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OR576727.1__WNM70287.1__X__00194
Bact-VirOR576727.1__WNM70287.1__X__00194
Identity
- Accession:
- OR576727 ↗
- Kingdom:
- phage
Quality
70.3
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 12-90
Domain cluster:
representative
CATH (55)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4da2A02 | 3.40.1350.60 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › | 0.71 | 58.0 | 4.68e-01 | 89.9% | 97.4% |
| 2jrbA00 | 3.30.250.20 | Alpha Beta › 2-Layer Sandwich › Rec A Protein; domain 2 › L1 transposable element, C-terminal domain | 0.69 | 47.0 | 5.07e-01 | 100.0% | 84.6% |
| 3ajvC02 | 3.40.1350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › | 0.67 | 60.0 | 5.72e-01 | 97.5% | 90.1% |
| 2e52B01 | 3.40.91.70 | Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › Type II restriction endonuclease, HindIII | 0.64 | 56.0 | 4.09e-01 | 100.0% | 58.5% |
| 3ke3A01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.63 | 57.0 | 5.04e-01 | 98.7% | 88.4% |
| 6jy1A01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.62 | 58.0 | 4.78e-01 | 100.0% | 62.4% |
| 3oajA02 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.62 | 48.0 | 3.95e-01 | 93.7% | 45.8% |
| 5b7sB01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.62 | 57.0 | 4.71e-01 | 100.0% | 74.1% |
| 1svvB02 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.61 | 55.0 | 5.25e-01 | 97.5% | 90.2% |
| 4jpdA00 | 3.30.920.10 | Alpha Beta › 2-Layer Sandwich › Metal Transport, Frataxin; Chain A › Frataxin/CyaY | 0.61 | 54.0 | 4.89e-01 | 100.0% | 83.5% |
| 3qguA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.61 | 55.0 | 4.42e-01 | 97.5% | 61.8% |
| 1o4sA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.60 | 54.0 | 4.30e-01 | 97.5% | 56.3% |
| 4obuA01 | 3.90.1150.170 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › | 0.60 | 54.0 | 3.85e-01 | 100.0% | 42.3% |
| 1ax4A01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.60 | 55.0 | 4.03e-01 | 100.0% | 57.5% |
| 4iw7A01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.60 | 55.0 | 4.81e-01 | 100.0% | 73.9% |
| 3eleC01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.60 | 53.0 | 4.17e-01 | 97.5% | 51.8% |
| 1v2dA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.59 | 54.0 | 4.50e-01 | 100.0% | 64.9% |
| 2o1bA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.59 | 54.0 | 4.32e-01 | 100.0% | 59.3% |
| 2cy8A01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.59 | 54.0 | 4.02e-01 | 100.0% | 54.5% |
| 4my5D01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.59 | 54.0 | 4.24e-01 | 100.0% | 57.6% |
| 2z61A01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.59 | 52.0 | 4.12e-01 | 97.5% | 54.7% |
| 3b46A01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.59 | 51.0 | 3.99e-01 | 96.2% | 64.5% |
| 6grrB01 | 3.30.457.10 | Alpha Beta › 2-Layer Sandwich › Copper Amine Oxidase; Chain A, domain 1 › Copper amine oxidase-like, N-terminal domain | 0.59 | 50.0 | 5.02e-01 | 94.9% | 98.7% |
| 2x3lA01 | 3.90.1150.150 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › | 0.59 | 51.0 | 4.67e-01 | 96.2% | 79.0% |
| 5i92F01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.58 | 52.0 | 3.97e-01 | 97.5% | 56.8% |
| 3l8aA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.58 | 53.0 | 4.20e-01 | 100.0% | 58.3% |
| 4q05A00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.58 | 51.0 | 3.41e-01 | 100.0% | 81.0% |
| 4qt4A00 | 3.40.50.1470 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Peptidyl-tRNA hydrolase | 0.57 | 49.0 | 3.82e-01 | 100.0% | 82.0% |
| 2uz8A01 | 3.40.30.90 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › | 0.57 | 37.0 | 4.33e-01 | 96.2% | 98.1% |
| 1u08A01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.57 | 52.0 | 4.25e-01 | 100.0% | 65.5% |
| 4emyA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.57 | 50.0 | 3.97e-01 | 100.0% | 47.1% |
| 4cgyA01 | 3.40.50.140 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.57 | 48.0 | 3.83e-01 | 98.7% | 86.9% |
