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OQ101250.1__WCF71567.1__Acba1_068__00055

Bact-Vir

OQ101250.1__WCF71567.1__Acba1_068__00055

Identity

Accession:
OQ101250 ↗
Kingdom:
phage

Quality

64.2 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 693-826
PDB
CATH (20)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1rl2A01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.69 29.0 4.27e-01 85.1% 91.1%
1z47A03 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.67 26.0 3.96e-01 99.3% 91.8%
2yf0A01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.61 39.0 4.76e-01 97.0% 100.0%
5jh8A02 3.10.50.10 Alpha Beta › Roll › Chitinase A; domain 3 › 0.60 28.0 3.75e-01 81.3% 85.1%
1eigA00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.60 28.0 3.70e-01 85.1% 80.8%
3cz8A02 3.10.50.10 Alpha Beta › Roll › Chitinase A; domain 3 › 0.58 27.0 3.85e-01 74.6% 100.0%
3pvlA04 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.57 39.0 4.49e-01 97.8% 94.9%
1icwB00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.56 28.0 3.87e-01 86.6% 97.0%
3fssA02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.56 35.0 4.25e-01 97.8% 96.5%
4ok4A02 2.70.98.70 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.55 41.0 3.04e-01 77.6% 62.9%
4tyzA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.55 39.0 4.25e-01 100.0% 89.0%
4hcsA00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.54 28.0 3.73e-01 81.3% 97.0%
5xbfA03 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.53 35.0 4.13e-01 99.3% 100.0%
3a8pB01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.53 41.0 4.44e-01 100.0% 94.8%
3lxuX02 2.20.25.690 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.52 24.0 3.14e-01 88.8% 79.2%
1bakA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.51 37.0 3.89e-01 97.8% 84.0%
3f5rA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.50 37.0 4.01e-01 97.0% 90.3%
4fnfA00 2.40.50.50 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.50 30.0 3.38e-01 100.0% 78.6%
3fm2A00 3.40.1570.10 Alpha Beta › 3-Layer(aba) Sandwich › Heme iron utilization protein-like fold › HemS/ChuS/ChuX like domains 0.50 44.0 4.45e-01 100.0% 95.5%
2eyqA05 2.40.10.170 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.50 23.0 3.19e-01 99.3% 93.2%
ECOD (28)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5022340 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.63 32.0 4.19e-01 99.3% 90.0%
4500525 284.2.1.0 a+b two layers › FKBP-like › Chitinase insertion domain › Chitinase insertion domain 0.59 27.0 3.79e-01 74.6% 100.0%
3259095 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.58 39.0 4.16e-01 100.0% 77.5%
3893746 220.1.1.8 beta barrels › PH domain-like › PH domain-like › PH domain-like › GRAM 0.56 41.0 4.07e-01 100.0% 70.7%
3627778 220.1.1.64 beta barrels › PH domain-like › PH domain-like › PH domain-like › FERM_C1_MyoVII 0.56 39.0 4.38e-01 98.5% 94.0%
4949942 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.56 35.0 4.24e-01 94.8% 96.6%
3567875 220.1.1.8 beta barrels › PH domain-like › PH domain-like › PH domain-like › GRAM 0.56 41.0 3.89e-01 100.0% 63.7%
3270836 220.1.1.8 beta barrels › PH domain-like › PH domain-like › PH domain-like › GRAM 0.55 38.0 4.11e-01 100.0% 82.6%
3890418 220.1.1.38 beta barrels › PH domain-like › PH domain-like › PH domain-like › UCH_N 0.55 41.0 4.62e-01 99.3% 100.0%
3596312 220.1.1.8 beta barrels › PH domain-like › PH domain-like › PH domain-like › GRAM 0.55 39.0 3.99e-01 100.0% 75.4%
3924612 220.1.1.8 beta barrels › PH domain-like › PH domain-like › PH domain-like › GRAM 0.54 38.0 3.82e-01 100.0% 71.1%
3721377 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.54 40.0 4.20e-01 99.3% 85.8%
3810543 220.1.1.20 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_TFIIH 0.54 38.0 4.18e-01 97.8% 89.1%
3233725 220.1.1.8 beta barrels › PH domain-like › PH domain-like › PH domain-like › GRAM 0.54 38.0 3.64e-01 100.0% 61.3%
3241979 220.1.1.7 beta barrels › PH domain-like › PH domain-like › PH domain-like › IRS 0.54 37.0 4.13e-01 97.8% 90.5%
4203238 220.1.1.217 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH, GRAM 0.54 38.0 3.10e-01 100.0% 38.4%
