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OR842557.1__WQZ01033.1__04086_4582__00039

Bact-Vir

OR842557.1__WQZ01033.1__04086_4582__00039

Identity

Accession:
OR842557 ↗
Kingdom:
phage

Quality

94.6 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 122-216
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00521.27 best DNA_topoisoIV 32.4 6.80e-08 99.0% 19.3%
CATH (74)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3qx3B03 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.87 81.0 7.94e-01 100.0% 93.0%
8gccA02 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.86 74.0 7.76e-01 92.6% 98.8%
3l4jA04 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.84 79.0 7.73e-01 100.0% 93.1%
3lpxB02 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.75 66.0 6.66e-01 94.7% 95.7%
6bq9A02 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.71 62.0 6.23e-01 94.7% 95.7%
3tf8B00 3.90.1520.10 Alpha Beta › Alpha-Beta Complex › H-NOX domain › H-NOX domain 0.68 49.0 3.92e-01 74.7% 45.1%
3onqA02 3.30.70.2730 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 46.0 4.96e-01 80.0% 84.0%
1xppD00 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.67 49.0 4.81e-01 85.3% 72.3%
2l48A00 3.30.70.2030 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 43.0 4.55e-01 78.9% 74.1%
2p5vA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.66 44.0 4.64e-01 77.9% 77.4%
2kl8A00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.66 46.0 4.85e-01 78.9% 81.2%
4qjvB00 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.65 48.0 4.92e-01 84.2% 79.8%
2yweA03 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.65 47.0 4.98e-01 78.9% 86.6%
4ctaA02 3.30.70.2860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 43.0 4.71e-01 77.9% 86.7%
4ezeB00 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.64 44.0 3.12e-01 80.0% 23.2%
2if1A00 3.30.780.10 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain 0.63 49.0 4.51e-01 98.9% 63.5%
3ezjA02 3.30.1370.120 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.63 42.0 4.81e-01 80.0% 97.1%
2yweA04 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 41.0 3.90e-01 78.9% 55.3%
2kwaA00 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.63 52.0 5.12e-01 91.6% 95.0%
5w2fA01 3.30.780.10 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain 0.63 47.0 4.93e-01 87.4% 88.4%
6gmhK00 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.62 49.0 4.61e-01 94.7% 69.6%
2efpA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.62 42.0 4.22e-01 78.9% 67.3%
2cdqA03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.62 47.0 4.91e-01 88.4% 91.7%
2dgrA01 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.62 42.0 4.75e-01 78.9% 100.0%
2cveA02 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 39.0 4.42e-01 77.9% 90.9%
3va7A05 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.62 51.0 5.04e-01 97.9% 85.0%
4dezA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.61 43.0 4.29e-01 78.9% 69.7%
4binA01 2.60.40.3500 Mainly Beta › Sandwich › Immunoglobulin-like › 0.61 45.0 4.25e-01 90.5% 63.8%
2kjwA00 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.61 45.0 4.49e-01 81.1% 76.0%
2dt9A01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.61 43.0 4.75e-01 87.4% 97.3%
2phcB01 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.60 48.0 5.05e-01 87.4% 97.6%
2qmaA02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.60 48.0 4.40e-01 88.4% 65.6%
2j0wA03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.60 45.0 4.75e-01 88.4% 93.8%
1dq3A04 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.59 44.0 4.23e-01 80.0% 68.4%
2ebbA00 3.30.1360.20 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase 0.59 47.0 4.71e-01 88.4% 85.4%
4qmfB01 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.59 42.0 4.50e-01 78.9% 87.8%
5o5cB02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.58 46.0 4.18e-01 88.4% 63.3%
2ogkD00 3.30.1440.10 Alpha Beta › 2-Layer Sandwich › 50s Ribosomal Protein L5; Chain: A, › Ribosomal protein L5 0.58 43.0 3.84e-01 80.0% 78.9%