| 1xqaA01 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.57 | 47.0 | 4.20e-01 | 89.9% | 89.1% |
| 2douB01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.57 | 51.0 | 4.14e-01 | 100.0% | 59.1% |
| 5gvcB01 | 3.40.50.140 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.57 | 48.0 | 3.90e-01 | 98.7% | 93.3% |
| 3cbfA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.56 | 50.0 | 3.88e-01 | 100.0% | 56.0% |
| 1w7lA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.56 | 50.0 | 3.92e-01 | 97.5% | 66.9% |
| 1xmbA01 | 3.40.630.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases | 0.56 | 50.0 | 3.46e-01 | 100.0% | 86.1% |
| 6d0aA03 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.56 | 50.0 | 4.40e-01 | 100.0% | 84.3% |
| 3rq1D01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.56 | 47.0 | 3.77e-01 | 100.0% | 47.7% |
| 1yqeA01 | 3.40.630.50 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › AF0625-like | 0.55 | 46.0 | 3.67e-01 | 98.7% | 93.0% |
| 4py5A01 | 3.30.310.10 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › TATA-Binding Protein | 0.55 | 41.0 | 4.33e-01 | 81.0% | 95.8% |
| 4h7nA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.55 | 48.0 | 3.33e-01 | 98.7% | 45.2% |
| 4zm3B01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.55 | 48.0 | 4.02e-01 | 100.0% | 69.7% |
| 4lqeA00 | 3.40.1350.140 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › MepB-like | 0.55 | 45.0 | 3.67e-01 | 89.9% | 61.7% |
| 4tpsA00 | 3.30.310.250 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Sporulation inhibitor of replication protein SirA | 0.55 | 43.0 | 3.60e-01 | 88.6% | 48.6% |
| 2giaB00 | 2.30.31.40 | Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › | 0.55 | 37.0 | 3.09e-01 | 70.9% | 80.1% |
| 5cdvA01 | 3.40.350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Creatine Amidinohydrolase; Chain A, domain 1 › Creatinase/prolidase N-terminal domain | 0.54 | 40.0 | 3.49e-01 | 79.7% | 54.8% |
| 3r4qA01 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.54 | 47.0 | 3.97e-01 | 97.5% | 87.1% |
| 3g12B00 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.54 | 44.0 | 3.97e-01 | 91.1% | 85.8% |
| 2ykyB01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.54 | 47.0 | 3.60e-01 | 100.0% | 51.3% |
| 2f5tX02 | 2.30.30.690 | Mainly Beta › Roll › SH3 type barrels. › | 0.54 | 45.0 | 4.33e-01 | 92.4% | 88.9% |
| 3l44A01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.53 | 46.0 | 3.61e-01 | 100.0% | 54.1% |
| 3uh9B00 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.53 | 45.0 | 3.78e-01 | 93.7% | 77.4% |
| 2wfwA01 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.50 | 31.0 | 3.55e-01 | 81.0% | 86.2% |
ECOD (67)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4937815 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.75 | 53.0 | 5.36e-01 | 74.7% | 100.0% |
| 4967615 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.73 | 65.0 | 4.99e-01 | 100.0% | 88.8% |
| 5044163 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.69 | 62.0 | 5.34e-01 | 97.5% | 91.7% |
| 4983181 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.69 | 61.0 | 5.35e-01 | 100.0% | 90.0% |
| 5067832 | 2008.1.1.16 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat | 0.69 | 51.0 | 4.86e-01 | 79.7% | 96.8% |
| 4090404 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.69 | 60.0 | 5.42e-01 | 98.7% | 100.0% |
| 3285499 | 211.1.1.0 ↗ | a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0.68 | 41.0 | 4.76e-01 | 70.9% | 87.3% |
| 3299630 | 331.4.1.0 ↗ | a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 | 0.67 | 52.0 | 4.68e-01 | 81.0% | 82.9% |
| 3663084 | 331.4.1.0 ↗ | a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 | 0.67 | 52.0 | 4.23e-01 | 82.3% | 77.9% |
| 141372 | 2008.2.1.1 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › tRNA-intron endonuclease catalytic domain-like › tRNA-intron endonuclease catalytic domain-like › tRNA_int_endo | 0.67 | 60.0 | 5.71e-01 | 97.5% | 90.1% |
