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OP596613.1__WAX24364.1__X__00051

Bact-Vir

OP596613.1__WAX24364.1__X__00051

Identity

Accession:
OP596613 ↗
Kingdom:
phage

Quality

92.2 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 4-171
PDB
CATH (73)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4c7oA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.76 72.0 6.85e-01 100.0% 90.7%
2px0A02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.76 72.0 6.98e-01 100.0% 91.9%
5l3qA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.75 70.0 6.54e-01 100.0% 84.5%
5l3sB02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.74 70.0 6.43e-01 100.0% 82.9%
3io3A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.74 70.0 6.23e-01 100.0% 77.8%
1zu4A02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.74 69.0 6.28e-01 100.0% 84.9%
3geeA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.71 46.0 5.20e-01 100.0% 82.7%
4xc7B01 3.40.50.280 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cobalamin-binding domain 0.68 46.0 5.00e-01 100.0% 80.6%
1xfkA00 3.40.800.10 Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Ureohydrolase domain 0.67 53.0 4.22e-01 82.1% 54.6%
3vbcA00 3.40.50.11530 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.67 47.0 5.15e-01 97.6% 88.2%
5kcnA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.67 40.0 5.00e-01 97.0% 100.0%
4j1qA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.65 59.0 4.41e-01 98.2% 55.2%
3sxpA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.65 59.0 5.52e-01 98.2% 99.5%
3dmyA02 3.40.50.261 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Succinyl-CoA synthetase domains 0.64 43.0 4.64e-01 100.0% 80.7%
3vu9B00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 51.0 4.91e-01 85.1% 98.4%
4a8jA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 57.0 4.86e-01 100.0% 82.7%
1gteB05 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.63 53.0 4.37e-01 90.5% 85.9%
3cz8A01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.63 52.0 4.61e-01 88.7% 76.7%
3dcpA00 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.62 52.0 4.41e-01 88.7% 95.3%
4ncbA05 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.61 40.0 4.23e-01 98.2% 73.5%
4f2gA02 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.61 44.0 4.71e-01 98.2% 86.6%
3hcwA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.61 48.0 5.17e-01 91.7% 96.5%
3n0xA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.61 52.0 5.30e-01 94.0% 93.3%
4mcjG00 3.40.50.450 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.61 44.0 4.62e-01 100.0% 81.2%
7pt4A01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.60 52.0 5.01e-01 92.9% 89.7%
2ihtA03 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.60 52.0 4.79e-01 92.3% 83.2%
6denA03 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.60 52.0 4.69e-01 92.9% 77.2%
1ni4A00 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.60 52.0 4.07e-01 94.6% 63.0%
2xblD00 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.59 45.0 4.33e-01 100.0% 68.2%
3cjpA00 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.59 50.0 4.33e-01 90.5% 76.3%
6cblD01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.59 48.0 4.40e-01 85.7% 79.3%
7fc0E01 3.20.20.150 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes 0.59 49.0 4.30e-01 90.5% 92.3%
4ff5A00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.59 48.0 4.40e-01 88.7% 78.4%
1q6zA03 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.58 51.0 4.93e-01 92.9% 93.5%
3brsA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.58 44.0 4.82e-01 92.3% 99.3%
1poxA03 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.58 50.0 4.82e-01 92.3% 91.6%
4fe7A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.58 46.0 4.89e-01 91.7% 96.6%
2uz1A03 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.57 50.0 4.80e-01 92.9% 91.7%
4k9qA03 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.57 50.0 4.78e-01 92.9% 90.7%
1shuX00 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.57 50.0 4.87e-01 100.0% 87.3%
5ahkA03 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.57 50.0 4.81e-01 92.9% 93.6%
2vbiA03 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.57 49.0 4.77e-01 92.3% 90.5%
6snkA01 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.57 51.0 4.94e-01 100.0% 89.1%
2yvaA00 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.57 45.0 4.34e-01 99.4% 73.1%
