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OQ401624.1__WED25129.1__CRP902_gp33__00033

Bact-Vir

OQ401624.1__WED25129.1__CRP902_gp33__00033

Identity

Accession:
OQ401624 ↗
Kingdom:
phage

Quality

76.9 mean pLDDT

Taxonomy

Heunggongvirae› Uroviricota› Caudoviricetes› Roseobacter_phage_CRP-902

TaxID: 3032257

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 24-119
PDB
Domain cluster: representative
CATH (40)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2g8lB01 1.10.8.380 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 0.70 37.0 4.35e-01 97.9% 73.1%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.70 55.0 5.09e-01 83.3% 67.5%
4hwhE00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.69 39.0 4.07e-01 83.3% 60.2%
4hwdD00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.69 38.0 4.01e-01 83.3% 58.9%
3s84A02 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.67 55.0 4.71e-01 89.6% 56.7%
2oauA01 1.10.287.1260 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 45.0 4.42e-01 89.6% 63.7%
7odyC01 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.66 32.0 3.27e-01 74.0% 47.8%
8ex5A02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.66 49.0 3.78e-01 79.2% 95.9%
3n98A02 1.20.1430.10 Mainly Alpha › Up-down Bundle › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase, middle domain 0.65 41.0 3.65e-01 77.1% 44.8%
2wb7A03 1.20.120.870 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain 0.64 43.0 3.81e-01 78.1% 47.8%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.64 51.0 5.46e-01 86.5% 100.0%
4qndA00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.64 35.0 3.55e-01 78.1% 53.6%
3qweA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.63 54.0 3.95e-01 93.8% 76.9%
2nr9A00 1.20.1540.10 Mainly Alpha › Up-down Bundle › Rhomboid-like fold › Rhomboid-like 0.63 41.0 3.23e-01 78.1% 33.3%
3u3iA02 1.20.58.1110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 42.0 4.09e-01 78.1% 61.1%
1ek9A00 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.62 50.0 3.27e-01 86.5% 30.6%
3r84B00 6.10.280.160 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 0.62 47.0 5.07e-01 79.2% 100.0%
4nooB00 1.10.8.1160 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.62 42.0 4.29e-01 99.0% 70.5%
3a06B03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.62 39.0 4.04e-01 100.0% 68.2%
2v0oB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.62 48.0 3.47e-01 83.3% 29.5%
1w0bA01 1.20.58.420 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP 0.59 38.0 3.95e-01 86.5% 68.5%
3vz3A01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.58 41.0 3.05e-01 74.0% 85.2%
4bwzA00 1.20.1530.20 Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › 0.58 43.0 2.92e-01 81.2% 64.8%
3vbbE01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.57 46.0 4.28e-01 86.5% 100.0%
3nymA00 6.10.290.10 Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.57 43.0 3.95e-01 79.2% 91.1%
3l4aA00 1.10.238.20 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain 0.57 32.0 2.98e-01 96.9% 42.1%
3lphC00 6.10.140.630 Special › Helix non-globular › Helix Hairpins › 0.57 35.0 4.09e-01 81.2% 100.0%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.57 44.0 4.61e-01 83.3% 93.3%
2zxqA06 1.20.1270.70 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle 0.56 32.0 3.72e-01 100.0% 81.8%
2g8lA02 1.10.285.20 Mainly Alpha › Orthogonal Bundle › Glutamate Dehydrogenase; Chain A, domain 3 › Uncharacterised protein PF01937, DUF89, domain 2 0.55 28.0 3.30e-01 100.0% 69.2%
2q12A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.55 44.0 3.32e-01 87.5% 66.9%
6iknD01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.54 47.0 3.51e-01 100.0% 79.0%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.54 46.0 3.78e-01 95.8% 96.2%
7lb8B01 1.10.3470.10 Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC 0.54 46.0 3.31e-01 99.0% 88.6%
2y1vA04 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 34.0 2.81e-01 94.8% 33.0%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.54 43.0 4.29e-01 89.6% 84.3%
1h6gA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.53 42.0 3.86e-01 83.3% 100.0%
4j05A00 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.52 43.0 2.80e-01 88.5% 81.5%
7e84A03 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.52 38.0 3.59e-01 80.2% 90.2%
