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ORF35

Euk-Vir

Alcelaphine_gammaherpesvirus_1

ORF35__NP_065533__Alcelaphine_gammaherpesvirus_1__35252

Identity

Accession:
NP_065533 ↗
Protein ID:
ORF35
Kingdom:
euk

Quality

87.3 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 3-83
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05852.17 best DUF848 102.2 4.00e-29 100.0% 55.2%
CATH (48)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.89 66.0 7.09e-01 76.5% 87.3%
3n71A03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.87 62.0 4.44e-01 74.1% 28.2%
2b5dX01 3.20.110.10 Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain 0.86 58.0 3.59e-01 72.8% 13.9%
1ku9A02 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.86 59.0 6.59e-01 70.4% 100.0%
1st6A02 1.20.120.810 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle 0.86 78.0 5.43e-01 98.8% 33.5%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.85 67.0 6.01e-01 86.4% 61.8%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.85 70.0 6.83e-01 87.7% 84.1%
5fmnA00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.84 68.0 6.66e-01 86.4% 80.2%
4adzA00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.84 66.0 6.37e-01 85.2% 74.4%
2q0oC00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.82 62.0 6.12e-01 80.2% 74.4%
3layF00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.82 62.0 6.37e-01 80.2% 83.3%
2v0xA01 1.10.287.3160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.80 72.0 5.66e-01 100.0% 73.2%
1aj3A00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.79 55.0 5.12e-01 75.3% 59.2%
3l9fA02 6.10.140.1570 Special › Helix non-globular › Helix Hairpins › 0.79 54.0 5.48e-01 71.6% 71.6%
1m62A00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.78 53.0 5.16e-01 75.3% 64.4%
3r84B00 6.10.280.160 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 0.78 64.0 6.51e-01 92.6% 88.7%
4a4kA01 1.20.1500.20 Mainly Alpha › Up-down Bundle › YheA-like fold › 0.78 52.0 4.62e-01 70.4% 49.6%
3hr0B01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.77 60.0 6.12e-01 82.7% 84.8%
1ij5A01 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 60.0 6.22e-01 96.3% 90.8%
4ke2A00 6.10.140.1860 Special › Helix non-globular › Helix Hairpins › 0.76 68.0 5.03e-01 96.3% 42.3%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 65.0 5.96e-01 91.4% 72.5%
1urfA00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.76 61.0 6.14e-01 88.9% 86.4%
1wleA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.76 62.0 5.47e-01 90.1% 61.4%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.75 58.0 4.40e-01 81.5% 96.2%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.75 53.0 5.11e-01 79.0% 64.8%
4nb5B02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.74 54.0 5.94e-01 77.8% 98.4%
4h63H01 1.20.58.1710 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 55.0 5.83e-01 79.0% 88.9%
4nsmA00 6.10.250.2770 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.74 54.0 5.81e-01 77.8% 87.3%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.73 65.0 4.39e-01 100.0% 27.5%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.73 57.0 5.83e-01 82.7% 88.3%
1jadA00 1.20.1230.10 Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain 0.72 65.0 4.56e-01 97.5% 36.0%
1ylmA00 1.20.120.580 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like 0.72 53.0 4.34e-01 77.8% 43.7%
3okqA00 1.20.58.1540 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain 0.71 62.0 5.40e-01 98.8% 88.8%
3syvA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.70 63.0 4.49e-01 100.0% 35.5%
3ehfD01 1.20.5.1930 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.70 49.0 5.41e-01 74.1% 93.7%
3qo8A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.70 54.0 5.00e-01 87.7% 64.2%
3eslA01 1.20.58.2070 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 41.0 4.30e-01 70.4% 62.7%
1yg2A02 6.10.140.190 Special › Helix non-globular › Helix Hairpins › 0.70 51.0 5.01e-01 81.5% 71.1%
6r1nA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.70 56.0 5.18e-01 87.7% 68.9%
2cazD00 6.10.140.820 Special › Helix non-globular › Helix Hairpins › 0.69 49.0 5.42e-01 75.3% 100.0%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 54.0 4.81e-01 88.9% 59.2%
3nrxA00 1.20.58.1520 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 63.0 5.39e-01 100.0% 77.2%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 53.0 5.36e-01 86.4% 86.4%
3pltA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.67 59.0 4.30e-01 96.3% 62.6%
4okvE00 6.10.140.1890 Special › Helix non-globular › Helix Hairpins › 0.65 45.0 5.04e-01 79.0% 89.2%
1t7sA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.62 52.0 4.56e-01 100.0% 59.7%
1ykhA00 6.10.140.200 Special › Helix non-globular › Helix Hairpins › 0.60 50.0 4.81e-01 96.3% 86.3%
