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OR339795.1__WNL49444.1__X__00095

Bact-Vir

OR339795.1__WNL49444.1__X__00095

Identity

Accession:
OR339795 ↗
Kingdom:
phage

Quality

81.6 mean pLDDT

Taxonomy

Heunggongvirae› Uroviricota› Caudoviricetes› Punavirus› Escherichia_phage_phi456

TaxID: 3075925

Cluster

View cluster (2 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 76-275
PDB
Domain cluster: rep: MK064563__AZI75768.1__SBFV2-gp01__00001__D223-383
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00270.36 best DEAD 26.3 7.90e-06 94.0% 88.0%
PF04851.22 ResIII 67.7 1.60e-18 91.5% 82.9%
D2 high residues 588-648
PDB
Domain cluster: representative
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1uyvB02 3.90.226.10 Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 0.67 51.0 3.29e-01 83.6% 19.6%
7ankB03 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.59 38.0 3.66e-01 75.4% 54.7%
1dgfA03 1.20.1370.60 Mainly Alpha › Up-down Bundle › Hemocyanin, N-terminal domain › 0.59 42.0 3.51e-01 77.0% 73.7%
3ivpD01 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.58 47.0 4.47e-01 91.8% 76.0%
1x4pA00 1.10.10.790 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Surp module 0.55 38.0 3.76e-01 83.6% 68.2%
2n1fA00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.55 42.0 3.81e-01 88.5% 93.3%
2z16B01 1.20.91.10 Mainly Alpha › Up-down Bundle › Influenza Virus Matrix Protein; Chain A, domain 1 › Influenza matrix M1, N-terminal subdomain 1 0.53 37.0 3.49e-01 75.4% 96.2%
3axbA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.52 42.0 2.90e-01 95.1% 87.5%
4mmoA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 39.0 3.00e-01 86.9% 92.8%
7lt2A01 3.30.460.90 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › 0.51 38.0 2.67e-01 88.5% 62.4%
ECOD (9)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3173844 101.1.15.0 ↗ alpha arrays › HTH › HTH › HAT1, C-terminal domain 0.69 46.0 4.17e-01 75.4% 50.6%
3987241 308.2.1.0 ↗ a+b two layers › ClpS-like › Penicillin binding protein ClpS-like domain › Penicillin binding protein ClpS-like domain 0.59 45.0 3.49e-01 83.6% 94.5%
3575456 145.1.1.3 ↗ alpha arrays › F-box domain › F-box domain › F-box domain › F-box-like 0.59 39.0 3.53e-01 82.0% 47.8%
3489807 108.1.1.17 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_11 0.56 38.0 3.62e-01 75.4% 58.7%
3895660 108.1.1.0 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand 0.53 42.0 3.95e-01 90.2% 72.0%
3262871 1128.1.1.1 ↗ alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR 0.52 42.0 4.05e-01 95.1% 90.7%
3601443 206.1.1.20 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.52 38.0 2.46e-01 82.0% 49.3%
3962271 7523.1.1.0 ↗ a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II 0.52 42.0 3.07e-01 98.4% 30.8%
3890430 110.1.1.0 ↗ alpha arrays › DEATH domain › DEATH domain › DEATH domain 0.52 41.0 3.68e-01 96.7% 72.0%
D3 high residues 685-777
PDB
Domain cluster: representative
CATH (3)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2hv2A01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.61 28.0 2.81e-01 72.0% 42.1%
4mtlA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.60 32.0 2.51e-01 97.8% 22.6%
1dusA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.60 34.0 2.67e-01 96.8% 25.8%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3271024 2003.1.5.73 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_16 0.64 34.0 2.68e-01 97.8% 24.2%
5080277 246.2.1.1 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.60 36.0 2.66e-01 100.0% 23.0%
3480623 284.1.3.0 ↗ a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain 0.57 33.0 3.57e-01 95.7% 65.8%
5037750 3926.1.1.1 ↗ alpha bundles › V-type proton ATPase subunit D › V-type proton ATPase subunit D › V-type proton ATPase subunit D › ATP-synt_D 0.54 32.0 2.51e-01 88.2% 28.2%
5005640 3604.1.1.1 ↗ a+b two layers › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain › Ni_insertion 0.52 30.0 3.60e-01 81.7% 83.1%
3694617 633.23.1.9 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin › SUR7 0.52 40.0 3.23e-01 86.0% 93.8%
