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ORF22
Euk-VirIctalurid_herpesvirus_1
ORF22__NP_041113__Ictalurid_herpesvirus_1__10401
Identity
- Accession:
- NP_041113 ↗
- Protein ID:
- ORF22
- Kingdom:
- euk
Quality
51.1
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Alloherpesviridae›
Ictavirus›
Ictalurid_herpesvirus_1
TaxID: 10401
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 447-512
D2
medium
residues 525-594
D3
medium
residues 699-763
Domain cluster:
representative
CATH (83)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3qo8A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.93 | 88.0 | 7.26e-01 | 100.0% | 64.2% |
| 3sjqC00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.93 | 83.0 | 7.69e-01 | 100.0% | 77.5% |
| 4ijjB00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.92 | 87.0 | 6.70e-01 | 100.0% | 50.8% |
| 2gtsA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.92 | 85.0 | 8.01e-01 | 100.0% | 85.7% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.92 | 85.0 | 5.92e-01 | 100.0% | 51.6% |
| 6iknD01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.92 | 85.0 | 5.40e-01 | 100.0% | 24.0% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.91 | 84.0 | 5.55e-01 | 100.0% | 29.5% |
| 1ykeD00 | 6.10.280.10 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator complex, subunit Med21 | 0.90 | 84.0 | 6.82e-01 | 100.0% | 63.7% |
| 3rklA00 | 6.10.140.1640 | Special › Helix non-globular › Helix Hairpins › | 0.90 | 74.0 | 6.87e-01 | 98.5% | 71.2% |
| 2wmmA01 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.89 | 64.0 | 7.30e-01 | 81.5% | 100.0% |
| 1jogA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.89 | 80.0 | 6.05e-01 | 100.0% | 45.2% |
| 3fppA03 | 6.10.140.1990 | Special › Helix non-globular › Helix Hairpins › | 0.89 | 82.0 | 7.30e-01 | 100.0% | 72.7% |
| 2rd0B00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.89 | 82.0 | 6.27e-01 | 100.0% | 77.7% |
| 3fd9A03 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.89 | 82.0 | 7.86e-01 | 100.0% | 89.0% |
| 2dq0A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.89 | 81.0 | 6.77e-01 | 100.0% | 66.4% |
| 6h9xA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.89 | 83.0 | 6.98e-01 | 100.0% | 68.6% |
| 1u7lA02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.88 | 80.0 | 5.62e-01 | 96.9% | 93.4% |
| 3n5lA03 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.88 | 73.0 | 7.70e-01 | 93.8% | 100.0% |
| 2js5A00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.88 | 76.0 | 7.37e-01 | 98.5% | 84.5% |
| 1fs0G02 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.88 | 80.0 | 7.06e-01 | 96.9% | 89.9% |
| 7ymiZ01 | 1.10.287.740 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre | 0.88 | 70.0 | 7.41e-01 | 84.6% | 100.0% |
| 4abmD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.87 | 76.0 | 7.21e-01 | 95.4% | 89.6% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.87 | 70.0 | 7.05e-01 | 100.0% | 85.9% |
| 4mycA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.87 | 75.0 | 4.66e-01 | 100.0% | 18.3% |
| 1ku9A02 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.87 | 75.0 | 7.55e-01 | 90.8% | 96.9% |
| 3u0cA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.87 | 80.0 | 5.97e-01 | 100.0% | 65.6% |
| 3jcuZ00 | 1.10.287.740 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre | 0.86 | 73.0 | 7.57e-01 | 90.8% | 100.0% |
| 3r84A00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.86 | 79.0 | 7.28e-01 | 100.0% | 80.2% |
| 3l1nA01 | 6.10.140.790 | Special › Helix non-globular › Helix Hairpins › | 0.86 | 64.0 | 7.12e-01 | 83.1% | 100.0% |
| 3layF00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.85 | 74.0 | 6.98e-01 | 100.0% | 79.5% |
| 3nrxA00 | 1.20.58.1520 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.85 | 67.0 | 5.36e-01 | 100.0% | 44.7% |
