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WDS52887.1
Arc-VirOP999032__WDS52887.1__X__00005
Identity
- Accession:
- OP999032 ↗
- Protein ID:
- WDS52887.1 ↗
- Kingdom:
- archaea
Quality
64.4
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 143-273
D2
high
residues 278-381
Domain cluster:
representative
CATH (65)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4alyB00 | 1.10.3160.10 | Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 | 0.77 | 71.0 | 5.77e-01 | 100.0% | 88.2% |
| 3nftA00 | 1.20.1710.10 | Mainly Alpha › Up-down Bundle › IpaD-like › IpaD-like | 0.76 | 62.0 | 4.57e-01 | 87.5% | 80.2% |
| 8d3mA02 | 1.20.120.920 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain | 0.73 | 54.0 | 4.11e-01 | 84.6% | 33.8% |
| 2m6uA00 | 1.20.81.20 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › | 0.72 | 54.0 | 5.93e-01 | 96.2% | 100.0% |
| 3owaB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.71 | 57.0 | 4.92e-01 | 84.6% | 64.3% |
| 2z1qB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.71 | 55.0 | 5.06e-01 | 82.7% | 66.2% |
| 4e40A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.70 | 56.0 | 4.28e-01 | 87.5% | 83.3% |
| 8hk0B03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.69 | 55.0 | 4.95e-01 | 82.7% | 65.9% |
| 6i9kA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.69 | 56.0 | 3.98e-01 | 87.5% | 38.1% |
| 6p73A02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.68 | 55.0 | 4.96e-01 | 86.5% | 65.7% |
| 2bl2A00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.68 | 60.0 | 5.32e-01 | 100.0% | 85.9% |
| 3cazB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.68 | 55.0 | 4.39e-01 | 87.5% | 88.1% |
| 1qdbA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.68 | 55.0 | 4.96e-01 | 87.5% | 67.8% |
| 7e4gA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.67 | 52.0 | 4.25e-01 | 83.7% | 100.0% |
| 1jqkA03 | 1.20.1270.30 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.67 | 53.0 | 4.53e-01 | 86.5% | 92.6% |
| 2q12A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.67 | 51.0 | 3.94e-01 | 81.7% | 74.0% |
| 3gi7A00 | 1.20.1270.180 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.67 | 53.0 | 5.41e-01 | 85.6% | 95.1% |
| 1h6gA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.67 | 54.0 | 5.16e-01 | 86.5% | 80.7% |
| 2qffA00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.67 | 44.0 | 4.98e-01 | 80.8% | 94.6% |
| 2etdA00 | 1.20.1440.20 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain | 0.66 | 48.0 | 4.33e-01 | 84.6% | 55.3% |
| 7s0rB01 | 1.20.81.20 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › | 0.66 | 47.0 | 5.24e-01 | 87.5% | 100.0% |
| 1vljA02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.66 | 47.0 | 3.74e-01 | 81.7% | 36.5% |
| 4al0A00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.65 | 59.0 | 5.27e-01 | 100.0% | 85.6% |
| 3ljbA00 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.65 | 56.0 | 4.37e-01 | 93.3% | 54.8% |
| 6d5xA00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.65 | 52.0 | 4.64e-01 | 87.5% | 95.4% |
| 6me6B02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.65 | 52.0 | 3.85e-01 | 87.5% | 40.7% |
| 2qupA00 | 1.20.120.490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain | 0.64 | 48.0 | 4.59e-01 | 87.5% | 68.9% |
| 1k32A03 | 3.30.750.44 | Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › | 0.64 | 40.0 | 4.56e-01 | 87.5% | 88.9% |
| 2y44A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.64 | 53.0 | 4.41e-01 | 90.4% | 95.7% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.64 | 50.0 | 4.62e-01 | 86.5% | 64.2% |
| 3uonA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.64 | 52.0 | 3.78e-01 | 87.5% | 41.9% |
| 4djhA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.63 | 51.0 | 3.74e-01 | 87.5% | 42.5% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.63 | 49.0 | 4.75e-01 | 84.6% | 79.3% |
| 3kdrA01 | 1.20.1270.210 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.63 | 44.0 | 4.39e-01 | 72.1% | 90.6% |
