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ORF22

Euk-Vir

Macaca_nemestrina_rhadinovirus_2

ORF22__YP_010084564__Macaca_nemestrina_rhadinovirus_2__123630

Identity

Accession:: YP_010084564 ↗
Protein ID:: ORF22
Kingdom:: euk

Quality

80.4 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Rhadinovirus› Macaca_nemestrina_rhadinovirus_2

TaxID: 123630

Cluster

View cluster (43 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 550-692

PDB

Domain cluster: rep: UL22__YP_003084400__Anatid_alphaherpesvirus_1__104388__D647-783

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF17488.8 best	Herpes_glycoH_C	158.9	9.30e-47	100.0%	99.3%

CATH (8)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
7b7nH01	2.60.40.3190	Mainly Beta › Sandwich › Immunoglobulin-like › Herpesvirus glycoprotein H, C-terminal domain	0.92	80.0	8.51e-01	90.9%	100.0%
2xqyA03	2.60.40.3190	Mainly Beta › Sandwich › Immunoglobulin-like › Herpesvirus glycoprotein H, C-terminal domain	0.88	77.0	8.04e-01	99.3%	98.5%
3m1cA04	2.60.40.3190	Mainly Beta › Sandwich › Immunoglobulin-like › Herpesvirus glycoprotein H, C-terminal domain	0.87	75.0	7.78e-01	92.3%	96.2%
1u7iA02	3.30.720.110	Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 ›	0.62	27.0	4.03e-01	77.6%	96.7%
1f9qD00	2.40.50.40	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) ›	0.61	24.0	3.50e-01	71.3%	78.8%
7b9cA02	2.130.10.10	Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase	0.54	42.0	3.14e-01	83.2%	60.9%
2xtlA02	2.60.40.1140	Mainly Beta › Sandwich › Immunoglobulin-like › Collagen-binding surface protein Cna, B-type domain	0.50	31.0	3.62e-01	72.7%	86.9%
5e9aB03	2.60.40.1180	Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II	0.50	22.0	3.15e-01	86.7%	90.3%

ECOD (7)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1936537	3145.1.1.1 ↗	beta sandwiches › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › Herpes_glycoH_C	0.88	84.0	8.34e-01	100.0%	95.3%
1309233	3145.1.1.1 ↗	beta sandwiches › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › Herpes_glycoH_C	0.85	77.0	7.68e-01	99.3%	91.9%
4830885	3145.1.1.1 ↗	beta sandwiches › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › Herpes_glycoH_C	0.84	59.0	6.97e-01	72.7%	99.0%
2095502	3145.1.1.1 ↗	beta sandwiches › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › Herpes_glycoH_C	0.84	79.0	7.88e-01	100.0%	96.6%
119479	3145.1.1.1 ↗	beta sandwiches › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › Herpes_glycoH_C	0.81	77.0	7.67e-01	100.0%	96.6%
3981129	7089.1.1.5 ↗	a+b two layers › Methane monooxygenase hydroxylase, MmoD › Methane monooxygenase hydroxylase, MmoD › Methane monooxygenase hydroxylase, MmoD › PF30110	0.58	31.0	3.98e-01	90.9%	88.2%
1069248	3612.1.1.1 ↗	a+b two layers › Pesticin N-terminal domain › Pesticin N-terminal domain › Pesticin N-terminal domain › Pesticin_RB	0.55	42.0	4.06e-01	92.3%	69.9%

D2 medium residues 87-111_137-279

PDB

Domain cluster: rep: gH__YP_010087392__Vombatid_gammaherpesvirus_1__2052651__D82-121_163-275

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02489.22 best	Herpes_glycop_H	51.1	1.20e-13	96.4%	29.3%

CATH (4)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5w0kA01	3.90.380.20	Alpha Beta › Alpha-Beta Complex › Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 › Herpesvirus glycoprotein H, domain D-II	0.83	79.0	6.21e-01	100.0%	61.2%
1nkgA01	2.70.98.10	Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 ›	0.60	42.0	3.67e-01	71.4%	89.6%
3rbyA02	2.40.128.310	Mainly Beta › Beta Barrel › Lipocalin › Protein HRI1, C-terminal domain	0.59	28.0	3.57e-01	77.4%	75.8%
6jptA00	3.30.230.90	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 ›	0.54	31.0	3.53e-01	73.8%	74.4%

ECOD (11)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2701125	3146.1.1.1 ↗	a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H	0.84	81.0	5.56e-01	100.0%	37.4%
2095478	3146.1.1.1 ↗	a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H	0.82	77.0	5.34e-01	100.0%	39.1%
2095503	3146.1.1.1 ↗	a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H	0.74	70.0	4.81e-01	100.0%	39.1%
4569249	9.14.1.1 ↗	beta barrels › Lipocalins/Streptavidin › Uncharacterized protein YLR301W › Uncharacterized protein YLR301W › HRI1	0.61	27.0	3.58e-01	72.0%	74.4%
4020496	12.3.1.0 ↗	beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich	0.60	43.0	3.70e-01	71.4%	91.0%
3474062	331.3.1.4 ↗	a+b two layers › TBP-like › Bet v1-like › Bet v1-like › IP_trans	0.59	51.0	4.34e-01	93.5%	86.4%
3167013	9.14.1.1 ↗	beta barrels › Lipocalins/Streptavidin › Uncharacterized protein YLR301W › Uncharacterized protein YLR301W › HRI1	0.59	28.0	3.58e-01	79.8%	77.7%
3910253	216.1.1.4 ↗	a+b two layers › UBC-like › UBC-like › UBC-like › RWD	0.54	30.0	3.67e-01	79.8%	83.8%
3752441	216.1.1.4 ↗	a+b two layers › UBC-like › UBC-like › UBC-like › RWD	0.54	30.0	3.52e-01	80.4%	74.2%
3977969	9.11.1.0 ↗	beta barrels › Lipocalins/Streptavidin › YdhA-like › YdhA-like	0.54	28.0	3.39e-01	82.1%	74.5%
3998265	331.3.1.4 ↗	a+b two layers › TBP-like › Bet v1-like › Bet v1-like › IP_trans	0.53	47.0	4.09e-01	95.8%	84.8%

D3 medium residues 480-549

PDB

Domain cluster: rep: envelope_glycoprotein_H__NP_042618__Equid_gammaherpesvirus_2__12657__D496-575

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02489.22 best	Herpes_glycop_H	48.1	1.00e-12	91.4%	12.0%