3cexA00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.51 46.0 3.78e-01 99.0% 90.0%
ECOD (51)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3506685 1134.1.1.0 ↗ alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain 0.71 36.0 4.03e-01 76.0% 62.7%
3496238 5082.1.1.0 ↗ alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like 0.71 53.0 4.01e-01 82.3% 34.9%
3362816 4177.2.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain 0.69 51.0 3.57e-01 87.5% 25.4%
3598977 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.69 53.0 5.57e-01 89.6% 92.9%
4026795 3871.1.1.1 ↗ alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.67 56.0 4.96e-01 100.0% 62.9%
3731997 3831.1.1.0 ↗ alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 0.66 49.0 4.47e-01 77.1% 77.6%
4101843 632.7.1.1 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 0.65 41.0 3.96e-01 87.5% 57.1%
None — 0.65 55.0 3.95e-01 91.7% 61.7%
4129365 5050.1.1.56 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr, TRI12 0.65 53.0 3.26e-01 87.5% 44.3%
3985973 3755.4.1.84 ↗ alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › DUF1202 0.65 52.0 4.38e-01 87.5% 51.5%
3962159 1075.5.1.2 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ 0.64 48.0 4.07e-01 79.2% 47.5%
3489761 4177.1.1.2 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.64 53.0 4.04e-01 90.6% 73.8%
4267909 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.64 54.0 4.25e-01 91.7% 83.1%
4979114 150.1.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.63 47.0 4.28e-01 78.1% 60.8%
3672993 150.5.1.6 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › DUF3082 0.62 44.0 4.17e-01 91.7% 60.9%
3420431 632.7.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.62 36.0 3.80e-01 85.4% 63.5%
3921009 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.62 47.0 3.10e-01 82.3% 28.2%
4988301 3877.1.1.0 ↗ alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC 0.60 50.0 4.35e-01 91.7% 61.3%
3208614 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.60 43.0 3.96e-01 75.0% 60.8%
3421052 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.60 53.0 3.96e-01 96.9% 45.1%
4940075 632.11.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.59 37.0 4.01e-01 100.0% 75.0%
5017845 632.7.1.67 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › YetF_N 0.59 38.0 4.06e-01 100.0% 74.1%
3923614 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.59 53.0 4.40e-01 96.9% 91.3%
3739490 3939.1.1.374 ↗ alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › PF30554 0.58 47.0 3.46e-01 86.5% 93.5%
3836427 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.58 45.0 4.46e-01 83.3% 84.0%
4131078 632.7.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.58 35.0 3.81e-01 97.9% 72.5%
4930709 3877.1.1.0 ↗ alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC 0.58 47.0 3.77e-01 91.7% 44.1%
4139865 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.57 43.0 3.17e-01 90.6% 30.5%
4032991 6072.1.1.0 ↗ alpha arrays › Transmembrane domain of envelope protein E › Transmembrane domain of envelope protein E › Transmembrane domain of envelope protein E 0.57 36.0 3.63e-01 96.9% 63.2%
3491709 192.7.1.2 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.57 47.0 4.08e-01 89.6% 95.2%
3422909 2003.1.2.15 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_3 0.56 41.0 3.13e-01 77.1% 45.3%
5036723 4323.1.1.0 ↗ alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C 0.56 50.0 4.20e-01 100.0% 72.7%
4943642 3291.1.1.0 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.56 44.0 4.07e-01 83.3% 67.5%
3282601 150.8.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE 0.56 50.0 3.99e-01 100.0% 66.2%
3237980 2003.1.2.18 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.56 42.0 2.55e-01 79.2% 13.6%
3330173 5050.1.1.58 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › NFD4_C 0.55 39.0 3.38e-01 75.0% 71.0%
3224363 3831.1.1.0 ↗ alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 0.55 37.0 3.93e-01 96.9% 80.0%
3490411 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.55 38.0 3.05e-01 72.9% 63.9%
4022306 3939.1.1.0 ↗ alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain 0.54 45.0 3.91e-01 90.6% 79.3%
3235302 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.54 45.0 3.36e-01 91.7% 81.2%
3631949 309.1.2.5 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › ThrRS/AlaRS editing domain › Seryl_tRNA_N 0.54 47.0 4.36e-01 97.9% 96.8%