4i68A00 3.30.70.1800 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 38.0 3.97e-01 82.1% 71.1%
5mmiU01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.57 42.0 4.51e-01 78.9% 96.3%
5i2cB01 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.57 46.0 3.99e-01 86.3% 93.2%
1zhvA00 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.57 45.0 4.05e-01 86.3% 91.0%
1kn6A00 3.30.70.850 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Peptidase S8, pro-domain 0.57 38.0 4.22e-01 77.9% 90.4%
2g0iA00 3.30.70.1490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp 0.57 46.0 4.41e-01 89.5% 87.4%
2p92A00 3.30.70.1490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp 0.56 46.0 4.62e-01 89.5% 89.5%
4g6tA00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.56 44.0 4.11e-01 88.4% 69.5%
4e1oA03 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.56 43.0 4.35e-01 97.9% 81.6%
4v1al00 3.30.780.10 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain 0.56 49.0 4.47e-01 100.0% 81.2%
4hqeA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.56 41.0 3.96e-01 75.8% 71.4%
3tviA02 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.55 45.0 3.84e-01 89.5% 95.0%
3aawA02 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.55 45.0 3.79e-01 89.5% 93.3%
5g4iB01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.55 44.0 3.76e-01 91.6% 53.1%
1js3A03 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.55 43.0 4.28e-01 89.5% 83.5%
1fpqA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 40.0 3.67e-01 77.9% 67.4%
2y8yA01 3.30.70.1200 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Crispr-associated protein; domain 1 0.54 39.0 4.06e-01 78.9% 83.7%
2g47A03 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.54 44.0 3.39e-01 89.5% 88.1%
2wnyA00 3.30.1440.10 Alpha Beta › 2-Layer Sandwich › 50s Ribosomal Protein L5; Chain: A, › Ribosomal protein L5 0.54 40.0 3.62e-01 80.0% 79.6%
2dgkA02 3.90.1150.160 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › 0.53 43.0 4.17e-01 89.5% 84.1%
1ub9A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 38.0 3.75e-01 73.7% 70.0%
2plgA01 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.53 42.0 3.81e-01 86.3% 73.5%
5hs7B00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 38.0 3.85e-01 75.8% 73.5%
3hbxA03 3.90.1150.160 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › 0.53 43.0 4.41e-01 90.5% 97.7%
1s12A00 3.30.70.1490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp 0.53 41.0 4.15e-01 88.4% 86.2%
2jisA01 3.90.1150.170 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › 0.53 45.0 3.47e-01 97.9% 40.2%
4esbA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 39.0 3.82e-01 76.8% 77.7%
3elkA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 38.0 3.72e-01 75.8% 74.3%
1zodA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.53 46.0 4.03e-01 96.8% 88.7%
5e1wA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 40.0 3.33e-01 82.1% 60.7%
1hbxA01 3.40.1810.10 Alpha Beta › 3-Layer(aba) Sandwich › SRF-like › Transcription factor, MADS-box 0.52 29.0 3.21e-01 76.8% 67.6%
6abqB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 38.0 3.71e-01 76.8% 75.5%
1wjwA01 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.52 38.0 3.95e-01 77.9% 96.5%
5h20A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 37.0 3.66e-01 75.8% 75.7%
4h5bA00 3.30.1460.70 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.52 44.0 3.90e-01 100.0% 69.1%
3kxyJ00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.50 42.0 3.90e-01 100.0% 72.1%
ECOD (86)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4878007 101.1.2.9 alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV 0.98 91.0 7.71e-01 96.8% 64.1%
4887990 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.98 92.0 7.40e-01 100.0% 57.1%
3594650 4014.1.1.0 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase 0.89 80.0 6.49e-01 100.0% 55.6%
