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ORF29
Euk-VirHuman_gammaherpesvirus_8
ORF29__YP_001129382__Human_gammaherpesvirus_8__37296
Identity
- Accession:
- YP_001129382 ↗
- Protein ID:
- ORF29
- Kingdom:
- euk
Quality
76.9
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Rhadinovirus›
Human_gammaherpesvirus_8
TaxID: 37296
Cluster
View cluster (63 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 24-137
Domain cluster:
rep: ORF29A__YP_010084577__Macaca_nemestrina_rhadinovirus_2__123630__D25-83_114-155
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02500.23 best | DNA_pack_N | 45.1 | 1.40e-11 | 86.8% | 34.0% |
D2
high
residues 456-619_662-682
Domain cluster:
rep: tegument_protein_UL16__YP_010087586__Cervid_alphaherpesvirus_3__2115790__D494-638_653-663
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02499.23 best | DNA_pack_C | 220.0 | 7.20e-65 | 89.2% | 47.0% |
CATH (30)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3n4pC00 | 3.30.420.320 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › DNA-packaging terminase, C-terminal nuclease domain | 0.90 | 88.0 | 8.19e-01 | 100.0% | 93.1% |
| 2e2oA01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.68 | 45.0 | 5.20e-01 | 93.0% | 92.4% |
| 3c6aA00 | 3.30.420.240 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › | 0.68 | 62.0 | 6.11e-01 | 99.5% | 89.9% |
| 8oqkA01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.68 | 39.0 | 4.98e-01 | 89.7% | 100.0% |
| 2ivnA01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.66 | 51.0 | 5.33e-01 | 93.5% | 87.5% |
| 2qm1B01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.64 | 50.0 | 5.47e-01 | 95.1% | 98.7% |
| 5gujA02 | 3.40.1360.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 › | 0.64 | 40.0 | 4.85e-01 | 100.0% | 92.8% |
| 2f9wA01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.64 | 44.0 | 5.17e-01 | 92.4% | 99.2% |
| 3bexA01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.64 | 46.0 | 5.24e-01 | 90.8% | 100.0% |
| 4kreA04 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.61 | 50.0 | 4.47e-01 | 85.9% | 84.0% |
| 3c65A00 | 3.30.420.340 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › UvrC, RNAse H endonuclease domain | 0.61 | 44.0 | 4.83e-01 | 85.4% | 90.7% |
| 4h0oA02 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.61 | 46.0 | 4.46e-01 | 77.8% | 98.0% |
| 6feaB01 | 3.40.50.1980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain | 0.60 | 41.0 | 4.64e-01 | 94.1% | 88.4% |
| 6feaA01 | 3.40.50.1980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain | 0.60 | 41.0 | 4.11e-01 | 94.1% | 66.8% |
| 1yt8A04 | 3.40.250.10 | Alpha Beta › 3-Layer(aba) Sandwich › Oxidized Rhodanese; domain 1 › Rhodanese-like domain | 0.59 | 32.0 | 3.96e-01 | 82.7% | 86.9% |
| 2ynmD01 | 3.40.50.1980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain | 0.58 | 38.0 | 4.22e-01 | 94.1% | 82.3% |
| 5ljwB01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.58 | 46.0 | 4.98e-01 | 93.0% | 98.1% |
| 6ioyC02 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.58 | 44.0 | 4.28e-01 | 77.8% | 97.5% |
| 2rbgA00 | 3.40.50.11100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.56 | 36.0 | 4.34e-01 | 84.3% | 97.6% |
| 3lucA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.56 | 37.0 | 4.32e-01 | 93.5% | 96.9% |
| 2wvsA01 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.54 | 43.0 | 3.58e-01 | 84.9% | 74.2% |
| 4b28A01 | 3.40.350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Creatine Amidinohydrolase; Chain A, domain 1 › Creatinase/prolidase N-terminal domain | 0.53 | 38.0 | 3.76e-01 | 74.6% | 70.4% |
| 3igqC00 | 2.70.170.10 | Mainly Beta › Distorted Sandwich › Acetylcholine Binding Protein; Chain: A, › Neurotransmitter-gated ion-channel ligand-binding domain | 0.52 | 37.0 | 3.76e-01 | 71.9% | 97.3% |
| 3erpA01 | 3.20.20.100 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › NADP-dependent oxidoreductase domain | 0.52 | 42.0 | 3.60e-01 | 84.9% | 80.3% |
