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ORF22

Euk-Vir

Human_gammaherpesvirus_8

ORF22__YP_001129375__Human_gammaherpesvirus_8__37296

Identity

Accession:
YP_001129375 ↗
Protein ID:
ORF22
Kingdom:
euk

Quality

82.9 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Rhadinovirus› Human_gammaherpesvirus_8

TaxID: 37296

Cluster

View cluster (43 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1-15_34-90
PDB
D2 high residues 549-695
PDB
Domain cluster: rep: UL22__YP_003084400__Anatid_alphaherpesvirus_1__104388__D647-783
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF17488.8 best Herpes_glycoH_C 192.6 3.50e-57 96.6% 98.6%
D3 medium residues 91-110_258-325
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 69.0 4.50e-19 76.1% 12.8%
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5w0kA01 3.90.380.20 Alpha Beta › Alpha-Beta Complex › Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 › Herpesvirus glycoprotein H, domain D-II 0.79 72.0 4.81e-01 100.0% 72.0%
1fpoC02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.75 55.0 5.52e-01 77.3% 92.3%
1quuA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 51.0 4.47e-01 70.5% 72.2%
3ck6C02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.71 50.0 4.46e-01 72.7% 79.0%
4nb5B02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.70 43.0 4.90e-01 79.5% 84.4%
1qdbA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.70 46.0 3.81e-01 78.4% 41.3%
4yjwA00 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.68 42.0 3.46e-01 80.7% 35.3%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.65 47.0 4.27e-01 76.1% 75.4%
4dylA02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.62 39.0 3.83e-01 79.5% 58.5%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.62 41.0 4.53e-01 80.7% 84.5%
2c2jA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.61 49.0 3.94e-01 85.2% 74.5%
1x0tA01 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.61 35.0 4.11e-01 73.9% 82.0%
6wv5A01 1.20.1440.130 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › VKOR domain 0.60 48.0 4.14e-01 85.2% 93.4%
1skvA00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.60 42.0 4.85e-01 78.4% 100.0%
2yw6B00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.60 48.0 3.99e-01 85.2% 80.0%
1b06A01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.59 39.0 4.41e-01 80.7% 89.6%
5ekdA02 1.10.240.10 Mainly Alpha › Orthogonal Bundle › Tyrosyl-Transfer RNA Synthetase › Tyrosyl-Transfer RNA Synthetase 0.59 40.0 3.75e-01 70.5% 84.7%
2v0xA01 1.10.287.3160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.58 44.0 3.54e-01 80.7% 63.7%
6xpdA01 1.20.1510.10 Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain 0.57 44.0 3.34e-01 80.7% 99.0%
3bt5A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.57 44.0 3.71e-01 83.0% 80.8%
3hhcC00 1.20.1250.60 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interferon lambda 0.57 46.0 3.75e-01 84.1% 62.3%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.56 43.0 4.16e-01 80.7% 76.8%
5ux1D00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.56 44.0 3.39e-01 84.1% 61.4%
1yg2A02 6.10.140.190 Special › Helix non-globular › Helix Hairpins › 0.55 46.0 4.63e-01 89.8% 91.1%
1e7pC00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.50 36.0 2.72e-01 77.3% 80.3%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3732399 622.1.1.0 ↗ alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain 0.75 54.0 5.39e-01 75.0% 85.6%
3185833 633.23.1.22 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.72 49.0 4.08e-01 70.5% 68.7%
