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ORF24

Euk-Vir

Human_gammaherpesvirus_8

ORF24__YP_001129377__Human_gammaherpesvirus_8__37296

Identity

Accession:
YP_001129377 ↗
Protein ID:
ORF24
Kingdom:
euk

Quality

65.9 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Rhadinovirus› Human_gammaherpesvirus_8

TaxID: 37296

Cluster

View cluster (22 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 216-343_383-393
PDB
Domain cluster: rep: ORF16__NP_733869__Callitrichine_gammaherpesvirus_3__106331__D190-345
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03043.21 best Herpes_UL87 98.6 5.00e-28 97.8% 25.1%
D2 high residues 678-727
PDB
D3 medium residues 7-20_78-121
PDB
Domain cluster: representative
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7uzsX02 3.90.260.10 Alpha Beta › Alpha-Beta Complex › Coagulation Factor XIII; Chain A, domain 2 › Transglutaminase-like 0.55 40.0 2.63e-01 75.9% 37.2%
1a79A01 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.54 44.0 3.71e-01 91.4% 87.0%
2gw6A01 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.52 41.0 3.36e-01 89.7% 97.4%
3ieyB00 3.40.1350.150 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.51 41.0 3.08e-01 89.7% 77.0%
1r0vA01 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.50 40.0 3.71e-01 89.7% 87.0%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3385663 7547.1.1.1 ↗ a/b three-layered sandwiches › Hypothetical protein TT1679 › Hypothetical protein TT1679 › Hypothetical protein TT1679 › Antibiotic_NAT 0.56 43.0 2.91e-01 89.7% 88.2%
D4 medium residues 21-77_122-212
PDB
Domain cluster: rep: hypothetical_protein__YP_009551834__Rhinolophus_gammaherpesvirus_1__2054179__D30-81_138-219
D5 medium residues 597-656
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03043.21 best Herpes_UL87 94.5 8.80e-27 100.0% 11.4%
CATH (38)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1jwjA01 3.90.340.10 Alpha Beta › Alpha-Beta Complex › Nitric Oxide Synthase; Chain A, domain 1 › Nitric Oxide Synthase; Chain A, domain 1 0.70 51.0 3.76e-01 85.0% 28.4%
2aplA01 1.10.8.330 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › PG0816-like 0.69 54.0 5.25e-01 86.7% 88.2%
3ed5A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.69 53.0 4.72e-01 83.3% 84.5%
1q5nA03 1.10.40.30 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) 0.64 48.0 4.45e-01 90.0% 63.0%
3tw6A06 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.63 42.0 4.40e-01 100.0% 75.9%
3jr7A01 3.40.50.10440 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Dihydroxyacetone kinase; domain 1 0.62 50.0 4.01e-01 88.3% 95.8%
1td6A03 1.10.472.40 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Hypothetical protein mg237 homolog; domain 3 0.62 53.0 4.68e-01 100.0% 65.2%
2aj6A00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.62 46.0 3.71e-01 78.3% 60.8%
1uaaA02 1.10.10.160 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.61 46.0 4.31e-01 80.0% 81.1%
1nxhA00 1.10.3070.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein MTH393 › EhaM-like 0.61 51.0 4.12e-01 98.3% 46.8%
2go7A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.61 43.0 4.20e-01 88.3% 67.2%
5z5mA01 1.10.3330.10 Mainly Alpha › Orthogonal Bundle › UraD-like › Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase 0.60 42.0 3.23e-01 85.0% 30.2%
3lupA01 3.40.50.10170 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.60 48.0 3.66e-01 91.7% 97.4%
3vkhB07 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 45.0 3.21e-01 81.7% 31.2%
2fp1B00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.60 51.0 3.84e-01 100.0% 50.6%
2r0qC02 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.60 37.0 3.90e-01 75.0% 69.1%
3fdjA01 3.40.50.10440 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Dihydroxyacetone kinase; domain 1 0.59 47.0 3.88e-01 88.3% 98.2%
3nbiA01 1.10.8.1020 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › RecQ-mediated genome instability protein 1, N-terminal domain 0.58 45.0 4.64e-01 91.7% 91.4%
