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OR820514.1__WRQ05383.1__X__00005

Bact-Vir

OR820514.1__WRQ05383.1__X__00005

Identity

Accession:
OR820514 ↗
Kingdom:
phage

Quality

90.1 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 97-197
PDB
Domain cluster: representative
CATH (57)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1t72A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.80 69.0 6.54e-01 91.1% 86.3%
1vcsA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.78 69.0 6.91e-01 94.1% 92.2%
1lvfB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 68.0 6.74e-01 92.1% 100.0%
2oduA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 67.0 6.59e-01 90.1% 95.2%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 56.0 5.89e-01 76.2% 94.6%
5u56A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.76 61.0 5.89e-01 84.2% 81.2%
2yjkC00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.75 58.0 5.02e-01 82.2% 89.8%
1u5pA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 63.0 6.21e-01 91.1% 96.3%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.75 53.0 6.03e-01 86.1% 100.0%
6xkyA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.74 65.0 5.25e-01 94.1% 59.4%
5z7qA00 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.74 65.0 5.35e-01 94.1% 65.9%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.74 65.0 5.93e-01 94.1% 81.5%
1cunA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 62.0 6.22e-01 90.1% 99.0%
6h2dS01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.74 64.0 4.93e-01 94.1% 86.5%
1ugoA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.73 59.0 5.96e-01 94.1% 86.9%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.73 59.0 5.61e-01 87.1% 79.7%
1xzpA02 1.20.120.430 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 0.73 61.0 5.19e-01 92.1% 69.9%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.72 64.0 6.13e-01 94.1% 85.8%
2gscC00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.72 56.0 5.48e-01 89.1% 75.5%
1quuA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 59.0 5.51e-01 90.1% 82.5%
7p3rA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.70 60.0 4.21e-01 94.1% 85.8%
3pjaJ01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.70 57.0 5.23e-01 92.1% 67.2%
1w99A01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.70 59.0 4.90e-01 91.1% 94.2%
4aifA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.70 52.0 4.52e-01 90.1% 53.5%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.69 58.0 5.57e-01 89.1% 78.1%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.69 55.0 5.79e-01 84.2% 92.3%
2pftA00 1.20.1280.170 Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 0.69 56.0 3.54e-01 87.1% 32.9%
4nx9A01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.69 60.0 5.17e-01 94.1% 68.4%
2rkkA01 1.25.40.270 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 0.68 56.0 4.84e-01 94.1% 57.1%
7zm7601 1.20.120.1200 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ 0.68 44.0 3.60e-01 79.2% 39.5%
3kavA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.68 50.0 5.06e-01 86.1% 77.5%
1nigA00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.67 58.0 5.07e-01 92.1% 98.6%
2g2dA00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.66 55.0 4.69e-01 89.1% 93.8%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 57.0 4.99e-01 96.0% 64.3%
5j1hA01 1.20.58.1060 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 57.0 4.69e-01 96.0% 80.8%
2b1eA02 1.20.1310.30 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › 0.65 53.0 4.66e-01 89.1% 98.0%
3bt5A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.65 51.0 4.53e-01 86.1% 96.0%
2hujA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.64 55.0 5.16e-01 95.0% 80.8%
5cy5B00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.64 52.0 4.61e-01 88.1% 96.6%
7smtA02 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.63 55.0 4.57e-01 94.1% 95.4%
4g12A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.63 50.0 4.44e-01 86.1% 93.3%
4ackB00 1.25.40.590 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type IV / VI secretion system, DotU 0.63 52.0 4.50e-01 94.1% 58.2%
5dlqB01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.63 52.0 3.42e-01 90.1% 27.7%
4nwpD00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.63 51.0 4.52e-01 89.1% 95.3%
2z16B01 1.20.91.10 Mainly Alpha › Up-down Bundle › Influenza Virus Matrix Protein; Chain A, domain 1 › Influenza matrix M1, N-terminal subdomain 1 0.62 34.0 3.80e-01 81.2% 67.9%
8ek4A01 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.61 52.0 4.80e-01 94.1% 91.7%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.61 52.0 4.99e-01 94.1% 96.6%
2vj4A01 1.10.10.2060 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.61 38.0 3.98e-01 84.2% 68.9%
4hkaA01 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 52.0 3.78e-01 100.0% 90.5%
3vprA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 46.0 4.17e-01 87.1% 95.2%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.58 47.0 4.67e-01 89.1% 93.6%
3dcfA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 46.0 4.10e-01 85.1% 93.0%
2fonA04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.55 42.0 3.87e-01 86.1% 63.6%
1e8yA03 1.25.40.70 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Phosphatidylinositol 3-kinase, accessory domain (PIK) 0.54 35.0 2.90e-01 85.1% 35.5%
1xwjA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.54 48.0 4.41e-01 98.0% 80.8%
4hehA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.53 38.0 4.12e-01 81.2% 90.4%
4a64A01 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.51 44.0 4.14e-01 100.0% 92.4%
ECOD (80)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3837777 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.85 68.0 6.71e-01 83.2% 90.5%