3998667 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.89 85.0 6.45e-01 100.0% 51.8%
3719735 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.88 82.0 6.59e-01 100.0% 55.8%
3614277 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.87 77.0 6.09e-01 100.0% 49.4%
2390536 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.86 77.0 6.27e-01 95.8% 54.9%
3277529 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.86 79.0 6.46e-01 100.0% 57.5%
3789606 4014.1.1.0 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase 0.85 81.0 6.48e-01 100.0% 57.1%
3220665 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.81 75.0 6.04e-01 100.0% 57.7%
3096551 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.81 75.0 5.91e-01 100.0% 54.1%
4266765 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.76 70.0 5.77e-01 100.0% 58.2%
5058039 305.1.1.1 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L 0.69 52.0 5.45e-01 87.4% 89.4%
3528591 304.24.1.24 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › V-ATPase_C 0.68 49.0 4.77e-01 81.1% 67.6%
4273759 305.1.1.2 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L_2 0.67 50.0 4.93e-01 94.7% 74.7%
4618856 305.1.1.2 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L_2 0.67 49.0 4.86e-01 85.3% 73.0%
4386736 305.1.1.2 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L_2 0.67 49.0 4.97e-01 84.2% 78.5%
4969412 305.1.1.2 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L_2 0.67 48.0 4.82e-01 84.2% 72.7%
5041224 306.2.1.0 a+b two layers › Glucose permease domain IIB-like › arginine repressor C terminal domain-related › C-terminal domain of arginine repressor 0.67 50.0 5.26e-01 82.1% 88.2%
4954138 305.1.1.2 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L_2 0.67 48.0 5.09e-01 84.2% 85.9%
5038336 305.1.1.2 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L_2 0.66 48.0 4.98e-01 94.7% 81.1%
3318862 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.66 51.0 5.34e-01 89.5% 91.8%
4130677 304.162.1.1 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH 0.66 44.0 4.96e-01 77.9% 92.9%
3307802 306.3.1.1 a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 0.66 50.0 5.24e-01 98.9% 87.5%
5040160 305.1.1.2 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L_2 0.66 50.0 4.91e-01 87.4% 76.0%
4029970 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.66 47.0 5.07e-01 78.9% 88.7%
4505080 242.1.1.2 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_2 0.65 47.0 4.29e-01 74.7% 70.4%
5035806 305.1.1.2 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L_2 0.65 49.0 5.00e-01 87.4% 83.3%
3967558 306.6.1.1 a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like › CT_C_D 0.65 51.0 5.41e-01 87.4% 94.1%
4416349 304.162.1.1 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH 0.65 46.0 4.97e-01 78.9% 87.5%
4523274 304.24.1.1 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › EFG_C 0.65 46.0 3.67e-01 78.9% 36.4%
5046930 305.1.1.2 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L_2 0.65 47.0 4.75e-01 84.2% 76.8%
4994876 306.6.1.1 a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like › CT_C_D 0.65 50.0 5.26e-01 88.4% 91.8%
3824912 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.65 50.0 5.39e-01 98.9% 98.8%
4063927 304.24.1.1 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › EFG_C 0.65 46.0 3.68e-01 78.9% 37.4%
4133554 304.24.1.21 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › EFG_C+EFG_III 0.64 46.0 3.66e-01 78.9% 37.4%
3253387 305.1.1.2 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L_2 0.64 51.0 5.12e-01 88.4% 85.3%
3438815 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.64 51.0 5.36e-01 89.5% 95.3%
3434168 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.64 58.0 5.62e-01 100.0% 93.3%
3274720 206.1.1.49 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › DUF5898 0.64 51.0 4.00e-01 86.3% 59.5%
3171307 306.3.1.1 a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 0.64 51.0 4.80e-01 91.6% 71.3%