1qv9A01 3.40.50.10830 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD) 0.56 47.0 4.93e-01 97.6% 97.4%
4pscA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.56 48.0 4.44e-01 99.4% 70.5%
4ywrA00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.56 51.0 4.64e-01 99.4% 85.5%
1ovmA03 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.56 48.0 4.68e-01 92.3% 90.4%
4rxtA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.55 46.0 4.72e-01 88.7% 100.0%
3jx9A00 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.55 38.0 3.80e-01 80.4% 68.0%
4ry8C02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.55 47.0 4.80e-01 92.9% 97.6%
3m9wA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.55 45.0 4.64e-01 88.7% 100.0%
1gkpA02 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.55 50.0 3.89e-01 97.6% 96.9%
4exbB00 3.20.20.100 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › NADP-dependent oxidoreductase domain 0.55 46.0 4.05e-01 91.1% 82.4%
4wutA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.55 45.0 4.72e-01 88.7% 99.3%
5t3uB00 3.40.50.510 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphotransferase system, mannose-type IIA component 0.55 39.0 4.40e-01 100.0% 93.2%
4f1jA00 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.55 50.0 4.73e-01 100.0% 87.0%
3gvxA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 47.0 4.66e-01 94.0% 99.4%
4c89C00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.54 49.0 3.93e-01 100.0% 67.0%
1gkrA02 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.54 48.0 3.83e-01 97.6% 95.1%
1xa3A01 3.40.50.10540 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Crotonobetainyl-coa:carnitine coa-transferase; domain 1 0.54 49.0 4.08e-01 99.4% 64.6%
2x7xA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.54 41.0 4.40e-01 80.4% 96.4%
2h3hB02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.54 43.0 4.47e-01 86.3% 95.5%
1wx0A00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.54 45.0 4.20e-01 90.5% 81.0%
5im4F00 3.40.50.510 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphotransferase system, mannose-type IIA component 0.54 38.0 4.27e-01 100.0% 94.7%
6i3mE02 3.40.50.10470 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Translation initiation factor eif-2b; domain 2 0.54 47.0 4.44e-01 95.2% 90.0%
3gdwB00 3.40.50.510 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphotransferase system, mannose-type IIA component 0.53 38.0 4.12e-01 72.6% 97.1%
1gt6A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.53 45.0 3.89e-01 92.3% 93.7%
1kcxA02 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.53 47.0 3.70e-01 98.8% 96.8%
1xo1A02 3.40.50.1010 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease 0.53 39.0 4.03e-01 96.4% 81.1%
2wqpA01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.52 47.0 4.02e-01 100.0% 91.1%
2ftyA02 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.51 46.0 3.50e-01 98.8% 65.1%
3n05A02 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.51 40.0 3.88e-01 100.0% 74.1%
ECOD (78)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4385750 2004.1.1.67 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › CbiA 0.87 83.0 7.41e-01 100.0% 78.2%
4369666 2004.1.1.43 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SRP54 0.79 74.0 6.84e-01 100.0% 85.2%
4345012 2004.1.1.43 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SRP54 0.77 72.0 6.45e-01 100.0% 76.3%
None 0.75 71.0 5.51e-01 100.0% 51.8%
3971737 2007.1.3.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like 0.75 52.0 4.28e-01 100.0% 41.0%
4076512 2007.1.3.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like 0.71 44.0 5.09e-01 100.0% 84.0%
4946250 2007.1.3.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like 0.71 49.0 5.15e-01 100.0% 78.0%
4175225 2004.1.1.231 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › RNase_J_b_CASP 0.68 55.0 5.63e-01 100.0% 86.7%
3253433 2007.1.3.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like 0.68 44.0 4.90e-01 98.2% 82.2%
3270786 2003.1.1.141 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Polysacc_synt_2, GDP_Man_Dehyd 0.67 62.0 4.92e-01 100.0% 89.0%
2062771 2007.1.2.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.67 45.0 5.12e-01 98.2% 91.3%
4594999 2007.15.1.2 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase › Nuc_deoxyrib_tr 0.66 49.0 5.26e-01 98.8% 90.7%
