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ORF23_gene_product

Euk-Vir

Equid_alphaherpesvirus_8

ORF23_gene_product__YP_006273002__Equid_alphaherpesvirus_8__39637

Identity

Accession:: YP_006273002 ↗
Protein ID:: ORF23_gene_product
Kingdom:: euk

Quality

74.4 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Varicellovirus› Equid_alphaherpesvirus_8

TaxID: 39637

Cluster

View cluster (39 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 587-711

PDB

Domain cluster: rep: tegument_protein_UL37__YP_002333504__Equid_alphaherpesvirus_9__55744__D621-714

D2 medium residues 48-100

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03970.19 best	Herpes_UL37_1	30.8	2.50e-07	100.0%	18.7%

CATH (18)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4e4eA01	1.10.287.990	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain	0.71	50.0	4.60e-01	75.5%	57.7%
1lrzA03	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.69	51.0	4.87e-01	77.4%	67.7%
1hr5A00	1.20.5.420	Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C	0.68	53.0	5.48e-01	84.9%	93.8%
2nr4A02	1.20.58.290	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121.	0.67	48.0	4.67e-01	77.4%	69.0%
1a36A04	1.10.132.10	Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 ›	0.66	50.0	3.45e-01	75.5%	22.9%
4atgA00	1.25.40.770	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TAF6, C-terminal HEAT repeat domain	0.65	53.0	3.58e-01	88.7%	26.7%
8gj8A01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.65	54.0	3.57e-01	100.0%	24.8%
4g1tA03	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.63	46.0	3.08e-01	83.0%	18.6%
2ic6A00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.59	46.0	4.33e-01	94.3%	94.4%
2e9xA01	1.20.58.1030	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.58	46.0	3.71e-01	100.0%	66.4%
3da1A03	1.10.8.870	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Alpha-glycerophosphate oxidase, cap domain	0.58	44.0	3.42e-01	90.6%	35.3%
3q1pA01	6.10.250.1120	Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces ›	0.57	37.0	3.97e-01	73.6%	92.3%
8fbnB01	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.57	45.0	3.16e-01	100.0%	45.9%
4eqqA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.57	37.0	3.80e-01	84.9%	72.9%
7b9cA02	2.130.10.10	Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase	0.56	45.0	2.74e-01	92.5%	30.1%
4zmuA02	3.30.70.270	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain	0.55	46.0	3.33e-01	94.3%	48.4%
5v07Z01	3.40.50.1010	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease	0.53	42.0	2.96e-01	96.2%	84.5%
1h4xA00	3.30.750.24	Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › STAS domain	0.53	41.0	3.28e-01	86.8%	61.3%

ECOD (18)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3604094	180.1.1.1 ↗	alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › PAP2	0.73	61.0	4.32e-01	94.3%	84.2%
4201121	192.7.1.0 ↗	alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm	0.72	52.0	5.03e-01	75.5%	68.3%
1108845	150.1.1.0 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin	0.72	53.0	5.52e-01	81.1%	87.5%
4462677	2004.1.1.363 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD-helicase+UvrD_C	0.71	62.0	3.37e-01	100.0%	32.9%
4488200	604.12.1.0 ↗	alpha bundles › Spectrin repeat-like › MIT domain › MIT domain	0.70	52.0	4.20e-01	83.0%	73.4%
5054469	192.7.1.2 ↗	alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N	0.69	50.0	4.06e-01	77.4%	39.0%
5032313	101.1.2.150 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_45	0.69	51.0	4.02e-01	79.2%	73.6%
5039785	632.22.1.200 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › PF26119	0.67	54.0	4.51e-01	90.6%	66.0%
1203190	192.3.1.1 ↗	alpha bundles › Long alpha-hairpin › Fe,Mn superoxide dismutase (SOD), N-terminal domain › Fe,Mn superoxide dismutase (SOD), N-terminal domain › Sod_Fe_N	0.67	49.0	4.16e-01	81.1%	45.2%
3258925	192.8.1.0 ↗	alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain	0.66	48.0	4.44e-01	75.5%	78.6%
4784166	192.29.1.0 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding)	0.63	49.0	4.53e-01	84.9%	64.3%
5048408	605.1.1.1 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA	0.63	49.0	4.86e-01	86.8%	89.1%
3271624	2004.1.1.184 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11	0.63	51.0	3.03e-01	92.5%	12.9%
5001984	605.1.1.1 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA	0.61	48.0	4.95e-01	88.7%	98.0%
315449	192.8.1.2 ↗	alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › Hanta_nucleocap	0.60	45.0	4.21e-01	92.5%	96.1%
5009848	2006.1.4.2 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PIN	0.57	44.0	3.80e-01	96.2%	79.0%
3990469	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.57	46.0	2.75e-01	100.0%	11.4%
2883289	212.1.1.6 ↗	a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal_S9	0.52	40.0	2.63e-01	98.1%	24.6%

D3 medium residues 101-225

PDB

Domain cluster: rep: tegument_protein_UL37__YP_009176900__Testudinid_alphaherpesvirus_3__2560801__D149-260

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03970.19 best	Herpes_UL37_1	101.3	7.90e-29	100.0%	42.3%

D4 medium residues 226-314

PDB

Domain cluster: rep: tegument_protein_UL37__YP_009176900__Testudinid_alphaherpesvirus_3__2560801__D261-389

D5 medium residues 315-406_418-490

PDB

Domain cluster: rep: tegument_protein_UL37__YP_068340__Suid_alphaherpesvirus_1__10345__D296-434

D6 medium residues 491-548

PDB

Domain cluster: rep: tegument_protein_UL37__NP_073331__Meleagrid_alphaherpesvirus_1__37108__D492-544

D7 medium residues 712-870

PDB

Domain cluster: rep: tegument_protein_UL37__YP_164480__Cercopithecine_alphaherpesvirus_2__10317__D861-972