| 3pltA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.85 | 78.0 | 5.31e-01 | 100.0% | 34.6% |
| 3lssA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.85 | 76.0 | 6.33e-01 | 100.0% | 64.3% |
| 4nsmA00 | 6.10.250.2770 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.84 | 72.0 | 7.00e-01 | 100.0% | 84.5% |
| 2b5uA02 | 1.10.287.620 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins | 0.84 | 78.0 | 5.68e-01 | 100.0% | 40.4% |
| 1yg2A02 | 6.10.140.190 | Special › Helix non-globular › Helix Hairpins › | 0.84 | 77.0 | 6.85e-01 | 100.0% | 72.2% |
| 1y1uA01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.83 | 74.0 | 5.24e-01 | 100.0% | 49.7% |
| 1vx7301 | 1.10.287.310 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.83 | 72.0 | 6.93e-01 | 95.4% | 83.8% |
| 1wleA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.82 | 75.0 | 6.16e-01 | 100.0% | 57.9% |
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.81 | 72.0 | 6.93e-01 | 100.0% | 89.3% |
| 2ch7A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.81 | 72.0 | 4.61e-01 | 100.0% | 96.8% |
| 1gaxA05 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.81 | 67.0 | 6.43e-01 | 100.0% | 79.5% |
| 2cazD00 | 6.10.140.820 | Special › Helix non-globular › Helix Hairpins › | 0.81 | 63.0 | 6.49e-01 | 100.0% | 90.0% |
| 1ucuA01 | 6.10.280.190 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.80 | 72.0 | 7.11e-01 | 98.5% | 97.1% |
| 1aj3A00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.80 | 66.0 | 5.77e-01 | 90.8% | 60.2% |
| 1urfA00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.80 | 71.0 | 6.59e-01 | 98.5% | 95.1% |
| 2efkA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.80 | 70.0 | 4.66e-01 | 100.0% | 26.0% |
| 1u5pA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.79 | 71.0 | 5.95e-01 | 100.0% | 60.2% |
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.79 | 67.0 | 5.70e-01 | 93.8% | 69.2% |
| 2oezA02 | 1.10.3900.10 | Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like | 0.78 | 64.0 | 4.65e-01 | 87.7% | 35.0% |
| 7zd5C01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.77 | 69.0 | 4.38e-01 | 100.0% | 21.1% |
| 1b5lA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.77 | 60.0 | 4.56e-01 | 84.6% | 100.0% |
| 6tqfA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.77 | 67.0 | 4.11e-01 | 100.0% | 16.9% |
| 1avoB00 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.77 | 67.0 | 5.26e-01 | 100.0% | 48.6% |
| 3ehfD01 | 1.20.5.1930 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.77 | 60.0 | 6.16e-01 | 87.7% | 92.1% |
| 2gl2B00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.76 | 67.0 | 5.67e-01 | 100.0% | 58.7% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.76 | 64.0 | 5.29e-01 | 93.8% | 52.6% |
| 3okqA00 | 1.20.58.1540 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain | 0.76 | 66.0 | 5.38e-01 | 100.0% | 52.8% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.75 | 66.0 | 6.24e-01 | 100.0% | 91.0% |
| 3onjA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.75 | 63.0 | 5.61e-01 | 98.5% | 63.9% |
| 2bduA02 | 1.10.150.340 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Pyrimidine 5'-nucleotidase (UMPH-1), N-terminal domain | 0.75 | 54.0 | 5.22e-01 | 80.0% | 67.6% |
| 1qv9A02 | 6.10.140.120 | Special › Helix non-globular › Helix Hairpins › | 0.75 | 63.0 | 5.48e-01 | 96.9% | 60.2% |
| 1hciA04 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.75 | 66.0 | 5.51e-01 | 100.0% | 57.0% |
| 5b1oA00 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.75 | 55.0 | 5.56e-01 | 80.0% | 81.5% |
| 4nb5B02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.75 | 62.0 | 6.31e-01 | 100.0% | 95.3% |
| 1jadA00 | 1.20.1230.10 | Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain | 0.75 | 69.0 | 4.55e-01 | 100.0% | 80.6% |
