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ORF3
Euk-VirCoronavirus_AcCoV-JC34
ORF3__YP_009380522__Coronavirus_AcCoV-JC34__1964806
Identity
- Accession:
- YP_009380522 ↗
- Protein ID:
- ORF3
- Kingdom:
- euk
Quality
76.1
mean pLDDT
Taxonomy
Orthornavirae›
Pisuviricota›
Pisoniviricetes›
Nidovirales›
Coronaviridae›
Alphacoronavirus›
Coronavirus_AcCoV-JC34
TaxID: 1964806
Cluster
View cluster (89 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 10-119
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03053.20 best | Corona_NS3b | 65.2 | 1.00e-17 | 83.6% | 34.5% |
CATH (20)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1ya0A01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.67 | 46.0 | 3.73e-01 | 70.0% | 42.2% |
| 3r2kA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.66 | 46.0 | 4.16e-01 | 72.7% | 92.2% |
| 7e9uA01 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.64 | 48.0 | 3.17e-01 | 78.2% | 21.5% |
| 4rngC00 | 1.20.1280.290 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.63 | 45.0 | 5.06e-01 | 79.1% | 100.0% |
| 1dpsA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.62 | 46.0 | 4.06e-01 | 77.3% | 92.5% |
| 3tp3A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.62 | 44.0 | 3.97e-01 | 72.7% | 73.6% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.61 | 45.0 | 4.31e-01 | 87.3% | 65.6% |
| 2chpA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.61 | 43.0 | 3.90e-01 | 72.7% | 99.3% |
| 2lxlA00 | 1.25.40.270 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 | 0.60 | 43.0 | 3.81e-01 | 76.4% | 50.3% |
| 1r3bA01 | 1.20.140.30 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › MOB kinase activator | 0.60 | 46.0 | 3.94e-01 | 80.9% | 92.0% |
| 1avoB00 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.60 | 41.0 | 3.82e-01 | 70.9% | 69.3% |
| 2qqyA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.59 | 42.0 | 3.90e-01 | 73.6% | 100.0% |
| 3t9jA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.58 | 40.0 | 3.70e-01 | 70.9% | 99.3% |
| 1uz3B00 | 1.10.1240.40 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › ENT domain | 0.55 | 42.0 | 4.50e-01 | 88.2% | 92.8% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.55 | 40.0 | 3.80e-01 | 77.3% | 67.7% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.54 | 40.0 | 3.83e-01 | 78.2% | 81.5% |
| 1sr2A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.53 | 37.0 | 3.67e-01 | 88.2% | 67.2% |
| 1lkoA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.51 | 45.0 | 4.15e-01 | 98.2% | 95.9% |
| 3o7qA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.50 | 37.0 | 3.16e-01 | 78.2% | 50.5% |
| 3hiuD00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.50 | 43.0 | 3.87e-01 | 93.6% | 93.4% |
ECOD (16)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3943720 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.73 | 51.0 | 4.67e-01 | 70.9% | 79.3% |
| 3708344 | 604.1.1.160 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › DYH2-5-8_CC | 0.72 | 55.0 | 5.20e-01 | 80.0% | 86.2% |
| 3176334 | 109.4.1.44 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps35 | 0.69 | 51.0 | 3.59e-01 | 89.1% | 24.6% |
| 3581026 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.67 | 53.0 | 4.94e-01 | 84.5% | 93.3% |
| 3925829 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.66 | 52.0 | 5.25e-01 | 84.5% | 97.3% |
| 3195624 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.65 | 47.0 | 4.27e-01 | 77.3% | 76.8% |
| 3580982 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.65 | 51.0 | 5.05e-01 | 84.5% | 100.0% |
| 3690615 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.63 | 48.0 | 4.61e-01 | 81.8% | 76.2% |
| 5079010 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.61 | 44.0 | 4.06e-01 | 75.5% | 62.8% |
| 4939717 | 3758.2.1.1 ↗ | alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB | 0.61 | 46.0 | 3.80e-01 | 79.1% | 85.5% |
| 3706306 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.58 | 44.0 | 4.31e-01 | 82.7% | 74.2% |
| 4011321 | 7087.1.1.0 ↗ | alpha bundles › Emopamil binding protein (EBP) transmembrane domain › Emopamil binding protein (EBP) transmembrane domain › Emopamil binding protein (EBP) transmembrane domain | 0.58 | 48.0 | 3.80e-01 | 91.8% | 98.3% |
| 3244235 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.57 | 42.0 | 4.34e-01 | 77.3% | 90.0% |
| 4928931 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.57 | 44.0 | 4.06e-01 | 81.8% | 79.3% |
| 3932690 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.56 | 42.0 | 4.61e-01 | 81.8% | 98.9% |
| 3216931 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.56 | 49.0 | 4.09e-01 | 99.1% | 55.0% |
D2
high
residues 123-198
Domain cluster:
rep: putative_membrane_protein__YP_009408173__Morelia_viridis_nidovirus__2016400__D128-203
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03053.20 best | Corona_NS3b | 67.7 | 1.80e-18 | 100.0% | 33.2% |