217023 2004.1.1.214 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › CSM2 0.64 52.0 4.97e-01 85.1% 99.0%
3618420 7512.1.1.54 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Alg14 0.64 59.0 5.43e-01 100.0% 80.9%
5041906 2002.1.1.83 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Amidohydro_1 0.64 54.0 4.11e-01 90.5% 67.5%
4948203 2003.1.5.35 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › LCM 0.63 55.0 4.59e-01 93.5% 94.1%
4954306 2007.3.1.6 a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Ligase_CoA_2 0.63 49.0 5.01e-01 99.4% 82.4%
1505917 2007.1.2.13 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_6 0.63 48.0 5.30e-01 86.3% 99.3%
1653219 2007.1.2.10 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_3 0.63 47.0 5.29e-01 81.5% 100.0%
4978603 2002.1.1.120 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.63 49.0 3.98e-01 82.1% 51.6%
3786335 2004.1.1.128 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PAXNEB 0.63 57.0 4.76e-01 100.0% 79.3%
3450037 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.62 53.0 5.10e-01 91.1% 85.8%
3404837 7585.1.1.0 a/b three-layered sandwiches › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins 0.62 50.0 5.23e-01 90.5% 92.9%
5078502 2003.1.5.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.62 53.0 4.98e-01 92.3% 83.9%
5021402 2004.1.1.1204 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF1638 0.62 57.0 4.91e-01 99.4% 95.0%
3278541 7574.1.1.12 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › PDH_E1_M 0.62 53.0 4.81e-01 92.9% 91.3%
3279820 7514.1.1.1 a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › NAD_binding_1 0.62 44.0 4.68e-01 73.2% 94.6%
3509382 2007.1.2.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.61 47.0 5.00e-01 100.0% 90.0%
3616325 7590.1.1.0 a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs 0.61 41.0 4.23e-01 97.0% 71.2%
3237563 7590.1.1.0 a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs 0.61 41.0 4.51e-01 98.2% 82.9%
5002824 2004.1.1.1204 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF1638 0.61 56.0 5.16e-01 99.4% 94.8%
5032301 2003.6.1.1 a/b three-layered sandwiches › Rossmann-like › Ribokinase-like › Ribokinase-like › PfkB 0.60 55.0 4.52e-01 100.0% 85.8%
3726503 2006.1.1.28 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › APP1_cat 0.60 53.0 4.93e-01 96.4% 91.6%
5016216 2002.1.1.83 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Amidohydro_1 0.60 51.0 3.92e-01 90.5% 72.1%
5078479 2002.1.1.83 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Amidohydro_1 0.60 51.0 4.12e-01 91.1% 64.4%
5063882 1074.1.1.6 alpha arrays › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Ribonuc_red_lgC 0.60 47.0 3.71e-01 83.3% 50.7%
3520928 7579.1.1.30 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › DUF915 0.59 54.0 4.44e-01 100.0% 73.2%
4891110 2002.1.1.0 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.59 49.0 4.11e-01 91.1% 87.9%
3286984 7574.1.1.5 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_C 0.58 50.0 4.69e-01 92.9% 82.9%
3698033 7512.1.1.6 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_20 0.58 53.0 4.55e-01 100.0% 90.2%
4934960 7574.1.1.5 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_C 0.58 50.0 4.56e-01 92.3% 81.8%
4451492 7574.1.1.5 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_C 0.58 50.0 4.71e-01 92.9% 86.7%
3604607 2002.1.1.120 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.58 51.0 4.46e-01 95.2% 80.4%
3721139 7512.1.1.6 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_20 0.58 52.0 4.56e-01 99.4% 92.9%
3800595 2006.1.6.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.57 51.0 4.64e-01 97.0% 92.9%
3878911 2006.1.6.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.57 49.0 4.90e-01 100.0% 89.1%
4984802 2002.1.1.120 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.57 50.0 4.06e-01 94.6% 84.8%
3235061 2006.1.6.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.57 50.0 4.78e-01 100.0% 82.1%
3550568 2006.1.6.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.57 50.0 4.46e-01 95.2% 90.6%
3617647 2006.1.6.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.57 51.0 4.94e-01 99.4% 88.6%
1349644 7579.1.1.11 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Cutinase 0.56 48.0 4.56e-01 99.4% 76.0%
3725364 7574.1.1.5 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_C 0.56 48.0 4.44e-01 92.3% 82.3%
3943174 7574.1.1.5 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_C 0.56 49.0 4.54e-01 92.3% 81.7%