| 2itmB02 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.52 | 46.0 | 4.26e-01 | 94.1% | 85.9% |
| 7v8uA01 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.52 | 48.0 | 4.34e-01 | 100.0% | 99.6% |
| 7zr3A01 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.52 | 47.0 | 3.98e-01 | 100.0% | 83.7% |
| 2vzoA03 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.51 | 41.0 | 3.40e-01 | 85.4% | 84.7% |
| 3fysA01 | 3.40.50.10170 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.51 | 40.0 | 4.35e-01 | 93.0% | 98.0% |
| 4aibA02 | 3.20.20.10 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase | 0.51 | 34.0 | 3.22e-01 | 75.7% | 56.7% |
ECOD (50)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1311096 | 2484.1.1.28 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pack_C | 0.88 | 84.0 | 7.81e-01 | 97.3% | 88.6% |
| 5070445 | 2484.1.1.38 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › eRF1_2 | 0.75 | 48.0 | 5.82e-01 | 93.0% | 97.5% |
| 4147566 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.74 | 46.0 | 5.67e-01 | 94.1% | 96.7% |
| 4979608 | 2484.1.1.38 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › eRF1_2 | 0.74 | 48.0 | 5.75e-01 | 91.9% | 96.8% |
| 4969626 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.73 | 47.0 | 5.66e-01 | 94.6% | 96.0% |
| 5002634 | 2484.1.1.77 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Terminase_6C | 0.73 | 64.0 | 6.49e-01 | 96.8% | 93.9% |
| 4937734 | 2484.1.1.38 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › eRF1_2 | 0.72 | 44.0 | 5.50e-01 | 93.5% | 98.3% |
| 3742154 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.70 | 41.0 | 5.20e-01 | 71.4% | 100.0% |
| 5007927 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.69 | 47.0 | 5.46e-01 | 97.3% | 95.5% |
| 3169931 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.68 | 48.0 | 5.21e-01 | 93.5% | 85.2% |
| 3689980 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.68 | 50.0 | 4.70e-01 | 75.1% | 100.0% |
| 5059158 | 2484.1.1.38 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › eRF1_2 | 0.68 | 47.0 | 5.38e-01 | 93.0% | 95.6% |
| 1149727 | 2484.1.1.21 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › BcrAD_BadFG | 0.68 | 39.0 | 5.04e-01 | 91.9% | 100.0% |
| 3733618 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.66 | 51.0 | 5.03e-01 | 78.9% | 99.5% |
| 4001801 | 2484.1.1.2 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin | 0.65 | 42.0 | 5.10e-01 | 74.6% | 99.2% |
| 4437562 | 2006.1.3.6 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim_2 | 0.65 | 41.0 | 4.84e-01 | 100.0% | 92.0% |
| 3601539 | 2484.1.1.26 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Piwi | 0.63 | 52.0 | 4.84e-01 | 86.5% | 84.8% |
| 4144736 | 2484.1.1.37 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Pan_kinase | 0.62 | 39.0 | 4.80e-01 | 74.6% | 100.0% |
| 4054263 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.62 | 43.0 | 3.88e-01 | 70.3% | 92.9% |
| 3514061 | 2484.1.1.99 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Peptidase_A17 | 0.61 | 54.0 | 5.60e-01 | 99.5% | 100.0% |
| 4229239 | 2484.1.1.85 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC_III | 0.61 | 53.0 | 4.87e-01 | 94.1% | 71.9% |
| 3379915 | 2484.1.1.26 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Piwi | 0.61 | 50.0 | 4.37e-01 | 86.5% | 78.2% |
| 4986006 | 2484.1.1.333 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF1464 | 0.61 | 47.0 | 4.50e-01 | 79.5% | 88.1% |
| 3732367 | 2484.1.1.26 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Piwi | 0.61 | 50.0 | 4.18e-01 | 85.9% | 78.4% |
| 2664650 | 2007.1.14.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › Oxidored_nitro | 0.60 | 41.0 | 4.38e-01 | 94.1% | 77.8% |
| 4489261 | 2007.1.14.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › Oxidored_nitro | 0.60 | 40.0 | 4.19e-01 | 94.1% | 72.9% |
| 3647053 | 2484.1.1.26 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Piwi | 0.60 | 47.0 | 4.67e-01 | 82.2% | 94.4% |
