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OR159654.1__WKW85177.1__SEA_AIKOY__15__00015

Bact-Vir

OR159654.1__WKW85177.1__SEA_AIKOY__15__00015

Identity

Accession:
OR159654 ↗
Kingdom:
phage

Quality

64.1 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 38-129
PDB
Domain cluster: representative
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2khmA01 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.69 48.0 4.61e-01 72.8% 70.4%
5ko4A00 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.65 45.0 4.38e-01 71.7% 91.1%
3f4mA00 1.20.1440.160 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like 0.61 45.0 3.84e-01 79.3% 80.5%
1irxA05 1.10.10.350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.60 45.0 4.58e-01 81.5% 100.0%
3a11B01 1.20.120.420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 0.59 46.0 4.19e-01 84.8% 66.4%
4fxdA05 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.57 41.0 3.75e-01 73.9% 66.7%
1a41A02 1.20.120.380 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Type 1-topoisomerase catalytic fragment, domain 2 0.57 39.0 3.91e-01 70.7% 89.4%
2ja2A05 1.10.10.350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.56 41.0 4.05e-01 79.3% 95.9%
2b9sA02 1.10.10.41 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Yeast DNA topoisomerase - domain 1 0.55 40.0 4.07e-01 77.2% 81.6%
1v1gA00 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.54 39.0 3.22e-01 77.2% 91.0%
1bxiA00 1.10.1200.20 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Colicin E immunity protein 0.54 37.0 3.92e-01 71.7% 85.5%
2vwaA00 1.20.58.1330 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Plasmodium falciparum UIS3 membrane protein 0.54 48.0 4.76e-01 100.0% 91.9%
2og9A01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.52 39.0 3.57e-01 81.5% 70.0%
2pgeA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.52 38.0 3.44e-01 76.1% 73.2%
2kj8A00 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.52 42.0 3.95e-01 98.9% 70.3%
6wgyA02 1.10.230.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450-Terp; domain 2 › Cytochrome P450-Terp, domain 2 0.52 37.0 3.60e-01 77.2% 68.3%
1w5sA01 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.51 36.0 3.67e-01 73.9% 81.8%
ECOD (23)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
184733 3640.1.1.1 alpha duplicates or obligate multimers › Minor ampullate fibroin 1 C-terminal domain › Minor ampullate fibroin 1 C-terminal domain › Minor ampullate fibroin 1 C-terminal domain › Spidroin_MaSp 0.69 48.0 4.21e-01 72.8% 55.0%
3869172 5000.3.1.0 alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death 0.68 54.0 4.53e-01 85.9% 76.2%
4023505 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.68 46.0 4.63e-01 70.7% 73.7%
3652177 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.65 45.0 4.50e-01 71.7% 71.3%
3646654 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.65 45.0 4.11e-01 71.7% 55.0%
3973793 2004.1.1.42 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE 0.64 45.0 2.92e-01 72.8% 28.3%
3664835 101.1.1.121 alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_3 0.64 44.0 4.00e-01 71.7% 55.2%
3420021 101.1.1.121 alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_3 0.63 43.0 3.94e-01 70.7% 52.8%
4937693 3352.1.1.2 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › PMT_2 0.63 44.0 3.01e-01 73.9% 63.1%
3442072 101.1.1.121 alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_3 0.63 44.0 3.94e-01 71.7% 52.8%
3641442 101.1.1.121 alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_3 0.63 44.0 4.21e-01 71.7% 64.8%
3789417 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.62 44.0 4.15e-01 75.0% 60.9%
4675322 101.8.1.2 alpha arrays › HTH › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › Anticodon_2 0.62 48.0 3.96e-01 82.6% 70.6%
4174559 101.8.1.2 alpha arrays › HTH › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › Anticodon_2 0.59 46.0 3.86e-01 84.8% 69.7%
3578362 101.1.1.4 alpha arrays › HTH › HTH › Three-helical HTH › PAX 0.59 39.0 4.26e-01 72.8% 85.3%
4964086 2004.1.1.1218 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PilB3_C 0.58 43.0 2.77e-01 80.4% 30.3%
4954779 5065.1.1.1 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › ABC-3 0.58 43.0 3.21e-01 80.4% 94.5%
2036569 101.1.1.91 alpha arrays › HTH › HTH › Three-helical HTH › Sap1_N 0.58 39.0 3.72e-01 70.7% 90.1%
4943950 3352.1.1.3 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › PMT 0.56 41.0 2.69e-01 77.2% 53.7%