3706209 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.83 70.0 6.05e-01 87.1% 64.8%
3282593 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.82 73.0 5.35e-01 94.1% 91.3%
3260973 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.81 69.0 6.75e-01 91.1% 90.9%
4024537 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.79 67.0 5.24e-01 89.1% 90.0%
3605710 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.79 57.0 6.54e-01 86.1% 100.0%
3502594 603.1.1.98 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE, Syntaxin_2 0.79 67.0 5.12e-01 90.1% 49.5%
None 0.79 67.0 5.07e-01 90.1% 79.6%
3743875 109.4.1.359 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo70_C 0.79 62.0 3.81e-01 90.1% 14.9%
3318923 603.1.1.124 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE, V-SNARE_C 0.79 68.0 5.82e-01 92.1% 63.2%
3260458 603.1.1.17 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.78 67.0 4.97e-01 91.1% 72.5%
3927597 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.78 66.0 6.24e-01 90.1% 92.5%
3917600 604.1.1.6 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_4 0.78 68.0 6.35e-01 91.1% 84.2%
3820110 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.78 67.0 5.94e-01 91.1% 80.0%
3849992 603.1.1.3 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.78 66.0 6.69e-01 90.1% 93.0%
3516162 603.1.1.23 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Sec20 0.78 70.0 5.77e-01 95.0% 74.1%
3870690 109.4.1.1647 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF28330 0.78 56.0 5.23e-01 81.2% 60.8%
3800819 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.77 63.0 4.44e-01 88.1% 77.7%
3262164 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.77 68.0 4.99e-01 96.0% 81.9%
3870558 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.77 65.0 6.13e-01 91.1% 93.3%
3244235 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.76 62.0 6.24e-01 86.1% 88.0%
3796191 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.76 64.0 6.20e-01 90.1% 89.1%
3639947 603.1.1.1 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin 0.76 67.0 5.33e-01 93.1% 95.7%
3478117 603.1.1.17 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.76 64.0 5.13e-01 90.1% 54.2%
5075236 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.75 65.0 6.06e-01 90.1% 85.0%
3815122 604.12.1.68 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › DUF6857 0.75 64.0 5.19e-01 91.1% 50.6%
3261432 603.1.1.17 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.75 67.0 5.09e-01 94.1% 74.4%
3389546 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.75 56.0 6.23e-01 91.1% 98.8%
3405261 604.22.1.1 alpha bundles › Spectrin repeat-like › tubulin binding cofactor C N-terminal domain › tubulin binding cofactor C N-terminal domain › TBCC_N 0.75 61.0 5.77e-01 90.1% 72.5%
3212207 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.75 64.0 5.78e-01 91.1% 77.0%
3215426 192.29.1.172 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF29678 0.75 65.0 5.97e-01 94.1% 79.2%
3224518 5001.1.1.63 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srab 0.75 61.0 4.27e-01 88.1% 73.4%
5014336 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.75 65.0 5.76e-01 95.0% 73.8%
4971843 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.75 60.0 6.41e-01 91.1% 96.6%
4023110 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.75 65.0 5.05e-01 96.0% 60.9%
3251611 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.74 66.0 5.05e-01 95.0% 79.1%
3828953 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.74 59.0 3.58e-01 83.2% 16.2%
3968878 603.2.1.0 alpha bundles › STAT-like › STAT › STAT 0.74 67.0 5.08e-01 97.0% 90.6%
3192001 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.74 63.0 5.60e-01 91.1% 73.6%
3495945 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.74 63.0 6.02e-01 93.1% 79.1%
4946407 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.74 64.0 4.04e-01 94.1% 29.0%
5074225 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.74 59.0 6.24e-01 86.1% 100.0%
4622749 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.74 61.0 6.10e-01 90.1% 95.2%
3212811 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.73 63.0 5.81e-01 95.0% 92.3%
3303368 109.4.1.37 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BRO1 0.72 66.0 4.40e-01 100.0% 39.5%
3320550 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.72 64.0 5.00e-01 97.0% 47.3%
3732353 109.4.1.128 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MIF4G_like_2 0.71 66.0 4.74e-01 100.0% 53.8%
3620474 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.71 56.0 5.93e-01 86.1% 92.2%
4200809 603.1.1.9 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › COG2p_C 0.71 59.0 5.05e-01 91.1% 56.2%
4996069 604.10.1.0 alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac 0.71 59.0 6.21e-01 91.1% 98.9%
3255910 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 66.0 4.28e-01 99.0% 37.8%
3230738 5001.1.1.63 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srab 0.71 57.0 4.00e-01 87.1% 71.4%
3334062 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.70 50.0 5.45e-01 86.1% 90.4%
4836886 5057.1.1.1 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb 0.70 54.0 5.79e-01 84.2% 94.3%
4969464 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.69 55.0 5.81e-01 90.1% 96.7%
4011740 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.69 55.0 5.61e-01 87.1% 89.0%
3592945 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.69 56.0 5.78e-01 92.1% 92.6%
3688535 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.68 58.0 3.82e-01 90.1% 41.5%
3233698 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.68 56.0 5.20e-01 87.1% 93.6%