4012877 106.1.1.0 ↗ alpha arrays › Globin-like › Globin-like › Globin-like 0.71 52.0 4.29e-01 77.3% 96.2%
3522864 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.69 48.0 4.50e-01 72.7% 83.6%
141918 101.1.2.49 ↗ alpha arrays › HTH › HTH › winged helix domain › PadR,Vir_act_alpha_C 0.67 47.0 3.82e-01 73.9% 49.4%
3802402 633.22.1.0 ↗ alpha bundles › Bromodomain-like › Vitamin K epoxide reductase (VKOR) › Vitamin K epoxide reductase (VKOR) 0.66 50.0 4.22e-01 83.0% 83.9%
3280466 101.1.2.48 ↗ alpha arrays › HTH › HTH › winged helix domain › PadR 0.65 47.0 3.74e-01 77.3% 46.8%
2507077 101.1.2.48 ↗ alpha arrays › HTH › HTH › winged helix domain › PadR 0.65 47.0 3.73e-01 75.0% 46.0%
3595968 605.2.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 0.62 44.0 4.61e-01 80.7% 80.0%
4650429 5055.1.1.0 ↗ extended segments › Small-conductance potassium channel › Small-conductance potassium channel › Small-conductance potassium channel 0.62 42.0 4.13e-01 78.4% 65.3%
3408441 633.10.1.30 ↗ alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › DUF7027 0.58 45.0 4.09e-01 84.1% 98.3%
2775346 3636.1.1.1 ↗ a+b two layers › XPD arch domain › XPD arch domain › XPD arch domain › HBB 0.56 47.0 3.68e-01 93.2% 78.3%
4961031 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.55 37.0 4.09e-01 79.5% 87.1%
3926892 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.53 46.0 3.20e-01 96.6% 63.0%
3399669 5050.1.1.1 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.51 43.0 2.83e-01 100.0% 60.8%
D4 medium residues 111-146_326-360
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 22.7 5.10e-05 54.9% 7.4%
PF02489.22 Herpes_glycop_H 25.2 8.60e-06 50.7% 7.0%
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5jciA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.57 39.0 2.79e-01 71.8% 78.2%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
None — 0.56 33.0 3.65e-01 76.1% 74.5%
4018180 4121.1.1.0 ↗ a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.53 40.0 2.70e-01 80.3% 46.3%
3807555 2003.1.2.24 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Pyr_redox_2 0.52 39.0 2.80e-01 78.9% 75.7%
D5 medium residues 147-257
PDB
Domain cluster: rep: orf22__YP_009044405__Alcelaphine_gammaherpesvirus_2__138184__D149-254
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 116.2 2.30e-33 99.1% 21.0%
CATH (22)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5w0kA01 3.90.380.20 Alpha Beta › Alpha-Beta Complex › Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 › Herpesvirus glycoprotein H, domain D-II 0.87 82.0 5.69e-01 100.0% 34.8%
1y8cA02 2.20.25.110 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › S-adenosyl-L-methionine-dependent methyltransferases 0.70 34.0 4.54e-01 83.8% 86.7%
3rbyA02 2.40.128.310 Mainly Beta › Beta Barrel › Lipocalin › Protein HRI1, C-terminal domain 0.68 39.0 4.24e-01 99.1% 66.3%
1x7dB01 3.30.1780.10 Alpha Beta › 2-Layer Sandwich › ornithine cyclodeaminase, domain 1 › ornithine cyclodeaminase, domain 1 0.68 47.0 4.03e-01 71.2% 79.9%
2it9A00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.65 38.0 3.71e-01 89.2% 53.3%
2nvnA00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.65 36.0 3.58e-01 89.2% 51.7%
4r80A00 3.10.450.630 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.64 38.0 4.56e-01 78.4% 86.8%
1a2vA03 2.70.98.20 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Copper amine oxidase, catalytic domain 0.63 53.0 3.54e-01 91.0% 84.5%
3w7tA01 2.70.98.50 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › putative glycoside hydrolase family protein from bacillus halodurans 0.60 50.0 3.94e-01 91.0% 78.4%