| 4nv0A02 | 1.10.150.340 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Pyrimidine 5'-nucleotidase (UMPH-1), N-terminal domain | 0.74 | 53.0 | 4.98e-01 | 80.0% | 61.0% |
| 2yf4F00 | 1.10.3420.10 | Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain | 0.73 | 65.0 | 4.97e-01 | 96.9% | 76.9% |
| 3rq9A00 | 1.10.287.2500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.73 | 61.0 | 5.76e-01 | 95.4% | 78.2% |
| 2kw6A00 | 6.10.140.1300 | Special › Helix non-globular › Helix Hairpins › | 0.73 | 57.0 | 5.75e-01 | 89.2% | 84.6% |
| 6vq6G02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.72 | 61.0 | 4.46e-01 | 95.4% | 97.3% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 61.0 | 5.33e-01 | 100.0% | 61.7% |
| 5dkoA02 | 1.10.3900.10 | Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like | 0.72 | 58.0 | 4.27e-01 | 87.7% | 34.1% |
| 3r84B00 | 6.10.280.160 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 | 0.72 | 63.0 | 5.94e-01 | 100.0% | 82.5% |
| 1tj7A01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.72 | 52.0 | 4.42e-01 | 76.9% | 48.6% |
| 1m62A00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.71 | 54.0 | 4.94e-01 | 83.1% | 66.7% |
| 2wyhB04 | 1.20.1270.50 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain | 0.71 | 62.0 | 5.36e-01 | 100.0% | 63.4% |
| 1f45B00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.71 | 61.0 | 4.87e-01 | 98.5% | 59.4% |
| 3t5vA00 | 1.25.40.990 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.70 | 61.0 | 3.87e-01 | 95.4% | 71.6% |
| 1s5jA04 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.69 | 54.0 | 5.55e-01 | 92.3% | 91.8% |
| 1ykhA00 | 6.10.140.200 | Special › Helix non-globular › Helix Hairpins › | 0.69 | 58.0 | 5.28e-01 | 100.0% | 68.4% |
| 1rfyB00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.69 | 59.0 | 5.40e-01 | 96.9% | 71.6% |
| 2b3tB01 | 6.10.140.1980 | Special › Helix non-globular › Helix Hairpins › | 0.61 | 47.0 | 4.77e-01 | 87.7% | 86.2% |
ECOD (79)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3470680 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.96 | 91.0 | 5.36e-01 | 100.0% | 77.6% |
| 3336964 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.95 | 91.0 | 5.79e-01 | 100.0% | 25.5% |
| 3780286 | 244.1.1.6 ↗ | a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C › Amino_oxidase | 0.95 | 90.0 | 5.07e-01 | 100.0% | 14.0% |
| 3495507 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.94 | 90.0 | 6.38e-01 | 100.0% | 39.4% |
| 3919840 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.94 | 89.0 | 5.89e-01 | 100.0% | 45.5% |
| 3927738 | 632.8.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 | 0.94 | 89.0 | 7.62e-01 | 100.0% | 68.4% |
| 3592972 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.94 | 88.0 | 6.04e-01 | 100.0% | 44.1% |
| 3262220 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.94 | 88.0 | 5.57e-01 | 100.0% | 23.2% |
| 3403130 | 4323.1.1.1 ↗ | alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › V_ATPase_I | 0.93 | 88.0 | 6.30e-01 | 100.0% | 41.2% |
| 4000290 | 192.29.1.188 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › F_actin_bind | 0.93 | 89.0 | 6.80e-01 | 100.0% | 50.8% |
| 3181110 | 5086.1.1.110 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HisKA | 0.93 | 87.0 | 7.52e-01 | 100.0% | 68.4% |
| 4225190 | 4207.1.2.29 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region › Med4 | 0.93 | 87.0 | 6.64e-01 | 100.0% | 48.1% |
| 4500653 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.92 | 86.0 | 6.37e-01 | 100.0% | 52.7% |
| 3906191 | 4323.1.1.1 ↗ | alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › V_ATPase_I | 0.92 | 87.0 | 6.33e-01 | 100.0% | 41.9% |
| 3417475 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.92 | 87.0 | 5.12e-01 | 100.0% | 15.7% |
