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ORF1a

Euk-Vir

Dromedary_astrovirus

ORF1a__YP_009162618__Dromedary_astrovirus__1662272

Identity

Accession:
YP_009162618 ↗
Protein ID:
ORF1a
Kingdom:
euk

Quality

63.6 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 29-100
PDB
D2 high residues 733-804
PDB
D4 medium residues 409-427_482-566
PDB
D5 medium residues 428-481
PDB
Domain cluster: representative
CATH (56)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2w5eA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.96 80.0 7.41e-01 88.9% 72.3%
3k6yA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.82 75.0 6.18e-01 100.0% 58.7%
3nziA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.81 73.0 5.79e-01 100.0% 52.8%
5y2dA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.80 73.0 5.54e-01 100.0% 46.7%
4tkoB01 2.40.30.170 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Efflux pump adaptor protein, beta barrel domain 0.74 65.0 5.48e-01 100.0% 73.9%
4m9fA00 2.40.10.120 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.74 54.0 3.65e-01 87.0% 21.0%
4q63A00 2.40.10.430 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.72 63.0 5.29e-01 100.0% 66.7%
1ep3B01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.72 61.0 5.11e-01 100.0% 75.8%
2dpyA00 3.40.50.12240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.71 62.0 3.68e-01 100.0% 13.0%
8gz3B01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.71 62.0 5.21e-01 100.0% 75.3%
3su0A01 2.40.10.120 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.70 55.0 4.36e-01 100.0% 42.0%
2piaA01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.69 60.0 4.91e-01 100.0% 73.1%
3dtdD00 2.60.40.1880 Mainly Beta › Sandwich › Immunoglobulin-like › Invasion associated locus B (IalB) protein 0.68 58.0 4.34e-01 100.0% 65.5%
1krhA02 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.68 58.0 4.88e-01 100.0% 74.2%
2ynaA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.68 58.0 5.04e-01 100.0% 80.7%
2gpjA01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.68 58.0 4.81e-01 100.0% 75.0%
4rt0A00 2.40.10.220 Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains 0.67 57.0 4.67e-01 100.0% 64.2%
6baoA02 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.66 51.0 3.88e-01 88.9% 69.9%
2wv9A01 2.40.10.120 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.66 53.0 3.74e-01 90.7% 32.6%
1qfjA01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.65 54.0 4.73e-01 100.0% 75.8%
5yzzC00 2.40.330.10 Mainly Beta › Beta Barrel › At1g16640 B3 domain › DNA-binding pseudobarrel domain 0.65 53.0 4.39e-01 100.0% 67.6%
2xzlA02 2.40.30.230 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.64 55.0 4.91e-01 100.0% 79.7%
4i86A00 2.40.10.220 Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains 0.64 53.0 4.46e-01 100.0% 66.7%
5i7pA02 2.40.10.330 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.63 48.0 5.05e-01 85.2% 100.0%
1u9tA01 3.40.1570.10 Alpha Beta › 3-Layer(aba) Sandwich › Heme iron utilization protein-like fold › HemS/ChuS/ChuX like domains 0.63 48.0 3.55e-01 87.0% 89.9%
2f1lA01 2.40.30.60 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › RimM 0.63 54.0 4.65e-01 100.0% 74.2%
2kr7A02 2.40.10.330 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.63 52.0 5.14e-01 92.6% 87.7%
2oolA01 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.63 47.0 3.95e-01 87.0% 88.8%
3zugB02 2.40.30.30 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Riboflavin kinase-like 0.63 51.0 3.97e-01 100.0% 58.5%