4664847 2007.1.2.11 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_4 0.56 45.0 4.75e-01 92.3% 97.3%
3937012 2006.1.6.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.56 51.0 4.77e-01 99.4% 85.9%
4969518 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.56 47.0 4.69e-01 100.0% 87.4%
3747202 2006.1.6.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.56 49.0 3.69e-01 99.4% 38.8%
4000782 2006.1.6.9 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › Copine 0.56 51.0 4.52e-01 100.0% 84.2%
3869859 2006.1.6.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.56 50.0 4.76e-01 100.0% 84.1%
None 0.56 52.0 4.97e-01 98.8% 88.9%
4933350 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.56 37.0 4.20e-01 98.8% 88.3%
3928280 2002.1.1.220 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Menorin 0.55 51.0 4.43e-01 100.0% 96.4%
3379260 7590.1.1.2 a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Piwi 0.55 40.0 3.98e-01 97.0% 71.4%
5048984 7592.1.1.0 a/b three-layered sandwiches › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains 0.55 43.0 4.44e-01 81.5% 94.2%
3473898 2006.1.6.13 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_3 0.55 49.0 4.73e-01 100.0% 86.2%
3608577 2007.1.2.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.54 51.0 4.24e-01 100.0% 61.1%
3267747 2006.1.6.9 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › Copine 0.54 49.0 4.37e-01 100.0% 85.7%
4028454 2003.1.7.2 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › IF-2B 0.54 49.0 4.48e-01 96.4% 92.0%
4968493 7563.1.1.0 a/b three-layered sandwiches › MCP/YpsA-related › MCP/YpsA-related › MCP/YpsA-related 0.54 49.0 4.62e-01 100.0% 87.8%
3870336 2006.1.6.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.54 49.0 4.58e-01 100.0% 82.0%
3632139 2003.1.4.5 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › SIR2 0.53 48.0 4.00e-01 100.0% 91.4%
5073536 2006.1.1.18 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › HAD_2 0.53 48.0 4.38e-01 97.6% 93.3%
359061 2010.1.1.3 a/b three-layered sandwiches › EDD domain › EDD domain › EDD domain › EIIA-man 0.53 38.0 4.12e-01 72.6% 97.1%
4466712 2007.1.18.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD) › MTD 0.52 48.0 4.03e-01 100.0% 84.8%
3320006 7579.1.1.14 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Lipase_3 0.51 43.0 3.45e-01 92.3% 80.8%
4669171 2484.1.1.114 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Med13_C 0.50 41.0 3.58e-01 86.9% 84.9%
3741296 7574.1.1.0 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.50 45.0 3.98e-01 100.0% 67.3%
3585189 2003.4.1.1 a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP 0.50 32.0 3.21e-01 95.8% 62.4%
D2 medium residues 172-222
PDB
Domain cluster: representative
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2is6A04 1.10.486.10 Mainly Alpha › Orthogonal Bundle › PCRA; domain 4 › PCRA; domain 4 0.76 63.0 4.48e-01 96.1% 39.1%
1lfkA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.76 58.0 3.40e-01 82.4% 12.8%
2y4tA02 1.10.287.110 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain 0.74 47.0 4.68e-01 70.6% 63.5%
2q0oC00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.73 52.0 4.34e-01 74.5% 45.3%
3ihjA02 1.10.287.1970 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.73 48.0 5.41e-01 74.5% 92.1%
3n5lA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 51.0 4.96e-01 74.5% 66.7%
4is7A02 1.10.150.50 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 0.72 61.0 5.43e-01 94.1% 81.9%
8d8lN01 1.10.287.1480 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 50.0 4.13e-01 74.5% 43.0%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 50.0 4.03e-01 74.5% 71.6%
1xs9D00 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.69 51.0 4.47e-01 82.4% 65.4%
5aj3N01 1.10.287.1480 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.69 48.0 3.91e-01 74.5% 40.7%
4epzA00 1.25.40.810 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › UpxZ 0.66 51.0 3.66e-01 86.3% 36.4%
2vsoF01 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.65 50.0 3.22e-01 82.4% 43.3%
7ce1A01 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.64 47.0 4.71e-01 86.3% 76.9%
4ie5A02 1.20.58.1470 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FTO C-terminal domain 0.61 52.0 3.91e-01 100.0% 70.1%
2ga1A02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.60 47.0 4.24e-01 86.3% 87.3%
