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OQ221560.1__WCS67439.1__PhiCrAssBcn25_58__00058
Bact-VirOQ221560.1__WCS67439.1__PhiCrAssBcn25_58__00058
Identity
- Accession:
- OQ221560 ↗
- Kingdom:
- phage
Quality
74.5
mean pLDDT
Taxonomy
Heunggongvirae›
Uroviricota›
Caudoviricetes›
Crassvirales›
Steigviridae›
Bacteroides_phage_PhiCrAssBcn25
TaxID: 3023108
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 23-145
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF25712.2 best | crAss_CARGO2 | 219.2 | 1.90e-64 | 100.0% | 22.6% |
CATH (35)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3m7gA02 | 1.10.8.1010 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.78 | 54.0 | 6.11e-01 | 71.5% | 96.8% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.75 | 52.0 | 4.88e-01 | 71.5% | 81.5% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.75 | 53.0 | 5.43e-01 | 73.2% | 78.3% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.74 | 55.0 | 5.22e-01 | 77.2% | 74.6% |
| 3rfyA02 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.72 | 49.0 | 5.24e-01 | 97.6% | 80.4% |
| 1x8zB00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.71 | 51.0 | 4.84e-01 | 74.0% | 66.0% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.71 | 50.0 | 4.69e-01 | 73.2% | 66.7% |
| 1gvnA00 | 1.10.8.130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.71 | 49.0 | 5.68e-01 | 74.0% | 100.0% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.70 | 51.0 | 5.13e-01 | 74.8% | 82.8% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.70 | 65.0 | 5.30e-01 | 100.0% | 78.8% |
| 4fz4A00 | 1.20.140.130 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.68 | 56.0 | 5.17e-01 | 100.0% | 69.5% |
| 1uruA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.68 | 56.0 | 4.68e-01 | 88.6% | 93.8% |
| 2ficB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.66 | 57.0 | 4.76e-01 | 91.9% | 95.0% |
| 8a1gC01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.65 | 48.0 | 4.25e-01 | 78.0% | 93.4% |
| 7zdtD01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.65 | 48.0 | 3.54e-01 | 78.0% | 60.1% |
| 7s0rB01 | 1.20.81.20 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › | 0.64 | 40.0 | 4.81e-01 | 95.9% | 100.0% |
| 1tjoB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.64 | 53.0 | 4.74e-01 | 90.2% | 90.9% |
| 7cfmR01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.63 | 51.0 | 3.94e-01 | 84.6% | 51.3% |
| 4dylA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.63 | 44.0 | 3.51e-01 | 71.5% | 72.0% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.62 | 44.0 | 4.66e-01 | 87.0% | 83.3% |
| 1v9vA01 | 1.20.1480.20 | Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › MAST3 pre-PK domain-like | 0.61 | 40.0 | 4.45e-01 | 95.9% | 84.2% |
| 7akwA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 53.0 | 4.31e-01 | 92.7% | 100.0% |
| 1a5tA03 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.61 | 40.0 | 4.19e-01 | 91.9% | 71.6% |
| 5xfaA04 | 1.20.1440.230 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain | 0.61 | 34.0 | 3.96e-01 | 83.7% | 77.6% |
| 3s84A02 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.61 | 46.0 | 4.30e-01 | 80.5% | 72.0% |
| 1wdzA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.59 | 47.0 | 3.89e-01 | 86.2% | 94.4% |
| 4nooB00 | 1.10.8.1160 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.59 | 42.0 | 4.65e-01 | 91.9% | 96.8% |
| 3pltA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.59 | 51.0 | 4.36e-01 | 100.0% | 95.3% |
| 4yjwA00 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.58 | 45.0 | 4.20e-01 | 82.1% | 73.9% |
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.58 | 44.0 | 3.41e-01 | 79.7% | 67.5% |
| 3t9oB00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.57 | 43.0 | 4.39e-01 | 97.6% | 80.0% |
| 2bl2A00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.54 | 48.0 | 4.47e-01 | 100.0% | 86.5% |