4431938 507.1.1.7 ↗ alpha arrays › DnaB helicase N-terminal domain-related › DnaB helicase N-terminal domain-related › DnaB helicase N-terminal domain-related › PF30523 0.54 42.0 3.37e-01 86.5% 82.9%
5077964 3355.1.1.41 ↗ alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DUF401 0.53 45.0 3.15e-01 97.9% 64.1%
5006400 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.53 44.0 3.36e-01 90.6% 56.5%
3215342 3291.1.1.0 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.53 44.0 4.47e-01 92.7% 92.6%
4954644 192.7.1.0 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.53 37.0 3.52e-01 76.0% 59.2%
5045811 4323.1.1.0 ↗ alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C 0.53 46.0 3.91e-01 99.0% 75.8%
3519620 190.1.1.0 ↗ alpha arrays › HMG-box-like › HMG-box › HMG-box 0.52 40.0 3.86e-01 82.3% 75.5%
4175967 3291.1.1.0 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.51 38.0 4.01e-01 78.1% 90.6%
3696407 4121.1.1.7 ↗ a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › PF26616 0.51 44.0 3.43e-01 100.0% 48.9%
3703542 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.50 40.0 3.63e-01 89.6% 62.9%
D2 high residues 375-522
PDB
Domain cluster: rep: MG592643.1__AUS00456.1__NVP1275O_16__00016__D215-390
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4l8jA04 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.74 29.0 4.53e-01 81.8% 89.8%
3kyiA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.67 46.0 5.00e-01 80.4% 82.0%
2mtqA00 1.20.58.130 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 30.0 4.11e-01 95.3% 83.6%
1vf7A03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.66 29.0 4.38e-01 82.4% 100.0%
1ihgA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.63 30.0 3.10e-01 100.0% 45.5%
4nv0A02 1.10.150.340 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Pyrimidine 5'-nucleotidase (UMPH-1), N-terminal domain 0.62 26.0 3.44e-01 85.8% 68.3%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.62 32.0 3.80e-01 77.7% 71.0%
3pwxA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.60 47.0 4.35e-01 83.1% 65.2%
2hsbA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.57 45.0 4.82e-01 81.8% 97.6%
6xkyA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.57 45.0 4.17e-01 83.1% 75.9%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.57 45.0 4.84e-01 84.5% 97.7%
1i36A02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.56 37.0 4.40e-01 98.6% 100.0%
2d2sA02 1.20.58.1220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain 0.55 33.0 3.93e-01 100.0% 87.1%
1io1A01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.55 44.0 4.26e-01 84.5% 87.6%
3v5uA01 6.10.280.80 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region 0.55 28.0 3.81e-01 77.0% 96.1%
2dnxA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 35.0 3.72e-01 93.2% 73.8%
1s35A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 33.0 3.90e-01 100.0% 89.1%
1cnt200 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.54 43.0 4.60e-01 84.5% 100.0%
4od4A01 1.10.357.140 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › UbiA prenyltransferase 0.54 41.0 4.04e-01 79.7% 76.3%
4ie5A02 1.20.58.1470 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FTO C-terminal domain 0.53 34.0 3.59e-01 100.0% 70.1%
1oxjA02 1.25.40.170 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Smaug, PHAT domain 0.53 33.0 3.81e-01 96.6% 83.5%
4o6yB00 1.20.120.1770 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.53 49.0 4.36e-01 100.0% 81.0%
1pu6A01 1.10.1670.10 Mainly Alpha › Orthogonal Bundle › Endonuclease Iii, domain 2 › Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 0.52 28.0 3.40e-01 89.2% 79.8%
2gscC00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.52 33.0 3.73e-01 70.3% 83.6%
4od4A02 1.20.120.1780 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase 0.51 38.0 4.22e-01 81.1% 95.8%
3vhlA02 1.20.58.740 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DOCK DHR2 domain, lobe C 0.51 33.0 3.57e-01 99.3% 77.5%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.51 34.0 3.81e-01 99.3% 86.2%
ECOD (21)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4986986 3633.1.1.0 ↗ alpha duplicates or obligate multimers › Haptoglobin-hemoglobin receptor › Haptoglobin-hemoglobin receptor › Haptoglobin-hemoglobin receptor 0.74 32.0 2.85e-01 83.1% 30.2%
