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ORF1

Euk-Vir

Lake_Sinai_virus_1

ORF1__YP_009408177__Lake_Sinai_virus_1__1041806

Identity

Accession:
YP_009408177 ↗
Protein ID:
ORF1
Kingdom:
euk

Quality

54.6 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 162-377
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF19223.6 best Chropara_Vmeth 150.9 6.70e-44 88.0% 60.7%
D2 high residues 394-482
PDB
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3fdqA01 1.20.120.1030 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Motility repressor MogR, DNA-binding domain 0.68 41.0 3.70e-01 73.0% 44.3%
3solA00 1.20.58.1630 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chaperone lipoprotein PulS/OutS 0.66 46.0 4.60e-01 71.9% 78.0%
3dd7C00 1.20.120.1870 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Fic/DOC protein, Fido domain 0.63 42.0 3.83e-01 75.3% 49.2%
1t98A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.62 46.0 4.64e-01 78.7% 93.1%
1zp2A02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.61 43.0 4.06e-01 85.4% 58.9%
1sxjE03 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.60 38.0 3.68e-01 79.8% 57.7%
4hehA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.59 38.0 3.96e-01 80.9% 69.9%
2gtvX00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.59 42.0 3.97e-01 73.0% 72.1%
1ldjA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.59 43.0 4.01e-01 78.7% 67.0%
3umcD02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.58 47.0 5.02e-01 89.9% 98.7%
2qwtA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 40.0 3.33e-01 83.1% 38.9%
6wimA02 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.57 40.0 4.33e-01 73.0% 89.2%
2zgyA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.57 39.0 3.35e-01 85.4% 44.3%
5vjhB03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 47.0 3.59e-01 92.1% 92.0%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.57 39.0 3.45e-01 71.9% 94.0%
1a41A02 1.20.120.380 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Type 1-topoisomerase catalytic fragment, domain 2 0.57 42.0 4.18e-01 79.8% 78.7%
2hjmA01 1.20.120.460 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › protein pf1176 like 0.57 42.0 4.29e-01 77.5% 86.0%
2jpnA00 1.20.1280.210 Mainly Alpha › Up-down Bundle › Monooxygenase › Uncharacterised protein UvsW.1 0.56 35.0 3.69e-01 71.9% 69.6%
2i2xB01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.56 37.0 3.57e-01 78.7% 59.0%
3cx5A02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.56 42.0 3.27e-01 84.3% 83.4%
2c0kB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.55 43.0 3.65e-01 84.3% 98.0%
4m0mA03 1.20.1270.430 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.55 39.0 4.14e-01 76.4% 94.9%
3umbA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.55 44.0 4.71e-01 88.8% 98.7%
5z7qA00 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.54 39.0 3.15e-01 75.3% 73.3%
1mhyG02 1.20.1280.30 Mainly Alpha › Up-down Bundle › Monooxygenase › Methane monooxygenase, gamma chain, domain 2 0.54 35.0 3.81e-01 71.9% 82.2%
3ckdA02 1.20.58.360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Shigella T3SS effector IpaH defines 0.53 37.0 3.33e-01 71.9% 58.9%
2zs0A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.52 41.0 3.58e-01 86.5% 98.6%
3tviA01 3.40.1160.10 Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like 0.52 40.0 2.86e-01 82.0% 88.1%
2wy4A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.52 42.0 3.64e-01 88.8% 96.4%
3cz6A01 1.20.120.1480 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.51 40.0 3.81e-01 82.0% 79.8%
3u3iA02 1.20.58.1110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 40.0 3.75e-01 83.1% 70.4%
1yhuB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 42.0 3.70e-01 94.4% 100.0%
3rklA00 6.10.140.1640 Special › Helix non-globular › Helix Hairpins › 0.51 41.0 4.34e-01 91.0% 97.5%
2d2mD00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 41.0 3.57e-01 91.0% 97.2%
3zheC01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.50 34.0 2.77e-01 70.8% 34.2%
ECOD (27)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4105842 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.69 50.0 4.98e-01 76.4% 86.7%
5082325 3705.1.1.3 alpha arrays › Bacterial chaperone lipoprotein (PulS_OutS) › Bacterial chaperone lipoprotein (PulS_OutS) › Bacterial chaperone lipoprotein (PulS_OutS) › Phage_holin_6_1 0.69 51.0 5.64e-01 84.3% 100.0%
3427512 101.1.17.0 alpha arrays › HTH › HTH › FF domain 0.68 47.0 5.26e-01 75.3% 98.5%
3944357 101.1.1.394 alpha arrays › HTH › HTH › Three-helical HTH › DUF4158 0.68 52.0 5.37e-01 96.6% 85.9%
3591764 109.4.1.70 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID 0.66 43.0 3.65e-01 71.9% 41.4%
4167109 149.1.1.1 alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 0.65 55.0 3.46e-01 95.5% 69.3%
3845878 621.1.1.0 alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain 0.63 48.0 5.09e-01 79.8% 98.7%
4093066 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.63 50.0 5.21e-01 87.6% 95.0%
3743679 101.1.1.148 alpha arrays › HTH › HTH › Three-helical HTH › EPL1 0.63 50.0 4.79e-01 87.6% 82.9%
5074875 181.1.1.1 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N 0.62 46.0 4.64e-01 77.5% 81.1%
5029501 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.61 50.0 4.31e-01 89.9% 76.4%
5042713 181.1.1.1 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N 0.60 44.0 4.55e-01 77.5% 84.7%
4396592 7064.1.1.3 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › FUSC_2 0.58 51.0 4.35e-01 98.9% 69.3%
4168740 563.1.1.1 alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP 0.58 49.0 3.96e-01 94.4% 50.0%
4929833 181.1.1.1 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N 0.58 43.0 4.32e-01 78.7% 77.8%
5048002 4953.1.1.0 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like 0.57 50.0 4.45e-01 100.0% 74.1%
4948728 181.1.1.1 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N 0.57 41.0 4.03e-01 75.3% 94.7%
3581597 106.1.1.1 alpha arrays › Globin-like › Globin-like › Globin-like › Globin 0.56 45.0 3.71e-01 86.5% 96.9%
3643664 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.56 40.0 4.35e-01 80.9% 90.7%
3513473 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.55 43.0 3.62e-01 84.3% 68.0%
3510805 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 34.0 2.94e-01 76.4% 37.9%
3970204 304.41.1.0 a+b two layers › Alpha-beta plaits › Glutamyl tRNA-reductase catalytic, N-terminal domain › Glutamyl tRNA-reductase catalytic, N-terminal domain 0.54 40.0 3.38e-01 79.8% 87.1%
4980950 327.5.1.2 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C 0.52 33.0 3.28e-01 83.1% 58.9%
3609900 4351.1.1.1 alpha arrays › ATP12-like › ATP12-like › ATP12-like › ATP12 0.52 45.0 3.34e-01 100.0% 84.1%
4564278 109.4.1.923 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › AEP1 0.51 41.0 2.81e-01 89.9% 30.0%
3705115 2485.1.1.51 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Thioredoxin_14 0.50 45.0 3.24e-01 98.9% 82.4%
5060007 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.50 45.0 3.92e-01 100.0% 67.4%
D3 high residues 697-840
PDB