e-01 | 88.1% | 98.6% |
| 3337031 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.59 | 33.0 | 3.16e-01 | 88.7% | 46.1% |
| 3502265 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.58 | 45.0 | 4.26e-01 | 100.0% | 68.6% |
| 3396400 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.58 | 33.0 | 3.74e-01 | 78.6% | 72.0% |
| 4967893 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.58 | 52.0 | 4.54e-01 | 96.9% | 77.3% |
| 3288619 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.58 | 48.0 | 4.28e-01 | 89.3% | 68.3% |
| 3933806 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.57 | 38.0 | 4.11e-01 | 79.9% | 80.0% |
| 3524429 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.56 | 32.0 | 4.01e-01 | 74.2% | 90.0% |
| 3246395 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.56 | 44.0 | 4.05e-01 | 81.8% | 95.1% |
| 3473984 | 603.1.1.97 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE | 0.55 | 45.0 | 3.83e-01 | 85.5% | 79.6% |
| 4022513 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.55 | 42.0 | 4.23e-01 | 78.6% | 91.9% |
| 3616967 | 603.1.1.97 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE | 0.55 | 45.0 | 3.85e-01 | 86.8% | 82.0% |
| 3502594 | 603.1.1.98 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE, Syntaxin_2 | 0.55 | 45.0 | 3.97e-01 | 84.9% | 84.1% |
| 3354508 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.55 | 42.0 | 4.07e-01 | 79.9% | 81.1% |
| 3261432 | 603.1.1.17 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE | 0.55 | 45.0 | 4.07e-01 | 86.8% | 94.9% |
| 3215358 | 603.1.1.98 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE, Syntaxin_2 | 0.54 | 43.0 | 3.96e-01 | 82.4% | 91.5% |
| 3251611 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.54 | 44.0 | 3.87e-01 | 84.3% | 87.7% |
| 3927056 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.54 | 44.0 | 3.97e-01 | 85.5% | 94.8% |
| 4986986 | 3633.1.1.0 ↗ | alpha duplicates or obligate multimers › Haptoglobin-hemoglobin receptor › Haptoglobin-hemoglobin receptor › Haptoglobin-hemoglobin receptor | 0.54 | 36.0 | 3.27e-01 | 88.1% | 52.7% |
| 3761039 | 603.1.1.97 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE | 0.53 | 44.0 | 3.81e-01 | 87.4% | 85.7% |
| 3692131 | 5001.1.1.39 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › RTA1 | 0.53 | 46.0 | 3.86e-01 | 95.0% | 83.6% |
| 3982462 | 4132.1.1.1 ↗ | alpha bundles › IpaD-like › IpaD-like › IpaD-like › T3SS_TC | 0.53 | 48.0 | 3.92e-01 | 100.0% | 83.7% |
| 3276574 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.53 | 41.0 | 3.69e-01 | 81.1% | 88.6% |
| 3415238 | 603.1.1.6 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 | 0.53 | 41.0 | 3.93e-01 | 81.8% | 100.0% |
| 3565220 | 633.23.1.22 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL | 0.53 | 40.0 | 4.22e-01 | 82.4% | 86.2% |
| 3849331 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.52 | 33.0 | 3.82e-01 | 70.4% | 87.8% |
| 3601151 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.51 | 39.0 | 3.87e-01 | 79.9% | 97.6% |
D2
medium
residues 139-188
Domain cluster:
representative
CATH (49)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1jsgA00 | 2.40.15.10 | Mainly Beta › Beta Barrel › Proto-oncogene - Oncogene Product P14tcl1 › TCL1/MTCP1 | 0.69 | 59.0 | 4.57e-01 | 96.0% | 82.9% |
| 7vpjA01 | 3.40.50.1000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like | 0.62 | 53.0 | 3.63e-01 | 100.0% | 44.9% |
| 1gd5A00 | 3.30.1520.10 | Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain | 0.62 | 44.0 | 3.35e-01 | 78.0% | 31.5% |