3381288 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.64 45.0 4.79e-01 78.9% 83.5%
3275539 206.1.1.49 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › DUF5898 0.63 51.0 3.82e-01 87.4% 51.9%
4092153 304.162.1.1 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH 0.63 45.0 4.68e-01 77.9% 80.0%
3283785 306.6.1.1 a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like › CT_C_D 0.62 51.0 5.28e-01 98.9% 93.3%
3445077 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.62 50.0 5.31e-01 86.3% 100.0%
4292806 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.62 50.0 4.90e-01 89.5% 84.8%
3641694 306.3.1.1 a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 0.62 51.0 4.94e-01 94.7% 81.0%
2595266 241.1.1.6 a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › YbjN 0.61 49.0 4.37e-01 86.3% 72.6%
1954213 241.1.1.6 a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › YbjN 0.61 49.0 4.26e-01 86.3% 67.6%
4350854 218.1.1.8 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA 0.61 36.0 3.48e-01 90.5% 51.4%
3688090 306.6.1.1 a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like › CT_C_D 0.61 50.0 5.11e-01 97.9% 94.4%
3739949 306.6.1.0 a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like 0.60 47.0 4.96e-01 85.3% 96.5%
1152767 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.60 48.0 4.63e-01 88.4% 76.6%
3588048 304.156.1.0 a+b two layers › Alpha-beta plaits › DNA translocase FtsK N-terminal domain › DNA translocase FtsK N-terminal domain 0.60 42.0 4.13e-01 73.7% 81.0%
3445332 304.8.1.21 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_9 0.59 44.0 4.42e-01 81.1% 77.9%
3841538 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.59 43.0 4.25e-01 81.1% 73.0%
5261 304.8.1.2 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.58 42.0 4.31e-01 82.1% 79.1%
3692327 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.58 42.0 4.38e-01 81.1% 84.7%
3944118 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.58 40.0 4.11e-01 70.5% 80.0%
3399731 3016.1.1.21 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › PDXDC1-like_cen 0.57 46.0 4.01e-01 89.5% 98.7%
3838105 304.14.1.1 a+b two layers › Alpha-beta plaits › Sporulation related repeat (SPOR) › Sporulation related repeat (SPOR) › SPOR 0.57 38.0 4.23e-01 77.9% 91.4%
3942754 304.8.1.21 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_9 0.57 41.0 4.37e-01 78.9% 90.0%
3284992 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.57 46.0 4.74e-01 90.5% 94.3%
4297454 306.3.1.2 a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › Img2 0.57 51.0 4.49e-01 98.9% 77.5%
1018784 241.1.1.3 a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › CesT 0.56 44.0 4.11e-01 88.4% 69.5%
5036255 241.1.1.0 a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone 0.56 46.0 4.36e-01 90.5% 75.7%
3172743 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.56 42.0 4.18e-01 81.1% 79.0%
4980206 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.56 38.0 4.08e-01 78.9% 82.5%
3477161 5104.1.1.3 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA2 0.56 48.0 4.22e-01 100.0% 92.0%
3486967 5104.1.1.0 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases 0.56 48.0 4.22e-01 100.0% 92.0%
5011597 101.1.2.143 alpha arrays › HTH › HTH › winged helix domain › HTH_34 0.55 40.0 4.01e-01 75.8% 73.7%
3969151 304.14.1.1 a+b two layers › Alpha-beta plaits › Sporulation related repeat (SPOR) › Sporulation related repeat (SPOR) › SPOR 0.55 38.0 4.09e-01 77.9% 86.3%
5083337 101.1.2.14 alpha arrays › HTH › HTH › winged helix domain › HTH_5 0.55 38.0 3.86e-01 72.6% 71.6%
5005295 101.1.2.101 alpha arrays › HTH › HTH › winged helix domain › Cdc6_C 0.54 37.0 3.40e-01 70.5% 71.5%
4955182 101.1.2.143 alpha arrays › HTH › HTH › winged helix domain › HTH_34 0.54 39.0 3.84e-01 73.7% 71.0%
3602557 101.1.2.143 alpha arrays › HTH › HTH › winged helix domain › HTH_34 0.54 38.0 3.97e-01 73.7% 78.9%
5077595 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.54 40.0 3.89e-01 81.1% 80.9%