| 1bgfA00 | 1.10.532.10 | Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain | 0.62 | 37.0 | 3.55e-01 | 70.2% | 49.2% |
| 1x8zB00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.62 | 50.0 | 4.45e-01 | 85.6% | 63.3% |
| 3pltA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.62 | 55.0 | 4.40e-01 | 100.0% | 90.7% |
| 3d2eA06 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.61 | 44.0 | 4.33e-01 | 81.7% | 69.9% |
| 1qv9A02 | 6.10.140.120 | Special › Helix non-globular › Helix Hairpins › | 0.61 | 48.0 | 4.89e-01 | 85.6% | 95.1% |
| 3ddlA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 49.0 | 3.71e-01 | 87.5% | 97.2% |
| 2oezA02 | 1.10.3900.10 | Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like | 0.61 | 45.0 | 3.93e-01 | 78.8% | 74.8% |
| 1tj7A01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.59 | 42.0 | 4.27e-01 | 89.4% | 73.3% |
| 1jq5A02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.59 | 44.0 | 3.58e-01 | 79.8% | 43.2% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.59 | 49.0 | 4.89e-01 | 87.5% | 94.3% |
| 2e8gA01 | 1.20.1440.150 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.59 | 47.0 | 4.44e-01 | 85.6% | 73.4% |
| 3a06B03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.59 | 39.0 | 4.15e-01 | 88.5% | 79.5% |
| 3a7kB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.57 | 49.0 | 3.68e-01 | 94.2% | 76.4% |
| 4cgkA01 | 6.10.250.3150 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.57 | 47.0 | 3.68e-01 | 88.5% | 95.3% |
| 1cnt200 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.57 | 45.0 | 4.24e-01 | 86.5% | 74.6% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 50.0 | 4.04e-01 | 95.2% | 94.8% |
| 2hqcA01 | 1.20.1640.10 | Mainly Alpha › Up-down Bundle › Multidrug efflux transporter AcrB transmembrane fold › Multidrug efflux transporter AcrB transmembrane domain | 0.56 | 50.0 | 4.08e-01 | 100.0% | 81.2% |
| 2bnlC00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.56 | 39.0 | 3.56e-01 | 71.2% | 76.1% |
| 2olcA02 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.56 | 48.0 | 3.67e-01 | 100.0% | 76.2% |
| 6k9pB02 | 1.20.1300.20 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Peptidase C65 Otubain, subdomain 2 | 0.55 | 47.0 | 4.14e-01 | 93.3% | 76.3% |
| 5b00A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.55 | 43.0 | 3.26e-01 | 85.6% | 40.6% |
| 2e9fB01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.54 | 40.0 | 4.22e-01 | 77.9% | 84.4% |
| 6cnzF00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.54 | 46.0 | 4.06e-01 | 96.2% | 82.3% |
| 6c1qB02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.54 | 45.0 | 3.32e-01 | 91.3% | 100.0% |
| 5c4yA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 42.0 | 3.87e-01 | 86.5% | 86.0% |
| 3u52D00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.52 | 46.0 | 3.30e-01 | 100.0% | 74.4% |
| 2dg7A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 43.0 | 3.56e-01 | 91.3% | 62.9% |
| 5j6bD01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.51 | 44.0 | 3.27e-01 | 97.1% | 66.6% |
| 3eabE00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.51 | 38.0 | 4.16e-01 | 79.8% | 98.8% |
| 1w9rA00 | 1.20.58.440 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A | 0.51 | 42.0 | 4.06e-01 | 97.1% | 79.0% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.51 | 41.0 | 4.21e-01 | 87.5% | 97.1% |
ECOD (57)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3412881 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.83 | 51.0 | 5.70e-01 | 74.0% | 80.0% |
| 4479999 | 632.19.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A | 0.77 | 60.0 | 5.99e-01 | 90.4% | 81.0% |
| 3976111 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.77 | 60.0 | 6.10e-01 | 90.4% | 85.0% |
| 4283835 | 1128.1.1.8 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › PF29574 | 0.76 | 56.0 | 5.63e-01 | 93.3% | 76.2% |
| 3723550 | 5038.2.1.1 ↗ | alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like › MAPEG | 0.76 | 62.0 | 5.50e-01 | 87.5% | 62.1% |
