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OQ330850.1__WDS38362.1__TMCBR4_gp053__00052

Bact-Vir

OQ330850.1__WDS38362.1__TMCBR4_gp053__00052

Identity

Accession:
OQ330850 ↗
Kingdom:
phage

Quality

83.3 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 8-63
PDB
Domain cluster: representative
CATH (62)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1vx7H01 3.90.930.12 Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › Ribosomal protein L6 0.81 65.0 5.64e-01 87.5% 100.0%
2o18A00 3.10.520.10 Alpha Beta › Roll › T-fold › ApbE-like domains 0.76 62.0 3.87e-01 92.9% 24.4%
2rqlA00 3.30.160.100 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Ribosome hibernation promotion factor-like 0.73 60.0 5.11e-01 92.9% 54.7%
4p1mB01 3.30.160.880 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Cell division protein ZapA protomer, N-terminal domain 0.71 51.0 5.49e-01 91.1% 97.8%
1imuA00 3.30.160.100 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Ribosome hibernation promotion factor-like 0.71 56.0 4.59e-01 94.6% 46.7%
1e3hA03 3.30.230.70 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › GHMP Kinase, N-terminal domain 0.69 49.0 3.32e-01 75.0% 50.7%
1dpbA00 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.69 50.0 3.28e-01 76.8% 31.3%
1mhxA00 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.67 48.0 4.62e-01 76.8% 67.7%
2qsrA01 3.90.1150.50 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Transcription-repair-coupling factor, D7 domain 0.67 51.0 3.68e-01 82.1% 97.4%
4ivkA00 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.67 53.0 3.18e-01 89.3% 37.9%
3maeA00 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.66 48.0 3.17e-01 76.8% 31.6%
2jl8102 3.30.160.850 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.66 40.0 4.26e-01 71.4% 73.3%
7r5mA01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.65 46.0 3.15e-01 76.8% 31.8%
1wchA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.65 54.0 3.44e-01 96.4% 75.6%
1c9fA00 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.65 50.0 4.36e-01 83.9% 85.1%
6zzmA01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.65 55.0 3.67e-01 94.6% 92.5%
3en9A03 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.65 49.0 4.56e-01 83.9% 72.6%
1ab8A00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.64 52.0 3.63e-01 87.5% 57.1%
2hj1A00 3.10.20.280 Alpha Beta › Roll › Ubiquitin-like (UB roll) › RnfH-like 0.63 45.0 4.10e-01 78.6% 55.8%
2bzlA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.62 51.0 3.32e-01 96.4% 86.3%
6l3tA01 1.20.1440.80 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Gap junction channel protein cysteine-rich domain 0.62 48.0 3.33e-01 85.7% 62.3%
2uvaG01 1.20.1050.120 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.62 50.0 3.84e-01 92.9% 83.8%
1txdA02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.61 46.0 3.57e-01 80.4% 37.2%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.61 42.0 3.13e-01 75.0% 25.1%
1qysA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.61 44.0 3.81e-01 80.4% 46.7%
2memA00 3.90.1150.190 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › SLED domain 0.61 47.0 3.70e-01 83.9% 45.4%
1zxhA00 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.61 41.0 4.17e-01 71.4% 73.2%
2q0oA01 3.30.450.80 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain 0.61 48.0 3.40e-01 85.7% 99.4%
3ulbA01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.60 45.0 3.96e-01 82.1% 54.2%
4mt4A00 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.60 50.0 3.00e-01 100.0% 91.3%
1neiA00 3.30.160.220 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › YoaG 0.60 45.0 4.50e-01 87.5% 90.0%
3nroA00 3.40.630.190 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › LCP protein 0.59 44.0 2.90e-01 78.6% 39.6%
3w3aG00 1.10.287.3240 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.59 50.0 3.43e-01 98.2% 40.0%
