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OR420743.1__WMM95340.1__CRP125_gp37__00037

Bact-Vir

OR420743.1__WMM95340.1__CRP125_gp37__00037

Identity

Accession:
OR420743 ↗
Kingdom:
phage

Quality

84.7 mean pLDDT

Taxonomy

Heunggongvirae› Uroviricota› Caudoviricetes› Autographivirales› Actaeavirus› Roseobacter_phage_CRP-125

TaxID: 3072844

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 66-182
PDB
Domain cluster: rep: MH598799.1__AXH71712.1__P025_gp38__00038__D82-193
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1ldjA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.69 59.0 6.03e-01 94.0% 99.1%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.67 58.0 6.01e-01 94.9% 100.0%
2d2sA02 1.20.58.1220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain 0.67 46.0 4.91e-01 88.9% 82.2%
1zvuA03 1.10.268.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 0.66 41.0 3.86e-01 76.9% 51.4%
3owaB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.65 43.0 3.85e-01 76.9% 49.0%
1xoiA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.63 49.0 3.23e-01 82.1% 55.4%
2f07B00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.62 54.0 4.55e-01 94.9% 67.9%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.61 39.0 3.78e-01 74.4% 56.0%
1cm5A00 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.61 52.0 3.13e-01 91.5% 20.3%
3mnlB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.61 53.0 4.59e-01 95.7% 70.3%
4jgiA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.61 39.0 4.53e-01 75.2% 93.8%
3axjB01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.60 43.0 3.99e-01 76.1% 63.2%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.59 42.0 4.45e-01 73.5% 95.1%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.58 38.0 4.16e-01 70.9% 79.6%
1bdgA01 3.40.367.20 Alpha Beta › 3-Layer(aba) Sandwich › Hexokinase; domain 1 › 0.58 51.0 3.93e-01 99.1% 95.7%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.57 40.0 3.90e-01 74.4% 78.5%
2oi8A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 49.0 4.11e-01 95.7% 63.1%
1owaA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 39.0 4.11e-01 71.8% 78.3%
2oduA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 40.0 4.23e-01 74.4% 92.4%
1zcdA00 1.20.1530.10 Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › Na+/H+ antiporter like domain 0.56 41.0 2.89e-01 76.1% 43.9%
4dvyP01 1.10.357.130 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.55 50.0 4.20e-01 100.0% 79.2%
4n1yB00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.55 39.0 3.17e-01 73.5% 46.3%
3r6nA02 1.20.58.1060 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 47.0 4.29e-01 94.0% 97.4%
3zc0D00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 48.0 4.17e-01 100.0% 89.3%
3e6sA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.54 38.0 3.45e-01 72.6% 75.5%
3cqcA00 1.20.190.50 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 0.54 48.0 3.83e-01 100.0% 84.2%
3m9vA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.54 40.0 3.93e-01 89.7% 71.7%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.54 34.0 3.95e-01 88.9% 93.5%
2a9uA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.52 36.0 3.56e-01 89.7% 65.1%
2c5iT00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 37.0 4.03e-01 72.6% 97.9%
ECOD (37)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3699680 1075.1.2.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.72 60.0 4.80e-01 89.7% 69.1%
5035274 632.22.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.69 40.0 3.96e-01 82.1% 55.0%
4277373 4994.1.1.1 ↗ alpha duplicates or obligate multimers › EF2458-like › EF2458-like › EF2458-like › DUF1507 0.69 50.0 5.59e-01 99.1% 94.6%
3969668 3758.2.1.1 ↗ alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB 0.69 51.0 4.11e-01 78.6% 87.0%
3630257 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.66 45.0 3.89e-01 70.1% 83.3%
3708859 633.24.1.0 ↗ alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain 0.63 47.0 4.90e-01 98.3% 86.7%
5005031 5058.1.1.0 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.62 44.0 4.24e-01 76.9% 63.7%
4988860 1076.1.1.0 ↗ alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related 0.61 49.0 4.30e-01 86.3% 64.0%
4936055 604.39.1.17 ↗ alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › DUF2238 0.61 51.0 4.32e-01 94.0% 82.0%
3333602 3236.1.1.1 ↗ alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.60 55.0 3.70e-01 99.1% 41.9%
3249523 601.1.2.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.59 39.0 3.91e-01 74.4% 65.0%
3527434 6006.1.1.6 ↗ extended segments › Voltage gated calcium channel IQ domain › Voltage gated calcium channel IQ domain › Voltage gated calcium channel IQ domain › PF27661 0.59 37.0 3.33e-01 93.2% 47.1%
3619178 109.46.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Helical domain in TOPLESS related protein 2 (TPR2) › Helical domain in TOPLESS related protein 2 (TPR2) 0.58 42.0 4.21e-01 92.3% 73.3%
4940393 1075.5.1.2 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ 0.58 49.0 3.86e-01 92.3% 68.4%
3479092 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.58 43.0 4.56e-01 77.8% 97.0%
3206046 150.1.1.155 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Het-C 0.57 39.0 3.75e-01 70.9% 58.6%
3923984 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.57 40.0 4.36e-01 72.6% 100.0%
4000290 192.29.1.188 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › F_actin_bind 0.57 41.0 3.96e-01 75.2% 66.9%
3398015 603.1.1.104 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › 7tm_7 0.57 48.0 3.44e-01 94.9% 75.6%
3233324 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.56 37.0 4.16e-01 70.9% 90.6%
4631912 1075.5.1.2 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ 0.56 46.0 3.61e-01 89.7% 67.2%
3606689 1189.1.1.0 ↗ alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor 0.56 45.0 3.54e-01 87.2% 72.9%
3992995 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.56 37.0 3.96e-01 74.4% 76.7%
3373782 6155.1.1.2 ↗ alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.56 40.0 4.12e-01 75.2% 80.0%
4030532 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.55 40.0 3.46e-01 76.1% 91.9%
3221759 604.3.1.0 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.55 49.0 4.20e-01 99.1% 83.7%
3302214 109.4.1.2306 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF25999 0.54 45.0 3.86e-01 90.6% 63.9%
