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WAE39615.1

Arc-Vir

OP880253__WAE39615.1__FHOMOCKG-00087__00087

Identity

Accession:
OP880253 ↗
Protein ID:
WAE39615.1 ↗
Kingdom:
archaea

Quality

73.2 mean pLDDT

Taxonomy

Heunggongvirae› Uroviricota› Caudoviricetes› Nakonvirales› Ekchuahviridae› Kukulkanvirus› Methanophagales_virus_GBV302

TaxID: 2999281

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 9-55
PDB
Domain cluster: representative
CATH (37)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4e1oA03 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.86 50.0 3.84e-01 100.0% 28.6%
4u7cB04 3.30.1490.100 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › DNA polymerase, Y-family, little finger domain 0.83 48.0 3.58e-01 97.9% 25.7%
1wdkC01 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.78 41.0 2.60e-01 97.9% 11.3%
3e82E02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.70 59.0 3.87e-01 95.7% 90.0%
1l5xA00 3.40.1210.10 Alpha Beta › 3-Layer(aba) Sandwich › Stationary-phase Survival Protein Sure Homolog; Chain: A, › Survival protein SurE-like phosphatase/nucleotidase 0.70 57.0 3.56e-01 91.5% 98.9%
2bw2A01 3.10.20.420 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Bypass-of-forespore C, N-terminal domain 0.69 43.0 4.11e-01 70.2% 52.7%
4mfzA02 3.40.630.120 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › 0.66 42.0 2.97e-01 97.9% 20.4%
5xd6B01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.66 36.0 2.83e-01 95.7% 22.3%
3ihlB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 38.0 2.41e-01 97.9% 11.4%
4pk9A00 3.40.1090.10 Alpha Beta › 3-Layer(aba) Sandwich › Cytosolic phospholipase A2 catalytic domain › Cytosolic phospholipase A2 catalytic domain 0.65 56.0 3.34e-01 100.0% 76.3%
1wi0A00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.65 48.0 3.55e-01 100.0% 32.7%
4a55A01 3.10.20.770 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.65 51.0 3.12e-01 89.4% 48.4%
6sy1A02 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.64 55.0 3.25e-01 95.7% 13.8%
2y3aA01 3.10.20.770 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.64 51.0 3.14e-01 89.4% 28.9%
2wnyA00 3.30.1440.10 Alpha Beta › 2-Layer Sandwich › 50s Ribosomal Protein L5; Chain: A, › Ribosomal protein L5 0.63 50.0 3.69e-01 93.6% 50.4%
1h3dA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.62 50.0 3.71e-01 93.6% 55.7%
2ff4A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.62 42.0 3.28e-01 97.9% 33.3%
1vypX00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.60 49.0 3.00e-01 97.9% 19.1%
3rhaA00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.60 50.0 2.83e-01 100.0% 9.2%
5k1rA01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.60 50.0 3.11e-01 91.5% 26.6%
2rp4A00 6.10.280.60 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain 0.57 47.0 4.05e-01 100.0% 59.2%
1mbyA00 2.40.50.930 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.56 40.0 3.50e-01 76.6% 70.7%
3uoxB01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.55 47.0 2.89e-01 97.9% 24.4%
3cobC00 3.40.850.10 Alpha Beta › 3-Layer(aba) Sandwich › Kinesin › Kinesin motor domain 0.55 43.0 2.66e-01 93.6% 65.9%
4k7cA01 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.55 48.0 2.80e-01 100.0% 31.0%
3pvlA02 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.54 40.0 3.11e-01 97.9% 37.5%
5xc5A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 45.0 3.09e-01 93.6% 92.8%
1t17A00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.54 49.0 3.40e-01 100.0% 98.0%
3c0wA01 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.54 37.0 2.89e-01 76.6% 30.8%
