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OQ076693.1__WBM23473.1__X__00059

Bact-Vir

OQ076693.1__WBM23473.1__X__00059

Identity

Accession:
OQ076693 ↗
Kingdom:
phage

Quality

96.8 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-30_131-195
PDB
CATH (37)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1juvA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.95 92.0 6.99e-01 100.0% 100.0%
3ix9A00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.77 73.0 5.89e-01 100.0% 97.0%
2w9hA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.76 72.0 5.94e-01 100.0% 98.7%
1ao8A00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.76 70.0 5.77e-01 98.9% 98.1%
1bozA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.75 70.0 5.48e-01 100.0% 97.3%
6pf8A01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.75 70.0 5.56e-01 100.0% 97.7%
3k2hA01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.74 69.0 5.42e-01 100.0% 94.1%
4eckA01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.73 69.0 5.44e-01 100.0% 98.3%
1dhiA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.73 68.0 5.64e-01 100.0% 98.7%
2hxvA02 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.67 63.0 4.82e-01 100.0% 98.5%
1zpvA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.65 35.0 3.75e-01 100.0% 60.0%
3zpgA02 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.65 60.0 4.54e-01 100.0% 93.5%
2b3zA02 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.64 60.0 4.43e-01 100.0% 93.8%
3vcoA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.64 56.0 4.59e-01 100.0% 98.4%
2p4gA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.61 54.0 4.05e-01 100.0% 91.9%
2h2qB01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.61 57.0 4.27e-01 100.0% 88.2%
2aznA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.60 53.0 4.09e-01 100.0% 98.6%
3mwbB03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.59 35.0 3.56e-01 100.0% 60.0%
2go8A01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 31.0 3.52e-01 100.0% 67.6%
7dl8C01 3.30.110.20 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Alba-like domain 0.56 40.0 4.10e-01 88.4% 78.7%
2yqzA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 47.0 3.78e-01 100.0% 46.6%
1je3A01 3.30.110.40 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › TusA-like domain 0.55 40.0 4.41e-01 98.9% 100.0%
3b5iB01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 50.0 3.68e-01 100.0% 87.8%
2bkyX00 3.30.110.20 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Alba-like domain 0.54 44.0 4.63e-01 98.9% 96.5%
3fzgA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 42.0 3.34e-01 100.0% 40.8%
2efjA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 48.0 3.70e-01 100.0% 85.0%
4qdjA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 49.0 3.75e-01 100.0% 69.2%
3gnlA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 49.0 4.03e-01 100.0% 84.8%
3mtiB00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 47.0 3.84e-01 100.0% 86.7%
4u1qA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.52 43.0 3.49e-01 100.0% 46.0%
1tigA00 3.30.110.10 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Translation initiation factor 3 (IF-3), C-terminal domain 0.52 42.0 4.37e-01 100.0% 95.5%
5heeA00 3.40.830.10 Alpha Beta › 3-Layer(aba) Sandwich › Protocatechuate 4,5-dioxygenase; Chain B › LigB-like 0.52 46.0 3.39e-01 100.0% 99.2%
2vzyC00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.52 40.0 3.33e-01 100.0% 43.9%
3tmaA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 46.0 3.76e-01 100.0% 81.4%
1mhmA00 3.60.90.10 Alpha Beta › 4-Layer Sandwich › S-adenosylmethionine decarboxylase › S-adenosylmethionine decarboxylase 0.51 46.0 3.38e-01 100.0% 58.1%
8k5lA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.50 45.0 3.56e-01 100.0% 53.0%
4e2aA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.50 40.0 3.34e-01 100.0% 48.2%
ECOD (58)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
10266 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.95 92.0 6.99e-01 100.0% 100.0%
4315799 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.84 80.0 6.31e-01 100.0% 98.3%
137968 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.77 73.0 5.89e-01 100.0% 97.0%
3263045 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.77 72.0 5.52e-01 100.0% 94.0%
136031 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.77 71.0 5.34e-01 100.0% 98.1%
