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ORF1a,_partial
Euk-VirRodent_astrovirus
ORF1a,_partial__YP_009448180__Rodent_astrovirus__1914442
Identity
- Accession:
- YP_009448180 ↗
- Protein ID:
- ORF1a,_partial
- Kingdom:
- euk
Quality
69.5
mean pLDDT
Taxonomy
Orthornavirae›
Pisuviricota›
Stelpaviricetes›
Stellavirales›
Astroviridae›
Mamastrovirus›
Rodent_astrovirus
TaxID: 1914442
Cluster
View cluster (19 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 808-875
Domain cluster:
representative
CATH (22)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4kjmB01 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.69 | 50.0 | 5.15e-01 | 75.0% | 100.0% |
| 2n7zA00 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.68 | 59.0 | 5.18e-01 | 100.0% | 65.1% |
| 6adqG01 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.67 | 54.0 | 3.99e-01 | 88.2% | 92.7% |
| 2etdA00 | 1.20.1440.20 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain | 0.64 | 52.0 | 4.18e-01 | 91.2% | 61.0% |
| 3ce9A02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.62 | 50.0 | 3.75e-01 | 94.1% | 55.7% |
| 2ovjA00 | 1.10.555.10 | Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase; Chain A › Rho GTPase activation protein | 0.62 | 43.0 | 3.12e-01 | 72.1% | 55.2% |
| 4zbwA02 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.62 | 49.0 | 4.61e-01 | 89.7% | 92.0% |
| 2rbdA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.62 | 52.0 | 3.93e-01 | 89.7% | 66.7% |
| 2o71A00 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.61 | 51.0 | 4.75e-01 | 98.5% | 100.0% |
| 1g12A00 | 3.40.390.10 | Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Collagenase (Catalytic Domain) | 0.61 | 49.0 | 3.80e-01 | 92.6% | 90.4% |
| 2psmA00 | 1.20.1250.70 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interleukin-15/Interleukin-21 | 0.60 | 46.0 | 3.97e-01 | 86.8% | 59.0% |
| 2yviA00 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.60 | 50.0 | 4.70e-01 | 98.5% | 98.9% |
| 3h4cA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.58 | 43.0 | 3.92e-01 | 80.9% | 71.9% |
| 5cqfA00 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.58 | 50.0 | 3.11e-01 | 98.5% | 84.7% |
| 3c7jA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.58 | 44.0 | 3.58e-01 | 86.8% | 84.9% |
| 1xo0A01 | 1.10.150.130 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain | 0.57 | 41.0 | 3.46e-01 | 75.0% | 54.1% |
| 5a2gA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.56 | 45.0 | 2.80e-01 | 94.1% | 45.1% |
| 5ix8A01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.56 | 44.0 | 3.42e-01 | 88.2% | 54.1% |
| 1xl7A01 | 1.10.275.20 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Choline/Carnitine o-acyltransferase | 0.53 | 43.0 | 3.76e-01 | 89.7% | 71.8% |
| 2k8oA00 | 1.20.5.2120 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.51 | 36.0 | 3.79e-01 | 88.2% | 88.3% |
| 3pubA01 | 1.10.10.2400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Lepidopteran low molecular weight (30 kD) lipoprotein, N-terminal domain | 0.51 | 36.0 | 3.55e-01 | 75.0% | 75.7% |
| 1aisB02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.51 | 37.0 | 3.46e-01 | 82.4% | 70.2% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3176652 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.71 | 52.0 | 4.93e-01 | 77.9% | 80.0% |
| 4950911 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.69 | 56.0 | 4.43e-01 | 91.2% | 58.6% |
| 4118464 | 4030.1.1.1 ↗ | alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › F_actin_cap_B | 0.63 | 42.0 | 4.64e-01 | 70.6% | 92.7% |
| 3897654 | 5000.4.1.5 ↗ | alpha arrays › Toxins' membrane translocation domains › delta-Endotoxin (insectocide), N-terminal domain › delta-Endotoxin (insectocide), N-terminal domain › PF27742 | 0.62 | 50.0 | 3.44e-01 | 86.8% | 65.2% |
| 3519594 | 223.2.1.19 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like › Intu_longin_1 | 0.61 | 43.0 | 3.38e-01 | 75.0% | 88.4% |
| 5045719 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.60 | 42.0 | 3.49e-01 | 73.5% | 83.1% |
| 5011601 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.57 | 44.0 | 4.27e-01 | 88.2% | 78.8% |
| 4990528 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.52 | 40.0 | 3.79e-01 | 86.8% | 80.0% |
| 5044998 | 2006.1.4.25 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_I | 0.50 | 39.0 | 2.77e-01 | 83.8% | 72.2% |
| 5049771 | 2006.1.4.25 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_I | 0.50 | 38.0 | 2.66e-01 | 82.4% | 57.3% |
D2
medium
residues 1-158
Domain cluster:
representative
D3
medium
residues 236-300
Domain cluster:
representative
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3s63A00 | 1.10.225.10 | Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like | 0.65 | 48.0 | 4.34e-01 | 78.5% | 64.8% |
| 1wgnA00 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.60 | 38.0 | 3.88e-01 | 72.3% | 65.1% |
| 2y44A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.54 | 42.0 | 3.18e-01 | 89.2% | 92.9% |
| 2gbbB00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.53 | 40.0 | 3.19e-01 | 86.2% | 75.5% |
D4
medium
residues 436-510
Domain cluster:
rep: ORF1a__YP_009162618__Dromedary_astrovirus__1662272__D428-481
D5
medium
residues 511-594
Domain cluster:
rep: ORF1a__YP_009047079__Human_astrovirus_BF34__1518575__D522-618