| 3988174 | 632.19.1.3 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A › DUF1542 | 0.76 | 55.0 | 5.98e-01 | 82.7% | 91.8% |
| 4017513 | 5038.2.1.1 ↗ | alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like › MAPEG | 0.74 | 61.0 | 5.54e-01 | 90.4% | 65.7% |
| 4017411 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.73 | 63.0 | 5.63e-01 | 96.2% | 84.7% |
| 3383049 | 4009.1.1.18 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › FPP | 0.72 | 50.0 | 5.73e-01 | 78.8% | 100.0% |
| 3354093 | 632.1.1.16 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › FPP | 0.72 | 50.0 | 5.73e-01 | 79.8% | 100.0% |
| 3389526 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.72 | 58.0 | 5.96e-01 | 90.4% | 90.0% |
| 4980622 | 633.6.1.3 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › HpaB | 0.72 | 57.0 | 4.58e-01 | 85.6% | 50.7% |
| 3858695 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.72 | 55.0 | 6.05e-01 | 91.3% | 98.8% |
| 5045176 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.71 | 60.0 | 6.04e-01 | 90.4% | 95.1% |
| 5048247 | 632.1.1.3 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Alpha-mann_mid | 0.71 | 57.0 | 5.84e-01 | 86.5% | 90.0% |
| 5023098 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.70 | 57.0 | 5.40e-01 | 87.5% | 89.6% |
| 3215515 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.70 | 56.0 | 6.00e-01 | 84.6% | 97.8% |
| 3232705 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.70 | 58.0 | 5.66e-01 | 90.4% | 83.5% |
| 4031187 | 632.19.1.3 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A › DUF1542 | 0.70 | 49.0 | 5.52e-01 | 95.2% | 100.0% |
| 3330285 | 7064.1.1.1 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 | 0.70 | 48.0 | 4.38e-01 | 72.1% | 54.1% |
| 4025051 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.70 | 56.0 | 4.92e-01 | 85.6% | 80.7% |
| 4057034 | 181.1.1.0 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins | 0.69 | 44.0 | 5.06e-01 | 88.5% | 89.3% |
| 4928071 | 3239.1.1.1 ↗ | alpha complex topology › Cas1 › Cas1 › Cas1 › Cas_Cas1 | 0.68 | 54.0 | 3.86e-01 | 86.5% | 28.4% |
| 3466160 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.68 | 57.0 | 5.32e-01 | 92.3% | 93.1% |
| 5028679 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.67 | 54.0 | 5.46e-01 | 86.5% | 91.3% |
| 3911781 | 5038.2.1.1 ↗ | alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like › MAPEG | 0.67 | 60.0 | 5.36e-01 | 100.0% | 86.7% |
| 3471803 | 5038.2.1.1 ↗ | alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like › MAPEG | 0.67 | 59.0 | 5.57e-01 | 96.2% | 86.4% |
| 4034211 | 632.19.1.3 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A › DUF1542 | 0.67 | 58.0 | 5.47e-01 | 94.2% | 95.2% |
| 3587197 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.66 | 54.0 | 4.86e-01 | 90.4% | 71.3% |
| 3563670 | 3758.1.1.54 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › ApoL | 0.66 | 46.0 | 4.95e-01 | 99.0% | 84.4% |
| 3413892 | 632.19.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A | 0.66 | 54.0 | 5.17e-01 | 96.2% | 77.5% |
| 4172479 | 633.6.1.0 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like | 0.66 | 53.0 | 4.85e-01 | 86.5% | 68.9% |
| 3173484 | 633.21.1.17 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › PFF1_TM | 0.66 | 52.0 | 5.11e-01 | 84.6% | 97.3% |
| 4011280 | 611.9.1.0 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain | 0.65 | 55.0 | 5.01e-01 | 93.3% | 89.3% |
| 4014870 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.65 | 58.0 | 5.28e-01 | 100.0% | 88.6% |
| 3646192 | 611.7.1.11 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › DUF7032 | 0.65 | 58.0 | 5.39e-01 | 100.0% | 85.4% |
| 3385721 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.64 | 55.0 | 4.59e-01 | 97.1% | 53.5% |
| 5004943 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.64 | 57.0 | 4.90e-01 | 98.1% | 91.3% |
| 5065387 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.63 | 50.0 | 4.91e-01 | 84.6% | 78.9% |