3995513 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.66 34.0 3.47e-01 83.8% 49.7%
4299710 174.1.1.1 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.65 38.0 3.55e-01 100.0% 47.2%
3740106 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.64 38.0 4.28e-01 100.0% 75.7%
3684945 601.1.2.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.62 32.0 3.37e-01 79.7% 53.6%
4371183 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.60 36.0 3.62e-01 99.3% 58.0%
4512919 192.29.1.4 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Opi1 0.58 46.0 4.30e-01 82.4% 91.1%
4542751 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.58 35.0 3.44e-01 99.3% 55.0%
3801950 3755.4.1.0 ↗ alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.57 42.0 3.73e-01 82.4% 53.7%
3636791 192.29.1.4 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Opi1 0.57 45.0 4.24e-01 82.4% 92.0%
3395652 601.1.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.56 41.0 4.60e-01 83.1% 98.3%
5032124 4031.1.1.0 ↗ a+b three layers › Nigritoxin middle domain › Nigritoxin middle domain › Nigritoxin middle domain 0.55 45.0 4.08e-01 86.5% 69.0%
3974731 601.52.1.2 ↗ alpha bundles › Four-helical up-and-down bundle › Flagellar hook-associated protein 1 helical domain › Flagellar hook-associated protein 1 helical domain › FlgK_D1 0.55 44.0 3.33e-01 83.1% 94.4%
5061899 1079.1.1.1 ↗ alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD 0.54 39.0 3.44e-01 75.0% 92.9%
3213281 4177.1.1.1 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.53 30.0 2.42e-01 84.5% 30.4%
3504894 101.1.9.76 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › Membralin 0.52 37.0 3.27e-01 100.0% 49.8%
5000186 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 41.0 3.57e-01 83.1% 89.8%
3312807 3922.1.1.7 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Auxin_canalis 0.52 38.0 3.83e-01 83.1% 76.6%
3436831 601.4.1.52 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › Auxin_canalis 0.52 39.0 4.12e-01 85.1% 89.2%
3671851 5086.1.1.47 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Auxin_canalis 0.51 38.0 3.98e-01 85.1% 83.7%
3484616 109.42.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › E3 ubiquitin-protein ligase SHPRH first helical domain › E3 ubiquitin-protein ligase SHPRH first helical domain › SHPRH_helical-1st 0.50 32.0 3.23e-01 99.3% 64.1%
D3 high residues 531-585
PDB
Domain cluster: representative
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2e52B01 3.40.91.70 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › Type II restriction endonuclease, HindIII 0.77 68.0 4.45e-01 98.2% 28.1%
3q5dA02 1.20.58.420 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP 0.70 62.0 5.16e-01 100.0% 86.6%
2jqtA00 1.20.1280.40 Mainly Alpha › Up-down Bundle › Monooxygenase › HHA 0.68 52.0 5.17e-01 89.1% 82.5%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.66 43.0 3.51e-01 76.4% 37.4%
8gpvA01 1.25.60.10 Mainly Alpha › Alpha Horseshoe › MgtE N-terminal fold › MgtE N-terminal domain-like 0.64 50.0 3.80e-01 85.5% 36.4%
2wy4A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.62 52.0 4.02e-01 100.0% 97.1%
3fbiD00 1.10.10.1340 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Mediator of RNA polymerase II, submodule Med31 (Soh1) 0.61 45.0 4.00e-01 87.3% 72.3%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.60 51.0 4.17e-01 98.2% 87.9%
2kjgA00 1.20.120.970 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.59 49.0 4.12e-01 96.4% 59.6%
2lw1A00 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.58 42.0 3.65e-01 76.4% 49.4%
2ffjA02 1.10.285.20 Mainly Alpha › Orthogonal Bundle › Glutamate Dehydrogenase; Chain A, domain 3 › Uncharacterised protein PF01937, DUF89, domain 2 0.58 39.0 3.76e-01 70.9% 64.6%
2ycdA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 47.0 3.81e-01 96.4% 72.6%
3lxuX06 1.25.40.710 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.57 48.0 3.18e-01 100.0% 36.9%
1hwyA01 1.10.287.140 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.56 40.0 4.16e-01 76.4% 88.2%
4h63K00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.54 38.0 3.22e-01 76.4% 42.9%
4ymuD00 1.10.3720.10 Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like 0.52 42.0 2.93e-01 96.4% 51.2%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3673226 622.2.1.0 ↗ alpha bundles › YvfG-like › YvfG-like › YvfG-like 0.84 75.0 7.50e-01 94.5% 98.2%