D4 medium residues 13-75
PDB
Domain cluster: representative
CATH (32)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4zcfC01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.99 95.0 6.03e-01 100.0% 24.8%
7wq5A01 3.30.730.10 Alpha Beta › 2-Layer Sandwich › GCC-box Binding Domain › AP2/ERF domain 0.65 38.0 3.92e-01 92.1% 62.1%
4g4sO01 3.40.50.12120 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › POC1 chaperone 0.61 54.0 3.79e-01 100.0% 85.5%
1hlvA02 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.59 43.0 4.45e-01 93.7% 81.7%
6uf3A00 3.40.630.190 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › LCP protein 0.59 47.0 3.18e-01 90.5% 97.6%
2do7A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.57 37.0 3.46e-01 93.7% 52.5%
2kxeA00 1.10.8.800 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › D-family DNA polymerase, DP1 subunit N-terminal domain 0.55 32.0 3.07e-01 85.7% 48.6%
3umcD02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.55 46.0 4.28e-01 95.2% 74.4%
3dplC03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 37.0 3.43e-01 93.7% 53.0%
3tqlA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.55 39.0 3.20e-01 77.8% 92.9%
4le5A02 3.30.300.10 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.54 48.0 3.75e-01 100.0% 65.7%
3gudA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 38.0 3.23e-01 77.8% 84.9%
4rk6B02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.54 41.0 3.14e-01 82.5% 62.8%
1auvA01 3.30.1490.20 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain 0.54 30.0 3.06e-01 81.0% 53.3%
3umbA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.54 47.0 4.39e-01 98.4% 78.5%
2xi5A00 3.40.91.60 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › 0.53 40.0 3.02e-01 87.3% 84.8%
4oloB00 3.30.70.1710 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › BMC (bacterial microcompartment) domain 0.53 40.0 3.62e-01 85.7% 59.5%
2m4eA00 1.20.120.1930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF16691 family 0.53 40.0 3.59e-01 92.1% 59.3%
3umgA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.53 45.0 4.35e-01 95.2% 87.3%
4ntlA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.52 42.0 3.36e-01 92.1% 93.4%
4rk4A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 37.0 2.85e-01 74.6% 64.1%
2z61A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.52 38.0 2.72e-01 81.0% 76.4%
1fgsA01 3.40.1190.10 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain 0.51 46.0 2.98e-01 100.0% 85.9%
3delB01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.51 39.0 3.16e-01 87.3% 87.8%
2rh8A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 41.0 2.64e-01 87.3% 87.8%
5suhB01 3.30.70.1710 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › BMC (bacterial microcompartment) domain 0.51 43.0 3.74e-01 95.2% 61.6%
3tahA02 1.10.287.1770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.51 42.0 3.79e-01 92.1% 79.5%
8azbA01 3.10.105.10 Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 0.51 44.0 3.06e-01 98.4% 49.3%
8be0A01 3.40.91.90 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain 0.51 37.0 2.86e-01 87.3% 83.2%
1j6wA00 3.30.1360.80 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › S-ribosylhomocysteinase (LuxS) 0.51 44.0 3.34e-01 100.0% 61.5%
1pfoA01 3.90.840.10 Alpha Beta › Alpha-Beta Complex › HIV-1 Reverse Transcriptase; Chain A, domain 3 › Thiol-activated cytolysin superfamily/Thiol-activated cytolysin, alpha-beta domain 0.50 40.0 3.00e-01 93.7% 68.3%
1lkxC03 1.20.120.720 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Myosin VI head, motor domain, U50 subdomain 0.50 39.0 3.37e-01 100.0% 52.3%
ECOD (40)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1676530 2004.1.1.120 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII 0.99 95.0 6.04e-01 100.0% 25.0%
3463054 5050.1.1.108 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PUCC, Nodulin-like, NFD4_C 0.62 45.0 2.71e-01 85.7% 9.7%
86702 4325.1.1.1 ↗ mixed a+b and a/b › YegP-like › YegP-like › YegP-like › DUF1508 0.61 30.0 3.24e-01 77.8% 50.0%