| 4id2A00 | 2.40.128.510 | Mainly Beta › Beta Barrel › Lipocalin › Protein of unknown function DUF4738 | 0.61 | 50.0 | 3.84e-01 | 100.0% | 71.3% |
| 3oyyA01 | 2.30.30.30 | Mainly Beta › Roll › SH3 type barrels. › | 0.61 | 52.0 | 4.83e-01 | 100.0% | 80.3% |
| 1h6hA00 | 3.30.1520.10 | Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain | 0.61 | 44.0 | 3.22e-01 | 78.0% | 28.7% |
| 3n4eA01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.61 | 41.0 | 3.30e-01 | 76.0% | 34.6% |
| 4b6mB00 | 2.30.30.190 | Mainly Beta › Roll › SH3 type barrels. › CAP Gly-rich-like domain | 0.60 | 48.0 | 4.35e-01 | 98.0% | 84.8% |
| 7tzoA01 | 1.10.1070.11 | Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › Phosphatidylinositol 3-/4-kinase, catalytic domain | 0.60 | 50.0 | 3.55e-01 | 100.0% | 98.9% |
| 7bwcA01 | 2.115.10.20 | Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 | 0.60 | 50.0 | 3.14e-01 | 100.0% | 25.1% |
| 3u4zA00 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.60 | 44.0 | 3.44e-01 | 80.0% | 45.0% |
| 3m9qA01 | 2.30.30.140 | Mainly Beta › Roll › SH3 type barrels. › | 0.60 | 48.0 | 4.41e-01 | 98.0% | 86.1% |
| 3fm8D03 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.59 | 45.0 | 3.54e-01 | 100.0% | 38.9% |
| 3a76A01 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.58 | 48.0 | 3.64e-01 | 100.0% | 70.5% |
| 4ii1A02 | 2.30.30.140 | Mainly Beta › Roll › SH3 type barrels. › | 0.58 | 47.0 | 4.65e-01 | 98.0% | 85.7% |
| 3a5zB01 | 2.30.30.30 | Mainly Beta › Roll › SH3 type barrels. › | 0.57 | 45.0 | 4.34e-01 | 100.0% | 84.1% |
| 2nlkA02 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.57 | 50.0 | 3.15e-01 | 100.0% | 20.0% |
| 1uebA01 | 2.30.30.30 | Mainly Beta › Roll › SH3 type barrels. › | 0.57 | 48.0 | 4.51e-01 | 100.0% | 82.5% |
| 2y23A01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.56 | 41.0 | 3.25e-01 | 78.0% | 55.8% |
| 4gl6A01 | 3.10.450.570 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Domain of unknown function (DUF5037), N-terminal subdomain | 0.56 | 47.0 | 4.12e-01 | 100.0% | 65.9% |
| 3tdgA01 | 3.10.450.520 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.56 | 45.0 | 4.29e-01 | 100.0% | 75.8% |
| 6s8zA01 | 2.30.30.30 | Mainly Beta › Roll › SH3 type barrels. › | 0.56 | 44.0 | 4.24e-01 | 100.0% | 85.5% |
| 6ipaA00 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.55 | 38.0 | 2.82e-01 | 80.0% | 23.6% |
| 6xmtA02 | 3.40.1110.10 | Alpha Beta › 3-Layer(aba) Sandwich › Calcium-transporting ATPase, cytoplasmic domain N › Calcium-transporting ATPase, cytoplasmic domain N | 0.55 | 46.0 | 3.31e-01 | 100.0% | 43.5% |
| 4iupA02 | 2.30.30.140 | Mainly Beta › Roll › SH3 type barrels. › | 0.55 | 44.0 | 4.06e-01 | 98.0% | 81.9% |
| 6secA03 | 2.70.98.10 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › | 0.55 | 46.0 | 2.95e-01 | 100.0% | 31.3% |
| 3sjnA01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.54 | 38.0 | 2.99e-01 | 76.0% | 37.8% |
| 7bspA01 | 2.70.150.10 | Mainly Beta › Distorted Sandwich › Calcium-transporting ATPase, cytoplasmic transduction domain A › Calcium-transporting ATPase, cytoplasmic transduction domain A | 0.54 | 44.0 | 3.25e-01 | 96.0% | 66.4% |
| 4hj1B03 | 2.60.40.3770 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.54 | 39.0 | 3.34e-01 | 80.0% | 70.0% |
| 3k7cA00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.54 | 44.0 | 3.61e-01 | 100.0% | 88.0% |
| 2w20B01 | 2.120.10.10 | Mainly Beta › 6 Propeller › Neuraminidase › | 0.54 | 44.0 | 2.71e-01 | 100.0% | 19.0% |
