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ORF26

Euk-Vir

Macaca_nemestrina_rhadinovirus_2

ORF26__YP_010084568__Macaca_nemestrina_rhadinovirus_2__123630

Identity

Accession:
YP_010084568 ↗
Protein ID:
ORF26
Kingdom:
euk

Quality

84.7 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Rhadinovirus› Macaca_nemestrina_rhadinovirus_2

TaxID: 123630

Cluster

View cluster (76 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 6-140_285-303
PDB
Domain cluster: rep: capsid_triplex_subunit_2__NP_077456__Cercopithecine_alphaherpesvirus_9__35246__D3-114_290-314
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01802.24 best Herpes_V23 168.6 2.90e-49 90.3% 44.6%
D2 medium residues 142-214
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01802.24 best Herpes_V23 55.6 7.80e-15 100.0% 23.0%
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1zarA03 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.63 46.0 4.26e-01 79.5% 92.8%
5xd6B02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.62 48.0 3.63e-01 84.9% 85.1%
2gf2A02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.61 49.0 4.05e-01 89.0% 91.0%
4bwkB01 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.60 47.0 3.25e-01 86.3% 49.1%
5hvqC02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.60 50.0 4.64e-01 97.3% 87.8%
5kkrB02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.60 45.0 3.45e-01 82.2% 89.5%
1yjgA00 1.20.120.240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 0.60 46.0 3.68e-01 86.3% 93.6%
2bgcA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.59 49.0 4.49e-01 95.9% 91.1%
1vpdA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.58 49.0 4.08e-01 93.2% 90.1%
2zmdA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.58 45.0 3.53e-01 86.3% 91.1%
2fsjA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.54 36.0 2.93e-01 75.3% 36.2%
3hz6A02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.54 47.0 3.27e-01 98.6% 49.8%
1go4A00 3.30.900.10 Alpha Beta › 2-Layer Sandwich › Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A › HORMA domain 0.54 48.0 3.52e-01 100.0% 88.3%
1dliA03 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.54 46.0 4.31e-01 94.5% 97.8%
1ni5A01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.54 42.0 2.98e-01 84.9% 66.5%
1gzsB00 1.10.4120.10 Mainly Alpha › Orthogonal Bundle › SopE-like GEF fold › SopE-like, GEF domain 0.52 45.0 3.55e-01 100.0% 60.6%
1kagA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 42.0 3.32e-01 90.4% 89.9%
3qyfA03 1.10.10.1690 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Uncharacterised CRISPR-associated protein family, UPF0236 0.52 40.0 4.31e-01 83.6% 100.0%
1bjaA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 43.0 3.97e-01 94.5% 77.9%
1lnwF01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 42.0 3.60e-01 94.5% 71.8%
3pvlA03 1.20.80.10 Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › 0.50 42.0 3.69e-01 97.3% 66.9%
ECOD (31)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3859118 109.4.1.1452 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_Maestro, HEAT_Maestro_2 0.72 51.0 3.18e-01 75.3% 28.0%
3711299 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.70 49.0 4.07e-01 72.6% 53.6%
3516337 604.7.1.0 ↗ alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A 0.69 49.0 4.24e-01 74.0% 95.5%
3289865 1075.1.1.4 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_3 0.66 53.0 3.76e-01 89.0% 52.1%
3443484 616.1.1.0 ↗ alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain 0.65 49.0 4.95e-01 80.8% 94.6%
3211053 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.65 45.0 3.57e-01 74.0% 54.2%
4997039 1075.1.2.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.61 54.0 4.14e-01 98.6% 63.5%
4936803 876.1.1.4 ↗ a+b complex topology › ParB/Sulfiredoxin › ParB/Sulfiredoxin › ParB/Sulfiredoxin › DUF262 0.60 52.0 3.88e-01 100.0% 48.2%
3482896 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.57 47.0 3.03e-01 90.4% 41.7%
2760149 101.1.15.1 ↗ alpha arrays › HTH › HTH › HAT1, C-terminal domain › MOZ_SAS 0.57 48.0 4.44e-01 91.8% 82.6%
5032361 129.1.1.3 ↗ alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › UDPG_MGDP_dh 0.57 45.0 4.17e-01 83.6% 90.0%
4214015 101.11.1.0 ↗ alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 0.57 45.0 3.99e-01 89.0% 80.9%
4028665 101.1.2.303 ↗ alpha arrays › HTH › HTH › winged helix domain › RPC5 0.56 49.0 3.80e-01 100.0% 58.8%
3165053 5060.2.1.1 ↗ alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF 0.56 46.0 3.74e-01 90.4% 77.9%
2583940 601.7.1.8 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › Cas_Csm6_HEPN 0.54 44.0 3.50e-01 95.9% 91.4%
3245113 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 38.0 2.91e-01 76.7% 33.5%
3591799 101.1.11.0 ↗ alpha arrays › HTH › HTH › Ribbon-helix-helix 0.54 36.0 3.75e-01 89.0% 76.9%
5034071 129.1.1.3 ↗ alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › UDPG_MGDP_dh 0.54 45.0 3.93e-01 90.4% 79.1%
4947111 129.1.1.0 ↗ alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like 0.54 45.0 4.06e-01 90.4% 87.0%
3201764 101.1.15.1 ↗ alpha arrays › HTH › HTH › HAT1, C-terminal domain › MOZ_SAS 0.54 48.0 4.14e-01 100.0% 71.3%
4927679 129.1.1.3 ↗ alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › UDPG_MGDP_dh 0.54 46.0 4.07e-01 93.2% 82.9%
3955786 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.53 35.0 3.57e-01 75.3% 70.0%
3230011 6106.1.1.0 ↗ extended segments › Photosystem II protein Y, psbY › Photosystem II protein Y, psbY › Photosystem II protein Y, psbY 0.53 37.0 3.53e-01 72.6% 62.4%
5027489 129.1.1.3 ↗ alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › UDPG_MGDP_dh 0.53 44.0 3.90e-01 90.4% 81.9%
5051886 5054.1.1.0 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.53 39.0 3.77e-01 89.0% 70.0%
4945019 2003.1.1.370 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › UDPG_MGDP_dh 0.53 45.0 2.91e-01 91.8% 26.5%
4940163 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.52 46.0 4.13e-01 97.3% 82.0%
2613 101.1.2.105 ↗ alpha arrays › HTH › HTH › winged helix domain › MotA_activ 0.51 43.0 3.97e-01 94.5% 77.9%
3712944 3236.1.1.3 ↗ alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Mem_trans 0.51 43.0 2.85e-01 95.9% 60.3%
3486684 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.51 46.0 3.02e-01 100.0% 47.9%
3493622 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.51 46.0 3.00e-01 100.0% 47.2%
D3 medium residues 218-281
PDB
Domain cluster: rep: capsid_protein__YP_004207862__Cricetid_gammaherpesvirus_2__1605972__D219-292
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01802.24 best Herpes_V23 53.4 3.60e-14 100.0% 23.3%