3757867 211.1.1.26 ↗ a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › zf-3CxxC 0.61 47.0 3.77e-01 84.1% 72.0%
3380188 252.2.1.1 ↗ a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 0.60 36.0 3.82e-01 98.4% 67.3%
3639522 2003.1.2.15 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_3 0.59 49.0 3.22e-01 93.7% 62.1%
5016748 101.1.2.30 ↗ alpha arrays › HTH › HTH › winged helix domain › TrmB 0.59 40.0 3.30e-01 73.0% 37.5%
3724623 109.4.1.356 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.59 50.0 3.03e-01 100.0% 21.5%
3649913 5050.1.1.58 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › NFD4_C 0.58 43.0 3.31e-01 85.7% 32.4%
3287075 2003.1.2.15 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_3 0.58 48.0 3.30e-01 93.7% 57.0%
3797700 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.57 43.0 3.82e-01 85.7% 97.0%
3949260 4120.1.1.0 ↗ few secondary structure elements › Tim10/DDP › Tim10/DDP › Tim10/DDP 0.57 42.0 3.69e-01 85.7% 82.7%
3519143 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.57 49.0 3.20e-01 100.0% 53.4%
3731228 377.1.1.94 ↗ few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › ZZ 0.57 48.0 3.43e-01 92.1% 60.6%
3741967 101.1.15.1 ↗ alpha arrays › HTH › HTH › HAT1, C-terminal domain › MOZ_SAS 0.57 42.0 3.82e-01 79.4% 90.6%
4634282 304.3.1.0 ↗ a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.57 44.0 4.48e-01 85.7% 85.7%
3883105 3226.1.1.1 ↗ alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease 0.56 45.0 2.78e-01 100.0% 63.6%
3809926 2498.1.1.92 ↗ mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › DUF7906 0.56 46.0 3.13e-01 98.4% 69.6%
4233293 268.2.1.1 ↗ a+b two layers › Sterol carrier protein-like › LytR-Cps2A-Psr (LCP) enzymes › LytR-Cps2A-Psr (LCP) enzymes › LytR_cpsA_psr 0.55 47.0 3.15e-01 100.0% 96.1%
5062823 267.1.1.3 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase 0.55 45.0 3.26e-01 100.0% 74.9%
3670673 101.1.2.386 ↗ alpha arrays › HTH › HTH › winged helix domain › WH_DRP 0.54 44.0 3.72e-01 90.5% 85.5%
4475138 606.1.1.16 ↗ alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Transposase_20 0.54 42.0 3.09e-01 90.5% 51.0%
3476821 267.1.1.3 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase 0.53 43.0 2.94e-01 100.0% 77.3%
5022019 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.53 45.0 4.16e-01 93.7% 76.2%
4862494 5100.1.1.1 ↗ extended segments › iron-sulfur center-binding helical hairpin › iron-sulfur center-binding helical hairpin › iron-sulfur center-binding helical hairpin › NADH-G_4Fe-4S_3 0.53 39.0 3.65e-01 81.0% 83.1%
3550392 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.53 40.0 2.97e-01 85.7% 89.7%
3814341 304.3.1.0 ↗ a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.52 40.0 4.14e-01 98.4% 98.2%
3463392 304.3.1.0 ↗ a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.52 40.0 4.03e-01 98.4% 84.6%
3293450 304.3.1.1 ↗ a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA 0.52 40.0 3.96e-01 100.0% 77.1%
5010738 101.1.2.30 ↗ alpha arrays › HTH › HTH › winged helix domain › TrmB 0.52 38.0 3.18e-01 79.4% 74.6%
None — 0.52 38.0 3.35e-01 77.8% 76.7%
4437052 167.1.1.1 ↗ alpha arrays › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal_S7 0.51 36.0 2.85e-01 76.2% 43.3%
3674421 304.3.1.1 ↗ a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA 0.51 40.0 3.88e-01 100.0% 77.1%
3591240 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 44.0 3.08e-01 96.8% 59.5%
3480825 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.51 42.0 3.81e-01 95.2% 77.8%
4014842 304.3.1.0 ↗ a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.51 39.0 3.95e-01 100.0% 83.1%
3734132 3542.1.1.3 ↗ alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Peptidase_A22B 0.51 37.0 2.50e-01 84.1% 85.7%
4000800 109.10.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.51 40.0 3.09e-01 92.1% 81.2%
3725600 304.3.1.1 ↗ a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA 0.51 39.0 3.91e-01 100.0% 83.1%
4257164 331.2.1.1 ↗ a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV 0.50 38.0 3.61e-01 85.7% 72.5%
D5 medium residues 294-361
PDB
Domain cluster: representative