4030400 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.78 68.0 3.89e-01 100.0% 9.8%
3877694 145.1.1.3 ↗ alpha arrays › F-box domain › F-box domain › F-box domain › F-box-like 0.72 54.0 5.33e-01 90.9% 75.0%
4195318 145.1.1.1 ↗ alpha arrays › F-box domain › F-box domain › F-box domain › F-box 0.72 54.0 5.00e-01 90.9% 64.3%
3540940 109.4.1.434 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FAST_1 0.70 60.0 3.60e-01 100.0% 13.6%
3881666 145.1.1.1 ↗ alpha arrays › F-box domain › F-box domain › F-box domain › F-box 0.70 52.0 4.87e-01 90.9% 64.3%
3496953 4030.1.1.0 ↗ alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz 0.68 53.0 5.18e-01 85.5% 76.7%
3781066 101.1.17.0 ↗ alpha arrays › HTH › HTH › FF domain 0.67 53.0 5.37e-01 87.3% 100.0%
4962041 304.55.1.0 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains 0.66 54.0 3.74e-01 94.5% 26.5%
3534690 4030.1.1.2 ↗ alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › F-actin_cap_A 0.64 51.0 5.19e-01 94.5% 94.5%
4678690 4048.1.1.0 ↗ alpha bundles › Second alpha-helical domain in heme-dependent catalases › Second alpha-helical domain in heme-dependent catalases › Second alpha-helical domain in heme-dependent catalases 0.63 54.0 4.84e-01 100.0% 70.0%
3805367 185.1.1.2 ↗ alpha superhelices › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin-like › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin/Protein HNS-dependent expression A HdeA › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin › LTP_2 0.63 48.0 4.53e-01 85.5% 74.3%
3253588 130.1.1.0 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif 0.63 42.0 4.13e-01 87.3% 63.3%
3601480 7022.1.1.0 ↗ alpha bundles › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein 0.61 49.0 3.00e-01 100.0% 15.5%
3598653 130.1.1.0 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif 0.61 38.0 4.14e-01 85.5% 75.6%
3198528 130.1.1.16 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › Ish1 0.61 48.0 4.84e-01 87.3% 85.5%
3270160 603.1.1.3 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.59 52.0 4.28e-01 100.0% 81.0%
4145351 3455.1.1.0 ↗ alpha arrays › WY-domain in RXLR effectors › WY-domain in RXLR effectors › WY-domain in RXLR effectors 0.57 50.0 4.80e-01 100.0% 98.4%
3447846 5010.1.1.6 ↗ extended segments › Bacterial aa3 type cytochrome c oxidase subunit IV › Bacterial aa3 type cytochrome c oxidase subunit IV › Bacterial aa3 type cytochrome c oxidase subunit IV › SPC12 0.55 41.0 4.34e-01 78.2% 100.0%
D4 medium residues 164-211
PDB
Domain cluster: representative
CATH (29)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3k59A02 3.30.70.2250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › B family DNA polymerase, N domain, alpha/beta motif 0.74 64.0 5.80e-01 100.0% 97.0%
3tj8A02 3.30.70.790 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › UreE, C-terminal domain 0.68 56.0 5.01e-01 100.0% 74.3%
2re1A02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.68 57.0 5.06e-01 100.0% 93.2%
1gmuA01 3.30.70.790 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › UreE, C-terminal domain 0.67 54.0 5.03e-01 100.0% 76.1%
3s1tA02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.66 55.0 4.77e-01 100.0% 91.3%
5i0hA02 1.20.5.4820 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.65 50.0 4.60e-01 93.8% 91.7%
5yppA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.65 53.0 4.53e-01 100.0% 80.0%
1nxiA00 3.30.70.970 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RraB-like 0.65 51.0 3.98e-01 100.0% 55.3%
1earA02 3.30.70.790 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › UreE, C-terminal domain 0.64 52.0 4.77e-01 100.0% 73.9%
1tuwA00 3.30.70.1090 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel. 0.64 54.0 4.29e-01 100.0% 74.5%
1sc6A03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.63 50.0 4.40e-01 100.0% 85.4%
5jrjA02 3.30.250.10 Alpha Beta › 2-Layer Sandwich › Rec A Protein; domain 2 › RecA protein, C-terminal domain 0.62 50.0 4.71e-01 91.7% 93.2%
1kn6A00 3.30.70.850 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Peptidase S8, pro-domain 0.61 50.0 4.50e-01 100.0% 91.8%
1zpwX00 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 49.0 4.31e-01 100.0% 73.2%
2kdoA03 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 49.0 4.30e-01 100.0% 71.2%