3963884 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.75 70.0 5.76e-01 100.0% 98.8%
3913441 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.74 69.0 5.35e-01 100.0% 96.3%
4402042 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.73 68.0 5.37e-01 100.0% 97.8%
3678575 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.70 38.0 5.01e-01 97.9% 94.5%
3382243 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.69 38.0 5.04e-01 97.9% 96.3%
3330441 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.69 37.0 4.24e-01 97.9% 69.3%
3820702 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.69 37.0 4.23e-01 97.9% 69.3%
3425342 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.69 37.0 4.22e-01 100.0% 69.3%
5027949 304.8.1.8 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_4 0.67 36.0 4.04e-01 100.0% 66.7%
2464384 2003.1.5.78 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_18 0.65 46.0 3.85e-01 100.0% 42.9%
3807253 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.65 39.0 4.29e-01 93.7% 72.5%
3365317 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.65 39.0 4.22e-01 92.6% 71.2%
4341311 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.65 35.0 3.65e-01 100.0% 57.8%
3371194 7501.1.1.0 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases 0.65 59.0 4.49e-01 100.0% 99.1%
3464409 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.64 36.0 4.10e-01 96.8% 72.0%
4977318 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.64 35.0 3.65e-01 100.0% 57.8%
4504111 304.8.1.2 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.64 34.0 3.74e-01 100.0% 63.7%
3365716 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.64 39.0 4.15e-01 93.7% 69.4%
4346339 304.8.1.2 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.63 34.0 3.74e-01 100.0% 63.7%
3456962 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.63 39.0 4.22e-01 92.6% 71.4%
3365659 304.8.1.1 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › Thr_dehydrat_C 0.63 33.0 3.47e-01 98.9% 54.4%
3660837 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.63 39.0 4.11e-01 92.6% 69.4%
5016388 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.63 35.0 3.71e-01 100.0% 62.4%
4952685 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.63 34.0 3.72e-01 100.0% 63.7%
4540169 304.8.1.8 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_4 0.63 35.0 3.73e-01 98.9% 62.4%
3302370 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.62 39.0 4.16e-01 92.6% 72.3%
3822278 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.62 39.0 4.10e-01 91.6% 70.6%
4206173 304.8.1.2 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.62 35.0 3.62e-01 100.0% 60.0%
5022986 304.113.1.0 a+b two layers › Alpha-beta plaits › Alpha subunit of glutamate synthase, insertion domain › Alpha subunit of glutamate synthase, insertion domain 0.61 34.0 3.69e-01 97.9% 65.0%
163852 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.61 54.0 4.05e-01 100.0% 91.9%
4994637 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.61 36.0 3.57e-01 98.9% 56.0%
3953555 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.61 54.0 4.37e-01 100.0% 97.9%
4464449 304.8.1.21 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_9 0.61 34.0 3.67e-01 97.9% 65.0%
4146323 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.60 35.0 3.77e-01 100.0% 65.9%
3317802 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.59 39.0 3.94e-01 91.6% 66.3%
4980571 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.59 51.0 3.97e-01 98.9% 99.5%
4041855 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.58 34.0 3.43e-01 100.0% 56.6%
3190333 2003.1.5.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.58 49.0 3.35e-01 100.0% 25.4%
4419286 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.58 39.0 4.01e-01 90.5% 71.0%
3608269 2003.1.5.73 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_16 0.57 46.0 3.24e-01 100.0% 27.4%
4980066 2003.1.5.81 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.55 46.0 3.63e-01 98.9% 44.7%
5001297 2003.1.5.5 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0020 0.55 50.0 4.01e-01 100.0% 80.5%
4941923 2003.1.5.5 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0020 0.54 49.0 3.76e-01 100.0% 79.5%
3833803 2003.1.5.115 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_29 0.54 49.0 3.23e-01 100.0% 36.5%