| 2ipcA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.54 | 41.0 | 3.23e-01 | 78.9% | 86.8% |
| 1xwmA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.54 | 44.0 | 3.73e-01 | 99.2% | 51.9% |
| 7c4sB01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 45.0 | 3.50e-01 | 97.6% | 43.8% |
ECOD (39)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3568926 | 7515.1.1.6 ↗ | a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like › Phosphodiest | 0.78 | 55.0 | 3.73e-01 | 85.4% | 22.0% |
| 4591251 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.77 | 52.0 | 6.11e-01 | 91.9% | 100.0% |
| 4679869 | 632.15.1.4 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › HSP70 | 0.77 | 52.0 | 6.11e-01 | 91.9% | 100.0% |
| 3255242 | 601.1.2.4 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_R4 | 0.77 | 57.0 | 5.17e-01 | 76.4% | 63.7% |
| 5036993 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.76 | 54.0 | 6.14e-01 | 73.2% | 100.0% |
| 3424034 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.75 | 52.0 | 4.85e-01 | 70.7% | 65.3% |
| 3609516 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.75 | 60.0 | 5.32e-01 | 84.6% | 96.0% |
| 3793073 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.75 | 60.0 | 6.32e-01 | 87.8% | 93.6% |
| 1225266 | 605.4.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › Rop | 0.75 | 52.0 | 6.06e-01 | 95.9% | 100.0% |
| 5001811 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.74 | 53.0 | 6.12e-01 | 87.0% | 100.0% |
| 4103507 | 632.22.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA | 0.72 | 52.0 | 5.85e-01 | 75.6% | 100.0% |
| 3486497 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.72 | 52.0 | 5.15e-01 | 75.6% | 78.5% |
| 3433323 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.72 | 59.0 | 5.59e-01 | 87.0% | 75.2% |
| 3290567 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.71 | 51.0 | 5.44e-01 | 73.2% | 100.0% |
| 5001019 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.71 | 60.0 | 5.32e-01 | 90.2% | 94.7% |
| 3435434 | 632.1.1.13 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Rx_N | 0.70 | 55.0 | 5.94e-01 | 91.1% | 96.2% |
| 4971764 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.70 | 56.0 | 4.77e-01 | 87.0% | 76.1% |
| 3731546 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.68 | 57.0 | 5.12e-01 | 90.2% | 81.8% |
| 3267567 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.68 | 50.0 | 5.23e-01 | 77.2% | 92.7% |
| 3239453 | 601.1.2.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin | 0.67 | 52.0 | 5.04e-01 | 100.0% | 73.3% |
| 3231234 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.67 | 56.0 | 5.51e-01 | 92.7% | 84.6% |
| 3737781 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.66 | 37.0 | 4.02e-01 | 72.4% | 63.8% |
| 4357809 | 604.12.1.4 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › ATG1-like_MIT1 | 0.66 | 46.0 | 4.21e-01 | 71.5% | 72.5% |
| 3880538 | 632.1.1.28 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › DUF2678 | 0.66 | 45.0 | 5.30e-01 | 88.6% | 100.0% |
| 4980864 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.65 | 40.0 | 4.04e-01 | 70.7% | 61.0% |
| 3629560 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.65 | 55.0 | 5.13e-01 | 91.9% | 78.1% |
| 3806150 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.65 | 46.0 | 4.93e-01 | 98.4% | 86.7% |
| 3393821 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.64 | 57.0 | 5.26e-01 | 95.1% | 75.5% |
| 3526138 | 5054.1.1.2 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans | 0.64 | 47.0 | 3.54e-01 | 76.4% | 74.1% |
| 4944676 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.63 | 54.0 | 5.55e-01 | 95.9% | 96.5% |
| 3603460 | 109.4.1.1877 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, ANAPC3, TPR_8, TPR_16 | 0.63 | 52.0 | 3.83e-01 | 89.4% | 42.8% |
| 3832044 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.62 | 53.0 | 5.52e-01 | 97.6% | 98.3% |