| 4956650 | 2008.2.1.1 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › tRNA-intron endonuclease catalytic domain-like › tRNA-intron endonuclease catalytic domain-like › tRNA_int_endo | 0.66 | 60.0 | 5.51e-01 | 98.7% | 90.0% |
| 4964435 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.66 | 59.0 | 5.33e-01 | 97.5% | 100.0% |
| 4087126 | 2008.2.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › tRNA-intron endonuclease catalytic domain-like › tRNA-intron endonuclease catalytic domain-like | 0.66 | 56.0 | 5.61e-01 | 97.5% | 92.5% |
| 4323357 | 3016.1.1.10 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › GDC-P | 0.65 | 56.0 | 3.52e-01 | 91.1% | 20.3% |
| 5064069 | 2008.2.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › tRNA-intron endonuclease catalytic domain-like › tRNA-intron endonuclease catalytic domain-like | 0.65 | 56.0 | 5.64e-01 | 94.9% | 92.5% |
| 4108740 | 3016.1.1.10 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › GDC-P | 0.65 | 59.0 | 5.34e-01 | 97.5% | 75.2% |
| 4949317 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.65 | 57.0 | 5.07e-01 | 96.2% | 100.0% |
| 3994712 | 3016.1.1.10 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › GDC-P | 0.65 | 59.0 | 5.40e-01 | 97.5% | 79.0% |
| 3166717 | 211.1.1.0 ↗ | a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0.65 | 38.0 | 4.19e-01 | 73.4% | 72.3% |
| 5042295 | 2008.2.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › tRNA-intron endonuclease catalytic domain-like › tRNA-intron endonuclease catalytic domain-like | 0.64 | 56.0 | 5.44e-01 | 98.7% | 95.6% |
| 4484798 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.64 | 57.0 | 5.37e-01 | 100.0% | 80.0% |
| 4985014 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.64 | 52.0 | 4.77e-01 | 89.9% | 100.0% |
| 3737151 | 3561.1.1.1 ↗ | a+b complex topology › Mediator of RNA polymerase II transcription subunit 17 › Mediator of RNA polymerase II transcription subunit 17 › Mediator of RNA polymerase II transcription subunit 17 › Med17 | 0.63 | 55.0 | 3.46e-01 | 100.0% | 22.9% |
| 4244167 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.63 | 58.0 | 5.56e-01 | 100.0% | 94.4% |
| 4997572 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.63 | 57.0 | 5.09e-01 | 100.0% | 88.2% |
| 5080670 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.62 | 58.0 | 5.52e-01 | 100.0% | 94.4% |
| 4674297 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.62 | 56.0 | 5.28e-01 | 97.5% | 84.2% |
| 2709980 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.62 | 58.0 | 5.53e-01 | 100.0% | 92.2% |
| 3918694 | 4099.1.1.10 ↗ | a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › Med1 | 0.62 | 55.0 | 5.28e-01 | 100.0% | 95.6% |
| 3850090 | 4099.1.1.19 ↗ | a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › Med14_RM8 | 0.62 | 53.0 | 4.49e-01 | 97.5% | 68.8% |
| 3760199 | 331.2.1.6 ↗ | a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › Med14_RM8 | 0.62 | 53.0 | 4.97e-01 | 97.5% | 95.0% |
| 4371942 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.62 | 56.0 | 4.82e-01 | 97.5% | 74.2% |
| 5035680 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.61 | 54.0 | 4.17e-01 | 98.7% | 56.7% |
| 3592558 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.61 | 55.0 | 5.18e-01 | 97.5% | 86.3% |
| 4977454 | 3016.1.1.1 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_1_2 | 0.61 | 55.0 | 4.54e-01 | 98.7% | 90.7% |
| 1005590 | 3561.1.1.0 ↗ | a+b complex topology › Mediator of RNA polymerase II transcription subunit 17 › Mediator of RNA polymerase II transcription subunit 17 › Mediator of RNA polymerase II transcription subunit 17 | 0.61 | 54.0 | 3.43e-01 | 100.0% | 23.9% |
| 3508062 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.61 | 50.0 | 4.10e-01 | 88.6% | 81.4% |
| 3290823 | 809.1.1.0 ↗ | a+b two layers › BLIP-like › beta-lactamase-inhibitor protein, BLIP › beta-lactamase-inhibitor protein, BLIP | 0.61 | 41.0 | 4.25e-01 | 97.5% | 72.0% |