| 3736708 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.63 | 52.0 | 4.67e-01 | 92.3% | 81.3% |
| 3418913 | 611.7.1.1 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › MLKL_N | 0.62 | 55.0 | 5.05e-01 | 96.2% | 76.3% |
| 3226726 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.62 | 46.0 | 4.49e-01 | 82.7% | 70.4% |
| 3185570 | 3755.4.1.3 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Helo_like_N | 0.62 | 54.0 | 4.64e-01 | 99.0% | 73.7% |
| 3318741 | 5059.1.1.55 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › TauE | 0.62 | 50.0 | 3.56e-01 | 88.5% | 80.0% |
| 954338 | 139.2.1.1 ↗ | few secondary structure elements › Multiheme cytochromes › Di-heme elbow motif › Di-heme elbow motif › Cytochrom_C552 | 0.61 | 48.0 | 3.11e-01 | 86.5% | 17.8% |
| 3830361 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.61 | 48.0 | 4.23e-01 | 85.6% | 57.4% |
| 3728842 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.60 | 51.0 | 4.58e-01 | 96.2% | 84.7% |
| 3579748 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.60 | 46.0 | 3.95e-01 | 82.7% | 94.7% |
| 3540972 | 174.1.1.34 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › FAM70 | 0.60 | 48.0 | 4.26e-01 | 86.5% | 63.3% |
| 3225470 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.58 | 47.0 | 4.17e-01 | 88.5% | 60.6% |
| 3681139 | 5001.1.1.172 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › PIGO_PIGG | 0.58 | 48.0 | 3.59e-01 | 91.3% | 75.3% |
| 4984050 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.57 | 50.0 | 4.37e-01 | 97.1% | 80.6% |
| 1518845 | 601.41.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › C-terminal domain in uncharacterized DUF3829-like protein › C-terminal domain in uncharacterized DUF3829-like protein › DUF3829_2nd | 0.57 | 51.0 | 5.07e-01 | 98.1% | 94.4% |
| 3934670 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.57 | 45.0 | 3.82e-01 | 85.6% | 92.6% |
| 4023478 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.56 | 44.0 | 3.69e-01 | 86.5% | 52.1% |
| 2723199 | 3455.1.1.0 ↗ | alpha arrays › WY-domain in RXLR effectors › WY-domain in RXLR effectors › WY-domain in RXLR effectors | 0.56 | 47.0 | 4.48e-01 | 92.3% | 90.1% |
| 3334314 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.54 | 43.0 | 3.72e-01 | 87.5% | 70.6% |
D3
high
residues 497-639
Domain cluster:
representative
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1w98B02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.71 | 36.0 | 4.07e-01 | 71.3% | 62.3% |
| 4bejB02 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.61 | 43.0 | 3.78e-01 | 73.4% | 82.5% |
| 3pvuA01 | 1.10.287.1270 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.57 | 37.0 | 4.16e-01 | 70.6% | 83.8% |
| 1e94E03 | 1.10.8.60 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.55 | 32.0 | 3.60e-01 | 72.7% | 74.5% |
| 4an8A02 | 1.10.132.100 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.53 | 38.0 | 4.13e-01 | 76.9% | 87.7% |
| 4mycA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.53 | 38.0 | 2.88e-01 | 72.7% | 91.2% |
| 4im9B00 | 1.10.860.10 | Mainly Alpha › Orthogonal Bundle › DNAb Helicase; Chain A › DNAb Helicase; Chain A | 0.52 | 36.0 | 3.76e-01 | 70.6% | 92.6% |
| 3p9dE01 | 1.10.560.10 | Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain | 0.51 | 37.0 | 3.09e-01 | 76.2% | 87.9% |
ECOD (2)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4994979 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.52 | 27.0 | 2.45e-01 | 74.1% | 34.7% |
| 4353063 | 621.1.1.3 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB | 0.51 | 40.0 | 3.89e-01 | 83.2% | 86.3% |
D4
medium
residues 640-716_883-895
Domain cluster:
representative
CATH (30)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2g8lB01 | 1.10.8.380 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 | 0.73 | 48.0 | 5.43e-01 | 97.8% | 89.6% |
| 3o7pA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.67 | 55.0 | 4.19e-01 | 91.1% | 87.2% |
| 1c9bA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.66 | 52.0 | 5.08e-01 | 100.0% | 78.4% |