| 4213065 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.62 | 57.0 | 5.18e-01 | 99.2% | 76.2% |
| 3174776 | 4177.1.1.5 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 | 0.61 | 47.0 | 3.81e-01 | 80.5% | 77.3% |
| 3996812 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.61 | 52.0 | 4.84e-01 | 95.9% | 76.9% |
| 5047547 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.58 | 36.0 | 3.76e-01 | 74.8% | 66.1% |
| 3470630 | 5054.1.1.2 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans | 0.57 | 50.0 | 3.67e-01 | 94.3% | 76.9% |
| 5077194 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.56 | 43.0 | 4.41e-01 | 91.9% | 82.4% |
| 3251359 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.51 | 46.0 | 4.13e-01 | 100.0% | 78.9% |
D2
high
residues 153-255
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF25712.2 best | crAss_CARGO2 | 150.0 | 1.70e-43 | 100.0% | 18.8% |
CATH (28)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3fblA00 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 42.0 | 4.61e-01 | 97.1% | 75.6% |
| 8e9gE01 | 1.10.10.1590 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › NADH-quinone oxidoreductase subunit E | 0.69 | 36.0 | 4.39e-01 | 95.1% | 81.0% |
| 3f2eA00 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 39.0 | 4.24e-01 | 100.0% | 69.9% |
| 3h36A00 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.64 | 44.0 | 4.89e-01 | 99.0% | 93.6% |
| 1txuA01 | 1.10.246.120 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.63 | 42.0 | 4.42e-01 | 100.0% | 75.5% |
| 2hroA02 | 1.10.274.10 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain | 0.59 | 42.0 | 3.90e-01 | 72.8% | 86.7% |
| 1wkbA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.59 | 33.0 | 3.14e-01 | 92.2% | 45.5% |
| 1xd4A04 | 1.10.840.10 | Mainly Alpha › Orthogonal Bundle › Son of Sevenless (SoS) protein; Chain S, domain 2 › Ras guanine-nucleotide exchange factors catalytic domain | 0.59 | 37.0 | 2.93e-01 | 100.0% | 30.3% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.59 | 35.0 | 3.95e-01 | 90.3% | 78.2% |
| 1f5oA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.58 | 40.0 | 3.61e-01 | 78.6% | 49.7% |
| 2d9dA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.57 | 39.0 | 4.14e-01 | 100.0% | 79.8% |
| 1zymA02 | 1.10.274.10 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain | 0.57 | 40.0 | 3.80e-01 | 73.8% | 88.1% |
| 3onjA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.56 | 33.0 | 3.40e-01 | 96.1% | 60.8% |
| 1ki1B01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.55 | 45.0 | 3.68e-01 | 89.3% | 87.4% |
| 3fp3A01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.55 | 29.0 | 2.70e-01 | 100.0% | 37.8% |
| 1vsgA02 | 1.10.470.10 | Mainly Alpha › Orthogonal Bundle › Variant Surface Glycoprotein, subunit A; domain 2 › Variant Surface Glycoprotein, subunit A, domain 2 | 0.55 | 44.0 | 3.80e-01 | 96.1% | 56.0% |
| 1rtwB00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.55 | 43.0 | 3.39e-01 | 100.0% | 41.3% |
| 2yb5F01 | 1.20.1280.250 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.54 | 34.0 | 3.65e-01 | 100.0% | 73.3% |
| 5kbwB00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.54 | 47.0 | 4.03e-01 | 98.1% | 76.0% |
| 3iqtA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.53 | 43.0 | 4.26e-01 | 92.2% | 95.6% |
| 3p5nA00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.52 | 45.0 | 3.91e-01 | 98.1% | 78.6% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.52 | 42.0 | 4.08e-01 | 89.3% | 99.1% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.52 | 40.0 | 4.13e-01 | 83.5% | 99.0% |
| 2rd3D00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.52 | 41.0 | 3.21e-01 | 100.0% | 40.4% |
| 4nwpD00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.51 | 43.0 | 3.80e-01 | 92.2% | 80.5% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.51 | 45.0 | 4.34e-01 | 99.0% | 87.2% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.51 | 38.0 | 3.70e-01 | 78.6% | 100.0% |
