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OR195044.1__WNM72224.1__SEA_GUSANITA_3__00003
Bact-VirOR195044.1__WNM72224.1__SEA_GUSANITA_3__00003
Identity
- Accession:
- OR195044 ↗
- Kingdom:
- phage
Quality
79.7
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 26-100
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05119.18 best | Terminase_4 | 50.1 | 4.30e-13 | 97.3% | 77.5% |
CATH (37)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1fxkB00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.78 | 57.0 | 4.94e-01 | 76.0% | 65.1% |
| 6k6iA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.74 | 60.0 | 4.25e-01 | 98.7% | 29.7% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.74 | 60.0 | 3.99e-01 | 86.7% | 68.7% |
| 4fxxB01 | 6.10.140.1790 | Special › Helix non-globular › Helix Hairpins › | 0.72 | 54.0 | 5.51e-01 | 77.3% | 90.3% |
| 3rh9A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.72 | 50.0 | 3.35e-01 | 73.3% | 20.1% |
| 1rq0A01 | 6.10.140.160 | Special › Helix non-globular › Helix Hairpins › | 0.69 | 59.0 | 5.75e-01 | 92.0% | 96.4% |
| 2j6lA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.69 | 49.0 | 3.23e-01 | 73.3% | 19.7% |
| 4iggB06 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.69 | 60.0 | 4.23e-01 | 93.3% | 36.7% |
| 3rkgA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.68 | 50.0 | 3.90e-01 | 78.7% | 37.8% |
| 2yqyA00 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.67 | 46.0 | 3.87e-01 | 70.7% | 67.5% |
| 5k3hB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.66 | 54.0 | 4.37e-01 | 100.0% | 48.9% |
| 1l8dA00 | 1.10.287.510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.66 | 47.0 | 4.27e-01 | 76.0% | 65.0% |
| 1b8bA00 | 3.20.70.20 | Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › | 0.65 | 45.0 | 2.73e-01 | 73.3% | 78.4% |
| 2hg2A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.65 | 45.0 | 3.06e-01 | 73.3% | 20.3% |
| 8amqA02 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.64 | 57.0 | 3.61e-01 | 100.0% | 23.4% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.64 | 45.0 | 4.46e-01 | 76.0% | 76.8% |
| 2rhmC00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.63 | 49.0 | 3.60e-01 | 82.7% | 44.2% |
| 3rv0C02 | 1.10.1520.10 | Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain | 0.63 | 45.0 | 3.67e-01 | 76.0% | 41.0% |
| 1gwcA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.60 | 46.0 | 3.82e-01 | 85.3% | 44.7% |
| 1f0jA00 | 1.10.1300.10 | Mainly Alpha › Orthogonal Bundle › Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b › 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain | 0.60 | 51.0 | 3.38e-01 | 100.0% | 61.5% |
| 4rflA02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.59 | 49.0 | 3.68e-01 | 100.0% | 35.7% |
| 1lkxC03 | 1.20.120.720 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Myosin VI head, motor domain, U50 subdomain | 0.59 | 43.0 | 3.89e-01 | 78.7% | 89.7% |
| 5fq4A00 | 1.25.40.390 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.59 | 41.0 | 2.58e-01 | 74.7% | 83.6% |
| 4n1yB00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.59 | 51.0 | 3.68e-01 | 100.0% | 48.0% |
| 7wu7501 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.58 | 42.0 | 3.61e-01 | 77.3% | 97.6% |
| 3tixA02 | 6.10.140.1690 | Special › Helix non-globular › Helix Hairpins › | 0.57 | 40.0 | 3.98e-01 | 80.0% | 69.6% |
| 3d85C00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.56 | 46.0 | 3.89e-01 | 98.7% | 52.6% |
| 2r8wA00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.55 | 46.0 | 3.18e-01 | 97.3% | 43.8% |
| 2j82A00 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.54 | 44.0 | 3.16e-01 | 89.3% | 64.7% |
| 6fjxA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.54 | 43.0 | 2.94e-01 | 86.7% | 69.4% |
| 1s9qA00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.52 | 44.0 | 3.28e-01 | 100.0% | 49.6% |
| 1s7hA02 | 3.30.70.930 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.52 | 32.0 | 3.10e-01 | 85.3% | 56.1% |
| 4mndA02 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.51 | 41.0 | 3.12e-01 | 90.7% | 46.1% |