| 3pwfA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.65 | 45.0 | 3.97e-01 | 72.2% | 54.2% |
| 1zp2A02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.64 | 50.0 | 4.68e-01 | 100.0% | 67.9% |
| 3lynB00 | 1.20.150.10 | Mainly Alpha › Up-down Bundle › Lysin › Fertilization protein | 0.63 | 49.0 | 4.43e-01 | 83.3% | 85.5% |
| 2mtqA00 | 1.20.58.130 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 43.0 | 4.81e-01 | 82.2% | 90.4% |
| 2z15A00 | 3.90.640.90 | Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › Anti-proliferative protein, N-terminal domain | 0.61 | 55.0 | 5.02e-01 | 100.0% | 88.2% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.60 | 54.0 | 4.52e-01 | 97.8% | 81.9% |
| 3bvoA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.60 | 42.0 | 4.37e-01 | 73.3% | 86.0% |
| 4a25B01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.59 | 53.0 | 4.34e-01 | 98.9% | 73.9% |
| 3a06B03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.59 | 43.0 | 4.35e-01 | 76.7% | 78.4% |
| 6f1eA01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.58 | 46.0 | 3.91e-01 | 83.3% | 61.9% |
| 1chuA03 | 1.20.58.100 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain | 0.58 | 42.0 | 4.25e-01 | 82.2% | 77.3% |
| 6nplA01 | 1.20.1740.10 | Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I | 0.57 | 49.0 | 3.16e-01 | 97.8% | 78.4% |
| 1vmgA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.56 | 37.0 | 3.90e-01 | 74.4% | 74.4% |
| 1yvwA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.56 | 38.0 | 3.82e-01 | 92.2% | 68.5% |
| 1j1jA02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.55 | 40.0 | 4.10e-01 | 82.2% | 78.8% |
| 8hk0B03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.55 | 49.0 | 4.28e-01 | 98.9% | 93.5% |
| 7vwtA01 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.55 | 50.0 | 3.38e-01 | 98.9% | 41.9% |
| 8b70A01 | 1.20.1740.10 | Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I | 0.55 | 48.0 | 3.16e-01 | 98.9% | 74.4% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.54 | 40.0 | 3.69e-01 | 77.8% | 81.2% |
| 2e9xA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 42.0 | 3.72e-01 | 94.4% | 57.8% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.53 | 41.0 | 3.59e-01 | 85.6% | 79.6% |
| 4x5mA00 | 1.20.1280.290 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.53 | 36.0 | 3.74e-01 | 93.3% | 74.4% |
| 2vm6A00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.52 | 40.0 | 3.42e-01 | 82.2% | 50.7% |
| 3fflA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.52 | 33.0 | 2.96e-01 | 78.9% | 43.7% |
| 4rngC00 | 1.20.1280.290 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.52 | 39.0 | 4.04e-01 | 82.2% | 84.3% |
| 2k19A00 | 1.20.1440.140 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.51 | 45.0 | 4.42e-01 | 100.0% | 91.8% |
| 1y6xA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.51 | 37.0 | 3.75e-01 | 96.7% | 77.0% |
ECOD (51)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4550256 | 604.12.1.76 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › IspA | 0.73 | 49.0 | 5.31e-01 | 80.0% | 82.7% |
| 3986007 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.70 | 58.0 | 4.58e-01 | 92.2% | 88.1% |
| 3796068 | 148.1.3.40 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › ORC5_lid | 0.70 | 46.0 | 4.57e-01 | 85.6% | 64.2% |
| 3391293 | 101.1.10.13 ↗ | alpha arrays › HTH › HTH › Cyclin-like › DUF3452 | 0.69 | 63.0 | 5.71e-01 | 100.0% | 82.5% |
| 5037363 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.67 | 55.0 | 4.39e-01 | 91.1% | 89.7% |
| 3600731 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.66 | 57.0 | 5.26e-01 | 94.4% | 87.0% |
| 4964574 | 5065.1.1.1 ↗ | alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › ABC-3 | 0.66 | 52.0 | 3.65e-01 | 84.4% | 62.5% |
| 3799135 | 633.15.1.0 ↗ | alpha bundles › Bromodomain-like › alpha-ketoacid dehydrogenase kinase-N › alpha-ketoacid dehydrogenase kinase-N | 0.65 | 56.0 | 4.66e-01 | 92.2% | 69.3% |