1xmxA03 1.10.10.680 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Hypothetical protein VC1899 (Restriction endonuclease-like) 0.60 47.0 3.97e-01 91.7% 56.2%
1t3aA00 3.90.1240.10 Alpha Beta › Alpha-Beta Complex › Zincin-like › "Metalloproteases (""zincins""), catalytic domain like" 0.58 45.0 2.67e-01 87.5% 26.0%
3l09A03 3.30.70.2670 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 45.0 4.53e-01 97.9% 93.6%
1t94B02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.57 44.0 3.60e-01 100.0% 75.6%
6k2eA01 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 46.0 4.23e-01 100.0% 89.7%
1vw4U00 3.30.1390.20 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein L30; Chain: A, › Ribosomal protein L30/L7 0.55 46.0 3.97e-01 100.0% 64.6%
2wb6A00 3.90.1150.90 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › 0.55 41.0 3.26e-01 93.8% 36.0%
3gpvA00 1.10.1660.10 Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › 0.54 44.0 3.44e-01 95.8% 46.9%
6nuiA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 39.0 2.77e-01 83.3% 29.9%
5d8cA00 1.10.1660.10 Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › 0.54 42.0 3.28e-01 93.8% 42.1%
6zhhA01 3.40.1110.10 Alpha Beta › 3-Layer(aba) Sandwich › Calcium-transporting ATPase, cytoplasmic domain N › Calcium-transporting ATPase, cytoplasmic domain N 0.53 39.0 2.76e-01 83.3% 82.2%
3a2vD02 3.30.1020.10 Alpha Beta › 2-Layer Sandwich › Antioxidant, Horf6; Chain A, domain 2 › Antioxidant, Horf6; Chain A, domain2 0.51 39.0 3.28e-01 89.6% 76.8%
2zzzA02 3.30.63.10 Alpha Beta › 2-Layer Sandwich › Guanylate Kinase phosphate binding domain › Guanylate Kinase phosphate binding domain 0.51 36.0 3.49e-01 81.2% 90.0%
2fpqA00 3.90.1240.10 Alpha Beta › Alpha-Beta Complex › Zincin-like › "Metalloproteases (""zincins""), catalytic domain like" 0.51 36.0 2.21e-01 83.3% 47.6%
ECOD (51)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3969520 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.72 62.0 5.13e-01 100.0% 87.8%
3277783 304.163.1.0 ↗ a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain 0.70 58.0 5.51e-01 100.0% 96.7%
4586587 304.7.1.0 ↗ a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors 0.68 57.0 5.40e-01 100.0% 86.7%
3284116 304.56.1.5 ↗ a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › PaaX_M 0.67 56.0 5.07e-01 100.0% 84.3%
3589166 304.3.1.0 ↗ a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.66 53.0 5.09e-01 100.0% 91.7%
5025013 304.163.1.0 ↗ a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain 0.64 53.0 5.17e-01 100.0% 89.1%
4152312 304.56.1.2 ↗ a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 0.63 52.0 4.40e-01 100.0% 67.8%
4567570 304.56.1.2 ↗ a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 0.63 52.0 4.47e-01 100.0% 71.8%
5009387 304.3.1.0 ↗ a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.62 49.0 4.74e-01 100.0% 91.7%
5007506 304.5.1.0 ↗ a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like 0.62 53.0 4.48e-01 100.0% 70.6%
5066573 304.56.1.0 ↗ a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like 0.62 52.0 4.44e-01 100.0% 74.1%
5037711 304.120.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI 0.62 50.0 4.68e-01 100.0% 89.2%
3382543 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.62 42.0 3.50e-01 72.9% 73.3%
5022748 304.56.1.2 ↗ a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 0.62 51.0 4.28e-01 100.0% 72.2%
5016129 101.1.9.75 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › DUF61 0.62 53.0 4.74e-01 100.0% 76.8%
4971803 304.56.1.2 ↗ a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 0.61 49.0 4.34e-01 100.0% 77.5%
3579672 101.1.9.0 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain 0.61 48.0 4.69e-01 93.8% 89.1%
3179612 101.1.9.0 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain 0.60 50.0 4.53e-01 97.9% 77.1%
4487906 304.56.1.2 ↗ a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 0.60 48.0 4.12e-01 100.0% 67.8%
5042208 304.56.1.2 ↗ a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 0.60 49.0 4.16e-01 100.0% 70.0%
5074705 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.60 44.0 3.80e-01 77.1% 58.7%
5004199 304.56.1.2 ↗ a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 0.60 48.0 4.05e-01 100.0% 64.2%
3646808 101.1.1.121 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_3 0.59 44.0 3.33e-01 89.6% 32.0%
