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ORF2

Euk-Vir

Human_gammaherpesvirus_8

ORF2__YP_001129359__Human_gammaherpesvirus_8__37296

Identity

Accession:
YP_001129359 ↗
Protein ID:
ORF2
Kingdom:
euk

Quality

88.2 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Rhadinovirus› Human_gammaherpesvirus_8

TaxID: 37296

Cluster

View cluster (29 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 5-183
PDB
Domain cluster: rep: dihydrofolate_reductase__YP_009119754__Pandoravirus_inopinatum__1605721__D21-210
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00186.25 best DHFR_1 91.2 7.80e-26 99.4% 89.9%
CATH (59)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1bozA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.95 93.0 9.23e-01 100.0% 96.8%
3k2hA01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.92 88.0 8.66e-01 100.0% 93.6%
6pf8A01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.92 85.0 8.66e-01 100.0% 97.2%
5eccA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.92 76.0 8.18e-01 100.0% 97.5%
3nzbX00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.91 89.0 8.38e-01 100.0% 95.6%
2w9hA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.91 76.0 8.18e-01 100.0% 98.1%
3ix9A00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.91 79.0 8.24e-01 100.0% 96.4%
4eckA01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.90 86.0 8.63e-01 100.0% 97.8%
1dhiA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.90 76.0 8.10e-01 100.0% 98.1%
1vdrA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.90 75.0 8.03e-01 100.0% 98.1%
1ao8A00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.90 77.0 8.12e-01 100.0% 98.1%
1j3jB00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.89 87.0 8.03e-01 100.0% 93.5%
3vcoA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.88 85.0 8.42e-01 100.0% 96.7%
1aoeA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.86 84.0 8.14e-01 100.0% 96.4%
1cz3B00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.85 74.0 7.62e-01 100.0% 95.2%
2h2qB01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.82 80.0 7.45e-01 100.0% 87.7%
2xw7A00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.80 72.0 7.29e-01 100.0% 95.4%
1juvA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.79 76.0 7.41e-01 100.0% 99.5%
2p4gA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.79 76.0 6.63e-01 100.0% 90.3%
3ky8A01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.79 72.0 7.34e-01 100.0% 98.9%
3jtwA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.79 72.0 7.27e-01 100.0% 97.2%
3kgyA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.77 74.0 6.83e-01 100.0% 95.0%
3zpgA02 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.76 73.0 6.77e-01 100.0% 93.1%
2b3zA02 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.76 73.0 6.63e-01 100.0% 93.3%
2aznA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.76 73.0 6.71e-01 100.0% 96.3%
2hxvA02 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.75 72.0 6.95e-01 100.0% 98.0%
2g6vA02 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.73 70.0 6.43e-01 100.0% 93.2%
2gd9A01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.73 64.0 6.63e-01 99.4% 98.8%
4xt6A00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.73 69.0 6.22e-01 100.0% 87.8%
4ha7B00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.68 65.0 6.19e-01 100.0% 86.8%
2yn0A00 3.40.50.1240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate mutase-like 0.63 50.0 4.46e-01 82.1% 98.0%
2qe6A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.62 53.0 4.65e-01 92.7% 93.2%
2vdwG00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.61 52.0 4.54e-01 91.6% 95.7%
5b7hB01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.61 28.0 3.54e-01 100.0% 69.4%
6z6fA01 3.40.800.20 Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Histone deacetylase domain 0.59 48.0 3.77e-01 84.4% 90.8%
6fu1A00 3.40.800.20 Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Histone deacetylase domain 0.59 48.0 3.74e-01 86.0% 83.0%
4gvlA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.58 38.0 4.26e-01 76.0% 84.6%
2px0A02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 50.0 5.03e-01 99.4% 89.2%
5dzsB02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.58 41.0 4.66e-01 91.1% 98.5%
3busB00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.58 49.0 4.46e-01 91.6% 98.8%
7fbhB01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 48.0 4.41e-01 91.6% 95.4%
1yc5A01 3.40.50.1220 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain 0.56 40.0 4.32e-01 73.7% 86.7%
4pneA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 48.0 4.20e-01 92.7% 91.1%
1nv8A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 47.0 4.62e-01 91.6% 91.4%
1kpgD00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 47.0 4.07e-01 92.7% 95.8%
7cluA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 46.0 4.31e-01 92.2% 84.6%
3oy2A01 3.40.50.11930 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.54 41.0 4.33e-01 78.8% 96.9%
1xdzA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 46.0 4.20e-01 92.2% 73.5%
5fcdA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 45.0 4.17e-01 90.5% 98.7%
