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ORF083_early_transcription_factor_VETFL
Euk-VirOrf_virus
ORF083_early_transcription_factor_VETFL__NP_957860__Orf_virus__10258
Identity
- Accession:
- NP_957860 ↗
- Protein ID:
- ORF083_early_transcription_factor_VETFL
- Kingdom:
- euk
Quality
70.8
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Parapoxvirus›
Orf_virus
TaxID: 10258
Cluster
View cluster (30 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 525-598
Domain cluster:
rep: early_transcription_factor_large_subunit_VETF-L__YP_009046167__Penguinpox_virus__648998__D379-458
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04441.20 best | Pox_VERT_large | 132.0 | 3.50e-38 | 100.0% | 10.5% |
D2
high
residues 611-739
Domain cluster:
rep: early_transcription_factor_-VETF-_large_subunit__YP_009162477__Salmon_gill_poxvirus__1680908__D487-623
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04441.20 best | Pox_VERT_large | 164.6 | 4.90e-48 | 100.0% | 18.5% |
D3
medium
residues 143-300
Domain cluster:
rep: early_transcription_factor_-VETF-_large_subunit__YP_009162477__Salmon_gill_poxvirus__1680908__D11-143
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04441.20 best | Pox_VERT_large | 251.3 | 2.80e-74 | 100.0% | 22.4% |
D4
medium
residues 309-347_361-410
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04441.20 best | Pox_VERT_large | 69.0 | 3.80e-19 | 100.0% | 14.1% |
CATH (29)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2yweA03 | 3.30.70.870 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 | 0.63 | 43.0 | 4.50e-01 | 87.6% | 76.8% |
| 3klxB00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.62 | 52.0 | 4.17e-01 | 94.4% | 80.1% |
| 3rheA00 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.61 | 42.0 | 3.89e-01 | 70.8% | 98.2% |
| 2nvmA00 | 3.30.310.110 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › XisI-like | 0.61 | 48.0 | 4.66e-01 | 88.8% | 95.2% |
| 3w9kA00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.61 | 51.0 | 4.43e-01 | 92.1% | 93.3% |
| 2qpvA00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.60 | 51.0 | 4.53e-01 | 95.5% | 95.5% |
| 6f1uK02 | 3.90.1150.210 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › F-actin capping protein, beta subunit | 0.59 | 42.0 | 3.62e-01 | 75.3% | 79.3% |
| 3jcmH04 | 3.30.70.870 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 | 0.58 | 42.0 | 4.45e-01 | 95.5% | 88.3% |
| 1iwmA00 | 2.50.20.10 | Mainly Beta › Clam › outer membrane lipoprotein receptor (LolB), chain A › Lipoprotein localisation LolA/LolB/LppX | 0.57 | 40.0 | 3.24e-01 | 73.0% | 79.1% |
| 1ukfA00 | 3.90.70.20 | Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › | 0.56 | 41.0 | 3.24e-01 | 76.4% | 80.3% |
| 1ah5A03 | 3.30.160.40 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain | 0.56 | 39.0 | 4.01e-01 | 73.0% | 88.4% |
| 3holA01 | 2.40.128.250 | Mainly Beta › Beta Barrel › Lipocalin › | 0.56 | 39.0 | 4.00e-01 | 71.9% | 77.1% |
| 2mcfA00 | 3.40.50.11630 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.54 | 44.0 | 3.79e-01 | 91.0% | 59.5% |
| 3uaqB01 | 2.40.128.250 | Mainly Beta › Beta Barrel › Lipocalin › | 0.54 | 37.0 | 3.49e-01 | 71.9% | 73.6% |
| 1q5qA00 | 3.60.20.10 | Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain | 0.53 | 42.0 | 3.19e-01 | 85.4% | 63.5% |
| 4akrA02 | 3.90.1150.210 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › F-actin capping protein, beta subunit | 0.53 | 40.0 | 3.46e-01 | 82.0% | 78.2% |
| 2kl8A00 | 3.30.70.600 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 | 0.53 | 38.0 | 3.86e-01 | 93.3% | 80.0% |
| 4s3nA01 | 3.30.460.10 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 | 0.52 | 41.0 | 3.57e-01 | 87.6% | 61.2% |
| 4g6vB00 | 3.30.70.2920 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.52 | 45.0 | 4.35e-01 | 98.9% | 93.2% |