3788186 192.15.1.1 ↗ alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › VPS28 0.54 39.0 4.00e-01 75.2% 78.3%
3296811 109.24.1.9 ↗ alpha superhelices › Repetitive alpha hairpins › Helical domain in dedicator of cytokinesis protein 9 › Helical domain in dedicator of cytokinesis protein 9 › PF25999 0.54 46.0 3.87e-01 92.3% 63.7%
4943939 5073.1.2.0 ↗ alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain 0.54 40.0 3.08e-01 76.1% 36.2%
3989092 1076.1.1.1 ↗ alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Rce1-like 0.53 43.0 3.67e-01 85.5% 89.2%
3473214 150.1.1.1 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Ferritin 0.52 37.0 3.23e-01 72.6% 68.9%
4942070 5050.1.1.87 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › LPG_synthase_TM 0.52 43.0 3.31e-01 88.0% 48.4%
3567213 109.3.1.176 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2, Ank_3, Ank_4 0.51 46.0 3.70e-01 99.1% 51.7%
3908126 633.21.1.0 ↗ alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.51 36.0 3.46e-01 74.4% 64.3%
3938184 109.4.1.2541 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DHC_N2 0.51 45.0 3.69e-01 100.0% 83.6%
4951108 141.1.1.3 ↗ alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.50 44.0 3.46e-01 99.1% 86.4%
D2 high residues 191-302
PDB
Domain cluster: rep: MT375524.1__QLF88228.1__Gjalp_gp36__00035__D195-298
CATH (55)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1w0bA01 1.20.58.420 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP 0.75 54.0 5.94e-01 98.2% 90.2%
3anpB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.70 55.0 4.61e-01 83.9% 80.4%
4c0eA01 1.25.40.790 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.68 60.0 4.46e-01 96.4% 42.8%
4hzuS00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.68 51.0 4.47e-01 78.6% 57.9%
4g12A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.68 52.0 4.74e-01 81.2% 78.5%
4me9B00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.66 51.0 4.35e-01 82.1% 86.0%
2dg8D00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.66 49.0 4.25e-01 77.7% 85.5%
2ddhA04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.66 38.0 3.64e-01 79.5% 48.5%
1s2xA00 1.20.190.30 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › CAG pathogenicity island protein, CagZ 0.65 50.0 4.28e-01 81.2% 99.4%
3pmcA00 1.10.490.70 Mainly Alpha › Orthogonal Bundle › Globin-like › Histidine kinase N-terminal domain 0.65 49.0 4.65e-01 78.6% 79.5%
3vprA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.64 47.0 4.38e-01 77.7% 75.9%
3g7rA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.64 51.0 4.32e-01 85.7% 88.4%
1f5nA01 1.20.1000.10 Mainly Alpha › Up-down Bundle › Signaling Protein - Interferon-induced Guanylate-binding Protein 1; Chain A, domain 1 › Guanylate-binding protein, C-terminal domain 0.64 53.0 3.87e-01 88.4% 88.5%
2ibdA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.64 46.0 4.23e-01 75.9% 79.6%
8cdaC01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.63 48.0 4.75e-01 83.0% 76.1%
2b1eA04 1.20.1280.170 Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 0.62 49.0 4.77e-01 84.8% 84.3%
3b81A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.62 49.0 4.15e-01 83.9% 76.5%
3m9vA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.61 45.0 4.41e-01 78.6% 73.2%
1wkbA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.61 47.0 4.61e-01 91.1% 74.4%
3zgzA04 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.61 47.0 4.09e-01 95.5% 52.5%
1gaxA02 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.60 52.0 4.09e-01 95.5% 46.3%
1n4kA02 1.25.10.30 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › IP3 receptor type 1 binding core, RIH domain 0.59 52.0 4.79e-01 99.1% 88.5%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 48.0 4.35e-01 89.3% 92.2%
4d8mA01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.59 49.0 4.03e-01 92.9% 88.0%
3ubkB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.59 52.0 5.09e-01 100.0% 96.8%
5mi7A03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.58 46.0 3.54e-01 84.8% 66.7%
2bnlC00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.58 43.0 4.07e-01 77.7% 73.9%
6gwuD00 3.40.1050.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-carbonic Anhydrase; Chain A › Carbonic anhydrase 0.58 40.0 3.24e-01 70.5% 55.4%
3q18A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.58 48.0 4.82e-01 92.9% 96.6%
3r2qA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 46.0 4.64e-01 87.5% 91.2%
2etdA00 1.20.1440.20 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain 0.57 39.0 3.63e-01 71.4% 55.3%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.57 39.0 3.60e-01 70.5% 61.2%
1w99A01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.57 47.0 4.15e-01 92.0% 93.1%
2g7gA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 43.0 3.67e-01 83.0% 70.6%
3himA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 47.0 3.98e-01 92.0% 70.5%
3mvpA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 48.0 4.43e-01 95.5% 92.6%
5d18A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 42.0 3.56e-01 82.1% 79.2%
1lshA02 1.25.10.20 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Vitellinogen, superhelical 0.55 49.0 3.55e-01 100.0% 62.1%
3vkgA11 1.20.920.20 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › 0.55 39.0 3.99e-01 80.4% 75.5%
7qihA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 39.0 4.10e-01 96.4% 83.2%
1ekjA00 3.40.1050.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-carbonic Anhydrase; Chain A › Carbonic anhydrase 0.54 47.0 3.80e-01 95.5% 68.1%
2jexA01 1.10.287.30 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 0.53 32.0 3.48e-01 77.7% 69.8%
4k6jB00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.53 44.0 3.04e-01 95.5% 39.9%
1zu2A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 48.0 4.26e-01 100.0% 77.8%
4kvmA01 1.25.40.1040 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.53 45.0 2.95e-01 93.8% 28.3%
4gltA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 43.0 4.33e-01 90.2% 92.1%
7powA01 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.53 43.0 3.59e-01 89.3% 72.2%
1siqA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.52 37.0 3.33e-01 72.3% 69.0%
3beeA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.52 38.0 4.12e-01 94.6% 93.4%
5z96A01 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.52 38.0 3.07e-01 80.4% 36.2%