3619467 220.1.1.84 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_15 0.53 39.0 4.24e-01 94.0% 90.9%
3768329 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.53 38.0 3.97e-01 97.8% 80.0%
3927128 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.53 40.0 4.21e-01 96.3% 88.3%
4674129 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.53 37.0 4.12e-01 100.0% 92.4%
3914585 220.1.1.1 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.52 36.0 4.07e-01 94.8% 91.4%
3234621 220.1.1.8 beta barrels › PH domain-like › PH domain-like › PH domain-like › GRAM 0.52 39.0 3.93e-01 100.0% 77.0%
3555736 220.1.1.1 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.52 37.0 3.61e-01 99.3% 66.0%
3700838 220.1.1.8 beta barrels › PH domain-like › PH domain-like › PH domain-like › GRAM 0.52 39.0 3.99e-01 100.0% 80.8%
4093535 220.1.1.1 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.51 37.0 3.78e-01 99.3% 76.2%
3907293 220.1.1.1 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.51 36.0 4.06e-01 97.0% 93.3%
3929135 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.51 37.0 4.06e-01 100.0% 97.1%
3496244 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.50 40.0 4.02e-01 100.0% 82.1%
D2 high residues 856-877_879-895_898-914
PDB
Domain cluster: representative
CATH (32)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5wp3B00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.92 83.0 6.64e-01 96.4% 54.9%
3besR03 6.10.140.1480 Special › Helix non-globular › Helix Hairpins › 0.87 66.0 6.61e-01 80.4% 83.9%
4kp3C00 1.20.58.1770 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.81 72.0 6.36e-01 100.0% 72.8%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.80 70.0 6.27e-01 98.2% 82.1%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.79 71.0 5.18e-01 100.0% 47.6%
2f93B00 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.78 61.0 6.36e-01 89.3% 94.1%
4fzwA02 1.10.12.10 Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 0.78 54.0 5.41e-01 73.2% 72.4%
1tmxB00 2.60.130.10 Mainly Beta › Sandwich › Protocatechuate 3,4-Dioxygenase, subunit A › Aromatic compound dioxygenase 0.78 58.0 3.59e-01 78.6% 15.7%
2yevC00 6.10.280.110 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 67.0 6.42e-01 94.6% 90.5%
7vkcA01 1.10.1070.20 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › 0.77 54.0 3.79e-01 73.2% 26.7%
2ig3A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.77 62.0 4.68e-01 89.3% 38.6%
4jylA02 1.10.12.10 Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 0.75 51.0 5.33e-01 71.4% 85.7%
4di1C02 1.10.12.10 Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 0.74 51.0 5.63e-01 73.2% 100.0%
3vm9A02 6.10.140.2110 Special › Helix non-globular › Helix Hairpins › 0.74 57.0 5.76e-01 87.5% 91.2%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.73 55.0 4.58e-01 89.3% 48.4%
6r1nA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.72 63.0 5.17e-01 98.2% 62.1%
3zgxA02 6.10.140.1720 Special › Helix non-globular › Helix Hairpins › 0.72 63.0 5.34e-01 98.2% 75.8%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.72 63.0 5.71e-01 100.0% 75.3%
1st6A03 1.20.120.810 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle 0.72 60.0 4.03e-01 96.4% 24.5%
5c9gA02 1.10.12.10 Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 0.69 51.0 5.08e-01 78.6% 78.9%
2r9iA00 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.69 60.0 5.59e-01 100.0% 98.6%
1x4tA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.68 55.0 5.47e-01 87.5% 87.9%
2qf9A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.67 52.0 3.87e-01 87.5% 33.3%
8fbnB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.67 59.0 3.96e-01 100.0% 25.7%
2btqB03 1.10.287.600 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.66 51.0 5.30e-01 85.7% 96.2%
5b1aC01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 55.0 5.19e-01 94.6% 80.9%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 54.0 5.01e-01 100.0% 82.2%
1zhcA00 6.10.280.50 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 50.0 4.66e-01 96.4% 85.5%
1b04A03 1.10.287.610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.60 41.0 4.03e-01 71.4% 80.6%