3okxB00 2.40.30.70 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › YaeB-like 0.61 50.0 3.80e-01 100.0% 71.1%
3oc5A02 2.60.40.3240 Mainly Beta › Sandwich › Immunoglobulin-like › Vibrio cholerae toxin co-regulated pilus biosynthesis protein F, C-terminal domain 0.60 50.0 3.85e-01 100.0% 64.5%
2xtsA02 2.60.40.650 Mainly Beta › Sandwich › Immunoglobulin-like › 0.60 52.0 3.97e-01 100.0% 86.2%
1ywuA00 2.40.10.220 Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains 0.58 40.0 3.12e-01 81.5% 31.2%
4kktA01 2.40.420.20 Mainly Beta › Beta Barrel › conserved putative lor/sdh protein from methanococcus maripaludis s2 fold › 0.58 48.0 4.13e-01 100.0% 59.4%
3lnnA01 2.40.420.20 Mainly Beta › Beta Barrel › conserved putative lor/sdh protein from methanococcus maripaludis s2 fold › 0.58 48.0 4.22e-01 100.0% 69.2%
3sz6A00 2.60.40.1850 Mainly Beta › Sandwich › Immunoglobulin-like › 0.58 49.0 3.94e-01 100.0% 75.9%
2jheA02 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.58 44.0 3.67e-01 88.9% 87.0%
4mypA00 2.60.40.1850 Mainly Beta › Sandwich › Immunoglobulin-like › 0.58 48.0 3.86e-01 100.0% 74.4%
3c8cB01 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.58 46.0 3.61e-01 92.6% 66.1%
2wj6A01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.56 38.0 2.63e-01 70.4% 38.2%
3zn6A02 2.60.40.3410 Mainly Beta › Sandwich › Immunoglobulin-like › 0.56 46.0 4.06e-01 100.0% 81.6%
2basA03 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.56 43.0 3.56e-01 92.6% 88.8%
1bwzA01 3.10.310.10 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 0.56 43.0 3.28e-01 85.2% 86.6%
2va0A00 3.30.450.160 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.55 40.0 3.49e-01 87.0% 73.7%
3askA02 2.30.30.1150 Mainly Beta › Roll › SH3 type barrels. › 0.54 36.0 2.82e-01 74.1% 35.8%
1ltmA02 1.10.530.10 Mainly Alpha › Orthogonal Bundle › Lysozyme › 0.54 39.0 2.91e-01 85.2% 35.8%
2bolA03 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.54 41.0 3.62e-01 92.6% 92.5%
2zylA01 2.102.10.10 Mainly Beta › 3-layer Sandwich › Rieske Iron-sulfur Protein › Rieske [2Fe-2S] iron-sulphur domain 0.54 41.0 3.21e-01 88.9% 82.2%
4gaaA01 2.60.40.1730 Mainly Beta › Sandwich › Immunoglobulin-like › tricorn interacting facor f3 domain 0.53 42.0 3.05e-01 100.0% 43.0%
4bzyA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 41.0 3.45e-01 100.0% 53.1%
2l3rA02 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.51 34.0 3.25e-01 72.2% 74.0%
2ofqA01 2.60.40.2500 Mainly Beta › Sandwich › Immunoglobulin-like › 0.51 41.0 3.68e-01 100.0% 78.7%
2jhnA01 3.30.310.20 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › DNA-3-methyladenine glycosylase AlkA, N-terminal domain 0.51 39.0 3.26e-01 92.6% 59.3%
4b7lA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.51 42.0 3.59e-01 100.0% 88.0%
1vprA03 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.50 40.0 3.04e-01 96.3% 46.5%
2xq0A01 2.60.40.1730 Mainly Beta › Sandwich › Immunoglobulin-like › tricorn interacting facor f3 domain 0.50 40.0 3.00e-01 100.0% 44.1%
ECOD (73)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
134018 1.1.5.33 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.95 87.0 5.91e-01 100.0% 32.1%
4119987 1.1.5.0 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.81 73.0 4.76e-01 100.0% 27.1%
3672433 1.1.5.33 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.81 73.0 4.53e-01 100.0% 23.1%
4973665 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.74 60.0 5.24e-01 92.6% 74.1%
4402716 1.1.7.17 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › ATP-synt_ab_N 0.74 65.0 5.61e-01 100.0% 64.7%
4125814 1.1.7.17 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › ATP-synt_ab_N 0.73 64.0 5.76e-01 100.0% 70.7%