| 3390921 | 142.1.1.0 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors | 0.64 | 47.0 | 4.97e-01 | 84.4% | 88.7% |
| 4015513 | 610.4.1.1 ↗ | alpha arrays › ERP29 C domain-like › YqeY domain › YqeY domain › YqeY | 0.63 | 56.0 | 4.68e-01 | 95.6% | 62.0% |
| 5082862 | 150.1.1.3 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin | 0.63 | 56.0 | 4.60e-01 | 98.9% | 77.0% |
| 3801576 | 4953.1.1.0 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like | 0.62 | 53.0 | 5.12e-01 | 100.0% | 85.0% |
| 3620069 | 633.1.1.0 ↗ | alpha bundles › Bromodomain-like › Bromodomain › Bromodomain | 0.61 | 52.0 | 4.97e-01 | 100.0% | 81.0% |
| 3830022 | 101.1.10.3 ↗ | alpha arrays › HTH › HTH › Cyclin-like › TFIIB | 0.61 | 45.0 | 4.24e-01 | 97.8% | 64.5% |
| 3973839 | 610.4.1.1 ↗ | alpha arrays › ERP29 C domain-like › YqeY domain › YqeY domain › YqeY | 0.61 | 51.0 | 4.42e-01 | 94.4% | 88.9% |
| 3472879 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.61 | 44.0 | 4.38e-01 | 81.1% | 71.6% |
| 3386043 | 610.4.1.1 ↗ | alpha arrays › ERP29 C domain-like › YqeY domain › YqeY domain › YqeY | 0.61 | 52.0 | 4.46e-01 | 95.6% | 90.3% |
| 3302202 | 3745.1.1.1 ↗ | alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Na_Ca_ex | 0.60 | 49.0 | 3.29e-01 | 87.8% | 56.8% |
| 4211332 | 633.10.1.35 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › NKAIN | 0.60 | 51.0 | 4.64e-01 | 92.2% | 86.7% |
| 3755802 | 604.12.1.98 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › NKAIN | 0.60 | 47.0 | 4.47e-01 | 83.3% | 84.8% |
| 3742733 | 610.4.1.1 ↗ | alpha arrays › ERP29 C domain-like › YqeY domain › YqeY domain › YqeY | 0.59 | 51.0 | 5.04e-01 | 98.9% | 98.0% |
| 3706007 | 633.6.1.0 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like | 0.59 | 52.0 | 4.15e-01 | 100.0% | 83.8% |
| 3645236 | 633.10.1.18 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › THU_Piezo1 | 0.58 | 48.0 | 4.65e-01 | 92.2% | 80.0% |
| 5039404 | 604.2.1.0 ↗ | alpha bundles › Spectrin repeat-like › Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain › Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain | 0.58 | 41.0 | 4.39e-01 | 80.0% | 88.0% |
| 3783816 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.58 | 47.0 | 4.38e-01 | 87.8% | 100.0% |
| 4016845 | 622.1.1.1 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › HSCB_C | 0.57 | 41.0 | 4.13e-01 | 74.4% | 88.9% |
| 5013157 | 4163.1.1.0 ↗ | alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like | 0.57 | 39.0 | 3.51e-01 | 72.2% | 91.5% |
| 3739550 | 150.1.1.107 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › PF26021 | 0.57 | 46.0 | 3.34e-01 | 87.8% | 79.6% |
| 3934523 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.56 | 44.0 | 4.36e-01 | 82.2% | 84.2% |
| 4127 | 159.1.2.2 ↗ | alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related › MazG | 0.56 | 37.0 | 3.88e-01 | 90.0% | 72.3% |
| 3457403 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.56 | 48.0 | 4.25e-01 | 93.3% | 93.1% |
| 3453655 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.56 | 47.0 | 4.23e-01 | 91.1% | 88.8% |
| 4182983 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.56 | 42.0 | 3.93e-01 | 91.1% | 64.5% |
| 5055868 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.55 | 37.0 | 4.04e-01 | 91.1% | 82.7% |
| 3572529 | 601.1.2.96 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › MENTAL | 0.54 | 47.0 | 4.27e-01 | 98.9% | 95.2% |
| 3563979 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.54 | 46.0 | 3.88e-01 | 91.1% | 79.3% |
| 3876785 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.54 | 45.0 | 4.41e-01 | 92.2% | 90.0% |
| 5024994 | 4163.1.1.0 ↗ | alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like | 0.54 | 38.0 | 3.50e-01 | 74.4% | 85.0% |
| 4099493 | 622.1.1.1 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › HSCB_C | 0.54 | 42.0 | 4.19e-01 | 83.3% | 80.0% |
| 4026202 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.54 | 43.0 | 4.39e-01 | 97.8% | 87.8% |