2jvfA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.59 40.0 3.48e-01 71.4% 45.7%
5b55A01 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.59 38.0 2.64e-01 83.9% 19.5%
4u7cB04 3.30.1490.100 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › DNA polymerase, Y-family, little finger domain 0.58 45.0 3.72e-01 87.5% 48.6%
3p9aF00 1.10.132.80 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.58 46.0 3.56e-01 89.3% 71.6%
3fehA02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.58 47.0 3.59e-01 87.5% 39.5%
2bb6A02 2.170.130.30 Mainly Beta › Beta Complex › Ferric Hydroxamate Uptake Protein; Chain A, domain 1 › 0.58 46.0 3.84e-01 91.1% 62.3%
2z8lA01 3.10.20.120 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.58 42.0 3.37e-01 78.6% 49.6%
2wxfA02 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.58 44.0 3.46e-01 82.1% 38.7%
1ti2B01 3.30.70.20 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 39.0 3.01e-01 71.4% 100.0%
6tmfI00 1.10.455.10 Mainly Alpha › Orthogonal Bundle › Ribosomal Protein S7 › Ribosomal protein S7/S5 0.57 47.0 3.17e-01 91.1% 59.3%
2eyqA07 3.90.1150.50 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Transcription-repair-coupling factor, D7 domain 0.57 42.0 3.21e-01 82.1% 45.6%
6cc0A01 3.30.450.80 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain 0.57 43.0 3.21e-01 87.5% 47.0%
1h0hB01 3.30.70.20 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 44.0 3.23e-01 85.7% 80.7%
2bwfA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.56 42.0 3.78e-01 80.4% 97.4%
1u8zA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 38.0 2.74e-01 73.2% 53.9%
2k3iA01 3.30.70.860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 37.0 3.30e-01 71.4% 76.5%
4ic1D00 3.90.320.10 Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › 0.55 46.0 3.23e-01 100.0% 52.9%
2dqlA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 40.0 3.16e-01 76.8% 75.7%
1yd0A00 3.40.1440.10 Alpha Beta › 3-Layer(aba) Sandwich › GIY-YIG endonuclease › GIY-YIG endonuclease 0.55 38.0 3.34e-01 75.0% 82.0%
1e7uA01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.54 38.0 2.76e-01 75.0% 50.3%
2fbiA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 42.0 3.21e-01 85.7% 60.3%
2ok5A02 2.40.10.120 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.54 39.0 2.64e-01 76.8% 34.2%
4mfzA02 3.40.630.120 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › 0.54 38.0 2.89e-01 76.8% 32.7%
2khdA00 3.30.70.860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 37.0 3.08e-01 73.2% 57.4%
5dymA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 41.0 3.43e-01 82.1% 89.6%
2xzmG00 1.10.455.10 Mainly Alpha › Orthogonal Bundle › Ribosomal Protein S7 › Ribosomal protein S7/S5 0.53 42.0 2.87e-01 85.7% 55.2%
4ca1B02 2.60.210.10 Mainly Beta › Sandwich › Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A › Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 0.53 46.0 3.50e-01 98.2% 84.1%
2p92A00 3.30.70.1490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp 0.53 43.0 3.63e-01 89.3% 83.2%
3cm1A00 2.30.31.20 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Sporulation-specific cell division protein SsgB 0.51 38.0 2.95e-01 82.1% 71.3%
ECOD (67)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4467663 601.51.1.2 alpha bundles › Four-helical up-and-down bundle › alpha-helical domain in phase 1 flagellin › alpha-helical domain in phase 1 flagellin › Flagellin_N,Flagellin_C 0.79 46.0 2.89e-01 100.0% 11.8%
5003062 230.4.1.1 a+b two layers › T-fold › ApbE-like › ApbE-like › ApbE 0.78 68.0 4.81e-01 98.2% 77.5%
3216210 3115.1.1.0 a+b two layers › GP2-like › RplX-like › RplX-like 0.77 53.0 5.55e-01 71.4% 80.0%
3466238 206.1.1.14 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1 0.76 47.0 2.71e-01 96.4% 7.8%
1944087 330.2.1.1 a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) › Ribosomal_S30AE 0.76 65.0 5.13e-01 96.4% 52.6%
4528517 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.75 55.0 5.98e-01 80.4% 100.0%