3pvzB00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.58 49.0 3.12e-01 93.3% 53.3%
1r6bX03 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.57 46.0 4.25e-01 100.0% 73.9%
1vt0k00 1.10.3230.20 Mainly Alpha › Orthogonal Bundle › Hypothetical protein yqbg › P22 tail accessory factor (Gp4) 0.56 47.0 3.63e-01 96.7% 61.4%
2b3tA01 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.56 43.0 3.96e-01 90.0% 79.8%
2zxqA06 1.20.1270.70 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle 0.55 45.0 4.45e-01 98.3% 95.5%
2o5rA04 1.10.8.70 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Glutamate-tRNA synthetase, class I, anticodon-binding domain 1 0.55 38.0 4.08e-01 88.3% 93.8%
2ygwA01 1.20.140.90 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Malonyl-CoA decarboxylase, oligemerization domain 0.55 38.0 2.84e-01 71.7% 55.6%
2p0tA02 1.10.60.30 Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › PSPTO4464-like domains 0.54 43.0 4.13e-01 96.7% 75.0%
1sr9A02 3.30.160.270 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Alpha-isopropylmalate synthase LeuA, regulatory domain 0.54 45.0 3.42e-01 100.0% 92.7%
1b1uA00 1.10.110.10 Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › Plant lipid-transfer and hydrophobic proteins 0.54 42.0 3.47e-01 86.7% 55.6%
2y44A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.53 43.0 3.17e-01 95.0% 87.0%
1v1gA00 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.53 43.0 3.24e-01 100.0% 96.8%
1f45B00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.53 42.0 3.27e-01 86.7% 97.0%
5deqB02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 38.0 3.50e-01 78.3% 71.1%
1h3fA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.53 39.0 2.82e-01 81.7% 27.7%
3bg5B07 1.10.10.2790 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.52 37.0 4.03e-01 100.0% 97.8%
1v07A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.52 39.0 3.32e-01 85.0% 76.4%
2w00A02 3.90.640.50 Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › 0.51 41.0 3.98e-01 100.0% 83.6%
4dccA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.51 39.0 3.72e-01 93.3% 73.0%
1jcfA03 3.90.640.10 Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 0.50 41.0 3.85e-01 95.0% 73.7%
ECOD (42)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5033498 103.1.1.0 ↗ alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.69 51.0 5.39e-01 88.3% 98.0%
3742957 103.4.1.0 ↗ alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein 0.66 49.0 4.97e-01 83.3% 90.0%
3604752 245.2.1.0 ↗ a+b two layers › Ribonuclease PH domain 2-like › YbaB › YbaB 0.66 50.0 3.89e-01 86.7% 85.5%
3646269 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.66 56.0 4.93e-01 100.0% 67.4%
4961037 103.1.1.0 ↗ alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.65 50.0 5.17e-01 98.3% 94.5%
4361639 103.1.1.6 ↗ alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › RuvA_C 0.64 50.0 4.64e-01 100.0% 65.8%
3203088 3924.1.1.1 ↗ alpha complex topology › Sterol uptake control protein 2 › Sterol uptake control protein 2 › Sterol uptake control protein 2 › Fungal_trans_2 0.63 49.0 3.14e-01 86.7% 31.2%
5019472 327.11.2.13 ↗ a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_PNO1_2nd 0.63 53.0 4.62e-01 100.0% 72.0%
5011341 4049.1.1.0 ↗ alpha superhelices › alpha-helical domain in siroheme synthase middle domains-like › alpha-helical domain in siroheme synthase middle domains-like › alpha-helical domain in siroheme synthase middle domains-like 0.63 49.0 4.96e-01 90.0% 90.0%
4989211 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.63 55.0 3.66e-01 100.0% 40.4%
5010724 101.1.11.0 ↗ alpha arrays › HTH › HTH › Ribbon-helix-helix 0.62 43.0 4.05e-01 71.7% 60.0%
3938558 4979.2.1.1 ↗ alpha arrays › C-terminal domain of Hypothetical protein MPN330-like › XRN2-binding domain (XTBD) › XRN2-binding domain (XTBD) › XTBD 0.62 46.0 4.05e-01 98.3% 53.3%
4948061 327.11.2.0 ↗ a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.61 52.0 4.48e-01 100.0% 72.0%