CATH (56)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ossC00 2.30.30.830 Mainly Beta › Roll › SH3 type barrels. › 0.83 71.0 7.26e-01 94.1% 93.8%
1ybyA02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.78 50.0 5.14e-01 100.0% 68.8%
3a5zD02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.77 49.0 5.05e-01 100.0% 68.8%
2eqsA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.71 51.0 4.68e-01 100.0% 58.4%
1l0wA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.70 46.0 3.99e-01 100.0% 43.4%
3zl8A02 3.40.1190.10 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain 0.69 39.0 2.72e-01 100.0% 16.8%
5zg8A01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.68 46.0 4.04e-01 100.0% 47.1%
3tw6D02 3.10.600.10 Alpha Beta › Roll › pyruvate carboxylase f1077a mutant fold › pyruvate carboxylase f1077a mutant domain 0.68 36.0 3.51e-01 72.1% 46.1%
1azpA00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.67 43.0 4.43e-01 95.6% 68.2%
6l4qB01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.66 48.0 3.82e-01 100.0% 38.5%
1t9hA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.66 44.0 4.37e-01 100.0% 64.4%
6nrzA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.66 52.0 3.97e-01 100.0% 37.4%
4up7A01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.66 48.0 3.67e-01 100.0% 34.2%
6c6sD02 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.66 37.0 3.96e-01 100.0% 61.7%
1u5kA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.64 42.0 3.94e-01 100.0% 54.9%
2eqmA01 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.64 38.0 4.22e-01 100.0% 75.5%
3nemA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.64 44.0 3.87e-01 100.0% 47.6%
2vnuD04 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.63 54.0 5.22e-01 100.0% 83.5%
1e5pA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.62 53.0 4.21e-01 98.5% 79.2%
1ib8A02 2.30.30.180 Mainly Beta › Roll › SH3 type barrels. › Ribosome maturation factor RimP, C-terminal domain 0.61 37.0 3.77e-01 98.5% 59.7%
1v73A00 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.61 51.0 3.30e-01 94.1% 55.0%
4joiA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.61 43.0 3.42e-01 100.0% 36.2%
5bncA02 3.20.180.10 Alpha Beta › Alpha-Beta Barrel › Split barrel-like › PNP-oxidase-like 0.61 43.0 3.84e-01 85.3% 53.8%
4azpA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.60 51.0 4.20e-01 100.0% 63.4%
1cbiA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.60 50.0 4.17e-01 100.0% 64.7%
3amuA02 2.40.50.1010 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.60 40.0 3.27e-01 100.0% 35.3%
1p6pA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.59 49.0 4.20e-01 100.0% 64.8%
2egcA00 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.59 34.0 3.34e-01 91.2% 50.7%
2qmiA02 2.40.128.210 Mainly Beta › Beta Barrel › Lipocalin › Pab87 octamerisation domain 0.59 45.0 4.10e-01 88.2% 85.0%
2qq6A01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.58 42.0 3.53e-01 76.5% 100.0%
1vyfA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.58 49.0 4.05e-01 100.0% 63.7%
1lfoA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.58 48.0 4.06e-01 100.0% 71.7%
1hczA02 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.57 42.0 4.50e-01 83.8% 89.8%
1o8vA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.57 48.0 4.00e-01 100.0% 64.7%
6rarI02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.57 46.0 4.25e-01 100.0% 68.5%
2leqA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.57 47.0 3.75e-01 94.1% 77.4%
1bebA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.57 48.0 3.74e-01 97.1% 72.4%
1okjB01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.57 48.0 3.99e-01 98.5% 81.1%
6c1zA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.56 47.0 3.89e-01 100.0% 63.8%
1h10A00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.56 43.0 3.59e-01 100.0% 47.9%
4rzkA00 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.55 38.0 3.53e-01 72.1% 66.7%
6f95A01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.55 45.0 3.60e-01 95.6% 100.0%