| 2iw3A05 | 2.40.50.990 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.54 | 43.0 | 3.55e-01 | 100.0% | 67.9% |
| 6krwA01 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.54 | 42.0 | 2.72e-01 | 100.0% | 16.2% |
| 4ak1A02 | 2.30.30.1270 | Mainly Beta › Roll › SH3 type barrels. › | 0.54 | 39.0 | 3.74e-01 | 84.0% | 76.6% |
| 4r1kB00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.54 | 43.0 | 3.36e-01 | 100.0% | 76.5% |
| 5cflA02 | 3.40.50.12100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Stimulator of interferon genes protein | 0.54 | 44.0 | 3.28e-01 | 98.0% | 40.1% |
| 3ef8A00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.54 | 44.0 | 3.28e-01 | 100.0% | 61.5% |
| 5ighA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.53 | 42.0 | 3.70e-01 | 100.0% | 55.7% |
| 2oc3A00 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.53 | 39.0 | 2.63e-01 | 100.0% | 16.8% |
| 1lyvA00 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.53 | 40.0 | 2.61e-01 | 92.0% | 18.0% |
| 2czoA00 | 3.30.1520.10 | Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain | 0.52 | 37.0 | 2.89e-01 | 80.0% | 32.3% |
| 1f0cA02 | 2.30.39.10 | Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 | 0.52 | 37.0 | 2.98e-01 | 82.0% | 84.7% |
| 3b77A01 | 2.30.29.50 | Mainly Beta › Roll › PH-domain like › Bacterial Pleckstrin homology domain | 0.52 | 38.0 | 3.20e-01 | 86.0% | 57.0% |
| 3s5wA00 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.51 | 40.0 | 2.47e-01 | 100.0% | 98.8% |
| 2vb6A01 | 2.30.30.360 | Mainly Beta › Roll › SH3 type barrels. › Myosin S1 fragment, N-terminal | 0.51 | 36.0 | 3.57e-01 | 90.0% | 74.1% |
| 3f4lA02 | 3.30.360.10 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 | 0.50 | 41.0 | 2.80e-01 | 100.0% | 75.3% |
| 8djfA01 | 2.120.10.30 | Mainly Beta › 6 Propeller › Neuraminidase › TolB, C-terminal domain | 0.50 | 40.0 | 2.61e-01 | 100.0% | 25.2% |
| 3bm4A00 | 3.90.79.10 | Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase | 0.50 | 37.0 | 2.56e-01 | 82.0% | 60.4% |
| 5c7qB00 | 3.90.79.10 | Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase | 0.50 | 34.0 | 2.52e-01 | 78.0% | 22.2% |
ECOD (64)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4413603 | 218.1.1.8 ↗ | a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA | 0.67 | 46.0 | 3.68e-01 | 82.0% | 36.0% |
| 4889666 | 11.2.1.117 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › PI-PLC-Y | 0.67 | 49.0 | 3.84e-01 | 82.0% | 34.7% |
| 4210722 | 218.1.1.8 ↗ | a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA | 0.66 | 45.0 | 3.63e-01 | 82.0% | 36.0% |
| 3726757 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.66 | 56.0 | 3.46e-01 | 100.0% | 18.4% |
| 3243901 | 2007.2.3.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase | 0.65 | 55.0 | 3.43e-01 | 100.0% | 15.8% |
| 3583039 | 220.1.1.1 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH | 0.65 | 53.0 | 3.99e-01 | 96.0% | 68.9% |
| 4049598 | 218.1.1.8 ↗ | a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA | 0.65 | 44.0 | 3.60e-01 | 82.0% | 36.0% |
| 3991944 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.65 | 56.0 | 3.53e-01 | 100.0% | 19.3% |
| 3923085 | 2007.2.3.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase | 0.64 | 53.0 | 3.34e-01 | 100.0% | 16.0% |
| 4606142 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.64 | 55.0 | 3.13e-01 | 100.0% | 17.2% |
| 3924294 | 2007.2.3.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase | 0.64 | 55.0 | 3.40e-01 | 100.0% | 16.7% |