3116 643.1.1.1 ↗ alpha arrays › Hypothetical protein MTH393 › Hypothetical protein MTH393 › Hypothetical protein MTH393 › DUF1959 0.61 51.0 4.12e-01 98.3% 46.8%
3165239 2003.1.1.28 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › TrkA_N 0.61 43.0 3.03e-01 75.0% 22.6%
3988117 162.1.1.0 ↗ alpha bundles › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD 0.61 53.0 4.31e-01 100.0% 87.8%
3624622 108.1.1.0 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand 0.61 52.0 4.71e-01 100.0% 70.6%
4967653 103.11.1.3 ↗ alpha arrays › RuvA-C › RMI1 N-terminal helical domain-related › RMI1 N-terminal helical domain-related › PadR 0.61 48.0 4.89e-01 91.7% 100.0%
3602245 4953.1.1.0 ↗ beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like 0.61 45.0 4.46e-01 83.3% 81.5%
2833148 1128.1.1.1 ↗ alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR 0.60 51.0 4.24e-01 100.0% 66.1%
4155521 518.1.1.0 ↗ alpha arrays › Chemotaxis receptor methyltransferase CheR, N-terminal domain › Chemotaxis receptor methyltransferase CheR, N-terminal domain › Chemotaxis receptor methyltransferase CheR, N-terminal domain 0.60 49.0 4.72e-01 91.7% 90.0%
3987616 377.1.1.11 ↗ few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › RecO_C 0.60 48.0 3.68e-01 98.3% 35.2%
4597950 377.1.1.0 ↗ few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like 0.60 48.0 3.68e-01 98.3% 35.2%
3591437 601.29.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › TM1646-like › TM1646-like 0.60 49.0 4.20e-01 93.3% 60.0%
4073199 101.1.11.190 ↗ alpha arrays › HTH › HTH › Ribbon-helix-helix › DUF2610 0.60 42.0 4.70e-01 80.0% 97.8%
5075956 2006.1.1.18 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › HAD_2 0.59 47.0 3.23e-01 91.7% 25.5%
2858351 1128.1.1.2 ↗ alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR_2 0.59 46.0 3.88e-01 91.7% 65.5%
4030952 377.1.1.11 ↗ few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › RecO_C 0.59 47.0 3.57e-01 98.3% 34.1%
3519127 4979.2.1.1 ↗ alpha arrays › C-terminal domain of Hypothetical protein MPN330-like › XRN2-binding domain (XTBD) › XRN2-binding domain (XTBD) › XTBD 0.58 43.0 3.97e-01 93.3% 58.7%
3486635 4979.2.1.1 ↗ alpha arrays › C-terminal domain of Hypothetical protein MPN330-like › XRN2-binding domain (XTBD) › XRN2-binding domain (XTBD) › XTBD 0.58 41.0 4.03e-01 93.3% 67.7%
4981747 632.15.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) 0.57 44.0 4.35e-01 88.3% 83.1%
1514559 11.1.1.49 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › LPMO_10 0.56 44.0 2.93e-01 88.3% 26.2%
3925179 1128.1.1.0 ↗ alpha bundles › LYR protein › LYR protein › LYR protein 0.55 41.0 3.85e-01 88.3% 63.7%
3550682 3599.1.1.1 ↗ alpha superhelices › Mitochondrial malonyl-CoA decarboxylase helical domain › Mitochondrial malonyl-CoA decarboxylase helical domain › Mitochondrial malonyl-CoA decarboxylase helical domain › MCD_N 0.55 41.0 3.02e-01 78.3% 54.2%
5009776 601.33.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain 0.55 46.0 3.83e-01 93.3% 65.7%
4525688 518.1.1.1 ↗ alpha arrays › Chemotaxis receptor methyltransferase CheR, N-terminal domain › Chemotaxis receptor methyltransferase CheR, N-terminal domain › Chemotaxis receptor methyltransferase CheR, N-terminal domain › CheR_N 0.53 46.0 4.14e-01 100.0% 81.2%
4406283 6056.1.1.2 ↗ alpha arrays › SP1917-like › SP1917-like › SP1917-like › PrmC_N 0.53 44.0 4.24e-01 98.3% 87.1%
4530474 102.1.1.0 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.52 37.0 3.48e-01 83.3% 58.7%
4030833 2006.1.1.18 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › HAD_2 0.52 42.0 2.99e-01 98.3% 30.2%
3195070 109.4.1.128 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MIF4G_like_2 0.51 42.0 2.70e-01 93.3% 83.1%
3502686 2484.1.1.88 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › ParM_N 0.51 36.0 2.72e-01 75.0% 72.1%
3183972 109.4.1.70 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID 0.50 41.0 2.89e-01 90.0% 27.0%