| 5vbfA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.50 | 43.0 | 3.15e-01 | 96.1% | 66.7% |
ECOD (26)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4565043 | 3718.1.1.0 ↗ | alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT | 0.62 | 31.0 | 3.34e-01 | 94.2% | 54.4% |
| 3404501 | 706.1.1.2 ↗ | beta complex topology › Head domain of nucleotide exchange factor GrpE › Head domain of nucleotide exchange factor GrpE › Head domain of nucleotide exchange factor GrpE › MIEAP | 0.62 | 56.0 | 4.52e-01 | 100.0% | 54.4% |
| 3163928 | 1075.5.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt | 0.58 | 36.0 | 3.00e-01 | 80.6% | 32.8% |
| 4530307 | 607.1.1.1 ↗ | alpha arrays › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › PEP-utilisers_N | 0.58 | 41.0 | 3.87e-01 | 72.8% | 88.8% |
| 3284120 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.58 | 45.0 | 3.71e-01 | 83.5% | 91.8% |
| 5061092 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.58 | 45.0 | 3.77e-01 | 83.5% | 96.7% |
| 3775315 | 7071.1.1.0 ↗ | 0.58 | 43.0 | 3.12e-01 | 92.2% | 27.0% | |
| 4490103 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.58 | 45.0 | 3.72e-01 | 83.5% | 96.8% |
| 4200315 | 604.6.1.59 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › PigN | 0.57 | 46.0 | 4.25e-01 | 87.4% | 91.9% |
| 3285240 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.57 | 45.0 | 3.59e-01 | 83.5% | 86.8% |
| 4927302 | 1075.1.2.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain | 0.57 | 46.0 | 4.20e-01 | 100.0% | 64.3% |
| 4078970 | 607.1.1.1 ↗ | alpha arrays › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › PEP-utilisers_N | 0.56 | 40.0 | 3.66e-01 | 73.8% | 79.3% |
| 4648748 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.55 | 44.0 | 3.59e-01 | 86.4% | 90.5% |
| 3291371 | 5050.1.1.60 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_3 | 0.55 | 46.0 | 3.78e-01 | 92.2% | 92.3% |
| 3972329 | 633.5.1.0 ↗ | alpha bundles › Bromodomain-like › LemA-like › LemA-like | 0.54 | 44.0 | 3.85e-01 | 89.3% | 86.7% |
| 3514777 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.54 | 42.0 | 3.82e-01 | 83.5% | 85.7% |
| 5050413 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.53 | 41.0 | 3.43e-01 | 85.4% | 90.0% |
| 3730615 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.53 | 43.0 | 3.20e-01 | 88.3% | 61.5% |
| 3415173 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.53 | 41.0 | 3.25e-01 | 83.5% | 78.7% |
| 3481178 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.53 | 43.0 | 3.85e-01 | 90.3% | 86.7% |
| 4947298 | 4323.1.1.1 ↗ | alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › V_ATPase_I | 0.53 | 32.0 | 3.06e-01 | 91.3% | 50.4% |
| 3387249 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 44.0 | 3.61e-01 | 94.2% | 88.7% |
| 4008800 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 42.0 | 3.33e-01 | 89.3% | 77.3% |
| 3742987 | 5045.1.1.1 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A | 0.52 | 45.0 | 3.34e-01 | 93.2% | 47.6% |
| 5022905 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 48.0 | 3.88e-01 | 100.0% | 78.4% |
| 3388784 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.51 | 41.0 | 3.86e-01 | 87.4% | 96.0% |
D3
high
residues 298-385
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF25712.2 best | crAss_CARGO2 | 77.1 | 2.10e-21 | 100.0% | 16.0% |
CATH (7)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3i44A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.55 | 41.0 | 2.94e-01 | 80.7% | 83.9% |
| 4mdaA00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.54 | 46.0 | 3.59e-01 | 95.5% | 96.0% |
| 7uclA01 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.53 | 27.0 | 2.61e-01 | 94.3% | 40.2% |
| 3tgxB00 | 1.20.1250.70 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interleukin-15/Interleukin-21 | 0.52 | 46.0 | 4.23e-01 | 96.6% | 97.4% |