| 3581460 | 2007.2.3.21 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase, PTP-SAK | 0.63 | 54.0 | 3.36e-01 | 100.0% | 16.4% |
| 3303879 | 331.3.1.43 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › PDF2_C | 0.63 | 51.0 | 3.29e-01 | 92.0% | 22.1% |
| 3770804 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.63 | 51.0 | 4.48e-01 | 100.0% | 84.7% |
| 3799750 | 2007.2.3.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase | 0.62 | 52.0 | 3.58e-01 | 100.0% | 25.5% |
| 3738581 | 2007.2.3.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase | 0.62 | 53.0 | 3.34e-01 | 100.0% | 17.4% |
| 3936087 | 2007.2.3.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase | 0.62 | 52.0 | 3.22e-01 | 100.0% | 14.8% |
| 3579141 | 2007.2.3.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase | 0.62 | 52.0 | 3.25e-01 | 100.0% | 16.5% |
| 3923528 | 2007.2.3.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase | 0.62 | 53.0 | 3.29e-01 | 100.0% | 16.9% |
| 4468322 | 218.1.1.8 ↗ | a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA | 0.61 | 40.0 | 3.26e-01 | 76.0% | 34.0% |
| 4104219 | 4.1.1.57 ↗ | beta barrels › SH3 › SH3 › SH3 › EFP_N | 0.61 | 50.0 | 4.74e-01 | 100.0% | 84.6% |
| 3232470 | 2007.2.3.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase | 0.61 | 52.0 | 3.23e-01 | 100.0% | 16.2% |
| 4066174 | 218.1.1.8 ↗ | a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA | 0.61 | 41.0 | 3.33e-01 | 80.0% | 34.3% |
| 3649440 | 3946.1.1.1 ↗ | beta duplicates or obligate multimers › Pleurotolysin B C-terminal domain › Pleurotolysin B C-terminal domain › Pleurotolysin B C-terminal domain › Vps62 | 0.60 | 43.0 | 2.96e-01 | 76.0% | 21.1% |
| 4146937 | 4.1.1.57 ↗ | beta barrels › SH3 › SH3 › SH3 › EFP_N | 0.60 | 50.0 | 4.71e-01 | 100.0% | 81.5% |
| 3393084 | 4.8.1.0 ↗ | beta barrels › SH3 › Chromo domain-like › Chromo domain-like | 0.60 | 49.0 | 4.34e-01 | 96.0% | 70.0% |
| 4121823 | 206.1.1.11 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH | 0.60 | 51.0 | 2.96e-01 | 100.0% | 17.9% |
| 4548716 | 218.1.1.8 ↗ | a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA | 0.60 | 40.0 | 3.31e-01 | 80.0% | 36.0% |
| 3376518 | 331.3.1.43 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › PDF2_C | 0.59 | 48.0 | 3.11e-01 | 92.0% | 22.0% |
| 3709896 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.58 | 47.0 | 4.17e-01 | 100.0% | 67.1% |
| 3281018 | 330.2.1.0 ↗ | a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) | 0.58 | 47.0 | 3.96e-01 | 100.0% | 65.0% |
| 4643742 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.58 | 47.0 | 4.11e-01 | 98.0% | 81.2% |
| 3822349 | 331.3.1.43 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › PDF2_C | 0.58 | 49.0 | 3.24e-01 | 100.0% | 24.7% |
| 3985126 | 520.1.1.0 ↗ | beta sandwiches › gp9 N-terminal domain-like › gp9 N-terminal domain-related › gp9 N-terminal domain-related | 0.58 | 46.0 | 4.07e-01 | 94.0% | 75.0% |
| 4041586 | 4.1.1.57 ↗ | beta barrels › SH3 › SH3 › SH3 › EFP_N | 0.58 | 45.0 | 4.35e-01 | 100.0% | 81.5% |
| 4314572 | 218.1.1.8 ↗ | a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA | 0.57 | 39.0 | 3.24e-01 | 78.0% | 37.0% |
| 4101580 | 4.1.1.57 ↗ | beta barrels › SH3 › SH3 › SH3 › EFP_N | 0.57 | 45.0 | 4.33e-01 | 100.0% | 81.5% |
| 3808409 | 331.3.1.43 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › PDF2_C | 0.57 | 45.0 | 2.97e-01 | 92.0% | 20.4% |