4599652 304.162.1.1 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH 0.74 54.0 4.77e-01 76.8% 90.0%
4492101 318.1.1.1 a+b two layers › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal_L6 0.73 53.0 4.57e-01 78.6% 95.6%
4518508 4271.1.1.3 alpha complex topology › PriB N-terminal domain-like › PriB N-terminal domain-like › PriB N-terminal domain-like › DNA_primase_lrg_N 0.73 53.0 3.54e-01 76.8% 61.4%
3684015 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.73 50.0 4.05e-01 71.4% 59.0%
4183868 878.1.1.1 a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 0.73 57.0 5.06e-01 83.9% 63.3%
3988478 857.1.1.1 a+b duplicates or obligate multimers › Cell division protein ZapA-like › Cell division protein ZapA-like › Cell division protein ZapA-like › ZapA 0.73 54.0 4.52e-01 89.3% 45.9%
4679312 304.162.1.1 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH 0.72 52.0 4.64e-01 76.8% 91.3%
4220559 304.162.1.1 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH 0.72 55.0 4.87e-01 82.1% 93.8%
4961640 5001.1.1.292 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HisKA_7TM 0.71 51.0 3.30e-01 75.0% 85.4%
3173493 323.1.1.1 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › 2-oxoacid_dh 0.71 51.0 3.36e-01 76.8% 31.8%
4985406 878.1.1.1 a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 0.69 54.0 4.82e-01 83.9% 64.6%
3711985 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.68 55.0 3.58e-01 89.3% 46.4%
5073431 1075.1.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.68 55.0 3.17e-01 89.3% 37.3%
4988512 101.1.2.14 alpha arrays › HTH › HTH › winged helix domain › HTH_5 0.67 48.0 3.31e-01 75.0% 41.0%
4268395 857.1.1.1 a+b duplicates or obligate multimers › Cell division protein ZapA-like › Cell division protein ZapA-like › Cell division protein ZapA-like › ZapA 0.66 55.0 4.73e-01 98.2% 57.3%
4091699 857.1.1.1 a+b duplicates or obligate multimers › Cell division protein ZapA-like › Cell division protein ZapA-like › Cell division protein ZapA-like › ZapA 0.66 53.0 4.51e-01 98.2% 52.0%
4564327 878.1.1.1 a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 0.65 47.0 4.19e-01 78.6% 54.2%
3623124 3346.1.1.1 a+b two layers › N-terminal domain in ubiquitin-fold modifier 1 specific protease UfSP2 › N-terminal domain in ubiquitin-fold modifier 1 specific protease UfSP2 › N-terminal domain in ubiquitin-fold modifier 1 specific protease UfSP2 › UfSP2_N 0.64 55.0 3.71e-01 96.4% 62.7%
68010 306.8.1.1 a+b two layers › Glucose permease domain IIB-like › TM1457-like › TM1457-like › Peptidase_Prp 0.64 44.0 3.68e-01 71.4% 92.8%
5010744 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.63 44.0 4.21e-01 73.2% 90.8%
3679515 3115.1.1.1 a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A 0.63 44.0 4.74e-01 76.8% 97.8%
5068716 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.62 48.0 3.00e-01 83.9% 57.5%
5072662 2485.1.1.0 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like 0.62 46.0 3.56e-01 82.1% 71.1%
5043498 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.62 48.0 2.90e-01 85.7% 46.7%
3208120 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.62 50.0 3.65e-01 89.3% 78.7%
4585964 167.1.1.1 alpha arrays › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal_S7 0.62 47.0 3.36e-01 87.5% 75.3%
5005387 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.62 49.0 3.24e-01 87.5% 64.1%
4957785 7523.1.1.0 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II 0.62 46.0 3.74e-01 82.1% 45.5%
5074130 1075.1.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.62 53.0 3.41e-01 96.4% 42.4%
4437052 167.1.1.1 alpha arrays › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal_S7 0.61 47.0 3.59e-01 89.3% 72.0%
3798829 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.61 49.0 3.24e-01 87.5% 74.2%
3958077 244.1.1.0 a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C 0.61 48.0 3.50e-01 89.3% 90.3%
