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ORF1a

Euk-Vir

Astrovirus_VA4

ORF1a__YP_006905855__Astrovirus_VA4__1247113

Identity

Accession:
YP_006905855 ↗
Protein ID:
ORF1a
Kingdom:
euk

Quality

70.1 mean pLDDT

Taxonomy

Orthornavirae› Pisuviricota› Stelpaviricetes› Stellavirales› Astroviridae› Astrovirus_VA4

TaxID: 1247113

Cluster

View cluster (8 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 15-136
PDB
Domain cluster: rep: ORF1a__YP_009010969__Porcine_astrovirus_5__1093928__D1-101
D2 high residues 748-871
PDB
Domain cluster: rep: ORF1a__YP_009052460__Feline_astrovirus_D1__1538452__D722-831
D3 medium residues 436-450_511-604
PDB
Domain cluster: rep: ORF1a__YP_009047079__Human_astrovirus_BF34__1518575__D522-618
CATH (36)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3k6yA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.87 65.0 6.59e-01 77.1% 100.0%
3otpA01 2.40.10.120 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.86 78.0 6.16e-01 95.4% 96.6%
5hmaA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.84 64.0 6.61e-01 78.9% 100.0%
4ri0A01 2.40.10.120 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.83 74.0 5.98e-01 95.4% 95.5%
4ic5A02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.83 62.0 6.40e-01 78.0% 97.1%
2aq6A00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.78 54.0 4.88e-01 70.6% 93.7%
2i02A00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.77 54.0 4.92e-01 71.6% 93.6%
3ec6A00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.77 53.0 5.03e-01 70.6% 96.9%
2iabA01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.77 55.0 4.96e-01 73.4% 94.4%
3u5wA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.76 53.0 5.01e-01 70.6% 93.7%
2fg9A01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.76 52.0 4.59e-01 70.6% 87.4%
5jv4A00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.76 52.0 4.75e-01 70.6% 97.2%
1wczA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.76 68.0 6.67e-01 99.1% 89.6%
2fhqA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.75 52.0 4.88e-01 71.6% 97.8%
5yjlD01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.75 54.0 4.89e-01 73.4% 91.5%
2i51B00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.75 55.0 4.49e-01 75.2% 93.7%
2hq9B00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.75 52.0 4.77e-01 70.6% 94.2%
1wv4B00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.74 54.0 4.79e-01 75.2% 87.7%
5bncB01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.74 53.0 4.73e-01 73.4% 92.6%
1rfeA01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.74 51.0 4.73e-01 70.6% 89.7%
2htiA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.74 51.0 4.86e-01 70.6% 95.2%
3gasB02 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.74 54.0 4.61e-01 75.2% 88.7%
2ptfA01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.73 52.0 4.69e-01 73.4% 93.2%
1agjA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.73 63.0 5.84e-01 90.8% 83.6%
4ybnB00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.73 53.0 4.21e-01 74.3% 69.3%
1p3cA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.73 63.0 6.42e-01 91.7% 93.3%
1zyoA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.73 63.0 6.51e-01 97.2% 98.0%
1ylnA01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.72 50.0 4.93e-01 70.6% 91.2%
2hhzA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.71 51.0 4.71e-01 74.3% 95.7%
3dnhA01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.69 54.0 4.83e-01 82.6% 96.7%
3l6pA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.67 56.0 5.74e-01 89.0% 98.1%
3h96C00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.60 51.0 4.75e-01 92.7% 100.0%
3bbaA00 3.90.70.50 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Streptopain (SpeB) 0.59 41.0 3.14e-01 72.5% 46.3%
2gpjA01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.56 37.0 3.86e-01 94.5% 74.0%
4qqgG00 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.53 31.0 3.64e-01 83.5% 86.1%
3ntkA02 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.50 31.0 3.55e-01 91.7% 85.0%
ECOD (56)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
134018 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.89 81.0 6.89e-01 94.5% 99.4%
3448847 1.1.17.3 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.87 80.0 5.75e-01 96.3% 98.2%
5063188 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.87 78.0 6.05e-01 94.5% 91.2%
4028981 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.85 77.0 5.94e-01 95.4% 95.9%
3447254 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.84 79.0 6.10e-01 100.0% 98.6%
3425181 1.1.17.3 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.84 79.0 6.00e-01 100.0% 95.7%
3672433 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.83 69.0 4.97e-01 88.1% 80.3%