| 3tfiA00 | 3.30.1360.120 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Probable tRNA modification gtpase trme; domain 1 | 0.52 | 45.0 | 3.01e-01 | 98.9% | 59.3% |
| 2ltsA00 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.52 | 41.0 | 4.20e-01 | 87.6% | 97.7% |
| 8hbfB01 | 3.90.1520.10 | Alpha Beta › Alpha-Beta Complex › H-NOX domain › H-NOX domain | 0.51 | 45.0 | 3.60e-01 | 98.9% | 59.7% |
| 2rs7A01 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.51 | 35.0 | 3.74e-01 | 70.8% | 100.0% |
| 3v38A00 | 3.40.630.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases | 0.51 | 41.0 | 2.89e-01 | 91.0% | 91.0% |
| 1j2vA00 | 3.30.70.120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.51 | 38.0 | 3.73e-01 | 86.5% | 72.3% |
| 2oqbA00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.51 | 35.0 | 3.34e-01 | 71.9% | 86.1% |
| 2kouA00 | 3.30.160.380 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Dicer dimerisation domain | 0.50 | 38.0 | 3.74e-01 | 84.3% | 91.2% |
| 2n3gA00 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.50 | 35.0 | 3.83e-01 | 73.0% | 100.0% |
| 3cbfA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.50 | 41.0 | 3.39e-01 | 93.3% | 55.4% |
ECOD (40)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3168583 | 3435.1.1.2 ↗ | a+b two layers › Recombination-associated protein rdgC › Recombination-associated protein rdgC › Recombination-associated protein rdgC › CENP-N | 0.71 | 61.0 | 5.43e-01 | 96.6% | 83.8% |
| 3782121 | 3435.1.1.2 ↗ | a+b two layers › Recombination-associated protein rdgC › Recombination-associated protein rdgC › Recombination-associated protein rdgC › CENP-N | 0.70 | 61.0 | 5.08e-01 | 96.6% | 79.9% |
| 3985863 | 219.1.1.109 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Toxin_15 | 0.64 | 47.0 | 3.65e-01 | 78.7% | 72.7% |
| 4063927 | 304.24.1.1 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › EFG_C | 0.64 | 45.0 | 3.51e-01 | 86.5% | 34.2% |
| 4091138 | 304.24.1.3 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › EFG_III | 0.63 | 44.0 | 4.41e-01 | 86.5% | 71.1% |
| 3604410 | 2004.1.1.293 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_15 | 0.63 | 45.0 | 3.55e-01 | 74.2% | 36.7% |
| 3381288 | 304.24.1.0 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like | 0.62 | 44.0 | 4.49e-01 | 86.5% | 76.5% |
| 3585079 | 304.24.1.1 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › EFG_C | 0.62 | 43.0 | 3.36e-01 | 86.5% | 31.7% |
| 4975431 | 331.3.1.0 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like | 0.61 | 46.0 | 4.67e-01 | 80.9% | 87.8% |
| 168173 | 4276.1.1.1 ↗ | a+b two layers › XisI-like › XisI-like › XisI-like › XisI | 0.61 | 49.0 | 4.64e-01 | 88.8% | 96.3% |
| 3596303 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.61 | 42.0 | 4.53e-01 | 70.8% | 94.7% |
| 3263502 | 331.4.1.9 ↗ | a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 › CPSF73-100_C | 0.61 | 51.0 | 5.09e-01 | 93.3% | 94.4% |
| 2472880 | 211.1.1.18 ↗ | a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Diox-like_N | 0.61 | 40.0 | 4.11e-01 | 71.9% | 71.1% |
| 3931696 | 241.4.1.1 ↗ | a+b two layers › Type III secretory system chaperone-like › Hypothetical protein c14orf129, hspc210 › Hypothetical protein c14orf129, hspc210 › GSKIP_dom | 0.59 | 42.0 | 3.97e-01 | 74.2% | 93.3% |
| 3497819 | 316.1.1.16 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DZF_N | 0.59 | 47.0 | 3.69e-01 | 86.5% | 49.5% |
| 4606701 | 7556.1.1.1 ↗ | a/b three-layered sandwiches › Fe-only hydrogenase › Fe-only hydrogenase › Fe-only hydrogenase › Fe_hyd_lg_C | 0.58 | 40.0 | 2.71e-01 | 70.8% | 59.0% |
| 411813 | 3335.1.1.2 ↗ | beta barrels › Handle domain in transferrin-binding protein B › Handle domain in transferrin-binding protein B › Handle domain in transferrin-binding protein B › TbpB_A | 0.58 | 40.0 | 3.75e-01 | 71.9% | 60.5% |