| 3214741 | 243.1.1.0 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like | 0.57 | 48.0 | 4.08e-01 | 100.0% | 93.3% |
| 3599172 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.57 | 45.0 | 4.28e-01 | 100.0% | 81.5% |
| 4213539 | 4.1.1.57 ↗ | beta barrels › SH3 › SH3 › SH3 › EFP_N | 0.56 | 45.0 | 4.27e-01 | 100.0% | 81.5% |
| 3432658 | 330.1.1.1 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm | 0.56 | 41.0 | 3.42e-01 | 80.0% | 55.8% |
| 4201878 | 4.1.1.57 ↗ | beta barrels › SH3 › SH3 › SH3 › EFP_N | 0.56 | 45.0 | 4.26e-01 | 100.0% | 81.5% |
| 3710638 | 881.1.1.0 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like | 0.56 | 46.0 | 3.32e-01 | 100.0% | 33.1% |
| 4433785 | 283.2.1.4 ↗ | a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like › GP46 | 0.56 | 45.0 | 3.48e-01 | 96.0% | 40.0% |
| 3306779 | 4.1.1.57 ↗ | beta barrels › SH3 › SH3 › SH3 › EFP_N | 0.56 | 47.0 | 4.36e-01 | 100.0% | 80.0% |
| 3584039 | 5.1.5.89 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › PF31099 | 0.55 | 44.0 | 2.73e-01 | 100.0% | 20.8% |
| 3960836 | 267.1.1.0 ↗ | a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain | 0.55 | 47.0 | 3.17e-01 | 100.0% | 33.8% |
| 3265170 | 4.1.1.57 ↗ | beta barrels › SH3 › SH3 › SH3 › EFP_N | 0.54 | 45.0 | 4.20e-01 | 100.0% | 80.0% |
| 4037383 | 4.1.1.57 ↗ | beta barrels › SH3 › SH3 › SH3 › EFP_N | 0.54 | 42.0 | 4.05e-01 | 100.0% | 80.0% |
| 3689299 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.54 | 44.0 | 3.54e-01 | 98.0% | 48.2% |
| 3988584 | 2.4.1.2 ↗ | beta barrels › OB-fold › MOP-like › MOP-like › TOBE_2 | 0.53 | 38.0 | 3.17e-01 | 80.0% | 66.0% |
| 4051625 | 4.1.1.57 ↗ | beta barrels › SH3 › SH3 › SH3 › EFP_N | 0.53 | 42.0 | 4.05e-01 | 100.0% | 81.5% |
| 3174327 | 4.1.1.41 ↗ | beta barrels › SH3 › SH3 › SH3 › NOT2_3_5_C | 0.53 | 41.0 | 2.88e-01 | 90.0% | 27.2% |
| 4938125 | 896.1.1.0 ↗ | a+b two layers › SRP9/14-like › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Signal recognition particle alu RNA binding heterodimer SRP9/14-related | 0.53 | 39.0 | 3.44e-01 | 86.0% | 58.8% |
| 3994731 | 267.1.1.3 ↗ | a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase | 0.52 | 43.0 | 3.07e-01 | 100.0% | 48.3% |
| 4086925 | 4.1.1.57 ↗ | beta barrels › SH3 › SH3 › SH3 › EFP_N | 0.52 | 40.0 | 3.83e-01 | 98.0% | 80.0% |
| 4507137 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.51 | 41.0 | 2.44e-01 | 100.0% | 11.7% |
| 3963585 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.51 | 37.0 | 3.06e-01 | 82.0% | 46.7% |
| 3693934 | 73.1.1.1 ↗ | beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › FHA | 0.51 | 41.0 | 3.24e-01 | 100.0% | 83.8% |
| 4963204 | 221.4.1.1 ↗ | a+b two layers › beta-Grasp › Nudix › Nudix › NUDIX | 0.51 | 42.0 | 2.97e-01 | 100.0% | 28.1% |
| 4991059 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.51 | 42.0 | 4.24e-01 | 100.0% | 98.0% |
| 3238801 | 2484.1.1.200 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › FTH | 0.51 | 40.0 | 2.43e-01 | 96.0% | 11.9% |
| 4232558 | 218.1.1.8 ↗ | a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA | 0.51 | 33.0 | 2.87e-01 | 78.0% | 35.0% |
D3
medium
residues 227-305
Domain cluster:
representative
CATH (27)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2fjcB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.76 | 55.0 | 4.37e-01 | 75.9% | 82.7% |
| 3m7gA02 | 1.10.8.1010 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.75 | 62.0 | 5.80e-01 | 87.3% | 85.3% |
| 4xvxA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.74 | 59.0 | 4.80e-01 | 86.1% | 58.5% |