2bkyX00 3.30.110.20 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Alba-like domain 0.53 27.0 3.64e-01 100.0% 96.5%
3b8bA02 3.40.190.80 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › 0.52 30.0 3.65e-01 100.0% 88.3%
2h00B00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.52 44.0 4.20e-01 91.6% 84.8%
3pkiA01 3.40.50.1220 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain 0.52 41.0 3.96e-01 83.2% 83.8%
3l7iA02 3.40.50.12580 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › CDP-glycerol glycerophosphotransferase, C-terminal domain 0.52 40.0 4.06e-01 100.0% 80.9%
3egoA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 38.0 3.96e-01 76.5% 87.7%
5tx7A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 44.0 4.32e-01 91.6% 96.8%
2igtA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 45.0 4.09e-01 96.6% 91.1%
6aieA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 43.0 4.32e-01 92.2% 89.6%
3thxB05 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.50 40.0 3.54e-01 99.4% 57.2%
ECOD (99)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4402042 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.95 93.0 9.25e-01 100.0% 97.3%
3913441 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.95 93.0 9.10e-01 100.0% 95.8%
4276639 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.95 82.0 8.44e-01 100.0% 92.9%
3963884 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.94 80.0 8.55e-01 100.0% 98.1%
3232633 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.93 91.0 9.00e-01 100.0% 97.8%
3360231 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.93 89.0 8.18e-01 100.0% 80.0%
3900511 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.92 90.0 8.92e-01 100.0% 96.8%
185430 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.92 88.0 8.70e-01 100.0% 94.1%
4021830 7501.1.1.0 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases 0.92 90.0 8.16e-01 100.0% 97.3%
4392834 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.92 90.0 8.08e-01 100.0% 95.7%
4624802 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.92 79.0 8.34e-01 100.0% 97.5%
10268 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.91 89.0 8.40e-01 100.0% 95.6%
2503171 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.91 85.0 8.55e-01 100.0% 95.5%
4563316 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.91 75.0 7.88e-01 100.0% 91.5%
3631503 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.91 89.0 7.11e-01 100.0% 96.8%
4667474 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.91 88.0 8.84e-01 100.0% 98.9%
169540 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.91 78.0 8.12e-01 100.0% 94.6%
2831687 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.91 77.0 7.92e-01 100.0% 90.2%
137968 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.91 79.0 8.24e-01 100.0% 96.4%
3738384 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.91 88.0 7.79e-01 100.0% 88.7%
2847460 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.91 73.0 7.85e-01 100.0% 94.9%
136031 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.90 88.0 8.12e-01 100.0% 97.7%
3697700 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.90 88.0 7.11e-01 100.0% 97.0%
3611921 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.90 87.0 7.87e-01 100.0% 90.9%
4279950 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.90 78.0 8.16e-01 100.0% 97.0%
4392683 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.90 78.0 8.18e-01 100.0% 97.0%
3593841 7501.1.1.0 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases 0.90 87.0 8.00e-01 100.0% 91.8%
4115051 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.89 87.0 7.69e-01 100.0% 94.6%
4652224 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.89 77.0 8.11e-01 100.0% 97.0%
4965070 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.89 77.0 7.87e-01 100.0% 91.4%
3187913 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.89 86.0 7.95e-01 100.0% 96.8%
4295510 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.88 74.0 7.84e-01 100.0% 96.9%
3056343 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.88 84.0 7.88e-01 100.0% 92.0%
4228699 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.87 84.0 8.07e-01 100.0% 99.5%
4315799 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.85 79.0 8.04e-01 100.0% 97.7%
4123104 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.85 73.0 7.67e-01 100.0% 97.0%
5030442 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.84 76.0 7.80e-01 100.0% 98.2%
3581890 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.83 81.0 7.85e-01 100.0% 95.9%
3590464 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.81 73.0 7.44e-01 100.0% 97.1%
5058063 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.81 73.0 7.41e-01 100.0% 96.6%
3263045 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.81 78.0 7.45e-01 100.0% 93.5%
3010946 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.80 73.0 7.41e-01 100.0% 97.7%
10266 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.79 76.0 7.41e-01 100.0% 99.5%
163852 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.79 76.0 6.63e-01 100.0% 90.3%
137569 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.79 72.0 7.29e-01 100.0% 97.2%