3429544 109.52.1.1 alpha superhelices › Repetitive alpha hairpins › FRIGIDA flowering-time regulator › FRIGIDA flowering-time regulator › Frigida 0.67 59.0 4.26e-01 96.0% 36.8%
3304829 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.67 59.0 4.93e-01 94.1% 60.1%
3239549 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.67 55.0 3.94e-01 88.1% 49.8%
3542709 3861.1.1.1 alpha bundles › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › TspO_MBR 0.66 52.0 4.37e-01 88.1% 50.9%
3215718 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.66 49.0 5.45e-01 77.2% 96.2%
3583915 192.29.1.51 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › TMEM138 0.66 58.0 5.17e-01 95.0% 85.7%
4972684 150.3.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine 0.66 53.0 5.17e-01 94.1% 80.0%
3514794 5057.1.1.1 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb 0.66 55.0 5.18e-01 91.1% 75.8%
5057381 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.65 51.0 5.46e-01 93.1% 100.0%
3607237 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 58.0 4.78e-01 99.0% 80.6%
4315581 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 56.0 4.01e-01 99.0% 67.2%
5010324 150.2.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Cobalamin adenosyltransferase › Cobalamin adenosyltransferase › Cob_adeno_trans 0.63 54.0 4.56e-01 94.1% 94.1%
4980072 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.63 56.0 4.75e-01 95.0% 96.8%
4025307 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.63 54.0 4.55e-01 93.1% 76.4%
3213286 5001.1.1.63 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srab 0.63 55.0 4.00e-01 98.0% 79.3%
3476494 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.61 52.0 4.69e-01 94.1% 86.4%
4026931 109.4.1.1413 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF28415 0.61 51.0 3.61e-01 92.1% 39.0%
3220993 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.60 50.0 4.52e-01 94.1% 84.0%
3917311 5057.1.1.1 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb 0.60 52.0 4.71e-01 97.0% 85.6%
3235528 5057.1.1.1 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb 0.59 50.0 4.50e-01 94.1% 83.4%
3704640 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 51.0 3.96e-01 100.0% 58.7%
D2 high residues 208-288
PDB
Domain cluster: representative
CATH (55)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3pwfA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.92 63.0 5.18e-01 70.4% 50.4%
2v6yA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.82 71.0 7.34e-01 100.0% 98.7%
3u8vA00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.82 62.0 6.19e-01 96.3% 77.1%
4j8dD00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.81 56.0 4.36e-01 95.1% 35.8%
1a17A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.80 56.0 4.36e-01 95.1% 36.5%
2jbwA01 1.20.1440.110 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase 0.80 66.0 6.03e-01 98.8% 68.9%
4yvoA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.79 58.0 5.02e-01 96.3% 52.1%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.79 68.0 6.98e-01 97.5% 97.4%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.78 67.0 6.97e-01 95.1% 100.0%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.76 68.0 6.47e-01 96.3% 92.5%
2yxhA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.76 56.0 4.93e-01 77.8% 54.9%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.76 69.0 5.57e-01 100.0% 54.4%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.76 67.0 6.19e-01 96.3% 90.2%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.75 67.0 6.13e-01 96.3% 92.2%
1yvwA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.74 54.0 5.17e-01 82.7% 66.3%
4g1tA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.74 54.0 4.65e-01 86.4% 50.4%
1e2aA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.74 65.0 6.02e-01 96.3% 89.2%
1vcsA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.74 63.0 5.89e-01 95.1% 87.3%
1cnt200 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.74 49.0 4.21e-01 71.6% 43.1%
1h6gA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.73 67.0 5.77e-01 100.0% 74.2%
3dyjA02 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.73 61.0 5.00e-01 92.6% 57.0%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.72 53.0 4.94e-01 97.5% 63.0%
3e6sA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.71 63.0 5.11e-01 100.0% 88.7%
3r2kA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.71 62.0 5.09e-01 100.0% 90.3%
3nbxX03 1.20.58.1510 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 57.0 5.36e-01 88.9% 84.2%
1nzeA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.70 60.0 5.45e-01 96.3% 71.4%
1ax8A00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.70 46.0 3.98e-01 75.3% 42.3%
4cmyA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.70 62.0 4.95e-01 100.0% 87.1%
1q0gA00 1.20.120.400 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase 0.69 59.0 5.18e-01 92.6% 73.5%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.69 60.0 5.72e-01 100.0% 96.9%
2qqyA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.68 58.0 4.93e-01 96.3% 97.1%
3anwA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 54.0 4.84e-01 85.2% 84.1%
3rh3A01 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.67 47.0 4.01e-01 72.8% 46.6%
1lkoA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.67 58.0 4.88e-01 100.0% 94.5%
2hsbA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.67 61.0 5.11e-01 95.1% 82.5%
1vq8V00 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 49.0 5.35e-01 80.2% 98.5%
3eslA02 1.25.40.930 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.67 49.0 4.30e-01 95.1% 52.9%
1wolA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.67 61.0 5.15e-01 95.1% 84.4%