4061526 1.1.7.7 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_6 0.73 63.0 5.21e-01 100.0% 75.0%
3967745 1.1.7.17 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › ATP-synt_ab_N 0.73 66.0 5.86e-01 100.0% 74.7%
4947671 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.72 62.0 5.51e-01 100.0% 83.7%
5069408 1.1.7.7 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_6 0.71 62.0 5.26e-01 100.0% 77.8%
4890345 1.1.7.17 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › ATP-synt_ab_N 0.70 62.0 5.34e-01 100.0% 65.9%
5041917 1.1.7.8 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Ribosomal_L35Ae 0.70 60.0 5.17e-01 100.0% 76.7%
3976133 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.70 60.0 5.06e-01 100.0% 69.5%
4944696 1.1.7.138 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › NAD_binding_1 0.70 59.0 4.94e-01 100.0% 77.0%
5010302 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.70 59.0 5.20e-01 100.0% 74.1%
3461468 1.1.11.1 beta barrels › cradle loop barrel › RIFT-related › Type II restriction endonuclease effector domain › B3 0.69 58.0 4.68e-01 100.0% 63.5%
4366786 1.1.7.7 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_6 0.69 59.0 4.78e-01 100.0% 68.2%
3930882 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.68 58.0 4.94e-01 100.0% 75.8%
3402635 1.1.7.7 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_6 0.68 58.0 4.44e-01 100.0% 63.7%
4553723 1.1.7.11 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RimM 0.67 57.0 4.86e-01 100.0% 67.4%
3523254 10.2.1.0 beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) 0.67 55.0 3.91e-01 96.3% 58.9%
4214180 1.1.7.11 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RimM 0.67 56.0 4.79e-01 100.0% 67.4%
4381495 1.1.7.11 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RimM 0.66 56.0 4.85e-01 100.0% 68.9%
4997059 4.1.1.139 beta barrels › SH3 › SH3 › SH3 › IF5A-like_N 0.66 45.0 4.16e-01 74.1% 70.7%
4083333 1.1.7.11 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RimM 0.66 55.0 4.72e-01 100.0% 66.3%
3345450 1.1.11.1 beta barrels › cradle loop barrel › RIFT-related › Type II restriction endonuclease effector domain › B3 0.66 55.0 4.39e-01 100.0% 60.0%
5006332 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.66 51.0 4.51e-01 88.9% 98.8%
4138546 1.1.7.11 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RimM 0.65 55.0 4.79e-01 100.0% 71.1%
4098005 1.1.7.11 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RimM 0.65 54.0 4.74e-01 100.0% 77.8%
4995368 12.5.1.0 beta sandwiches › Glycosyl hydrolase domain-like › ZU5/Nup98-C/GAIN-B autoproteolytic domain-related › ZU5/Nup98-C/GAIN-B autoproteolytic domain-related 0.65 57.0 4.29e-01 100.0% 71.9%
4599558 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.65 53.0 4.60e-01 94.4% 87.8%
3176963 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.65 49.0 3.82e-01 85.2% 98.5%
3617111 4.1.1.9 beta barrels › SH3 › SH3 › SH3 › TUDOR 0.65 45.0 3.84e-01 74.1% 45.6%
3966626 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.64 55.0 4.75e-01 100.0% 73.3%
4592324 1.1.7.11 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RimM 0.64 54.0 4.68e-01 100.0% 77.8%
3596793 1.1.5.0 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.64 51.0 3.27e-01 92.6% 18.6%
4438946 1.1.7.11 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RimM 0.64 53.0 4.73e-01 100.0% 74.1%
4682440 1.1.7.11 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RimM 0.64 54.0 4.59e-01 100.0% 65.3%