3740226 5051.1.1.7 alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Nramp 0.61 52.0 3.04e-01 96.4% 59.6%
2755642 167.1.1.1 alpha arrays › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal_S7 0.60 47.0 3.18e-01 85.7% 24.0%
3996281 110.3.1.1 alpha arrays › DEATH domain › SLED domain › SLED domain › SLED 0.60 44.0 3.57e-01 78.6% 40.0%
4505972 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.60 49.0 3.06e-01 91.1% 22.2%
3625339 304.126.1.0 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C 0.60 45.0 3.85e-01 83.9% 74.7%
5058268 101.1.2.54 alpha arrays › HTH › HTH › winged helix domain › Penicillinase_R 0.59 45.0 3.54e-01 82.1% 88.7%
3739985 101.1.2.98 alpha arrays › HTH › HTH › winged helix domain › CDT1 0.59 45.0 3.23e-01 82.1% 60.6%
3482807 277.1.1.0 a+b two layers › PX domain › PX domain › PX domain 0.59 48.0 3.88e-01 89.3% 81.5%
4995222 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.59 40.0 3.68e-01 71.4% 92.0%
4026685 150.1.1.51 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › PqiA 0.59 49.0 3.23e-01 94.6% 76.4%
3472537 219.1.1.3 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.59 48.0 2.98e-01 98.2% 35.2%
3653902 2484.1.1.1 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 0.58 41.0 2.78e-01 75.0% 54.9%
3794803 221.1.1.153 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › Ubiquitin_PRKD1_N 0.58 44.0 3.94e-01 98.2% 54.7%
3292295 221.1.1.4 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › PB1 0.57 38.0 3.30e-01 73.2% 41.1%
3739303 302.1.1.1 a+b two layers › Reverse ferredoxin › Lesion bypass DNA polymerase (Y-family), little finger domain › Lesion bypass DNA polymerase (Y-family), little finger domain › IMS_C 0.57 43.0 3.54e-01 87.5% 47.5%
4959664 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.57 42.0 2.82e-01 80.4% 33.6%
3723914 327.11.2.40 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › PF31052 0.55 40.0 3.85e-01 78.6% 100.0%
3317524 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.55 44.0 2.90e-01 96.4% 22.0%
4076218 1.1.7.15 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Peptidase_M18 0.55 39.0 3.10e-01 76.8% 70.4%
3575090 11.1.1.97 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › I-set 0.54 46.0 3.14e-01 94.6% 27.7%
3459413 5.1.4.39 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › ANAPC4_WD40 0.54 42.0 2.57e-01 89.3% 14.5%
3273867 221.1.1.4 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › PB1 0.53 40.0 3.52e-01 82.1% 92.9%
3363670 221.1.1.4 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › PB1 0.53 39.0 3.20e-01 80.4% 73.6%
4153047 167.1.1.1 alpha arrays › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal_S7 0.53 43.0 3.16e-01 89.3% 78.7%
4026560 2485.1.1.0 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like 0.53 38.0 3.26e-01 80.4% 81.0%
3222177 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.53 37.0 3.25e-01 80.4% 46.2%
3887061 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.53 37.0 3.37e-01 80.4% 51.8%
3939958 11.1.1.97 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › I-set 0.51 40.0 3.18e-01 91.1% 52.3%
3576255 7502.1.1.0 a/b three-layered sandwiches › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS 0.50 36.0 2.88e-01 76.8% 85.2%
D2 medium residues 64-159
PDB
Domain cluster: representative
CATH (34)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1qdbA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.78 48.0 4.16e-01 95.8% 42.0%
5i1uA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.73 56.0 3.88e-01 99.0% 26.0%
6vydA01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.72 56.0 3.89e-01 93.8% 26.5%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.70 50.0 5.56e-01 92.7% 92.2%
5nx5B00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.68 55.0 3.82e-01 99.0% 28.1%
4mc3A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.65 46.0 3.27e-01 97.9% 24.4%
8d7fC01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.64 54.0 3.72e-01 95.8% 27.6%