| 1tjlA00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.74 | 52.0 | 4.26e-01 | 73.4% | 69.0% |
| 2clbA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.73 | 53.0 | 4.19e-01 | 75.9% | 81.8% |
| 2zxqA06 | 1.20.1270.70 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle | 0.72 | 53.0 | 5.69e-01 | 89.9% | 93.9% |
| 1e1dA02 | 1.20.1270.20 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.72 | 55.0 | 5.46e-01 | 86.1% | 78.6% |
| 2etdA00 | 1.20.1440.20 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain | 0.71 | 53.0 | 4.37e-01 | 83.5% | 44.0% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.71 | 56.0 | 4.53e-01 | 86.1% | 54.9% |
| 4heoA00 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.71 | 44.0 | 5.14e-01 | 86.1% | 90.9% |
| 3frrA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.70 | 50.0 | 3.78e-01 | 74.7% | 73.1% |
| 2qkwA00 | 1.20.1270.140 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AvrPto | 0.69 | 56.0 | 5.19e-01 | 88.6% | 86.1% |
| 3vbbE01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.65 | 51.0 | 4.51e-01 | 86.1% | 100.0% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.64 | 54.0 | 4.94e-01 | 94.9% | 86.1% |
| 2rdcA00 | 1.10.287.800 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 | 0.63 | 52.0 | 4.40e-01 | 91.1% | 64.7% |
| 3bbzA00 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.61 | 36.0 | 4.34e-01 | 94.9% | 93.8% |
| 5b00A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.61 | 52.0 | 3.71e-01 | 100.0% | 44.1% |
| 3b0xA01 | 1.10.150.110 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DNA polymerase beta, N-terminal domain-like | 0.59 | 46.0 | 4.52e-01 | 84.8% | 95.4% |
| 1c3cA03 | 1.10.40.30 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) | 0.59 | 40.0 | 4.00e-01 | 83.5% | 69.1% |
| 1xqoA02 | 1.10.340.30 | Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Hypothetical protein; domain 2 | 0.54 | 41.0 | 3.52e-01 | 97.5% | 48.9% |
| 2q0tB01 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.53 | 47.0 | 3.23e-01 | 93.7% | 78.5% |
| 1w36C06 | 1.10.10.990 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.53 | 34.0 | 3.56e-01 | 82.3% | 70.8% |
| 3nhiA01 | 1.10.238.20 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain | 0.53 | 42.0 | 3.54e-01 | 91.1% | 91.3% |
| 1w36B04 | 1.10.486.10 | Mainly Alpha › Orthogonal Bundle › PCRA; domain 4 › PCRA; domain 4 | 0.53 | 40.0 | 3.34e-01 | 82.3% | 45.2% |
| 1kf6D00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.52 | 43.0 | 3.80e-01 | 92.4% | 88.2% |
| 1x4oA00 | 1.10.10.790 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Surp module | 0.52 | 36.0 | 3.68e-01 | 83.5% | 74.4% |
| 1kyqA03 | 1.10.3280.10 | Mainly Alpha › Orthogonal Bundle › Siro heme synthase C-terminal domain-like › Siroheme synthase; domain 3 | 0.51 | 41.0 | 4.07e-01 | 96.2% | 84.5% |
ECOD (17)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4494025 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.79 | 65.0 | 5.87e-01 | 87.3% | 82.9% |
| 4602904 | 6091.1.1.0 ↗ | alpha bundles › Helical bundle domain in Endo-alpha-N-acetylgalactosaminidase › Helical bundle domain in Endo-alpha-N-acetylgalactosaminidase › Helical bundle domain in Endo-alpha-N-acetylgalactosaminidase | 0.79 | 63.0 | 6.16e-01 | 86.1% | 80.0% |
| 3422310 | 150.1.1.87 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Erg28 | 0.74 | 56.0 | 4.71e-01 | 81.0% | 59.0% |