| 3456443 | 2003.1.5.30 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_7 | 0.53 | 41.0 | 2.80e-01 | 83.3% | 23.9% |
| 3626530 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.53 | 41.0 | 4.07e-01 | 82.2% | 83.2% |
| 3479583 | 2003.1.9.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Activating enzymes of the ubiquitin-like proteins › ThiF | 0.53 | 46.0 | 2.82e-01 | 96.7% | 17.5% |
| 3695505 | 604.3.1.11 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › DUF155 | 0.53 | 41.0 | 3.78e-01 | 82.2% | 84.3% |
| 3496761 | 2003.1.9.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Activating enzymes of the ubiquitin-like proteins | 0.53 | 47.0 | 3.03e-01 | 100.0% | 22.8% |
| 4956253 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.52 | 45.0 | 4.31e-01 | 95.6% | 98.1% |
| 1411677 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.52 | 39.0 | 4.04e-01 | 82.2% | 84.3% |
| 5043430 | 6155.1.1.0 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter | 0.52 | 36.0 | 3.90e-01 | 73.3% | 86.7% |
| 5029393 | 6155.1.1.0 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter | 0.51 | 36.0 | 3.64e-01 | 91.1% | 71.9% |
| 4235024 | 109.4.1.2782 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_6, PF30363, PF30475 | 0.51 | 43.0 | 2.58e-01 | 91.1% | 19.1% |
| 4994749 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.51 | 44.0 | 4.13e-01 | 96.7% | 95.5% |
D5
medium
residues 717-882
Domain cluster:
representative
CATH (26)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1nzeA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.75 | 50.0 | 6.03e-01 | 70.5% | 100.0% |
| 3wscA00 | 1.20.1420.20 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › M75 peptidase, HXXE motif | 0.71 | 53.0 | 4.59e-01 | 76.5% | 79.7% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.68 | 50.0 | 5.49e-01 | 93.4% | 94.0% |
| 4xpwA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.68 | 50.0 | 5.51e-01 | 94.0% | 95.4% |
| 7drjB01 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.63 | 47.0 | 4.59e-01 | 77.7% | 82.0% |
| 1x8zB00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.62 | 38.0 | 4.05e-01 | 80.1% | 68.7% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.61 | 50.0 | 4.57e-01 | 86.1% | 66.8% |
| 4i1mB01 | 1.20.120.1700 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.61 | 45.0 | 5.00e-01 | 78.9% | 97.7% |
| 1k90B03 | 1.20.140.60 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.60 | 36.0 | 4.19e-01 | 80.7% | 84.3% |
| 1rj1A00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.59 | 39.0 | 4.18e-01 | 92.2% | 76.4% |
| 1xzpA02 | 1.20.120.430 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 | 0.57 | 48.0 | 4.88e-01 | 88.0% | 95.2% |
| 1zb1A00 | 1.25.40.280 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › alix/aip1 like domains | 0.57 | 48.0 | 3.69e-01 | 88.6% | 80.1% |
| 2di3B02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.57 | 41.0 | 4.21e-01 | 73.5% | 100.0% |
| 8sbeA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.56 | 39.0 | 3.82e-01 | 71.1% | 72.2% |
| 6t0bc02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.56 | 51.0 | 4.83e-01 | 95.2% | 89.0% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.55 | 36.0 | 4.22e-01 | 76.5% | 90.2% |
| 1m56C02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.55 | 50.0 | 4.75e-01 | 97.0% | 90.8% |
| 4aciA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 38.0 | 3.78e-01 | 71.7% | 96.6% |
| 1jr3C02 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.54 | 37.0 | 4.29e-01 | 71.1% | 98.4% |
| 2yevA03 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.53 | 47.0 | 4.55e-01 | 95.2% | 89.7% |
| 2m63A00 | 1.25.40.780 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.53 | 36.0 | 3.74e-01 | 78.3% | 73.2% |
| 2lqgA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.51 | 37.0 | 4.02e-01 | 78.9% | 88.4% |
| 3l6aA01 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.51 | 37.0 | 3.56e-01 | 74.1% | 71.1% |
| 7akwA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 45.0 | 4.06e-01 | 94.6% | 76.1% |