2lf0A01 4.10.860.10 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain 0.57 42.0 4.12e-01 76.8% 80.0%
2oy9A01 1.10.220.80 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › BH2638-like 0.53 39.0 3.55e-01 78.6% 69.7%
4uqfG01 1.10.286.10 Mainly Alpha › Orthogonal Bundle › GTP Cyclohydrolase I; Chain A, domain 1 › GTP cyclohydrolase I, N-terminal domain 0.52 41.0 4.18e-01 96.4% 100.0%
ECOD (22)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3879791 378.1.1.0 few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases 0.88 72.0 4.66e-01 87.5% 22.7%
197868 614.1.1.0 alpha duplicates or obligate multimers › L27 domain › L27 domain › L27 domain 0.87 66.0 6.85e-01 80.4% 92.2%
3626992 632.8.1.2 alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › Alpha-2-MRAP_C 0.85 72.0 5.81e-01 92.9% 52.4%
1070875 3726.1.1.1 alpha bundles › RILP-like protein 2 N-terminal helical hairpin domain › RILP-like protein 2 N-terminal helical hairpin domain › RILP-like protein 2 N-terminal helical hairpin domain › RH1 0.84 76.0 6.65e-01 100.0% 73.2%
3909706 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.83 76.0 6.55e-01 100.0% 65.9%
4323124 109.3.1.2 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.81 62.0 3.81e-01 83.9% 14.8%
4942548 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.80 62.0 4.51e-01 83.9% 34.0%
4038742 150.5.1.53 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PPE 0.77 69.0 5.77e-01 100.0% 63.2%
4831662 5043.1.1.1 extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like › Htr2 0.76 62.0 5.95e-01 94.6% 77.3%
3293973 708.1.2.1 beta complex topology › ETN0001 domain-like › ETN0001 domain-like › Mss4-like › TCTP 0.75 54.0 4.51e-01 78.6% 44.0%
3619435 192.8.1.36 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › M_domain 0.74 66.0 5.47e-01 98.2% 89.5%
3613914 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.73 65.0 5.89e-01 98.2% 78.7%
3973453 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.73 64.0 5.67e-01 98.2% 73.8%
4010395 622.4.1.26 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › HisKA 0.71 59.0 5.47e-01 91.1% 74.3%
3982421 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.70 62.0 5.57e-01 96.4% 73.3%
3685099 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.70 57.0 5.51e-01 91.1% 80.0%
3486248 6132.1.1.0 alpha bundles › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain 0.70 51.0 4.88e-01 76.8% 72.3%
2081586 616.1.1.1 alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › Ribosomal_S15 0.68 53.0 5.11e-01 82.1% 83.9%
3820045 603.1.1.118 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF7610 0.68 54.0 4.71e-01 87.5% 61.2%
3927737 632.8.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 0.66 56.0 4.73e-01 94.6% 93.7%
5047626 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.65 57.0 4.43e-01 100.0% 50.4%
3704 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.64 52.0 4.80e-01 89.3% 75.0%
D3 medium residues 61-118
PDB
D4 medium residues 119-265
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF20155.5 best TMP_3 176.7 6.20e-52 100.0% 76.0%
D5 medium residues 325-397
PDB
D6 medium residues 438-612
PDB
Domain cluster: representative
CATH (29)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1vctA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.70 35.0 4.34e-01 73.1% 76.1%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.69 37.0 4.48e-01 76.0% 77.1%
2gscC00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.68 30.0 3.81e-01 74.3% 67.3%
3mpxA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.67 49.0 4.62e-01 73.7% 95.1%
4yonA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.67 48.0 4.45e-01 73.1% 92.1%
3jrtA00 1.20.120.1060 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.63 35.0 3.67e-01 71.4% 57.8%
8etcb01 1.20.120.1190 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.62 36.0 3.96e-01 73.7% 67.8%
2rdcA00 1.10.287.800 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 0.62 35.0 4.04e-01 82.9% 72.9%
6grjB01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.62 45.0 3.62e-01 74.3% 72.4%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.61 44.0 4.82e-01 73.7% 99.3%