| 1kgqA01 | 1.10.166.10 | Mainly Alpha › Orthogonal Bundle › Tetrahydrodipicolinate-N-succinyltransferase; Chain A, domain 1 › Tetrahydrodipicolinate-N-succinyltransferase, N-terminal domain | 0.51 | 40.0 | 4.19e-01 | 97.3% | 94.3% |
| 2qwwC00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 37.0 | 3.13e-01 | 80.0% | 76.8% |
| 1t90A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.50 | 40.0 | 2.77e-01 | 88.0% | 68.6% |
| 5g5gA02 | 1.10.150.120 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › [2Fe-2S]-binding domain | 0.50 | 44.0 | 4.15e-01 | 100.0% | 80.0% |
ECOD (66)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4030787 | 605.1.1.303 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Terminase_4 | 0.86 | 80.0 | 7.14e-01 | 100.0% | 77.0% |
| 3411883 | 604.1.1.63 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_SESTD1 | 0.77 | 51.0 | 4.28e-01 | 76.0% | 42.5% |
| 3790375 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.76 | 55.0 | 4.59e-01 | 76.0% | 61.6% |
| 4940192 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.76 | 57.0 | 4.88e-01 | 78.7% | 87.7% |
| 3614292 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.76 | 57.0 | 4.27e-01 | 89.3% | 34.7% |
| 3716174 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.76 | 55.0 | 4.82e-01 | 76.0% | 80.9% |
| 3783976 | 192.2.1.2 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin | 0.76 | 56.0 | 5.25e-01 | 77.3% | 98.9% |
| 4948599 | 192.2.1.2 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin | 0.76 | 55.0 | 5.19e-01 | 76.0% | 73.3% |
| 4981980 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.76 | 57.0 | 4.85e-01 | 78.7% | 89.6% |
| 4025072 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.75 | 55.0 | 4.75e-01 | 77.3% | 64.3% |
| 3771989 | 192.2.1.2 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin | 0.75 | 55.0 | 4.43e-01 | 76.0% | 54.1% |
| 4972215 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.75 | 55.0 | 3.89e-01 | 76.0% | 36.7% |
| 3563976 | 601.4.1.79 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › 4HB_KIF14 | 0.73 | 61.0 | 4.69e-01 | 93.3% | 41.9% |
| 4029803 | 192.2.1.2 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin | 0.73 | 55.0 | 4.52e-01 | 78.7% | 70.0% |
| 3927737 | 632.8.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 | 0.73 | 65.0 | 5.94e-01 | 96.0% | 85.3% |
| 5002054 | 4323.1.1.0 ↗ | alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C | 0.72 | 57.0 | 4.54e-01 | 85.3% | 67.3% |
| 3732296 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.71 | 52.0 | 3.66e-01 | 100.0% | 25.1% |
| 3777935 | 5054.1.1.59 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans, Ion_trans_2 | 0.69 | 53.0 | 3.52e-01 | 81.3% | 22.1% |
| 4976469 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.69 | 62.0 | 4.10e-01 | 98.7% | 47.8% |
| 5005588 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.69 | 49.0 | 3.65e-01 | 76.0% | 61.0% |
| 3856326 | 5054.1.1.2 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans | 0.68 | 49.0 | 2.96e-01 | 77.3% | 12.0% |
| 3622196 | 604.1.1.63 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_SESTD1 | 0.68 | 50.0 | 4.23e-01 | 77.3% | 55.8% |
| 3195851 | 601.1.3.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 | 0.67 | 60.0 | 4.60e-01 | 98.7% | 89.4% |
| 3630462 | 192.2.1.2 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin | 0.67 | 49.0 | 4.02e-01 | 77.3% | 62.1% |
| 3503335 | 604.1.1.124 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_6 | 0.67 | 47.0 | 4.07e-01 | 73.3% | 48.7% |
| 4977769 | 5001.1.1.6 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Bac_rhodopsin | 0.65 | 56.0 | 4.08e-01 | 93.3% | 91.5% |
| 3730694 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.65 | 57.0 | 3.39e-01 | 93.3% | 66.3% |
| 5017106 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.65 | 58.0 | 4.55e-01 | 98.7% | 55.5% |
| 5048142 | 3281.1.1.1 ↗ | alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related › Proton_antipo_M | 0.64 | 53.0 | 3.13e-01 | 93.3% | 20.0% |
| 4025655 | 192.2.1.2 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin | 0.64 | 45.0 | 4.19e-01 | 73.3% | 95.8% |