| 1518845 | 601.41.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › C-terminal domain in uncharacterized DUF3829-like protein › C-terminal domain in uncharacterized DUF3829-like protein › DUF3829_2nd | 0.73 | 53.0 | 4.79e-01 | 75.9% | 68.2% |
| 5059230 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.71 | 60.0 | 4.59e-01 | 94.9% | 54.3% |
| 3220614 | 632.21.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Helical bundle domain in endo-beta-N-acetylglucosaminidase F2 › Helical bundle domain in endo-beta-N-acetylglucosaminidase F2 | 0.71 | 58.0 | 5.79e-01 | 94.9% | 87.5% |
| 3740688 | 7076.1.1.0 ↗ | 0.70 | 53.0 | 5.41e-01 | 87.3% | 85.3% | |
| 3948731 | 192.10.1.1 ↗ | alpha bundles › Long alpha-hairpin › DnaK suppressor protein DksA, alpha-hairpin domain › DnaK suppressor protein DksA, alpha-hairpin domain › DksA_N | 0.70 | 51.0 | 4.41e-01 | 75.9% | 81.7% |
| 5068844 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.70 | 55.0 | 5.25e-01 | 87.3% | 77.9% |
| 3222373 | 605.4.1.18 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › PF29357 | 0.69 | 54.0 | 5.37e-01 | 87.3% | 88.2% |
| 5022485 | 7531.1.1.1 ↗ | a/b three-layered sandwiches › Carbamate kinase-like › Carbamate kinase-like › Carbamate kinase-like › AA_kinase | 0.68 | 60.0 | 4.13e-01 | 100.0% | 45.3% |
| 3614181 | 1189.1.1.2 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG_B | 0.66 | 48.0 | 3.08e-01 | 75.9% | 88.6% |
| 3584217 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.65 | 52.0 | 4.60e-01 | 87.3% | 69.6% |
| 3571472 | 101.1.9.132 ↗ | alpha arrays › HTH › HTH › Putative DNA-binding domain › LRRC37AB_C | 0.65 | 48.0 | 5.08e-01 | 83.5% | 90.0% |
| 3600611 | 1128.1.1.0 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein | 0.62 | 55.0 | 5.11e-01 | 98.7% | 83.0% |
| 3249720 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.61 | 49.0 | 4.23e-01 | 89.9% | 85.4% |
| 3651135 | 3788.1.1.20 ↗ | alpha bundles › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) › VIN3_C | 0.60 | 46.0 | 4.71e-01 | 96.2% | 88.0% |
D4
medium
residues 306-379
Domain cluster:
representative
CATH (7)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7xcnM01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.68 | 40.0 | 3.96e-01 | 91.9% | 55.1% |
| 2gsvA00 | 6.10.140.40 | Special › Helix non-globular › Helix Hairpins › | 0.60 | 33.0 | 3.52e-01 | 85.1% | 61.2% |
| 2hxiB02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 42.0 | 3.59e-01 | 82.4% | 94.8% |
| 2rfbA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.55 | 45.0 | 2.96e-01 | 91.9% | 27.5% |
| 4l7mA00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.55 | 39.0 | 2.72e-01 | 77.0% | 56.7% |
| 3cz6A01 | 1.20.120.1480 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.52 | 43.0 | 3.98e-01 | 98.6% | 92.3% |
| 4iejA00 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.50 | 43.0 | 4.28e-01 | 94.6% | 98.7% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3802150 | 109.4.1.1262 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_long | 0.70 | 52.0 | 3.69e-01 | 81.1% | 25.1% |
| 4029493 | 526.1.1.1 ↗ | alpha bundles › ERO1-like › ERO1-like › ERO1-like › ERO1 | 0.57 | 44.0 | 2.89e-01 | 86.5% | 91.5% |
| 3562094 | 6013.1.1.0 ↗ | alpha arrays › C-terminal domains of CstF-64 › C-terminal domains of CstF-64 › C-terminal domains of CstF-64 | 0.56 | 41.0 | 3.81e-01 | 100.0% | 62.2% |
| 3782318 | 109.21.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nup96 | 0.54 | 41.0 | 2.55e-01 | 86.5% | 39.0% |
| 3615712 | 622.1.1.0 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain | 0.53 | 37.0 | 3.53e-01 | 75.7% | 83.2% |