3560358 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.52 40.0 3.47e-01 81.5% 97.2%
1174514 218.1.1.0 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like 0.52 38.0 3.35e-01 76.1% 67.4%
3338330 109.4.1.1260 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, PPR_long 0.52 34.0 2.23e-01 92.4% 14.2%
4509004 109.2.1.12 alpha superhelices › Repetitive alpha hairpins › alpha/alpha toroid › alpha/alpha toroid › Glyco_hydro_65m 0.51 41.0 2.64e-01 88.0% 79.6%
D2 high residues 1093-1160_1221-1334
PDB
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4fk7A00 3.90.176.10 Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 0.88 63.0 6.06e-01 73.1% 100.0%
4xsgB00 3.90.176.10 Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 0.86 62.0 5.93e-01 73.1% 100.0%
1qs1A02 3.90.176.10 Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 0.83 59.0 5.79e-01 73.1% 100.0%
1qs1A01 3.90.176.10 Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 0.80 59.0 5.69e-01 75.3% 100.0%
4h03A02 3.90.176.10 Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 0.71 60.0 5.75e-01 86.8% 100.0%
2j3vA02 3.90.176.10 Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 0.70 58.0 5.51e-01 86.3% 98.6%
1ojqA00 3.90.176.10 Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 0.70 62.0 5.85e-01 91.8% 100.0%
1gzeA00 3.90.176.10 Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 0.68 63.0 5.99e-01 95.6% 99.0%
5wtzA01 3.90.176.10 Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 0.68 59.0 5.59e-01 91.2% 98.6%
2j3xA01 3.90.176.10 Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 0.66 58.0 5.41e-01 91.2% 99.5%
1yqyA01 3.90.176.10 Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 0.65 55.0 5.24e-01 86.8% 100.0%
4xzjA01 3.90.176.10 Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 0.63 52.0 4.97e-01 85.7% 94.8%
6rarI02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.57 26.0 3.56e-01 92.9% 84.3%
4gv2A02 3.90.228.10 Alpha Beta › Alpha-Beta Complex › Phosphoenolpyruvate Carboxykinase; domain 3 › 0.51 37.0 3.59e-01 75.8% 98.1%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1562728 237.1.1.8 a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox 0.86 62.0 5.93e-01 73.1% 100.0%
4277383 237.1.1.8 a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox 0.84 64.0 5.83e-01 77.5% 100.0%
1893388 237.1.1.8 a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox 0.84 60.0 5.67e-01 72.5% 100.0%
7440 237.1.1.8 a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox 0.83 59.0 5.79e-01 73.1% 100.0%
308103 237.1.1.8 a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox 0.81 59.0 5.56e-01 74.2% 98.6%
3280971 237.1.1.8 a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox 0.74 51.0 5.51e-01 70.3% 100.0%
7442 237.1.1.8 a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox 0.70 62.0 5.85e-01 91.8% 100.0%
4061290 239.1.1.6 beta barrels › Ribosomal protein L25-like › Ribosomal protein L25-like › Ribosomal protein L25-like › tRNA-synt_1c_C2 0.70 24.0 3.83e-01 94.5% 78.1%
157262 237.1.1.8 a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox 0.70 63.0 6.00e-01 94.0% 97.6%
2034328 237.1.1.8 a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox 0.68 59.0 5.59e-01 90.7% 99.1%
2770556 237.1.1.8 a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox 0.67 59.0 5.61e-01 92.3% 100.0%
7439 237.1.1.8 a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox 0.67 60.0 5.71e-01 93.4% 100.0%
308110 237.1.1.8 a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox 0.67 58.0 5.48e-01 91.8% 100.0%
4294371 237.1.1.14 a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › Anthrax-tox_M 0.64 54.0 4.57e-01 87.9% 99.3%
1687631 237.1.1.8 a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox 0.63 52.0 4.88e-01 85.7% 90.5%
4954547 237.1.1.8 a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox 0.62 55.0 5.34e-01 92.3% 100.0%
4626477 237.1.1.8 a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox 0.58 48.0 5.00e-01 85.7% 100.0%
3485633 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.56 31.0 4.01e-01 96.7% 97.0%
4438870 239.2.1.1 beta barrels › Ribosomal protein L25-like › HisI-like › HisI-like › PRA-CH 0.51 24.0 3.00e-01 84.6% 70.0%
D3 medium residues 217-260_389-434
PDB
Domain cluster: representative
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2hujA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.58 39.0 3.58e-01 70.0% 93.6%