136641 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.79 72.0 7.27e-01 100.0% 97.2%
3289265 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.78 74.0 7.42e-01 100.0% 98.3%
5009586 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.78 74.0 6.97e-01 100.0% 97.1%
3289701 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.78 74.0 6.89e-01 100.0% 97.2%
3385448 7501.1.1.0 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases 0.77 65.0 6.84e-01 100.0% 96.9%
3278932 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.77 73.0 7.21e-01 100.0% 97.4%
4992215 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.77 74.0 6.86e-01 100.0% 96.7%
4487226 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.77 73.0 6.46e-01 100.0% 85.9%
4033392 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.77 73.0 6.91e-01 100.0% 96.7%
5057520 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.77 73.0 6.76e-01 100.0% 91.8%
2389059 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.77 73.0 6.54e-01 100.0% 90.8%
5015705 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.77 73.0 6.63e-01 100.0% 92.6%
4946280 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.77 73.0 6.74e-01 100.0% 97.3%
5001085 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.76 73.0 6.56e-01 100.0% 90.2%
4968801 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.76 73.0 6.60e-01 100.0% 89.1%
3279668 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.76 72.0 7.18e-01 100.0% 97.8%
5073892 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.76 72.0 7.10e-01 100.0% 96.3%
3432837 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.76 72.0 6.57e-01 100.0% 90.0%
4262258 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.76 72.0 6.63e-01 100.0% 93.3%
5048917 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.76 72.0 6.69e-01 100.0% 95.9%
3282327 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.76 72.0 7.00e-01 100.0% 97.4%
4577003 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.76 72.0 6.73e-01 100.0% 96.3%
3737525 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.76 72.0 6.29e-01 100.0% 91.8%
4959428 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.76 72.0 6.59e-01 100.0% 94.2%
5062001 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.75 72.0 6.41e-01 100.0% 90.4%
10273 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.75 72.0 6.95e-01 100.0% 98.0%
5050939 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.75 72.0 6.45e-01 100.0% 94.5%
3287430 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.75 69.0 6.46e-01 96.6% 97.2%
3286316 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.75 71.0 7.05e-01 100.0% 96.8%
3953555 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.75 71.0 7.02e-01 100.0% 96.3%
5063695 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.75 71.0 6.98e-01 100.0% 96.3%
3277763 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.74 70.0 6.96e-01 100.0% 97.3%
3839944 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.74 65.0 6.59e-01 100.0% 92.2%
160146 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.73 64.0 6.53e-01 100.0% 93.8%
4949256 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.73 70.0 6.43e-01 100.0% 97.3%
4980571 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.73 69.0 6.41e-01 100.0% 97.7%
3278543 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.73 69.0 6.74e-01 100.0% 97.4%
3740375 7501.1.1.0 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases 0.72 67.0 6.55e-01 100.0% 98.5%
3349539 2003.1.5.31 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GRAS 0.62 53.0 4.17e-01 91.6% 81.0%
4962546 2003.1.5.33 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0146 0.59 41.0 4.55e-01 87.7% 90.7%
4019786 2003.1.5.151 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23, Methyltransf_25 0.57 49.0 4.19e-01 93.3% 93.1%
3939568 2003.1.5.54 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_10 0.57 48.0 4.16e-01 92.2% 80.0%
4023089 2003.1.5.79 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23 0.56 48.0 4.04e-01 92.7% 84.5%
4135042 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.56 47.0 4.18e-01 92.2% 94.0%
3696524 2003.1.5.151 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23, Methyltransf_25 0.55 48.0 3.98e-01 93.3% 89.2%
3283335 7523.1.1.15 ↗ a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › LysR_substrate 0.55 32.0 3.65e-01 100.0% 74.8%
3960615 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.55 46.0 4.57e-01 89.4% 97.8%
3208986 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.54 43.0 3.70e-01 84.9% 96.3%
4431928 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.54 47.0 3.94e-01 95.5% 88.4%
5001906 2004.1.1.146 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase 0.54 48.0 4.48e-01 97.8% 85.8%
4451549 2003.1.5.15 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › FtsJ 0.53 45.0 4.32e-01 92.2% 89.5%
None — 0.53 45.0 4.30e-01 92.2% 89.0%
4075097 2003.1.5.15 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › FtsJ 0.52 44.0 4.33e-01 92.2% 94.3%
2755275 2003.1.5.32 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Cons_hypoth95 0.52 43.0 4.33e-01 92.2% 88.6%