| 4480947 | 3016.1.1.1 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_1_2 | 0.61 | 56.0 | 4.52e-01 | 98.7% | 64.3% |
| 3287382 | 211.1.1.11 ↗ | a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase_6 | 0.61 | 37.0 | 4.02e-01 | 73.4% | 73.8% |
| 5006738 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.60 | 55.0 | 4.44e-01 | 100.0% | 62.8% |
| 5060537 | 7577.1.1.1 ↗ | a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_1_2 | 0.60 | 55.0 | 3.44e-01 | 100.0% | 22.5% |
| 4421566 | 3016.1.1.1 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_1_2 | 0.60 | 54.0 | 4.57e-01 | 98.7% | 72.8% |
| 4239781 | 3006.1.1.6 ↗ | a+b two layers › Sm-Like archaeal protein Smap3, C-terminal domain › Sm-Like archaeal protein Smap3, C-terminal domain › Sm-Like archaeal protein Smap3, C-terminal domain › CPSF73-100_C | 0.59 | 44.0 | 4.61e-01 | 79.7% | 95.7% |
| 3696140 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.59 | 53.0 | 4.22e-01 | 97.5% | 72.7% |
| 4857490 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.59 | 53.0 | 4.79e-01 | 97.5% | 83.7% |
| 3938950 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.59 | 52.0 | 4.20e-01 | 97.5% | 58.7% |
| 4124822 | 3016.1.1.1 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_1_2 | 0.59 | 54.0 | 4.41e-01 | 100.0% | 65.0% |
| 4936329 | 3016.1.1.1 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_1_2 | 0.59 | 53.0 | 4.48e-01 | 100.0% | 70.0% |
| 1839913 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.58 | 51.0 | 4.85e-01 | 97.5% | 90.5% |
| 1294511 | 7579.1.1.36 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_3 | 0.58 | 51.0 | 3.41e-01 | 100.0% | 81.0% |
| 4971751 | 331.1.1.0 ↗ | a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like | 0.58 | 44.0 | 3.86e-01 | 82.3% | 71.7% |
| 3831584 | 3016.1.1.1 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_1_2 | 0.58 | 51.0 | 4.22e-01 | 97.5% | 75.0% |
| 5026439 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.58 | 52.0 | 4.96e-01 | 98.7% | 94.4% |
| 1033396 | 243.4.1.1 ↗ | a+b two layers › Cystatin-like › DsbC/DsbG N-terminal domain-like › DsbC/DsbG N-terminal domain-like › DsbC_N | 0.58 | 38.0 | 3.88e-01 | 100.0% | 70.7% |
| 3257727 | 216.1.1.0 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like | 0.57 | 50.0 | 4.31e-01 | 100.0% | 65.4% |
| 5014721 | 331.1.1.0 ↗ | a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like | 0.57 | 48.0 | 4.46e-01 | 88.6% | 73.7% |
| 3360656 | 331.4.1.2 ↗ | a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 › NAF | 0.57 | 48.0 | 4.07e-01 | 92.4% | 61.7% |
| 3319246 | 2007.5.1.17 ↗ | a/b three-layered sandwiches › Flavodoxin-like › SGNH hydrolase › SGNH hydrolase › PC-Esterase | 0.56 | 47.0 | 3.44e-01 | 98.7% | 87.5% |
| 1277666 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.56 | 49.0 | 4.40e-01 | 100.0% | 85.1% |
| 2161921 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.56 | 46.0 | 4.56e-01 | 92.4% | 91.8% |
| 3781848 | 247.1.1.38 ↗ | a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › CPSF73-100_C | 0.55 | 43.0 | 4.57e-01 | 87.3% | 98.6% |
| 3627280 | 331.23.1.0 ↗ | a+b two layers › TBP-like › Integrator IntS9/IntS11 C-terminal domain › Integrator IntS9/IntS11 C-terminal domain | 0.54 | 43.0 | 4.39e-01 | 84.8% | 94.7% |
| 3649742 | 2004.1.1.17 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Myosin_head | 0.53 | 46.0 | 2.69e-01 | 93.7% | 14.5% |
| 3717071 | 7579.1.1.0 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases | 0.53 | 45.0 | 3.01e-01 | 97.5% | 86.8% |
| 4952031 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.51 | 36.0 | 3.34e-01 | 73.4% | 82.0% |
| 4177859 | 2.1.1.84 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Prot_ATP_ID_OB_N | 0.51 | 31.0 | 3.40e-01 | 77.2% | 75.4% |
D2
high
residues 114-228
Domain cluster:
representative
CATH (33)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1rp3A01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.81 | 53.0 | 6.11e-01 | 72.2% | 90.6% |
| 3a06B03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.74 | 49.0 | 5.46e-01 | 71.3% | 87.5% |