1t3dA01 1.10.3130.10 Mainly Alpha › Orthogonal Bundle › serine acetyltransferase, domain 1 › serine acetyltransferase, domain 1 0.55 38.0 3.31e-01 71.1% 51.4%
4kk2B00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.54 47.0 3.27e-01 100.0% 63.1%
8b70A01 1.20.1740.10 Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I 0.53 45.0 3.00e-01 100.0% 59.1%
1y1uA01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.52 39.0 3.01e-01 77.8% 80.5%
1xg2B00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.51 40.0 3.45e-01 97.8% 51.0%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.51 41.0 3.51e-01 98.9% 53.7%
3av0A01 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.51 38.0 2.87e-01 82.2% 88.4%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4997328 3962.1.1.0 alpha arrays › N-terminal helical domain in restriction-modification system methylation subunit-like › N-terminal helical domain in restriction-modification system methylation subunit › N-terminal helical domain in restriction-modification system methylation subunit 0.52 34.0 3.08e-01 92.2% 46.9%
3183672 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.50 46.0 3.87e-01 100.0% 79.3%
D4 medium residues 261-388_435-451
PDB
CATH (22)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1zarA03 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.63 42.0 4.94e-01 87.6% 100.0%
3en9A04 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.63 47.0 5.08e-01 92.4% 94.9%
1e7uA05 1.10.1070.11 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › Phosphatidylinositol 3-/4-kinase, catalytic domain 0.59 51.0 4.65e-01 93.8% 96.3%
4otpA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.56 44.0 4.47e-01 94.5% 83.2%
4xr7E01 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.54 48.0 3.77e-01 96.6% 60.1%
2ppqA02 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.53 47.0 4.13e-01 96.6% 100.0%
4bwpB01 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.53 49.0 4.05e-01 100.0% 63.6%
1yhsA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.52 46.0 4.25e-01 95.2% 90.1%
4bwkB01 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.52 47.0 3.87e-01 100.0% 62.3%
2zv2A02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.51 46.0 4.28e-01 96.6% 99.4%
5wvdB02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.51 41.0 4.37e-01 93.1% 97.6%
3s95A02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.51 44.0 4.00e-01 96.6% 96.5%
2jiiA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.51 45.0 4.05e-01 96.6% 96.0%
4y85A02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.51 44.0 4.14e-01 94.5% 97.8%
4bf2A02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.51 44.0 4.18e-01 95.2% 98.3%
3vwaA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.50 44.0 4.45e-01 94.5% 99.3%
1phkA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.50 45.0 4.13e-01 96.6% 97.3%
2wtkC02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.50 45.0 4.04e-01 96.6% 90.3%
3dxqB02 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.50 44.0 3.87e-01 95.2% 96.7%
2qkwB02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.50 44.0 3.96e-01 94.5% 97.5%
1yhvA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.50 45.0 4.04e-01 96.6% 89.2%
2pmlX02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.50 44.0 3.89e-01 96.6% 88.4%
ECOD (63)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3179497 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.63 52.0 4.09e-01 88.3% 73.1%
4013268 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.62 48.0 3.40e-01 82.1% 60.7%
5044470 206.1.1.9 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 0.62 48.0 3.94e-01 93.1% 46.8%
5018052 206.1.1.9 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 0.61 48.0 4.01e-01 89.0% 48.2%
4956602 206.1.1.9 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 0.61 48.0 3.92e-01 91.7% 45.4%
3540579 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.61 48.0 3.76e-01 82.1% 74.7%
3411446 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.61 46.0 3.51e-01 78.6% 72.7%
4261761 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.60 47.0 3.66e-01 80.7% 58.0%
3620739 206.1.1.9 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 0.60 49.0 3.74e-01 97.2% 38.4%
3593286 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.60 46.0 3.47e-01 80.7% 57.7%
3242631 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.60 47.0 3.71e-01 82.8% 62.0%