4958454 2003.1.5.81 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.54 49.0 3.81e-01 100.0% 75.5%
3807768 2003.1.5.115 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_29 0.54 49.0 3.48e-01 100.0% 53.5%
4932914 2003.1.5.5 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0020 0.54 49.0 3.92e-01 100.0% 81.1%
5035224 304.16.1.1 a+b two layers › Alpha-beta plaits › eEF-1beta-like › eEF-1beta-like › EF1_GNE 0.53 32.0 3.36e-01 100.0% 64.4%
3598257 2003.1.5.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.52 46.0 3.35e-01 100.0% 63.9%
3734045 2003.1.5.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.52 46.0 3.04e-01 100.0% 54.7%
5077347 2003.1.5.5 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0020 0.51 47.0 3.75e-01 100.0% 80.5%
3434168 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.51 42.0 4.06e-01 96.8% 79.0%
5073463 304.109.1.0 a+b two layers › Alpha-beta plaits › Ribosomal proteins S24e, L23 and L15e › Ribosomal proteins S24e, L23 and L15e 0.50 33.0 3.57e-01 91.6% 78.3%
D2 medium residues 31-130
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00186.25 best DHFR_1 51.9 9.50e-14 100.0% 49.1%
CATH (55)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1juvA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.97 94.0 7.21e-01 100.0% 51.3%
2w9hA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.86 61.0 5.12e-01 100.0% 46.5%
3ix9A00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.84 63.0 5.22e-01 100.0% 47.0%
1dhiA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.84 61.0 5.11e-01 100.0% 47.2%
5eccA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.82 61.0 5.12e-01 100.0% 49.0%
1cz3B00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.77 61.0 5.01e-01 100.0% 48.8%
1vdrA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.74 55.0 4.73e-01 100.0% 50.3%
6pf8A01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.70 60.0 4.82e-01 100.0% 50.6%
2h1qA02 3.40.50.11590 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.66 43.0 4.05e-01 100.0% 54.6%
3gygC01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.64 51.0 4.12e-01 86.0% 65.5%
5cm2Z00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.64 49.0 4.04e-01 100.0% 45.1%
1xjkA00 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.62 47.0 2.94e-01 82.0% 71.5%
3ihtA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.62 51.0 4.38e-01 100.0% 55.2%
3cc8A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.61 46.0 3.62e-01 99.0% 37.4%
4a27A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.61 52.0 4.47e-01 100.0% 59.0%
3ccfA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.61 46.0 3.49e-01 100.0% 33.2%
4necC01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.61 49.0 3.80e-01 100.0% 39.3%
3ofkA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.60 48.0 3.79e-01 100.0% 42.2%
1eamA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.60 53.0 3.82e-01 100.0% 34.4%
2wagA00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.59 50.0 3.93e-01 93.0% 46.1%
5l3qB02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 45.0 3.45e-01 81.0% 43.9%
2pjdA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 44.0 3.83e-01 100.0% 50.6%
2py6A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.59 45.0 4.30e-01 95.0% 68.3%
1rjgA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 52.0 3.79e-01 100.0% 60.1%
6ifsB01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 51.0 4.10e-01 100.0% 49.2%
2uyoA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 52.0 3.84e-01 100.0% 50.9%
1y8cA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 47.0 3.88e-01 100.0% 47.3%
2o6lB00 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.58 44.0 3.78e-01 82.0% 92.8%
5hvmA02 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.58 43.0 3.42e-01 94.0% 38.0%
5jioA02 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.58 42.0 3.37e-01 94.0% 37.3%
1ozhA02 3.40.50.1220 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain 0.57 49.0 4.24e-01 100.0% 61.0%
2bzgA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 51.0 3.91e-01 100.0% 46.3%
2a3nA01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.57 47.0 3.96e-01 92.0% 54.3%
3mteA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 43.0 3.37e-01 86.0% 37.0%
2pljA02 3.20.20.10 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase 0.57 50.0 3.89e-01 100.0% 96.9%