| 2vxxA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.51 | 36.0 | 3.60e-01 | 72.3% | 94.8% |
| 7q37A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.50 | 44.0 | 4.10e-01 | 96.4% | 80.4% |
ECOD (31)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3589765 | 601.41.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › C-terminal domain in uncharacterized DUF3829-like protein › C-terminal domain in uncharacterized DUF3829-like protein | 0.70 | 39.0 | 5.11e-01 | 83.7% | 98.9% |
| 3815499 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.64 | 41.0 | 4.46e-01 | 80.1% | 76.4% |
| 3621550 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 40.0 | 4.63e-01 | 83.7% | 94.2% |
| 3726193 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 42.0 | 4.04e-01 | 73.5% | 77.4% |
| 3931457 | 5001.1.1.44 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srv | 0.58 | 53.0 | 4.36e-01 | 98.2% | 90.8% |
| 3194196 | 633.23.1.22 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL | 0.58 | 40.0 | 4.35e-01 | 79.5% | 82.9% |
| 4946004 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 47.0 | 4.53e-01 | 91.0% | 96.8% |
| 3491432 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.56 | 40.0 | 4.08e-01 | 80.7% | 73.9% |
| 4213065 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.54 | 40.0 | 4.16e-01 | 80.1% | 79.4% |
| 3534658 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.54 | 40.0 | 4.15e-01 | 80.1% | 80.0% |
| 3886844 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.54 | 45.0 | 3.85e-01 | 90.4% | 83.6% |
| 3280790 | 601.1.2.127 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › LtrA | 0.54 | 42.0 | 4.00e-01 | 81.9% | 90.3% |
| 5036022 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.54 | 47.0 | 4.33e-01 | 95.8% | 88.1% |
| 3429223 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.54 | 38.0 | 3.95e-01 | 94.0% | 79.3% |
| 3232751 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.53 | 47.0 | 3.94e-01 | 95.8% | 89.8% |
| 4971806 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.53 | 39.0 | 3.63e-01 | 74.7% | 72.2% |
| 3996812 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.53 | 38.0 | 3.86e-01 | 80.7% | 75.0% |
| 3929335 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.52 | 47.0 | 4.21e-01 | 99.4% | 98.3% |
| 3523336 | 174.1.1.12 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › BCLP | 0.52 | 40.0 | 4.05e-01 | 80.1% | 82.4% |
| 3220199 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.52 | 39.0 | 4.09e-01 | 81.3% | 83.9% |
| 3416085 | 5001.1.1.50 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › DUF4791 | 0.52 | 45.0 | 4.30e-01 | 95.2% | 94.9% |
| 3924137 | 601.54.1.5 ↗ | alpha bundles › Four-helical up-and-down bundle › low CO2-inducible protein LCI1 › low CO2-inducible protein LCI1 › PF29123 | 0.51 | 39.0 | 4.15e-01 | 78.9% | 93.3% |
| 3801607 | 150.1.1.121 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › PF29123 | 0.51 | 39.0 | 4.10e-01 | 78.3% | 92.7% |
| 3617744 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.51 | 38.0 | 4.03e-01 | 81.3% | 85.3% |
| 3492033 | 5001.1.1.142 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › DUF716 | 0.51 | 46.0 | 4.08e-01 | 97.6% | 85.5% |
| 3733145 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.51 | 38.0 | 4.12e-01 | 80.1% | 91.4% |
| 5022737 | 1030.1.1.1 ↗ | alpha duplicates or obligate multimers › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Csm2_III-A | 0.51 | 48.0 | 4.78e-01 | 100.0% | 99.4% |
| 4376239 | 150.5.1.50 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › EspA_EspE | 0.51 | 39.0 | 3.44e-01 | 78.9% | 81.7% |
| 3394733 | 5001.1.1.50 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › DUF4791 | 0.51 | 44.0 | 4.25e-01 | 95.8% | 96.3% |
| 3283947 | 3352.1.1.0 ↗ | alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain | 0.51 | 44.0 | 3.34e-01 | 99.4% | 91.7% |
| 3214393 | 633.21.1.29 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › PF29123 | 0.51 | 39.0 | 4.07e-01 | 78.3% | 92.7% |