2a6aB01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.54 45.0 3.87e-01 98.5% 85.7%
1dfvA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.53 45.0 3.45e-01 100.0% 69.9%
1xkiA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.53 43.0 3.64e-01 97.1% 87.5%
3u4zA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.52 45.0 3.83e-01 100.0% 58.7%
1ge8A00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.52 45.0 3.13e-01 97.1% 34.5%
2el8A01 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.52 42.0 3.85e-01 91.2% 79.1%
1hfeL03 3.40.950.10 Alpha Beta › 3-Layer(aba) Sandwich › Fe-only Hydrogenase (Larger Subunit); Chain L, domain 3 › Fe-only Hydrogenase (Larger Subunit); Chain L, domain 3 0.51 39.0 3.19e-01 86.8% 92.3%
3fqmA01 2.20.25.210 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › Hepatitis C NS5A, domain 1B 0.51 35.0 3.64e-01 100.0% 78.7%
1bf3A01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.51 41.0 2.84e-01 89.7% 31.7%
3fehA02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.51 44.0 3.58e-01 95.6% 61.3%
1b63A01 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.50 38.0 2.80e-01 85.3% 74.1%
3a1jB00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.50 38.0 2.59e-01 100.0% 21.2%
3q9oA01 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.50 39.0 2.86e-01 88.2% 52.3%
2xnjA01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.50 44.0 3.86e-01 100.0% 87.5%
ECOD (53)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3838561 3454.1.1.0 ↗ beta barrels › GspC HR domain/PilP-like › GspC HR domain/PilP-like › GspC HR domain/PilP-like 0.90 80.0 8.20e-01 95.6% 100.0%
3839768 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.87 81.0 4.98e-01 100.0% 20.6%
4050524 2.1.1.10 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › EFP 0.80 51.0 5.22e-01 100.0% 67.7%
4930180 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.75 45.0 4.96e-01 100.0% 74.5%
4966535 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.75 44.0 4.65e-01 100.0% 66.7%
3386077 2.4.1.0 ↗ beta barrels › OB-fold › MOP-like › MOP-like 0.74 45.0 5.25e-01 100.0% 91.1%
3408369 284.1.3.4 ↗ a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain › CCTL2_WNK 0.74 54.0 5.26e-01 77.9% 98.7%
3967510 3454.1.1.0 ↗ beta barrels › GspC HR domain/PilP-like › GspC HR domain/PilP-like › GspC HR domain/PilP-like 0.73 64.0 6.42e-01 95.6% 97.1%
3247629 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.73 52.0 4.94e-01 100.0% 63.7%
3476052 2.1.1.142 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › HROB 0.72 46.0 3.53e-01 100.0% 29.3%
4374423 2.1.1.15 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.71 48.0 3.79e-01 100.0% 34.8%
4972824 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.70 43.0 4.75e-01 100.0% 76.4%
3633647 896.1.1.0 ↗ a+b two layers › SRP9/14-like › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Signal recognition particle alu RNA binding heterodimer SRP9/14-related 0.70 41.0 4.24e-01 86.8% 61.5%
3598260 227.1.1.0 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp 0.68 42.0 3.46e-01 100.0% 33.6%
4352702 2.1.1.15 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.67 46.0 3.78e-01 100.0% 40.0%
3587260 2.1.1.262 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › PF31148 0.67 44.0 4.19e-01 100.0% 57.5%
5036639 2.1.1.15 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.66 46.0 4.03e-01 100.0% 49.0%
3244960 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.64 37.0 3.65e-01 77.9% 52.0%
4266074 394.1.1.1 ↗ few secondary structure elements › Invertebrate chitin-binding proteins › Invertebrate chitin-binding proteins › Invertebrate chitin-binding proteins › CBM_14 0.64 41.0 4.37e-01 82.4% 75.0%
4449501 2.1.1.15 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.63 43.0 3.56e-01 100.0% 40.0%
3409692 394.1.1.1 ↗ few secondary structure elements › Invertebrate chitin-binding proteins › Invertebrate chitin-binding proteins › Invertebrate chitin-binding proteins › CBM_14 0.61 39.0 4.21e-01 79.4% 78.2%
4030153 221.13.1.0 ↗ a+b two layers › beta-Grasp › Mitochondrial calcium uniporter N-terminal domain › Mitochondrial calcium uniporter N-terminal domain 0.61 55.0 4.81e-01 100.0% 97.0%