1jgcA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.66 63.0 4.88e-01 100.0% 91.9%
4nwpD00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.66 58.0 4.82e-01 100.0% 94.0%
1yw0A00 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 59.0 4.18e-01 98.8% 67.1%
1o3uA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.66 58.0 4.93e-01 91.4% 84.2%
1s3qG00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.65 61.0 4.73e-01 98.8% 91.4%
3c18A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.65 60.0 5.20e-01 97.5% 72.0%
1vjxA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.65 56.0 4.69e-01 100.0% 95.3%
3ihuA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.64 54.0 4.50e-01 90.1% 77.7%
1bgfA00 1.10.532.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain 0.64 51.0 4.46e-01 86.4% 55.6%
1f6fA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.64 55.0 4.18e-01 92.6% 71.0%
4p9fA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.64 54.0 4.48e-01 93.8% 79.2%
8d7hD01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.63 55.0 4.29e-01 96.3% 74.6%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.62 50.0 5.10e-01 96.3% 93.7%
2q24A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.61 54.0 4.26e-01 100.0% 69.9%
3nkzA00 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.60 54.0 5.11e-01 100.0% 89.7%
2wwxB00 1.20.1260.70 Mainly Alpha › Up-down Bundle › Ferritin › 0.59 53.0 3.96e-01 100.0% 66.5%
2yx8A00 1.10.150.510 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Receptor activity modifying family 0.56 47.0 4.71e-01 92.6% 93.8%
ECOD (47)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5022800 150.1.1.3 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.93 64.0 5.40e-01 70.4% 56.7%
4957516 150.1.1.3 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.91 62.0 5.24e-01 70.4% 53.2%
5056592 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.86 66.0 4.13e-01 79.0% 28.9%
3614952 109.4.1.1287 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_6, TPR_8, TPR_16 0.83 74.0 4.28e-01 96.3% 11.5%
3598711 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.83 74.0 4.23e-01 96.3% 10.7%
3772724 109.4.1.1294 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, ANAPC3, TPR_8, TPR_12, TPR_16 0.83 74.0 4.44e-01 96.3% 15.7%
5062478 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.82 74.0 7.12e-01 100.0% 86.7%
3956529 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.82 74.0 5.43e-01 98.8% 70.7%
4957069 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.82 76.0 5.70e-01 100.0% 71.4%
4950659 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.82 76.0 5.56e-01 100.0% 78.0%
3387211 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.82 75.0 5.30e-01 98.8% 61.8%
4058399 109.4.1.37 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BRO1 0.80 74.0 4.71e-01 100.0% 23.8%
3589651 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.80 72.0 5.56e-01 97.5% 80.6%
4931875 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.80 73.0 5.37e-01 98.8% 92.0%
5001194 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.80 74.0 5.45e-01 100.0% 71.8%
3629701 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.80 72.0 7.09e-01 100.0% 92.9%
5036828 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.80 71.0 5.40e-01 96.3% 73.3%
3665244 109.7.1.0 alpha superhelices › Repetitive alpha hairpins › Cytochrome c oxidase subunit E › Cytochrome c oxidase subunit E 0.80 59.0 4.62e-01 100.0% 40.0%
4104119 604.12.1.9 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › ATG1-like_MIT2 0.79 73.0 7.08e-01 100.0% 95.5%
4030597 603.1.1.3 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.79 72.0 6.86e-01 100.0% 91.6%
5002688 109.4.1.186 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ANAPC3 0.79 70.0 4.93e-01 98.8% 32.5%
3498656 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.78 68.0 6.61e-01 95.1% 98.9%
164631 109.12.1.1 alpha superhelices › Repetitive alpha hairpins › C-terminal domain of Ku80 › C-terminal domain of Ku80 › MAS20 0.78 56.0 6.16e-01 95.1% 90.9%
3833909 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.78 68.0 5.70e-01 96.3% 56.5%
3770783 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.78 69.0 6.43e-01 96.3% 85.0%
3395652 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.78 66.0 5.84e-01 92.6% 74.8%
162201 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.77 71.0 6.26e-01 100.0% 75.9%
3829890 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.77 67.0 5.61e-01 96.3% 56.1%
3341433 604.12.1.77 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › PMEI 0.76 63.0 6.03e-01 91.4% 83.2%
3627573 192.17.1.10 alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like › eIF-3c_N 0.73 66.0 5.87e-01 100.0% 77.4%
54382 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.73 66.0 5.68e-01 100.0% 74.2%
3245655 101.1.2.552 alpha arrays › HTH › HTH › winged helix domain › eIF-3c_N 0.72 65.0 5.70e-01 100.0% 75.0%
4535292 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.72 65.0 5.43e-01 100.0% 62.2%
2099726 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.70 59.0 5.37e-01 92.6% 72.5%
5011132 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.68 60.0 4.96e-01 91.4% 83.1%
5009844 601.7.1.3 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › PaREP1 0.68 62.0 4.75e-01 95.1% 76.9%
5012033 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.67 61.0 5.28e-01 93.8% 80.9%
4183373 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.67 61.0 5.11e-01 93.8% 83.2%
5038830 375.1.1.26 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2 0.67 60.0 5.51e-01 95.1% 84.0%
4996239 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.66 60.0 4.85e-01 95.1% 75.0%