3m0fB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.52 44.0 4.27e-01 94.6% 93.5%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.52 41.0 3.87e-01 84.8% 88.8%
1egdA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.52 36.0 3.31e-01 70.5% 63.8%
5k3hB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.51 39.0 3.65e-01 79.5% 71.4%
1r2jA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.51 39.0 3.59e-01 81.2% 66.7%
ECOD (34)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5055279 1075.1.2.0 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.74 55.0 4.48e-01 77.7% 91.7%
4030397 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 64.0 4.51e-01 100.0% 51.4%
3662136 109.4.1.903 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_28 0.64 58.0 4.17e-01 100.0% 51.1%
4955893 109.10.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.64 57.0 4.72e-01 100.0% 82.0%
3606800 1075.5.1.0 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.64 56.0 4.44e-01 95.5% 74.2%
3168336 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 54.0 4.09e-01 92.0% 43.8%
4051999 1075.5.1.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.63 55.0 4.33e-01 95.5% 70.4%
3284671 1075.5.1.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.63 54.0 4.20e-01 92.0% 73.9%
3724724 109.4.1.167 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Rif1_N 0.62 53.0 3.26e-01 94.6% 29.4%
3598304 1075.5.1.0 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.62 54.0 4.37e-01 95.5% 73.0%
3224983 106.1.1.1 ↗ alpha arrays › Globin-like › Globin-like › Globin-like › Globin 0.62 45.0 3.85e-01 76.8% 70.8%
4679374 1075.5.1.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.61 53.0 4.18e-01 95.5% 68.9%
4939956 109.4.1.95 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2 0.60 43.0 3.39e-01 94.6% 33.6%
3424395 109.4.1.95 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2 0.60 41.0 4.13e-01 93.8% 70.0%
3783655 633.21.1.10 ↗ alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › MARVEL 0.60 42.0 3.82e-01 71.4% 80.7%
3414848 5025.1.1.0 ↗ extended segments › PetL subunit of the cytochrome b6f complex › PetL subunit of the cytochrome b6f complex › PetL subunit of the cytochrome b6f complex 0.59 47.0 4.51e-01 84.8% 76.9%
4397672 1075.1.2.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.59 42.0 3.51e-01 75.0% 89.8%
4974834 3843.1.1.0 ↗ alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.59 45.0 3.79e-01 81.2% 86.2%
3559310 3277.2.1.1 ↗ alpha arrays › Thymine dioxygenase JBP1 DNA-binding domain-like › a C-terminal domain in chromodomain helicase DNA-binding protein 1 › a C-terminal domain in chromodomain helicase DNA-binding protein 1 › CHD1-like_C 0.59 52.0 4.99e-01 98.2% 83.8%
4424239 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 52.0 3.52e-01 99.1% 85.0%
3943720 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 51.0 4.79e-01 99.1% 91.4%
3692941 601.14.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.57 42.0 3.54e-01 76.8% 81.1%
4142273 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.57 46.0 4.05e-01 88.4% 75.3%
3801210 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 43.0 3.38e-01 83.0% 54.2%
3633553 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 46.0 4.73e-01 92.0% 100.0%
3407576 603.1.1.101 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › 7tm_6 0.55 44.0 3.11e-01 87.5% 67.5%
4099500 1075.5.1.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.55 48.0 3.91e-01 99.1% 74.7%
3509225 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.54 45.0 4.29e-01 88.4% 86.9%
3731785 206.1.1.82 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › DUF7580 0.54 43.0 3.17e-01 85.7% 79.7%
3617829 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.53 41.0 3.95e-01 80.4% 88.0%
3429029 611.3.1.17 ↗ alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › TELO2_ARM 0.53 46.0 4.15e-01 98.2% 70.0%
4947205 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 47.0 3.92e-01 100.0% 96.5%
3708858 627.1.1.0 ↗ alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain 0.53 44.0 4.04e-01 92.9% 78.0%
5051764 622.4.1.0 ↗ alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.52 40.0 3.59e-01 80.4% 73.5%
D3 medium residues 306-377
PDB
Domain cluster: representative
CATH (63)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.88 62.0 4.24e-01 72.2% 30.0%
6r1nA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.87 61.0 5.30e-01 72.2% 56.3%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.85 59.0 5.03e-01 72.2% 67.0%
3fd9A03 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.82 57.0 5.73e-01 72.2% 74.0%
2nr4A02 1.20.58.290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. 0.82 62.0 6.76e-01 83.3% 100.0%
3onjA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.81 69.0 6.26e-01 94.4% 100.0%
2uubT00 1.20.58.110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 0.80 71.0 6.39e-01 100.0% 79.8%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.79 55.0 4.27e-01 72.2% 52.4%
1z0pA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 54.0 5.43e-01 72.2% 79.5%
1orjD00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.78 68.0 5.54e-01 93.1% 69.6%
4agsB04 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.77 68.0 5.50e-01 97.2% 97.7%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 68.0 5.05e-01 100.0% 62.9%
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.77 68.0 5.46e-01 100.0% 68.5%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.76 51.0 4.89e-01 70.8% 91.8%
3nrxA00 1.20.58.1520 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 66.0 5.56e-01 100.0% 82.1%
1vctA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.75 64.0 5.59e-01 94.4% 92.7%
2fupA00 1.20.58.300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like 0.74 66.0 5.44e-01 98.6% 88.2%
1dkxA02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.74 50.0 4.87e-01 70.8% 65.0%
6t0bc02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.73 65.0 4.80e-01 100.0% 97.9%
1m62A00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.73 63.0 5.98e-01 97.2% 96.6%
4i17A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.73 66.0 4.60e-01 100.0% 44.2%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.71 49.0 3.23e-01 72.2% 23.3%
1vcsA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.71 61.0 5.43e-01 94.4% 92.2%
2m6bA00 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.70 60.0 4.84e-01 100.0% 76.0%