5wt3A03 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 47.0 3.87e-01 100.0% 49.7%
4rwzA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 43.0 3.46e-01 86.0% 41.5%
1u2zA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 42.0 3.49e-01 100.0% 43.9%
3jy6D02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.57 41.0 3.73e-01 79.0% 56.3%
3ll7A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 46.0 3.82e-01 100.0% 47.9%
3fbsA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.56 46.0 4.50e-01 95.0% 84.1%
1t57A00 3.40.1380.20 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › Pyruvate kinase, C-terminal domain 0.56 49.0 4.11e-01 100.0% 75.7%
2o57A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 48.0 4.12e-01 100.0% 59.4%
3knzA02 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.55 42.0 3.68e-01 100.0% 54.8%
4nesA02 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.55 43.0 3.66e-01 84.0% 91.4%
2b4yA01 3.40.50.1220 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain 0.55 46.0 4.08e-01 98.0% 62.5%
3fmgA01 3.40.50.11130 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycoprotein VP7, domain 1 0.54 45.0 3.96e-01 91.0% 62.2%
1d5rA01 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.53 41.0 3.45e-01 100.0% 47.7%
7f4oA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 46.0 3.75e-01 98.0% 78.1%
4xr7F02 1.10.287.3700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.53 37.0 3.86e-01 73.0% 94.4%
3htxD03 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.52 46.0 3.64e-01 100.0% 46.6%
3cq9A00 3.40.50.10240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin pyrophosphokinase, catalytic domain 0.52 41.0 3.31e-01 85.0% 45.0%
3pvlA05 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.52 31.0 3.49e-01 87.0% 77.6%
1xr4B01 3.40.1080.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaconate Coenzyme A-transferase › Glutaconate Coenzyme A-transferase 0.51 46.0 3.50e-01 100.0% 48.7%
1p5dX03 3.40.120.10 Alpha Beta › 3-Layer(aba) Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 3 › Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3 0.50 35.0 3.39e-01 100.0% 62.2%
ECOD (65)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
10266 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.97 94.0 7.21e-01 100.0% 51.3%
3963884 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.85 63.0 5.28e-01 100.0% 48.1%
2831687 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.84 61.0 4.97e-01 100.0% 43.4%
169540 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.84 62.0 5.12e-01 100.0% 45.8%
137968 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.84 63.0 5.22e-01 100.0% 47.0%
4563316 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.83 63.0 5.21e-01 100.0% 47.3%
2580403 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.83 59.0 4.80e-01 98.0% 41.7%
4276639 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.83 62.0 5.05e-01 100.0% 45.3%
4315799 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.83 65.0 5.23e-01 100.0% 46.3%
4624802 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.83 63.0 5.23e-01 100.0% 48.5%
4652224 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.83 61.0 5.04e-01 100.0% 46.3%
2847460 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.82 59.0 4.94e-01 100.0% 46.8%
1841334 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.82 59.0 5.10e-01 100.0% 50.3%
4295510 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.79 62.0 5.19e-01 100.0% 51.2%
4123104 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.77 60.0 5.00e-01 100.0% 49.7%
4209889 7501.1.1.0 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases 0.75 55.0 4.83e-01 100.0% 53.1%
4392683 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.74 59.0 4.94e-01 100.0% 50.9%
4965070 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.72 58.0 4.79e-01 100.0% 49.1%
4602940 2007.1.8.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Uroporphyrinogen III synthase (U3S, HemD) 0.69 51.0 5.15e-01 100.0% 77.0%
3263045 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.69 64.0 4.96e-01 100.0% 49.5%
4183099 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.67 59.0 4.80e-01 100.0% 52.2%
4977716 2003.1.5.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.65 44.0 3.91e-01 100.0% 48.3%
4318151 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.64 48.0 3.46e-01 100.0% 27.7%