4991130 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.54 39.0 3.51e-01 75.8% 56.9%
139726 241.1.1.3 a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › CesT 0.53 42.0 3.86e-01 89.5% 69.9%
5077919 101.1.2.143 alpha arrays › HTH › HTH › winged helix domain › HTH_34 0.53 38.0 3.81e-01 75.8% 73.0%
5010964 101.1.2.143 alpha arrays › HTH › HTH › winged helix domain › HTH_34 0.52 38.0 3.78e-01 75.8% 73.0%
3106398 206.1.2.3 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › IPK 0.52 41.0 3.25e-01 88.4% 82.5%
3626001 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.52 44.0 4.11e-01 97.9% 78.0%
4954761 241.1.1.0 a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone 0.52 43.0 4.07e-01 100.0% 77.5%
2409292 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.50 40.0 3.90e-01 86.3% 91.3%
D2 medium residues 42-69_219-262
PDB
Domain cluster: representative
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1bjtA05 3.90.199.10 Alpha Beta › Alpha-Beta Complex › Topoisomerase II; domain 5 › Topoisomerase II, domain 5 0.87 73.0 4.87e-01 88.9% 46.2%
4bqqA01 3.40.50.1390 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Resolvase, N-terminal catalytic domain 0.60 46.0 3.77e-01 84.7% 92.1%
5ziyA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.56 48.0 3.55e-01 94.4% 75.8%
2r31A01 3.30.2180.10 Alpha Beta › 2-Layer Sandwich › ATP12-like › ATP12-like 0.55 38.0 4.01e-01 76.4% 80.3%
1f02T00 4.10.820.10 Few Secondary Structures › Irregular › Translocated Intimin Receptor; Chain T › Translocated intimin receptor, central domain 0.53 42.0 4.41e-01 91.7% 92.4%
4i0wB01 3.40.50.200 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Peptidase S8/S53 domain 0.52 44.0 2.90e-01 95.8% 83.5%
6erkA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.51 42.0 3.30e-01 91.7% 50.9%
6zhhA01 3.40.1110.10 Alpha Beta › 3-Layer(aba) Sandwich › Calcium-transporting ATPase, cytoplasmic domain N › Calcium-transporting ATPase, cytoplasmic domain N 0.51 40.0 3.07e-01 87.5% 98.3%
3hwcA01 1.10.3140.10 Mainly Alpha › Orthogonal Bundle › 4-hydroxybutyryl-coa dehydratase, domain 1 › 4-hydroxybutyryl-coa dehydratase, domain 1 0.50 37.0 2.94e-01 91.7% 38.1%
ECOD (14)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5057974 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.66 57.0 4.84e-01 94.4% 78.3%
3544534 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.62 42.0 4.11e-01 94.4% 63.7%
3862747 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.60 47.0 4.40e-01 93.1% 69.4%
3691304 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.59 46.0 3.08e-01 83.3% 74.0%
3954708 4325.1.1.9 mixed a+b and a/b › YegP-like › YegP-like › YegP-like › PF26003 0.56 38.0 4.48e-01 83.3% 100.0%
3565062 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.55 39.0 3.17e-01 91.7% 39.3%
3470968 109.1.1.0 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C 0.54 44.0 3.20e-01 90.3% 51.2%
4282188 5059.1.1.59 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EmrE 0.54 48.0 3.18e-01 100.0% 59.7%
5001324 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.54 41.0 3.62e-01 86.1% 56.2%
3488181 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.53 47.0 3.95e-01 98.6% 79.2%
3903618 219.1.1.54 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C98 0.53 46.0 3.09e-01 97.2% 35.2%
3633245 10.12.1.52 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › Cupin_8 0.53 43.0 2.68e-01 87.5% 88.9%
4251053 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.52 41.0 2.82e-01 87.5% 56.5%
4591467 885.1.1.1 a+b complex topology › Transcription factor NusA, N-terminal domain › Transcription factor NusA, N-terminal domain › Transcription factor NusA, N-terminal domain › NusA_N 0.50 43.0 3.64e-01 97.2% 96.8%
D3 medium residues 70-121
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00521.27 best DNA_topoisoIV 36.5 3.90e-09 100.0% 11.6%
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1bjtA05 3.90.199.10 Alpha Beta › Alpha-Beta Complex › Topoisomerase II; domain 5 › Topoisomerase II, domain 5 0.93 80.0 4.94e-01 92.3% 19.3%