1d6uA03 2.70.98.20 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Copper amine oxidase, catalytic domain 0.59 49.0 3.30e-01 89.2% 91.2%
2vckA00 3.40.1500.20 Alpha Beta › 3-Layer(aba) Sandwich › oxygen-dependent coproporphyrinogen oxidase › 0.59 47.0 3.84e-01 85.6% 86.1%
2qziA00 3.40.1720.10 Alpha Beta › 3-Layer(aba) Sandwich › Streptococcus thermophilus LMG 18311 protein like › Streptococcus thermophilus LMG 18311 protein like 0.57 41.0 4.25e-01 74.8% 96.0%
4bboA00 2.40.128.30 Mainly Beta › Beta Barrel › Lipocalin › Avidin-like 0.56 45.0 4.54e-01 85.6% 90.3%
5gv0A00 2.40.160.110 Mainly Beta › Beta Barrel › Porin › 0.55 47.0 4.14e-01 91.0% 65.4%
4akmB00 2.40.160.110 Mainly Beta › Beta Barrel › Porin › 0.55 47.0 4.13e-01 91.0% 65.6%
6r3wA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.54 44.0 3.89e-01 86.5% 75.8%
1ydwA02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.54 42.0 3.42e-01 83.8% 77.2%
4fuvA00 2.40.160.170 Mainly Beta › Beta Barrel › Porin › 0.53 43.0 3.52e-01 88.3% 96.2%
1h91A00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.53 38.0 3.28e-01 75.7% 88.9%
6phxA03 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.52 36.0 3.79e-01 91.9% 83.2%
3klxB00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.51 42.0 3.57e-01 87.4% 61.3%
3pgbA01 2.70.98.20 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Copper amine oxidase, catalytic domain 0.51 45.0 2.96e-01 100.0% 70.9%
ECOD (30)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2701125 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.98 92.0 5.67e-01 100.0% 21.3%
2095478 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.85 80.0 5.00e-01 100.0% 22.2%
3812869 284.1.3.0 ↗ a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain 0.79 42.0 4.49e-01 93.7% 59.0%
3990496 12.1.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.74 39.0 4.87e-01 93.7% 82.9%
4569249 9.14.1.1 ↗ beta barrels › Lipocalins/Streptavidin › Uncharacterized protein YLR301W › Uncharacterized protein YLR301W › HRI1 0.69 38.0 4.15e-01 94.6% 65.6%
5009702 331.3.1.0 ↗ a+b two layers › TBP-like › Bet v1-like › Bet v1-like 0.67 47.0 4.30e-01 71.2% 73.6%
3408795 12.1.1.60 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › Chitin_bind_4 0.66 36.0 4.74e-01 93.7% 98.4%
4020496 12.3.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich 0.65 54.0 4.15e-01 91.0% 84.7%
3943894 77.1.1.7 ↗ beta meanders › open-sided beta-meander › Outer surface protein › Outer surface protein › DUF1481 0.64 41.0 3.95e-01 91.9% 57.6%
4008120 5.1.5.139 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › DUF1481 0.63 41.0 4.00e-01 91.9% 60.0%
3640072 12.3.1.2 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Cu_amine_oxid 0.63 52.0 3.46e-01 90.1% 80.2%
3576881 3347.1.1.0 ↗ beta meanders › Uncharacterized protein BF3112 › Uncharacterized protein BF3112 › Uncharacterized protein BF3112 0.63 43.0 4.56e-01 93.7% 79.0%
3864098 12.3.1.2 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Cu_amine_oxid 0.62 51.0 3.46e-01 90.1% 81.4%
3981044 867.1.1.1 ↗ a+b three layers › Coproporphyrinogen III oxidase › Coproporphyrinogen III oxidase › Coproporphyrinogen III oxidase › Coprogen_oxidas 0.59 47.0 3.58e-01 85.6% 79.6%
4277468 298.1.1.22 ↗ a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Gal80p_C-like 0.59 47.0 3.74e-01 83.8% 98.6%
3701925 292.2.1.0 ↗ a+b two layers › RIP/Polo-box domain › Polo-box domain › Polo-box domain 0.58 36.0 3.57e-01 91.9% 58.3%
4942439 4252.1.1.0 ↗ beta barrels › AttH-like › AttH-like › AttH-like 0.57 46.0 4.23e-01 86.5% 88.3%