4gytA00 1.20.120.740 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YgfB uncharacterised protein family PF03695 0.70 55.0 4.09e-01 86.1% 34.5%
2etdA00 1.20.1440.20 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain 0.70 53.0 4.31e-01 83.3% 99.3%
6lumG01 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.69 49.0 4.19e-01 73.6% 55.4%
4malA00 1.20.58.2200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 48.0 5.20e-01 83.3% 89.8%
3lszA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.69 55.0 4.62e-01 87.5% 69.6%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.69 59.0 5.28e-01 100.0% 94.3%
5dqqA01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.69 55.0 4.61e-01 88.9% 82.0%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.68 59.0 5.13e-01 95.8% 80.0%
2h7oA01 1.20.120.1330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Rac1-binding domain, N-terminal GTPase binding subdomain 0.68 55.0 4.69e-01 91.7% 58.5%
2pusA04 6.10.140.300 Special › Helix non-globular › Helix Hairpins › 0.67 57.0 5.01e-01 95.8% 81.5%
2ra1A03 1.20.58.770 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 50.0 5.30e-01 83.3% 96.8%
2c41C01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.67 56.0 4.49e-01 95.8% 96.6%
2odvA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 57.0 5.00e-01 100.0% 96.4%
2yinA03 1.20.58.740 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DOCK DHR2 domain, lobe C 0.66 55.0 4.66e-01 95.8% 76.6%
3bjdA01 1.10.1240.20 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Lytic transglycosylase, superhelical linker domain 0.66 52.0 4.96e-01 88.9% 76.1%
3r2cA00 1.10.940.10 Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like 0.66 53.0 4.35e-01 90.3% 86.2%
5figA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.66 54.0 4.90e-01 91.7% 75.0%
2vpzC00 1.20.1630.10 Mainly Alpha › Up-down Bundle › Formate dehydrogenase/DMSO reductase fold › Formate dehydrogenase/DMSO reductase domain 0.65 55.0 3.78e-01 93.1% 36.8%
1b48A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.65 53.0 4.73e-01 94.4% 80.7%
6vydA01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.65 55.0 3.72e-01 100.0% 38.9%
3cxbA03 1.10.1740.30 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Secreted effector protein SifA helical domain 0.64 46.0 4.42e-01 75.0% 69.1%
4k7bA00 1.20.120.1740 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Sodium ion translocating NADH-quinone reductase subunit C-like 0.64 53.0 4.70e-01 95.8% 67.6%
1wn0A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.63 54.0 4.53e-01 98.6% 62.6%
2d9dA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.63 53.0 5.01e-01 97.2% 93.3%
6n2nA01 3.40.920.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.63 44.0 3.35e-01 75.0% 92.1%
3juiA00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.62 53.0 4.02e-01 94.4% 51.1%
3k3oA02 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 52.0 4.93e-01 95.8% 100.0%
4hehA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.60 44.0 4.23e-01 79.2% 88.0%
1e3pA02 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.60 44.0 4.27e-01 80.6% 75.9%
3fbzA01 1.20.58.800 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 49.0 4.43e-01 91.7% 67.6%
3bjbD00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.59 48.0 3.76e-01 94.4% 48.9%
2ccyA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.58 49.0 4.20e-01 100.0% 86.6%
1n81A00 1.10.3030.10 Mainly Alpha › Orthogonal Bundle › Gametocyte protein Pfg27 › Gametocyte protein Pfg27 0.57 50.0 3.70e-01 97.2% 44.1%
3o4yA01 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.57 48.0 4.22e-01 94.4% 92.7%
4an8A02 1.10.132.100 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.56 48.0 4.13e-01 100.0% 82.0%
4ar9A02 1.10.390.20 Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › 0.53 38.0 3.05e-01 73.6% 78.2%
2o7gA00 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.53 42.0 3.92e-01 84.7% 75.0%
4p9fA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.51 43.0 3.49e-01 94.4% 82.6%
3onqA03 1.10.10.2840 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PucR C-terminal helix-turn-helix domain 0.51 41.0 3.38e-01 88.9% 82.4%
ECOD (45)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3575213 109.4.1.649 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF4807 0.80 73.0 5.77e-01 100.0% 82.1%
3953242 3883.1.1.1 ↗ alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.79 70.0 5.19e-01 100.0% 49.7%
3304429 604.9.1.0 ↗ alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 0.78 65.0 6.75e-01 95.8% 100.0%
5007317 2498.1.1.10 ↗ mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 0.77 65.0 4.32e-01 94.4% 97.6%
5027021 604.5.1.2 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.77 69.0 5.90e-01 100.0% 86.1%
3242192 5057.1.1.1 ↗ alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb 0.77 67.0 4.94e-01 97.2% 47.6%
4411856 632.22.1.1 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA 0.77 53.0 4.86e-01 72.2% 56.8%
4134938 601.3.1.14 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › PF27870 0.76 69.0 5.90e-01 100.0% 66.1%
4025328 603.1.1.228 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE, STX6_10_61_N 0.76 67.0 4.81e-01 100.0% 51.9%
4458494 3684.1.1.23 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › CA109-like 0.75 64.0 4.82e-01 94.4% 73.1%
3435020 109.4.1.1886 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › At5g52880_ARM 0.75 60.0 5.45e-01 94.4% 64.0%
3355898 109.4.1.1886 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › At5g52880_ARM 0.75 61.0 4.83e-01 94.4% 43.3%
3205967 5069.1.1.7 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 0.75 62.0 4.65e-01 90.3% 67.1%
3796001 3684.1.1.0 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.74 66.0 5.11e-01 100.0% 76.2%
4630202 5041.1.1.1 ↗ extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.74 51.0 4.79e-01 72.2% 82.0%
4051415 5041.1.1.1 ↗ extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.74 50.0 4.79e-01 70.8% 91.8%
3281911 601.4.1.2 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › NIT 0.74 66.0 5.55e-01 100.0% 75.0%
3697586 603.1.1.5 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N 0.74 65.0 4.97e-01 100.0% 78.2%
4236831 604.6.1.50 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › DUF2524 0.74 60.0 5.79e-01 88.9% 100.0%
3195309 604.6.1.0 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.73 60.0 5.00e-01 90.3% 92.8%
184932 5069.1.1.8 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › NrfD_2 0.72 64.0 5.16e-01 100.0% 75.7%