1uqtA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.65 48.0 3.18e-01 84.6% 29.6%
1zcdA00 1.20.1530.10 Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › Na+/H+ antiporter like domain 0.63 44.0 2.68e-01 75.0% 31.4%
3qthB00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.59 40.0 2.80e-01 71.2% 39.0%
6pexA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.58 44.0 3.24e-01 80.8% 60.9%
3va7A04 2.40.100.10 Mainly Beta › Beta Barrel › Cyclophilin › Cyclophilin-like 0.56 42.0 3.22e-01 92.3% 96.9%
2vvlG01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.56 45.0 2.86e-01 88.5% 70.3%
1qmgB01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.53 39.0 2.71e-01 86.5% 64.8%
2pmeA01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.53 40.0 2.47e-01 82.7% 21.0%
8dvhB01 3.30.230.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.51 44.0 3.08e-01 100.0% 58.1%
3loyA01 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.50 43.0 3.51e-01 98.1% 85.1%
ECOD (28)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4878007 101.1.2.9 alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV 0.98 92.0 6.37e-01 98.1% 35.9%
3998667 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.93 85.0 5.57e-01 100.0% 26.7%
3719735 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.93 85.0 5.79e-01 100.0% 31.5%
3188905 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.91 83.0 5.57e-01 100.0% 33.3%
2390536 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.91 83.0 5.67e-01 100.0% 32.1%
3594650 4014.1.1.0 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase 0.90 83.0 5.71e-01 100.0% 35.0%
3789606 4014.1.1.0 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase 0.90 83.0 5.60e-01 100.0% 30.6%
4266765 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.90 80.0 5.43e-01 100.0% 30.3%
3277529 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.90 81.0 5.63e-01 100.0% 33.1%
3220665 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.90 82.0 5.54e-01 100.0% 30.3%
3965475 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.86 79.0 5.12e-01 100.0% 28.3%
4624017 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.85 78.0 5.26e-01 100.0% 32.8%
3962339 4014.1.1.0 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase 0.85 78.0 5.18e-01 100.0% 34.1%
4946212 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.85 77.0 5.17e-01 100.0% 31.4%
4024263 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.84 77.0 4.97e-01 100.0% 27.0%
396210 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.84 76.0 4.83e-01 100.0% 25.8%
3096551 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.78 68.0 4.63e-01 100.0% 36.2%
3633209 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.75 53.0 5.03e-01 92.3% 63.3%
3742786 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.75 50.0 4.95e-01 88.5% 65.5%
3202360 2003.1.4.5 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › SIR2 0.69 53.0 3.18e-01 92.3% 12.7%
3689856 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.68 50.0 4.78e-01 90.4% 68.3%
3735204 2003.1.4.5 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › SIR2 0.63 50.0 3.06e-01 92.3% 13.7%
3268456 109.6.1.0 alpha superhelices › Repetitive alpha hairpins › Ras GEF › Ras GEF 0.63 34.0 2.40e-01 71.2% 18.1%
3408740 2485.1.1.34 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Rdx 0.62 54.0 4.41e-01 98.1% 91.6%
4107494 235.1.1.5 a+b complex topology › Lysozyme-like › Lysozyme-like › Lysozyme-like › Transgly 0.58 46.0 3.06e-01 82.7% 63.3%
170260 2003.1.5.151 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23, Methyltransf_25 0.52 35.0 2.43e-01 73.1% 44.8%
4398690 268.2.1.1 a+b two layers › Sterol carrier protein-like › LytR-Cps2A-Psr (LCP) enzymes › LytR-Cps2A-Psr (LCP) enzymes › LytR_cpsA_psr 0.51 40.0 2.56e-01 96.2% 58.7%
3782414 243.5.1.0 a+b two layers › Cystatin-like › Amine oxidase N-terminal region › Amine oxidase N-terminal region 0.50 44.0 3.53e-01 96.2% 85.0%