3623534 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.61 42.0 3.89e-01 73.5% 98.9%
5057683 2484.1.1.38 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › eRF1_2 0.61 51.0 4.30e-01 98.5% 92.8%
4668044 9.1.1.1 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin 0.60 51.0 4.20e-01 100.0% 65.4%
3226595 2484.1.1.162 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › F-box 0.60 49.0 3.85e-01 91.2% 69.7%
3567966 9.1.1.1 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin 0.60 50.0 4.61e-01 100.0% 85.3%
3931122 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.59 43.0 3.89e-01 100.0% 54.7%
3495619 220.1.1.22 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › FERM_C 0.59 43.0 3.66e-01 100.0% 47.3%
3862816 391.1.2.1 ↗ few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › VWC domain-related › VWC 0.59 40.0 4.20e-01 98.5% 76.6%
4941490 274.1.1.0 ↗ a+b two layers › Pili subunits › Pili subunits › Pili subunits 0.59 38.0 3.07e-01 100.0% 33.3%
5027635 274.1.1.0 ↗ a+b two layers › Pili subunits › Pili subunits › Pili subunits 0.59 37.0 3.24e-01 100.0% 39.8%
3882163 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.58 45.0 3.01e-01 100.0% 22.0%
4962202 2484.1.1.49 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hydant_A_N 0.58 49.0 3.99e-01 95.6% 91.1%
4091986 2484.1.1.37 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Pan_kinase 0.58 48.0 4.11e-01 95.6% 92.2%
5028240 274.1.1.0 ↗ a+b two layers › Pili subunits › Pili subunits › Pili subunits 0.57 35.0 2.90e-01 100.0% 32.3%
3382274 5.1.4.369 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › EMC1_C, Beta-prop_EMC1_N 0.56 45.0 2.52e-01 88.2% 9.3%
4614038 9.1.1.1 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin 0.56 46.0 3.89e-01 100.0% 64.7%
None — 0.55 45.0 2.80e-01 89.7% 21.8%
3242105 207.1.1.81 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FTH 0.54 48.0 3.46e-01 100.0% 56.0%
3805925 5.1.3.118 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_3 0.53 42.0 2.75e-01 88.2% 24.5%
4227866 2003.1.2.5 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FMO-like 0.53 43.0 2.75e-01 88.2% 23.3%
3576281 391.1.2.1 ↗ few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › VWC domain-related › VWC 0.53 36.0 3.69e-01 80.9% 72.3%
4188283 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.53 41.0 3.89e-01 100.0% 71.2%
3261637 12.1.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.53 36.0 3.70e-01 97.1% 73.8%
5043507 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.52 41.0 3.53e-01 91.2% 80.0%
5026433 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.52 46.0 3.98e-01 100.0% 65.0%
3217638 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.51 41.0 4.02e-01 91.2% 100.0%
4153542 2003.1.2.16 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_3,NAD_binding_8 0.51 42.0 2.61e-01 89.7% 64.6%
4976500 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.51 43.0 3.58e-01 98.5% 75.8%
4993106 246.2.1.9 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos_2 0.50 42.0 3.05e-01 100.0% 81.7%
3231101 207.1.1.81 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FTH 0.50 43.0 2.88e-01 94.1% 30.4%
4014932 246.2.1.0 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases 0.50 41.0 2.82e-01 100.0% 92.7%
D6 medium residues 375-504
PDB
Domain cluster: representative
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1w9cA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.60 45.0 3.33e-01 92.3% 31.5%
1ij5A02 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.60 31.0 3.52e-01 96.9% 65.3%
5lb3B02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 43.0 3.59e-01 100.0% 45.2%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.57 43.0 4.46e-01 90.0% 84.7%
5izlA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 38.0 3.47e-01 90.8% 50.0%
1orjD00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.55 37.0 3.85e-01 91.5% 71.2%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.54 40.0 4.22e-01 90.0% 85.7%