4137321 304.56.1.2 ↗ a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 0.59 48.0 4.15e-01 100.0% 70.6%
3602088 101.1.9.75 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › DUF61 0.59 48.0 4.42e-01 100.0% 76.8%
4402584 304.56.1.2 ↗ a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 0.59 48.0 4.24e-01 100.0% 76.2%
4947559 304.56.1.0 ↗ a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like 0.59 48.0 4.10e-01 100.0% 70.0%
5043432 304.56.1.2 ↗ a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 0.59 47.0 4.02e-01 100.0% 67.8%
4641170 304.56.1.2 ↗ a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 0.59 48.0 4.09e-01 100.0% 70.0%
4952238 304.56.1.2 ↗ a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 0.59 49.0 4.18e-01 100.0% 74.1%
4123628 304.56.1.2 ↗ a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 0.59 49.0 4.25e-01 100.0% 78.8%
5059995 242.2.1.2 ↗ a+b two layers › Homing endonucleases-like › tRNA-intron endonuclease N-terminal domain-like › tRNA-intron endonuclease N-terminal domain-like › tRNA_int_endo_N 0.58 48.0 4.27e-01 100.0% 65.3%
5082987 242.2.1.2 ↗ a+b two layers › Homing endonucleases-like › tRNA-intron endonuclease N-terminal domain-like › tRNA-intron endonuclease N-terminal domain-like › tRNA_int_endo_N 0.58 46.0 4.18e-01 97.9% 62.7%
4929401 304.56.1.2 ↗ a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 0.58 46.0 4.14e-01 100.0% 75.0%
4235667 304.56.1.2 ↗ a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 0.58 46.0 4.03e-01 100.0% 71.8%
4197446 101.1.9.17 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › MerR_1 0.58 47.0 3.46e-01 93.8% 38.5%
4663993 304.56.1.2 ↗ a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 0.58 47.0 4.07e-01 100.0% 72.9%
3242025 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.57 39.0 3.23e-01 70.8% 82.4%
3384077 101.1.2.396 ↗ alpha arrays › HTH › HTH › winged helix domain › WHD_ROQ1 0.57 41.0 3.46e-01 81.2% 66.7%
3387245 101.1.9.17 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › MerR_1 0.57 47.0 3.46e-01 95.8% 40.0%
4970959 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.56 43.0 3.95e-01 91.7% 84.3%
4109720 101.1.2.404 ↗ alpha arrays › HTH › HTH › winged helix domain › DUF505 0.56 39.0 3.25e-01 75.0% 60.0%
3589820 101.1.9.17 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › MerR_1 0.55 44.0 3.39e-01 93.8% 40.8%
1844183 101.1.9.17 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › MerR_1 0.55 45.0 3.40e-01 95.8% 40.9%
4090636 101.1.9.0 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain 0.55 43.0 3.93e-01 93.8% 74.3%
4470278 101.1.9.82 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › MerR-DNA-bind, MerR_1 0.54 44.0 3.46e-01 95.8% 45.2%
4034096 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.53 39.0 3.49e-01 87.5% 77.5%
4965087 101.1.2.909 ↗ alpha arrays › HTH › HTH › winged helix domain › DUF5797 0.52 37.0 3.40e-01 79.2% 78.6%
3204193 101.1.2.86 ↗ alpha arrays › HTH › HTH › winged helix domain › SMC_Nse1 0.52 36.0 2.66e-01 75.0% 65.7%
4998335 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.50 37.0 3.41e-01 89.6% 86.7%
5079127 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.50 38.0 3.49e-01 93.8% 82.7%
D5 medium residues 225-276
PDB
Domain cluster: representative
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6ay1A00 3.30.70.141 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleoside diphosphate kinase-like domain 0.56 46.0 3.54e-01 100.0% 81.2%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4028688 2484.1.1.2 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin 0.56 42.0 3.07e-01 100.0% 26.1%
3671317 4205.1.1.0 ↗ a+b two layers › SMI1/KNR4-like › SMI1/KNR4-like › SMI1/KNR4-like 0.54 42.0 3.02e-01 86.5% 28.2%
4509286 5.1.4.254 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40, Beta-prop_NOL10_N 0.51 40.0 2.53e-01 94.2% 25.9%
D6 medium residues 285-369
PDB
Domain cluster: representative
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6pqmA01 2.60.260.20 Mainly Beta › Sandwich › HSP40/DNAj peptide-binding domain › Urease metallochaperone UreE, N-terminal domain 0.68 29.0 3.36e-01 74.1% 52.4%
3gkuA03 3.30.1370.50 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › R3H-like domain 0.62 37.0 4.02e-01 90.6% 70.4%
6g0nA01 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.60 51.0 3.37e-01 96.5% 32.2%