3894207 3369.1.1.1 ↗ beta meanders › lysosome-associated membrane protein LAMP-3 › lysosome-associated membrane protein LAMP-3 › lysosome-associated membrane protein LAMP-3 › Lamp2-like_luminal 0.57 48.0 4.29e-01 90.1% 66.2%
437290 9.2.1.1 ↗ beta barrels › Lipocalins/Streptavidin › Avidin/Streptavidin › Avidin/Streptavidin › Avidin 0.56 46.0 4.25e-01 86.5% 92.0%
2034 12.3.1.2 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Cu_amine_oxid 0.56 46.0 3.07e-01 90.1% 82.4%
3686676 298.1.1.0 ↗ a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 0.56 39.0 3.34e-01 71.2% 48.6%
3264296 11.10.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › TRAF domain-like › TRAF domain-like 0.55 40.0 3.73e-01 76.6% 62.9%
185647 3369.1.1.1 ↗ beta meanders › lysosome-associated membrane protein LAMP-3 › lysosome-associated membrane protein LAMP-3 › lysosome-associated membrane protein LAMP-3 › Lamp2-like_luminal 0.54 46.0 4.13e-01 91.0% 66.5%
4031638 7089.1.1.1 ↗ a+b two layers › Methane monooxygenase hydroxylase, MmoD › Methane monooxygenase hydroxylase, MmoD › Methane monooxygenase hydroxylase, MmoD › DUF1108 0.53 32.0 3.62e-01 95.5% 77.6%
3229460 10.1.1.91 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › PF29324 0.52 39.0 3.11e-01 94.6% 39.5%
3326913 12.3.1.2 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Cu_amine_oxid 0.52 46.0 3.54e-01 96.4% 88.8%
4292366 9.1.1.14 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › CpeS 0.52 45.0 3.77e-01 92.8% 67.9%
3977969 9.11.1.0 ↗ beta barrels › Lipocalins/Streptavidin › YdhA-like › YdhA-like 0.51 37.0 3.80e-01 85.6% 77.3%
169754 12.3.1.2 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Cu_amine_oxid 0.51 45.0 3.03e-01 96.4% 70.8%
3840054 5084.1.1.15 ↗ beta barrels › Outer membrane meander beta-barrels › OMPA-like › OMPA-like › HP_OMP 0.50 40.0 3.77e-01 87.4% 92.9%
D6 medium residues 361-434
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 65.7 4.60e-18 100.0% 14.6%
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5j1hA01 1.20.58.1060 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 50.0 3.80e-01 78.4% 46.7%
3r6nA02 1.20.58.1060 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 49.0 3.92e-01 78.4% 54.8%
3di2A00 1.20.1250.50 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.63 44.0 3.85e-01 73.0% 73.0%
3nzpB03 1.20.58.930 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 42.0 4.13e-01 73.0% 83.5%
6q9jB02 1.20.1440.230 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain 0.60 44.0 4.17e-01 78.4% 78.4%
2l3lA01 1.20.58.1250 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain 0.59 45.0 4.08e-01 85.1% 77.4%
1vkeB00 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.58 41.0 3.76e-01 74.3% 64.4%
2ib0A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 45.0 3.86e-01 89.2% 100.0%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.57 43.0 4.07e-01 83.8% 95.7%
2zgyA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.57 40.0 3.21e-01 73.0% 60.0%
3lszA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 47.0 4.06e-01 100.0% 66.4%
2kz5A00 1.10.880.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor Skn-1; Chain P › Transcription factor, Skn-1-like, DNA-binding domain 0.54 37.0 3.53e-01 74.3% 58.2%
1sknP00 1.10.880.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor Skn-1; Chain P › Transcription factor, Skn-1-like, DNA-binding domain 0.54 37.0 3.70e-01 74.3% 71.6%
1bo9A00 1.10.220.10 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Annexin 0.51 38.0 3.88e-01 86.5% 84.9%
2kxpA01 3.30.1140.60 Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › F-actin capping protein, alpha subunit 0.51 37.0 3.40e-01 81.1% 86.0%