| 4zqeA03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.71 | 49.0 | 5.34e-01 | 70.4% | 86.5% |
| 2khmA01 | 1.10.10.1350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain | 0.70 | 41.0 | 4.25e-01 | 94.8% | 62.0% |
| 2xokP00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.68 | 36.0 | 4.35e-01 | 93.0% | 79.7% |
| 1aj3A00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 35.0 | 3.80e-01 | 93.0% | 58.2% |
| 2odmA00 | 1.10.287.750 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like | 0.67 | 31.0 | 3.69e-01 | 87.8% | 63.3% |
| 2d9dA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.64 | 31.0 | 3.50e-01 | 92.2% | 58.4% |
| 2v5cA03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.63 | 37.0 | 3.54e-01 | 100.0% | 50.8% |
| 2nq2A00 | 1.10.3470.10 | Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC | 0.60 | 45.0 | 3.34e-01 | 79.1% | 98.1% |
| 6todA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 43.0 | 3.24e-01 | 76.5% | 41.6% |
| 1e3pA02 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.59 | 39.0 | 4.44e-01 | 93.9% | 92.8% |
| 3qf7A02 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.58 | 28.0 | 3.73e-01 | 97.4% | 85.7% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.57 | 31.0 | 3.55e-01 | 100.0% | 70.6% |
| 5nl6A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 31.0 | 3.25e-01 | 92.2% | 57.4% |
| 3l9vC00 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.55 | 41.0 | 3.52e-01 | 77.4% | 98.9% |
| 7kypB01 | 1.10.3470.10 | Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC | 0.55 | 46.0 | 3.51e-01 | 91.3% | 99.3% |
| 3vr4B04 | 1.10.1140.10 | Mainly Alpha › Orthogonal Bundle › Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain; Chain D, domain3 › Bovine Mitochondrial F1-atpase; Atp Synthase Beta Chain; Chain D, domain 3 | 0.55 | 38.0 | 3.55e-01 | 72.2% | 68.9% |
| 2w02B06 | 1.10.340.60 | Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › AcsD, palm domain, helix bundle | 0.55 | 38.0 | 4.21e-01 | 99.1% | 89.1% |
| 7yu4A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.54 | 41.0 | 3.24e-01 | 80.9% | 44.0% |
| 1g2nA00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.54 | 47.0 | 3.69e-01 | 94.8% | 50.0% |
| 6rv2A00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.53 | 40.0 | 3.17e-01 | 80.0% | 70.9% |
| 8sbeA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.53 | 45.0 | 3.81e-01 | 93.0% | 59.7% |
| 1uddA00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.53 | 44.0 | 3.57e-01 | 89.6% | 84.2% |
| 3d85C00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.53 | 39.0 | 3.78e-01 | 90.4% | 66.9% |
| 3o7pA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.53 | 47.0 | 3.85e-01 | 100.0% | 92.7% |
| 7xpzA01 | 1.20.1720.10 | Mainly Alpha › Up-down Bundle › Multidrug resistance protein D › Multidrug resistance protein D | 0.53 | 44.0 | 3.10e-01 | 93.0% | 30.5% |
| 6fmhB01 | 1.10.3160.10 | Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 | 0.52 | 44.0 | 3.88e-01 | 93.0% | 61.6% |
| 8sbeA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.52 | 44.0 | 3.81e-01 | 93.0% | 68.4% |
| 1eqfA02 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.52 | 42.0 | 4.14e-01 | 88.7% | 80.0% |
| 2wyhB04 | 1.20.1270.50 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain | 0.52 | 39.0 | 4.14e-01 | 78.3% | 97.0% |
| 3ousA00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.50 | 34.0 | 3.83e-01 | 93.0% | 95.1% |
| 1jt6A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.50 | 35.0 | 3.32e-01 | 71.3% | 61.3% |
ECOD (34)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3925268 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.71 | 34.0 | 3.71e-01 | 91.3% | 53.0% |
| 3872783 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.68 | 33.0 | 3.51e-01 | 92.2% | 52.0% |
| 5040450 | 3281.1.1.1 ↗ | alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related › Proton_antipo_M | 0.66 | 56.0 | 3.72e-01 | 92.2% | 27.4% |