2x6hA03 1.10.1070.11 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › Phosphatidylinositol 3-/4-kinase, catalytic domain 0.51 38.0 2.95e-01 82.7% 48.5%
ECOD (44)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3657787 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.92 73.0 5.16e-01 84.0% 31.2%
4034363 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.92 72.0 6.38e-01 81.5% 84.5%
3279558 192.31.1.5 alpha bundles › Long alpha-hairpin › CP12 › CP12 › DUF4254 0.90 62.0 5.45e-01 70.4% 61.8%
3269731 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.90 76.0 6.62e-01 88.9% 66.1%
4629385 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.88 83.0 6.55e-01 100.0% 58.7%
3593583 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.86 80.0 6.65e-01 100.0% 62.2%
3964486 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.86 81.0 6.27e-01 100.0% 55.0%
3677853 109.4.1.1529 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › eIF3_p135, TPR_12 0.85 60.0 3.38e-01 100.0% 7.7%
1002194 192.23.1.1 alpha bundles › Long alpha-hairpin › DUF683 › DUF683 › Rop-like 0.84 61.0 6.50e-01 75.3% 85.9%
3386700 304.58.1.0 a+b two layers › Alpha-beta plaits › FepE-like › FepE-like 0.84 66.0 4.36e-01 82.7% 22.7%
3477822 1147.1.1.1 alpha bundles › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › Occludin_ELL 0.83 62.0 5.23e-01 77.8% 50.4%
3571433 3939.1.1.220 alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › KIF21A 0.83 77.0 6.00e-01 100.0% 51.9%
4000107 3567.1.1.122 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › BAR 0.82 75.0 5.94e-01 100.0% 80.0%
3550353 3602.1.1.0 alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain 0.82 57.0 6.27e-01 71.6% 100.0%
3610706 3602.1.1.0 alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain 0.81 59.0 5.98e-01 75.3% 76.2%
3428894 604.5.1.39 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PF26581 0.80 69.0 5.73e-01 96.3% 54.3%
3735607 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.80 64.0 6.48e-01 86.4% 86.3%
3249343 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.79 71.0 5.11e-01 98.8% 55.6%
3235839 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.78 73.0 5.56e-01 100.0% 76.0%
3785883 4177.1.1.97 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › PF30147 0.78 70.0 5.27e-01 96.3% 83.8%
3900975 604.1.1.92 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › SR_desmoplakin_3 0.78 62.0 5.25e-01 85.2% 53.1%
3386594 3291.1.1.197 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › MCPsignal 0.78 66.0 6.02e-01 92.6% 80.0%
4234530 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.77 65.0 5.75e-01 91.4% 64.3%
3435097 4177.1.1.11 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › DUF632 0.77 70.0 4.81e-01 100.0% 46.4%
3831 604.7.1.1 alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA 0.76 65.0 5.96e-01 91.4% 72.5%
3181110 5086.1.1.110 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HisKA 0.76 65.0 6.18e-01 92.6% 78.9%
5066104 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.76 68.0 4.08e-01 100.0% 39.6%
3404270 377.1.1.0 few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like 0.75 61.0 5.17e-01 87.7% 76.2%
3235225 4177.1.1.5 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 0.75 66.0 4.75e-01 96.3% 37.3%
5084060 3755.3.1.637 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 0.74 66.0 5.27e-01 96.3% 86.5%
3254670 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.74 65.0 4.69e-01 96.3% 36.9%
4027748 3291.1.1.1 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 0.74 66.0 5.46e-01 100.0% 59.3%
3385727 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.74 67.0 4.62e-01 100.0% 32.2%
3350900 109.4.1.148 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › EST1_DNA_bind,EST1 0.73 66.0 3.89e-01 97.5% 22.6%
3727276 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.73 51.0 4.94e-01 72.8% 67.4%
3355246 192.1.1.0 alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain 0.72 55.0 5.61e-01 86.4% 83.7%
3598168 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.72 63.0 5.02e-01 98.8% 49.7%
3780286 244.1.1.6 a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C › Amino_oxidase 0.72 60.0 3.60e-01 96.3% 13.3%
4660205 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.72 62.0 5.24e-01 96.3% 87.4%
3933048 4992.1.1.12 extended segments › RelB-like › RelB-like › RelB-like › LIN9_C 0.71 60.0 5.56e-01 92.6% 76.0%
5033276 101.1.2.14 alpha arrays › HTH › HTH › winged helix domain › HTH_5 0.69 52.0 4.29e-01 82.7% 47.0%
4396574 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.68 55.0 4.32e-01 86.4% 88.4%
3732397 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.66 56.0 4.94e-01 95.1% 75.8%
3750377 605.1.1.254 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › MRVI1 0.62 50.0 5.03e-01 86.4% 88.7%