3215298 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.63 47.0 3.57e-01 100.0% 32.0%
3516136 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.63 47.0 3.58e-01 100.0% 32.3%
3307924 2003.1.5.165 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11, Methyltransf_23 0.63 47.0 3.61e-01 100.0% 33.3%
None 0.63 47.0 3.63e-01 100.0% 34.0%
3921925 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.63 46.0 3.60e-01 100.0% 34.3%
3415491 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.63 46.0 3.43e-01 100.0% 28.7%
3580945 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.63 47.0 4.39e-01 100.0% 64.0%
4986416 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.62 50.0 3.75e-01 100.0% 35.1%
4026112 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.62 46.0 3.52e-01 100.0% 33.2%
4967032 2003.1.5.81 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.62 50.0 3.71e-01 100.0% 34.1%
5002185 2003.1.5.81 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.62 47.0 3.75e-01 99.0% 38.6%
3633600 2003.1.5.165 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11, Methyltransf_23 0.62 45.0 3.41e-01 100.0% 30.6%
3959323 2003.1.1.31 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › CbiJ 0.61 47.0 4.50e-01 100.0% 69.2%
3241616 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.61 45.0 3.32e-01 100.0% 27.9%
3817455 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.61 45.0 3.31e-01 100.0% 27.9%
3723928 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.61 45.0 3.44e-01 100.0% 32.0%
5000126 2003.1.5.81 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.61 47.0 4.12e-01 100.0% 53.5%
4952969 7509.1.1.1 a/b three-layered sandwiches › NIF3 (NGG1p interacting factor 3)-like › NIF3 (NGG1p interacting factor 3)-like › NIF3 (NGG1p interacting factor 3)-like › DUF34_NIF3 0.61 41.0 4.06e-01 86.0% 65.7%
3526266 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.61 45.0 3.45e-01 100.0% 32.2%
5027834 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.61 36.0 3.00e-01 85.0% 32.0%
3968398 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.60 41.0 3.26e-01 100.0% 32.3%
5037667 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.60 46.0 3.75e-01 100.0% 41.5%
3729104 2003.1.5.82 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31 0.60 48.0 3.53e-01 100.0% 32.0%
3220855 2003.1.5.73 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_16 0.58 52.0 4.21e-01 100.0% 54.2%
3249560 2006.1.1.3 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Trehalose_PPase 0.58 50.0 4.07e-01 98.0% 70.0%
3375545 7518.1.1.0 a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like 0.57 50.0 4.68e-01 100.0% 78.4%
5067350 7518.1.1.0 a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like 0.57 46.0 4.57e-01 98.0% 83.8%
146894 2003.1.5.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.56 46.0 3.72e-01 100.0% 44.2%
161556 2003.1.7.9 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › CitF 0.55 49.0 3.73e-01 99.0% 50.4%
4348495 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.55 49.0 3.72e-01 100.0% 49.8%
4030109 2006.1.4.12 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PIN_6 0.54 43.0 4.04e-01 86.0% 80.0%
3988268 2004.1.1.44 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PRK 0.54 48.0 3.80e-01 98.0% 92.2%
3559700 2003.1.5.134 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › DUF4470+DUF4471 0.54 45.0 3.20e-01 94.0% 74.6%
3277078 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.53 47.0 3.58e-01 100.0% 59.6%
5005349 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.52 40.0 2.62e-01 83.0% 23.4%
3972696 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.52 43.0 4.16e-01 94.0% 89.6%
4021707 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.51 46.0 3.43e-01 100.0% 41.2%
3193720 7524.1.1.1 a/b three-layered sandwiches › ALDH-like › ALDH-like › ALDH-like › Aldedh 0.51 41.0 3.23e-01 89.0% 78.3%
4182527 2003.1.5.68 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MTS_N 0.51 45.0 3.93e-01 100.0% 66.5%
5063790 2006.1.4.12 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PIN_6 0.51 40.0 3.76e-01 84.0% 80.0%
3636840 375.3.1.2 few secondary structure elements › Rubredoxin-like › CSL zinc finger › CSL zinc finger › zf-CSL 0.50 33.0 3.76e-01 76.0% 91.8%
3807514 2006.1.1.3 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Trehalose_PPase 0.50 42.0 3.06e-01 92.0% 61.8%