7kypB01 1.10.3470.10 Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC 0.64 49.0 3.60e-01 83.3% 83.4%
6p73A02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.63 41.0 3.56e-01 84.4% 44.8%
3v5uA01 6.10.280.80 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region 0.62 47.0 5.18e-01 100.0% 100.0%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.62 49.0 4.78e-01 94.8% 75.7%
1w07A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.60 48.0 3.93e-01 97.9% 48.2%
2q7rB00 1.20.120.550 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain 0.59 40.0 3.51e-01 91.7% 45.6%
1gvnA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.59 32.0 3.38e-01 85.4% 56.3%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.59 51.0 4.49e-01 96.9% 65.2%
6mh4A03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.59 29.0 3.15e-01 80.2% 55.7%
1gs0A01 1.20.142.10 Mainly Alpha › Up-down Bundle › Poly(ADP-ribose) Polymerase; domain 1 › Poly(ADP-ribose) polymerase, regulatory domain 0.58 51.0 4.65e-01 97.9% 82.9%
4mycA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.58 50.0 3.38e-01 96.9% 27.1%
3unoE00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.57 50.0 4.17e-01 96.9% 65.9%
1lkoA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.57 46.0 4.04e-01 88.5% 73.8%
3o7qA02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.56 51.0 4.03e-01 99.0% 92.7%
3h3mA00 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.56 40.0 4.20e-01 99.0% 79.8%
1r0dA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.56 52.0 4.07e-01 100.0% 75.1%
1nu7D01 1.20.120.750 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Staphylcoagulase, helix bundle domain 1 0.56 39.0 3.47e-01 70.8% 91.1%
2nwlC00 1.10.3860.10 Mainly Alpha › Orthogonal Bundle › Proton glutamate symport protein › Sodium:dicarboxylate symporter 0.55 42.0 2.85e-01 83.3% 67.2%
1e6dM01 1.20.85.10 Mainly Alpha › Up-down Bundle › Photosynthetic Reaction Center, subunit M; domain 1 › Photosystem II protein D1-like 0.55 47.0 4.11e-01 97.9% 62.2%
7e84A03 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.55 49.0 4.48e-01 96.9% 78.9%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.55 48.0 4.46e-01 94.8% 96.7%
1htjF00 1.10.167.10 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 0.53 43.0 3.58e-01 90.6% 53.8%
2yevB01 1.10.287.90 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.53 40.0 4.11e-01 94.8% 81.7%
1f1mA00 1.20.120.240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 0.52 44.0 3.81e-01 96.9% 84.6%
2wjnM01 1.20.85.10 Mainly Alpha › Up-down Bundle › Photosynthetic Reaction Center, subunit M; domain 1 › Photosystem II protein D1-like 0.52 45.0 3.91e-01 94.8% 62.9%
4h33A00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.51 44.0 4.52e-01 97.9% 100.0%
1hbgA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 38.0 3.33e-01 90.6% 51.7%
ECOD (44)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5012473 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.80 59.0 5.61e-01 97.9% 66.4%
5005708 3755.3.1.127 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › NFACT_N 0.71 66.0 5.21e-01 97.9% 54.4%
3270487 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.70 57.0 5.41e-01 100.0% 74.5%
4049927 4044.1.1.1 alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Prismane 0.70 42.0 4.22e-01 96.9% 60.0%
5041715 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.68 62.0 5.93e-01 97.9% 86.4%
3582505 611.8.1.8 alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › UBR4 0.65 58.0 5.33e-01 100.0% 75.2%
3695989 5063.1.1.14 alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › MARCHF6_C 0.64 51.0 3.98e-01 83.3% 86.2%
3189960 141.1.1.8 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › Terpene_syn_C_2 0.64 57.0 3.87e-01 97.9% 27.8%
3428908 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 42.0 2.58e-01 99.0% 10.7%
4561800 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.64 39.0 3.47e-01 82.3% 44.6%