| 3788126 | 241.4.1.1 ↗ | a+b two layers › Type III secretory system chaperone-like › Hypothetical protein c14orf129, hspc210 › Hypothetical protein c14orf129, hspc210 › GSKIP_dom | 0.58 | 42.0 | 4.03e-01 | 77.5% | 86.7% |
| 3221919 | 246.3.1.0 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like | 0.57 | 47.0 | 3.10e-01 | 91.0% | 40.5% |
| 3388541 | 241.4.1.1 ↗ | a+b two layers › Type III secretory system chaperone-like › Hypothetical protein c14orf129, hspc210 › Hypothetical protein c14orf129, hspc210 › GSKIP_dom | 0.57 | 42.0 | 4.14e-01 | 77.5% | 87.4% |
| 3750853 | 330.1.1.18 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › DSRM_DHX29 | 0.57 | 44.0 | 4.06e-01 | 85.4% | 80.0% |
| 4938162 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.56 | 39.0 | 3.95e-01 | 71.9% | 88.9% |
| 3799398 | 241.4.1.1 ↗ | a+b two layers › Type III secretory system chaperone-like › Hypothetical protein c14orf129, hspc210 › Hypothetical protein c14orf129, hspc210 › GSKIP_dom | 0.56 | 41.0 | 3.39e-01 | 77.5% | 69.7% |
| 4023222 | 7556.1.1.0 ↗ | a/b three-layered sandwiches › Fe-only hydrogenase › Fe-only hydrogenase › Fe-only hydrogenase | 0.55 | 40.0 | 2.69e-01 | 78.7% | 58.3% |
| 5055905 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.55 | 38.0 | 3.51e-01 | 71.9% | 67.8% |
| 3741704 | 719.1.1.2 ↗ | beta barrels › XRCC4, N-terminal domain-like › XRCC4, N-terminal domain › XRCC4, N-terminal domain › XLF | 0.54 | 37.0 | 3.32e-01 | 70.8% | 85.4% |
| 3403936 | 241.4.1.1 ↗ | a+b two layers › Type III secretory system chaperone-like › Hypothetical protein c14orf129, hspc210 › Hypothetical protein c14orf129, hspc210 › GSKIP_dom | 0.54 | 39.0 | 3.69e-01 | 76.4% | 91.4% |
| 4133554 | 304.24.1.21 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › EFG_C+EFG_III | 0.53 | 42.0 | 3.37e-01 | 100.0% | 41.1% |
| 4609498 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.52 | 38.0 | 3.93e-01 | 76.4% | 97.5% |
| 3873823 | 316.1.1.16 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DZF_N | 0.52 | 46.0 | 3.54e-01 | 100.0% | 84.8% |
| 3493086 | 3914.1.1.1 ↗ | alpha bundles › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › Anoctamin | 0.52 | 45.0 | 2.74e-01 | 96.6% | 71.7% |
| 3927592 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.52 | 43.0 | 3.84e-01 | 96.6% | 63.1% |
| 4508538 | 7556.1.1.1 ↗ | a/b three-layered sandwiches › Fe-only hydrogenase › Fe-only hydrogenase › Fe-only hydrogenase › Fe_hyd_lg_C | 0.52 | 42.0 | 2.73e-01 | 87.6% | 67.7% |
| 4959370 | 71.1.1.0 ↗ | beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB | 0.52 | 39.0 | 3.22e-01 | 82.0% | 58.9% |
| 4977574 | 241.11.1.7 ↗ | a+b two layers › Type III secretory system chaperone-like › YjbR-like › YjbR-like › DUF3788 | 0.51 | 40.0 | 3.56e-01 | 84.3% | 81.5% |
| 3170447 | 2008.6.1.1 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Acetyl-CoA carboxylase AC4 and AC5 domains › Acetyl-CoA carboxylase AC4 and AC5 domains › ACC_central | 0.51 | 36.0 | 2.63e-01 | 73.0% | 81.2% |
| 138176 | 330.1.1.3 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › Dicer_dimer | 0.50 | 38.0 | 3.74e-01 | 84.3% | 91.2% |
| 3599870 | 216.1.1.0 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like | 0.50 | 37.0 | 3.17e-01 | 80.9% | 65.0% |
| 4104978 | 2004.1.1.73 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 | 0.50 | 40.0 | 3.23e-01 | 88.8% | 70.3% |
| 3231961 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.50 | 37.0 | 3.65e-01 | 77.5% | 80.0% |
D5
medium
residues 411-524
Domain cluster:
rep: early_transcription_factor_82_kDa_subunit__YP_009329732__BeAn_58058_virus__67082__D167-188_236-251_265-357
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04441.20 best | Pox_VERT_large | 211.0 | 4.20e-62 | 100.0% | 16.2% |
D6
medium
residues 748-837
Domain cluster:
rep: putative_A7L_protein__YP_010085794__Orthopoxvirus_Abatino__2478919__D613-700
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04441.20 best | Pox_VERT_large | 84.9 | 5.90e-24 | 100.0% | 11.4% |