3914266 150.3.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine 0.65 55.0 4.40e-01 92.6% 69.4%
4981470 150.1.1.3 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.65 57.0 4.62e-01 100.0% 87.3%
5077945 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.65 61.0 5.25e-01 100.0% 76.7%
5051415 150.1.1.3 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.64 61.0 4.65e-01 100.0% 90.9%
4953715 5054.1.1.6 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH 0.64 45.0 3.70e-01 74.1% 42.7%
4276755 3291.1.1.56 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Mgr1 0.62 46.0 3.95e-01 80.2% 51.1%
3829175 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.60 55.0 4.74e-01 96.3% 76.7%
D3 high residues 448-532
PDB
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4oj5B01 3.30.2020.50 Alpha Beta › 2-Layer Sandwich › NE0471 N-terminal domain-like › 0.60 37.0 3.80e-01 75.3% 64.6%
3n6rA03 3.30.700.30 Alpha Beta › 2-Layer Sandwich › Glycoprotein, Type 4 Pilin › 0.57 42.0 3.68e-01 80.0% 97.0%
2k4jA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 34.0 3.24e-01 100.0% 50.5%
1xteA00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.52 41.0 3.67e-01 83.5% 92.2%
1omoA01 3.30.1780.10 Alpha Beta › 2-Layer Sandwich › ornithine cyclodeaminase, domain 1 › ornithine cyclodeaminase, domain 1 0.50 44.0 3.70e-01 100.0% 72.5%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4569026 4041.1.1.1 a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 0.54 47.0 3.88e-01 97.6% 88.1%
None 0.52 40.0 2.97e-01 84.7% 40.0%
3921669 2003.1.5.146 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GuanidinoAc_N-MeTrfase 0.52 36.0 2.71e-01 72.9% 92.7%
D4 medium residues 1-52
PDB
Domain cluster: representative
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2amyA01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.68 48.0 3.55e-01 76.9% 55.8%
2zvfA02 3.10.310.40 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › 0.60 48.0 3.99e-01 96.2% 73.6%
1u02A01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.60 44.0 3.26e-01 82.7% 51.0%
3fzqB01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.60 42.0 3.06e-01 76.9% 47.8%
3ddjA01 3.10.580.10 Alpha Beta › Roll › CBS-domain › CBS-domain 0.59 43.0 3.30e-01 80.8% 54.4%
1wr8A01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.59 43.0 3.13e-01 78.8% 47.2%
1nrwA01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.57 40.0 3.00e-01 78.8% 50.0%
4gc1A01 2.90.10.10 Mainly Beta › Orthogonal Prism › Agglutinin, subunit A › Bulb-type lectin domain 0.57 49.0 3.94e-01 100.0% 81.7%
3mhsA01 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.56 41.0 3.23e-01 82.7% 74.8%
3g7sA01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.55 44.0 2.68e-01 96.2% 54.7%
3c5mA00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.55 40.0 2.44e-01 100.0% 11.2%
1o50A00 3.10.580.10 Alpha Beta › Roll › CBS-domain › CBS-domain 0.54 38.0 2.96e-01 80.8% 53.2%
3nyqA01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.54 41.0 2.58e-01 92.3% 22.2%
3m4xA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 44.0 2.84e-01 100.0% 92.2%
3hxlA05 3.30.360.90 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › 0.53 36.0 3.33e-01 71.2% 100.0%
1uoyA01 2.30.130.50 Mainly Beta › Roll › Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 › 0.52 37.0 3.61e-01 75.0% 73.7%
3c7xA00 2.110.10.10 Mainly Beta › 4 Propeller › Hemopexin › Hemopexin-like domain 0.52 40.0 2.83e-01 90.4% 95.4%
3fzvD02 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.51 42.0 3.41e-01 98.1% 45.9%
3lmlA01 3.10.450.690 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.51 39.0 3.23e-01 96.2% 92.6%
4i92A02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.50 37.0 2.54e-01 80.8% 32.6%
1z01A02 2.20.25.680 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.50 35.0 3.44e-01 78.8% 72.1%
ECOD (29)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2075059 2006.1.1.5 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › PMM 0.68 49.0 4.29e-01 78.8% 96.3%
5056573 2006.1.1.11 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase_3 0.63 46.0 3.03e-01 78.8% 33.8%
4222587 2006.1.1.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like 0.63 44.0 3.26e-01 76.9% 45.8%
4658845 2006.1.1.11 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase_3 0.61 43.0 2.90e-01 78.8% 33.2%
5024087 2006.1.1.11 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase_3 0.60 44.0 3.18e-01 78.8% 47.5%
1585469 2006.1.1.11 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase_3 0.60 42.0 3.72e-01 76.9% 92.6%
4930486 282.1.1.0 a+b duplicates or obligate multimers › CBS-domain › CBS-domain › CBS-domain 0.58 41.0 3.44e-01 78.8% 45.0%
4021531 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.58 41.0 3.37e-01 76.9% 42.9%
4933793 2006.1.1.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like 0.57 43.0 3.08e-01 84.6% 47.1%
3963939 2006.1.1.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like 0.57 42.0 3.03e-01 80.8% 56.2%
3954395 3097.1.1.0 a+b two layers › Ribosome-associated factor Y › Ribosome-associated factor Y › Ribosome-associated factor Y 0.56 40.0 3.98e-01 78.8% 87.3%
3987400 2006.1.1.37 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › S6PP+Hydrolase_3 0.56 43.0 2.74e-01 88.5% 34.2%
3670801 282.1.1.1 a+b duplicates or obligate multimers › CBS-domain › CBS-domain › CBS-domain › CBS 0.55 39.0 2.82e-01 80.8% 36.8%
3973075 7523.1.1.0 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II 0.54 44.0 3.55e-01 98.1% 45.7%
4995095 282.1.1.1 a+b duplicates or obligate multimers › CBS-domain › CBS-domain › CBS-domain › CBS 0.54 39.0 3.04e-01 80.8% 55.4%
4588602 3097.1.1.1 a+b two layers › Ribosome-associated factor Y › Ribosome-associated factor Y › Ribosome-associated factor Y › Ribosom_S30AE_C 0.54 39.0 3.99e-01 75.0% 92.0%