| 3659207 | 142.1.1.22 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › SCAF11-like_C | 0.64 | 48.0 | 5.25e-01 | 79.1% | 100.0% |
| 4236831 | 604.6.1.50 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › DUF2524 | 0.59 | 30.0 | 3.61e-01 | 90.4% | 71.2% |
| 3609115 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.59 | 52.0 | 4.24e-01 | 95.7% | 92.2% |
| 3314530 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.58 | 29.0 | 3.08e-01 | 93.0% | 51.0% |
| 4624818 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.58 | 35.0 | 3.98e-01 | 87.0% | 77.8% |
| 3206663 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.58 | 49.0 | 3.87e-01 | 93.0% | 61.7% |
| 5050149 | 601.7.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN | 0.57 | 34.0 | 3.28e-01 | 100.0% | 51.5% |
| 3468425 | 180.1.1.1 ↗ | alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › PAP2 | 0.55 | 41.0 | 3.50e-01 | 78.3% | 89.5% |
| 4332714 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.55 | 47.0 | 3.91e-01 | 93.0% | 59.0% |
| 4982547 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.55 | 50.0 | 4.17e-01 | 100.0% | 91.0% |
| 3402483 | 5050.1.1.5 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Folate_carrier | 0.55 | 47.0 | 3.83e-01 | 93.0% | 56.3% |
| 3459019 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.55 | 39.0 | 3.91e-01 | 89.6% | 72.2% |
| 3870846 | 3745.1.1.1 ↗ | alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Na_Ca_ex | 0.55 | 48.0 | 3.52e-01 | 96.5% | 59.1% |
| 3721496 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.55 | 49.0 | 3.84e-01 | 100.0% | 86.8% |
| 3858331 | 601.1.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › TLN1-like_RS | 0.54 | 39.0 | 3.52e-01 | 73.9% | 58.7% |
| 3285842 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 46.0 | 3.90e-01 | 93.0% | 61.6% |
| 3977166 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.53 | 47.0 | 3.83e-01 | 99.1% | 91.6% |
| 3618142 | 3939.1.1.0 ↗ | alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain | 0.53 | 36.0 | 3.93e-01 | 71.3% | 85.3% |
| 3584463 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.53 | 39.0 | 3.13e-01 | 93.0% | 40.0% |
| 5060738 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 46.0 | 3.93e-01 | 98.3% | 97.4% |
| 4952830 | 4070.1.1.0 ↗ | alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like | 0.52 | 36.0 | 3.13e-01 | 70.4% | 78.9% |
| 5002597 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 44.0 | 3.82e-01 | 93.0% | 60.0% |
| 4096052 | 4044.1.1.1 ↗ | alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Prismane | 0.52 | 40.0 | 3.68e-01 | 80.0% | 63.4% |
| 3970030 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 46.0 | 3.85e-01 | 98.3% | 88.0% |
| 3517672 | 601.1.1.7 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B | 0.52 | 37.0 | 3.40e-01 | 73.9% | 63.3% |
| 3733754 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.51 | 46.0 | 3.82e-01 | 100.0% | 85.7% |
| 3920189 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.51 | 44.0 | 3.64e-01 | 92.2% | 59.0% |
| 3785424 | 5069.1.3.6 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › MCP1_TM | 0.51 | 42.0 | 3.33e-01 | 92.2% | 86.7% |
| 5026679 | 7014.1.1.1 ↗ | alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA | 0.51 | 41.0 | 3.20e-01 | 87.0% | 86.0% |
| 3840045 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.50 | 33.0 | 3.93e-01 | 88.7% | 97.5% |
| 4962406 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.50 | 44.0 | 3.76e-01 | 99.1% | 91.4% |
D3
high
residues 264-317
D4
high
residues 331-432
Domain cluster:
representative
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3to7A03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.64 | 36.0 | 4.04e-01 | 96.1% | 70.4% |
| 6oinA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.58 | 31.0 | 3.74e-01 | 84.3% | 77.6% |
| 4iluA02 | 1.20.58.1290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain | 0.56 | 36.0 | 3.51e-01 | 83.3% | 58.6% |
| 4xriA00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.55 | 43.0 | 2.58e-01 | 87.3% | 10.2% |