2x1lA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.61 38.0 3.86e-01 88.0% 62.2%
2fonA04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.60 30.0 3.41e-01 73.7% 62.0%
3vhlA02 1.20.58.740 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DOCK DHR2 domain, lobe C 0.59 37.0 4.32e-01 81.1% 90.0%
1txdA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.59 48.0 4.35e-01 85.7% 92.6%
6tblB01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.58 30.0 3.62e-01 82.9% 74.8%
2j1dG01 1.20.58.2220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Formin, FH2 domain 0.57 40.0 3.19e-01 71.4% 68.0%
1st6A04 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.56 31.0 3.72e-01 77.1% 80.3%
4cybD00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.56 43.0 4.44e-01 80.6% 87.7%
2pfdA03 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.55 45.0 4.32e-01 85.7% 89.7%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 36.0 3.86e-01 85.1% 74.7%
3u64A00 1.25.40.920 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TRAP transporter T-component 0.55 48.0 4.13e-01 93.1% 77.5%
1ldjA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.54 33.0 3.89e-01 76.6% 88.7%
2felA00 1.20.200.10 Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) 0.54 43.0 3.41e-01 81.1% 89.9%
7cj3A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.54 33.0 2.94e-01 85.7% 40.7%
8d7hD01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.54 36.0 3.70e-01 70.3% 69.4%
6tkyA03 1.20.58.740 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DOCK DHR2 domain, lobe C 0.53 35.0 4.06e-01 80.0% 94.3%
4udsA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 45.0 4.42e-01 90.3% 90.0%
2o6yA02 1.20.200.10 Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) 0.53 42.0 3.45e-01 83.4% 66.1%
1nigA00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.50 38.0 4.13e-01 82.9% 93.8%
ECOD (33)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4020294 603.1.1.1 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin 0.73 53.0 4.85e-01 74.3% 76.4%
5018948 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.70 35.0 4.30e-01 73.1% 74.5%
4337796 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.69 34.0 3.70e-01 74.3% 54.0%
3855165 604.6.1.65 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT, GGA_N-GAT 0.68 33.0 3.85e-01 73.1% 63.8%
4983442 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.68 34.0 4.47e-01 73.1% 87.4%
3495843 1203.1.2.0 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 0.66 46.0 4.51e-01 71.4% 95.9%
3721326 5001.1.1.85 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin 0.66 46.0 3.97e-01 70.9% 67.8%
3826941 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.65 46.0 4.65e-01 72.6% 97.8%
4936312 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.65 34.0 4.23e-01 73.1% 80.9%
3792413 150.1.1.89 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › TRAM_LAG1_CLN8 0.62 38.0 3.44e-01 84.0% 44.8%
3940940 3755.3.1.288 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › LMBR1 0.62 41.0 4.80e-01 70.3% 92.8%
3798265 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.61 44.0 4.27e-01 74.3% 66.7%
5071763 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.60 33.0 3.51e-01 74.9% 58.2%
4942097 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.59 43.0 3.95e-01 74.3% 74.5%
3609126 6155.1.1.0 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter 0.59 30.0 3.52e-01 84.6% 68.3%
3866338 133.1.1.1 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.58 46.0 4.26e-01 82.9% 88.2%
5062266 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.58 34.0 3.66e-01 72.6% 66.0%
3988607 1075.1.2.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.57 33.0 3.50e-01 86.3% 62.7%
3213375 5001.1.1.44 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srv 0.56 42.0 3.47e-01 86.3% 45.5%
4025954 3758.1.1.0 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.55 45.0 3.99e-01 85.1% 78.4%
3743077 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.55 37.0 4.34e-01 85.1% 95.2%
3315414 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.55 39.0 3.90e-01 71.4% 85.6%