| 1879027 | 244.1.1.6 ↗ | a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C › Amino_oxidase | 0.92 | 87.0 | 5.18e-01 | 100.0% | 17.1% |
| 5066104 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.92 | 87.0 | 4.93e-01 | 100.0% | 37.2% |
| 5040840 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.91 | 85.0 | 4.70e-01 | 100.0% | 33.3% |
| 3240634 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.91 | 85.0 | 6.22e-01 | 100.0% | 80.6% |
| 4396574 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.91 | 85.0 | 6.12e-01 | 100.0% | 39.6% |
| 3925257 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.91 | 85.0 | 5.95e-01 | 100.0% | 36.1% |
| 4946898 | 375.1.9.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Zinc-nucleated domain of serine integrase | 0.91 | 82.0 | 7.80e-01 | 96.9% | 90.7% |
| 3839497 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.91 | 84.0 | 7.57e-01 | 100.0% | 77.6% |
| 3725615 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.90 | 74.0 | 6.84e-01 | 86.2% | 70.0% |
| 4960061 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.90 | 83.0 | 7.06e-01 | 98.5% | 71.0% |
| 4238208 | 2004.1.1.481 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_29 | 0.90 | 85.0 | 5.04e-01 | 100.0% | 16.0% |
| 3804036 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.90 | 83.0 | 6.70e-01 | 100.0% | 68.7% |
| 4177674 | 4992.1.1.23 ↗ | extended segments › RelB-like › RelB-like › RelB-like › Seryl_tRNA_N | 0.90 | 83.0 | 6.84e-01 | 100.0% | 65.5% |
| 3562849 | 148.1.3.254 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › KIF21A_4th | 0.89 | 82.0 | 5.48e-01 | 100.0% | 30.0% |
| 3872946 | 601.19.1.55 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › PF28139 | 0.89 | 84.0 | 4.95e-01 | 100.0% | 15.9% |
| 3840952 | 601.19.1.39 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › LIN9_C | 0.89 | 82.0 | 7.82e-01 | 100.0% | 94.7% |
| 3693258 | 604.7.1.1 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA | 0.89 | 82.0 | 6.73e-01 | 100.0% | 60.0% |
| 3782160 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.89 | 83.0 | 5.17e-01 | 100.0% | 21.3% |
| 4507542 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.89 | 80.0 | 7.03e-01 | 100.0% | 68.9% |
| 4493879 | 4992.1.1.23 ↗ | extended segments › RelB-like › RelB-like › RelB-like › Seryl_tRNA_N | 0.88 | 82.0 | 6.73e-01 | 100.0% | 65.5% |
| 3477418 | 4992.1.1.12 ↗ | extended segments › RelB-like › RelB-like › RelB-like › LIN9_C | 0.88 | 82.0 | 7.10e-01 | 100.0% | 75.8% |
| 4024396 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.88 | 81.0 | 6.23e-01 | 100.0% | 54.1% |
| 3298167 | 5086.1.1.62 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › XH | 0.88 | 81.0 | 6.17e-01 | 100.0% | 46.4% |
| 3832902 | 3684.1.1.41 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PF27018 | 0.88 | 75.0 | 5.65e-01 | 92.3% | 41.4% |
| 4324499 | 3755.1.1.3 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › SPAM | 0.87 | 79.0 | 6.00e-01 | 100.0% | 57.2% |
| 3732397 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.87 | 79.0 | 6.39e-01 | 100.0% | 60.0% |
| 3541678 | 101.1.1.117 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › CHDCT2 | 0.87 | 78.0 | 6.79e-01 | 100.0% | 66.3% |
| 3754639 | 150.5.1.106 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › LIN9_C | 0.87 | 79.0 | 7.20e-01 | 100.0% | 84.7% |
| 3942242 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.87 | 79.0 | 6.06e-01 | 100.0% | 87.1% |
| 3992995 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.87 | 78.0 | 6.67e-01 | 100.0% | 66.0% |
| 4937604 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.86 | 80.0 | 6.48e-01 | 100.0% | 56.5% |
| 3687766 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.86 | 81.0 | 5.37e-01 | 100.0% | 28.9% |