1amiA04 3.20.19.10 Alpha Beta › Alpha-Beta Barrel › Aconitase; domain 4 › Aconitase, domain 4 0.54 45.0 2.94e-01 97.9% 21.3%
2kyyA00 3.30.950.30 Alpha Beta › 2-Layer Sandwich › Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 › Schlafen, AAA domain 0.53 41.0 3.09e-01 97.9% 79.7%
2p92A00 3.30.70.1490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp 0.53 48.0 3.78e-01 100.0% 78.9%
3gw6D02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 49.0 3.27e-01 100.0% 78.3%
7r5mA01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.52 45.0 2.93e-01 100.0% 30.9%
7wrgB01 3.40.850.10 Alpha Beta › 3-Layer(aba) Sandwich › Kinesin › Kinesin motor domain 0.52 43.0 2.58e-01 91.5% 48.3%
1s28A00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.52 48.0 3.40e-01 100.0% 60.0%
3w1eA03 2.40.10.410 Mainly Beta › Beta Barrel › Thrombin, subunit H › FlgT, C-terminal domain 0.50 35.0 3.00e-01 78.7% 41.6%
ECOD (52)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3617823 3016.1.1.0 ↗ a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.89 52.0 3.99e-01 100.0% 30.1%
3800293 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.88 47.0 3.66e-01 97.9% 28.0%
3594033 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.87 49.0 3.02e-01 100.0% 12.0%
5033602 3016.1.1.0 ↗ a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.83 49.0 3.69e-01 100.0% 26.7%
3300895 375.13.1.3 ↗ few secondary structure elements › Rubredoxin-like › Mycobacterium tuberculosis Topoisomerase I C-terminal domain › Mycobacterium tuberculosis Topoisomerase I C-terminal domain › ubiquitin 0.81 42.0 3.94e-01 97.9% 43.6%
4407937 3957.1.1.2 ↗ a+b two layers › EKC/KEOPS complex subunit GON7 › EKC/KEOPS complex subunit GON7 › EKC/KEOPS complex subunit GON7 › DUF4611 0.81 46.0 4.17e-01 100.0% 45.0%
4888514 323.1.1.5 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Condensation 0.79 42.0 2.60e-01 93.6% 10.3%
3377269 192.18.1.0 ↗ alpha bundles › Long alpha-hairpin › MxiH-like › MxiH-like 0.78 46.0 2.66e-01 100.0% 7.3%
3917386 233.1.1.1 ↗ a+b two layers › MHC antigen-recognition domain › MHC antigen-recognition domain › MHC antigen-recognition domain › MHC_I 0.78 50.0 3.33e-01 100.0% 17.7%
4955569 873.1.1.1 ↗ a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain › V4R 0.76 44.0 2.90e-01 100.0% 15.4%
3741882 2004.1.1.250 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd 0.74 50.0 2.97e-01 70.2% 57.4%
3282392 3016.1.1.0 ↗ a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.73 39.0 3.09e-01 97.9% 27.0%
4169399 304.14.1.1 ↗ a+b two layers › Alpha-beta plaits › Sporulation related repeat (SPOR) › Sporulation related repeat (SPOR) › SPOR 0.73 37.0 3.06e-01 95.7% 27.8%
3781870 263.1.1.1 ↗ a+b three layers › SRF-like › SRF-like › SRF-like › SRF-TF 0.72 47.0 3.82e-01 95.7% 37.6%
3846164 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.69 56.0 3.43e-01 91.5% 90.8%
3242234 206.1.1.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.69 46.0 2.61e-01 97.9% 6.3%
3806670 108.1.1.20 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_like 0.67 40.0 2.98e-01 91.5% 24.3%
3807532 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 53.0 3.02e-01 91.5% 61.0%
3303720 3336.1.1.1 ↗ alpha complex topology › plant-specific ROP nucleotide exchanger (PRONE) domain › plant-specific ROP nucleotide exchanger (PRONE) domain › plant-specific ROP nucleotide exchanger (PRONE) domain › PRONE 0.63 54.0 3.19e-01 95.7% 16.4%
3853833 304.9.1.81 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RBD_AKAP-17A 0.63 56.0 3.84e-01 100.0% 59.4%
3617003 4004.1.1.0 ↗ beta sandwiches › NAD kinase beta sandwich domain-like › NAD kinase beta sandwich domain-like › NAD kinase beta sandwich domain-like 0.62 35.0 2.48e-01 95.7% 17.0%