7swlB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 48.0 4.46e-01 100.0% 90.5%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.53 42.0 4.26e-01 91.5% 85.2%
4akgA15 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 43.0 4.34e-01 99.2% 88.3%
2x0nA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 37.0 3.30e-01 100.0% 50.8%
4fxdA04 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.52 36.0 3.44e-01 70.8% 93.5%
2b5dX01 3.20.110.10 Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain 0.51 45.0 3.23e-01 99.2% 85.6%
1foeA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.50 37.0 3.26e-01 76.9% 90.0%
7t85A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.50 36.0 3.39e-01 82.3% 60.2%
2x7xA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.50 42.0 4.13e-01 100.0% 84.8%
3kkbA00 1.20.120.880 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain 0.50 36.0 3.70e-01 92.3% 77.0%
1xpjA00 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.50 34.0 3.54e-01 90.0% 73.4%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3839768 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.92 87.0 6.09e-01 100.0% 36.3%
4261868 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.86 83.0 5.91e-01 100.0% 45.5%
5004463 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.82 78.0 5.67e-01 100.0% 44.4%
1854703 632.16.1.1 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › N-terminal domain of a replication restart primosome factor PriC › N-terminal domain of a replication restart primosome factor PriC › PriC 0.59 50.0 4.56e-01 91.5% 90.1%
4577904 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.58 34.0 4.19e-01 92.3% 93.8%
3583258 2004.1.1.10 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATP-synt_ab 0.57 30.0 2.93e-01 96.9% 42.6%
3719445 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.57 43.0 3.58e-01 91.5% 45.2%
4390593 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.56 35.0 4.13e-01 93.8% 95.3%
3851394 601.1.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.55 43.0 4.32e-01 92.3% 82.3%
3270762 5001.1.1.31 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › GPR180-TMEM145_TM 0.54 46.0 3.65e-01 91.5% 57.7%
1344564 601.4.1.6 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TorS_sensor_domain 0.53 34.0 4.01e-01 73.1% 95.5%
3508614 601.1.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.53 44.0 4.24e-01 89.2% 95.9%
4001485 601.1.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.52 40.0 3.97e-01 92.3% 76.4%
4975402 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.52 46.0 3.79e-01 100.0% 58.8%
3853606 601.1.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.51 37.0 3.81e-01 93.1% 80.0%
3670059 2004.1.1.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.51 39.0 4.21e-01 96.9% 98.2%
3604254 2002.1.1.0 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.50 40.0 3.10e-01 88.5% 68.5%
4987192 3684.1.1.0 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.50 41.0 4.18e-01 88.5% 91.9%
D7 medium residues 807-968
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF19778.6 best RE_endonuc 93.7 8.20e-27 69.1% 95.4%
CATH (13)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4qbnA00 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.76 44.0 5.66e-01 80.2% 98.9%
3dvoA00 3.40.91.10 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › 0.60 46.0 3.67e-01 80.9% 87.4%
4zkfA01 3.60.10.10 Alpha Beta › 4-Layer Sandwich › Deoxyribonuclease I; Chain A › Endonuclease/exonuclease/phosphatase 0.58 45.0 3.57e-01 81.5% 77.6%
2p14A00 3.40.91.50 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › 0.57 43.0 4.08e-01 77.2% 84.9%
2ewfA03 3.40.91.50 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › 0.57 44.0 3.94e-01 80.9% 73.3%
2xryA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.55 38.0 3.95e-01 92.0% 76.4%
2yfkA01 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.53 36.0 3.44e-01 74.1% 57.7%
2yv9A01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.53 27.0 3.21e-01 84.6% 69.1%
4ruwA01 3.60.10.10 Alpha Beta › 4-Layer Sandwich › Deoxyribonuclease I; Chain A › Endonuclease/exonuclease/phosphatase 0.53 41.0 3.42e-01 82.1% 81.1%