| 3231045 | 101.1.1.117 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › CHDCT2 | 0.86 | 78.0 | 6.55e-01 | 100.0% | 61.0% |
| 3623410 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.85 | 78.0 | 4.50e-01 | 100.0% | 13.5% |
| 3699444 | 3755.3.1.6 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Flagellar_rod | 0.85 | 78.0 | 5.25e-01 | 100.0% | 29.8% |
| 4660205 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.85 | 76.0 | 5.96e-01 | 100.0% | 68.9% |
| 3326073 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.85 | 77.0 | 6.39e-01 | 100.0% | 59.1% |
| 3942983 | 101.1.4.8 ↗ | alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › Phage_CP76 | 0.84 | 76.0 | 5.69e-01 | 100.0% | 42.7% |
| 5017743 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.84 | 72.0 | 6.57e-01 | 93.8% | 78.8% |
| 4297833 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.83 | 72.0 | 6.45e-01 | 96.9% | 68.9% |
| 4043561 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.83 | 74.0 | 6.08e-01 | 95.4% | 73.6% |
| 3712411 | 3939.1.1.0 ↗ | alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain | 0.83 | 76.0 | 5.01e-01 | 100.0% | 26.0% |
| 3542369 | 246.2.1.1 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos | 0.83 | 76.0 | 4.54e-01 | 100.0% | 14.9% |
| 3229124 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.83 | 73.0 | 5.53e-01 | 95.4% | 42.8% |
| 4968656 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.83 | 76.0 | 4.68e-01 | 100.0% | 90.6% |
| 4206858 | 4992.1.1.23 ↗ | extended segments › RelB-like › RelB-like › RelB-like › Seryl_tRNA_N | 0.82 | 72.0 | 5.98e-01 | 100.0% | 57.4% |
| 4026040 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.82 | 74.0 | 4.25e-01 | 100.0% | 38.6% |
| 3319132 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.81 | 72.0 | 5.60e-01 | 100.0% | 54.3% |
| 3770414 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.81 | 72.0 | 6.15e-01 | 100.0% | 66.7% |
| 3794577 | 3331.1.1.14 ↗ | a+b two layers › Uncharacterized protein yibL › Uncharacterized protein yibL › Uncharacterized protein yibL › CHDCT2 | 0.79 | 69.0 | 6.34e-01 | 100.0% | 74.1% |
| 5053017 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.79 | 72.0 | 5.47e-01 | 98.5% | 46.4% |
| 4260979 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.79 | 69.0 | 4.58e-01 | 100.0% | 24.9% |
| 3770066 | 3291.1.1.169 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › KIF21A_4th | 0.78 | 67.0 | 4.84e-01 | 100.0% | 39.0% |
| 3241140 | 2004.1.1.199 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23,SbcC_Walker_B | 0.78 | 67.0 | 3.85e-01 | 100.0% | 44.9% |
| 5057328 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.78 | 73.0 | 4.31e-01 | 100.0% | 28.2% |
| 3707409 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.77 | 68.0 | 5.64e-01 | 100.0% | 63.5% |
| 3829282 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.77 | 67.0 | 5.33e-01 | 100.0% | 48.1% |
| 3255143 | 630.1.1.0 ↗ | a+b complex topology › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain | 0.76 | 66.0 | 4.80e-01 | 100.0% | 37.3% |
| 3713350 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.75 | 68.0 | 5.46e-01 | 98.5% | 55.8% |
| 3733682 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.75 | 68.0 | 4.39e-01 | 98.5% | 24.7% |
| 3933048 | 4992.1.1.12 ↗ | extended segments › RelB-like › RelB-like › RelB-like › LIN9_C | 0.74 | 64.0 | 5.65e-01 | 100.0% | 65.0% |
| 3608075 | 603.1.1.218 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Flagellar_rod | 0.74 | 63.0 | 4.76e-01 | 100.0% | 38.2% |
| 3613538 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.72 | 62.0 | 4.74e-01 | 100.0% | 46.9% |
| 2485668 | 7025.1.1.2 ↗ | alpha bundles › LIN9-LIN52 heterodimer › LIN9-LIN52 heterodimer › LIN9-LIN52 heterodimer › LIN9_C | 0.70 | 60.0 | 5.60e-01 | 100.0% | 77.4% |
D4
medium
residues 837-955
Domain cluster:
representative