3610580 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.55 33.0 3.59e-01 73.1% 70.7%
3249527 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.55 35.0 3.96e-01 84.6% 82.2%
3741090 5069.1.1.39 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Glucan_synthase 0.55 43.0 3.90e-01 81.7% 88.5%
3690615 6155.1.1.2 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.54 30.0 3.52e-01 80.6% 74.6%
5080472 3834.1.1.0 alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain 0.53 38.0 2.71e-01 73.1% 84.9%
4032308 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.52 38.0 3.85e-01 83.4% 75.3%
3444721 603.1.1.6 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 0.52 38.0 3.65e-01 73.7% 86.7%
5028679 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.51 26.0 3.41e-01 92.6% 85.4%
3582450 5054.1.1.17 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TRAM_LAG1_CLN8 0.51 37.0 3.26e-01 74.9% 69.8%
3907440 603.1.1.103 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF29732 0.51 39.0 3.98e-01 80.6% 86.3%
3608506 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.50 40.0 3.52e-01 83.4% 78.0%
D7 medium residues 613-692
PDB
D8 medium residues 1068-1154
PDB
Domain cluster: representative
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1yc9A01 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.88 66.0 4.33e-01 78.2% 20.8%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.84 69.0 5.47e-01 87.4% 46.6%
6grjB01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.80 73.0 4.82e-01 98.9% 26.9%
6iknD01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.77 71.0 4.94e-01 100.0% 36.0%
1t98A02 1.20.58.590 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain 0.75 58.0 4.66e-01 83.9% 43.6%
7qx4A01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.72 48.0 3.48e-01 77.0% 25.2%
3vkgA02 1.20.140.100 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain 0.70 47.0 3.96e-01 70.1% 42.2%
3anwB00 1.20.58.2050 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 44.0 3.59e-01 71.3% 51.2%
3craA02 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.57 42.0 3.73e-01 78.2% 80.5%
4in3B00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.56 47.0 2.82e-01 90.8% 69.3%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3968781 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.89 68.0 5.52e-01 78.2% 46.9%
3770290 4177.1.1.41 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › EVC2_like 0.89 72.0 5.37e-01 86.2% 37.9%
4362095 1073.1.1.42 alpha arrays › Mitochondrial calcium uniporter (MCU) › Mitochondrial calcium uniporter (MCU) › Mitochondrial calcium uniporter (MCU) › EVC2_like 0.87 70.0 5.18e-01 85.1% 36.1%
3242106 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.86 66.0 5.75e-01 82.8% 56.0%
3913300 3755.3.1.303 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A_4th 0.84 62.0 5.03e-01 75.9% 45.3%
3404270 377.1.1.0 few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like 0.84 74.0 6.41e-01 100.0% 63.8%
3410594 4177.1.1.6 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3_WASP_bdg 0.81 74.0 5.57e-01 100.0% 42.4%
5030599 192.15.1.226 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › CdvA 0.79 67.0 5.81e-01 92.0% 60.8%
4942387 632.7.1.66 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › DUF2304 0.78 57.0 5.22e-01 75.9% 71.8%
None 0.78 67.0 4.59e-01 97.7% 28.6%
3506288 4177.1.1.6 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3_WASP_bdg 0.77 69.0 5.15e-01 98.9% 93.0%
3601851 1075.4.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold 0.77 56.0 4.08e-01 78.2% 29.1%
4231910 4168.1.1.1 alpha duplicates or obligate multimers › HAMP domain › HAMP domain › HAMP domain › HAMP 0.75 63.0 5.81e-01 89.7% 94.5%
3740499 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.74 67.0 4.93e-01 100.0% 48.0%
3743463 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.74 66.0 4.93e-01 100.0% 49.5%
3931480 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.73 49.0 4.86e-01 70.1% 65.6%
4975841 192.15.1.0 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.68 50.0 4.73e-01 81.6% 65.4%
4076608 109.4.1.924 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_CcmH_CycH 0.65 57.0 3.99e-01 100.0% 34.9%