4hn3A00 3.10.570.10 Alpha Beta › Roll › sex pheromone staph- cam373 precursor fold › sex pheromone staph- cam373 precursor domain 0.52 42.0 3.40e-01 88.3% 57.5%
2qx2A00 3.10.570.10 Alpha Beta › Roll › sex pheromone staph- cam373 precursor fold › sex pheromone staph- cam373 precursor domain 0.52 41.0 3.33e-01 84.6% 61.6%
2pt7G01 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.51 25.0 3.39e-01 84.6% 92.3%
3u7iA00 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.50 40.0 3.62e-01 84.0% 93.1%
ECOD (30)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3964769 2008.1.1.78 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RE_endonuc 0.98 93.0 8.92e-01 98.1% 87.2%
3838474 2008.1.1.78 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RE_endonuc 0.90 83.0 8.05e-01 95.1% 88.0%
3838560 2008.1.1.78 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RE_endonuc 0.89 85.0 7.85e-01 98.1% 85.1%
4545641 2008.1.1.78 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RE_endonuc 0.89 81.0 7.99e-01 96.9% 90.0%
3976340 2008.1.1.31 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › VRR_NUC 0.87 82.0 7.81e-01 98.1% 86.5%
4936198 2008.1.1.78 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RE_endonuc 0.86 64.0 7.33e-01 79.6% 100.0%
4494448 2008.1.1.183 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF27227 0.65 50.0 5.41e-01 80.9% 96.3%
4670642 2008.1.1.6 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › UPF0102 0.64 41.0 4.82e-01 79.0% 92.0%
4223379 2008.1.1.6 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › UPF0102 0.60 40.0 4.67e-01 79.0% 94.8%
5038690 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.59 45.0 4.60e-01 79.0% 83.7%
3839909 2008.1.1.59 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.58 45.0 3.90e-01 80.9% 63.6%
11031 2008.1.1.40 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Endonuc-MspI 0.58 44.0 3.70e-01 77.8% 80.9%
4964811 2008.1.1.59 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.58 44.0 3.75e-01 79.0% 64.1%
3543559 2008.2.1.3 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › tRNA-intron endonuclease catalytic domain-like › tRNA-intron endonuclease catalytic domain-like › SLFN_GTPase-like 0.57 43.0 4.49e-01 92.0% 84.7%
2075264 2008.1.1.66 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › ArenaCapSnatch 0.57 42.0 3.89e-01 75.9% 66.0%
4622034 327.7.1.9 ↗ a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › SLFN_GTPase-like 0.57 47.0 4.68e-01 87.0% 85.5%
3566835 2008.1.1.125 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › SLFN_GTPase-like 0.54 46.0 4.51e-01 90.7% 84.6%
3438116 246.3.1.1 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like › Exo_endo_phos 0.54 39.0 3.47e-01 74.7% 51.7%
5058512 2008.1.1.59 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.54 42.0 3.55e-01 84.0% 66.0%
3700061 327.7.1.0 ↗ a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like 0.53 29.0 3.70e-01 85.8% 93.2%
3558536 327.7.1.9 ↗ a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › SLFN_GTPase-like 0.53 49.0 3.67e-01 100.0% 49.6%
3609046 327.7.1.0 ↗ a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like 0.53 28.0 3.65e-01 85.2% 94.1%
2116981 2008.1.1.66 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › ArenaCapSnatch 0.53 39.0 3.67e-01 74.7% 71.1%
3950933 2008.1.1.59 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.52 40.0 3.47e-01 81.5% 61.5%
5070502 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.52 39.0 4.14e-01 77.8% 100.0%
3586413 213.1.1.1 ↗ a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 0.52 37.0 4.02e-01 85.8% 89.2%
3589020 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.52 38.0 3.98e-01 80.9% 82.0%
5006562 2008.1.1.178 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › NA-iREase1 0.52 38.0 3.96e-01 77.2% 93.5%
3735206 246.3.1.1 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like › Exo_endo_phos 0.52 40.0 3.18e-01 81.5% 88.9%
3730197 327.7.1.1 ↗ a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer 0.51 26.0 3.26e-01 87.7% 82.2%