| 4ldsA00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.53 | 43.0 | 2.89e-01 | 88.2% | 34.4% |
| 5l0wB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.52 | 38.0 | 3.40e-01 | 74.5% | 90.6% |
| 4mhcA01 | 1.20.58.1780 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 41.0 | 3.17e-01 | 86.3% | 56.7% |
| 3ibvB00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.52 | 41.0 | 2.43e-01 | 86.3% | 10.6% |
| 3efoB01 | 1.20.120.730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Sec23/Sec24 helical domain | 0.52 | 44.0 | 3.90e-01 | 95.1% | 94.7% |
| 1np7A02 | 1.25.40.80 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.51 | 34.0 | 3.24e-01 | 70.6% | 56.3% |
| 1hzfA00 | 1.50.10.20 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.51 | 38.0 | 2.75e-01 | 100.0% | 26.5% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4403239 | 101.35.1.4 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH3 | 0.62 | 35.0 | 4.44e-01 | 79.4% | 96.7% |
| 3899342 | 109.25.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A › GAIN | 0.58 | 43.0 | 4.00e-01 | 86.3% | 63.2% |
| 3694928 | 3924.1.1.0 ↗ | alpha complex topology › Sterol uptake control protein 2 › Sterol uptake control protein 2 › Sterol uptake control protein 2 | 0.54 | 48.0 | 3.88e-01 | 98.0% | 74.4% |
| 1117802 | 109.26.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nucleoporin_C | 0.53 | 42.0 | 3.24e-01 | 85.3% | 61.8% |
D5
high
residues 476-538
Domain cluster:
representative
CATH (26)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3goxA02 | 3.30.60.130 | Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › | 0.75 | 48.0 | 5.19e-01 | 73.0% | 75.9% |
| 5mmjv00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.67 | 41.0 | 3.86e-01 | 79.4% | 48.8% |
| 2j8aA01 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.67 | 42.0 | 3.82e-01 | 84.1% | 46.0% |
| 1pu1A00 | 3.30.300.100 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › MTH677-like | 0.66 | 51.0 | 4.50e-01 | 93.7% | 58.2% |
| 3laaA00 | 2.150.10.10 | Mainly Beta › 2 Solenoid › Alkaline Protease, subunit P, domain 1 › Serralysin-like metalloprotease, C-terminal | 0.62 | 37.0 | 2.70e-01 | 90.5% | 21.9% |
| 1x4eA00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.62 | 40.0 | 3.62e-01 | 90.5% | 48.2% |
| 3goxA03 | 3.40.1800.10 | Alpha Beta › 3-Layer(aba) Sandwich › His-Me finger endonuclease fold › His-Me finger endonucleases | 0.58 | 45.0 | 4.17e-01 | 90.5% | 66.7% |
| 2oarB00 | 1.10.1200.120 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Large-conductance mechanosensitive channel, MscL; domain 1 | 0.58 | 41.0 | 3.37e-01 | 76.2% | 57.6% |
| 2qgpA00 | 1.10.30.50 | Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › | 0.57 | 47.0 | 4.39e-01 | 100.0% | 74.7% |
| 4wiwA02 | 3.10.50.10 | Alpha Beta › Roll › Chitinase A; domain 3 › | 0.55 | 32.0 | 3.14e-01 | 71.4% | 50.7% |
| 3kbgA02 | 2.40.50.740 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Ribosomal protein S4, central domain | 0.55 | 31.0 | 3.28e-01 | 87.3% | 60.4% |
| 1zbdB00 | 3.30.40.10 | Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) | 0.55 | 40.0 | 3.18e-01 | 76.2% | 66.7% |
| 4iufA00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.55 | 34.0 | 3.30e-01 | 85.7% | 51.9% |
| 5zwnQ01 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.55 | 35.0 | 3.29e-01 | 88.9% | 51.2% |
| 2zgyA02 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.54 | 40.0 | 3.12e-01 | 100.0% | 35.7% |
| 6kghA02 | 3.30.450.330 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › | 0.54 | 39.0 | 2.92e-01 | 76.2% | 90.9% |
| 1p97A00 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.53 | 37.0 | 3.16e-01 | 76.2% | 57.0% |
| 1zhhB01 | 3.30.450.220 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › LuxQ periplasmic domain, N-terminal subdomain | 0.53 | 38.0 | 2.96e-01 | 79.4% | 96.8% |
| 6x4tA02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.53 | 34.0 | 3.17e-01 | 85.7% | 49.4% |