4995096 282.1.1.1 a+b duplicates or obligate multimers › CBS-domain › CBS-domain › CBS-domain › CBS 0.54 38.0 2.85e-01 80.8% 47.3%
4983376 282.1.1.1 a+b duplicates or obligate multimers › CBS-domain › CBS-domain › CBS-domain › CBS 0.54 38.0 2.98e-01 78.8% 44.6%
2075061 2006.1.1.11 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase_3 0.54 38.0 3.38e-01 78.8% 95.2%
3352811 5.3.1.0 beta duplicates or obligate multimers › beta-propeller-like › beta-Prism II › beta-Prism II 0.53 45.0 3.64e-01 100.0% 56.4%
3974477 7523.1.1.0 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II 0.52 43.0 3.49e-01 98.1% 46.7%
3961969 3097.1.1.1 a+b two layers › Ribosome-associated factor Y › Ribosome-associated factor Y › Ribosome-associated factor Y › Ribosom_S30AE_C 0.52 38.0 3.71e-01 78.8% 80.0%
4999131 282.1.1.1 a+b duplicates or obligate multimers › CBS-domain › CBS-domain › CBS-domain › CBS 0.52 40.0 3.11e-01 90.4% 38.3%
3290657 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.52 39.0 2.59e-01 86.5% 29.8%
4985783 282.1.1.1 a+b duplicates or obligate multimers › CBS-domain › CBS-domain › CBS-domain › CBS 0.51 37.0 2.99e-01 80.8% 40.0%
3586838 2006.1.1.37 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › S6PP+Hydrolase_3 0.51 43.0 2.80e-01 100.0% 68.6%
3289024 3097.1.1.1 a+b two layers › Ribosome-associated factor Y › Ribosome-associated factor Y › Ribosome-associated factor Y › Ribosom_S30AE_C 0.50 38.0 3.34e-01 94.2% 69.5%
5004756 282.1.1.1 a+b duplicates or obligate multimers › CBS-domain › CBS-domain › CBS-domain › CBS 0.50 36.0 2.88e-01 80.8% 50.8%
3211135 282.1.1.1 a+b duplicates or obligate multimers › CBS-domain › CBS-domain › CBS-domain › CBS 0.50 41.0 3.03e-01 98.1% 32.9%
D5 medium residues 295-350
PDB
Domain cluster: representative
CATH (20)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3nymA00 6.10.290.10 Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.80 55.0 4.16e-01 73.2% 32.3%
3oxfA05 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.79 67.0 6.08e-01 100.0% 70.7%
2v6yA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.79 70.0 6.35e-01 100.0% 82.7%
4jhrB00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.78 63.0 4.00e-01 100.0% 17.6%
2xgsB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.78 59.0 5.47e-01 96.4% 64.4%
2zueA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.77 64.0 5.06e-01 94.6% 59.7%
2ra1A03 1.20.58.770 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 65.0 6.25e-01 100.0% 90.5%
2wviA00 1.25.40.430 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.72 60.0 4.37e-01 100.0% 33.8%
3kfwX03 1.20.58.1460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 61.0 5.63e-01 100.0% 78.9%
2i0mA02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.71 60.0 5.08e-01 100.0% 79.2%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.71 59.0 4.90e-01 100.0% 52.0%
1wkbA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.71 63.0 4.91e-01 100.0% 57.0%
2jx0A00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.69 59.0 4.60e-01 100.0% 51.1%
3crmA02 1.10.287.890 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Crystal structure of tRNA isopentenylpyrophosphate transferase (bh2366) domain 0.64 43.0 3.87e-01 71.4% 76.2%
2hjmA01 1.20.120.460 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › protein pf1176 like 0.64 43.0 3.81e-01 71.4% 46.5%
3fnrA01 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.63 51.0 3.99e-01 100.0% 49.7%
2xubA05 6.10.140.1450 Special › Helix non-globular › Helix Hairpins › 0.58 41.0 3.60e-01 78.6% 45.8%
3pubA01 1.10.10.2400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Lepidopteran low molecular weight (30 kD) lipoprotein, N-terminal domain 0.57 50.0 4.58e-01 100.0% 77.0%
1h72C02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.57 52.0 3.84e-01 100.0% 70.4%
3e3vA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 44.0 4.47e-01 94.6% 92.9%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3931593 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.80 70.0 6.28e-01 100.0% 80.0%
4325839 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.79 69.0 6.46e-01 100.0% 84.3%
3374031 109.27.1.0 alpha superhelices › Repetitive alpha hairpins › BACK domain › BACK domain 0.71 61.0 4.77e-01 98.2% 45.0%
None 0.64 53.0 3.67e-01 100.0% 33.6%
D6 medium residues 351-441
PDB
Domain cluster: representative
CATH (55)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2hr2A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.90 63.0 5.07e-01 71.4% 44.9%
2qfcA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.90 60.0 4.04e-01 71.4% 21.8%
3ro3A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.89 59.0 4.76e-01 71.4% 39.0%
2v6yA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.88 63.0 6.92e-01 73.6% 100.0%
3u8vA00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.88 61.0 6.38e-01 72.5% 78.3%
4nq0A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.88 64.0 4.49e-01 75.8% 28.7%
1a17A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.87 55.0 4.42e-01 72.5% 36.5%
1kt1A03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.87 59.0 4.74e-01 76.9% 39.9%
3gw4A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.86 58.0 4.42e-01 71.4% 32.8%
6t0bc02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.84 60.0 4.61e-01 73.6% 51.8%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.84 62.0 6.20e-01 76.9% 98.9%
3ceqA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.83 57.0 4.02e-01 70.3% 26.0%
3oxfA05 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.83 59.0 6.55e-01 74.7% 89.3%
2ifuD00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.83 58.0 4.04e-01 76.9% 24.4%