| 5ib9A01 | 3.40.630.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases | 0.52 | 38.0 | 2.80e-01 | 80.7% | 95.1% |
| 3cjlA00 | 3.10.20.850 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Protein of unknown function DUF3861 | 0.51 | 32.0 | 3.22e-01 | 96.6% | 61.4% |
| 2basB01 | 3.20.20.450 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › EAL domain | 0.50 | 33.0 | 2.52e-01 | 70.5% | 26.1% |
ECOD (16)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3605494 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.58 | 45.0 | 4.19e-01 | 92.0% | 64.3% |
| 3971223 | 7512.1.1.32 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_1_4 | 0.56 | 45.0 | 3.28e-01 | 89.8% | 90.7% |
| 3268288 | 5001.1.1.5 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 | 0.54 | 48.0 | 3.39e-01 | 100.0% | 81.4% |
| 4299747 | 3281.1.1.1 ↗ | alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related › Proton_antipo_M | 0.54 | 44.0 | 2.82e-01 | 94.3% | 80.0% |
| 4033381 | 3218.1.1.1 ↗ | a+b duplicates or obligate multimers › small terminase oligomerization domain › small terminase oligomerization domain › small terminase oligomerization domain › Terminase_2 | 0.54 | 36.0 | 3.86e-01 | 88.6% | 87.1% |
| 3276573 | 5001.1.1.5 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 | 0.52 | 46.0 | 3.34e-01 | 100.0% | 86.0% |
| None | — | 0.52 | 40.0 | 2.57e-01 | 89.8% | 52.0% | |
| 3678638 | 7579.1.1.14 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Lipase_3 | 0.52 | 43.0 | 2.86e-01 | 93.2% | 71.9% |
| 4946272 | 4018.1.1.2 ↗ | a+b two layers › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › Inositol_P | 0.51 | 43.0 | 3.61e-01 | 95.5% | 95.6% |
| 3695010 | 3435.1.1.3 ↗ | a+b two layers › Recombination-associated protein rdgC › Recombination-associated protein rdgC › Recombination-associated protein rdgC › CENP-L | 0.51 | 33.0 | 2.56e-01 | 86.4% | 26.1% |
| 3937690 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.51 | 44.0 | 3.07e-01 | 100.0% | 78.4% |
| 4009640 | 2002.5.1.1 ↗ | a/b barrels › TIM beta/alpha-barrel › EAL domain › EAL domain › EAL | 0.51 | 38.0 | 2.82e-01 | 83.0% | 28.8% |
| 3449956 | 7579.1.1.15 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Lipase_3,Lipase3_N | 0.50 | 41.0 | 2.83e-01 | 95.5% | 77.9% |
| 4028930 | 7581.1.1.1 ↗ | a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › Thiolase_N | 0.50 | 35.0 | 2.56e-01 | 83.0% | 23.6% |
| 3198044 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.50 | 42.0 | 4.09e-01 | 90.9% | 96.8% |
| 4298643 | 3281.1.1.2 ↗ | alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related › Proton_antipo_M,Proton_antipo_N | 0.50 | 41.0 | 2.63e-01 | 95.5% | 78.5% |
D4
high
residues 391-533
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF25712.2 best | crAss_CARGO2 | 137.0 | 1.50e-39 | 98.6% | 28.1% |
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3u8vA00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.59 | 34.0 | 4.47e-01 | 80.4% | 100.0% |
| 1rkiA01 | 3.30.70.1650 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › PDO, CxxC motif | 0.59 | 26.0 | 3.15e-01 | 87.4% | 59.8% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.55 | 38.0 | 4.44e-01 | 83.9% | 100.0% |
| 2pfmA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.53 | 46.0 | 3.79e-01 | 93.0% | 88.3% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4235474 | 4237.1.1.1 ↗ | beta barrels › FomD-like › FomD-like › FomD-like › DUF402 | 0.57 | 30.0 | 2.90e-01 | 88.1% | 42.1% |
| 3933098 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.53 | 25.0 | 3.55e-01 | 91.6% | 96.9% |
| 3415741 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.52 | 35.0 | 3.50e-01 | 94.4% | 66.2% |
| 5051010 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.51 | 32.0 | 3.62e-01 | 87.4% | 80.9% |
| 3479755 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.50 | 31.0 | 2.21e-01 | 95.1% | 17.9% |