5072499 1.1.17.3 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.83 75.0 6.06e-01 97.2% 96.5%
3449628 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.83 68.0 6.66e-01 86.2% 90.4%
3437290 1.1.17.3 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.82 76.0 5.95e-01 100.0% 98.6%
3447771 1.1.17.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.80 72.0 5.48e-01 96.3% 96.7%
3377696 1.1.17.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.80 71.0 5.74e-01 95.4% 99.5%
1308507 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.80 72.0 5.90e-01 96.3% 94.7%
4928817 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.79 55.0 4.87e-01 71.6% 94.0%
5049939 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.79 54.0 4.77e-01 70.6% 84.4%
4999005 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.78 54.0 4.68e-01 71.6% 94.5%
4928784 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.78 54.0 4.28e-01 70.6% 73.7%
3279487 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.77 53.0 4.89e-01 70.6% 95.0%
3953421 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.77 53.0 4.86e-01 70.6% 87.9%
60 1.1.5.36 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyrid_ox_like 0.77 54.0 4.92e-01 71.6% 93.6%
2095485 1.1.5.38 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Peptidase_C107 0.77 67.0 5.29e-01 91.7% 91.8%
3283546 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.77 56.0 5.03e-01 74.3% 93.0%
5018015 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.77 53.0 4.78e-01 70.6% 95.2%
3164508 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.77 55.0 4.66e-01 73.4% 87.6%
2472950 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.76 69.0 5.65e-01 95.4% 98.9%
3388199 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.76 54.0 4.63e-01 73.4% 86.5%
66 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.76 52.0 4.65e-01 70.6% 90.8%
5071939 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.76 52.0 4.58e-01 70.6% 94.3%
144904 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.76 52.0 5.00e-01 70.6% 93.6%
5062740 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.76 53.0 4.38e-01 71.6% 77.3%
4987534 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.76 53.0 4.74e-01 71.6% 94.0%
4961061 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.76 52.0 4.61e-01 70.6% 91.0%
4960378 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.76 52.0 4.71e-01 70.6% 92.4%
4125768 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.76 52.0 4.65e-01 70.6% 91.3%
3469033 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.75 70.0 5.26e-01 100.0% 92.4%
4157289 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.75 53.0 4.46e-01 71.6% 82.3%
3288278 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.75 52.0 4.79e-01 70.6% 88.9%
4958701 1.1.5.17 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › DUF447_N 0.74 51.0 4.77e-01 70.6% 88.1%
3279818 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.74 54.0 4.89e-01 75.2% 90.3%
3283851 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.74 53.0 4.94e-01 73.4% 97.7%
3248403 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.73 62.0 5.73e-01 89.9% 83.7%
57 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.73 52.0 4.52e-01 73.4% 87.5%
1695162 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.72 54.0 4.24e-01 77.1% 71.0%
3290558 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.72 52.0 4.64e-01 75.2% 92.3%
5036486 1.1.5.11 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › UbiD 0.71 56.0 4.45e-01 82.6% 85.7%
5018190 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.70 54.0 4.67e-01 79.8% 93.1%
4295310 1.1.5.15 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › F420H2_quin_red 0.64 54.0 4.85e-01 89.0% 89.3%
3958190 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.63 55.0 5.01e-01 92.7% 95.7%
4931814 1.1.5.15 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › F420H2_quin_red 0.63 53.0 4.81e-01 89.0% 99.3%
3280574 1.1.5.15 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › F420H2_quin_red 0.62 53.0 4.90e-01 92.7% 95.7%
3291237 1.1.5.15 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › F420H2_quin_red 0.60 50.0 4.87e-01 89.0% 95.0%
3283665 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.58 49.0 4.21e-01 90.8% 94.5%
3900957 220.1.1.1 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.53 37.0 3.53e-01 71.6% 78.5%
4332533 220.1.1.12 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › Myosin_TH1 0.53 37.0 2.95e-01 71.6% 61.4%
3765367 220.1.1.1 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.52 36.0 3.28e-01 71.6% 76.7%
3621943 220.1.1.1 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.50 36.0 3.40e-01 73.4% 83.1%
D4 medium residues 451-510
PDB
Domain cluster: rep: ORF1a__YP_009162618__Dromedary_astrovirus__1662272__D428-481