3495265 5057.1.1.1 ↗ alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb 0.71 62.0 4.83e-01 100.0% 75.8%
3332286 3684.1.1.2 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 0.71 62.0 4.38e-01 100.0% 63.7%
3275304 601.4.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.71 61.0 5.18e-01 100.0% 72.8%
3172105 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.71 61.0 5.34e-01 97.2% 73.6%
3481310 604.6.1.0 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.71 61.0 5.73e-01 100.0% 95.6%
3734796 5059.1.1.8 ↗ alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Mg_trans_NIPA 0.69 59.0 5.07e-01 97.2% 78.3%
5011068 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.68 51.0 4.53e-01 80.6% 69.5%
4032384 604.3.1.0 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.68 58.0 5.67e-01 98.6% 100.0%
4032823 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.68 57.0 5.57e-01 97.2% 100.0%
3925909 371.1.1.0 ↗ few secondary structure elements › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 0.67 53.0 4.84e-01 87.5% 71.0%
3404486 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.67 57.0 4.33e-01 100.0% 78.9%
3792754 621.1.1.7 ↗ alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › EMC6 0.67 58.0 4.81e-01 95.8% 72.8%
3218862 5054.1.1.0 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.67 58.0 4.44e-01 95.8% 62.4%
4940232 608.1.1.1 ↗ alpha arrays › AhpD-like › AhpD-like › AhpD-like › CMD 0.67 50.0 4.16e-01 87.5% 46.4%
3380503 109.1.1.6 ↗ alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C_2 0.66 53.0 3.75e-01 87.5% 57.2%
3634696 632.7.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.65 45.0 3.88e-01 70.8% 58.2%
3476098 603.3.1.1 ↗ alpha bundles › STAT-like › CAPPD, an extracellular domain of amyloid beta A4 protein › CAPPD, an extracellular domain of amyloid beta A4 protein › APP_E2 0.65 53.0 3.91e-01 93.1% 82.0%
2073547 621.1.1.2 ↗ alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Smg8_Smg9 0.64 52.0 5.40e-01 94.4% 98.5%
3535566 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.62 52.0 4.41e-01 95.8% 80.8%
4963637 5069.1.2.6 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Respiratory nitrate reductase 1 gamma chain › PF26448 0.62 49.0 3.88e-01 91.7% 45.3%
3320424 192.18.1.0 ↗ alpha bundles › Long alpha-hairpin › MxiH-like › MxiH-like 0.61 52.0 3.48e-01 98.6% 25.7%
3656227 633.7.1.0 ↗ alpha bundles › Bromodomain-like › Bacillus cereus metalloprotein-like › Bacillus cereus metalloprotein-like 0.58 51.0 4.22e-01 100.0% 84.6%
4592728 101.11.1.1 ↗ alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.57 47.0 4.49e-01 97.2% 100.0%
4070498 101.11.1.1 ↗ alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.53 42.0 3.98e-01 91.7% 90.0%
D4 medium residues 378-436
PDB
Domain cluster: representative
CATH (57)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4y2fA00 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.81 68.0 5.06e-01 91.5% 97.9%
2eyqA07 3.90.1150.50 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Transcription-repair-coupling factor, D7 domain 0.76 66.0 4.88e-01 96.6% 41.5%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.74 63.0 5.74e-01 94.9% 94.9%
6t0bf00 1.25.40.40 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Cytochrome c oxidase, subunit Va/VI 0.73 58.0 4.87e-01 89.8% 51.0%
1mhyG02 1.20.1280.30 Mainly Alpha › Up-down Bundle › Monooxygenase › Methane monooxygenase, gamma chain, domain 2 0.73 62.0 5.78e-01 93.2% 91.8%
2qsrA01 3.90.1150.50 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Transcription-repair-coupling factor, D7 domain 0.73 62.0 4.57e-01 96.6% 85.2%
3h20A04 1.10.1240.50 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › 0.72 56.0 4.97e-01 86.4% 70.8%
3u4qA06 3.90.320.10 Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › 0.68 50.0 3.42e-01 79.7% 21.8%
3d7iB00 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.68 52.0 4.53e-01 88.1% 56.1%
3mggA02 6.10.140.1580 Special › Helix non-globular › Helix Hairpins › 0.67 51.0 4.43e-01 81.4% 82.0%
3lpzA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.67 54.0 3.51e-01 93.2% 20.2%
3h0dB02 1.10.1200.150 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Transcriptional repressor of class III stress genes, C-terminal domain 0.67 54.0 4.80e-01 86.4% 71.6%
3qp1A00 3.30.450.80 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain 0.66 54.0 3.85e-01 91.5% 96.1%
6vvoE02 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.65 52.0 4.43e-01 89.8% 98.0%
2nn4A00 1.10.287.760 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YqgQ-like 0.65 48.0 4.79e-01 81.4% 85.5%
3onqA01 1.20.5.5100 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.65 42.0 4.74e-01 71.2% 95.2%
3pvuA02 1.10.167.10 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 0.65 48.0 4.39e-01 81.4% 81.2%
2lhrA00 1.20.58.1270 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 47.0 4.35e-01 79.7% 60.3%
5mdtA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.64 52.0 3.99e-01 94.9% 46.1%
3hibA01 1.10.3380.10 Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain 0.64 53.0 4.30e-01 94.9% 100.0%
3kfwX03 1.20.58.1460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 50.0 4.58e-01 84.7% 85.5%
4zvaA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.64 53.0 3.97e-01 93.2% 87.9%
1sxjB03 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.63 50.0 4.40e-01 89.8% 100.0%
4dloB02 1.25.40.610 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.63 50.0 4.12e-01 93.2% 50.4%
2keyA00 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.62 49.0 4.02e-01 88.1% 53.6%
2amxB00 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.62 45.0 2.82e-01 79.7% 17.4%
4g26A01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.62 48.0 3.17e-01 91.5% 19.7%
4cybD00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.62 50.0 3.72e-01 96.6% 84.2%
1ze0A01 1.20.120.700 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nitrate reductase, subunit delta (NarJ) 0.61 44.0 3.99e-01 81.4% 54.8%
1izmA00 1.20.120.740 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YgfB uncharacterised protein family PF03695 0.61 48.0 3.64e-01 93.2% 39.4%
2i6hA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.61 48.0 4.21e-01 91.5% 68.8%
1sxjE03 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.61 48.0 4.17e-01 89.8% 97.9%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.61 49.0 4.01e-01 88.1% 68.4%