3279024 150.5.1.51 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100_2 0.63 58.0 5.14e-01 96.9% 73.8%
3916954 621.1.1.0 alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain 0.63 53.0 4.71e-01 95.8% 85.5%
3567390 150.3.1.30 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › IL31 0.62 52.0 4.76e-01 89.6% 100.0%
3225754 632.6.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit 0.62 45.0 4.53e-01 74.0% 85.3%
5071167 606.1.1.1 alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Nop 0.62 49.0 4.42e-01 89.6% 60.7%
3616872 3718.1.1.17 alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT › PF29069 0.61 44.0 4.19e-01 74.0% 94.5%
3961947 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.61 55.0 4.60e-01 100.0% 59.4%
4286866 620.1.1.6 alpha bundles › YfiT-like putative metal-dependent hydrolases › YfiT-like putative metal-dependent hydrolases › YfiT-like putative metal-dependent hydrolases › DinB_2 0.61 53.0 4.36e-01 96.9% 98.3%
4487150 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.61 55.0 3.69e-01 97.9% 27.8%
None 0.61 52.0 4.33e-01 95.8% 98.3%
4471275 5065.1.1.2 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › FecCD 0.61 49.0 3.50e-01 88.5% 80.9%
3267613 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.60 54.0 4.05e-01 100.0% 64.7%
4851440 609.1.1.1 alpha bundles › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase › PARP_reg 0.59 53.0 4.64e-01 100.0% 72.8%
3747865 5050.1.1.6 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › OATP 0.59 52.0 3.70e-01 96.9% 78.3%
3253767 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.59 55.0 4.61e-01 100.0% 65.2%
4033757 5065.1.1.2 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › FecCD 0.59 49.0 3.46e-01 90.6% 80.6%
3897765 5059.1.1.0 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter 0.59 48.0 4.28e-01 97.9% 61.4%
3975328 3718.1.1.1 alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT › FliT 0.58 40.0 4.20e-01 96.9% 80.0%
4887997 5037.1.1.1 alpha bundles › Bacterial photosystem II reaction centre L and M subunits-like › Bacterial photosystem II reaction centre L and M subunits-like › Bacterial photosystem II reaction centre L and M subunits-like › Photo_RC 0.57 51.0 3.49e-01 97.9% 28.7%
3874338 150.3.1.22 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › PRF 0.57 50.0 4.11e-01 100.0% 95.1%
3400356 620.1.1.0 alpha bundles › YfiT-like putative metal-dependent hydrolases › YfiT-like putative metal-dependent hydrolases › YfiT-like putative metal-dependent hydrolases 0.56 47.0 4.04e-01 94.8% 78.1%
3961790 150.8.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE › PPE 0.56 48.0 4.37e-01 100.0% 70.0%
3799166 5001.1.1.3 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 0.56 47.0 3.40e-01 96.9% 79.7%
3800622 5001.1.1.3 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 0.55 47.0 3.39e-01 96.9% 79.7%
4015527 7022.1.1.0 alpha bundles › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein 0.55 46.0 4.18e-01 99.0% 68.8%
3171096 5054.1.1.12 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › NCA2 0.54 50.0 4.10e-01 100.0% 61.8%
3927014 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.54 48.0 4.19e-01 100.0% 87.3%
4959289 606.1.1.0 alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain 0.54 44.0 4.51e-01 99.0% 89.5%
3508094 2003.1.2.24 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Pyr_redox_2 0.54 46.0 3.07e-01 96.9% 95.2%
5054405 606.1.1.1 alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Nop 0.53 49.0 4.84e-01 100.0% 99.0%
3918686 109.2.1.46 alpha superhelices › Repetitive alpha hairpins › alpha/alpha toroid › alpha/alpha toroid › DUF4735 0.53 47.0 3.28e-01 95.8% 100.0%
3216082 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.52 38.0 3.56e-01 75.0% 87.8%
3763126 150.3.1.30 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › IL31 0.52 42.0 3.82e-01 95.8% 65.4%
4979715 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.52 40.0 3.43e-01 97.9% 52.7%