3619079 206.1.1.70 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1 0.60 43.0 3.74e-01 73.1% 70.7%
3488012 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.60 46.0 3.66e-01 80.7% 66.4%
3515869 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.59 46.0 3.41e-01 80.7% 61.9%
4028313 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.59 42.0 3.45e-01 73.1% 42.7%
5005406 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.59 53.0 4.31e-01 100.0% 65.4%
3981109 206.1.1.97 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1, WaaY 0.59 42.0 3.60e-01 97.9% 46.5%
3275956 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.58 49.0 3.78e-01 89.0% 58.1%
3470150 206.1.1.70 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1 0.58 47.0 3.68e-01 87.6% 78.2%
4962780 206.1.1.9 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 0.58 48.0 4.14e-01 100.0% 57.0%
3853147 206.1.1.74 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, PK_Tyr_Ser-Thr 0.57 48.0 3.60e-01 89.0% 54.6%
3568248 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.57 48.0 3.70e-01 89.0% 60.6%
3800964 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.57 49.0 3.66e-01 100.0% 37.7%
5054665 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.56 51.0 4.64e-01 100.0% 77.4%
3816744 206.1.1.9 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 0.56 50.0 3.82e-01 95.2% 58.7%
3412386 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.56 46.0 3.43e-01 89.0% 53.9%
3195294 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.55 39.0 3.36e-01 73.1% 58.2%
3170958 206.1.1.9 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 0.54 50.0 3.81e-01 100.0% 58.5%
3232570 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.53 49.0 3.74e-01 100.0% 58.8%
3906707 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.53 48.0 3.85e-01 100.0% 72.2%
3645432 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.52 47.0 4.11e-01 97.2% 97.2%
3166997 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.52 48.0 4.03e-01 100.0% 72.5%
3276000 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.52 48.0 3.54e-01 100.0% 62.5%
3964288 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.52 47.0 3.92e-01 100.0% 70.2%
3582203 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.52 48.0 3.83e-01 99.3% 65.8%
5077033 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.52 47.0 3.84e-01 100.0% 67.3%
3385105 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.52 48.0 3.78e-01 100.0% 66.3%
3514553 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.52 47.0 3.60e-01 100.0% 68.5%
3725022 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.52 47.0 3.69e-01 99.3% 68.0%
3512117 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.52 47.0 3.72e-01 100.0% 68.7%
3443813 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.51 47.0 3.70e-01 100.0% 59.0%
3505875 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.51 47.0 3.72e-01 100.0% 60.3%
4200907 206.1.1.87 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, RIO1 0.51 47.0 3.79e-01 100.0% 66.2%
4104048 206.1.1.70 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1 0.51 46.0 3.52e-01 100.0% 56.0%
3883849 206.1.1.70 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1 0.51 47.0 3.73e-01 100.0% 65.5%
3614882 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.51 46.0 3.69e-01 100.0% 75.6%
3256186 206.1.1.72 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, Pkinase_fungal 0.51 47.0 3.64e-01 100.0% 76.2%
3601153 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.51 47.0 3.60e-01 100.0% 57.2%
3163745 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.51 46.0 3.96e-01 99.3% 62.6%
3251693 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.51 47.0 3.45e-01 100.0% 65.5%
4018648 206.1.1.70 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1 0.51 46.0 3.52e-01 100.0% 56.2%
3540753 206.1.1.71 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, Kdo 0.51 46.0 3.71e-01 100.0% 75.9%
4485368 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.51 46.0 3.95e-01 100.0% 66.0%
3503649 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.51 46.0 3.73e-01 100.0% 66.9%
3512831 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.50 46.0 3.72e-01 100.0% 67.1%
3700463 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.50 46.0 3.66e-01 100.0% 75.2%
3240843 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.50 46.0 3.60e-01 100.0% 71.3%