2gscC00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.61 48.0 4.04e-01 91.5% 76.4%
3q9dB01 1.20.58.1050 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 48.0 4.35e-01 93.2% 96.6%
3dplC03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.60 47.0 4.32e-01 93.2% 80.7%
1x9bA00 1.20.58.290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. 0.59 43.0 4.43e-01 86.4% 88.7%
3t69A02 3.30.420.310 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 2-keto-3-deoxy-galactonokinase, C-terminal domain 0.59 52.0 3.51e-01 100.0% 27.9%
3nuwA02 3.30.420.310 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 2-keto-3-deoxy-galactonokinase, C-terminal domain 0.58 50.0 3.52e-01 100.0% 29.3%
2b6cA02 1.25.40.290 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › ARM repeat domains 0.58 47.0 4.04e-01 89.8% 54.6%
4d8mA01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.58 46.0 3.20e-01 89.8% 44.0%
3s64A00 1.10.225.10 Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like 0.58 43.0 4.02e-01 88.1% 79.0%
2r5sA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.56 45.0 4.03e-01 93.2% 61.4%
2fp1B00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.56 46.0 3.35e-01 89.8% 47.0%
1qd1B02 3.30.70.670 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Formiminotransferase, C-terminal subdomain 0.56 46.0 3.59e-01 96.6% 92.4%
4l0cA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.56 48.0 3.19e-01 98.3% 65.4%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.56 44.0 4.13e-01 89.8% 91.9%
3e4bA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.55 46.0 2.84e-01 96.6% 79.2%
4eadA01 1.20.970.10 Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 0.55 44.0 3.75e-01 93.2% 57.0%
5e9hB01 1.10.10.850 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.55 45.0 3.63e-01 98.3% 46.9%
3wvoC02 1.10.132.100 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.55 43.0 3.50e-01 91.5% 74.6%
4mk3A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.54 41.0 3.52e-01 91.5% 80.9%
1t7lB01 3.20.20.210 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › 0.54 45.0 2.80e-01 98.3% 23.3%
2ld7B00 1.20.1160.11 Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › Paired amphipathic helix 0.53 42.0 3.93e-01 88.1% 72.0%
3tt9A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.53 44.0 3.02e-01 94.9% 51.5%
2dbgA00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.50 42.0 3.54e-01 94.9% 73.8%
2f33A01 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.50 38.0 3.73e-01 91.5% 90.1%
ECOD (76)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5002758 4030.1.1.0 ↗ alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz 0.82 63.0 6.34e-01 81.4% 95.0%
3428374 109.7.1.25 ↗ alpha superhelices › Repetitive alpha hairpins › Cytochrome c oxidase subunit E › Cytochrome c oxidase subunit E › PPR 0.82 65.0 5.16e-01 86.4% 49.6%
3269361 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.81 67.0 4.52e-01 91.5% 28.1%
4486611 4354.1.1.1 ↗ a+b two layers › TRCF domain › TRCF domain › TRCF domain › TRCF 0.78 67.0 4.97e-01 96.6% 85.3%
4061283 4030.1.1.0 ↗ alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz 0.77 59.0 6.24e-01 83.1% 98.0%
3304958 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.77 68.0 4.25e-01 100.0% 20.6%
3577145 4030.1.1.0 ↗ alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz 0.77 61.0 6.29e-01 88.1% 98.2%
5059586 181.1.1.0 ↗ alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins 0.76 63.0 5.76e-01 93.2% 73.4%
4547644 109.4.1.228 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo84_C 0.76 62.0 4.22e-01 91.5% 37.7%
3645380 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.76 61.0 4.27e-01 91.5% 28.1%
3815642 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.75 62.0 4.25e-01 93.2% 40.0%
3320228 109.4.1.1285 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, DYW_deaminase, Eplus_motif, E_motif 0.75 63.0 3.58e-01 93.2% 14.1%
4238042 4354.1.1.1 ↗ a+b two layers › TRCF domain › TRCF domain › TRCF domain › TRCF 0.75 64.0 4.71e-01 96.6% 85.2%
5044421 592.2.1.0 ↗ alpha arrays › PWI domain-like › YugE-like › YugE-like 0.75 63.0 5.70e-01 93.2% 78.8%
3988220 4354.1.1.1 ↗ a+b two layers › TRCF domain › TRCF domain › TRCF domain › TRCF 0.75 63.0 4.63e-01 96.6% 80.5%
3869025 4030.1.1.3 ↗ alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › Exog_C 0.74 61.0 5.83e-01 91.5% 77.9%
4307373 4354.1.1.1 ↗ a+b two layers › TRCF domain › TRCF domain › TRCF domain › TRCF 0.74 62.0 4.69e-01 96.6% 40.7%
3324682 109.4.1.883 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.73 61.0 4.58e-01 93.2% 57.9%
3817204 109.4.1.883 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.73 61.0 4.25e-01 93.2% 44.7%
3377432 109.4.1.1254 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, E_motif 0.73 58.0 3.37e-01 86.4% 16.0%
3818955 109.4.1.1254 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, E_motif 0.73 60.0 3.45e-01 91.5% 15.0%
3668228 109.4.1.883 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.73 56.0 3.82e-01 84.7% 36.3%
3312460 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.72 54.0 4.64e-01 83.1% 49.0%
3335297 109.4.1.1279 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_long, TPR_24 0.72 57.0 3.30e-01 88.1% 53.9%
3327326 109.4.1.1254 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, E_motif 0.72 59.0 3.37e-01 91.5% 13.2%
3375856 109.4.1.1275 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_3, PPR_long, TPR_24 0.72 57.0 3.31e-01 86.4% 16.0%
3895121 4030.1.1.3 ↗ alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › Exog_C 0.72 60.0 5.87e-01 91.5% 85.7%
3831220 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.72 57.0 4.26e-01 86.4% 54.5%
3795480 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 59.0 3.66e-01 91.5% 16.9%
3808391 109.4.1.775 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 56.0 3.73e-01 88.1% 33.1%
4188577 7516.1.1.2 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.71 58.0 3.74e-01 89.8% 41.9%
3683525 109.4.1.883 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.71 57.0 3.51e-01 86.4% 15.7%
3651804 109.4.1.1520 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, DYW_deaminase, E_motif 0.70 55.0 3.22e-01 86.4% 16.3%
3298612 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.69 56.0 3.92e-01 93.2% 40.5%
3289266 4995.1.1.0 ↗ alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like 0.69 55.0 4.88e-01 86.4% 80.0%