| 3349750 | 3567.1.1.75 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › PTPLA | 0.64 | 56.0 | 4.12e-01 | 100.0% | 61.0% |
| 3939311 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.64 | 46.0 | 4.13e-01 | 77.3% | 86.4% |
| 3440194 | 601.3.1.4 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › PTPLA | 0.64 | 56.0 | 4.08e-01 | 100.0% | 59.5% |
| 5028061 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.64 | 46.0 | 4.39e-01 | 77.3% | 85.6% |
| 3674097 | 605.4.1.11 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › ALMT | 0.64 | 52.0 | 4.78e-01 | 97.3% | 69.5% |
| 3939641 | 2484.1.1.104 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_1 | 0.63 | 44.0 | 3.11e-01 | 72.0% | 94.5% |
| 3242789 | 633.23.1.14 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › Claudin_3 | 0.63 | 53.0 | 4.21e-01 | 94.7% | 56.2% |
| 4662222 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.63 | 45.0 | 3.87e-01 | 76.0% | 54.2% |
| 3972174 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.62 | 45.0 | 3.48e-01 | 77.3% | 40.0% |
| 3735230 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.62 | 53.0 | 4.14e-01 | 93.3% | 51.6% |
| 5081050 | 4275.1.1.11 ↗ | alpha arrays › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like › SU10_adaptor | 0.61 | 55.0 | 4.05e-01 | 100.0% | 85.5% |
| 2832541 | 5001.1.1.6 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Bac_rhodopsin | 0.61 | 54.0 | 3.83e-01 | 97.3% | 88.9% |
| 3602143 | 3755.3.1.305 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Rad50_zn_hook | 0.61 | 43.0 | 3.10e-01 | 76.0% | 47.5% |
| 4950368 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.61 | 52.0 | 4.12e-01 | 97.3% | 45.8% |
| 3862747 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.61 | 43.0 | 4.15e-01 | 74.7% | 71.8% |
| 4511999 | 604.1.1.63 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_SESTD1 | 0.60 | 52.0 | 3.29e-01 | 98.7% | 33.5% |
| 4937551 | 4018.1.1.2 ↗ | a+b two layers › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › Inositol_P | 0.60 | 45.0 | 3.27e-01 | 78.7% | 53.0% |
| 3544534 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.60 | 42.0 | 4.20e-01 | 74.7% | 76.2% |
| 3985490 | 192.2.1.5 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › DUF4376 | 0.59 | 43.0 | 3.74e-01 | 78.7% | 72.6% |
| 4464635 | 604.12.1.16 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › SFXNs | 0.59 | 50.0 | 3.67e-01 | 100.0% | 42.2% |
| 3717247 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.58 | 48.0 | 3.52e-01 | 93.3% | 47.3% |
| 4033272 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.58 | 45.0 | 3.93e-01 | 86.7% | 65.0% |
| 3538512 | 3892.1.1.0 ↗ | alpha bundles › Transhydrogeanse domain II › Transhydrogeanse domain II › Transhydrogeanse domain II | 0.57 | 51.0 | 4.00e-01 | 100.0% | 61.9% |
| 3775826 | 4016.1.1.0 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase | 0.57 | 51.0 | 4.08e-01 | 100.0% | 68.3% |
| 4005987 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.56 | 40.0 | 3.39e-01 | 74.7% | 95.2% |
| 3373616 | 604.12.1.68 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › DUF6857 | 0.56 | 44.0 | 3.34e-01 | 85.3% | 37.2% |
| 3470423 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.55 | 45.0 | 3.17e-01 | 93.3% | 28.7% |
| 5059049 | 247.1.1.1 ↗ | a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B | 0.55 | 46.0 | 3.10e-01 | 92.0% | 29.2% |
| 4950678 | 3843.1.1.0 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K | 0.54 | 44.0 | 4.21e-01 | 89.3% | 76.7% |
| 3440522 | 5069.1.3.12 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DUF6490 | 0.53 | 45.0 | 4.25e-01 | 100.0% | 88.4% |
| 4635289 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.53 | 43.0 | 2.72e-01 | 90.7% | 21.7% |
| 5037317 | 3110.1.1.19 ↗ | a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3 | 0.52 | 45.0 | 2.72e-01 | 98.7% | 20.5% |
| 4044429 | 1197.1.1.1 ↗ | alpha bundles › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › G3P_acyltransf | 0.51 | 45.0 | 3.19e-01 | 100.0% | 32.2% |
| 5052301 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.51 | 40.0 | 3.38e-01 | 100.0% | 46.9% |
| 3561709 | 5054.1.1.59 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans, Ion_trans_2 | 0.51 | 46.0 | 2.79e-01 | 100.0% | 19.4% |
