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ORF2

Euk-Vir

Macaca_nemestrina_rhadinovirus_2

ORF2__YP_010084542__Macaca_nemestrina_rhadinovirus_2__123630

Identity

Accession:
YP_010084542 ↗
Protein ID:
ORF2
Kingdom:
euk

Quality

94.6 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-21_50-126
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00186.25 best DHFR_1 49.5 5.30e-13 86.7% 42.8%
D2 medium residues 22-49_127-185
PDB
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1bozA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.94 89.0 6.67e-01 98.9% 89.2%
3nzbX00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.89 84.0 6.11e-01 98.9% 88.8%
3k2hA01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.85 79.0 5.98e-01 98.9% 86.6%
3vcoA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.84 76.0 5.85e-01 97.7% 90.7%
6pf8A01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.84 77.0 5.94e-01 97.7% 88.1%
1dhiA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.76 69.0 5.55e-01 97.7% 89.3%
3zpgA02 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.64 57.0 4.24e-01 97.7% 86.1%
6nifA01 3.30.900.10 Alpha Beta › 2-Layer Sandwich › Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A › HORMA domain 0.61 51.0 3.93e-01 94.3% 91.2%
3ajdA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.58 47.0 3.71e-01 89.7% 100.0%
1i72A00 3.60.90.10 Alpha Beta › 4-Layer Sandwich › S-adenosylmethionine decarboxylase › S-adenosylmethionine decarboxylase 0.51 44.0 3.19e-01 97.7% 99.2%
2nykA02 2.60.40.2530 Mainly Beta › Sandwich › Immunoglobulin-like › 0.50 31.0 3.17e-01 98.9% 60.9%
1pbyA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.50 31.0 3.33e-01 96.6% 71.1%
ECOD (7)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4402042 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.93 88.0 6.56e-01 97.7% 89.2%
3913441 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.92 88.0 6.56e-01 100.0% 88.9%
4667474 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.89 83.0 6.32e-01 97.7% 90.6%
3900511 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.89 84.0 6.34e-01 100.0% 89.7%
3631503 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.88 83.0 5.45e-01 100.0% 87.1%
3992086 213.1.1.57 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › BCCIP 0.54 44.0 3.19e-01 89.7% 88.8%
4392983 2003.1.5.20 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MethyltransfD12 0.53 43.0 3.14e-01 95.4% 94.0%