4954612 3758.2.1.1 ↗ alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB 0.69 61.0 4.14e-01 98.3% 79.4%
3728392 138.1.1.2 ↗ alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C 0.69 53.0 4.63e-01 86.4% 97.9%
4947492 1030.1.1.0 ↗ alpha duplicates or obligate multimers › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 0.69 57.0 4.56e-01 94.9% 68.8%
5049287 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.69 52.0 4.24e-01 81.4% 50.0%
5005257 2.21.1.0 ↗ beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) 0.69 56.0 4.09e-01 93.2% 38.8%
3643366 109.4.1.621 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_3 0.69 52.0 3.55e-01 86.4% 22.3%
3311721 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.68 58.0 4.03e-01 100.0% 43.2%
3338289 109.4.1.1254 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, E_motif 0.68 55.0 3.21e-01 93.2% 14.2%
4929728 2004.1.3.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR 0.67 53.0 3.55e-01 88.1% 87.5%
3677708 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.67 53.0 4.02e-01 88.1% 54.5%
3384110 109.4.1.189 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_2 0.67 58.0 4.25e-01 100.0% 54.1%
3351960 109.4.1.2979 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_3, DYW_deaminase, Eplus_motif, E_motif 0.67 53.0 3.05e-01 89.8% 13.0%
3784009 138.1.1.2 ↗ alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C 0.66 54.0 4.70e-01 93.2% 98.9%
3383731 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.66 57.0 3.93e-01 100.0% 44.2%
3336905 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 56.0 4.08e-01 100.0% 47.4%
3802543 109.4.1.1267 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, DYW_deaminase, E_motif 0.64 51.0 2.96e-01 91.5% 14.4%
3189353 548.1.1.1 ↗ alpha duplicates or obligate multimers › GRIP domain › GRIP domain › GRIP domain › GRIP 0.64 47.0 4.98e-01 81.4% 92.0%
3492325 109.4.1.602 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Dor1 0.64 49.0 3.70e-01 89.8% 62.9%
3742193 314.1.1.9 ↗ a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA-synt_His 0.64 50.0 3.14e-01 88.1% 28.0%
3353608 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.64 51.0 3.59e-01 94.9% 39.1%
3460081 109.4.1.1374 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, TPR_24 0.64 50.0 3.65e-01 86.4% 50.0%
3646130 2003.1.5.31 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GRAS 0.63 51.0 3.39e-01 91.5% 75.7%
3340500 109.4.1.883 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.62 47.0 3.08e-01 88.1% 17.8%
3323082 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 49.0 3.22e-01 89.8% 60.0%
3452003 109.4.1.1273 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_3 0.61 48.0 3.40e-01 89.8% 41.5%
3459840 109.4.1.1271 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, TPR_24 0.61 47.0 3.30e-01 91.5% 46.1%
3223123 109.4.1.70 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID 0.60 49.0 3.88e-01 93.2% 48.9%
3720395 1075.4.1.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.59 47.0 3.03e-01 96.6% 82.0%
3260653 101.1.2.166 ↗ alpha arrays › HTH › HTH › winged helix domain › MCM6_C 0.59 45.0 4.00e-01 88.1% 96.8%
3678610 109.4.1.1671 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2, TPR_16, TPR_19 0.59 50.0 3.71e-01 100.0% 39.4%
3261980 172.1.1.1 ↗ alpha complex topology › Citrate synthase-like › Citrate synthase › Citrate synthase › Citrate_synt 0.59 47.0 3.01e-01 96.6% 59.9%
4954653 101.1.1.45 ↗ alpha arrays › HTH › HTH › Three-helical HTH › BrxA 0.58 48.0 4.62e-01 93.2% 91.4%
3602465 2007.1.14.25 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › PF27317 0.58 45.0 3.94e-01 88.1% 83.2%
3598384 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 44.0 2.89e-01 89.8% 25.2%
3368096 109.4.1.1409 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_LIN_C, ARM_LIN_2nd 0.58 48.0 2.99e-01 93.2% 36.1%
3310138 109.4.1.1409 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_LIN_C, ARM_LIN_2nd 0.57 48.0 2.79e-01 94.9% 35.0%
3680998 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 46.0 3.02e-01 96.6% 33.7%
4964824 101.1.6.44 ↗ alpha arrays › HTH › HTH › TrpR › HVO_2833_C 0.56 41.0 3.51e-01 83.1% 45.7%
3591903 109.1.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C 0.55 42.0 3.24e-01 89.8% 83.1%
3274289 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 39.0 3.00e-01 89.8% 29.1%
3181966 509.1.1.13 ↗ alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain › SAGA-Tad1 0.53 41.0 3.95e-01 93.2% 77.3%
D5 medium residues 437-524
PDB
Domain cluster: representative
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3dd9D02 6.10.140.2060 Special › Helix non-globular › Helix Hairpins › 0.74 36.0 4.96e-01 71.6% 100.0%
2no4A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.73 49.0 5.33e-01 93.2% 81.3%
2a6hF01 1.20.120.1810 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.72 55.0 4.31e-01 100.0% 39.3%
2lquA01 1.20.1420.40 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Decorin-binding protein 0.70 49.0 4.02e-01 71.6% 64.3%
3umbA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.69 49.0 5.20e-01 93.2% 82.3%
3if8B02 1.20.58.730 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 53.0 5.12e-01 95.5% 74.0%
1t6jA03 1.10.274.20 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Phenylalanine ammonia-lyase 1; domain 3 0.68 51.0 4.89e-01 100.0% 68.9%
3gi7A00 1.20.1270.180 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.64 53.0 5.04e-01 89.8% 84.5%
4akgA08 1.10.472.130 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Dynein motor, AAA2 domain, small subdomain 0.64 58.0 4.78e-01 100.0% 62.8%
2m6uA00 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.63 52.0 5.34e-01 94.3% 95.1%
7kypB01 1.10.3470.10 Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC 0.63 55.0 3.92e-01 100.0% 91.0%
1sg7A00 1.10.1740.70 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › ChaB 0.63 49.0 5.27e-01 94.3% 98.7%
3lynB00 1.20.150.10 Mainly Alpha › Up-down Bundle › Lysin › Fertilization protein 0.62 55.0 4.94e-01 100.0% 75.8%
1wrdA00 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 43.0 4.15e-01 70.5% 63.3%
3bvoA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.62 45.0 4.55e-01 76.1% 77.9%
3nbxX03 1.20.58.1510 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 42.0 4.04e-01 71.6% 68.3%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.60 49.0 4.42e-01 87.5% 68.4%