| 4zasA02 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.53 | 42.0 | 3.49e-01 | 90.5% | 96.6% |
| 5uzgA00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.53 | 43.0 | 3.83e-01 | 90.5% | 78.9% |
| 5gj7A02 | 2.40.110.10 | Mainly Beta › Beta Barrel › Butyryl-CoA Dehydrogenase, subunit A; domain 2 › Butyryl-CoA Dehydrogenase, subunit A, domain 2 | 0.51 | 37.0 | 3.33e-01 | 77.8% | 57.4% |
| 4kc9A02 | 1.20.120.1750 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.51 | 44.0 | 3.08e-01 | 100.0% | 47.5% |
| 2bopA00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.51 | 35.0 | 3.28e-01 | 77.8% | 55.3% |
| 5vbfA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.50 | 41.0 | 2.76e-01 | 96.8% | 57.6% |
| 3ndaA02 | 2.30.39.10 | Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 | 0.50 | 39.0 | 3.15e-01 | 87.3% | 99.2% |
ECOD (25)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3385224 | 708.1.2.0 ↗ | beta complex topology › ETN0001 domain-like › ETN0001 domain-like › Mss4-like | 0.67 | 36.0 | 2.91e-01 | 74.6% | 26.9% |
| 3234625 | 5067.1.1.3 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Patched | 0.61 | 53.0 | 2.98e-01 | 98.4% | 18.0% |
| 3286658 | 378.1.1.0 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases | 0.59 | 49.0 | 4.00e-01 | 98.4% | 51.5% |
| 3233208 | 5067.1.1.3 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Patched | 0.58 | 49.0 | 2.76e-01 | 98.4% | 21.9% |
| 3804865 | 207.1.1.55 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_1,LRR_8 | 0.58 | 42.0 | 2.60e-01 | 79.4% | 29.2% |
| 3295810 | 386.1.1.249 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › PF25908 | 0.57 | 43.0 | 3.93e-01 | 90.5% | 61.2% |
| 3799089 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.57 | 44.0 | 2.57e-01 | 84.1% | 16.6% |
| 3933064 | 3382.1.1.1 ↗ | alpha arrays › Protein Wnt-8 › Protein Wnt-8 › Protein Wnt-8 › wnt | 0.57 | 47.0 | 3.15e-01 | 100.0% | 67.1% |
| 3914774 | 5067.1.1.3 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Patched | 0.56 | 49.0 | 2.74e-01 | 100.0% | 58.5% |
| 3931962 | 207.1.1.0 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats | 0.56 | 45.0 | 3.01e-01 | 95.2% | 36.3% |
| 3794104 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.55 | 43.0 | 3.06e-01 | 90.5% | 47.6% |
| 3690425 | 2003.1.2.15 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_3 | 0.55 | 43.0 | 2.84e-01 | 92.1% | 34.1% |
| 3483119 | 389.1.1.0 ↗ | few secondary structure elements › EGF-like › EGF-related › EGF/Laminin | 0.55 | 27.0 | 3.16e-01 | 76.2% | 65.0% |
| 3991465 | 304.28.1.9 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › Patched | 0.54 | 47.0 | 2.67e-01 | 100.0% | 49.0% |
| 4375816 | 314.1.1.12 ↗ | a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › LplA-B_cat | 0.54 | 46.0 | 3.15e-01 | 98.4% | 34.5% |
| 4029394 | 4964.1.1.2 ↗ | alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › RNA_pol | 0.54 | 41.0 | 2.92e-01 | 82.5% | 57.4% |
| 3581477 | 386.1.1.0 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers | 0.53 | 37.0 | 4.32e-01 | 73.0% | 100.0% |
| 3939681 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.53 | 40.0 | 2.54e-01 | 81.0% | 33.6% |
| 4941657 | 377.1.1.88 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › HNH | 0.53 | 40.0 | 3.86e-01 | 85.7% | 74.7% |
| 4888607 | 2003.1.2.113 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Smoa_sbd | 0.53 | 40.0 | 2.66e-01 | 82.5% | 84.0% |
| 5019258 | 378.1.1.2 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH | 0.53 | 42.0 | 3.98e-01 | 93.7% | 77.5% |
| 3698104 | 11.1.4.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like | 0.52 | 45.0 | 3.85e-01 | 98.4% | 99.0% |
| 3788784 | 101.1.21.0 ↗ | alpha arrays › HTH › HTH › HTH in T7 RNA polymerase | 0.51 | 46.0 | 3.17e-01 | 100.0% | 81.9% |
| 5049527 | 376.1.3.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger | 0.51 | 34.0 | 3.52e-01 | 71.4% | 73.3% |
| 3236544 | 3382.1.1.1 ↗ | alpha arrays › Protein Wnt-8 › Protein Wnt-8 › Protein Wnt-8 › wnt | 0.51 | 43.0 | 2.84e-01 | 98.4% | 66.1% |