| 5006135 | 2484.1.1.6 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › FGGY_N | 0.59 | 51.0 | 3.71e-01 | 91.4% | 90.3% |
| 3466452 | 2484.1.1.10 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD | 0.59 | 50.0 | 4.42e-01 | 89.2% | 98.8% |
| 4130494 | 2484.1.1.55 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › UvrC_RNaseH_dom | 0.59 | 44.0 | 4.60e-01 | 84.3% | 86.1% |
| 4986944 | 7592.1.1.3 ↗ | a/b three-layered sandwiches › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › DUF6293_N | 0.57 | 36.0 | 3.97e-01 | 90.8% | 78.0% |
| 3807885 | 2006.1.3.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain | 0.55 | 40.0 | 3.03e-01 | 100.0% | 31.0% |
| 5050225 | 2004.1.1.211 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › CLP1_P | 0.55 | 45.0 | 4.31e-01 | 85.4% | 77.6% |
| 3713154 | 2005.1.1.0 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains | 0.55 | 39.0 | 4.38e-01 | 96.2% | 93.8% |
| 4649119 | 2484.1.1.153 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF1744 | 0.54 | 44.0 | 3.81e-01 | 94.6% | 56.4% |
| 4978343 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.54 | 48.0 | 4.26e-01 | 93.5% | 86.7% |
| 5046203 | 2484.1.1.32 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › FGGY_C | 0.54 | 48.0 | 4.32e-01 | 94.1% | 88.8% |
| 139864 | 2002.1.1.51 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Alpha_L_fucos | 0.54 | 44.0 | 3.54e-01 | 84.9% | 70.7% |
| 4999489 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.54 | 48.0 | 4.37e-01 | 94.1% | 87.9% |
| 3943292 | 2484.1.1.32 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › FGGY_C | 0.53 | 47.0 | 4.25e-01 | 94.1% | 83.2% |
| 3732773 | 2484.1.1.220 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF27033 | 0.53 | 46.0 | 4.39e-01 | 91.9% | 95.7% |
| 4958380 | 2484.1.1.199 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Transposase_mut | 0.53 | 48.0 | 4.13e-01 | 97.3% | 81.4% |
| 3962864 | 7564.1.1.1 ↗ | a/b three-layered sandwiches › Homo-oligomeric flavin-containing Cys decarboxylases, HFCD › Homo-oligomeric flavin-containing Cys decarboxylases, HFCD › Homo-oligomeric flavin-containing Cys decarboxylases, HFCD › Flavoprotein | 0.52 | 34.0 | 3.93e-01 | 100.0% | 91.5% |
| 3296792 | 2484.1.1.165 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.52 | 49.0 | 3.87e-01 | 100.0% | 66.7% |
| 4417589 | 2484.1.1.199 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Transposase_mut | 0.52 | 47.0 | 4.77e-01 | 96.2% | 100.0% |
| 4958309 | 2484.1.1.199 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Transposase_mut | 0.52 | 47.0 | 4.60e-01 | 97.3% | 99.5% |
| 5035571 | 2002.1.1.96 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › S-methyl_trans | 0.52 | 44.0 | 3.77e-01 | 90.8% | 92.5% |
| 5076144 | 2002.1.1.74 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Meth_synt_2 | 0.52 | 46.0 | 3.81e-01 | 97.3% | 86.5% |
| 5050900 | 2484.1.1.32 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › FGGY_C | 0.51 | 45.0 | 4.01e-01 | 94.1% | 86.3% |
| 3251214 | 7579.1.1.58 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › DUF829 | 0.51 | 46.0 | 4.11e-01 | 99.5% | 93.6% |
D3
medium
residues 138-212
Domain cluster:
rep: cleavage_packaging_protein__YP_004207870__Cricetid_gammaherpesvirus_2__1605972__D137-212
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02500.23 best | DNA_pack_N | 74.8 | 1.30e-20 | 100.0% | 28.4% |
D4
medium
residues 213-356
Domain cluster:
rep: KX578043.1__AOT27930.1__X__00015__D87-267
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03237.22 best | Terminase_6N | 33.2 | 6.00e-08 | 95.8% | 51.6% |
| PF02500.23 | DNA_pack_N | 190.1 | 9.30e-56 | 68.8% | 36.5% |
D5
medium
residues 357-423
D6
medium
residues 441-455_620-661
Domain cluster:
rep: DNA_packaging_terminase_subunit_1__YP_004940252__Saimiriine_betaherpesvirus_4__1535247__D425-441_605-646
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02499.23 best | DNA_pack_C | 47.8 | 1.60e-12 | 91.2% | 12.2% |