ECOD (25)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2701125 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.98 94.0 5.49e-01 100.0% 14.9%
3685439 109.54.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 0.70 57.0 3.26e-01 91.9% 9.4%
3738701 109.4.1.933 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_Trm732 0.69 56.0 3.71e-01 90.5% 42.2%
2080134 3232.1.2.0 ↗ alpha arrays › PB2 '627' domain-related › PB2 '627' domain-related 0.69 51.0 4.06e-01 79.7% 46.7%
5021005 2003.1.5.27 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › NAS 0.68 56.0 3.82e-01 94.6% 33.1%
5004483 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.68 52.0 4.99e-01 83.8% 90.6%
3548573 109.4.1.2161 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Telomere_reg-2, TELO2_ARM 0.66 52.0 3.20e-01 86.5% 27.2%
3910597 603.1.1.8 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Spectrin_2 0.65 52.0 4.37e-01 86.5% 72.0%
3397297 101.1.2.507 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_TANC1 0.65 48.0 3.83e-01 78.4% 41.4%
3883666 603.1.1.8 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Spectrin_2 0.64 47.0 4.60e-01 78.4% 100.0%
4147954 604.34.1.1 ↗ alpha bundles › Spectrin repeat-like › Helical bundle domain in arginine decarboxylase › Helical bundle domain in arginine decarboxylase › Arg_decarb_HB 0.63 48.0 4.50e-01 81.1% 80.0%
3232756 604.6.1.0 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.62 46.0 4.44e-01 79.7% 88.2%
3274332 604.5.1.0 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.59 45.0 3.01e-01 83.8% 86.6%
4048456 604.34.1.1 ↗ alpha bundles › Spectrin repeat-like › Helical bundle domain in arginine decarboxylase › Helical bundle domain in arginine decarboxylase › Arg_decarb_HB 0.58 44.0 4.23e-01 86.5% 81.1%
3390932 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.58 44.0 4.21e-01 83.8% 94.4%
3591259 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.58 44.0 3.45e-01 83.8% 52.9%
4181400 184.1.1.1 ↗ alpha arrays › Nucleoside phosphorylase/phosphoribosyltransferase-N › Nucleoside phosphorylase/phosphoribosyltransferase-N › Nucleoside phosphorylase/phosphoribosyltransferase-N › Glycos_trans_3N 0.58 41.0 4.33e-01 75.7% 90.8%
3387796 604.34.1.1 ↗ alpha bundles › Spectrin repeat-like › Helical bundle domain in arginine decarboxylase › Helical bundle domain in arginine decarboxylase › Arg_decarb_HB 0.56 43.0 4.09e-01 86.5% 80.0%
4012875 109.8.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Arp2/3 complex 16 KDa subunit ARPC5 › Arp2/3 complex 16 KDa subunit ARPC5 0.56 43.0 3.97e-01 89.2% 64.0%
3601415 101.7.1.0 ↗ alpha arrays › HTH › DEK-C › DEK-C 0.55 40.0 4.02e-01 77.0% 96.0%
4599610 102.1.1.5 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › SAM_LFY 0.54 39.0 3.56e-01 74.3% 86.3%
4615627 4973.1.1.1 ↗ alpha bundles › helical domain in DNA primase DnaG catalytic core › helical domain in DNA primase DnaG catalytic core › helical domain in DNA primase DnaG catalytic core › DnaB_bind 0.54 37.0 3.70e-01 71.6% 89.3%
3203935 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 41.0 3.12e-01 89.2% 86.0%
3686422 621.1.1.0 ↗ alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain 0.53 37.0 3.35e-01 74.3% 93.3%
4169130 102.1.1.5 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › SAM_LFY 0.51 35.0 3.36e-01 71.6% 58.9%
D7 medium residues 435-545
PDB
Domain cluster: rep: envelope_glycoprotein_H__YP_009388523__Common_bottlenose_dolphin_gammaherpesvirus_1_strain_Sarasota__2022783__D447-588
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 141.8 4.00e-41 100.0% 22.0%