None 0.50 46.0 3.62e-01 100.0% 61.5%
5079104 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.50 46.0 3.48e-01 100.0% 59.1%
3931607 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.50 46.0 3.63e-01 100.0% 78.3%
3176674 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.50 45.0 3.37e-01 100.0% 60.4%
3366990 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.50 46.0 3.59e-01 100.0% 63.9%
4023413 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.50 45.0 3.43e-01 100.0% 70.7%
D5 medium residues 477-534_560-591_614-638
PDB
D6 medium residues 824-897
PDB
Domain cluster: representative
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2d9xA01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.61 39.0 3.40e-01 83.8% 42.7%
1vw5A00 3.30.70.1420 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Structure from the mobile metagenome of cole harbour salt marsh: integron cassette protein hfx_cass1 0.61 43.0 3.42e-01 86.5% 36.4%
2k49A00 2.30.29.80 Mainly Beta › Roll › PH-domain like › 0.56 40.0 3.46e-01 75.7% 80.5%
2bg1A02 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.56 43.0 2.84e-01 83.8% 19.6%
3kk7A01 3.30.420.400 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.56 40.0 3.59e-01 77.0% 64.2%
3weeA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.55 38.0 2.86e-01 71.6% 80.3%
1nubA01 3.30.60.30 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › 0.54 26.0 2.60e-01 71.6% 36.6%
6p58A00 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.54 40.0 3.23e-01 79.7% 54.7%
5m1pB00 3.30.420.240 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.50 33.0 2.52e-01 73.0% 26.5%
ECOD (7)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4098704 4167.1.1.1 beta complex topology › Flagellar hook protein flgE D1 domain › Flagellar hook protein flgE D1 domain › Flagellar hook protein flgE D1 domain › LlgE_F_G_D1 0.63 47.0 3.79e-01 79.7% 74.5%
4498285 245.2.1.1 a+b two layers › Ribonuclease PH domain 2-like › YbaB › YbaB › YbaB_DNA_bd 0.59 42.0 3.88e-01 78.4% 58.9%
3964178 324.1.1.1 a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.54 43.0 3.54e-01 89.2% 47.4%
3987428 3843.1.1.0 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.53 43.0 3.84e-01 85.1% 100.0%
62630 4019.1.1.3 alpha complex topology › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › Transpeptidase 0.53 34.0 3.10e-01 82.4% 46.7%
3633291 7525.1.1.2 a/b three-layered sandwiches › Phosphoglycerate mutase-like › Phosphoglycerate mutase-like › Phosphoglycerate mutase-like › His_Phos_2 0.52 40.0 2.55e-01 83.8% 43.0%
3959053 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.52 35.0 2.65e-01 89.2% 28.1%
D7 medium residues 1005-1090
PDB
Domain cluster: representative
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1c9bA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.70 43.0 4.20e-01 89.5% 54.6%
2khmA01 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.67 55.0 5.14e-01 97.7% 72.2%
2rjoA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.64 39.0 3.11e-01 88.4% 30.1%
1txuA01 1.10.246.120 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.63 49.0 4.78e-01 88.4% 75.5%
2xseA00 1.20.120.1440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › JBP1, DNA-binding domain 0.63 48.0 3.90e-01 80.2% 69.2%
1aisB02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.60 39.0 3.88e-01 89.5% 60.6%
6nmnA02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.60 42.0 3.66e-01 72.1% 66.4%
1n00A03 1.10.220.10 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Annexin 0.59 37.0 4.03e-01 89.5% 75.3%
2lsgA00 1.20.58.1280 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DNA repair protein Rev1, C-terminal domain 0.59 41.0 3.95e-01 93.0% 63.9%
1wgwA00 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.59 38.0 3.66e-01 82.6% 57.6%
1m2vB01 1.20.120.730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Sec23/Sec24 helical domain 0.56 48.0 3.90e-01 97.7% 68.0%
4c0eA01 1.25.40.790 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.55 47.0 3.40e-01 100.0% 64.7%
1xdxA01 3.30.1140.40 Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › Tctex-1 0.55 44.0 4.19e-01 87.2% 85.0%
4rw0A00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.53 43.0 3.39e-01 88.4% 64.7%
4ap2B01 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.53 45.0 3.90e-01 94.2% 69.4%