3753477 304.9.1.81 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RBD_AKAP-17A 0.62 56.0 3.50e-01 100.0% 38.4%
3959053 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.62 52.0 3.49e-01 93.6% 77.8%
3587631 186.1.1.0 ↗ alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N 0.61 50.0 3.56e-01 100.0% 30.0%
3698801 2004.1.1.250 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd 0.61 52.0 3.07e-01 97.9% 49.4%
4280539 109.21.1.8 ↗ alpha superhelices › Repetitive alpha hairpins › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › WD40 0.61 47.0 2.59e-01 87.2% 37.3%
3581193 2004.1.1.250 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd 0.60 52.0 3.08e-01 100.0% 61.8%
4034385 7523.1.1.0 ↗ a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II 0.60 53.0 3.99e-01 97.9% 50.9%
5025916 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.59 54.0 3.72e-01 100.0% 35.2%
3705380 857.1.1.19 ↗ a+b duplicates or obligate multimers › Cell division protein ZapA-like › Cell division protein ZapA-like › Cell division protein ZapA-like › Ax_dynein_light 0.58 52.0 3.87e-01 100.0% 87.8%
None — 0.58 52.0 2.85e-01 100.0% 23.8%
5004463 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.57 48.0 2.94e-01 97.9% 71.9%
2755218 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.57 51.0 3.27e-01 100.0% 48.5%
3672275 2004.1.1.250 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd 0.56 47.0 2.81e-01 95.7% 55.7%
3311607 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.56 42.0 3.23e-01 83.0% 49.1%
3782687 2003.1.5.63 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › CARME 0.56 47.0 2.79e-01 100.0% 52.3%
3981752 829.1.1.1 ↗ a+b duplicates or obligate multimers › NinB › NinB › NinB › NinB 0.56 46.0 3.45e-01 97.9% 47.7%
3444901 4954.1.1.0 ↗ a+b complex topology › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit 0.55 50.0 3.36e-01 100.0% 32.6%
4019036 304.3.1.15 ↗ a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › PF31052 0.55 48.0 4.12e-01 93.6% 94.3%
3316686 2484.1.1.157 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF4371 0.55 41.0 2.69e-01 87.2% 28.3%
4033072 101.1.9.32 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › ANT 0.54 43.0 3.50e-01 87.2% 97.6%
1566324 244.1.1.0 ↗ a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C 0.53 47.0 3.11e-01 97.9% 77.1%
3376457 2484.1.1.110 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MULE 0.53 37.0 2.96e-01 76.6% 56.0%
3603146 2008.1.1.95 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DpnII 0.53 46.0 2.78e-01 95.7% 83.2%
3890428 109.3.1.96 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank+Ank_2+Ank_4 0.52 44.0 2.98e-01 93.6% 77.8%
3305417 4232.1.1.0 ↗ few secondary structure elements › Ribosomal protein bL28-related › Ribosomal protein bL28-related › Ribosomal protein L28 0.52 36.0 3.54e-01 76.6% 94.5%
1117773 1.1.13.24 ↗ beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › DTP-pb9_A-dom_C,DTP-pb9_A-dom_N 0.52 45.0 3.94e-01 93.6% 70.1%
3789630 633.23.1.0 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin 0.52 49.0 3.01e-01 100.0% 74.8%
4924546 325.1.1.9 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › CO dehydrogenase molybdoprotein N-domain-like › CPSase_L_D2 0.52 35.0 2.81e-01 72.3% 41.1%
5019906 3457.1.1.3 ↗ alpha bundles › GxGD membrane protease › GxGD membrane protease › GxGD membrane protease › Arc_PepC_II 0.52 45.0 2.86e-01 100.0% 53.9%
3400912 868.1.1.3 ↗ a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › Med20 0.51 39.0 2.67e-01 93.6% 74.1%
4965204 7523.1.1.0 ↗ a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II 0.50 47.0 3.37e-01 100.0% 78.3%