| 3988998 | 632.19.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A › RICH | 0.51 | 41.0 | 4.04e-01 | 93.3% | 81.2% |
D2
high
residues 116-179
Domain cluster:
representative
CATH (28)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1yvwA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.81 | 53.0 | 4.68e-01 | 71.9% | 46.7% |
| 2rklF00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.78 | 52.0 | 5.63e-01 | 73.4% | 84.6% |
| 1kf6C00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.77 | 54.0 | 4.23e-01 | 73.4% | 40.0% |
| 3k17A02 | 3.30.70.890 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain | 0.74 | 56.0 | 4.35e-01 | 82.8% | 39.3% |
| 3ls1A00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.73 | 64.0 | 5.09e-01 | 100.0% | 51.1% |
| 3rkoG00 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.71 | 49.0 | 4.23e-01 | 71.9% | 48.0% |
| 3buxB01 | 1.20.930.20 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain | 0.70 | 62.0 | 4.94e-01 | 100.0% | 82.2% |
| 4errB00 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 49.0 | 4.57e-01 | 75.0% | 59.0% |
| 6fhoA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.70 | 52.0 | 3.69e-01 | 81.2% | 34.0% |
| 1lm3B00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.70 | 59.0 | 5.11e-01 | 100.0% | 69.8% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.69 | 60.0 | 4.72e-01 | 100.0% | 54.9% |
| 7p5hB03 | 1.20.1440.230 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain | 0.69 | 54.0 | 4.89e-01 | 100.0% | 61.8% |
| 3c5iA02 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.69 | 59.0 | 3.98e-01 | 100.0% | 58.7% |
| 3s84A02 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.69 | 60.0 | 4.57e-01 | 100.0% | 78.3% |
| 6q9jB02 | 1.20.1440.230 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain | 0.68 | 54.0 | 4.84e-01 | 100.0% | 62.5% |
| 2qffA00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.65 | 54.0 | 5.21e-01 | 100.0% | 82.4% |
| 1lujB01 | 1.10.10.490 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Beta-catenin-interacting ICAT | 0.64 | 42.0 | 4.57e-01 | 81.2% | 81.1% |
| 3etvA01 | 1.10.287.3290 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.63 | 56.0 | 5.12e-01 | 100.0% | 95.2% |
| 1m5iA00 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.61 | 42.0 | 3.65e-01 | 73.4% | 82.9% |
| 1n5uA02 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.60 | 50.0 | 4.61e-01 | 100.0% | 76.7% |
| 1kxpD01 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.58 | 48.0 | 4.52e-01 | 100.0% | 87.2% |
| 4gdxA02 | 1.10.246.130 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Gamma-glutamyltranspeptidase, large (L) subunit, C-terminal domain | 0.58 | 49.0 | 4.09e-01 | 93.8% | 66.7% |
| 4wesB03 | 1.20.89.10 | Mainly Alpha › Up-down Bundle › Nitrogenase Molybdenum-iron Protein, subunit B; domain 4 › Nitrogenase Molybdenum-iron Protein, subunit B, domain 4 | 0.58 | 40.0 | 3.77e-01 | 73.4% | 74.7% |
| 1lwbA00 | 1.20.90.10 | Mainly Alpha › Up-down Bundle › Phospholipase A2 › Phospholipase A2 domain | 0.56 | 45.0 | 3.81e-01 | 96.9% | 59.8% |
| 6dcjA02 | 1.25.40.650 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.55 | 44.0 | 3.87e-01 | 93.8% | 84.6% |
| 2i53A02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.55 | 47.0 | 4.00e-01 | 100.0% | 57.7% |
| 1eu8A02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.53 | 45.0 | 3.19e-01 | 98.4% | 74.2% |
| 3c4wB01 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.53 | 45.0 | 3.26e-01 | 100.0% | 61.4% |
ECOD (35)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3997912 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.81 | 74.0 | 6.01e-01 | 100.0% | 61.7% |
| 4436335 | 3390.1.1.0 ↗ | extended segments › Photosystem II reaction center protein T, PsbT › Photosystem II reaction center protein T, PsbT › Photosystem II reaction center protein T, PsbT | 0.76 | 51.0 | 5.91e-01 | 70.3% | 100.0% |
| 3475770 | 5069.1.1.38 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Frag1 | 0.76 | 67.0 | 4.91e-01 | 100.0% | 45.3% |
| 5009682 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.76 | 67.0 | 5.46e-01 | 100.0% | 57.5% |