3u64A00 1.25.40.920 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TRAP transporter T-component 0.52 44.0 3.13e-01 94.2% 31.7%
1kyoF00 1.10.287.20 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain 0.52 34.0 3.56e-01 79.1% 75.7%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.52 41.0 3.91e-01 87.2% 86.4%
2oerA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 43.0 3.49e-01 95.3% 71.5%
1dtoA01 1.10.287.30 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 0.52 39.0 3.70e-01 80.2% 85.3%
1b0bA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 40.0 3.49e-01 87.2% 94.3%
1urjA03 1.10.150.560 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.51 33.0 3.35e-01 83.7% 67.1%
2c61A00 3.40.50.12240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.50 43.0 2.82e-01 98.8% 28.5%
2zueA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.50 35.0 3.21e-01 80.2% 52.9%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3942162 1079.1.1.8 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › LysE 0.67 52.0 4.00e-01 82.6% 82.1%
4934635 5065.1.1.3 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › BPD_transp_2 0.66 50.0 3.55e-01 81.4% 59.6%
3364559 109.4.1.1261 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2, PPR_long 0.65 39.0 3.45e-01 88.4% 40.8%
3979656 5065.1.1.3 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › BPD_transp_2 0.63 49.0 3.44e-01 84.9% 92.9%
4963832 5069.1.1.107 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Exosortase_EpsH 0.61 43.0 3.07e-01 79.1% 23.7%
3690046 109.4.1.1317 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps53_N, VPS53_C 0.61 53.0 3.18e-01 100.0% 29.9%
3884349 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.61 44.0 3.87e-01 75.6% 88.0%
3681327 109.4.1.883 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.58 35.0 3.28e-01 88.4% 47.2%
3446153 109.4.1.1292 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_3 0.57 39.0 2.83e-01 96.5% 25.4%
3457663 192.29.1.178 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF28703 0.56 45.0 4.27e-01 87.2% 75.2%
3600221 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 49.0 3.01e-01 98.8% 31.7%
3953375 142.1.1.3 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.55 38.0 3.55e-01 72.1% 60.9%
3625804 4156.1.1.0 alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like 0.52 41.0 3.58e-01 88.4% 92.1%
3374304 601.33.1.0 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain 0.52 43.0 4.42e-01 89.5% 96.2%
3350365 109.4.1.1254 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, E_motif 0.51 45.0 2.86e-01 98.8% 22.1%
D8 medium residues 1161-1220
PDB
Domain cluster: representative
CATH (32)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2j3vA02 3.90.176.10 Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 0.82 69.0 4.67e-01 100.0% 26.4%
4h03A02 3.90.176.10 Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 0.79 70.0 4.75e-01 100.0% 28.7%
5wtzA01 3.90.176.10 Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 0.75 68.0 4.57e-01 100.0% 28.2%
1c9bA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.64 46.0 3.95e-01 76.7% 55.7%
1qs1A01 3.90.176.10 Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 0.64 54.0 3.85e-01 100.0% 69.0%
4heoA00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.63 33.0 3.46e-01 78.3% 56.4%
5afdA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.61 43.0 2.78e-01 75.0% 18.0%
2dodA00 1.10.10.440 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain 0.61 43.0 3.96e-01 76.7% 76.8%
4exjA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.59 45.0 3.59e-01 100.0% 40.5%
1gkuB03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 41.0 2.93e-01 73.3% 95.0%
8gtyA02 3.30.420.150 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Exopolyphosphatase. Domain 2 0.59 52.0 3.76e-01 100.0% 81.5%
2zxqA06 1.20.1270.70 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle 0.59 39.0 3.85e-01 98.3% 63.6%
2mw8A00 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.58 45.0 4.34e-01 83.3% 85.1%
8h4pA01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.58 47.0 3.05e-01 93.3% 67.5%
2qyuA02 1.25.40.300 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Putative secreted effector protein 0.58 43.0 3.07e-01 90.0% 25.1%
2dceA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.58 39.0 3.75e-01 73.3% 86.8%
2jvwA01 1.10.720.30 Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › SAP domain 0.58 40.0 4.06e-01 75.0% 73.3%