2gsvA00 6.10.140.40 Special › Helix non-globular › Helix Hairpins › 0.59 47.0 4.32e-01 88.2% 100.0%
2fq3A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.59 40.0 3.35e-01 70.6% 96.5%
4hteA03 1.10.167.30 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › 0.57 39.0 3.43e-01 72.5% 58.7%
1cf7B00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.57 52.0 4.36e-01 100.0% 95.1%
5cz2G00 1.10.10.200 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Integrase, N-terminal zinc-binding domain 0.57 34.0 3.64e-01 80.4% 70.7%
1r69A00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.56 39.0 3.67e-01 76.5% 58.7%
3op9A01 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.56 37.0 3.43e-01 76.5% 51.5%
2nriB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 43.0 3.56e-01 88.2% 75.0%
3h5aD01 3.90.930.70 Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › 0.52 37.0 3.26e-01 80.4% 64.8%
2e8oA01 1.10.150.50 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 0.52 38.0 3.60e-01 80.4% 77.4%
1k6yA01 1.10.10.200 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Integrase, N-terminal zinc-binding domain 0.51 32.0 3.29e-01 80.4% 67.4%
ECOD (28)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3414744 3223.1.1.1 beta sandwiches › Amiloride-sensitive cation channel 2 › Amiloride-sensitive cation channel 2 › Amiloride-sensitive cation channel 2 › ASC 0.89 60.0 3.42e-01 70.6% 86.6%
3413548 3223.1.1.1 beta sandwiches › Amiloride-sensitive cation channel 2 › Amiloride-sensitive cation channel 2 › Amiloride-sensitive cation channel 2 › ASC 0.85 59.0 3.35e-01 72.5% 87.6%
55264 604.14.1.1 alpha bundles › Spectrin repeat-like › PPK N-terminal domain-like › PPK N-terminal domain-like › PP_kinase_N 0.82 56.0 5.84e-01 72.5% 78.7%
5009551 601.7.1.3 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › PaREP1 0.81 56.0 4.14e-01 72.5% 88.8%
4996404 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.81 57.0 4.01e-01 74.5% 38.7%
3619662 192.12.1.3 alpha bundles › Long alpha-hairpin › Transcriptional repressor TraM › Transcriptional repressor TraM › DUF747 0.78 54.0 4.63e-01 72.5% 48.8%
3306315 109.4.1.189 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_2 0.77 58.0 4.69e-01 80.4% 73.7%
3352169 109.4.1.1296 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2, PPR_long, TPR_24 0.76 57.0 3.64e-01 80.4% 30.4%
3933449 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.76 53.0 4.41e-01 74.5% 87.8%
4031490 632.2.1.5 alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains › DUF1542 0.75 51.0 4.46e-01 70.6% 60.0%
3518386 192.1.1.0 alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain 0.74 51.0 4.52e-01 72.5% 50.7%
3831 604.7.1.1 alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA 0.72 50.0 4.03e-01 74.5% 71.6%
3877055 3914.1.1.1 alpha bundles › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › Anoctamin 0.72 54.0 3.20e-01 82.4% 27.5%
3935467 377.1.1.2 few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › Ribosomal_S14 0.71 50.0 3.79e-01 74.5% 33.9%
4346136 605.1.1.108 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › GrpE 0.71 48.0 4.47e-01 70.6% 60.0%
3620630 377.1.1.0 few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like 0.70 49.0 4.38e-01 74.5% 52.9%
3269316 377.1.1.2 few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › Ribosomal_S14 0.70 49.0 3.93e-01 74.5% 38.9%
4129965 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.69 47.0 3.96e-01 72.5% 42.2%
4376902 377.1.1.2 few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › Ribosomal_S14 0.69 48.0 3.84e-01 74.5% 39.4%
3890044 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.68 48.0 4.36e-01 76.5% 55.9%
4276514 3826.1.1.88 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › CC_BshC 0.68 48.0 4.34e-01 74.5% 55.7%
3797530 101.1.3.0 alpha arrays › HTH › HTH › tetra-helical, LuxR-like 0.66 51.0 4.74e-01 86.3% 81.5%
4030079 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.65 53.0 4.57e-01 90.2% 82.5%
3249557 195.1.1.3 alpha complex topology › NusB-like › NusB-like › NusB-like › NSUN5_N 0.61 51.0 3.71e-01 92.2% 38.6%
2549 101.1.1.25 alpha arrays › HTH › HTH › Three-helical HTH › DUF433 0.60 47.0 3.78e-01 86.3% 60.8%
5021368 2005.1.1.18 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › NAD_synthase 0.60 49.0 3.06e-01 94.1% 24.4%
3502612 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 42.0 3.02e-01 78.4% 51.6%
4017561 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.52 46.0 2.77e-01 100.0% 39.2%