2fbnA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.82 59.0 4.83e-01 73.6% 49.7%
7nmqA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.81 62.0 4.07e-01 80.2% 75.4%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.81 58.0 5.67e-01 74.7% 68.0%
6adqG01 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.81 60.0 4.70e-01 76.9% 58.4%
1xg2B00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.81 60.0 4.96e-01 76.9% 55.0%
2uubT00 1.20.58.110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 0.81 59.0 5.75e-01 75.8% 81.8%
2c2lA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.81 56.0 4.85e-01 75.8% 48.9%
2rpaA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.80 56.0 6.09e-01 72.5% 97.4%
2jbwA01 1.20.1440.110 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase 0.80 58.0 5.52e-01 74.7% 72.8%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.79 61.0 6.07e-01 80.2% 87.1%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.79 57.0 6.15e-01 75.8% 100.0%
1ug7A00 1.20.120.360 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Axin interactor, dorsalization-associated protein, N-terminal domain 0.79 56.0 4.95e-01 73.6% 65.6%
2katA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.79 52.0 4.81e-01 70.3% 53.9%
2xl4A00 1.20.120.1420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › LntA helical domain 0.78 55.0 4.69e-01 73.6% 67.3%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.78 55.0 5.32e-01 73.6% 94.1%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.77 55.0 5.73e-01 75.8% 97.6%
3n71A03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.76 61.0 4.55e-01 84.6% 86.9%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.76 57.0 5.45e-01 78.0% 96.1%
1nafA02 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 51.0 5.33e-01 70.3% 100.0%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.75 59.0 5.78e-01 82.4% 87.6%
2wpvE00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.75 52.0 3.60e-01 72.5% 23.2%
3ggyA00 1.20.1260.60 Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 0.74 52.0 4.03e-01 72.5% 91.9%
2a9uA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.74 60.0 5.31e-01 85.7% 75.4%
7ru9C01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.73 51.0 3.59e-01 72.5% 24.3%
3lpzA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.73 51.0 3.49e-01 71.4% 21.9%
3c18A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.73 52.0 4.72e-01 73.6% 72.9%
3rauA00 1.25.40.280 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › alix/aip1 like domains 0.72 63.0 4.15e-01 95.6% 27.1%
7qocA01 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.72 55.0 4.30e-01 80.2% 59.4%
5ohzA00 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.71 64.0 4.11e-01 98.9% 57.1%
4i17A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.69 52.0 3.88e-01 80.2% 44.6%
1yw0A00 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 48.0 3.51e-01 74.7% 67.9%
2hsbA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.66 49.0 4.34e-01 76.9% 80.2%
2wwxB00 1.20.1260.70 Mainly Alpha › Up-down Bundle › Ferritin › 0.65 51.0 3.93e-01 83.5% 83.5%
3o10C00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.64 48.0 4.18e-01 78.0% 81.6%
1o3uA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.64 44.0 3.93e-01 70.3% 98.3%
2yhcA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.63 55.0 4.07e-01 92.3% 41.1%
2nrjA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.61 48.0 3.41e-01 89.0% 67.3%
3agtA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.61 44.0 3.91e-01 74.7% 63.9%
3teqB00 1.10.287.3550 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.61 42.0 4.08e-01 70.3% 86.1%
1wolA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.61 47.0 4.22e-01 80.2% 80.3%
1at9A00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.51 43.0 3.35e-01 100.0% 76.5%
ECOD (77)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5022166 109.4.1.922 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_9 0.93 69.0 4.71e-01 76.9% 30.2%
3270441 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.92 64.0 7.08e-01 71.4% 100.0%
3883622 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.91 62.0 6.84e-01 70.3% 100.0%
5055533 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.90 68.0 5.73e-01 79.1% 50.7%
5055922 109.7.1.0 alpha superhelices › Repetitive alpha hairpins › Cytochrome c oxidase subunit E › Cytochrome c oxidase subunit E 0.89 69.0 5.39e-01 81.3% 41.7%
5072449 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.89 72.0 7.31e-01 84.6% 95.6%
5049135 109.7.1.0 alpha superhelices › Repetitive alpha hairpins › Cytochrome c oxidase subunit E › Cytochrome c oxidase subunit E 0.88 61.0 6.85e-01 71.4% 91.4%
3990840 109.4.1.1844 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_10, TPR_12 0.88 63.0 4.14e-01 73.6% 25.3%
3603137 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.87 66.0 5.31e-01 80.2% 43.6%
3597100 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.87 60.0 4.93e-01 71.4% 44.8%
4025864 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.86 61.0 4.15e-01 72.5% 23.2%
3341387 109.4.1.5 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1 0.86 62.0 4.97e-01 73.6% 46.3%
3435470 109.4.1.2075 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_2, TPR_19 0.86 63.0 4.59e-01 75.8% 30.7%
5053124 109.7.1.0 alpha superhelices › Repetitive alpha hairpins › Cytochrome c oxidase subunit E › Cytochrome c oxidase subunit E 0.86 61.0 6.65e-01 73.6% 88.0%
3621994 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.86 66.0 5.68e-01 80.2% 59.3%
3583659 109.4.1.1735 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_8, TPR_12, TPR_16 0.85 63.0 5.36e-01 76.9% 72.1%