4220217 1.1.7.11 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RimM 0.64 54.0 4.61e-01 100.0% 69.5%
4391995 1.1.7.11 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RimM 0.64 52.0 4.66e-01 100.0% 78.8%
3171919 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.64 48.0 4.21e-01 83.3% 100.0%
4066771 1.1.7.11 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RimM 0.64 52.0 4.52e-01 100.0% 69.5%
5048423 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.63 49.0 4.04e-01 92.6% 84.3%
3277070 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.63 53.0 4.77e-01 100.0% 71.2%
4208972 1.1.7.11 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RimM 0.63 52.0 4.40e-01 100.0% 68.0%
2898325 271.1.1.2 beta barrels › GFP-like › GFP-like › GFP-like 0.62 46.0 2.90e-01 81.5% 19.7%
4660635 4000.1.1.1 a+b two layers › Escherichia coli HybE › Escherichia coli HybE › Escherichia coli HybE › NiFe-hyd_HybE 0.62 52.0 4.03e-01 100.0% 54.8%
4163756 1.1.7.11 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RimM 0.62 50.0 4.37e-01 100.0% 69.5%
4381868 1.1.7.11 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RimM 0.61 52.0 4.50e-01 100.0% 68.9%
3261993 11.1.1.843 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › DUF7034 0.61 51.0 4.13e-01 100.0% 93.0%
4405079 1.1.7.11 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RimM 0.61 50.0 4.35e-01 100.0% 66.3%
5008603 223.1.1.2 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS 0.61 47.0 3.34e-01 88.9% 55.3%
4184401 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.61 47.0 3.51e-01 90.7% 54.4%
3930311 220.1.1.176 beta barrels › PH domain-like › PH domain-like › PH domain-like › DUF7778 0.61 46.0 3.66e-01 85.2% 71.7%
4237254 1.1.9.0 beta barrels › cradle loop barrel › RIFT-related › PUA domain 0.61 49.0 4.31e-01 92.6% 69.4%
3794026 11.1.1.12 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Filamin 0.61 49.0 4.34e-01 94.4% 84.7%
4295277 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.60 46.0 3.47e-01 88.9% 44.0%
3267250 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.59 46.0 4.23e-01 94.4% 87.5%
4008034 223.1.1.113 a+b three layers › Profilin-like › sensor domains › sensor domains › PF30408 0.59 46.0 3.35e-01 90.7% 40.6%
3956757 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.59 45.0 3.87e-01 88.9% 69.5%
3271989 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.59 48.0 4.21e-01 100.0% 93.3%
2771756 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.57 43.0 3.99e-01 87.0% 90.5%
4459946 223.1.1.6 a+b three layers › Profilin-like › sensor domains › sensor domains › dCache_1 0.57 42.0 2.84e-01 87.0% 32.2%
4047545 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.56 44.0 3.32e-01 92.6% 56.1%
4944566 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.55 42.0 3.53e-01 92.6% 83.5%
3791256 319.1.1.1 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 0.55 43.0 3.53e-01 90.7% 75.5%
3692189 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.55 41.0 3.28e-01 90.7% 52.6%
4399650 223.1.1.59 a+b three layers › Profilin-like › sensor domains › sensor domains › ArlS_N 0.54 43.0 3.09e-01 92.6% 37.1%
4928263 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.53 40.0 3.33e-01 88.9% 85.5%
4937366 4312.1.1.3 a+b two layers › RelE-like › RelE-like › RelE-like › ParE_toxin 0.52 39.0 3.46e-01 90.7% 83.2%
4928046 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.51 39.0 3.22e-01 92.6% 63.3%
3820521 2004.1.1.1 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.51 39.0 2.57e-01 92.6% 21.3%
5073525 223.2.1.5 a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7 0.50 39.0 3.14e-01 90.7% 76.0%