3bg2A01 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.59 48.0 3.84e-01 90.9% 51.3%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.59 48.0 4.21e-01 87.5% 61.5%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.59 36.0 3.72e-01 71.6% 63.5%
8igrI01 2.40.270.10 Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 0.59 40.0 3.21e-01 83.0% 34.7%
3o6xA02 1.20.120.1560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.58 47.0 3.93e-01 86.4% 68.9%
4hehA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.58 34.0 3.55e-01 70.5% 61.4%
1hs7A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 41.0 4.04e-01 75.0% 68.0%
1ukfA00 3.90.70.20 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.57 50.0 3.89e-01 96.6% 92.6%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.56 46.0 4.18e-01 88.6% 67.2%
2o36A01 1.20.1050.40 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Endopeptidase. Chain P; domain 1 0.56 39.0 3.47e-01 72.7% 53.9%
3m7gA02 1.10.8.1010 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.55 43.0 4.20e-01 86.4% 76.8%
1x3aA00 1.10.3970.10 Mainly Alpha › Orthogonal Bundle › BSD domain-like fold › BSD domain 0.53 33.0 3.17e-01 89.8% 54.0%
2qytA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.53 46.0 4.48e-01 98.9% 97.0%
1tj7A01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.52 39.0 3.72e-01 97.7% 68.6%
5xsoA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 28.0 2.98e-01 70.5% 57.9%
3q23A04 6.10.140.1370 Special › Helix non-globular › Helix Hairpins › 0.51 35.0 3.49e-01 75.0% 67.0%
1x04A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.51 46.0 3.54e-01 100.0% 79.5%
1ekjA00 3.40.1050.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-carbonic Anhydrase; Chain A › Carbonic anhydrase 0.51 38.0 2.92e-01 80.7% 63.3%
ECOD (44)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3207650 5076.1.1.1 ↗ alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.79 57.0 3.77e-01 73.9% 80.0%
4025852 101.1.10.0 ↗ alpha arrays › HTH › HTH › Cyclin-like 0.73 62.0 5.46e-01 98.9% 64.0%
3588971 6026.1.1.0 ↗ alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain 0.72 45.0 4.80e-01 70.5% 73.3%
3700820 101.1.10.0 ↗ alpha arrays › HTH › HTH › Cyclin-like 0.71 62.0 6.20e-01 100.0% 93.3%
3707815 101.1.10.0 ↗ alpha arrays › HTH › HTH › Cyclin-like 0.71 62.0 5.43e-01 100.0% 64.6%
3067828 142.1.1.3 ↗ alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.69 53.0 5.57e-01 100.0% 93.6%
5067753 2006.1.1.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase 0.64 59.0 4.17e-01 98.9% 34.7%
5058433 7516.1.1.2 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.64 47.0 3.18e-01 80.7% 22.0%
5067572 604.5.1.0 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.63 44.0 4.13e-01 71.6% 67.6%
3924442 604.6.1.1 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.63 43.0 3.99e-01 70.5% 57.3%
4174796 140.1.1.11 ↗ alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_1 0.63 51.0 3.95e-01 100.0% 39.5%
3912101 604.6.1.1 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.63 43.0 4.10e-01 70.5% 63.0%
3987612 162.1.1.1 ↗ alpha bundles › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD › PRD 0.62 37.0 3.61e-01 85.2% 52.0%
4218930 181.1.1.1 ↗ alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N 0.62 40.0 4.27e-01 100.0% 77.3%
4312332 622.4.1.0 ↗ alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.62 43.0 4.36e-01 71.6% 81.2%
3586442 604.6.1.1 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.61 42.0 3.91e-01 70.5% 57.3%
3528863 604.6.1.1 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.61 42.0 3.82e-01 70.5% 53.9%
3229885 4044.1.1.0 ↗ alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins 0.60 46.0 4.49e-01 87.5% 73.5%
3665769 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 41.0 3.16e-01 72.7% 31.8%
4628458 604.1.1.226 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF26877 0.59 41.0 4.25e-01 72.7% 81.2%
4355716 7015.1.1.0 ↗ alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.59 43.0 3.82e-01 94.3% 54.4%
4996069 604.10.1.0 ↗ alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac 0.58 41.0 4.08e-01 72.7% 71.1%
3792 603.1.1.6 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 0.58 41.0 4.04e-01 75.0% 68.0%
3454325 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.58 35.0 3.68e-01 93.2% 68.0%
5028471 5076.2.1.3 ↗ alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › DUF4013 0.58 46.0 3.66e-01 89.8% 83.5%
3187418 601.1.2.149 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PF30922 0.57 48.0 4.50e-01 96.6% 87.0%
3992612 604.6.1.1 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.57 39.0 3.89e-01 70.5% 73.3%
4675311 632.19.1.5 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A › TMEM208_SND2 0.57 46.0 4.16e-01 87.5% 69.2%
4942062 632.11.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.57 41.0 4.21e-01 85.2% 78.8%
3714315 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.56 39.0 3.69e-01 71.6% 61.9%
3824559 101.1.1.67 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_6 0.56 40.0 3.57e-01 75.0% 85.6%
3325067 138.1.1.1 ↗ alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › RFC1 0.55 42.0 3.80e-01 86.4% 57.6%
3279933 191.1.1.0 ↗ alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.55 48.0 4.16e-01 98.9% 97.2%
3742811 604.6.1.1 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.55 37.0 3.46e-01 70.5% 55.7%
5074956 632.11.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.55 38.0 3.97e-01 86.4% 80.0%
3547209 192.15.1.204 ↗ alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › DUF2678 0.54 44.0 4.26e-01 87.5% 77.0%
4498620 4230.1.1.3 ↗ alpha arrays › DnaD domain › DnaD domain › DnaD domain › DnaB_2 0.53 38.0 4.12e-01 97.7% 95.7%
4371240 632.7.1.55 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › DUF2605 0.53 40.0 3.96e-01 84.1% 74.7%
3650360 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.52 36.0 3.35e-01 73.9% 86.7%
3530312 2485.1.1.120 ↗ a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Strabismus 0.52 42.0 3.83e-01 96.6% 93.8%
4393454 632.15.1.6 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › DUF2678 0.51 42.0 4.04e-01 87.5% 78.0%
5050541 1075.3.1.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 0.51 45.0 3.37e-01 97.7% 85.8%
3390354 2004.1.1.23 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom 0.51 44.0 3.05e-01 94.3% 86.1%
4941192 3567.1.1.0 ↗ a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.50 39.0 3.56e-01 88.6% 60.0%