4556629 601.18.1.26 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › PF30890 0.85 60.0 6.12e-01 74.7% 74.4%
3884438 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.84 62.0 6.60e-01 75.8% 97.5%
3268622 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.84 65.0 6.20e-01 81.3% 81.0%
3504178 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.83 58.0 5.07e-01 71.4% 50.0%
151899 109.4.1.1473 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_11, TPR_12 0.83 58.0 5.13e-01 72.5% 74.0%
3497845 109.4.1.1474 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_6, TPR_16 0.83 60.0 3.96e-01 75.8% 23.1%
3407072 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.83 61.0 6.49e-01 76.9% 100.0%
3605813 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.81 59.0 4.80e-01 75.8% 44.2%
None 0.81 57.0 3.70e-01 72.5% 26.5%
3246163 109.4.1.1286 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_12 0.81 59.0 3.92e-01 75.8% 23.9%
4943123 604.12.1.134 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › AAA 0.81 64.0 6.66e-01 82.4% 100.0%
4997237 109.4.1.95 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2 0.81 59.0 5.52e-01 75.8% 72.7%
3527051 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.81 65.0 6.46e-01 84.6% 90.5%
3919009 109.4.1.1509 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_12, TPR_16 0.81 57.0 4.82e-01 72.5% 67.1%
4159500 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.81 64.0 6.63e-01 82.4% 100.0%
None 0.81 57.0 3.72e-01 72.5% 27.6%
None 0.81 57.0 3.74e-01 72.5% 28.5%
3548485 101.3.1.0 alpha arrays › HTH › XPC-binding domain › XPC-binding domain 0.81 57.0 3.71e-01 72.5% 28.1%
3171229 101.3.1.0 alpha arrays › HTH › XPC-binding domain › XPC-binding domain 0.80 56.0 3.41e-01 72.5% 18.5%
3813462 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.79 54.0 4.70e-01 70.3% 50.4%
3618422 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.79 64.0 3.77e-01 84.6% 12.6%
None 0.79 58.0 3.71e-01 75.8% 26.2%
3436790 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.79 63.0 5.06e-01 84.6% 46.5%
3499593 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.79 66.0 7.00e-01 93.4% 100.0%
3484071 604.13.1.0 alpha bundles › Spectrin repeat-like › USP8 N-terminal domain-like › USP8 N-terminal domain-like 0.79 64.0 5.62e-01 85.7% 70.0%
5056292 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.79 61.0 5.44e-01 81.3% 88.0%
5076728 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.79 59.0 3.91e-01 81.3% 21.2%
None 0.79 58.0 3.73e-01 76.9% 27.1%
5029773 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.79 54.0 5.89e-01 70.3% 97.3%
3992169 109.4.1.2609 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_8, TPR_12, TPR_17 0.79 58.0 4.77e-01 76.9% 67.7%
3544553 109.4.1.368 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SHNi-TPR 0.78 65.0 4.55e-01 87.9% 30.7%
3695480 109.4.1.1666 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_10 0.78 57.0 4.25e-01 74.7% 75.1%
None 0.78 58.0 3.73e-01 76.9% 27.5%
3691909 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.78 58.0 5.01e-01 76.9% 76.3%
None 0.78 59.0 3.87e-01 79.1% 30.3%
None 0.78 59.0 3.80e-01 79.1% 28.3%
None 0.77 59.0 3.81e-01 79.1% 29.4%
3739941 109.4.1.8 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1,TPR_12 0.77 57.0 4.56e-01 76.9% 61.2%
3865100 109.4.1.368 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SHNi-TPR 0.77 65.0 4.43e-01 89.0% 28.1%
4877620 604.13.1.1 alpha bundles › Spectrin repeat-like › USP8 N-terminal domain-like › USP8 N-terminal domain-like › USP8_dimer 0.77 60.0 5.34e-01 82.4% 77.2%
3923922 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.77 54.0 5.83e-01 72.5% 98.7%
3394532 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.76 59.0 4.40e-01 80.2% 51.7%
3633107 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.75 51.0 5.09e-01 70.3% 74.7%
3461517 109.4.1.373 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › COG4_m 0.74 65.0 4.11e-01 96.7% 20.0%
4946563 109.4.1.198 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12 0.74 61.0 4.07e-01 87.9% 84.2%
3272556 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.73 66.0 5.01e-01 100.0% 44.6%
3797502 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.73 62.0 3.73e-01 89.0% 78.9%
5049222 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.72 55.0 3.78e-01 81.3% 23.9%
3737583 109.4.1.44 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps35 0.72 54.0 3.34e-01 79.1% 15.9%
3463676 109.4.1.1186 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF6857 0.72 54.0 4.55e-01 80.2% 56.1%
3494695 109.4.1.44 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps35 0.70 51.0 3.03e-01 75.8% 12.4%
3815482 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.69 61.0 3.93e-01 94.5% 53.1%
3413348 109.4.1.3511 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › L27 0.69 63.0 3.75e-01 100.0% 15.0%
4437441 109.4.1.1333 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps35, PF27614 0.69 51.0 3.51e-01 76.9% 27.0%
3504528 109.4.1.1333 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps35, PF27614 0.69 51.0 3.24e-01 79.1% 17.3%
3926031 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.64 57.0 5.68e-01 98.9% 93.7%
3586131 109.4.1.1333 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps35, PF27614 0.62 50.0 2.91e-01 100.0% 9.8%
3964037 628.1.1.1 alpha bundles › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › FCD 0.62 42.0 3.59e-01 70.3% 80.0%
3702456 109.4.1.44 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps35 0.58 52.0 3.20e-01 100.0% 17.3%
3781527 109.4.1.44 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps35 0.57 52.0 3.60e-01 100.0% 40.0%
3515411 3877.1.1.0 alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC 0.52 40.0 3.13e-01 82.4% 92.7%