| 4057506 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.75 | 63.0 | 5.63e-01 | 100.0% | 65.6% |
| 4542315 | 304.1.1.1 ↗ | a+b two layers › Alpha-beta plaits › GHMP Kinase, C-terminal domain › GHMP Kinase, C-terminal domain › GHMP_kinases_C | 0.75 | 58.0 | 4.36e-01 | 82.8% | 36.9% |
| 5035274 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.75 | 66.0 | 5.36e-01 | 100.0% | 66.7% |
| 3600055 | 633.6.1.0 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like | 0.74 | 65.0 | 5.27e-01 | 100.0% | 76.0% |
| 4049273 | 3710.1.1.1 ↗ | alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 | 0.74 | 59.0 | 5.76e-01 | 84.4% | 85.7% |
| 4949593 | 3718.1.1.0 ↗ | alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT | 0.74 | 52.0 | 4.55e-01 | 73.4% | 50.5% |
| 3925326 | 601.11.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0.73 | 65.0 | 4.75e-01 | 100.0% | 40.0% |
| 4648372 | 3390.1.1.0 ↗ | extended segments › Photosystem II reaction center protein T, PsbT › Photosystem II reaction center protein T, PsbT › Photosystem II reaction center protein T, PsbT | 0.72 | 49.0 | 5.58e-01 | 70.3% | 100.0% |
| 1557160 | 5001.1.1.6 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Bac_rhodopsin | 0.72 | 63.0 | 4.10e-01 | 100.0% | 27.7% |
| 3634546 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.72 | 59.0 | 5.69e-01 | 100.0% | 80.0% |
| 3668496 | 632.1.1.17 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Sas10_Utp3 | 0.71 | 64.0 | 5.51e-01 | 100.0% | 80.0% |
| 3356723 | 611.7.1.15 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Rx_N | 0.71 | 62.0 | 5.07e-01 | 98.4% | 81.7% |
| 5044068 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.71 | 62.0 | 5.46e-01 | 100.0% | 76.8% |
| 3937183 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.70 | 62.0 | 4.77e-01 | 100.0% | 49.0% |
| 4398992 | 150.1.1.3 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin | 0.70 | 61.0 | 3.82e-01 | 100.0% | 90.1% |
| 3801706 | 3817.1.1.1 ↗ | alpha bundles › Peroxisomal biogenesis factor 19 › Peroxisomal biogenesis factor 19 › Peroxisomal biogenesis factor 19 › Pex19 | 0.70 | 62.0 | 4.93e-01 | 100.0% | 57.4% |
| 5046322 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.69 | 62.0 | 5.76e-01 | 100.0% | 82.5% |
| 5016324 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.69 | 58.0 | 5.13e-01 | 100.0% | 64.2% |
| 3684359 | 604.7.1.0 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A | 0.69 | 61.0 | 4.69e-01 | 100.0% | 57.9% |
| 3253939 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.69 | 59.0 | 4.88e-01 | 100.0% | 65.0% |
| 2038540 | 3817.1.1.1 ↗ | alpha bundles › Peroxisomal biogenesis factor 19 › Peroxisomal biogenesis factor 19 › Peroxisomal biogenesis factor 19 › Pex19 | 0.69 | 60.0 | 4.69e-01 | 98.4% | 66.2% |
| 4218530 | 5038.2.1.1 ↗ | alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like › MAPEG | 0.68 | 59.0 | 4.73e-01 | 100.0% | 48.9% |
| 3179731 | 130.1.2.1 ↗ | alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › ribosome-binding domain of Mdm38 › LETM1_RBD | 0.68 | 52.0 | 3.92e-01 | 89.1% | 34.7% |
| 3835373 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.68 | 58.0 | 4.54e-01 | 100.0% | 52.7% |
| 3286912 | 632.18.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 | 0.67 | 59.0 | 5.23e-01 | 100.0% | 68.4% |
| 3737481 | 3817.1.1.1 ↗ | alpha bundles › Peroxisomal biogenesis factor 19 › Peroxisomal biogenesis factor 19 › Peroxisomal biogenesis factor 19 › Pex19 | 0.65 | 56.0 | 4.50e-01 | 100.0% | 47.4% |
| 3270156 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.63 | 43.0 | 3.09e-01 | 70.3% | 24.2% |
| 3669274 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.62 | 51.0 | 4.16e-01 | 100.0% | 52.1% |
| 4580987 | 3636.1.1.0 ↗ | a+b two layers › XPD arch domain › XPD arch domain › XPD arch domain | 0.60 | 53.0 | 3.99e-01 | 100.0% | 50.0% |
| 3605535 | 4952.1.1.0 ↗ | alpha arrays › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like | 0.59 | 50.0 | 4.40e-01 | 93.8% | 72.6% |
| 4290562 | 7014.1.1.1 ↗ | alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA | 0.54 | 45.0 | 3.80e-01 | 92.2% | 56.4% |