2zdiB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.59 37.0 3.45e-01 70.6% 50.9%
1u6gC00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.57 49.0 2.76e-01 100.0% 11.3%
7bqiA01 1.20.58.900 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain 0.56 44.0 3.65e-01 83.5% 97.4%
1f2uB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 40.0 3.39e-01 100.0% 44.8%
2qlzA02 6.10.250.2960 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.54 30.0 3.06e-01 71.8% 53.5%
2wpvE00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 44.0 3.11e-01 100.0% 27.9%
2qvaA01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.52 44.0 3.97e-01 100.0% 77.5%
1qhdA02 1.10.1350.10 Mainly Alpha › Orthogonal Bundle › Viral capsid alpha domain › Viral capsid alpha domain 0.52 38.0 2.85e-01 88.2% 29.5%
3nkgA00 2.60.120.790 Mainly Beta › Sandwich › Jelly Rolls › 0.51 31.0 2.57e-01 80.0% 29.4%
2nr7A00 1.20.141.10 Mainly Alpha › Up-down Bundle › Chitosanase, subunit A; domain 1 › Chitosanase, subunit A, domain 1 0.51 36.0 2.81e-01 74.1% 94.8%
1fpqA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.50 38.0 3.37e-01 82.4% 68.2%
ECOD (29)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3940062 2007.2.3.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase 0.62 33.0 2.27e-01 71.8% 13.3%
3716557 75.1.1.1 ↗ beta barrels › Cyclophilin-like › Cyclophilin-like › Cyclophilin-like › Pro_isomerase 0.62 51.0 3.72e-01 92.9% 69.6%
3863649 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 43.0 2.81e-01 100.0% 17.0%
3506749 633.21.1.23 ↗ alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 0.59 46.0 3.80e-01 85.9% 66.7%
3703430 4193.1.1.0 ↗ alpha arrays › RUN domain › RUN domain › RUN domain 0.58 47.0 3.72e-01 88.2% 96.6%
3364208 109.4.1.883 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.58 40.0 2.67e-01 100.0% 17.2%
3614763 192.2.1.1 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.57 39.0 3.49e-01 70.6% 76.7%
3553091 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.57 50.0 3.84e-01 100.0% 61.5%
3169451 109.4.1.3193 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HAT, Suf, HAT_Syf1_CNRKL1_C, HAT_Syf1_CNRKL1_N, HAT_PRP39_N 0.56 46.0 2.79e-01 100.0% 11.8%
3990521 5050.1.1.31 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › SLC52_ribofla_tr 0.55 43.0 3.40e-01 83.5% 67.4%
4937220 2003.1.9.1 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Activating enzymes of the ubiquitin-like proteins › ThiF 0.55 33.0 2.54e-01 89.4% 23.9%
3975813 223.3.1.2 ↗ a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Peptidase_S11 0.55 38.0 3.10e-01 72.9% 44.7%
3880336 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.54 48.0 3.28e-01 100.0% 44.9%
3234725 387.1.5.13 ↗ few secondary structure elements › omega toxin-like › omega toxin-related › Scorpion toxin-like › Antimicrobial25 0.54 32.0 3.70e-01 91.8% 81.0%
3498945 109.4.1.291 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PUF_NOP9 0.53 45.0 2.81e-01 100.0% 17.5%
4982549 2498.1.1.0 ↗ mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.53 42.0 3.03e-01 88.2% 61.5%
4490186 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.53 47.0 3.13e-01 100.0% 39.7%
3879591 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.53 47.0 3.17e-01 100.0% 42.2%
4958444 2004.1.1.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.53 39.0 3.00e-01 78.8% 65.5%
4993815 242.1.1.0 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.52 39.0 3.99e-01 78.8% 87.1%
3574038 109.4.1.235 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SRP68 0.52 46.0 2.88e-01 100.0% 21.2%
3240839 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.52 42.0 2.88e-01 90.6% 59.1%
3909510 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.52 46.0 3.06e-01 100.0% 36.9%
4382259 3926.1.1.1 ↗ alpha bundles › V-type proton ATPase subunit D › V-type proton ATPase subunit D › V-type proton ATPase subunit D › ATP-synt_D 0.52 35.0 2.73e-01 70.6% 92.5%
4020501 109.4.1.1255 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N, Cnd1 0.52 46.0 2.71e-01 100.0% 64.0%
None — 0.51 42.0 3.09e-01 90.6% 34.5%
3879741 109.4.1.192 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.51 43.0 2.64e-01 98.8% 21.4%
3519344 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.50 37.0 2.60e-01 81.2% 76.4%
5010592 101.1.2.68 ↗ alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc34 0.50 36.0 3.23e-01 88.2% 53.3%