4wr4A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 44.0 3.66e-01 100.0% 47.6%
5hayA02 1.25.40.440 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Nucleoporin, helical domain, central subdomain 0.57 40.0 3.70e-01 96.7% 57.0%
5a4uF02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 42.0 3.43e-01 100.0% 40.5%
2zcaA00 1.10.520.40 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › CRISPR-associated protein Cse2 0.56 45.0 3.41e-01 90.0% 78.7%
3bjbD00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 47.0 3.41e-01 95.0% 37.4%
4ri6A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.55 38.0 3.13e-01 100.0% 37.0%
3rpzA00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.55 45.0 2.95e-01 91.7% 89.9%
1z1vA00 1.10.150.50 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 0.54 39.0 3.72e-01 76.7% 85.7%
1lk3A00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.54 45.0 3.58e-01 98.3% 67.6%
8b0qA02 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.52 35.0 3.57e-01 70.0% 86.7%
2p0nA00 1.20.120.520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like 0.52 42.0 3.20e-01 100.0% 34.8%
3pffA05 3.40.50.261 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Succinyl-CoA synthetase domains 0.51 38.0 2.76e-01 80.0% 80.6%
1u97A00 1.10.287.1130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › CytochromE C oxidase copper chaperone 0.51 35.0 3.42e-01 93.3% 65.2%
4ielA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.50 40.0 3.32e-01 91.7% 56.9%
2jaqA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.50 40.0 2.82e-01 86.7% 46.0%
ECOD (26)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1893388 237.1.1.8 a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › ADPrib_exo_Tox 0.83 73.0 4.94e-01 100.0% 28.2%
3473294 101.1.1.67 alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_6 0.65 44.0 4.16e-01 71.7% 76.0%
3486574 101.1.1.50 alpha arrays › HTH › HTH › Three-helical HTH › Nop16 0.59 44.0 4.45e-01 81.7% 88.3%
3966077 101.26.1.1 alpha arrays › HTH › Tex N-terminal domain › Tex N-terminal domain › Tex_N 0.59 47.0 4.53e-01 90.0% 97.1%
3459209 632.2.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains 0.59 37.0 3.78e-01 80.0% 65.0%
4989822 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.58 43.0 4.47e-01 78.3% 98.2%
4148402 102.1.1.24 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › HHH_2 0.58 43.0 3.95e-01 80.0% 80.0%
5048105 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.57 49.0 3.18e-01 98.3% 45.9%
3691242 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.56 49.0 3.46e-01 100.0% 48.3%
184691 130.2.1.1 alpha arrays › LEM/SAP HeH motif-like › PF09905 (DUF2132) › PF09905 (DUF2132) › VF530 0.56 40.0 3.67e-01 78.3% 56.1%
3609215 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.56 40.0 3.66e-01 100.0% 57.5%
3972538 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.56 38.0 3.21e-01 73.3% 44.2%
4013993 2004.1.1.366 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NPHP3_N 0.56 45.0 3.18e-01 95.0% 68.6%
3987996 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.55 40.0 3.84e-01 78.3% 82.9%
993558 102.1.1.16 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › SAM_2 0.55 39.0 3.66e-01 75.0% 86.8%
3511797 605.6.1.0 alpha duplicates or obligate multimers › ROP-like › HP1531-like › HP1531-like 0.55 43.0 4.28e-01 96.7% 83.1%
3603105 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.55 38.0 3.62e-01 75.0% 84.0%
3673226 622.2.1.0 alpha bundles › YvfG-like › YvfG-like › YvfG-like 0.53 40.0 4.16e-01 90.0% 89.1%
4180014 101.1.1.70 alpha arrays › HTH › HTH › Three-helical HTH › SANT_DAMP1_like 0.52 44.0 4.09e-01 100.0% 78.8%
2983212 568.1.1.4 few secondary structure elements › p8-MTCP1-related › p8-MTCP1-related › p8-MTCP1-related › CHCH 0.52 36.0 2.73e-01 98.3% 26.4%
3517909 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.52 37.0 4.04e-01 76.7% 100.0%
5044657 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.51 41.0 4.19e-01 95.0% 93.3%
3665835 150.3.1.33 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › DUF594 0.51 43.0 3.10e-01 100.0% 37.4%
3946360 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.51 40.0 3.99e-01 90.0% 83.1%
3416035 104.1.1.0 alpha duplicates or obligate multimers › TFIIA, alpha-helical domain › TFIIA, alpha-helical domain › TFIIA, alpha-helical domain 0.51 40.0 4.15e-01 85.0% 96.4%
3668207 109.4.1.1258 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2 0.50 37.0 2.71e-01 83.3% 27.9%